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https://www.readbyqxmd.com/read/28107703/how-universal-is-coverage-and-access-to-diagnosis-and-treatment-for-chagas-disease-in-colombia-a-health-systems-analysis
#1
Zulma M Cucunubá, Jennifer M Manne-Goehler, Diana Díaz, Pierre Nouvellet, Oscar Bernal, Andrea Marchiol, María-Gloria Basáñez, Lesong Conteh
Limited access to Chagas disease diagnosis and treatment is a major obstacle to reaching the 2020 World Health Organization milestones of delivering care to all infected and ill patients. Colombia has been identified as a health system in transition, reporting one of the highest levels of health insurance coverage in Latin America. We explore if and how this high level of coverage extends to those with Chagas disease, a traditionally marginalised population. Using a mixed methods approach, we calculate coverage for screening, diagnosis and treatment of Chagas...
January 4, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28107687/do-recreational-cannabis-users-unlicensed-and-licensed-medical-cannabis-users-form-distinct-groups
#2
Sharon R Sznitman
BACKGROUND: This study aims to gain a more nuanced perspective on the differences between recreationally and medically motivated cannabis use by distinguishing between people who use cannabis for recreational purposes, unlicensed and licensed medical users. METHODS: Data collection was conducted online from a convenience sample of 1479 Israeli cannabis users. Multinomial regression analysis compared unlicensed medical users (38%) with recreational (42%) and licensed medical (5...
January 17, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28107670/pharmaceutical-opioid-use-among-oral-and-intravenous-users-in-australia-a-qualitative-comparative-study
#3
George Dertadian, Jenny Iversen, Thomas C Dixon, Katrina Sotiropoulos, Lisa Maher
BACKGROUND: Between 1992 and 2012 dispensing episodes for pharmaceutical opioids (PO) in Australia increased from 500000 to 7500000. In the US, increases in the prescription of PO have been linked to increases in opioid-related morbidity and mortality and transitions to heroin injection. However, Australian data indicate that morbidity and mortality related to PO are relatively low, particularly when compared to heroin and other drugs. This paper explores the characteristics and patterns of non-medical pharmaceutical opioid (NMPO) use among a sample of young people in Sydney, Australia...
January 17, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28107604/predicting-recovery-in-patients-with-acute-low-back-pain-a-clinical-prediction-model
#4
T da Silva, P Macaskill, K Mills, C Maher, C Williams, C Lin, M J Hancock
BACKGROUND: There is substantial variability in the prognosis of acute low back pain (LBP). The ability to identify the probability of individual patients recovering by key time points would be valuable in making informed decisions about the amount and type of treatment to provide. Predicting recovery based on presentation 1-week after initially seeking care is clinically important and may be more accurate than predictions made at initial presentation. The aim of this study was to predict the probability of recovery at 1-week, 1-month and 3-months after 1-week review in patients who still have LBP 1-week after initially seeking care...
January 20, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/28107585/treatment-and-primary-prevention-in-people-who-inject-drugs-for-chronic-hepatitis-c-infection-is-elimination-possible-in-a-high-prevalence-setting
#5
I Gountas, V Sypsa, O Anagnostou, N K Martin, P Vickerman, E Kafetzopoulos, A Hatzakis
AIMS: To project the impact of scaling up oral antiviral therapy and harm reduction on chronic hepatitis C (CHC) prevalence and incidence among people who inject drugs (PWID) in Greece, to estimate the relationship between required treatment levels and expansion of harm reduction programs to achieve specific targets and to examine whether hepatitis C viruse (HCV) elimination among PWID is possible in this high prevalence setting. DESIGN: A dynamic discrete time, stochastic individual-based model was developed to simulate HCV transmission among PWID incorporating the effect of HCV treatment and harm reduction strategies, and allowing for reinfection following treatment...
