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total gastrectomy gastric cancer

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https://www.readbyqxmd.com/read/28090503/intracorporeal-esophagojejunostomy-using-hemi-double-stapling-technique-after-laparoscopic-total-gastrectomy-in-gastric-cancer-patients
#1
Bandar Ali, Cho Hyun Park, Kyo Young Song
PURPOSE: To present the feasibility and safety of Roux-en-Y esophagojejunostomy using hemi-double-stapling technique after laparoscopic total gastrectomy. METHODS: We reviewed the outcomes from 58 consecutive patients with gastric cancer who underwent laparoscopic total gastrectomy. The clinicopathological characteristics including postoperative complications were examined. RESULTS: The mean age and body mass index were 57.3 ± 9.7 years and 23...
January 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28090502/is-noncurative-gastrectomy-always-a-beneficial-strategy-for-stage-iv-gastric-cancer
#2
Chang Min Lee, In Keun Choi, Jong-Han Kim, Da Won Park, Jun Suk Kim, Seong-Heum Park
PURPOSE: The purpose of this study is to suggest a treatment strategy for stage IV gastric cancer by investigating the behavioral difference between initially and recurrent metastatic disease. METHODS: We reviewed the medical records of the patients who underwent chemotherapy alone for metastatic gastric cancer between January 2006 and September 2013. Patients were divided into those who underwent chemotherapy for metastatic disease since initial diagnosis (IM group) and for metastatic recurrence after curative surgery (RM group)...
January 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28078458/superiority-of-laparoscopic-proximal-gastrectomy-with-hand-sewn-esophagogastrostomy-over-total-gastrectomy-in-improving-postoperative-body-weight-loss-and-quality-of-life
#3
Tatsuto Nishigori, Hiroshi Okabe, Shigeru Tsunoda, Hisashi Shinohara, Kazutaka Obama, Hisahiro Hosogi, Shigeo Hisamori, Kikuko Miyazaki, Takeo Nakayama, Yoshiharu Sakai
BACKGROUND: Proximal gastrectomy is not widely performed because the procedure is complicated, particularly under laparoscopy. We developed a simple laparoscopic technique of hand-sewn esophagogastrostomy with an anti-reflux mechanism. This study aimed to evaluate and compare the postoperative body weight loss (BWL) and quality of life (QOL) following laparoscopic proximal gastrectomy (LPG) and laparoscopic total gastrectomy (LTG) in patients with upper gastric cancer. METHODS: We retrospectively analyzed patients with stage I upper gastric cancer undergoing LPG or LTG at Kyoto University Hospital between March 2006 and June 2014...
January 11, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28072447/randomized-clinical-trial-comparing-standard-diet-with-perioperative-oral-immunonutrition-in-total-gastrectomy-for-gastric-cancer
#4
S Ida, N Hiki, H Cho, K Sakamaki, S Ito, K Fujitani, N Takiguchi, Y Kawashima, K Nishikawa, M Sasako, T Aoyama, M Honda, T Sato, S Nunobe, T Yoshikawa
BACKGROUND: Total gastrectomy for gastric cancer is associated with excessive weight loss and decreased calorie intake. Nutritional support using eicosapentaenoic acid modulates immune function and limits catabolism in patients with advanced cancer, but its impact in the perioperative period is unclear. METHODS: This was a randomized phase III clinical trial of addition of eicosapentaenoic acid-rich nutrition to a standard diet in patients having total gastrectomy for gastric cancer...
January 10, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28055030/prognostic-significance-of-preoperative-and-postoperative-plasma-levels-of-ghrelin-in-gastric-cancer-3-year-survival-study
#5
Saeed Soleyman-Jahi, Afshin Abdirad, Amir Afraz Fallah, Sevil Ghasemi, Fatemeh Sadeghi, Reza Heidari, Habibollah Mahmoodzadeh, Kazem Zendehdel
OBJECTIVES: We aimed to investigate prognostic effects of plasma levels of ghrelin before and after gastrectomy in gastric cancer (GC). METHODS: We followed 81 GC patients up to 3 years in this study. They were candidates for curative gastrectomy with or without neoadjuvant chemotherapy. Plasma levels of total and active ghrelins before and after the operation were assessed. Association of plasma levels of ghrelin with survival were assessed and adjusted for other potential prognostic factors using Cox regression analyses...
