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https://www.readbyqxmd.com/read/28190544/treatment-of-steroid-resistant-hashimoto-encephalopathy-with-misidentification-delusions-and-catatonia
#1
Yujin Lee, Ellen M House
No abstract text is available yet for this article.
October 27, 2016: Psychosomatics
https://www.readbyqxmd.com/read/28141622/5-ht6-receptor-antagonist-as-an-adjunct-treatment-targeting-residual-symptoms-in-patients-with-schizophrenia-unexpected-sex-related-effects-double-blind-placebo-controlled-trial
#2
Margarita Morozova, Denis Burminskiy, George Rupchev, Taissia Lepilkina, Sergey Potanin, Allan Beniashvili, Yan Lavrovsky, Natalia Vostokova, Alexander Ivaschenko
BACKGROUND: Treating patients who experience residual psychotic symptoms during remission of schizophrenia remains one of the most challenging problems. The mechanisms underlying these symptoms differ from those of acute hallucinations and delusions. 5-HT6 receptor antagonists have been considered promising agents in treatment of residual psychotic symptoms and cognitive dysfunction. The aim of the study was to assess the efficacy of a selective 5-HT6 inhibitor Avisetron in the reduction of residual psychotic symptoms in patients with schizophrenia on stable antipsychotic therapy...
January 30, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28138403/clozapine-in-a-patient-with-treatment-resistant-schizophrenia-and-hypertrophic-cardiomyopathy-a-case-report
#3
Asiel Yair Adan Sanchez, Jessica J Foster, Carla M Plymen, Sukhi Shergill
BACKGROUND: There is currently limited experience in the initiation and maintenance of clozapine for treatment-resistant psychosis in adults with established structural heart disease. These complex patients require close supervision and liaison between colleagues. Here we present the successful experience of treating one such patient within our service and describe a monitoring plan to ensure that these treatments can be provided both safely and effectively. CASE PRESENTATION: A 36-year-old man with treatment-resistant schizophrenia and known hypertrophic cardiomyopathy (HCM) was admitted to a specialist unit for a trial of clozapine...
November 2016: BJPsych Open
https://www.readbyqxmd.com/read/28116236/the-neural-correlates-and-clinical-characteristics-of-psychosis-in-the-frontotemporal-dementia-continuum-and-the-c9orf72-expansion
#4
Emma M Devenney, Ramon Landin-Romero, Muireann Irish, Michael Hornberger, Eneida Mioshi, Glenda M Halliday, Matthew C Kiernan, John R Hodges
OBJECTIVE: This present study aims to address the gap in the literature regarding the severity and underlying neural correlates of psychotic symptoms in frontotemporal dementia with and without the C9orf72 gene expansion. METHODS: Fifty-six patients with behavioural variant frontotemporal dementia (20 with concomitant amyotrophic lateral sclerosis) and 23 healthy controls underwent neuropsychological assessments, detailed clinical interview for assessment of psychosis symptoms, brain MRI and genetic testing...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28114093/-cotard-s-syndrome-case-report-and-a-brief-review-of-literature
#5
N P Moschopoulos, S Kaprinis, J Nimatoudis
The term "Cotard's syndrome" is used to describe a number of clinical features, mostly hypochondriac and nihilistic delusions, the most characteristic of which are the ideas "I am dead" and "my internal organs do not exist". Besides, anxious and depressed mood, delusions of damnation, possession and immortality, suicidal and self-mutilating behavior are included. The first description of the syndrome was made in 1880 by Cotard, who presented the case of a female patient in a lecture. He originally named it "hypochondriac delusion", and some years later "delusion of negations", while it was named "Cotard delusion" after his death...
