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total gastrectomy gastric cancer

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https://www.readbyqxmd.com/read/27903746/intestinal-glycolysis-visualized-by-fdg-pet-ct-correlates-with-glucose-decrement-after-gastrectomy
#1
Cheol Ryong Ku, Narae Lee, Jae Won Hong, In Gyu Kwon, Woo Jin Hyung, Sung Hoon Noh, Eun Jig Lee, Mijin Yun, Arthur Cho
Gastrectomy method is known to influence glucose homeostasis. (18)F-fluorodeoxyglucose (FDG) PET/CT acquired after gastrectomy often reveals newly developed physiologic small bowel uptake. We correlated newly developed small bowel FDG uptake and glucose homeostasis in post-gastrectomy gastric cancer patients. We retrospectively analyzed 239 non-diabetic patients who underwent staging and follow-up FDG PET/CT before and after gastrectomy for gastric cancer. Post-operative small bowel glycolysis was quantified by recording intestinal total lesion glycolysis (TLG)...
November 30, 2016: Diabetes
https://www.readbyqxmd.com/read/27896408/is-routine-prophylactic-cholecystectomy-necessary-during-gastrectomy-for-gastric-cancer
#2
Jun Kimura, Chikara Kunisaki, Ryo Takagawa, Hirochika Makino, Michio Ueda, Mitsuyoshi Ota, Mari Oba, Takashi Kosaka, Hirotoshi Akiyama, Itaru Endo
BACKGROUND: Performing routine prophylactic cholecystectomy during gastrectomy in gastric cancer patients has been controversial. The frequency of cholelithiasis, cholecystitis, and cholangitis after gastrectomy has not been reported for large patient populations, so we carried out this retrospective study to aid the assessment of the necessity for prophylactic cholecystectomy. METHODS: This retrospective study reviewed 969 patients with gastric cancer who underwent distal gastrectomies with Billroth I reconstructions (DG) or total gastrectomies with Roux-en-Y reconstructions (TG), preserving the gallbladder, between January 2000 and May 2012...
November 28, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27885538/multi-institutional-prospective-feasibility-study-to-explore-tolerability-and-efficacy-of-oral-nutritional-supplements-for-patients-with-gastric-cancer-undergoing-gastrectomy-ccog1301
#3
Daisuke Kobayashi, Kiyoshi Ishigure, Yoshinari Mochizuki, Hiroshi Nakayama, Mitsuru Sakai, Seiji Ito, Hiroshi Kojima, Masaki Kajikawa, Masahiko Ando, Yasuhiro Kodera
BACKGROUND: Postoperative malnutrition after gastrectomy is deemed inevitable, which could have prejudicial influence on survival for gastric cancer patients. A prospective feasibility study was conducted to evaluate the efficacy of postoperative oral nutritional supplements. METHODS: Stage I-III gastric cancer patients who underwent distal or total gastrectomy received oral administration of Racol(®) NF (Otsuka Pharmaceutical Factory, Japan), a liquid enteral nutritional formula, as a supplement to regular meals...
November 24, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27869493/laparoscopy-assisted-gastrectomy-in-the-elderly-experience-from-a-uk-centre
#4
A Tandon, I Rajendran, M Aziz, R Kolamunnage-Dona, Q M Nunes, M Shrotri
BACKGROUND Gastric cancer has a high incidence in the elderly in the UK, with a significant number of patients aged 75 years or more. While surgery forms the mainstay of treatment, evidence pertaining to the management of gastric cancer in the Western population in this age group is scarce. METHODS We retrospectively reviewed the outcomes of laparoscopy-assisted total and distal gastrectomies at our centre from 2005 to 2015. Patients aged 70 years or above were included in the elderly group. RESULTS A total of 60 patients underwent laparoscopy-assisted gastrectomy over a 10-year period, with a predominance of male patients...
November 21, 2016: Annals of the Royal College of Surgeons of England
https://www.readbyqxmd.com/read/27863481/association-of-nutritional-status-related-indices-and-chemotherapy-induced-adverse-events-in-gastric-cancer-patients
#5
Seung Hee Seo, Sung-Eun Kim, Yoon-Koo Kang, Baek-Yeol Ryoo, Min-Hee Ryu, Jae Ho Jeong, Shin Sook Kang, Mihi Yang, Jung Eun Lee, Mi-Kyung Sung
BACKGROUND: Malnutrition in gastrectomized patients receiving chemotherapy is associated with the susceptibility to chemotherapy-related adverse events. This study evaluated pre-operative nutritional status-related indices associated with adverse events in post-operation gastric cancer patients receiving chemotherapy. METHODS: Medical records of 234 gastrectomized patients under adjuvant tegafur/gimeracil/oteracil chemotherapy with extended lymph node dissection were analyzed...
