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sweet's syndrome

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https://www.readbyqxmd.com/read/29121137/sweet-syndrome-induced-by-oral-acetaminophen-codeine-following-repair-of-a-facial-fracture
#1
Laurence M Bradley, Shauna P Higgins, Monee M Thomas, Ife J Rodney, Rebat M Halder
Sweet syndrome (SS), also known as acute febrile neutrophilic dermatosis, is an uncommon condition that is clinically characterized by painful, well-demarcated, indurated, erythematous plaques or nodules that typically favor the head, neck, and arms, and are accompanied by fever. The disease is divided into several categories based on the underlying etiology, with the drug-induced variant comprising a rising number of the total cases and being reported in association with an increasing number of medications...
September 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/29107342/sweet-syndrome-in-patients-with-and-without-malignancy-a-retrospective-analysis-of-83-patients-from-a-tertiary-academic-referral-center
#2
Caroline A Nelson, Megan H Noe, Christine M McMahon, Asha Gowda, Benedict Wu, Hovik J Ashchyan, Alexander E Perl, William D James, Robert G Micheletti, Misha Rosenbach
BACKGROUND: Sweet syndrome is a neutrophilic dermatosis that may be categorized into classic, malignancy-associated, and drug-induced subtypes. Few studies have systematically analyzed this rare disorder. OBJECTIVE: To describe the clinicopathologic characteristics and treatment of Sweet syndrome and identify characteristics associated with concurrent malignancy. METHODS: We retrospectively reviewed patients with Sweet syndrome at the University of Pennsylvania from 2005 to 2015...
October 26, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29106005/sweet-syndrom-revision-der-diagnostischen-kriterien
#3
REVIEW
Ahmad Nofal, Ayman Abdelmaksoud, Hala Amer, Eman Nofal, Ayman Yosef, Khaled Gharib, Waleed Albalat, Fatma Eldesouky, Howyda M Ebrahim, Ahmed Said Abdelshafy, Hala Fayed
No abstract text is available yet for this article.
November 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/29094232/phase-i-trial-of-bortezomib-daily-dose-safety-pharmacokinetic-profile-biological-effects-and-early-clinical-evaluation-in-patients-with-advanced-solid-tumors
#4
Rastislav Bahleda, Marie-Cécile Le Deley, Apexa Bernard, Shalini Chaturvedi, Michael Hanley, Audrey Poterie, Anas Gazzah, Andreea Varga, Mehdi Touat, Eric Deutsch, Christophe Massard, Helgi Van De Velde, Antoine Hollebecque, Magali Sallansonnet-Froment, Damien Ricard, Hervé Taillia, Eric Angevin, Vincent Ribrag, Jean-Charles Soria
Purpose This phase I study investigated bortezomib in solid tumors used as a daily subcutaneous regimen. Previous regimens showed only modest activity in solid tumors which was potentially related to sub-optimal tumor penetration. We aimed at exploring if daily low dose administration of bortezomib may allow a greater and tolerable pharmacokinetic exposure which might be required for antitumor activity in solid tumors. Patients and methods This 3 + 3 design, dose escalation, monocentric study aimed at defining the maximum tolerated dose of daily low dose schedule of bortezomib...
November 2, 2017: Investigational New Drugs
https://www.readbyqxmd.com/read/29078984/bullous-sweet-s-syndrome-with-myositis
#5
K Sato, T Miura, M Ohtsuka, T Yamamoto
No abstract text is available yet for this article.
October 24, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/29071870/-medication-rules-of-famous-veteran-traditional-chinese-medicine-doctor-in-treatment-of-chronic-bronchitis-based-on-implicit-structure-model
#6
Li-Ping Chen, Yong-Min Cai, Jian-Sheng Li
To explore the medication rules of famous veteran traditional Chinese medicine (TCM) doctors in treatment of chronic bronchitis, a structured medical record database for famous veteran TCM doctors in modern clinical books was established. First, Lantern 3.1.2(Kongmin light) implicit structure analysis software was used to build an implicit structure model and make an implicit interpretation. Then, SAS 9.1 was adopted to mine herb-herb, herb-symptom and herb-syndrome association rules. Through the mining, 1 274 commonly used herbs for chronic bronchitis were found, including liquorice, bitter almond, pinellia, dried tangerine or orange peel, poria cocos...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29054908/strange-case-of-dimorphic-skin-rash-in-a-patient-with-cirrhosis-atypical-herpes-simplex-and-sweet-s-syndrome
#7
Cyriac Abby Philips, Rajaguru Paramaguru, Philip Augustine
A middle-aged man with decompensated cirrhosis and a dimorphic multisite skin rash is diagnosed with rare atypical herpes simplex infection, manifesting Sweet's syndrome (SS) in the absence of other described associations. SS, an acute febrile neutrophilic dermatosis, has three common forms-classical or idiopathic, malignancy associated and drug induced. Systemic autoimmune, connective tissue diseases and infections are also strong associations. The latter is commonly described in Gram-positive bacteria, salmonellosis and Yersinia Herpes infections are a rare cause of SS, reported only thrice in literature, one with concomitant lupus, the second with associated mycobacterial infection and third, in metastatic breast disease in contrast to our patient...
