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Urologic oncology

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https://www.readbyqxmd.com/read/28418091/newsworthiness-versus-scientific-impact-are-the-most-highly-cited-urology-papers-the-most-widely-disseminated-in-the-media
#1
E M O'Connor, G J Nason, F O'Kelly, R P Manecksha, S Loeb
BACKGROUND: Discordance exists between scientific impact and media attention. Altmetrics are non-traditional measures of impact which are composite scores that include social media and traditional media sharing of an article. OBJECTIVE: To assess whether a correlation exists between newsworthiness (Altmetric score) and the scientific impact markers such as citation analysis, impact factors and levels of evidence. MATERIALS AND METHODS: The top 5 most cited articles for the year 2014 and 2015 from the top 10 ranking urology journals (scientific impact group) were identified...
April 18, 2017: BJU International
https://www.readbyqxmd.com/read/28411911/risk-assessment-in-small-renal-masses-a-review-article
#2
REVIEW
Maxine Sun, Malte Vetterlein, Lauren C Harshman, Steven L Chang, Toni K Choueiri, Quoc-Dien Trinh
The incidence of localized renal cell carcinoma (RCC) has been steadily increasing, in large part because of the increased use of imaging. Optimizing the management of localized RCC has become one of the leading priorities and foremost challenges within the urologic-oncologic community. Adequate risk stratification of patients following the diagnosis of localized RCC has become meaningful in deciding whether to treat, how to treat, and how intensively to treat. This article characterizes the existing risk assessment models that can be useful as treatment decision aids for patients with localized RCC...
May 2017: Urologic Clinics of North America
https://www.readbyqxmd.com/read/28409220/pet-and-pet-ct-with-radiolabeled-choline-in-prostate-cancer-a-critical-reappraisal-of-20-years-of-clinical-studies
#3
REVIEW
Giampiero Giovacchini, Elisabetta Giovannini, Rossella Leoncini, Mattia Riondato, Andrea Ciarmiello
We here aim to provide a comprehensive and critical review of the literature concerning the clinical applications of positron emission tomography/computed tomography (PET/CT) with radiolabeled choline in patients with prostate cancer (PCa). We will initially briefly summarize the historical context that brought to the synthesis of [(11)C]choline, which occurred exactly 20 years ago. We have arbitrarily grouped the clinical studies in three different periods, according to the year in which they were published and according to their relation with their applications in urology, radiotherapy and oncology...
April 14, 2017: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/28399840/a-multicentre-randomised-controlled-trial-to-evaluate-the-efficacy-morbidity-and-functional-outcome-of-endoscopic-transanal-proctectomy-versus-laparoscopic-proctectomy-for-low-lying-rectal-cancer-etap-greccar-11-trial-rationale-and-design
#4
Bernard Lelong, Cécile de Chaisemartin, Helene Meillat, Sandra Cournier, Jean Marie Boher, Dominique Genre, Mehdi Karoui, Jean Jacques Tuech, Jean Robert Delpero
BACKGROUND: Total mesorectal excision is the standard surgical treatment for mid- and low-rectal cancer. Laparoscopy represents a clear leap forward in the management of rectal cancer patients, offering significant improvements in post-operative measures such as pain, first bowel movement, and hospital length of stay. However, there are still some limits to its applications, especially in difficult cases. Such cases may entail either conversion to an open procedure or positive resection margins...
