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https://www.readbyqxmd.com/read/29775448/pyonephrosis-as-the-first-symptom-of-congenital-hydronephrosis-in-a-6-year-old-girl
#1
Teresa Dudek-Warchoł, Stanisław Warchoł, Przemysław Bombiński, Krzysztof Toth, Agnieszka Szmigielska, Garżyna Krzemień
Pyonephrosis in the course of hydronephrosis usually provides to total or near-total loss of renal function. In adults pyonephrosis usually results from urolithiasis. In children usually congenital urinary tract anomalies are present as contributing factors. CASE REPORT: 6-year old girl was admitted to the hospital because of 2-day history of high fever, abdominal pain, progressive deterioration of general condition and ultrasonographically (US) detected left hydronephrosis. US on admission showed grossly dilated left renal collecting system together with extensive echogenic debris and laboratory tests highly elevated inflammatory markers...
April 23, 2018: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29775361/asperity-level-origins-of-transition-from-mild-to-severe-wear
#2
Ramin Aghababaei, Tobias Brink, Jean-François Molinari
Wear is the inevitable damage process of surfaces during sliding contact. According to the well-known Archard's wear law, the wear volume scales with the real contact area and as a result is proportional to the load. Decades of wear experiments, however, show that this relation only holds up to a certain load limit, above which the linearity is broken and a transition from mild to severe wear occurs. We investigate the microscopic origins of this breakdown and the corresponding wear transition at the asperity level...
May 4, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29775103/shoot-litter-breakdown-and-zinc-dynamics-of-an-aquatic-plant-schoenoplectus-californicus
#3
Silvana Arreghini, Laura de Cabo, Roberto José María Serafini, Alicia Fabrizio de Iorio
Decomposition of plant debris is an important process in determining the structure and function of aquatic ecosystems. The aims were to find a mathematic model fitting the decomposition process of Schoenoplectus californicus shoots containing different Zn concentrations; compare the decomposition rates; and assess metal accumulation/mobilization during decomposition. A litterbag technique was applied with shoots containing three levels of Zn: collected from an unpolluted river (RIV) and from experimental populations at low (LoZn) and high (HiZn) Zn supply...
July 3, 2018: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/29773665/hypersensitivity-pneumonitis-and-acute-respiratory-distress-syndrome-from-e-cigarette-use
#4
Casey G Sommerfeld, Daniel J Weiner, Andrew Nowalk, Allyson Larkin
Electronic cigarette (e-cigarette) use, or "vaping," is gaining widespread popularity as an alternative to conventional cigarettes among adolescents. Little is known of the health risks of e-cigarette use, especially in children and adolescents. We present a Case Report of a previously healthy 18-year-old woman who presented with dyspnea, cough, and pleuritic chest pain after e-cigarette use. She developed respiratory failure with hypoxia and was intubated, and ultimately met diagnostic criteria for acute respiratory distress syndrome...
May 17, 2018: Pediatrics
https://www.readbyqxmd.com/read/29773443/sequential-webcam-monitoring-and-modeling-of-marine-debris-abundance
#5
Shin'ichiro Kako, Atsuhiko Isobe, Tomoya Kataoka, Kei Yufu, Shuto Sugizono, Charlie Plybon, Thomas A Murphy
The amount of marine debris washed ashore on a beach in Newport, Oregon, USA was observed automatically and sequentially using a webcam system. To investigate potential causes of the temporal variability of marine debris abundance, its time series was compared with those of satellite-derived wind speeds and sea surface height off the Oregon coast. Shoreward flow induced by downwelling-favorable southerly winds increases marine debris washed ashore on the beach in winter. We also found that local sea-level rise caused by westerly winds, especially at spring tide, moved the high-tide line toward the land, so that marine debris littered on the beach was likely to re-drift into the ocean...