October 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/28106066/the-psychosis-spectrum-in-parkinson-disease
#6
REVIEW
Dominic H Ffytche, Byron Creese, Marios Politis, K Ray Chaudhuri, Daniel Weintraub, Clive Ballard, Dag Aarsland
In 2007, the clinical and research profile of illusions, hallucinations, delusions and related symptoms in Parkinson disease (PD) was raised with the publication of a consensus definition of PD psychosis. Symptoms that were previously deemed benign and clinically insignificant were incorporated into a continuum of severity, leading to the rapid expansion of literature focusing on clinical aspects, mechanisms and treatment. Here, we review this literature and the evolving view of PD psychosis. Key topics include the prospective risk of dementia in individuals with PD psychosis, and the causal and modifying effects of PD medication...
February 2017: Nature Reviews. Neurology
https://www.readbyqxmd.com/read/28092756/effects-of-assisted-outpatient-treatment-and-health-care-services-on-psychotic-symptoms
#7
Andres R Schneeberger, Christian G Huber, Undine E Lang, Kristina H Muenzenmaier, Dorothy Castille, Matthias Jaeger, Azizi Seixas, Julia Sowislo, Bruce G Link
RATIONALE: An ongoing debate concerns acceptability, benefits, and shortcomings of coercive treatment such as assisted outpatient treatment (AOT). The hypothesis that involuntary commitment to outpatient treatment may lead to a better clinical outcome for a subgroup of persons with severe mental illness (SMI) is controversial. Nonetheless, positive effects of AOT may be mediated by an increased availability of healthcare resources or increased service use. OBJECTIVE: The purpose of the present study is to evaluate the course of delusions, hallucinations, and negative symptoms among patients with SMI receiving AOT compared to patients receiving non-compulsory treatment (NCT)...
January 6, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28065176/behavioural-and-psychological-symptoms-in-general-hospital-patients-with-dementia-distress-for-nursing-staff-and-complications-in-care-results-of-the-general-hospital-study
#8
J B Hessler, M Schäufele, I Hendlmeier, M N Junge, S Leonhardt, J Weber, H Bickel
AIMS: Little is known about how behavioural and psychological symptoms of dementia (BPSD) manifest in the general hospital. The aim was to examine the frequency of BPSD in general hospitals and their associations with nursing staff distress and complications in care. METHODS: Cross-sectional representative study with 1469 patients aged ≥65, including 270 patients with dementia, of 33 randomly selected general hospitals in Germany. BPSD and complications were reported by nurses...
January 9, 2017: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/28056884/secondary-psychotic-features-in-refugees-diagnosed-with-post-traumatic-stress-disorder-a-retrospective-cohort-study
#9
Mette Nygaard, Charlotte Sonne, Jessica Carlsson
BACKGROUND: A substantial amount of refugees (10-30%) suffer from Post-Traumatic Stress Disorder (PTSD). In Denmark there are different facilities specialised in psychiatric treatment of trauma-affected refugees. A previously published case report from such a facility in Denmark shows that some patients suffer from secondary psychotic symptoms alongside their PTSD. The aim of this study was to illustrate the characteristics and estimate the prevalence of psychotic features in a clinical population of trauma-affected refugees with PTSD...
January 5, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28041541/-electroconvulsive-therapy-is-efficient-in-treating-cotard-s-syndrome
#10
Tatiana Mamaeva, Ditte Sigaard Christensen, Connie Thurøe Nielsen
Cotard's syndrome is a rare psychiatric disorder characterized by nihilistic delusions in which the patient is convinced that death has occurred or the internal organs have perished. The treatment of Cotard's syndrome requires monotherapy or combination therapy with antidepressants, antipsychotics, mood-stabilizing drugs or electroconvulsive treatment (ECT). We describe a woman with severe depression and Cotard's syndrome who responded well to ECT. This case is not only an example of a patient with Cotard's syndrome, but also an example of how quickly and severely a delirium can develop...