April 11, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28399699/prognostic-and-discriminative-power-of-the-7th-tnm-classification-for-patients-with-surgically-treated-papillary-renal-cell-carcinoma-results-of-a-multi-institutional-validation-study-corona-subtype-project
#5
Matthias May, Cristian Surcel, Umberto Capitanio, Paolo Dell'Oglio, Tobias Klatte, Shahrokh Shariat, Thorsten Ecke, Ingmar Wolff, Daniel Vergho, Nina Wagener, Nina Huck, Sascha Pahernik, Stefan Zastrow, Manfred Wirth, Hendrik Borgmann, Axel Haferkamp, Mireia Musquera, Laura M Krabbe, Edwin Herrmann, Anna Scavuzzo, Cristian Mirvald, Georg Hutterer, Richard Zigeuner, Christian G Stief, Raphaela Waidelich, Luca Cindolo, Krystina Kalusova, Sabine D Brookman-May
OBJECTIVE: Studies on the prognostic reliability of the Union for International Cancer Control tumor, node, metastasis (TNM) staging system for renal cell carcinoma (RCC) predominantly focus on clear-cell RCC. Therefore, the aim of this study was to investigate whether the oncological prognosis of surgically treated papillary RCC (papRCC) patients is reliably given by the current TNM system, by analyzing the largest database reported to date. MATERIALS AND METHODS: Data on 2325 papRCC patients who underwent surgical treatment in 1984- 2015 were collated from 17 international centers (median follow-up 47 months)...
April 12, 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28396184/focal-laser-ablation-of-prostate-cancer-feasibility-of-mri-us-fusion-for-guidance
#6
Shyam Natarajan, Tonye A Jones, Alan M Priester, Rory Geoghegan, Patricia Lieu, Merdie Delfin, Ely Felker, Daniel J A Margolis, Anthony Sisk, Allan Pantuck, Warren Grundfest, Leonard S Marks
PURPOSE: Focal laser ablation (FLA) is a potential treatment for some men with prostate cancer (CaP). As currently practiced, FLA is performed by radiologists in a MRI unit (in-bore). We evaluated the safety and feasibility of performing FLA in a urology clinic (out-of-bore), using magnetic resonance imaging-ultrasound (MRI/US) fusion for guidance. MATERIALS AND METHODS: 11 men with intermediate risk CaP were enrolled in this prospective, IRB-approved pilot study...
April 7, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28355119/high-intensity-focused-ultrasound-for-the-treatment-of-prostate-cancer-a-review
#7
Christian G Chaussy, Stefan Thüroff
Over the past 25 years, the average life expectancy for men has increased almost 4 years, and the age of prostate cancer detection has decreased an average of 10 years with diagnosis increasingly made at early-stage disease where curative therapy is possible. These changing trends in the age and extent of malignancy at diagnosis have revealed limitations in conventional curative therapies for prostate cancer, including a significant risk of aggressive cancer recurrence, and the risk of long-term genitourinary morbidity and its detrimental impact on patient's quality of life (QOL)...
April 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28342659/urologic-oncologic-surveyrobotic-level-iii-inferior-vena-cava-tumor-thrombectomy-initial-series-gill-is-metcalfe-c-abreu-a-duddalwar-v-chopra-s-cunningham-m-thangathurai-d-ukimura-o-satkunasivam-r-hung-a-papalia-r-aron-m-desai-m-gallucci-m-j-urol-2015-oct-194
#8
Max Meng
PURPOSE: Level III inferior vena cava tumor thrombectomy for renal cancer is one of the most challenging open urologic surgeries. We present the initial series of completely intracorporeal robotic level III inferior vena cava tumor thrombectomy. MATERIALS AND METHODS: Nine patients underwent robotic level III inferior vena cava thrombectomy and 7 patients underwent level II thrombectomy. The entire operation (high intrahepatic inferior vena cava control, caval exclusion, tumor thrombectomy, inferior vena cava repair, radical nephrectomy, and retroperitoneal lymphadenectomy) was performed exclusively robotically...
March 22, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28336286/robotic-surgery-in-uro-oncology-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#9
REVIEW
Daniel Steffens, Ruban Thanigasalam, Scott Leslie, Bharvi Maneck, Jane M Young, Michael Solomon
Robotic surgery represents a new horizon in minimally-invasive urological surgery. This systematic review of the literature and meta-analysis examines the effectiveness of robotic surgery compared with laparoscopic or open surgery for major uro-oncological procedures. 25 articles reported findings from 8 trials of prostatectomy (4 trials) and cystectomy (4 trials) including 1033 participants. Robotic surgery is comparable to laparoscopic or open surgery for oncological outcomes, overall complications, and provides somewhat better functional outcome, when compared to laparoscopic and open surgery...
