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https://www.readbyqxmd.com/read/29884803/cannabinoids-for-the-treatment-of-rheumatic-diseases-where-do-we-stand
#1
REVIEW
Daphna Katz-Talmor, Itay Katz, Bat-Sheva Porat-Katz, Yehuda Shoenfeld
As medical use of cannabis is increasingly legalized worldwide, a better understanding of the medical and hazardous effects of this drug is imperative. The pain associated with rheumatic diseases is considered a prevalent indication for medicinal cannabis in various countries. Thus far, preliminary clinical trials have explored the effects of cannabis on rheumatoid arthritis, osteoarthritis and fibromyalgia; preliminary evidence has also found an association between the cannabinoid system and other rheumatic conditions, including systemic sclerosis and juvenile idiopathic arthritis...
June 8, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29880577/the-clinician-impact-and-financial-cost-to-the-nhs-of-litigation-over-pregabalin-a-cohort-study-in-english-primary-care
#2
Richard Croker, Darren Smyth, Alex J Walker, Ben Goldacre
OBJECTIVES: Following litigation over pregabalin's second-use medical patent for neuropathic pain, National Health Service (NHS) England was required by the court to instruct general practitioners (GPs) to prescribe the branded form (Lyrica) for pain. Pfizer's patent was found invalid in 2015, a ruling subject to ongoing appeals. If the Supreme Court appeal in February 2018, whose judgement is awaited, is unsuccessful, the NHS can seek to reclaim excess prescribing costs. We set out to describe the variation in prescribing of pregabalin as branded Lyrica, geographically and over time; to determine how clinicians responded to the NHS England instruction to GPs; and to model excess costs to the NHS attributable to the legal judgements...
June 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29879946/-when-helpers-hurt-women-s-and-midwives-stories-of-obstetric-violence-in-state-health-institutions-colombo-district-sri-lanka
#3
Dinusha Perera, Ragnhild Lund, Katarina Swahnberg, Berit Schei, Jennifer J Infanti
BACKGROUND: The paper explores how age, social position or class, and linguistic and cultural background intersect and place women in varying positions of control and vulnerability to obstetric violence in state health institutions in Colombo district, Sri Lanka. Obstetric violence occurs during pregnancy, childbirth and the immediate postpartum period; hence, it is violence that directly affects women. The authors aim to break the traditional culture of silence around obstetric violence and bring attention to the resulting implications for quality of care and patient trust in obstetric care facilities or providers...
June 7, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29865933/complex-regional-pain-syndrome-type-1-in-the-medico-legal-setting-high-rates-of-somatoform-disorders-opiate-use-and-diagnostic-uncertainty
#4
Christopher Bass, Gregory Yates
Objective The aim of this study was to review demographic and clinical characteristics of patients with complex regional pain syndrome type 1 (CRPS) seen in a UK medico-legal setting - particularly the relationship between CRPS and somatoform disorders. Methods Fifty consecutive cases of CRPS (interviewed 2005-2016) undergoing psychiatric assessment were reviewed. A systematic assessment of mental states was conducted via interview and examination of medical/psychiatric records. Thirty patients also completed the Brief Illness Perception Questionnaire (BIPQ)...
January 1, 2018: Medicine, Science, and the Law
https://www.readbyqxmd.com/read/29813166/medical-malpractice-following-carpal-tunnel-surgery
#5
Joseph A Gil, Steven Bokshan, Timothy Genovese, Christopher Got, Alan H Daniels
There is a paucity of literature examining the reasons for litigation following carpal tunnel surgery in the United States. The purpose of this retrospective study was to examine a nationwide legal database to describe the most frequent reasons for malpractice litigation following carpal tunnel surgery. All malpractice claims that occurred following carpal tunnel surgery were included. In total, 46 cases met inclusion criteria, representing 15 male and 31 female patients with an average age of 46.4 years (±14...
May 29, 2018: Orthopedics
https://www.readbyqxmd.com/read/29807184/retention-of-non-absorbable-hemostatic-materials-retained-surgical-sponge-gossypiboma-textiloma-gauzoma-muslinoma-after-spinal-surgery-a-systematic-review-of-cases-reported-during-last-half-century
#6
REVIEW
Mehmet Turgut, Ali Akhaddar, Ahmet T Turgut
OBJECTIVE: Retention of non-absorbable hemostatic materials (RNHMs) called retained surgical sponge, gauzoma, gossypiboma, muslinoma, or textiloma is a rarely seen surgical complication after spinal surgery that may remain asymptomatic for many years and may represent a diagnostic difficulty with associated medico-legal implications. METHODS: We performed a systematic review of the English-language literature published between 1965 and 2017, accessed through four popular databases...