January 20, 2017: Addiction
https://www.readbyqxmd.com/read/28107561/beta-blockers-for-hypertension
#6
REVIEW
Charles S Wiysonge, Hazel A Bradley, Jimmy Volmink, Bongani M Mayosi, Lionel H Opie
BACKGROUND: Beta-blockers refer to a mixed group of drugs with diverse pharmacodynamic and pharmacokinetic properties. They have shown long-term beneficial effects on mortality and cardiovascular disease (CVD) when used in people with heart failure or acute myocardial infarction. Beta-blockers were thought to have similar beneficial effects when used as first-line therapy for hypertension. However, the benefit of beta-blockers as first-line therapy for hypertension without compelling indications is controversial...
January 20, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28107457/novel-analysis-of-immune-cells-from-nasal-microbiopsy-demonstrates-reliable-reproducible-data-for-immune-populations-and-superior-cytokine-detection-compared-to-nasal-wash
#7
Simon P Jochems, Katherine Piddock, Jamie Rylance, Hugh Adler, Beatriz F Carniel, Andrea Collins, Jenna F Gritzfeld, Carole Hancock, Helen Hill, Jesus Reiné, Alexandra Seddon, Carla Solórzano, Syba Sunny, Ashleigh Trimble, Angela D Wright, Seher Zaidi, Stephen B Gordon, Daniela M Ferreira
The morbidity and mortality related to respiratory tract diseases is enormous, with hundreds of millions of individuals afflicted and four million people dying each year. Understanding the immunological processes in the mucosa that govern outcome following pathogenic encounter could lead to novel therapies. There is a need to study responses at mucosal surfaces in humans for two reasons: (i) Immunological findings in mice, or other animals, often fail to translate to humans. (ii) Compartmentalization of the immune system dictates a need to study sites where pathogens reside...
2017: PloS One
https://www.readbyqxmd.com/read/28107449/the-impact-of-shame-self-criticism-and-social-rank-on-eating-behaviours-in-overweight-and-obese-women-participating-in-a-weight-management-programme
#8
Cristiana Duarte, Marcela Matos, R James Stubbs, Corinne Gale, Liam Morris, Jose Pinto Gouveia, Paul Gilbert
Recent research has suggested that obesity is a stigmatised condition. Concerns with personal inferiority (social rank), shame and self-criticism may impact on weight management behaviours. The current study examined associations between social comparison (shame, self-criticism), negative affect and eating behaviours in women attending a community based weight management programme focused on behaviour change. 2,236 participants of the programme completed an online survey using measures of shame, self-criticism, social comparison, and weight-related affect, which were adapted to specifically address eating behaviour, weight and body shape perceptions...
2017: PloS One
https://www.readbyqxmd.com/read/28107417/is-variety-the-spice-of-life-an-experimental-investigation-into-the-effects-of-species-richness-on-self-reported-mental-well-being
#9
Lukas J Wolf, Sophus Zu Ermgassen, Andrew Balmford, Mathew White, Netta Weinstein
Losses in biodiversity and trends toward urbanisation have reduced people's contact with biodiverse nature, yet the consequences for mental well-being are not well understood. Here, we demonstrate that greater plant and animal species richness in isolation causes an improvement in mental well-being. To do so, the present research experimentally manipulated species richness and assessed widely-used indicators of mental well-being. Participants viewed short videos of either high or low tree (Study 1) or bird (Study 2) species richness and reported on positive (i...
2017: PloS One
https://www.readbyqxmd.com/read/28107401/how-many-patients-become-functionally-dependent-after-a-stroke-a-3-year-population-based-study-in-joinville-brazil
#10
Lívia Mizuki de Campos, Bruna Mariah Martins, Norberto Luiz Cabral, Selma Cristina Franco, Octávio Marques Pontes-Neto, Suleimy Cristina Mazin, Felipe Ibiapina Dos Reis
The decrease in stroke mortality will increase the burden of survivors with functional dependence (FD). The aim of this study was to evaluate how many patients become functionally dependent over 3 years after an incident event in Joinville, Brazil. The proportion of FD (defined as a modified Rankin score 3 to 5) among stroke survivors from the Joinville Stroke Registry was assessed using a validated telephone interview. Incidence of FD after stroke in Joinville in one year was 23.24 per 100,000 population. The overall proportion of FD among stroke survivors at discharge was 32...