May 14, 2018: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/29773173/gene-expression-in-adverse-reaction-to-metal-debris-around-metal-on-metal-arthroplasty-an-rna-seq-based-study
#6
Antti Pemmari, Tiina Leppänen, Erja-Leena Paukkeri, Antti Eskelinen, Teemu Moilanen, Eeva Moilanen
Joint replacement surgery is a standard treatment of advanced osteoarthritis (OA). Since 2000, cobalt-chromium (CoCr) metal-on-metal (MoM) implants were widely used in hip arthroplasties. Some patients developed "adverse reaction to metal debris" (ARMD) around the prosthesis, resulting in a need for revision surgery. In the present study, we addressed the pathogenesis of ARMD by genome-wide expression analysis. Pseudosynovial ARMD tissue was obtained from revision surgery of Articular Surface Replacement (ASR, DePuy, Warsaw, IN, USA) hip arthroplasties...
July 2018: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/29768492/association-between-periprosthetic-tissue-metal-content-whole-blood-and-synovial-fluid-metal-ion-levels-and-histopathological-findings-in-patients-with-failed-metal-on-metal-hip-replacement
#7
Lari Lehtovirta, Aleksi Reito, Jyrki Parkkinen, Sirpa Peräniemi, Jouko Vepsäläinen, Antti Eskelinen
Adverse Reaction to Metal Debris (ARMD) is a major cause of implant failure leading to revision surgery in patients with metal-on-metal (MoM) hip arthroplasties. However, the pathogenesis and its association to implant wear are poorly understood and previous studies have yielded discrepant results. We sought to investigate the associations between histological findings, whole blood and synovial fluid metal ion concentrations and periprosthetic tissue metal concentrations in patients with MoM total hip replacements and hip resurfacings revised for ARMD...
2018: PloS One
https://www.readbyqxmd.com/read/29768091/effect-of-830-nm-diode-laser-irradiation-of-root-canal-on-bond-strength-of-metal-and-fiber-post
#8
Claudia Strefezza, Marcello Magri Amaral, José Quinto, Sheila Cynthia Gouw-Soares, Claudia Bianchi Zamataro, Denise Maria Zezell
OBJECTIVE AND BACKGROUND: The correct selections of the cementing agent, the endodontic post material and placement protocol are critical to provide an increased longevity of the teeth that went through endodontic treatment. The irradiation with diode laser before post cementation, can promote an antimicrobial effect. However, there is a lack of information about the effect of 830 nm diode laser on the post bond strength. This study analyzed the effect of dentin root canal irradiation with high-intensity diode laser, at 830 nm, operating in continuous or pulsed mode, on the retention of metal or fiber posts, cemented with self-etching resinous composite (Panavia F) and zinc phosphate cement (ZnPO4 )...
May 16, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29765661/testing-the-assumptions-of-the-pyrodiversity-begets-biodiversity-hypothesis-for-termites-in-semi-arid-australia
#9
Hayley Davis, Euan G Ritchie, Sarah Avitabile, Tim Doherty, Dale G Nimmo
Fire shapes the composition and functioning of ecosystems globally. In many regions, fire is actively managed to create diverse patch mosaics of fire-ages under the assumption that a diversity of post-fire-age classes will provide a greater variety of habitats, thereby enabling species with differing habitat requirements to coexist, and enhancing species diversity (the pyrodiversity begets biodiversity hypothesis). However, studies provide mixed support for this hypothesis. Here, using termite communities in a semi-arid region of southeast Australia, we test four key assumptions of the pyrodiversity begets biodiversity hypothesis (i) that fire shapes vegetation structure over sufficient time frames to influence species' occurrence, (ii) that animal species are linked to resources that are themselves shaped by fire and that peak at different times since fire, (iii) that species' probability of occurrence or abundance peaks at varying times since fire and (iv) that providing a diversity of fire-ages increases species diversity at the landscape scale...