October 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29044459/azacitidine-induced-sweet-syndrome-two-unusual-clinical-presentations
#8
Shevya M Tiwari, Tony Caccetta, Sujith P Kumarasinghe, Nathan Harvey
No abstract text is available yet for this article.
October 18, 2017: Australasian Journal of Dermatology
https://www.readbyqxmd.com/read/29016251/addressing-the-problem-of-obesity-and-associated-cardiometabolic-risk-in-black-south-african-women-time-for-action
#9
Julia H Goedecke
The PhD thesis of Gradidge, entitled 'Factors associated with obesity and metabolic syndrome in an ageing cohort of black women living in Soweto, Johannesburg (Study of Women in and Entering Endocrine Transition [SWEET])', attempts to understand the determinants of obesity and metabolic syndrome (MetS) in a population of urban-dwelling black South African women. A conceptual framework is presented, which positions obesity as the central risk factor for MetS, and includes the possible influence of socioeconomic status, lifestyle behaviours and body size perceptions, as key determinants of obesity...
2017: Global Health Action
https://www.readbyqxmd.com/read/28984691/intracorneal-pustular-drug-eruption-a-novel-cutaneous-adverse-event-in-anti-programmed-cell-death-1-patients-that-highlights-the-effect-of-anti-programmed-cell-death-1-in-neutrophils
#10
Cathy Yunjia Zhao, Germana Consuegra, Shaun Chou, Pablo Fernández-Peñas
The introduction of anti-programmed cell death-1 (anti-PD1) monoclonal antibodies has revolutionized the treatment of various advanced malignancies. Despite its efficacy, anti-PD1 therapy is accompanied by a variety of cutaneous adverse events. A 79-year-old man developed erythematous scaly plaques and pustules of the forehead, legs and arms after four cycles of nivolumab infusions every 2 weeks. Histology showed intracorneal pustules with dermal neutrophils and eosinophils. He was treated successfully with topical corticosteroids without discontinuation of nivolumab...
December 2017: Melanoma Research
https://www.readbyqxmd.com/read/28981179/sweet-s-syndrome-diagnostic-criteria-revisited
#11
REVIEW
Ahmad Nofal, Ayman Abdelmaksoud, Hala Amer, Eman Nofal, Ayman Yosef, Khaled Gharib, Waleed Albalat, Fatma Eldesouky, Howyda M Ebrahim, Ahmed Said Abdelshafy, Hala Fayed
The diagnosis of Sweet's syndrome (SS) is based on a set of criteria that requires the presence of two major and at least two minor criteria. In some cases, however, the diagnosis is not as straightforward due to the absence of certain criteria. The objective of the present study was to review the clinical, histopathological, and laboratory features of the current diagnostic criteria for SS, and to evaluate their validity in the cases reported in the literature as well as in 40 patients treated at our institution...
November 2017: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/28981149/an-interesting-case-of-pyoderma-gangrenosum-with-immature-hystiocytoid-neutrophils
#12
Catherine Besner Morin, Benoit Côté, Annie Belisle
We present a unique case of a 36-year-old male who developed more than twenty Pyoderma gangrenosum ulcers demonstrating on histopathology a dense inflammatory infiltrate composed of histiocytoid mononuclear immature cells with a strong positivity for myeloperoxidase and Leder stain, suggesting a myeloid lineage in the absence of a concomitant myeloproliferative disorder. Histiocytoid Sweet syndrome is now recognized as a histological subtype of Sweet syndrome. Although Pyoderma gangrenosum and Sweet syndrome belong to the spectrum of neutrophilic diseases, to the best of our knowledge, this is the first case of a "Histiocytoid Pyoderma gangrenosum" encompassing immature granulocytes in the absence of leukemia cutis...
October 5, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28978954/multiple-submucosal-masses-in-the-esophagus-esophageal-lymphangiomatosis
#13
Huiying Zhao, Weiran Xu, Zhihao Wang
No abstract text is available yet for this article.