2017: PloS One
https://www.readbyqxmd.com/read/28107400/when-contact-is-not-enough-affecting-first-year-medical-students-image-towards-older-persons
#11
Sasmita Kusumastuti, Esther van Fenema, Eugenie C F Polman-van Stratum, Wilco Achterberg, Jolanda Lindenberg, Rudi G J Westendorp
CONTEXT: Many medical schools have initiated care internships to familiarize their students with older persons and to instil a professional attitude. OBJECTIVE: To examine the impact of care internships on the image that first-year medical students have of older persons and to explore the underlying concepts that may play a role in shaping this image. DESIGN: Survey before and after a two-week compulsory care internship using the Aging Semantic Differential (ASD; 32 adjectives) and the Attitudes toward Old People (AOP; 34 positions) questionnaires...
2017: PloS One
https://www.readbyqxmd.com/read/28107387/neuronal-cell-death-and-degeneration-through-increased-nitroxidative-stress-and-tau-phosphorylation-in-hiv-1-transgenic-rats
#12
Young-Eun Cho, Myoung-Hwa Lee, Byoung-Joon Song
The underlying mechanisms for increased neurodegeneration and neurocognitive deficits in HIV-infected people are unclear. Therefore, this study was aimed to investigate the mechanisms of increased neurodegeneration in 5-month old male HIV-1 Transgenic (Tg) rats compared to the age- and gender-matched wild-type (WT) by evaluating histological changes and biochemical parameters of the key proteins involved in the cell death signaling and apoptosis. Histological and immunohistochemical analyses revealed decreased neuronal cells with elevated astrogliosis in HIV-1 Tg rats compared to WT...
2017: PloS One
https://www.readbyqxmd.com/read/28107374/combining-social-norms-and-social-marketing-to-address-underage-drinking-development-and-process-evaluation-of-a-whole-of-community-intervention
#13
Sandra C Jones, Kelly Andrews, Kate Francis
Youth alcohol consumption has been steadily declining in Australia, as in other countries; fewer young people are drinking and the age of initiation is increasing. However, young people, their parents and others in their communities continue to believe that adolescent (excessive) drinking is the norm. This perception, and the concurrent misperception that the majority of parents are happy to provide their underage children with alcohol, creates a perceived culture of acceptance of youth alcohol consumption...
2017: PloS One
https://www.readbyqxmd.com/read/28107372/cohort-randomised-controlled-trial-of-a-multifaceted-podiatry-intervention-for-the-prevention-of-falls-in-older-people-the-reform-trial
#14
Sarah Cockayne, Joy Adamson, Arabella Clarke, Belen Corbacho, Caroline Fairhurst, Lorraine Green, Catherine E Hewitt, Kate Hicks, Anne-Maree Kenan, Sarah E Lamb, Caroline McIntosh, Hylton B Menz, Anthony C Redmond, Zoe Richardson, Sara Rodgers, Wesley Vernon, Judith Watson, David J Torgerson
BACKGROUND: Falls are a major cause of morbidity among older people. A multifaceted podiatry intervention may reduce the risk of falling. This study evaluated such an intervention. DESIGN: Pragmatic cohort randomised controlled trial in England and Ireland. 1010 participants were randomised (493 to the Intervention group and 517 to Usual Care) to either: a podiatry intervention, including foot and ankle exercises, foot orthoses and, if required, new footwear, and a falls prevention leaflet or usual podiatry treatment plus a falls prevention leaflet...