November 18, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27853375/total-versus-subtotal-gastrectomy-for-distal-gastric-cancer-meta-analysis-of-randomized-clinical-trials
#6
Lingling Kong, Nianzhao Yang, Lianghui Shi, Guohai Zhao, Minghai Wang, Yisheng Zhang
OBJECTIVES: This meta-analysis of randomized controlled trials was conducted to give a more precise estimation of the efficacy and drawbacks of total gastrectomy (TG) versus subtotal gastrectomy (SG) for proven distal gastric cancer. METHODS: The electronic databases Cochrane and PubMed (updated on April 10, 2016) were searched for randomized controlled trials comparing TG with SG as surgical procedures for distal gastric cancer. Five outcome variables were analyzed, including postoperative complications, anastomotic fistula rate, hospital mortality rate, mortality rate of recurrence (the patient's death is caused by the recurrence of gastric cancer, rather than caused by other diseases), and 5-year survival rate...
2016: OncoTargets and Therapy
https://www.readbyqxmd.com/read/27846181/comparison-of-reduced-port-totally-laparoscopic-assisted-total-gastrectomy-duet-tltg-and-conventional-laparoscopic-assisted-total-gastrectomy
#7
Han Byeol Kim, Su Mi Kim, Man Ho Ha, Jeong Eun Seo, Min-Gew Choi, Tae Sung Sohn, Jae Moon Bae, Sung Kim, Jun Ho Lee
BACKGROUND: The aim of this study was to compare surgical outcomes of patients with gastric cancer undergoing reduced port totally laparoscopic-assisted total gastrectomy (duet TLTG) with those of patients undergoing conventional laparoscopic-assisted total gastrectomy (LATG). MATERIALS AND METHODS: Between January 2013 and 2015, 54 patients with gastric cancer underwent LATG at the Samsung Medical Center. Duet TLTG using 3 ports was performed in 30 patients, and conventional LATG using 5 ports was performed in 24 patients...
November 14, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27843732/resection-of-large-metachronous-liver-metastasis-with-gastric-origin-case-report-and-review-of-the-literature
#8
REVIEW
Ionut Negoi, Alexandru Runcanu, Sorin Paun, Ruxandra Irina Negoi, Mircea Beuran
INTRODUCTION: Increasing evidence suggests that surgical resection may be offered to a subgroup of patients with liver metastasis of gastric adenocarcinoma. The aim of this case report is to illustrate the surgical resection of a single liver metachronous recurrence twelve months after a radical total gastrectomy for cancer. CASE REPORT: A 63-year-old male patient with an Eastern Cooperative Oncology Group performance status of 1 was referred to our hospital for a single, large liver metastasis, twelve months after a radical total gastrectomy and DII lymphadenectomy for upper third gastric adenocarcinoma...
October 3, 2016: Curēus
https://www.readbyqxmd.com/read/27837291/the-psychosocial-impact-of-undergoing-prophylactic-total-gastrectomy-ptg-to-manage-the-risk-of-hereditary-diffuse-gastric-cancer-hdgc
#9
Nina Hallowell, Julia Lawton, Shirlene Badger, Sue Richardson, Richard H Hardwick, Carlos Caldas, Rebecca C Fitzgerald
Individuals identified as at high risk of developing Hereditary Diffuse Gastric Cancer (HDGC) are advised to undergo prophylactic surgery - have their stomach removed - in their early twenties. Research with (older) cancer patients who undergo gastrectomy for curative reasons suggests that gastric resection has a number of physical and psychosocial sequelae. Because it is difficult to extrapolate the findings of studies of older cancer patients to younger healthy patients who are considering prophylactic total gastrectomy (PTG), the aim of this qualitative interview study was to determine the psychosocial implications of undergoing prophylactic surgery to manage genetic risk...
November 11, 2016: Journal of Genetic Counseling
https://www.readbyqxmd.com/read/27834031/surgeon-s-experience-overrides-the-effect-of-hospital-volume-for-postoperative-outcomes-of-laparoscopic-surgery-in-gastric-cancer-multi-institutional-study
#10
Han Hong Lee, Sang-Yong Son, Ju Hee Lee, Min Gyu Kim, Hoon Hur, Do Joong Park
BACKGROUND: Hospital volume is known to be a crucial factor in reducing postoperative morbidity and mortality in laparoscopic gastrectomy for gastric cancer. However, it is unclear whether surgeon's individual experience can overcome the effect of hospital volume. METHODS: Clinicopathologic data of initial 50 laparoscopic gastrectomy cases were collected from six gastric cancer surgeons. Half of the six surgeons worked in high-volume centers, and the other half worked in low-volume hospitals...
