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https://www.readbyqxmd.com/read/28545075/an-improved-ant-colony-optimization-algorithm-with-fault-tolerance-for-job-scheduling-in-grid-computing-systems
#1
Hajara Idris, Absalom E Ezugwu, Sahalu B Junaidu, Aderemi O Adewumi
The Grid scheduler, schedules user jobs on the best available resource in terms of resource characteristics by optimizing job execution time. Resource failure in Grid is no longer an exception but a regular occurring event as resources are increasingly being used by the scientific community to solve computationally intensive problems which typically run for days or even months. It is therefore absolutely essential that these long-running applications are able to tolerate failures and avoid re-computations from scratch after resource failure has occurred, to satisfy the user's Quality of Service (QoS) requirement...
2017: PloS One
https://www.readbyqxmd.com/read/28543083/afferent-and-efferent-projections-of-the-anterior-cortical-amygdaloid-nucleus-in-the-mouse
#2
Bernardita Cádiz-Moretti, María Abellán-Álvaro, Cecília Pardo-Bellver, Fernando Martínez-García, Enrique Lanuza
The anterior cortical amygdaloid nucleus (ACo) is a chemosensory area of the cortical amygdala that receives afferent projections from both the main and accessory olfactory bulbs. The role of this structure is unknown, partially due to a lack of knowledge of its connectivity. In this work, we describe the pattern of afferent and efferent projections of the ACo by using fluorogold and biotinylated dextranamines as retrograde and anterograde tracers, respectively. The results show that the ACo is reciprocally connected with the olfactory system and basal forebrain, as well as with the chemosensory and basomedial amygdala...
May 23, 2017: Journal of Comparative Neurology
https://www.readbyqxmd.com/read/28531159/a-family-of-aco-routing-protocols-for-mobile-ad-hoc-networks
#3
Delfín Rupérez Cañas, Ana Lucila Sandoval Orozco, Luis Javier García Villalba, Tai-Hoon Kim
In this work, an ACO routing protocol for mobile ad hoc networks based on AntHocNet is specified. As its predecessor, this new protocol, called AntOR, is hybrid in the sense that it contains elements from both reactive and proactive routing. Specifically, it combines a reactive route setup process with a proactive route maintenance and improvement process. Key aspects of the AntOR protocol are the disjoint-link and disjoint-node routes, separation between the regular pheromone and the virtual pheromone in the diffusion process and the exploration of routes, taking into consideration the number of hops in the best routes...
May 22, 2017: Sensors
https://www.readbyqxmd.com/read/28530657/normal-and-cancerous-mammary-stem-cells-evade-interferon-induced-constraint-through-the-mir-199a-lcor-axis
#4
Toni Celià-Terrassa, Daniel D Liu, Abrar Choudhury, Xiang Hang, Yong Wei, Jose Zamalloa, Raymundo Alfaro-Aco, Rumela Chakrabarti, Yi-Zhou Jiang, Bong Ihn Koh, Heath A Smith, Christina DeCoste, Jun-Jing Li, Zhi-Ming Shao, Yibin Kang
Tumour-initiating cells, or cancer stem cells (CSCs), possess stem-cell-like properties observed in normal adult tissue stem cells. Normal and cancerous stem cells may therefore share regulatory mechanisms for maintaining self-renewing capacity and resisting differentiation elicited by cell-intrinsic or microenvironmental cues. Here, we show that miR-199a promotes stem cell properties in mammary stem cells and breast CSCs by directly repressing nuclear receptor corepressor LCOR, which primes interferon (IFN) responses...
May 22, 2017: Nature Cell Biology
https://www.readbyqxmd.com/read/28528171/accountable-care-organizations-and-the-use-of-cancer-screening
#5
Christian P Meyer, Anna Krasnova, Jesse D Sammon, Stuart R Lipsitz, Joel S Weissman, Maxine Sun, Quoc-Dien Trinh
Cancer preventive services, when used appropriately, result in improved health, better quality of life and decreased costs. For these reasons, cancer preventive services represent important priorities within the Affordable Care Act (ACA). Among the many provisions to improve access to preventive services the ACA introduced Accountable Care Organizations (ACOs) as trajectory to deliver coordinated, high-quality care. In order to evaluate this benchmark, we analyzed (in 2016/Boston) screening prevalence of breast cancer, a recommended screening test according to the United States Preventive Services Task Force (USPSTF), and prostate cancer, for which screening is no longer recommended by the USPSTF, among traditional Medicare beneficiaries and those enrolled in ACOs...
