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https://www.readbyqxmd.com/read/29350440/abrupt-burial-imparts-persistent-changes-to-the-bacterial-diversity-of-turbidite-associated-sediment-profiles
#1
B K Harrison, A Myrbo, B E Flood, J V Bailey
The emplacement of subaqueous gravity-driven sediment flows imposes a significant physical and geochemical impact on underlying sediment and microbial communities. Although previous studies have established lasting mineralogical and biological signatures of turbidite deposition, the response of bacteria and archaea within and beneath debris flows remains poorly constrained. Both bacterial cells associated with the underlying sediment and those attached to allochthonous material must respond to substantially altered environmental conditions and selective pressures...
January 19, 2018: Geobiology
https://www.readbyqxmd.com/read/29349034/arthroscopic-microfracture-of-hip-chondral-lesions
#2
H Atil Atilla, T David Luo, Allston J Stubbs
Microfracture of hip chondral lesions has been performed for more than a decade with modified treatment principles and techniques from knee arthroscopy. This note and accompanying video review the pertinent techniques, pearls, and pitfalls of the microfracture procedure in the treatment of hip chondral lesions. After debridement of damaged chondral tissue, the size of the lesion is approximated to determine the number of microfracture holes to create. The working portal may be adjusted based on the site of the lesion...
December 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29348025/pet-mr-imaging-of-malondialdehyde-acetaldehyde-epitopes-with-a-human%C3%A2-antibody-detects-clinically%C3%A2-relevant-atherothrombosis
#3
Max L Senders, Xuchu Que, Young Seok Cho, Calvin Yeang, Hannah Groenen, Francois Fay, Claudia Calcagno, Anu E Meerwaldt, Simone Green, Phuong Miu, Mark E Lobatto, Thomas Reiner, Zahi A Fayad, Joseph L Witztum, Willem J M Mulder, Carlos Pérez-Medina, Sotirios Tsimikas
BACKGROUND: Oxidation-specific epitopes (OSEs) are proinflammatory, and elevated levels in plasma predict cardiovascular events. OBJECTIVES: The purpose of this study was to develop novel positron emission tomography (PET) probes to noninvasively image OSE-rich lesions. METHODS: An antigen-binding fragment (Fab) antibody library was constructed from human fetal cord blood. After multiple rounds of screening against malondialdehyde-acetaldehyde (MAA) epitopes, the Fab LA25 containing minimal nontemplated insertions in the CDR3 region was identified and characterized...
January 23, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29345605/histopathological-evaluation-of-aortic-coarctation-after-conventional-balloon-angioplasty-in-neonates
#4
Atakan Atalay, Aysenur Pac, Tugba Avci, Neslihan İnci Zengin, Nadide Demir Amac, Deniz Eris, Irfan Tasoglu, Mustafa Pac
BACKGROUND: Optimal management strategy for native aortic coarctation in neonates and young infants is still a matter of debate. The surgical procedure, histopathologic research, and clinical outcome in 15 neonates who underwent surgery after successful balloon angioplasty is the basis of this study. METHOD: Between 01 October, 2014 and 01 August, 2017, we enrolled 15 patients with native aortic coarctation for this study. These patients had complications regarding recoarctation, following balloon angioplasty intervention at our institute and other centres...
January 18, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29345271/flocculation-on-a-chip-a-novel-screening-approach-to-determine-floc-growth-rates-and-select-flocculating-agents
#5
Anand N P Radhakrishnan, Marco P C Marques, Matthew J Davies, Brian O'Sullivan, Daniel G Bracewell, Nicolas Szita
Flocculation is a key purification step in cell-based processes for the food and pharmaceutical industry where the removal of cells and cellular debris is aided by adding flocculating agents. However, finding the best suited flocculating agent and optimal conditions to achieve rapid and effective flocculation is a non-trivial task. In conventional analytical systems, turbulent mixing creates a dynamic equilibrium between floc growth and breakage, constraining the determination of floc formation rates. Furthermore, these systems typically rely on end-point measurements only...
