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https://www.readbyqxmd.com/read/28917081/evaluation-of-the-ecstasy-influence-on-tramadol-and-its-main-metabolite-plasma-concentration-in-rats
#1
Bardia Jamali, Behjat Sheikholeslami, Yalda Hosseinzadeh Ardakani, Hoda Lavasani, Mohammad-Reza Rouini
BACKGROUND: Tramadol is prone to be abused alone, or in combination with 3,4-methylenedioxymethamphetamine (MDMA, Ecstasy). It was reported that 95% of people with a history of substance abuse in the United States used tramadol in 2004. According to the WHO report in 2016, there was a growing number of tramadol abusers alone or in combination with psychoactive substances such as MDMA in particular in some Middle East countries. Higher concentrations of tramadol in plasma may lead to adverse drug reactions or lethal intoxication...
September 16, 2017: Drug Metabolism and Personalized Therapy
https://www.readbyqxmd.com/read/28915840/evolution-and-bad-prognostic-value-of-advanced-glycation-end-products-after-acute-heart-failure-relation-with-body-composition
#2
Beatriz Paradela-Dobarro, Ángel Fernández-Trasancos, Diana Bou-Teen, Sonia Eiras, Rocío González-Ferreiro, Rosa M Agra, Alfonso Varela-Román, Ana I Castro-Pais, Marcos C Carreira, Felipe F Casanueva, Ezequiel Álvarez, José R González-Juanatey
AIM: The role of advanced glycation end products (AGEs) and their soluble receptor (sRAGE) on the progression and prognosis of acute heart failure (HF) was analysed in relation with metabolic parameters as body composition and nutritional status. METHODS: A hundred and fifty consecutive patients were included in a prospective clinical study during hospitalization by acute HF. Detailed medical history, physical examination, electrocardiogram, echocardiogram and vein peripheral blood were taken for all patients...
September 15, 2017: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/28914959/nocturia-is-associated-with-poor-sleep-quality-among-older-women-in-the-study-of-osteoporotic-fractures
#3
Constance H Fung, Camille P Vaughan, Alayne D Markland, Alison J Huang, Michael N Mitchell, Donald L Bliwise, Sonia Ancoli-Israel, Susan Redline, Cathy A Alessi, Katie Stone
OBJECTIVES: (1) To examine relationships between frequency of nocturia and self-reported sleep quality and objective sleep measures in older women, and (2) to estimate the amount of variation in sleep measures that is specifically attributable to frequency of nocturia. DESIGN AND SETTING: Secondary, cross sectional analysis of the multicenter prospective cohort Study of Osteoporotic Fractures (SOF). PARTICIPANTS: Community-dwelling women aged ≥80 years...
September 15, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28914601/left-ventricular-long-axis-function-assessed-with-cardiac-cine-mr-imaging-is-an-independent-predictor-of-all-cause-mortality-in-patients-with-reduced-ejection-fraction-a-multicenter-study
#4
Simone Romano, Robert M Judd, Raymond J Kim, Han W Kim, Igor Klem, John F Heitner, Dipan J Shah, Jennifer Jue, Afshin Farzaneh-Far
Purpose To evaluate the prognostic value of a simple index of left ventricular (LV) long-axis function-lateral mitral annular plane systolic excursion (MAPSE)-in a large multicenter population of patients with reduced ejection fraction (EF) who were undergoing cardiac magnetic resonance (MR) imaging. Materials and Methods This retrospective study included 1040 consecutive patients (mean age, 59.5 years ± 15.8) at four U.S. medical centers who were undergoing cardiac MR imaging for assessment of LV dysfunction with EF less than 50%...
September 14, 2017: Radiology
https://www.readbyqxmd.com/read/28913876/an-assessment-of-participant-described-interprofessional-oral-health-referral-systems-across-rurality
#5
Sean G Boynes, Abigail Lauer, Mark Deutchman, Amy B Martin
PURPOSE: As a means to identify and quantify oral health interprofessional collaborative practice (IPP), we examined participant-described medical-to-dental (M2D) referral networks and how they function across rurality. METHODS: We conducted a cross-sectional survey on the appraisal of IPP referral systems in 2016. Secondarily, we examined if rural health clinics (RHCs) have different experiences with M2D referrals compared to other practice types. Independent variables included geographic and organizational indicators, referral system attributes, and respondent characteristics...