May 17, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28523172/roles-of-roflumilast-a-selective-phosphodiesterase-4-inhibitor-in-airway-diseases
#6
REVIEW
Theerasuk Kawamatawong
Asthma and chronic obstructive pulmonary disease (COPD) are common chronic respiratory diseases. Both diseases have incompletely distinct pathophysiology, clinical manifestation, and treatment responsiveness. Pulmonary and systemic inflammations are the hallmarks of COPD. Most asthma responds to inhaled corticosteroid (ICS) treatment. In contrast, COPD is a corticosteroid-resistant disease. Bronchodilators are a preferred treatment method of COPD, with the aim of improving symptoms and preventing exacerbation...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28514835/genistein-has-beneficial-effects-on-hepatic-steatosis-in-high-fat-high-sucrose-diet-treated-rats
#7
Huanhuan Liu, Huijia Zhong, Yimin Yin, Zhuoqin Jiang
Genistein, a kind of phytoestrogen abundant in soybeans, is beneficial for alleviating non-alcoholic fatty liver disease (NAFLD), but the specific mechanism was not clearly understood. This study was designed to determine the effect of genistein on NAFLD and explore the possible mechanism. 36 male Sprague-Dawley rats were divided into 4 groups: the control group, high fat-high sucrose diet (HFS) group, HFS with 4mg/kg body weight genistein, and HFS with 8mg/kg body weight genistein. 12 weeks later, serum and hepatic lipid profiles, liver histopathological examination were characterized...
May 13, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28513765/factors-associated-with-suicidal-ideation-among-university-students
#8
Hugo Gedeon Barros Dos Santos, Samira Reschetti Marcon, Mariano Martínez Espinosa, Makilin Nunes Baptista, Paula Mirianh Cabral de Paulo
Objective: to analyze the factors associated with suicidal ideation in a representative sample of university students. Methods: cross-sectional study, carried out with 637 students of the Federal University of Mato Grosso. The presence of suicidal ideation, demographic and socioeconomic variables, use of alcohol through the Alcohol, Smoking and Substance Involvement Screening Test, and depressive symptoms (Major Depression Inventory) were investigated. Bivariate analysis was performed with the Chi-square test and multivariate analysis using the Poisson regression model...
May 15, 2017: Revista Latino-americana de Enfermagem
https://www.readbyqxmd.com/read/28510199/taxonomic-placement-of-paphiopedilum-rungsuriyanum-cypripedioideae-orchidaceae-based-on-morphological-cytological-and-molecular-analyses
#9
Yung-I Lee, Mei-Chu Chung, Kongmany Sydara, Onevilay Souliya, Sulivong Luang Aphay
BACKGROUND: Paphiopedilum rungsuriyanum from Northern Laos was discovered and described in 2014. It is characterized by having miniature tessellated leaves, a flower having a helmet shaped lip with a V-shaped neckline, and a semi-lunate, 3-dentate staminode with an umbo. These morphological features distinguish P. rungsuriyanum from the other known sections/subgenera of Paphiopedilum, making it difficult to group with existing infrageneric units. RESULTS: Paphiopedilum rungsuriyanum has chromosome number of 2n = 26...
December 2017: Botanical Studies (Taipei, Taiwan)
https://www.readbyqxmd.com/read/28495077/consensus-on-the-asthma-copd-overlap-syndrome-acos-between-the-spanish-copd-guidelines-gesepoc-and-the-spanish-guidelines-on-the-management-of-asthma-gema
#10
Vicente Plaza, Francisco Álvarez, Myriam Calle, Ciro Casanova, Borja G Cosío, Antolín López-Viña, Luís Pérez de Llano, Santiago Quirce, Miguel Román-Rodríguez, Juan José Soler-Cataluña, Marc Miravitlles
Following a proposal by the Spanish Society of Pulmonology and Thoracic Surgery (SEPAR), sponsor of the Spanish COPD Guidelines (GesEPOC) and the Spanish Guidelines on the Management of Asthma (GEMA), authors of both papers have unified the criteria for the diagnosis of asthma-COPD overlap syndrome (ACOS). This consensus defines ACOS as the presence in a given patient of three elements: significant smoking exposure, chronic airflow limitation and asthma. Diagnosis is confirmed when a patient (35years of age or older), smoker or ex-smoker of more than 10 pack-years, presents airflow limitation (post-bronchodilator FEV1/FVC<0...