January 5, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28053815/the-rare-and-challenging-presentation-of-gastric-cancer-during-pregnancy-a-report-of-three-cases
#6
Sergio Pacheco, Enrique Norero, Claudio Canales, José Miguel Martínez, María Elisa Herrera, Carolina Muñoz, Nicolás Jarufe
Pregnancy-associated gastric cancer is extremely rare. In many cases, it is diagnosed at an advanced stage because the symptoms during pregnancy are generally overlooked. We report three cases of gastric cancer during pregnancy with various outcomes. The first case included a patient with stage IV gastric cancer who received palliative chemotherapy. This patient had a preterm birth and died 7 months after diagnosis. The second case received neoadjuvant chemotherapy during pregnancy and a total gastrectomy was performed after delivery...
December 2016: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/28053811/anthropometric-study-of-the-stomach
#7
Eun-Gyeong Lee, Tae-Han Kim, Yeon-Ju Huh, Yun-Suhk Suh, Hye-Sung Ahn, Seong-Ho Kong, Hyuk-Joon Lee, Woo Ho Kim, Han-Kwang Yang
PURPOSE: The aim of this study was to establish an anthropometric reference of the stomach for gastric cancer surgery and a modeling formula to predict stomach length. MATERIALS AND METHODS: Data were retrieved for 851 patients who underwent total gastrectomy at the Seoul National University Hospital between 2008 and 2013. Clinicopathological data and measurements from a formalin-fixed specimen were reviewed. The lengths (cm) of the greater curvature (GC) and lesser curvature (LC) were measured...
December 2016: Journal of Gastric Cancer
https://www.readbyqxmd.com/read/28041649/development-of-a-nomogram-for-predicting-the-risk-of-anastomotic-leakage-after-a-gastrectomy-for-gastric-cancer
#8
R-H Tu, J-X Lin, C-H Zheng, P Li, J-W Xie, J-B Wang, J Lu, Q-Y Chen, L-L Cao, M Lin, C-M Huang
AIMS: To investigate the incidence of and factors associated with anastomotic leakage (AL) following gastrectomy for gastric cancer. METHODS: We retrospectively analyzed 3632 patients who underwent a laparoscopic gastrectomy or open gastrectomy for gastric cancer. A logistic regression model was used to identify the determinant variables, and a nomogram for AL was developed. RESULTS: A total of 3632 patients were included in the study, 50 of whom (1...
December 20, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28024264/fracture-after-gastrectomy-for-gastric-cancer-a%C3%A2-long-term-follow-up-observational-study
#9
Hyun Jin Oh, Chul-Hyun Lim, Byung-Ho Yoon, Seung Bae Yoon, Myong Ki Baeg, Won Chul Kim, Yu Kyung Cho, Jae Myung Park, Myung-Gyu Choi, Han Mo Yoo, Kyo Young Song, Hae Myung Jeon, Cho Hyun Park
AIM: Gastrectomy is a known risk factor for decreased bone mass. We aimed to evaluate the cumulative incidence and predictive factors of fracture in gastric cancer patients who underwent gastrectomy. METHOD: We retrospectively reviewed the records of 1687 patients who underwent gastrectomy for gastric cancer at our hospital between September 1991 and December 2008. The exclusion criteria were stage IV gastric cancer, history of cancer recurrence, medical conditions that cause osteoporosis and high-energy injury...
December 23, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/28009738/lymph-node-metastasis-in-mucosal-gastric-cancer-reappraisal-of-expanded-indication-of-endoscopic-submucosal-dissection
#10
Seung-Young Oh, Kyung-Goo Lee, Yun-Suhk Suh, Min A Kim, Seong-Ho Kong, Hyuk-Joon Lee, Woo Ho Kim, Han-Kwang Yang
OBJECTIVE: To evaluate risk factors for lymph node (LN) metastasis in mucosal gastric cancer, particularly the effect of cellular differentiation, and implications for the indication of endoscopic submucosal dissection (ESD). SUMMARY BACKGROUND DATA: The indication of ESD has been expanded to undifferentiated-type (UD-type) gastric cancer despite risk of LN metastasis. METHODS: Patients who underwent radical gastrectomy for pT1a stage primary gastric adenocarcinoma between 2008 and 2012 were retrospectively analyzed...