November 10, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27833389/factors-affecting-the-quality-of-life-of-patients-after-gastrectomy-as-assessed-using-the-newly-developed-pgsas-45-scale-a-nationwide-multi-institutional-study
#11
Koji Nakada, Masazumi Takahashi, Masami Ikeda, Shinichi Kinami, Masashi Yoshida, Yoshikazu Uenosono, Yoshiyuki Kawashima, Sayumi Nakao, Atsushi Oshio, Yoshimi Suzukamo, Masanori Terashima, Yasuhiro Kodera
AIM: To identify certain clinical factors other than the type of gastrectomy which affect the postoperative quality of life (QOL) of patients after gastrectomy. METHODS: The postgastrectomy syndrome assessment scale (PGSAS)-45 was designed to assess the severity of symptoms, the living status and the QOL of gastrectomized patients. It consists of 45 items, of which 22 are original items while 23 were retrieved from the SF-8 and Gastrointestinal Symptoms Rating Scale questionnaires with permission...
October 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27830390/harvest-of-at-least-23-lymph-nodes-is-indispensable-for-stage-n3-gastric-cancer-patients
#12
Gaozan Zheng, Fan Feng, Man Guo, Guanghui Xu, Shushang Liu, Zhen Liu, Li Sun, Liu Hong, Jianjun Yang, Xiao Lian, Daiming Fan, Hongwei Zhang
BACKGROUND: The National Comprehensive Cancer Network (NCCN) recommends that at least 15 lymph nodes (LNs) be removed during radical gastrectomy. This study aims to investigate the optimal number of LNs resected for radical gastrectomy. PATIENTS AND METHODS: From September 2008 to March 2015, a total of 1990 gastric cancer patients were enrolled in this study. Clinicopathological features and survivals were recorded, and the association between the number of LNs resected and the prognosis of gastric cancer were analyzed...
November 9, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27826782/a-novel-method-of-self-pulling-and-latter-transected-reconstruction-in-totally-laparoscopic-total-gastrectomy-feasibility-and-short-term-safety
#13
Jun Hong, Ya-Ping Wang, Jian Wang, Yi-Bing Bei, Lu-Chun Hua, Han-Kun Hao
BACKGROUND: This study depicts a novel reconstruction method of self-pulling and latter transection (SPLT) in totally laparoscopic total gastrectomy (TLTG) and evaluates its feasibility and short-term safety by comparing its surgical and postoperative outcomes with the conventional TLTG. PATIENTS AND METHODS: Forty patients with gastric cancer from June 2014 to December 2015 received SPLT-TLTG. Data of clinicopathologic characteristics, surgical and postoperative outcomes, and follow-up findings in SPLT cases were collected and retrospectively compared with those of conventional TLTG to clarify the clinical benefits...
November 8, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27819638/digestive-decompression-to-prevent-digestive-fistulas-after-gastric-neoplasm-resection
#14
Augustin Marian Marincaş, Virgiliu Mihail Prunoiu, Ciprian Cirimbei, Raluca Buzatu, Rodica Corniciuc, Cristian Sersea, Eugen Brătucu
: Introduction: The risk of digestive fistula in patients operated for gastric neoplasm is increased due to biological imbalances generated by the cancer's progression, by diagnosis in advanced stages, and by the scale of intervention. Under these circumstances the use of some technical means to protect digestive sutures in these patients is useful. AIM: To analyse the efficiency of technical means to protect the digestive sutures in patients operated in various stages of development of gastric cancer...