April 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29761404/genetic-models-of-macrophage-depletion
#10
Li Hua, Jiayuan Shi, Leonard D Shultz, Guangwen Ren
Macrophages are a heterogeneous population of innate immune cells and are distributed in most adult tissues. Certain tissue-resident macrophages with a prenatal origin, together with postnatal monocyte-derived macrophages, serve as the host scavenger system to eliminate invading pathogens, malignant cells, senescent cells, dead cells, cellular debris, and other foreign substances. As a key member of the mononuclear phagocyte system, macrophages play essential roles in regulation of prenatal development, tissue homeostasis, and disease progression...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29761388/isolation-and-identification-of-interstitial-macrophages-from-the-lungs-using-different-digestion-enzymes-and-staining-strategies
#11
Shaikh M Atif, Sophie L Gibbings, Claudia V Jakubzick
Interstitial macrophages (IMs) are present in multiple organs. Although there is limited knowledge of the unique functional role IM subtypes play, macrophages, in general, are known for their contribution in homeostatic tissue maintenance and inflammation such as clearing pathogens and debris and secreting inflammatory mediators and growth factors. IM subtypes have been identified in the heart, skin, and gut, and more recently we identified three distinct IMs in the lung. IMs express on their surface high levels of MerTK, CD64, and CD11b, with differences in CD11c, CD206, and MHC II expression, and referred to the three pulmonary IM subtypes as IM1 (CD11clo CD206+ MHCIIlo ), IM2 (CD11clo CD206+ MHCIIhi ), and IM3 (CD11chi CD206lo MHCIIhi )...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29758340/traditional-mongolian-medicine-eerdun-wurile-improves-stroke-recovery-through-regulation-of-gene-expression-in-rat-brain
#12
Saren Gaowa, Narisi Bao, Man Da, Qiburi Qiburi, Tsogzolmaa Ganbold, Lu Chen, Altanzul Altangerel, Temuqile Temuqile, Huricha Baigude
ETHNOPHARMACOLOGICAL RELEVANCE: Eerdun Wurile (EW) is one of the key Mongolian medicines for treatment of neurological and cardiological disorders. EW is ranked most regularly used Mongolian medicine in clinic. Components of EW which mainly originate from natural products are well defined and are unique to Mongolian medicine. AIM OF THE STUDY: Although the recipe of EW contains known neuroactive chemicals originated from plants, its mechanism of action has never been elucidated at molecular level...
May 11, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29756511/surface-integrity-of-polyethylene-liners-following-trunnionosis-of-a-dual-modular-neck-total-hip-implant
#13
Ben Gi Spiegelberg, Brent A Lanting, James L Howard, Matthew G Teeter, Douglas Dr Naudie
BACKGROUND: There has been a trend in the evolution of total hip arthroplasty towards increased modularity; with this increase in modularity come some potentially harmful consequences. Modularity at the neck shaft junction has been linked to corrosion, adverse reaction to metal debris and pseudotumour formation. AIM: The aim of this retrieval study is to assess whether the surface integrity of the polyethylene (PE) liner is affected by metal wear debris in a single implant design series of THA revised for trunnionosis...
May 1, 2018: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/29755473/differential-effect-of-viable-versus-necrotic-neutrophils-on-mycobacterium-tuberculosis-growth-and-cytokine-induction-in-whole-blood
#14
David M Lowe, Julie Demaret, Nonzwakazi Bangani, Justine K Nakiwala, Rene Goliath, Katalin A Wilkinson, Robert J Wilkinson, Adrian R Martineau
Neutrophils exert both positive and negative influences on the host response to tuberculosis, but the mechanisms by which these differential effects are mediated are unknown. We studied the impact of live and dead neutrophils on the control of Mycobacterium tuberculosis using a whole blood bioluminescence-based assay, and assayed supernatant cytokine concentrations using Luminex™ technology and ELISA. CD15+ granulocyte depletion from blood prior to infection with M. tuberculosis -lux impaired control of mycobacteria by 96 h, with a greater effect than depletion of CD4+, CD8+, or CD14+ cells ( p  < 0...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29754299/high-throughput-nir-spectroscopic-nirs-detection-of-microplastics-in-soil
#15
Andrea Paul, Lukas Wander, Roland Becker, Caroline Goedecke, Ulrike Braun
The increasing pollution of terrestrial and aquatic ecosystems with plastic debris leads to the accumulation of microscopic plastic particles of still unknown amount. To monitor the degree of contamination, analytical methods are urgently needed, which help to quantify microplastics (MP). Currently, time-costly purified materials enriched on filters are investigated both by micro-infrared spectroscopy and/or micro-Raman. Although yielding precise results, these techniques are time consuming, and are restricted to the analysis of a small part of the sample in the order of few micrograms...