October 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28971978/activation-of-the-sweet-taste-receptor-t1r3-by-the-artificial-sweetener-sucralose-regulates-the-pulmonary-endothelium
#14
Elizabeth O Harrington, Alexander Vang, Julie Braza, Aparna Shil, Havovi Chichger
A hallmark of acute respiratory distress syndrome (ARDS) is pulmonary vascular permeability. In these settings, loss of barrier integrity is mediated by cell-contact disassembly and actin-remodelling. Studies into molecular mechanisms responsible for improving microvascular barrier function are therefore vital in the development of therapeutic targets for reducing vascular permeability in ARDS. The sweet taste receptor, T1R3 is a GPCR, activated following exposure to sweet molecules, to trigger a gustducin-dependent signal cascade...
September 28, 2017: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/28966522/histiocytoid-sweet-syndrome-in-a-child-without-underlying-systemic-disease
#15
Seung Dohn Yeom, Hye Soo Ko, Jong Hyuk Moon, Min Ji Kang, Ji Won Byun, Gwang Seong Choi, Jeonghyun Shin
Sweet syndrome (acute, febrile, neutrophilic dermatosis) is characterized by the acute onset of an eruption of painful nodules or erythematous or violaceous plaques on the limbs, face and neck. These symptoms are accompanied by fever. The diagnostic features include histopathological findings of dermal neutrophilic infiltration without leukocytoclastic vasculitis or peripheral blood leukocytosis. Sweet syndrome is associated with infection, malignancies, autoimmune disease, pregnancy, and drugs. Patients with Sweet syndrome demonstrate a complete and rapid response to systemic steroid administration...
October 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28965534/a-minimally-processed-dietary-pattern-is-associated-with-lower-odds-of-metabolic-syndrome-among-lebanese-adults
#16
Lara Nasreddine, Hani Tamim, Leila Itani, Mona P Nasrallah, Hussain Isma'eel, Nancy F Nakhoul, Joana Abou-Rizk, Farah Naja
OBJECTIVE: To (i) estimate the consumption of minimally processed, processed and ultra-processed foods in a sample of Lebanese adults; (ii) explore patterns of intakes of these food groups; and (iii) investigate the association of the derived patterns with cardiometabolic risk. DESIGN: Cross-sectional survey. Data collection included dietary assessment using an FFQ and biochemical, anthropometric and blood pressure measurements. Food items were categorized into twenty-five groups based on the NOVA food classification...
October 2, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28958741/sweet-syndrome-caused-by-sensitization-to-gabapentin
#17
Patricia Rojas-Pérez-Ezquerra, Blanca Noguerado-Mellado, Mercedes Sáenz de Santamaría García, Dasha Roa-Medellín, Ignacio Hernández-Aragüés, José Manuel Zubeldia Ortuño
No abstract text is available yet for this article.
September 22, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28957773/a-rare-case-report-describing-the-relation-between-sweet-syndrome-and-spontaneous-recurrent-peritonitis
#18
Y Rajjoub, N Saffaf, A Goodman
INTRODUCTION: Sweet syndrome (acute febrile neutrophilic dermatosis) is a subset of rare inflammatory disorders, first described by Dr. Robert Douglas Sweet in 1964 (Sweet, 1964). The co-existence of Sweet syndrome and spontaneous recurrent peritonitis has never been previously mentioned in the medical literature. PRESENTATION OF CASE: We report a case of a 37-year old female patient with known idiopathic Sweet syndrome, diagnosed on skin biopsy, who presented with multiple episodes of spontaneous peritonitis...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28951713/sweet-s-syndrome-with-idiopathic-epididymitis
#19
Urszula Adamska, Kaja Męcińska-Jundziłł, Agnieszka Białecka, Adam Cichewicz, Aleksandra Grzanka, Piotr Adamski, Dzmitry Khvoryk, Rafał Czajkowski
No abstract text is available yet for this article.
August 2017: Postȩpy Dermatologii i Alergologii
https://www.readbyqxmd.com/read/28941785/neutrophilic-dermatosis-of-the-hands-a-review-of-17-cases
#20
Anthony M Y Cheng, Harriet S Cheng, Belinda J Smith, David A Stewart
PURPOSE: Neutrophilic dermatosis of the hands is an inflammatory skin condition related to Sweet syndrome that responds to corticosteroids. It commonly affects the dorsum of the hand and often mimics infection, with violaceous inflammatory papules and plaques that may ulcerate. The aim of this study was to review the clinical presentation of neutrophilic dermatosis of the hands. METHODS: A retrospective review was undertaken of all cases of neutrophilic dermatosis of the hands seen at a tertiary hospital in New South Wales, Australia, over a 5-year period...
September 21, 2017: Journal of Hand Surgery
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