September 15, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28912113/mobile-augmented-reality-as-a-feature-for-self-oriented-blended-learning-in-medicine-randomized-controlled-trial
#6
Christoph Noll, Ute von Jan, Ulrike Raap, Urs-Vito Albrecht
BACKGROUND: Advantages of mobile Augmented Reality (mAR) application-based learning versus textbook-based learning were already shown in a previous study. However, it was unclear whether the augmented reality (AR) component was responsible for the success of the self-developed app or whether this was attributable to the novelty of using mobile technology for learning. OBJECTIVE: The study's aim was to test the hypothesis whether there is no difference in learning success between learners who employed the mobile AR component and those who learned without it to determine possible effects of mAR...
September 14, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28911021/effects-of-lifestyle-modification-on-an-exaggerated-blood-pressure-response-to-exercise-in-normotensive-females
#7
Ryoma Michishita, Masanori Ohta, Masaharu Ikeda, Ying Jiang, Hiroshi Yamato
BACKGROUND: This study was designed to examine the effects of a lifestyle modification on the improvement in an exaggerated systolic blood pressure (SBP) response to exercise in normotensive females. METHODS: The subjects were 78 normotensive females with (n = 25) and without (n = 53) an exaggerated SBP response to exercise who were not taking any medications. An exaggerated SBP response to exercise was defined according to the criteria of the Framingham Study (peak SBP: ≥190 mm Hg)...
October 1, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28910559/the-impact-of-fda-regulatory-activities-on-incident-dispensing-of-laba-containing-medication-2005-2011
#8
Meghan A Baker, Melissa G Butler, Sally Seymour, Fang Zhang, Yute Wu, Ann Chen Wu, Mark S Levenson, Pingsheng Wu, Aarthi Iyer, Sengwee Toh, Solomon Iyasu, Esther H Zhou
BACKGROUND: Evidence of safety issues associated with long-acting beta2-agonist (LABA) treatment has led to multiple regulatory activities by the U.S. Food and Drug Administration (FDA) on this class of medications. OBJECTIVE: This study describes the impact of the regulatory activities on incident LABA-containing medication dispensing. METHODS: A monthly rolling cohort of asthma patients who were eligible to initiate a LABA-containing product was created in the Mini-Sentinel Distributed Database between January 2005 and June 2011...
September 14, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/28910205/gender-differences-in-the-relationship-between-sex-hormone-deficiency-and-soft-drusen
#9
Han Jo Kwon, Seung Min Lee, Kang Yeun Pak, Sung Who Park, Ji Eun Lee, Ik Soo Byon
PURPOSE: To investigate the association between sex hormone deficiency and soft drusen in women and men. MATERIALS AND METHODS: We retrospectively reviewed the medical records and fundus photographs of subjects who underwent a health screening for additional examination of climacterium and age-related changes including sex hormone status. In women, sex hormone deficiency was defined as cessation of menstruation that had lasted for at least 12 months and follicular stimulating hormone (FSH) levels ≥ 25 mIU/mL; in men, it was defined as testosterone levels ≤ 3...
September 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28904248/the-system-and-human-resources-for-occupational-health-in-republic-of-indonesia-for-japanese-enterprises-to-manage-proper-occupational-health-activities-at-overseas-workplaces
#10
Ko Hiraoka, Shigeyuki Kajiki, Yuichi Kobayashi, Nuri Purwito Adi, Dewi Sumaryani Soemarko, Masamichi Uehara, Shigemoto Nakanishi, Koji Mori
OBJECTIVES: To consider the appropriate occupational health system for Japanese enterprises in Indonesia with information on the regulations and development of the specialists. METHODS: In this study, we used the information-gathering checklist developed by Kajiki et al. Along with literature and internet surveys, we surveyed local corporations owned and operated by Indonesians, central government agencies in charge of medical and health issues, a Japanese independent administrative agency supporting subsidiaries of overseas Japanese enterprises, and an educational institution formulating specialized occupational physician training curricula...