December 19, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28003827/when-the-patient-believes-that-the-organs-are-destroyed-manifestation-of-cotard-s-syndrome
#11
Leonardo Machado, Luiz Evandro de Lima Filho, Liliane Machado
Cotard's Syndrome (CS) is a rare clinical event described for the first time in 1880 by the neurologist and psychiatrist Jules Cotard and characterized by negation delusions (or nihilists). Immortality and hypochondriac delusions are also typical. Nowadays, it is known that CS can be associated with many neuropsychiatric conditions. In this article, we describe the case of a patient that believed not having more organs and having the body deformed and whose CS was associated with a bigger depressive disorder...
2016: Case Reports in Medicine
https://www.readbyqxmd.com/read/27995564/a-review-of-the-functional-and-anatomical-default-mode-network-in-schizophrenia
#12
REVIEW
Mao-Lin Hu, Xiao-Fen Zong, J John Mann, Jun-Jie Zheng, Yan-Hui Liao, Zong-Chang Li, Ying He, Xiao-Gang Chen, Jin-Song Tang
Schizophrenia is a severe mental disorder characterized by impaired perception, delusions, thought disorder, abnormal emotion regulation, altered motor function, and impaired drive. The default mode network (DMN), since it was first proposed in 2001, has become a central research theme in neuropsychiatric disorders, including schizophrenia. In this review, first we define the DMN and describe its functional activity, functional and anatomical connectivity, heritability, and inverse correlation with the task positive network...
December 19, 2016: Neuroscience Bulletin
https://www.readbyqxmd.com/read/27940386/could-panss-be-a-useful-tool-in-the-determining-of-the-stages-of-schizophrenia-a-clinically-operational-approach
#13
Elena Dragioti, Tobias Wiklund, Melina Siamouli, Katerina Moutou, Konstantinos N Fountoulakis
Staging in schizophrenia might be an important approach for the better treatment and rehabilitation of patients. The purpose of this study was to empirically devise a staging approach in a sample of stabilized patients with schizophrenia. One hundred and seventy patients aged ≥18 years (mean = 40.7, SD = 11.6) diagnosed by DSM-5 criteria were evaluated with the Positive and Negative Syndrome Scale (PANSS). Principal components analysis (PCA) with varimax rotation was used. The model was examined in the total sample and separately across a hypothesized stage of illness based on three age groups and between the two sexes...
March 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/27869872/-towards-dsm-5-1-proposals-for-schizophrenia
#14
Cinzia Niolu, Emanuela Bianciardi, Michele Ribolsi, Alberto Siracusano
Schizophrenia is a debilitating illness, present in approximately 1% of the global population. It is manifested through positive symptoms including delusions, hallucinations, disorganized thoughts and negative symptoms such as avolition, alogia, and apathy. In 2013 the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) has been released and some changes were introduced to make diagnosis of schizophrenia more accurate and precise, but researchers are already studying how to improve again the diagnostic criteria of this disorder...
November 2016: Recenti Progressi in Medicina
https://www.readbyqxmd.com/read/27852968/-treatment-of-metacognitive-impairments-in-schizophrenia-the-metacognitive-training
#15
Zita Fekete, Edit Vass, Alexander Kancsev, Ildikó Kuritárné Szabó
In the recent years plenty of therapeutic treatment methods have been developed, aimed at neurocognitive impairments in schizophrenia. These trainingprograms can hold up promising results in the improvement of neurocognitive functions. Nevertheless the generalisation on the daily life is not perspicuous. A reason for it might be the supposition, that further factors such as metacognition and social cognition may play a mediator role between neurocognition and functional outcomes. As a result, many socialcognitive remediation methods and programs have emerged targeting the impairment of deficits both in the field of neuro- and social cognition and deficits of metacognition...