January 18, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29344915/mechanistic-investigation-of-visible-light-driven-photocatalytic-inactivation-of-e-coli-by-ag-agcl-znfe2o4
#6
Akhanda Raj Upreti, Nirina Khadgi, Yi Li
In this study, photocatalytic inactivation of Escherichia coli was investigated over magnetic nanocomposite Ag-AgCl/ZnFe2O4. The nanocomposite demonstrated efficient photocatalytic activity by complete inactivation of the bacteria within 60 min of visible light irradiation. The anions HPO42- and SO42- were found to play the most important role in the inhibition of photocatalytic inactivation of E. coli. A systematic investigation of mechanism of photocatalytic bacterial inactivation was carried out based on cell membrane injury test, scanning electron microscopy (SEM) of bacterial morphology changes, Fourier transform infrared (FTIR) spectroscopy of E...
January 17, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29344565/a-novel-method-of-endoscopic-assisted-esophageal-clearance-in-advanced-achalasia
#7
Shinwa Tanaka, Fumiaki Kawara, Takashi Toyonaga, Robert Bechara, Namiko Hoshi, Hirofumi Abe, Yoshiko Ohara, Tsukasa Ishida, Yoshinori Morita, Eiji Umegaki
Background and study aims : In order to perform peroral endoscopic myotomy (POEM) safely, retained liquid and food debris must be removed before the procedure is started. We developed a novel technique using a super-slim gastroscope, and a gastric tube to remove retained food debris in achalasia patients. In this study, the safety and efficacy of this novel technique were investigated. Patients and methods : Eleven patients with achalasia were enrolled in this study and underwent this novel method for esophageal clearance...
January 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29343757/the-early-conversion-of-deep-sea-wood-falls-into-chemosynthetic-hotspots-revealed-by-in-situ-monitoring
#8
D Kalenitchenko, E Péru, L Contreira Pereira, C Petetin, P E Galand, N Le Bris
Wood debris on the ocean floor harbor flourishing communities, which include invertebrate taxa thriving in sulfide-rich habitats belonging to hydrothermal vent and methane seep deep-sea lineages. The formation of sulfidic niches from digested wood material produced by woodborers has been known for a long time, but the temporal dynamics and sulfide ranges encountered on wood falls remains unknown. Here, we show that wood falls are converted into sulfidic hotpots, before the colonization by xylophagaid bivalves...
January 17, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29342855/introduction-to-state-estimation-of-high-rate-system-dynamics
#9
Jonathan Hong, Simon Laflamme, Jacob Dodson, Bryan Joyce
Engineering systems experiencing high-rate dynamic events, including airbags, debris detection, and active blast protection systems, could benefit from real-time observability for enhanced performance. However, the task of high-rate state estimation is challenging, in particular for real-time applications where the rate of the observer's convergence needs to be in the microsecond range. This paper identifies the challenges of state estimation of high-rate systems and discusses the fundamental characteristics of high-rate systems...
January 13, 2018: Sensors
https://www.readbyqxmd.com/read/29342012/diffuse-chorioretinopathy-without-serous-detachment-associated-with-cardiac-transplantation
#10
Michael F Marmor
PURPOSE: To analyze an unusual case of widespread chorioretinopathy after cardiac transplantation for its potential etiology and clinical significance. METHODS: Clinical examinations included widefield and macular color and fundus autofluorescence photography, spectral domain optical coherence tomography, fluorescein angiography and indocyanine green angiography, full-field electroretinography, and Goldmann visual fields. PATIENT: A 44-year-old Hispanic woman was referred to rule out retinitis pigmentosa...
January 16, 2018: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29342010/the-ever-expanding-saga-of-the-proprotein-convertases-and-their-roles-in-body-homeostasis-emphasis-on-novel-proprotein-convertase-subtilisin-kexin-number-9-functions-and-regulation
#11
Nabil G Seidah, Michel Chrétien, Majambu Mbikay
PURPOSE OF REVIEW: The nine members of the proprotein convertase family play major physiological roles during development and in the adult, and their dysregulation leads to various diseases. The primary objective of this article is to review recent findings on the clinical importance of some of these convertases concentrating mostly on PCSK9, the ninth member of the convertase family. This includes the transcriptional and translational regulation of PCSK9, its ability to enhance the degradation of LDL receptor (LDLR), and the implication of PCSK9 in inflammation and sepsis...