May 25, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29789018/pain-clinic-definitions-in-the-medical-literature-and-u-s-state-laws-an-integrative-systematic-review-and-comparison
#7
REVIEW
Barbara Andraka-Christou, Joshua B Rager, Brittany Brown-Podgorski, Ross D Silverman, Dennis P Watson
BACKGROUND: In response to widespread opioid misuse, ten U.S. states have implemented regulations for facilities that primarily manage and treat chronic pain, called "pain clinics." Whether a clinic falls into a state's pain clinic definition determines the extent to which it is subject to oversight. It is unclear whether state pain clinic definitions model those found in the medical literature, and potential differences lead to discrepancies between scientific and professionally guided advice found in the medical literature and actual pain clinic practice...
May 22, 2018: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/29788102/legalization-of-medicinal-marijuana-has-minimal-impact-on-use-patterns-in-patients-with-inflammatory-bowel-disease
#8
Ami M Merker, Mahrukh Riaz, Sonia Friedman, Jessica R Allegretti, Joshua Korzenik
Background: Patients with inflammatory bowel disease (IBD) have reported use of marijuana to treat symptoms of the disease, yet its classification as a Schedule 1 substance by the federal government has restricted its use. In 2012, Massachusetts legalized medicinal marijuana. We aimed to assess the impact of legalization on use in IBD. Methods: Consecutive patients with IBD, cared for at a tertiary care center in Boston, were surveyed regarding use of marijuana, including its perceived benefits and attitudes...
May 18, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29697632/addressing-the-opioid-epidemic-a-review-of-the-role-of-plastic-surgery
#9
Annie M Q Wang, Helene Retrouvey, Kyle R Wanzel
The opioid epidemic has been a growing public health threat in the United States and Canada for the past 30 years, with alarming and steadily increasing opioid-related mortality rates. Originating with well-intentioned efforts by physicians to relieve pain and suffering in their patients, the source of the opioid epidemic and much of its ammunition continues to be the sales of legally produced pharmaceutical opioids. Although surgeons are increasingly recognizing the important role they can play in mitigating this crisis, the recognition and evaluation of the opioid epidemic in plastic surgery has been lacking...
May 2018: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29693428/luisa-s-ghosts-haunted-legality-and-collective-expressions-of-pain
#10
Amy Krauss
Feminist health care providers have debated the efficacy of the decriminalization of abortion in Mexico City. Luisa, a counselor in a private clinic, suggested that while the law has expanded the visibility of, and access to safe abortion, it has also called forth "other ghosts." In this article, I take Luisa's critical perspective as a starting point for examining ongoing criminalization and moral stigma as forms of haunting that arise in the wake of the Mexico City abortion policy. Drawing on ethnographic research, I explore how Luisa's ghosts materialize in the embodied- affective relations between patients in new legal clinics...
April 25, 2018: Medical Anthropology
https://www.readbyqxmd.com/read/29686145/interpretation-of-do-not-attempt-resuscitation-orders-for-children-requiring-anesthesia-and-surgery
#11
Mary E Fallat, Courtney Hardy
This clinical report addresses the topic of pre-existing do not attempt resuscitation or limited resuscitation orders for children and adolescents undergoing anesthesia and surgery. Pertinent considerations for the clinician include the rights of children, decision-making by parents or legally approved representatives, the process of informed consent, and the roles of surgeon and anesthesiologist. A process of re-evaluation of the do not attempt resuscitation orders, called "required reconsideration," should be incorporated into the process of informed consent for surgery and anesthesia, distinguishing between goal-directed and procedure-directed approaches...
May 2018: Pediatrics
https://www.readbyqxmd.com/read/29677141/thematic-analysis-of-medical-notes-offers-preliminary-insight-into-precipitants-for-asian-suicide-attempters-an-exploratory-study
#12
Carol C Choo, Roger C Ho, André A D Burton
One important dynamic risk factor for suicide assessment includes suicide precipitant. This exploratory study used a qualitative paradigm to look into the themes surrounding precipitants for suicide attempts in Singapore. Medical records related to suicide attempters who were admitted to the emergency department of a large teaching hospital in Singapore over a three year period were subjected to analysis. A total of 666 cases were examined (69.2% females; 63.8% Chinese, 15% Malays, 15.8% Indians), ages ranged from 10 years old to 85 years old (Mean = 29...
April 20, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29672092/from-meaning-to-money-translating-injury-into-dollars
#13
Valerie P Hans, Rebecca K Helm, Valerie F Reyna
Legal systems often require the translation of qualitative assessments into quantitative judgments, yet the qualitative-to-quantitative conversion is a challenging, understudied process. We conducted an experimental test of predictions from a new theory of juror damage award decision making, examining how 154 lay people engaged in the translation process in recommending money damages for pain and suffering in a personal injury tort case. The experiment varied the presence, size, and meaningfulness of an anchor number to determine how these factors influenced monetary award judgments, perceived difficulty, and subjective meaningfulness of awards...
