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https://www.readbyqxmd.com/read/29772990/the-effects-of-meniscal-geometry-on-susceptibility-for-meniscal-and-acl-injury-in-non-arthritic-knees-a-retrospective-case-control-study
#1
Alexander Tejani, Qais Naziri, Preston W Grieco, Robert Pivec, Damon Greene, Bhaveen V Kapadia, Dipal Chatterjee, William P Urban
Prior studies have not found significant differences in meniscal parameters between patients with meniscal and ligamentous injury and those without. The purpose of this study was to determine whether such relationships exist. Clinical records and magnetic resonance images of three subject groups were reviewed. Group 1 solely had meniscal tears (medial/lateral), Group 2 had meniscal tears with concurrent ACL tears, and Group 3 had healthy knees. The mean age of subjects included was 35.9 years (range 8.2-72...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29770844/effect-of-arthroscopic-resection-for-discoid-lateral-meniscus-on-the-axial-alignment-of-the-lower-limb
#2
Puyan Zhang, Qichun Zhao, Xifu Shang, Yingming Wang
PURPOSE: This study was designed to investigate the changes in the lower limb axial alignment and knee joint function after arthroscopic resection of discoid lateral menisci. METHODS: Pre-operative and post-operative full-length weight-bearing radiographs of the lower limb were obtained from 60 patients with discoid lateral menisci from August 2015 to August 2016. Twenty-four patients were treated with meniscectomy and 36 cases were treated with meniscoplasty. The axial alignment of the lower limb was measured, and changes in the lower limb axial alignment before and after surgery were analyzed...
May 16, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29770332/incidence-and-extent-of-graft-extrusion-following-meniscus-allograft-transplantation
#3
REVIEW
Dae-Hee Lee
Background: The incidence and extent of graft extrusion after meniscus allograft transplantation (MAT) may differ in patients undergoing medial and lateral meniscus transplantation due to the use of different surgical techniques. This meta-analysis was therefore designed to quantify the extent and incidence of graft extrusion after meniscus allograft transplantation. Methods: Following preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines, all studies reporting absolute extrusion, relative percentage of extrusion (RPE), or frequency of major extrusions (>3 mm) on magnetic resonance imaging in patients undergoing medial or lateral MAT were included...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29754495/evaluation-of-anterior-intermeniscal-ligament-in-discoid-lateral-meniscus-cases-and-presenting-the-accompanying-meniscal-pathologies-with-mri
#4
Ali Koç, Turgut Tursem Tokmak, Özgür Karabıyık, Gamze Türk
Background Although several studies were conducted to put forth the biomechanical function of anterior intermeniscal ligament (AIML) on the stability of meniscal structures, there are few data on the etiology of the early degeneration of discoid type compared to the normal shaped ones. Purpose To determine the AIML subtypes and accompanying meniscal pathologies in discoid lateral menisci (DLM) on knee MRI exams. Material and Methods Knee MRI exams of 171 individuals with DLM were reviewed. DLMs and AIMLs were typed according to Watanabe's classification and Nelson-Laprade classification, respectively...
January 1, 2018: Acta Radiologica
https://www.readbyqxmd.com/read/29752501/it-is-safe-and-effective-to-use-all-inside-meniscal-repair-devices-for-posteromedial-meniscal-ramp-lesions
#5
Giles Heilpern, Jo Stephen, Simon Ball, Andrew Amis, Andy Williams
PURPOSE: Recently, it has been recognized that meniscocapsular ('ramp') lesions of the posterior one-third of the medial meniscus frequently occur during injuries causing ACL rupture, and that these lesions are easily missed at arthroscopy. Furthermore, it is clear that these lesions are biomechanically significant, adding to the deficits caused by ACL rupture, and that their repair can reverse this. The efficacy of an all inside repair technique has been questioned by some authors and by those who advocate a suture shuttle technique via an accessory posteromedial portal...