May 8, 2017: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/28494181/characterization-of-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-a-qualitative-analysis
#11
Claudie Rodrigue, Marie-France Beauchesne, Valérie Mallette, Catherine Lemière, Pierre Larivée, Lucie Blais
Approximately 15-20% of patients with chronic obstructive pulmonary disease (COPD) also display characteristics of asthma. In May 2014, the asthma-COPD overlap syndrome (ACOS) was briefly addressed in the Global Initiative for Asthma (GINA) and Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy documents. We evaluated how pulmonologists diagnose and treat ACOS and how they assess its control. Pulmonologists from two university healthcare centers, having ≥ 1 year experience, treating patients with asthma, COPD, or ACOS, were invited to participate in focus groups...
May 11, 2017: COPD
https://www.readbyqxmd.com/read/28491940/data-on-eleven-sesquiterpenoids-from-the-cultured-mycelia-of-ganoderma-capense
#12
Zhen Tan, Jinlian Zhao, Jimei Liu, Min Zhang, Ridao Chen, Kebo Xie, Jungui Dai
The data included in this paper are associated with the research article entitled "Sesquiterpenoids from the cultured mycelia of Ganoderma capense" [1]. (1)H NMR, (13)C NMR, DEPT, HSQC, (1)H-(1)H COSY, HMBC, NOESY, HRESIMS, and IR spectra of Ganodermanol A-H (1-11), together with Mo2(AcO)4-induced CD spectrum of Ganodermanol A, CD spectra of Ganodermanol D-E were included in the Data in Brief article. In addition, the cytotoxicities and anti-HIV-1 activity of isolated compounds were also included in the Data in Brief article...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28487710/transcriptome-analysis-of-cell-wall-and-nac-domain-transcription-factor-genes-during-elaeis-guineensis-fruit-ripening-evidence-for-widespread-conservation-within-monocot-and-eudicot-lineages
#13
Timothy J Tranbarger, Kim Fooyontphanich, Peerapat Roongsattham, Maxime Pizot, Myriam Collin, Chatchawan Jantasuriyarat, Potjamarn Suraninpong, Somvong Tragoonrung, Stéphane Dussert, Jean-Luc Verdeil, Fabienne Morcillo
The oil palm (Elaeis guineensis), a monocotyledonous species in the family Arecaceae, has an extraordinarily oil rich fleshy mesocarp, and presents an original model to examine the ripening processes and regulation in this particular monocot fruit. Histochemical analysis and cell parameter measurements revealed cell wall and middle lamella expansion and degradation during ripening and in response to ethylene. Cell wall related transcript profiles suggest a transition from synthesis to degradation is under transcriptional control during ripening, in particular a switch from cellulose, hemicellulose, and pectin synthesis to hydrolysis and degradation...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28461355/bending-the-spending-curve-by-altering-care-delivery-patterns-the-role-of-care-management-within-a-pioneer-aco
#14
John Hsu, Mary Price, Christine Vogeli, Richard Brand, Michael E Chernew, Sreekanth K Chaguturu, Eric Weil, Timothy G Ferris
Accountable care organizations (ACOs) appear to lower medical spending, but there is little information on how they do so. We examined the impact of patient participation in a Pioneer ACO and its care management program on rates of emergency department (ED) visits and hospitalizations and on Medicare spending. We used data for the period 2009-14, exploiting naturally staggered program entry to create concurrent controls to help isolate the program effects. The care management program (the ACO's primary intervention) targeted beneficiaries with elevated but modifiable risks for future spending...