2016: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/27843197/a-correlative-classification-study-of-schizophrenic-patients-with-results-of-clinical-evaluation-and-structural-magnetic-resonance-images
#16
Wen-Lin Chu, Min-Wei Huang, Bo-Lin Jian, Chih-Yao Hsu, Kuo-Sheng Cheng
Patients with schizophrenia suffer from symptoms such as hallucination and delusion. There are currently a number of publications that discuss the treatment, diagnosis, prognosis, and damage in schizophrenia. This study utilized joint independent component analysis to process the images of GMV and WMV and incorporated the Wisconsin card sorting test (WCST) and the positive and negative syndrome scale (PANSS) to examine the correlation of obtained brain characteristics. We also used PANSS score to classify schizophrenic patients into acute and subacute cases, to analyze the brain structure differences...
2016: Behavioural Neurology
https://www.readbyqxmd.com/read/27815512/schizophrenia-impact-of-psychopathology-faith-healers-and-psycho-education-on-adherence-to-medications
#17
Karim Abdel Aziz, Mohammed H Elamin, Nisrin M El-Saadouni, Dina Aly El-Gabry, Mahmoud Barakat, Fatima Alhayyas, Hamdy F Moselhy
BACKGROUND: Many patients suffering from psychosis are nonadherent to their medications. Nonadherence can range from treatment refusal to irregular use or partial change in daily medication doses. AIM: To investigate whether symptom dimensions, post-discharge care plans and being involved with faith healer affect the adherence to treatment in patients with schizophrenia. METHOD: A total of 121 patients with schizophrenia were examined 6 weeks post-discharge from the inpatient unit and assessed for full, partial or nonadherence to medication...
December 2016: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/27793241/seizure-due-to-multiple-drugs-intoxication-a-case-report
#18
Handan Gulec, Munire Babayigit, Aysun Kurtay, Mehmet Sahap, Fatma Ulus, Zehra Tutal, Eyup Horasanli
The mechanism of the antidepressant effect of bupropion is not fully understood. Besides, using it in the treatment of depression, it is found to be effective in reducing withdrawal symptoms due to smoking cessation. A 28-year-old female patient with a history of depression was admitted to emergency department an hour after ingestion of bupropion, quetiapine, and levothyroxine in high doses to commit suicide. While accepting her into the Intensive Care Unit, she was awake, alert, disoriented and agitated. After 2h, the patient had a generalized tonic-clonic seizure...
November 2016: Brazilian Journal of Anesthesiology
https://www.readbyqxmd.com/read/27787708/neuropsychiatric-symptoms-of-cholinergic-deficiency-occur-with-degradation-of-the-projections-from-the-nucleus-basalis-of-meynert
#19
Jan Willem van Dalen, Matthan W A Caan, Willem A van Gool, Edo Richard
This study aims to evaluate the relation between a cluster of neuropsychiatric symptoms related to cholinergic deficiency and degradation of the cortical cholinergic projections which project from the nucleus basalis of Meynert to the cerebral cortex. An atlas of the pathway from the nucleus basalis to the cortex (NbM cortical pathway) was constructed using diffusion tensor imaging and tractography in 87 memory clinic patients. Structural degradation was considered to be represented by lower fractional anisotropy (FA) and higher mean diffusivity (MD)...
October 27, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27755991/risperidone-and-escitalopram-co-administration-a-potential-treatment-of-schizophrenia-symptoms-with-less-side-effects
#20
Katarzyna Kamińska, Karolina Noworyta-Sokołowska, Alexandra Jurczak, Anna Górska, Zofia Rogóż, Krystyna Gołembiowska
BACKGROUND: Schizophrenia is a psychiatric disorder characterized by positive and negative symptoms often accompanied by depression and cognitive deficits. Positive symptoms, like delusions and hallucinations are caused by an excess of dopamine (DA) signaling and are treated with the second generation antipsychotic drugs. Negative symptoms of schizophrenia are represented by social withdrawal, apathy and blunted emotional response. It was demonstrated that co-administration of risperidone and selective serotonin reuptake inhibitors alleviated depressive symptoms and cognitive dysfunction in animal models of schizophrenia...
February 2017: Pharmacological Reports: PR
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