May 12, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29752053/anterior-laxity-lateral-tibial-slope-and-in-situ-acl-force-differentiate-knees-exhibiting-distinct-patterns-of-motion-during-a-pivoting-event-a-human-cadaveric-study
#6
Robert N Kent, Mark J Amirtharaj, Brendan M Hardy, Andrew D Pearle, Thomas L Wickiewicz, Carl W Imhauser
Knee instability following anterior cruciate ligament (ACL) rupture compromises function and increases risk of injury to the cartilage and menisci. To understand the biomechanical function of the ACL, previous studies have primarily reported the net change in tibial position in response to multiplanar torques, which generate knee instability. In contrast, we retrospectively analyzed a cohort of 13 consecutively tested cadaveric knees and found distinct motion patterns, defined as the motion of the tibia as it translates and rotates from its unloaded, initial position to its loaded, final position...
April 11, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29744321/morphology-of-intra-articular-structures-and-histology-of-menisci-of-knee-joint
#7
Monika Gupta, Parmod Kumar Goyal, Poonam Singh, Anu Sharma
Introduction: Menisci and cruciate ligaments are intra-articular structures of knee, and injury to these structures is common. Morphometric data gained in the study will help in analyzing the variations among humans and correlating it with the possibility, location, and type of injuries as well as better interpretation of structures during magnetic resonance imaging and arthroscopy which will further help in reconstructive surgeries of knee. Materials and Methods: Width and thickness of the medial menisci (MM), lateral menisci (LM), and maximum length and width of anterior cruciate ligament (ACL) and posterior cruciate ligament (PCL) were taken on twenty knees...
April 2018: International Journal of Applied and Basic Medical Research
https://www.readbyqxmd.com/read/29713636/the-pathobiology-of-the-meniscus-a-comparison-between-the-human-and-dog
#8
REVIEW
Olga Krupkova, Lucas Smolders, Karin Wuertz-Kozak, James Cook, Antonio Pozzi
Serious knee pain and related disability have an annual prevalence of approximately 25% on those over the age of 55 years. As curative treatments for the common knee problems are not available to date, knee pathologies typically progress and often lead to osteoarthritis (OA). While the roles that the meniscus plays in knee biomechanics are well characterized, biological mechanisms underlying meniscus pathophysiology and roles in knee pain and OA progression are not fully clear. Experimental treatments for knee disorders that are successful in animal models often produce unsatisfactory results in humans due to species differences or the inability to fully replicate disease progression in experimental animals...
2018: Frontiers in Veterinary Science
https://www.readbyqxmd.com/read/29705348/proteoglycans-contribute-locally-to-swelling-but-globally-to-compressive-mechanics-in-intact-cervine-medial-meniscus
#9
Arthur J Michalek, Laurel Kuxhaus, Daniel Jaremczuk, Nicole L Zaino
Loss of charged proteoglycans in the knee meniscus, which aid in the support of compressive loads by entraining water, is an effect of degeneration and is often associated with osteoarthritis. In healthy menisci, proteoglycan content is highest in the inner white zone and decreases towards the peripheral red zone. We hypothesized that loss of proteoglycans would reduce both osmotic swelling and compressive stiffness, spatially localized to the avascular white zone of the meniscus. This hypothesis was tested by targeted enzymatic digestion of proteoglycans using hyaluronidase in intact cervine medial menisci...
April 24, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29705172/the-effect-of-arch-drop-on-tibial-rotation-and-tibiofemoral-contact-stress-in-postpartum-women
#10
Kaitlin Rabe, Neil A Segal, Saphia Waheed, Donald D Anderson
BACKGROUND: Women are at higher risk for knee osteoarthritis and numerous other lower limb musculoskeletal disorders. Arch drop during pregnancy and the resultant excessive pronation of the feet may alter loading patterns and contribute to the higher prevalence of knee osteoarthritis in women. OBJECTIVE: To determine the effect of arch drop on tibial rotation and tibiofemoral contact stress. DESIGN: Interventional study with internal control SETTING: Biomechanics laboratory PARTICIPANTS: Eleven postpartum women (age 33...