2017: PloS One
https://www.readbyqxmd.com/read/28107371/sexual-reproductive-health-needs-and-rights-of-young-people-in-slum-areas-of-kampala-uganda-a-cross-sectional-study
#15
Andre M N Renzaho, Joseph K Kamara, Nichole Georgeou, Gilbert Kamanga
BACKGROUND: Young people in Uganda face various sexual and reproductive health risks, especially those living in urban slums. The aim of this study was to examine factors associated with comprehensive categories of sexual and reproductive health, including sexual behaviours; sexual education and access to contraceptive services; family planning; prevention of STDs; sexual consent as a right; gender based violence; as well as HIV testing, counselling, disclosure and support. METHODS: The study was cross-sectional in design and was carried out in July 2014 in Makindye and Nakawa Divisions of Kampala City, Uganda...
2017: PloS One
https://www.readbyqxmd.com/read/28107352/coping-well-with-advanced-cancer-a-serial-qualitative-interview-study-with-patients-and-family-carers
#16
Catherine Walshe, Diane Roberts, Lynda Appleton, Lynn Calman, Paul Large, Mari Lloyd-Williams, Gunn Grande
OBJECTIVES: To understand successful strategies used by people to cope well when living with advanced cancer; to explore how professionals can support effective coping strategies; to understand how to support development of effective coping strategies for patients and family carers. DESIGN: Qualitative serial (4-12 week intervals) interview study with people with advanced cancer and their informal carers followed by focus groups. The iterative design had a novel focus on positive coping strategies...
2017: PloS One
https://www.readbyqxmd.com/read/28107321/the-intersection-of-palliative-care-and-survivorship%C3%A2
#17
Lisa Kennedy Sheldon
People who are diagnosed with cancer become our patients, but, by some definitions, they also qualify as cancer survivors and people who may need palliative care. This may be confusing for patients with cancer and for those who define care by oncology setting or specialty. It may be helpful to test these concepts using case studies.
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February 1, 2017: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28107221/cash-vs-food-assistance-to-improve-adherence-to-antiretroviral-therapy-among-hiv-infected-adults-in-tanzania-a-randomized-trial
#18
Sandra I McCoy, Prosper F Njau, Carolyn Fahey, Ntuli Kapologwe, Suneetha Kadiyala, Nicholas P Jewell, William H Dow, Nancy S Padian
OBJECTIVE: We evaluated the effectiveness of short-term cash and food assistance to improve adherence to antiretroviral therapy (ART) and retention in care among people living with HIV in Tanzania. METHODS: At three clinics, 805 participants were randomized to three groups in a 3 : 3 : 1 ratio, stratified by site : nutrition assessment and counseling (NAC) and cash transfers (∼$11/month, n = 347), NAC and food baskets (n = 345), and NAC-only (comparison group, n = 113, clinicaltrials...
January 19, 2017: AIDS
https://www.readbyqxmd.com/read/28107174/biological-bases-of-human-musicality
#19
Carla Perrone-Capano, Floriana Volpicelli, Umberto di Porzio
Music is a universal language, present in all human societies. It pervades the lives of most human beings and can recall memories and feelings of the past, can exert positive effects on our mood, can be strongly evocative and ignite intense emotions, and can establish or strengthen social bonds. In this review, we summarize the research and recent progress on the origins and neural substrates of human musicality as well as the changes in brain plasticity elicited by listening or performing music. Indeed, music improves performance in a number of cognitive tasks and may have beneficial effects on diseased brains...
January 20, 2017: Reviews in the Neurosciences
https://www.readbyqxmd.com/read/28107107/title-tobacco-alcohol-and-drug-use-of-people-with-mood-and-anxiety-disorders-differential-impact-of-family-and-friends
#20
Eunji Nam, Sadaaki Fukui
OBJECTIVE: Substance use among people with mood and anxiety disorders is highly prevalent. The literature suggests that substance use among people with mood and anxiety disorders is linked to social relational factors, yet it has been rarely the case that studies explicitly examine the differential impact of family and friends. This study investigated the association between family relationships, friendships, and substance use among people with mood and anxiety disorders. METHODS: Using the National Survey of American Life, structural equation modeling tested the unique effects of family relationships and friendships on tobacco, alcohol, and drug use (n = 1,076)...
January 20, 2017: Journal of Dual Diagnosis
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