April 2018: Law and Human Behavior
https://www.readbyqxmd.com/read/29669384/-obesity-in-revision-total-knee-arthroplasty-a-systematic-review-and-legal-assessment
#14
Milena M Ploeger, Norbert H Müller, Dieter Christian Wirtz, Hendrik Kohlhof
BACKGROUND: In recent years, the incidence of overweight and obesity has increased in the German population. Thus the number of obese patients treated with primary total joint arthroplasty has also increased. It is therefore predicted that the number of obese patients undergoing revision total joint arthroplasty will also increase. Nevertheless almost every manufacturer of commercially available revision arthroplasty implants states in his product safety guarantee that obesity is a relative or absolute contraindication...
April 18, 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29668039/medical-marijuana-use-in-older-adults
#15
Joshua Briscoe, David Casarett
Symptom management in older adults, including pain and distressing non-pain symptoms, can be challenging. Medications can cause side effects that worsen quality of life or create other symptoms, and polypharmacy itself can be detrimental in older adults. Cannabinoids may offer a way of managing selected symptoms with fewer side effects. Medical marijuana is an important area of study for older adults because of the side effects of other medications. It is also important for Baby Boomers, who are likely to have more experience with marijuana than older adults of previous generations...
May 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29664895/medical-marijuana-users-are-more-likely-to-use-prescription-drugs-medically-and-nonmedically
#16
Theodore L Caputi, Keith Humphreys
OBJECTIVES: Previous studies have found a negative population-level correlation between medical marijuana availability in US states, and trends in medical and nonmedical prescription drug use. These studies have been interpreted as evidence that use of medical marijuana reduces medical and nonmedical prescription drug use. This study evaluates whether medical marijuana use is a risk or protective factor for medical and nonmedical prescription drug use. METHODS: Simulations based upon logistic regression analyses of data from the 2015 National Survey on Drug Use and Health were used to compute associations between medical marijuana use, and medical and nonmedical prescription drug use...
April 17, 2018: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29662957/new-york-physicians-perspectives-and-knowledge-of-the-state-medical-marijuana-program
#17
Alexandra Sideris, Fahad Khan, Alina Boltunova, Germaine Cuff, Christopher Gharibo, Lisa V Doan
Introduction: In 2014, New York (NY) became the 23rd state to legalize medical marijuana (MMJ). The purpose of this survey was to collect data about practicing NY physicians' comfort level, opinions, and experience in recommending or supporting patient use of MMJ. Materials and Methods: An anonymous web-based survey was distributed to medical societies and to academic departments in medical schools within NY. Results: A total of 164 responses were analyzed. Physician participants were primarily located in New York City and surrounding areas...
2018: Cannabis and Cannabinoid Research
https://www.readbyqxmd.com/read/29652682/kratom-an-emerging-drug-of-abuse-a-case-report-of-overdose-and-management-of-withdrawal
#18
Jack Diep, David Tian Chin, Somdatta Gupta, Faraz Syed, Ming Xiong, Jianguo Cheng
Kratom is an herb indigenous to Southeast Asia with psychoactive opioid compounds, often used as a treatment for chronic pain or opiate withdrawal symptoms. It is legally and readily available via Internet sales and has been identified as an emerging drug of abuse in the United States. Kratom use has been associated with psychosis, seizures, and even death. At lower doses, kratom acts as a stimulant, while at higher doses, it produces analgesia and euphoria. Here, we describe the successful management of kratom overdose and withdrawal in a young man with negative toxicology screens...
April 15, 2018: A&A practice
https://www.readbyqxmd.com/read/29624475/access-to-strong-opioid-analgesics-in-the-context-of-legal-and-regulatory-barriers-in-eleven-central-and-eastern-european-countries
#19
Marjolein J M Vranken, Aukje K Mantel-Teeuwisse, Marie-Hélène D B Schutjens, Willem K Scholten, Saskia Jünger, Dr Rer Medic, Hubert G M Leufkens
BACKGROUND: In 2011-2013, >95% of the global opioid analgesics consumption occurred in three regions, accounting for 15% of the world population. Despite abundant literature on barriers to access, little is known on the correlation between actual access to opioid analgesics and barriers to access, including legal and regulatory barriers. OBJECTIVE: This study aimed to evaluate the correlation between access to strong opioid analgesics and barriers to access in national legislation and regulations in 11 central and eastern European countries that participated in the Access to Opioid Medication in Europe (ATOME) project...
April 6, 2018: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/29621089/intense-instantaneous-and-shooting-pain-during-local-anesthesia-for-implant-surgery
#20
Antonio Scarano, Bruna Sinjari, Felice Lorusso, Carmen Mortellaro, Cristian D'Ovidio, Francesco Carinci
Administration of local anesthetics is daily routine for most dental practitioners. Normally, the effect is achieved, and no adverse effects are seen. In this article, the authors describe the complications of immediate, intense and shooting pain, numbness, and marked pallor of the cheek, which occurred during infiltration of a local anesthetic in buccal vestibule infiltration. The patients moved suddenly because of pain and marked pallor of the cheek near the root of the nose and lower eyelid pallor was observed...
April 4, 2018: Journal of Craniofacial Surgery
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