April 26, 2018: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/29694226/modified-kelvin-equations-for-capillary-condensation-in-narrow-and-wide-grooves
#11
Alexandr Malijevský, Andrew O Parry
We consider the location and order of capillary condensation transitions occurring in deep grooves of width L and depth D. For walls that are completely wet by liquid (contact angle θ=0) the transition is continuous and its location is not sensitive to the depth of the groove. However, for walls that are partially wet by liquid, where the transition is first order, we show that the pressure at which it occurs is determined by a modified Kelvin equation characterized by an edge contact angle θ_{E} describing the shape of the meniscus formed at the top of the groove...
March 30, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29685524/medial-meniscal-extrusion-detection-evaluation-and-clinical-implications
#12
REVIEW
Nayanatara Swamy, Vibhor Wadhwa, Gitanjali Bajaj, Avneesh Chhabra, Tarun Pandey
The menisci play an important role in knee kinematics. Their unique anatomy allows them to channel forces generated during knee movements through the larger tibio-femoral condylar surfaces while simultaneously resisting deleterious hoop stresses. Although physiologic meniscal extrusion occurs with every knee joint movement, pathologic meniscal extrusion subjects the knee to persistent and excessive load transmission. This renders the knee structures susceptible to injury or exacerbates worsening of existing knee joint internal derangement...
May 2018: European Journal of Radiology
https://www.readbyqxmd.com/read/29682310/rehabilitation-following-meniscal-repair-a-systematic-review
#13
Robert C Spang Iii, Michael C Nasr, Amin Mohamadi, Joseph P DeAngelis, Ara Nazarian, Arun J Ramappa
Objective: To review existing biomechanical and clinical evidence regarding postoperative weight-bearing and range of motion restrictions for patients following meniscal repair surgery. Methods and data sources: Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline, we searched MEDLINE using following search strategy: (((("Weight-Bearing/physiology"[Mesh]) OR "Range of Motion, Articular"[Mesh]) OR "Rehabilitation"[Mesh])) AND ("Menisci, Tibial"[Mesh])...
2018: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29679117/the-infrapatellar-fat-pad-is-a-dynamic-and-mobile-structure-which-deforms-during-knee-motion-and-has-proximal-extensions-which-wrap-around-the-patella
#14
Joanna M Stephen, Ran Sopher, Sebastian Tullie, Andrew A Amis, Simon Ball, Andy Williams
PURPOSE: The infrapatellar fat pad (IFP) is a common cause of knee pain and loss of knee flexion and extension. However, its anatomy and behavior are not consistently defined. METHODS: Thirty-six unpaired fresh frozen knees (median age 34 years, range 21-68) were dissected, and IFP attachments and volume measured. The rectus femoris was elevated, suprapatellar pouch opened and videos recorded looking inferiorly along the femoral shaft at the IFP as the knee was flexed...
April 20, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29675769/cellular-and-molecular-meniscal-changes-in-the-degenerative-knee-a-review
#15
REVIEW
Mariano López-Franco, Enrique Gómez-Barrena
BACKGROUND: The important role of knee menisci to maintain adequate knee function is frequently impaired since early stages of knee joint degeneration. A better understanding of meniscal impairment may help the orthopaedic surgeon to orient the treatment of the degenerative knee. This review focuses on changes in meniscal cells and matrix when degeneration is in progress. MAIN BODY: Differences in the meniscal structure and metabolism have been investigated in the degenerative knee, both in experimental animal models and in surgical specimens...