January 15, 2018: Current Opinion in Lipidology
https://www.readbyqxmd.com/read/29341456/iron-pill-aspiration-cytologic-and-histologic-findings-of-a-potential-life-threatening-airway-injury-a-case-report-and-literature-review
#12
Vanessa Henriques, Diogo Costa Santos, Graça Lérias, Lucília Cáceres Monteiro
Iron pill-induced injury of bronchial mucosa is a complication following accidental aspiration of an iron tablet. Oral iron supplementation is a common therapy, particularly among advanced-age patients, who are more prone to aspiration. However, iron pill aspiration has been rarely reported in the literature, usually under the format of short case reports, with only 32 cases published in the literature. The cytologic features suspicious for this rare but potentially lethal entity have been seldom described...
January 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29340649/optic-nerve-regeneration-after-crush-remodels-the-injury-site-molecular-insights-from-imaging-mass-spectrometry
#13
David T Stark, David M G Anderson, Jacky M K Kwong, Nathan Heath Patterson, Kevin L Schey, Richard M Caprioli, Joseph Caprioli
Purpose: Mammalian central nervous system axons fail to regenerate after injury. Contributing factors include limited intrinsic growth capacity and an inhibitory glial environment. Inflammation-induced optic nerve regeneration (IIR) is thought to boost retinal ganglion cell (RGC) intrinsic growth capacity through progrowth gene expression, but effects on the inhibitory glial environment of the optic nerve are unexplored. To investigate progrowth molecular changes associated with reactive gliosis during IIR, we developed an imaging mass spectrometry (IMS)-based approach that identifies discriminant molecular signals in and around optic nerve crush (ONC) sites...
January 1, 2018: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29339337/adsorption-of-perfluoroalkyl-substances-on-microplastics-under-environmental-conditions
#14
Marta Llorca, Gabriella Schirinzi, Mònica Martínez, Damià Barceló, Marinella Farré
Plastic debris has become an environmental problem during recent years. Among the plastic debris, microplastics (<5 mm; MPLs) imply an extra problem due to their capacity to enter into the fauna through ingestion. In this work, we study the capacity of three MPLs, that include high-density polyethylene (HDPE), polystyrene (PS) and polystyrene carboxylate (PS-COOH), to sorb 18 perfluoroalkyl substances (PFASs; including carboxylic acids, sulphonates and one sulphonamide) from the surrounding waters (freshwater and seawater)...
January 12, 2018: Environmental Pollution
https://www.readbyqxmd.com/read/29339190/systemic-and-local-toxicity-of-metal-particles-released-from-hip-prostheses-a-review-of-experimental-approaches
#15
REVIEW
Divya Rani Bijukumar, Abhijith Segu, Júlio Cesar Matias de Souza, XueJun Li, Mark Barba, Louis Mercuri, Joshua Jacobs, Mathew Thoppil Mathew
Despite the technological improvements in orthopedic joint replacement implants, wear and corrosion products associated with the metal components of these implants may result in adverse local tissue and perhaps systemic reactions and toxicities. The current review encompasses a literature review of the local and systemic toxicity studies concerning the effect of CoCrMo wear particles released from wear and corrosion of orthopedic implants and prostheses. Release of metallic debris is mainly in the form of micro- and nano-particles, ions of different valences, and oxides composed of Co and Cr...