2016: Chirurgia
https://www.readbyqxmd.com/read/27813022/a-case-of-retrograde-intussusception-at-roux-en-y-anastomosis-10%C3%A2-years-after-total-gastrectomy-review-of-the-literature
#15
Yuhei Kitasato, Ryuta Midorikawa, Yoshihiro Uchino, Shuko Saku, Taizan Minami, Takahisa Shirahama, Kazumitsu Kiyomatsu, Koji Okuda, Yoshito Akagi, Hiroyuki Tanaka
A 63-year-old man, who had undergone total gastrectomy and Roux-en-Y reconstruction for gastric cancer 10 years previously, was admitted to our hospital with complaints of abdominal pain, palpable abdominal tumor, and hematemesis. On admission, the abdominal tenderness was improving and no abdominal tumor was palpable. Mild inflammatory changes and anemia were noted on blood examination. Abdominal computed tomography revealed a tumor with a layered structure in the left abdomen. The patient was diagnosed with intestinal obstruction secondary to intussusception, and surgery was performed...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27807726/the-preoperative-frailty-versus-inflammation-based-prognostic-score-which-is-better-as-an-objective-predictor-for-gastric-cancer-patients-80%C3%A2-years-and-older
#16
Jun Lu, Long-Long Cao, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Mi Lin, Ru-Hong Tu, Chang-Ming Huang
BACKGROUND: Due to increased life expectancy, the number of elderly patients with gastric cancer is increasing. This study was designed to determine the role of preoperative frailty (PF) as a risk factor for postoperative complications and prognosis in the oldest elderly gastric cancer patients undergoing curative resection. METHODS: A total of 165 patients older than 80 years who underwent radical gastrectomy for primary gastric cancer between 2000 and 2012 were analyzed...
November 2, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27807617/randomized-controlled-clinical-trial-assessing-the-effects-of-oral-nutritional-supplements-in-postoperative-gastric-cancer-patients
#17
Fumihiko Hatao, Kuen-Yuan Chen, Jin-Ming Wu, Ming-Yang Wang, Susumu Aikou, Haruna Onoyama, Nobuyuki Shimizu, Kazuhiko Fukatsu, Yasuyuki Seto, Ming-Tsan Lin
BACKGROUND: Postoperative weight loss and malnutrition are major issues in gastric cancer patients. The concept of oral nutritional supplements (ONS) is gaining widespread acceptance. We investigated the effects of ONS administration on postoperative body weight loss in patients with gastric cancer who had undergone total gastrectomy or distal gastrectomy. METHODS: Patients were randomized to either the treatment or the control group. In both groups, standard surgery for gastric cancer was performed...
November 2, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/27789777/does-a-higher-cutoff-value-of-lymph-node-retrieval-substantially-improve-survival-in-patients-with-advanced-gastric-cancer-time-to-embrace-a-new-digit
#18
Yu-Yin Liu, Wen-Liang Fang, Frank Wang, Jun-Te Hsu, Chun-Yi Tsai, Keng-Hao Liu, Chun-Nan Yeh, Tse-Ching Chen, Ren-Chin Wu, Cheng-Tang Chiu, Ta-Sen Yeh
BACKGROUND: The present study assessed the impact of the retrieval of >25 lymph nodes (LNs) on the survival outcome of patients with advanced gastric cancer after curative-intent gastrectomy. PATIENTS AND METHODS: A total of 5,386 patients who had undergone curative gastrectomy for gastric cancer from 1994 to 2011 were enrolled. The clinicopathological parameters and overall survival (OS) were analyzed according to the number of LNs examined (≤15, n = 916; 16-25, n = 1,458; and >25, n = 3,012)...
October 27, 2016: Oncologist
https://www.readbyqxmd.com/read/27783692/does-total-gastrectomy-provide-better-outcomes-than-distal-subtotal-gastrectomy-for-distal-gastric-cancer-a-systematic-review-and-meta-analysis
#19
Jin Qi, Peng Zhang, Yanan Wang, Hao Chen, Yumin Li
BACKGROUND/AIMS: Total gastrectomy (TG) has shown to be superior regarding low risk of recurrence and readmission to distal subtotal gastrectomy (DG) for treatment of distal stomach cancer, but the incidence of postoperative morbidity and mortality in TG cannot be ignored. Therefore, we performed a meta-analysis to compare the effectiveness between TG and DG for distal stomach cancer. METHODOLOGY: A search in PubMed, EMBASE, the Cochrane Library, Web of Science, Chinese Biomedical Database through January 2016 was performed...
2016: PloS One
https://www.readbyqxmd.com/read/27781243/-application-of-en-bloc-mesogastric-excision-in-the-treatment-of-advanced-gastric-cancer
#20
Fujian Ji, Xuedong Fang, Junnan Jiang, Yuanyu Wu, Ye Feng, Huiling Guo
OBJECTIVE: To evaluate the value of en-bloc mesogastric excision (EME) in the treatment of advanced gastric cancer. METHODS: A retrospective analysis on clinical data of 98 gastric cancer patients who underwent total gastrectomy in China-Japan Union Hospital of Jilin University from January 2013 to December 2015 was carried out, including EME group of 48 cases (according to the mesangial space) and D2 radical group of 50 cases(D2 lymphadenectomy according to the vascular markers)...
October 25, 2016: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
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