March 20, 2017: Urology
https://www.readbyqxmd.com/read/28336202/medical-surgical-activity-and-the-current-state-of-training-of-urology-residents-in-spain-results-of-a-national-survey
#10
M E Rodríguez-Socarrás, J Gómez Rivas, M García-Sanz, L Pesquera, L Tortolero-Blanco, M Ciappara, A Melnick, J Colombo, G Patruno, Á Serrano-Pascual, J Bachiller-Burgos, J M Cozar-Olmo
OBJECTIVES: To determine the actual state of medical-surgical activity and training for urology residents in Spain. MATERIAL AND METHOD: We designed 2 anonymous surveys, which were uploaded with the Google Docs(©) tool so that the respondents could answer the surveys online. The online collection period was September 2015 to January 2016. The collected data were processing using the statistical programme IBM SPSS for Windows, Version 21.0 and the programme R version 3...
March 20, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28326796/surgical-treatment-of-4-10%C3%A2-cm-renal-cell-carcinoma-a-survey-of-the-lions-and-gazelles
#11
Sara L Best, Michael Blute, Brian Lane, E Jason Abel
INTRODUCTION: The decision between partial nephrectomy (PN) and radical nephrectomy (RN) may be influenced by training, practice type, or location. We sought to evaluate current opinions about the optimal management of 4-10 cm renal-cell carcinoma (RCC). MATERIALS AND METHODS: A survey was emailed to ∼2500 Endourologic Society and Society of Urologic Oncology members regarding training, practice setting, and interest in clinical trials in addition to questions about four patient scenarios...
April 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28316997/sildenafil-can-affect-innate-and-adaptive-immune-system-in-both-experimental-animals-and-patients
#12
REVIEW
Monika Kniotek, Agnieszka Boguska
Sildenafil, a type 5 phosphodiesterase inhibitor (PDE5-I), is primarily used for treating erectile dysfunction. Sildenafil inhibits the degradation of cyclic guanosine monophosphate (cGMP) by competing with cGMP for binding site of PDE5. cGMP is a secondary messenger activating protein kinases and a common regulator of ion channel conductance, glycogenolysis, and cellular apoptosis. PDE5 inhibitors (PDE-Is) found application in cardiology, nephrology, urology, dermatology, oncology, and gynecology. Positive result of sildenafil treatment is closely connected with its immunomodulatory effects...
2017: Journal of Immunology Research
https://www.readbyqxmd.com/read/28314346/oncologic-imaging-urology
#13
(no author information available yet)
No abstract text is available yet for this article.
March 2017: Anticancer Research
https://www.readbyqxmd.com/read/28279064/cancer-specific-mortality-among-korean-men-with-localized-or-locally-advanced-prostate-cancer-treated-with-radical-prostatectomy-versus-radiotherapy-a-multi-center-study-using-propensity-scoring-and-competing-risk-regression-analyses
#14
Kyo Chul Koo, Jin Seon Cho, Woo Jin Bang, Seung Hwan Lee, Sung Yong Cho, Sun Il Kim, Se Joong Kim, Koon Ho Rha, Sung Joon Hong, Byung Ha Chung
Purpose: Studies comparing radical prostatectomy (RP) outcomes with those of radiotherapy with or without androgen deprivation therapy (RT±ADT) for prostate cancer (PCa) have yielded conflicting results. Therefore, we used propensity score-matched analysis and competing risk regression analysis to compare cancer-specific mortality (CSM) and other-cause mortality (OCM) between these two treatments. Materials and Methods: The multi-center, Severance Urological Oncology Group registry was utilized to identify 3,028 patients with clinically localized or locally advanced PCa treated by RP (n=2,521) or RT±ADT (n=507) between 2000 and 2016...
March 8, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28267605/chairmen-in-academic-urologic-practice-a-descriptive-analysis
#15
Nicholas J Farber, Brian J Friel, Young S Kwon, Andrew Cruz, Sammy E Elsamra
OBJECTIVE: To examine and characterize the demographics and scholarly characteristics of academic urology chairmen at the time of appointment. MATERIALS AND METHODS: The chairman of each United States urology residency program as of September 2016 was included in the study. Interim chairmen, as well as programs for which no clearly defined chair could be identified, were excluded. Demographic and academic data were collected via publically available curriculum vitae, departmental websites, Google search engine, and PubMed and Scopus websites...