May 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29753038/inspection-of-endoscope-instrument-channels-after-reprocessing-using-a-prototype-borescope
#16
Adarsh M Thaker, Stephen Kim, Alireza Sedarat, Rabindra R Watson, V Raman Muthusamy
BACKGROUND AND AIMS: Visual inspection of the instrument channel has been proposed as a quality assurance step during endoscope reprocessing. However, the nature and severity of findings in a broad array of endoscopes (gastroscopes, colonoscopes, duodenoscopes, and echoendoscopes) after systemic implementation of an inspection protocol remain unknown. In addition, a study using borescope inspection in upper endoscopes and colonoscopes raised concerns about persistent simethicone residue despite full reprocessing...
May 9, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29751654/biodegradation-of-di-2-ethylhexyl-phthalate-by-rhodococcus-ruber-yc-yt1-in-contaminated-water-and-soil
#17
Ting Yang, Lei Ren, Yang Jia, Shuanghu Fan, Junhuan Wang, Jiayi Wang, Ruth Nahurira, Haisheng Wang, Yanchun Yan
Di-(2-ethylehxyl) phthalate (DEHP) is one of the most broadly representative phthalic acid esters (PAEs) used as a plasticizer in polyvinyl chloride (PVC) production, and is considered to be an endocrine-disrupting chemical. DEHP and its monoester metabolites are responsible for adverse effects on human health. An efficient DEHP-degrading bacterial strain Rhodococcus ruber YC-YT1, with super salt tolerance (0⁻12% NaCl), is the first DEHP-degrader isolated from marine plastic debris found in coastal saline seawater...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29751408/can-beaver-impact-promote-river-renaturalization-the-example-of-the-raba-river-southern-poland
#18
Elżbieta Gorczyca, Kazimierz Krzemień, Mateusz Sobucki, Krzysztof Jarzyna
The European beaver (Castor fiber) was reintroduced in the Polish Carpathians in the 1980s after a few centuries of absence. It gradually colonized suitable habitats in the Raba River valley and elsewhere. The question arises as to whether beaver activity can play a role in the local improvement of hydromorphological conditions and spontaneous renaturalization of the Raba River channel. Field surveys were performed in morphodynamically and structurally homogeneous reaches of the river. Traces of beaver activity were identified and used to estimate the studied beaver population...
February 15, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29749475/mir-125a-induces-apoptosis-metabolism-disorder-and-migrationimpairment-in-pancreatic-cancer-cells-by-targeting-mfn2-related-mitochondrial-fission
#19
Lichao Pan, Lin Zhou, Weijia Yin, Jia Bai, Rong Liu
Mitochondrial fission is important for the development and progression of pancreatic cancer (PC). However, little is known regarding its role in pancreatic cancer apoptosis, metabolism and migration. In the current study, the mechanism by which mitochondrial fission modifies the biological characteristics of PC was explored. MicroRNA‑125a (miR‑125a) had the ability to inhibit mitochondrial fission and contributed to cellular survival. Suppressed mitochondrial fission led to a reduction in mitochondrial debris, preserved the mitochondrial membrane potential, inhibited mitochondrial permeability transition pore opening, ablated cytochrome c leakage into the cytoplasm and reduced the pro‑apoptotic protein contents, finally blocking mitochondria related apoptosis pathways...
April 26, 2018: International Journal of Oncology
https://www.readbyqxmd.com/read/29748788/biological-response-of-an-in-vitro-human-3d-lung-cell-model-exposed-to-brake-wear-debris-varies-based-on-brake-pad-formulation
#20
Hana Barosova, Savvina Chortarea, Pavlina Peikertova, Martin J D Clift, Alke Petri-Fink, Jana Kukutschova, Barbara Rothen-Rutishauser
Wear particles from automotive friction brake pads of various sizes, morphology, and chemical composition are significant contributors towards particulate matter. Knowledge concerning the potential adverse effects following inhalation exposure to brake wear debris is limited. Our aim was, therefore, to generate brake wear particles released from commercial low-metallic and non-asbestos organic automotive brake pads used in mid-size passenger cars by a full-scale brake dynamometer with an environmental chamber simulating urban driving and to deduce their potential hazard in vitro...
May 10, 2018: Archives of Toxicology
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