January 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28008412/prophylactic-total-gastrectomy-for-hereditary-diffuse-gastric-cancer
#11
Benjamin Shepard, Leon Yoder, Cynthia Holmes
Germline mutations in the CDH1 gene that produces E-cadherin have been implicated in the development of early-onset diffuse gastric cancer, termed hereditary diffuse gastric cancer. The mean age of gastric cancer diagnosis in affected individuals is 37 years. By age 80, CDH1 mutation carriers who fulfill the clinical criteria for hereditary diffuse gastric cancer have an estimated lifetime risk of gastric cancer development of 67% for men and 83% for women. Data suggest that endoscopic surveillance for mutation carriers is largely ineffective...
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27995193/chromoendoscopy-in-combination-with-random-biopsies-does-not-improve-detection-of-gastric-cancer-foci-in-cdh1-mutation-positive-patients
#12
Robert Hüneburg, Tim Marwitz, Peer van Heteren, Tobias J Weismüller, Jonel Trebicka, Ronja Adam, Stefan Aretz, Alberto Perez Bouza, Dimitrios Pantelis, Jörg C Kalff, Jacob Nattermann, Cristian P Strassburg
Background and study aims: Hereditary diffuse gastric cancer (HGGC), an autosomal dominant tumor-syndrome, accounts for 1 % to 3 % of gastric cancers worldwide. Presumably 30 % to 40 % of all patients fulfilling the clinical guidelines for HDGC are carriers of a pathogenic mutation in the CDH1 gene. Patients often show multiple foci of signet ring cell carcinoma at early age and are advised to undergo prophylactic total gastrectomy (PTG). Our aim was to improve the endoscopic detection of HDGC by using an enhanced endoscopic protocol...
December 2016: Endoscopy International Open
https://www.readbyqxmd.com/read/27995033/extremely-high-expression-of-serum-alpha-fetoprotein-level-of-gastric-adenocarcinoma-a-rare-case-with-an-unexpected-well-prognosis
#13
Weihua Gong, Dawei Shou, Ping Gong
INTRODUCTION: Alpha-fetoprotein (AFP)-producing gastric cancer is a relatively rare form of stomach malignancy. Patients with higher serum AFP level (>300 ng/mL) will have a poorer prognosis. CASE DESCRIPTION: In this study, we present a case of 77-year-old woman with an extremely high expression of serum AFP level (>10,000 ng/mL) of gastric cancer. Histological examination revealed gastric adenocarcinoma (Bormann III gastric tumor) invading into the serosal layer and vessel...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27990112/synchronous-and-metachronous-colon-cancers-in-patients-with-gastric-cancer-report-of-2-cases
#14
Byoung Jo Suh
Colorectal cancer is the most common synchronous or metachronous cancer in patients with gastric cancer. I report two cases of synchronous and metachronous colon cancer with gastric cancer. Case 1: A 70-year-old man was admitted to our hospital for the treatment of gastric cancer, which had been diagnosed during esophagogastroduodenoscopy (EGD) screening. The recommended preoperative testing was colonofiberscopy (CFS). The CFS revealed a 3-cm ulcerofungating mass, located 20 cm from the anal verge. The pathological report showed a well-differentiated adenocarcinoma...
September 2016: Case Reports in Oncology
https://www.readbyqxmd.com/read/27988455/delayed-diagnosis-of-wernicke-encephalopathy-with-irreversible-neural-damage-after-subtotal-gastrectomy-for-gastric-cancer-a-case-of-medical-liability
#15
Pamela Tozzo, Luciana Caenazzo, Daniele Rodriguez, Matteo Bolcato
INTRODUCTION: Wernicke's encephalopathy (WE) is a neurological syndrome caused by thiamine deficiency, and clinically characterized by ophthalmoplegia, ataxia and acute confusion. In developed countries, most cases of WE have been seen in alcohol misusers. Other reported causes are gastrointestinal tract surgery, hyperemesis gravidarum, chronic malnutrition, prolonged total parenteral nutrition without thiamine supplementation, and increased nutrient requirements as in trauma or septic shock...