April 19, 2018: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/29665801/an-extended-opensim-knee-model-for-analysis-of-strains-of-connective-tissues
#16
M Marieswaran, Arnab Sikidar, Anu Goel, Deepak Joshi, Dinesh Kalyanasundaram
BACKGROUND: OpenSim musculoskeletal models provide an accurate simulation environment that eases limitations of in vivo and in vitro studies. In this work, a biomechanical knee model was formulated with femoral articular cartilages and menisci along with 25 connective tissue bundles representing ligaments and capsules. The strain patterns of the connective tissues in the presence of femoral articular cartilage and menisci in the OpenSim knee model was probed in a first of its kind study...
April 17, 2018: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29658360/hyaluronic-acid-promotes-proliferation-and-migration-of-human-meniscus-cells-via-a-cd44-dependent-mechanism
#17
Tomohiko Murakami, Shuhei Otsuki, Yoshinori Okamoto, Kosuke Nakagawa, Hitoshi Wakama, Nobuhiro Okuno, Masashi Neo
PURPOSE: Treatment of meniscal injury is important for osteoarthritis (OA) prevention. Meniscus cells are divided between inner and outer cells, which have different characteristics and vascularity. We evaluated the effects of hyaluronic acid (HA) on the proliferation and migration of human inner and outer meniscus cells, and investigated the underlying healing mechanisms. MATERIALS AND METHODS: Lateral menisci from 18 patients who underwent total knee arthroplasty were used...
April 15, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29624738/meniscal-extrusion-and-degeneration-during-the-course-of-osteoarthritis-in-the-murine-collagenase-induced-osteoarthritis-model
#18
Lizette Utomo, Susanne M Eijgenraam, Duncan E Meuffels, Sita M A Bierma-Zeinstra, Yvonne M Bastiaansen-Jenniskens, Gerjo J V M van Osch
Meniscal damage is, despite its major role in knee osteoarthritis (OA), often neglected in OA animal models. We evaluated structural meniscal degeneration during the course of OA in the murine collagenase-induced OA (CIOA) model. To investigate this, OA was induced in the knee joints of 33 male C57BL/6 mice by an intra-articular injection of 10U collagenase. The mice were sacrificed after 1, 3, 7, 14, 28, and 56 days, and the knees were harvested and processed for histological analysis. As control, six knees were obtained from 16-week-old mice in which no OA was induced...
April 6, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29618652/the-metalloproteinase-proteoglycans-adamts7-and-adamts12-provide-an-innate-tendon-specific-protective-mechanism-against-heterotopic-ossification
#19
Timothy J Mead, Daniel R McCulloch, Jason C Ho, Yaoyao Du, Sheila M Adams, David E Birk, Suneel S Apte
Heterotopic ossification (HO) is a significant clinical problem with incompletely resolved mechanisms. Here, the secreted metalloproteinases ADAMTS7 and ADAMTS12 are shown to comprise a unique proteoglycan class that protects against a tendency toward HO in mouse hindlimb tendons, menisci, and ligaments. Adamts7 and Adamts12 mRNAs were sparsely expressed in murine forelimbs but strongly coexpressed in hindlimb tendons, skeletal muscle, ligaments, and meniscal fibrocartilage. Adamts7-/- Adamts12-/- mice, but not corresponding single-gene mutants, which demonstrated compensatory upregulation of the intact homolog mRNA, developed progressive HO in these tissues after 4 months of age...
April 5, 2018: JCI Insight
https://www.readbyqxmd.com/read/29606846/double-sided-design-of-electrodes-driving-tunable-dielectrophoretic-miniature-lens
#20
Yousuf Almoallem, Hongrui Jiang
We demonstrate the design methodology, geometrical analysis, device fabrication, and testing of a double-sided design (DSD) of tunable-focus dielectrophoretic liquid miniature lenses. This design is intended to reduce the driving voltage for tuning the lens, utilizing a double-sided electrode design that enhances the electric field magnitude. Fabricated devices were tested and measurements on a goniometer showed changes of up to 14° in the contact angle when the dielectrophoretic force was applied under 25 Vrms ...
October 2017: Journal of Microelectromechanical Systems
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