September 13, 2017: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/28904076/residual-angina-after-elective-percutaneous-coronary-intervention-in-patients-with-diabetes-mellitus
#11
Anna Grodzinsky, Mikhail Kosiborod, Fengming Tang, Philip G Jones, Darren K McGuire, John A Spertus, John F Beltrame, Jae-Sik Jang, Abhinav Goyal, Neel M Butala, Robert W Yeh, Suzanne V Arnold
BACKGROUND: Previous studies suggest that among patients with stable coronary artery disease, patients with diabetes mellitus (DM) have less angina and more silent ischemia when compared with those without DM. However, the burden of angina in diabetic versus nondiabetic patients after elective percutaneous coronary intervention (PCI) has not been recently examined. METHODS AND RESULTS: In a 10-site US PCI registry, we assessed angina before and at 1, 6, and 12 months after elective PCI with the Seattle Angina Questionnaire angina frequency score (range, 0-100, higher=better)...
September 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28902900/possible-clinical-effects-of-molecular-hydrogen-h2-delivery-during-hemodialysis-in-chronic-dialysis-patients-interim-analysis-in-a-12-month-observation
#12
Masaaki Nakayama, Noritomo Itami, Hodaka Suzuki, Hiromi Hamada, Naoyuki Osaka, Ryo Yamamoto, Kazumasa Tsunoda, Hirofumi Nakano, Kimio Watanabe, Wan-Jun Zhu, Yukio Maruyama, Hiroyuki Terawaki, Shigeru Kabayama, Ryoichi Nakazawa, Mariko Miyazaki, Sadayoshi Ito
BACKGROUND AND AIM: It is supposed that enhanced oxidative stress and inflammation are involved with the poor clinical outcomes in patients on chronic dialysis treatment. Recent studies have shown that molecular hydrogen (H2) is biologically active as an anti-inflammatory agent. Thus, we developed a novel hemodialysis (E-HD) system which delivers H2 (30 to 80 ppb)-enriched dialysis solution, to conduct a prospective observational study (UMIN000004857) in order to compare the long-term outcomes between E-HD and conventional-HD (C-HD) in Japan...
2017: PloS One
https://www.readbyqxmd.com/read/28902857/willingness-to-use-pre-exposure-prophylaxis-for-hiv-prevention-among-men-who-have-sex-with-men-in-malaysia-findings-from-an-online-survey
#13
Sin How Lim, Gitau Mburu, Adam Bourne, Joselyn Pang, Jeffrey A Wickersham, Clayton Koh Thuan Wei, Ilias Adam Yee, Bangyuan Wang, Matteo Cassolato, Iskandar Azwa
OBJECTIVE: We examined willingness to use pre-exposure prophylaxis (PrEP) for HIV prevention among men who have sex with men (MSM) in Malaysia. METHODS: An online survey of 990 MSM was conducted between March and April 2016. Eligibility criteria included being biological male, Malaysian citizen, 18 years of age or above, identifying as MSM, and being HIV negative or unknown status. Participants' demographics, sexual and drug use behaviors, attitudes towards PrEP, and preferences regarding future access to PrEP were collected...
2017: PloS One
https://www.readbyqxmd.com/read/28901872/-speaking-kleinian-susan-isaacs-as-ursula-wise-and-the-inter-war-popularisation-of-psychoanalysis
#14
Michal Shapira
How did the complex concepts of psychoanalysis become popular in early twentieth-century Britain? This article examines the contribution of educator and psychoanalyst Susan Isaacs (1885-1948) to this process, as well as her role as a female expert in the intellectual and medical history of this period. Isaacs was one of the most influential British psychologists of the inter-war era, yet historical research on her work is still limited. The article focuses on her writing as 'Ursula Wise', answering the questions of parents and nursery nurses in the popular journal Nursery World, from 1929 to 1936...
October 2017: Medical History
https://www.readbyqxmd.com/read/28899441/use-of-proton-pump-inhibitors-is-associated-with-depression-a-population-based-study
#15
Alice Laudisio, Raffaele Antonelli Incalzi, Antonella Gemma, Silvia Giovannini, Maria Rita Lo Monaco, Davide L Vetrano, Luca Padua, Roberto Bernabei, Giuseppe Zuccalà
Treatment with proton-pump inhibitors (PPIs) might be associated with neuropsychological side effects. We examined the association between use of PPIs and depressive symptoms in an elderly population. Mood was assessed by the 30-item Geriatric Depression Scale (GDS) in all 344 inhabitants of Tuscania (Italy) aged 75 years and over, without exclusion criteria; depression was defined by a GDS score ≥11. Use of PPIs was associated with a higher GDS score in linear regression analysis (B = 2.43; 95% CI = 0.49-4...