December 1, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27979463/outcomes-of-octogenarians-undergoing-gastrectomy-performed-for-malignancy
#16
Annabelle Teng, Geoffrey Bellini, Erica Pettke, Michael Passeri, David Y Lee, Keith Rose, Anton J Bilchik, Fadi Attiyeh
BACKGROUND: Studies on perioperative outcomes of octogenarians with gastric cancer are limited by small sample size. Our aim was to determine the outcomes of gastrectomy and the variation of treatments associated with advanced age (≥80 y). METHODS: The National Surgical Quality Improvement Program database was queried from 2005 to 2011. Patients who underwent gastrectomy for malignancy were identified using International Classification of Diseases, Ninth Revision and Current Procedural Terminology codes...
January 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27977508/open-versus-hand-assisted-laparoscopic-total-gastric-resection-with-d2-lymph-node-dissection-for-adenocarcinoma-a-case-control-study
#17
Guang-Tan Zhang, Xue-Dong Zhang, Huan-Zhou Xue
OBJECTIVE: A case-control study was conducted to investigate the feasibility and safety of hand-assisted laparoscopic total gastrectomy (HALTG) with D2 lymphadenectomy for gastric cancer as opposed to traditional open total gastrectomy (OTG). METHODS: One hundred fifty-four patients suffering cardia, upper, middle, or whole gastric cancer operated in our department from February 2009 to February 2012 were divided into 2 groups: the open total gastrectomy group (the OTG group) and the hand-assisted laparoscopic total gastrectomy group (the HALTG group)...
December 13, 2016: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/27966431/adjuvant-s-1-chemotherapy-after-curative-resection-of-gastric-cancer-in-chinese-patients-assessment-of-treatment-tolerability-and-associated-risk-factors
#18
W Yeo, K O Lam, A Ly Law, C Cy Lee, C L Chiang, K H Au, F Kf Mo, T H So, K C Lam, W T Ng, L Li
INTRODUCTION: The use of adjuvant chemotherapy with S-1 (tegafur, gimeracil, and oteracil potassium) has been shown to improve the outcome of patients with gastric cancer. There are limited data on the tolerability of S-1 in Chinese patients. In this multicentre retrospective study, we aimed to assess the toxicity profile in local patients. METHODS: Patients with stage II-IIIC gastric adenocarcinoma who had undergone curative resection and who had received S-1 adjuvant chemotherapy were included in the study...
December 14, 2016: Hong Kong Medical Journal, Xianggang Yi Xue za Zhi
https://www.readbyqxmd.com/read/27942875/comparison-of-long-term-survival-and-immediate-postoperative-liver-function-after-laparoscopic-and-open-distal-gastrectomy-for-early-gastric-cancer-patients-with-liver-cirrhosis
#19
Amer Saeed Alshahrani, Ghung-Sik Gong, Moon-Won Yoo
BACKGROUND: Several studies have suggested no difference in the liver function of early gastric cancer (EGC) patients with liver cirrhosis (LC) between laparoscopic and open distal gastrectomy. However, the number of patients and comparison of long-term survival rates between the two groups are limited. The purpose of this study was to compare the long-term survival and immediate postoperative liver function of EGC patients with LC after laparoscopic and open distal gastrectomy. MATERIALS AND METHODS: The clinical data of EGC patients with LC who had no other malignancy and underwent distal gastrectomy at Asan Medical Center between January 2005 and April 2013 were investigated retrospectively...
December 10, 2016: Gastric Cancer
https://www.readbyqxmd.com/read/27936153/impact-of-transient-and-persistent-acute-kidney-injury-on-chronic-kidney-disease-progression-and-mortality-after-gastric-surgery-for-gastric-cancer
#20
Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Sun-Seog Kweon, Soo Wan Kim
Acute kidney injury (AKI) is common after gastric surgery for gastric cancer and associated with adverse outcomes. However, the impact of transient or persistent AKI on clinical outcomes after gastric surgery for gastric cancer has not been described. We performed a retrospective study of 4,886 patients with normal renal function who underwent partial or total gastrectomy for gastric cancer between June 2002 and December 2012. AKI patients were classified as transient and persistent AKI based on the return of serum creatinine to the level indicating no AKI within 7 days...
2016: PloS One
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