January 12, 2018: Nanomedicine: Nanotechnology, Biology, and Medicine
https://www.readbyqxmd.com/read/29337627/increased-incidence-of-enterococcal-infection-in-nonviable-broiler-chicken-embryos-in-western-canadian-hatcheries-as-detected-by-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry
#16
Ruwani Karunarathna, Shelly Popowich, Morgan Wawryk, Betty Chow-Lockerbie, Khawaja Ashfaque Ahmed, Chenfang Yu, Mengying Liu, Kalhari Goonewardene, Thushari Gunawardana, Shanika Kurukulasuriya, Ashish Gupta, Philip Willson, Neil Ambrose, Musangu Ngeleka, Susantha Gomis
The emergence of enterococcal infections in neonatal broiler chickens in the poultry industry has become common in many countries, including Canada. The objective of this study was to examine the bacterial infections in nonviable broiler chicken embryos in three western Canadian poultry hatcheries using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The pattern of embryo mortality that occurred during incubation and the breakout analysis results were similar in all three hatcheries...
December 2017: Avian Diseases
https://www.readbyqxmd.com/read/29336992/schwann-cell-lamellipodia-regulate-cell-cell-interactions-and-phagocytosis
#17
Johana Tello Velasquez, James A St John, Lynn Nazareth, Jenny A K Ekberg
Lamellipodia in Schwann cells (SCs) are crucial for myelination, but their other biological functions remain largely uncharacterised. Two types of lamellipodia exist in SCs: axial lamellipodia at the outermost edge of the cell processes, and radial lamellipodia appearing peripherally along the entire cell. We have previously shown that radial lamellipodia on olfactory glia (olfactory ensheathing cells; OECs) promote cell-cell adhesion, contact-mediated migration and phagocytosis. Here we have investigated whether lamellipodia in SCs have similar roles...
January 11, 2018: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/29336950/daratumumab-therapeutic-asset-biological-trap
#18
V Deneys, C Thiry, A Frelik, C Debry, B Martin, C Doyen
OBJECTIVES: Recently, daratumumab has been included in the therapeutic strategies for myeloma patients. This molecule is an antibody directed against CD38, strongly expressed on plasma cells. Nevertheless, as CD38 is also present on erythrocyte membrane, daratumumab interferes with immunohaematological tests, complicating the selection of compatible blood. METHODS: A total of 14 patients treated by daratumumab have been followed in our transfusion laboratory. Among them, 11 have been transfused...
January 11, 2018: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
https://www.readbyqxmd.com/read/29336824/trait-based-characterization-of-species-transported-on-japanese-tsunami-marine-debris-effect-of-prior-invasion-history-on-trait-distribution
#19
Jessica A Miller, Reva Gillman, James T Carlton, Cathryn Clarke Murray, Jocelyn C Nelson, Michio Otani, Gregory M Ruiz
Nearly 300 coastal marine species collected from >630 debris items from the 2011 Great East Japan earthquake and tsunami have landed alive along the North American Pacific coast and the Hawaiian Archipelago. We synthesized life history, environmental, and distributional traits for 103 of these species and compared species with (n=30) and without (n=62) known invasion histories. The species represent 12 phyla, and Mollusca, Crustacea, and Bryozoa accounted for 71 of the 103 species. The majority are native to the Northwest Pacific and the Central Indo-Pacific...
January 11, 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29333941/intraoperative-complications-and-mid-term-follow-up-of-large-diameter-head-metal-on-metal-total-hip-arthroplasty-and-hip-resurfacing-arthroplasty
#20
S S A Miettinen, T J Mäkinen, K Mäkelä, H Huhtala, J S Kettunen, V Remes
BACKGROUND AND AIMS: Large-diameter head total hip arthroplasty and hip resurfacing arthroplasty were popular in Finland from 2000 to 2012 for the treatment of hip osteoarthritis. The aim of this retrospective study was to investigate the mid-term survival of large-diameter head total hip arthroplasty patients operated on in three university hospitals and to compare these results to the survival of hip resurfacing arthroplasty patients. MATERIAL AND METHODS: A total of 3860 hip arthroplasties (3029 large-diameter head total hip arthroplasties in 2734 patients and 831 hip resurfacing arthroplasties in 757 patients) were operated on between January 2004 and December 2009...
January 1, 2018: Scandinavian Journal of Surgery: SJS
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