March 4, 2017: Urology
https://www.readbyqxmd.com/read/28263130/improving-prostate-cancer-care-collaboratively-a-multidisciplinary-formal-consensus-based-approach
#16
Andrew Loblaw, Jack Barkin, Roger Buckley, Hans Chung, John Kell, Rajiv Singal, Jeff Spodek, Danny Vesprini, Stanley Flax
INTRODUCTION: There are numerous standard treatment options for men diagnosed with localized prostate cancer. Multidisciplinary consultation before decision-making is a consensus- and quality-based objective in Ontario. With the goals of working together more collaboratively and to provide higher quality information for patients at the time of decision-making, a prostate cancer community partnership consensus (PCPC) panel was formed among six partnering centers in the Greater Toronto Area...
February 2017: Canadian Journal of Urology
https://www.readbyqxmd.com/read/28254473/precision-surgery-and-genitourinary-cancers
#17
R Autorino, F Porpiglia, P Dasgupta, J Rassweiler, J W Catto, L J Hampton, E Lima, V Mirone, I H Derweesh, F M J Debruyne
The landscape of the surgical management of urologic malignancies has dramatically changed over the past 20 years. On one side, better diagnostic and prognostic tools allowed better patient selection and more reliable surgical planning. On the other hand, the implementation of minimally invasive techniques and technologies, such as robot-assisted laparoscopy surgery and image-guided surgery, allowed minimizing surgical morbidity. Ultimately, these advances have translated into a more tailored approach to the management of urologic cancer patients...
February 20, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28247670/-micrornas-as-potential-noninvasive-markers-in-the-diagnosis-of-urological-malignancies
#18
I R Gilyazova, E A Klimentova, V N Pavlov, E K Khusnutdinova
Small non-coding RNAs (microRNAs) are involved in almost all biological mechanisms of carcinogenesis. Due to their stability in biological fluids microRNAs may serve a perspective biomarker for diagnosis and prognosis of oncological diseases. The review is dedicated to the analysis of microRNAs, as potential diagnostic markers of urological malignancies. Recent advances in the knowledge of miRNAs origin in body fluids, their stability and application as a potentially new class of biomarkers in medicine are summarized and discussed in the article...
April 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28237495/prostate-cancer-before-renal-transplantation-a-multicentre-study
#19
C Chahwan, A Doerfler, N Brichart, S Bouyé, T Culty, C Iselin, C Pfister, F Sallusto, L Salomon, G Verhoest, L Viart, X Tillou
INTRODUCTION: The surgical issues of renal transplantation (RT) after localized prostate cancer (PC) treatment and oncological outcomes after transplantation in patients on the waiting list with a history of PC were unknown. We conducted a retrospective multicentre study including all patients with PC diagnosed before the kidney transplantation. METHODS: Fifty-two patients were included from December 1993 to December 2015. The median age at diagnosis of PC was 59...
March 2017: Progrès en Urologie
https://www.readbyqxmd.com/read/28237000/dose-estimation-in-pediatric-nuclear-medicine
#20
REVIEW
Frederic H Fahey, Alison B Goodkind, Donika Plyku, Kitiwat Khamwan, Shannon E O'Reilly, Xinhua Cao, Eric C Frey, Ye Li, Wesley E Bolch, George Sgouros, S Ted Treves
The practice of nuclear medicine in children is well established for imaging practically all physiologic systems but particularly in the fields of oncology, neurology, urology, and orthopedics. Pediatric nuclear medicine yields images of physiologic and molecular processes that can provide essential diagnostic information to the clinician. However, nuclear medicine involves the administration of radiopharmaceuticals that expose the patient to ionizing radiation and children are thought to be at a higher risk for adverse effects from radiation exposure than adults...
March 2017: Seminars in Nuclear Medicine
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