May 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/28461299/th-2-signature-in-chronic-airway-diseases-towards-the-extinction-of-asthma-copd-overlap-syndrome
#15
Borja G Cosío, Luis Pérez de Llano, Antolin Lopez Viña, Alfons Torrego, Jose Luis Lopez-Campos, Joan B Soriano, Eva Martinez Moragon, Jose Luis Izquierdo, Irina Bobolea, Javier Callejas, Vicente Plaza, Marc Miravitlles, Juan Jose Soler-Catalunya
We aimed to describe the differences and similarities between patients with chronic obstructive airway disease classified on the basis of classical diagnostic labels (asthma, chronic obstructive pulmonary disease (COPD), or asthma-COPD overlap (ACOS)) or according to the underlying inflammatory pattern (Th-2 signature, either Th-2-high or Th-2-low).We performed a cross-sectional study of patients aged ≥40 years and with a post-bronchodilator forced expiratory volume in 1 s to forced vital capacity ratio ≤0...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28461298/differences-between-asthma-copd-overlap-syndrome-and-adult-onset-asthma
#16
Minna Tommola, Pinja Ilmarinen, Leena E Tuomisto, Lauri Lehtimäki, Jussi Haanpää, Onni Niemelä, Hannu Kankaanranta
Differences between asthma-COPD overlap syndrome (ACOS) and adult-onset asthma are poorly understood. This study aimed to evaluate these differences in a clinical cohort of patients with adult-onset asthma, as a part of the Seinäjoki Adult Asthma Study (SAAS).188 patients were diagnosed with adult-onset asthma and re-evaluated 12 years after diagnosis. They were divided into three groups based on smoking history and post bronchodilator spirometry values: 1) never- and ex-smokers with <10 smoked pack-years; 2) non-obstructive (forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ≥0...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28461292/defining-asthma-copd-overlap-syndrome-a-population-based-study
#17
Tobias N Bonten, Marise J Kasteleyn, Renee de Mutsert, Pieter S Hiemstra, Frits R Rosendaal, Niels H Chavannes, Annelies M Slats, Christian Taube
Asthma-chronic obstructive pulmonary disease (COPD) overlap syndrome (ACOS) seems an important clinical phenotype, but multiple definitions have been proposed. This study's objectives were to assess the effect of different ACOS definitions on prevalence, patient characteristics and exacerbations.5675 individuals aged 45-65 years, with 846 asthma/COPD patients, were included in the Netherlands Epidemiology of Obesity study between 2008 and 2012, and followed-up for a median of 1.8 years. ACOS was defined by recent consensus criteria and five other definitions, based on registry, questionnaires and lung function...
May 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28460847/radiographic-evidence-of-sinonasal-inflammation-in-asthma-chronic-obstructive-pulmonary-disease-overlap-syndrome-an-underrecognized-association
#18
Satoshi Hamada, Shuji Tatsumi, Yoshiki Kobayashi, Hisako Matsumoto, Hirotaka Yasuba
BACKGROUND: Sinonasal inflammation on both clinical examinations and imaging significantly impacts both asthma and chronic obstructive pulmonary disease (COPD). OBJECTIVE: The objective of this study was to examine the association between sinonasal inflammation and asthma-COPD overlap syndrome (ACOS). METHODS: A total of 112 patients with a ratio of forced expiratory volume in 1 s to forced vital capacity of less than 70% were enrolled. COPD, asthma, and ACOS were clinically diagnosed according to the 2014 Global Initiative for Asthma and Global Initiative for Chronic Obstructive Lung Disease guidelines...
April 28, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28448780/integration-strategies-of-pharmacists-in-primary-care-based-accountable-care-organizations-a-report-from-the-accountable-care-organization-research-network-services-and-education
#19
Tina Joseph, Genevieve M Hale, Sara M Eltaki, Yesenia Prados, Renee Jones, Matthew J Seamon, Cynthia Moreau, Stephanie A Gernant
BACKGROUND: The accountable care organization (ACO) is an innovative health care delivery model centered on value-based care. ACOs consisting of primary care providers are increasingly becoming commonplace in practice; however, medication management remains suboptimal. PROGRAM DESCRIPTION: As experts in medication management, pharmacists perform direct patient care and assist in the transition from one provider to another, which places them in an ideal position to manage multiple aspects of patient care...
May 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28444095/judicial-demand-of-medications-through-the-federal-justice-of-the-state-of-paran%C3%A3
#20
Renato Mitsunori Nisihara, Ana Carolina Possebom, Luiza de Martino Cruvinel Borges, Ana Claudia Athanasio Shwetz, Fernanda Francis Benevides Bettes
Objective: To describe the profile of lawsuits related to drug requests filled at the Federal Justice of the State of Paraná. Methods: A cross-sectional study, and the data were obtained through consulting the lawsuits at the online system of the Federal Justice of Paraná. Results: Out of 347 lawsuits included in the study, 55% of plaintiffs were women, with a median age of 56 years. Oncology was the field with more requests (23.6%), and the highest mean costs...
January 2017: Einstein
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