September 13, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28895980/coping-with-the-pain-of-elderly-pain-patients-nursing-approach
#16
Burcu Babadağ, Güler Balcı Alparslan, Sacit Güleç
OBJECTIVES: This study was designed to examine methods used by elderly patients to cope with pain and serve as a guide for nurses. METHODS: This descriptive survey was carried out with geriatric patients (n=100) aged 60 years or more in inpatient Algology Unit of a university hospital between November 28, 2014 and January 28, 2015. Data were collected using descriptive characteristics questionnaire prepared based on review of the literature and via one-on-one interviews using Pain Coping Questionnaire (PCQ)...
April 2017: Aǧrı: Ağrı (Algoloji) Derneği'nin Yayın Organıdır, the Journal of the Turkish Society of Algology
https://www.readbyqxmd.com/read/28894582/prediction-model-and-treatment-of-high-output-ileostomy-in-colorectal-cancer-surgery
#17
Shiki Fujino, Norikatsu Miyoshi, Masayuki Ohue, Yuske Takahashi, Masayoshi Yasui, Keijiro Sugimura, Hirohumi Akita, Hidenori Takahashi, Shogo Kobayashi, Masahiko Yano, Masato Sakon
The aim of the present study was to examine the risk factors of high-output ileostomy (HOI), which is associated with electrolyte abnormalities and/or stoma complications, and to create a prediction model. The medical records of 68 patients who underwent colorectal cancer surgery with ileostomy between 2011 and 2016 were retrospectively investigated. All the patients underwent surgical resection for colorectal cancer at the Osaka Medical Center for Cancer and Cardiovascular Diseases (Osaka, Japan). A total of 7 patients with inadequate data on ileostomy output were excluded...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28893471/illness-perceptions-and-negative-responses-from-medical-professionals-in-patients-with-fibromyalgia-association-with-patient-satisfaction-and-number-of-hospital-visits
#18
Mieko Homma, Hirono Ishikawa, Takahiro Kiuchi
OBJECTIVE: To examine whether illness perceptions among patients with fibromyalgia and negative responses from medical professionals correlate with their satisfaction with their physicians or with their number of hospital visits. METHODS: Questionnaires were sent by post to members of the Japan Fibromyalgia Support Association. Measures collected included, as independent variables, the Brief Illness Perception Questionnaire and the Illness Invalidation Inventory; and as outcomes, the Patient Satisfaction Consultation Questionnaire and the number of hospital visits...
August 30, 2017: Patient Education and Counseling
https://www.readbyqxmd.com/read/28893200/an-after-hours-gp-clinic-in-regional-australia-appropriateness-of-presentations-and-impact-on-local-emergency-department-presentations
#19
Kristy Payne, Tegan Dutton, Kate Weal, Maree Earle, Ross Wilson, Jannine Bailey
BACKGROUND: After hours general practice clinics provide medical attention for clients with non-emergency situations but are seeking immediate treatment and unable to wait for a general practitioner during routine opening hours. Evidence on the impact that after hours clinics have on emergency department presentations is equivocal. This study explored outcomes of the Bathurst After Hours General Practice Clinic (BAHGPC). Specifically it examined: clients' perceived urgency of, and satisfaction with their presentation to the BAHGPC; general practitioners' perception of the appropriateness of presentations to the BAHGPC; and whether the frequency of non-urgent and semi-urgent emergency department presentations at Bathurst Base Hospital has changed since the opening of the BAHGPC...
September 11, 2017: BMC Family Practice
https://www.readbyqxmd.com/read/28892933/evaluation-of-the-relationship-between-serum-25-hydroxy-vitamin-d-and-hypertension-in-hamadan-iran-a-case-control-study
#20
Behshad Naghshtabrizi, Shiva Borzouei, Pedram Bigvand, Mohamad Ali Seifrabiei
INTRODUCTION: Hypertension or high blood pressure is one of the main reasons of fatality in the world. The role of vitamin D in developing hypertension has not been proved yet. Some studies have shown positive correlation between low serum vitamin D level and hypertension. Due to this fact, recognising hypertension risk factors such as potential impact of low serum vitamin D level seems to be required. AIM: This study was conducted to evaluate potential impact of serum vitamin D level on hypertension...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
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