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https://www.readbyqxmd.com/read/28527459/osmotic-and-diffusio-osmotic-flow-generation-at-high-solute-concentration-i-mechanical-approaches
#1
Sophie Marbach, Hiroaki Yoshida, Lydéric Bocquet
In this paper, we explore various forms of osmotic transport in the regime of high solute concentration. We consider both the osmosis across membranes and diffusio-osmosis at solid interfaces, driven by solute concentration gradients. We follow a mechanical point of view of osmotic transport, which allows us to gain much insight into the local mechanical balance underlying osmosis. We demonstrate in particular how the general expression of the osmotic pressure for mixtures, as obtained classically from the thermodynamic framework, emerges from the mechanical balance controlling non-equilibrium transport under solute gradients...
May 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28520883/effect-of-isotonic-versus-hypotonic-maintenance-fluid-therapy-on-urine-output-fluid-balance-and-electrolyte-homeostasis-a-crossover-study-in-fasting-adult-volunteers
#2
N Van Regenmortel, T De Weerdt, A H Van Craenenbroeck, E Roelant, W Verbrugghe, K Dams, M L N G Malbrain, T Van den Wyngaert, P G Jorens
Background.: Daily and globally, millions of adult hospitalized patients are exposed to maintenance i.v. fluid solutions supported by limited scientific evidence. In particular, it remains unclear whether fluid tonicity contributes to the recently established detrimental effects of fluid, sodium, and chloride overload. Methods.: This crossover study consisted of two 48 h study periods, during which 12 fasting healthy adults were treated with a frequently prescribed solution (NaCl 0...
May 16, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28511791/-usefulness-of-the-budget-and-the-balanced-scorecard-in-managing-primary-care-centres-impact-on-staff-motivation
#3
Juan Manuel Ramón-Jerónimo, Raquel Flórez-López, Natalia Domínguez-Lario
OBJECTIVE: To analyse the utility perceived by managers of centers of primary care about management tools (budget and balanced scorecard), together their impact on human resources motivation. DESIGN: Qualitative study (case study) based on grounded theory performed between January and June 2014. LOCATION: Units of Clinical Management of Primary Health (UGCAP) in Metropolitan Health Area of Seville, Spain. PARTICIPANTS: UGCAP managers and Health Area (CEO) managers...
May 13, 2017: Atencion Primaria
https://www.readbyqxmd.com/read/28510497/clinical-development-and-commercialization-of-advanced-therapy-medicinal-products-atmps-in-the-eu-how-are-the-product-pipeline-and-regulatory-framework-evolving
#4
Tomáš Boráň, Margarida Menezes-Ferreira, Ilona Reischl, Patrick Celis, Nicolas Ferry, Bernd Gänsbacher, Hartmut Krafft, Michele Lipucci Di Paola, Dariusz Sladowski, Paula Salmikangas
The research and development of Advanced Therapy Medicinal Products (ATMPs) has been active in Europe and worldwide during recent years, yet the number of licensed products remains still low. The main expected legal change in near future in the EU concerns the regulation on clinical trials (536/2014), which will come into force in 2018. With this new framework a more harmonized and swift process for approval of clinical trials is awaited, which is expected to support the entry of new innovations into the EU market...
May 16, 2017: Human Gene Therapy. Clinical Development
https://www.readbyqxmd.com/read/28508431/a-spatially-balanced-design-with-probability-function-proportional-to-the-within-sample-distance
#5
Roberto Benedetti, Federica Piersimoni
The units observed in a biological, agricultural, and environmental survey are often randomly selected from a finite population whose main feature is to be geo-referenced thus its spatial distribution should be used as essential information in designing the sample. In particular our interest is focused on probability samples that are well spread over the population in every dimension which in recent literature are defined as spatially balanced samples. To approach the problem we used the within sample distance as the summary index of the spatial distribution of a random selection criterion...
May 16, 2017: Biometrical Journal. Biometrische Zeitschrift
https://www.readbyqxmd.com/read/28504573/human-norovirus-and-its-surrogates-induce-plant-immune-response-in-arabidopsis-thaliana-and-lactuca-sativa
#6
Sarah M Markland, Harsh Bais, Kalmia E Kniel
Human norovirus is the leading cause of foodborne illness worldwide with the majority of outbreaks linked to fresh produce and leafy greens. It is essential that we thoroughly understand the type of relationship and interactions that take place between plants and human norovirus to better utilize control strategies to reduce transmission of norovirus in the field onto plants harvested for human consumption. In this study the expression of gene markers for the salicylic acid (SA) and jasmonic acid (JA) plant defense pathways was measured and compared in romaine lettuce (Lactuca sativa) and Arabidopsis thaliana Col-0 plants that were inoculated with Murine Norovirus-1, Tulane Virus, human norovirus GII...
May 15, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/28499823/structural-and-mechanistic-insights-into-mycothiol-disulphide-reductase-and-the-mycoredoxin-1-alkylhydroperoxide-reductase-e-assembly-of-mycobacterium-tuberculosis
#7
Arvind Kumar, Wilson Nartey, Joon Shin, Malathy Sony Subramanian Manimekalai, Gerhard Grüber
Mycobacteria employ a versatile machinery of the mycothiol-dependent system, containing the proteins mycothiol disulfide reductase (Mtr), the oxido-reductase Mycoredoxin-1 (Mrx-1) and the alkyl-hydroperoxide subunit E (AhpE). The mycothiol-dependent protein ensemble regulates the balance of oxidized-reduced mycothiol, to ensure a reductive intracellular environment for optimal functioning of its proteins even upon exposure to oxidative stress. Here, we determined the first low-resolution solution structure of Mycobacterium tuberculosis Mtr (MtMtr) derived from small-angle X-ray scattering data, which provides insight into its dimeric state...
May 9, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/28499798/pilot-trial-on-separation-conditions-for-diaper-recycling
#8
Kyung-Shin Kim, Hee-Sun Cho
By utilizing laboratory-scale tests, the optimal separation conditions for diaper recycling were identified, and then, these conditions were validated by a pilot trial. In this research, we determined the mass balances derived during various processing steps and identified the most feasible procedures to use for separating each material in the output flow. The results showed that drum screening was not able to remove all the fiber and super absorbent particles (SAP) in the plastic-rich fraction and that cellulose enzyme treatment can be a good solution...
May 9, 2017: Waste Management
https://www.readbyqxmd.com/read/28499576/an-introduction-to-the-model-of-crisis-intervention-procedure-for-borderline-patients-cip-bp-a-case-study
#9
Tytus Koweszko, Jacek Gierus, Magdalena Więdłocha, Anna Mosiołek, Agata Szulc
Borderline personality disorder is highly associated with suicidal behaviors. The authors of the current case study present the introduction model of original Crisis Intervention Procedure for Borderline Patients (CIP-BP) which is a method focused on restoring emotional balance, reducing the severity of symptoms and the risk of suicidal behavior, as well as developing optimum solutions for further action. Its aim is to enable the patient to regain control of their emotional memory, increase autonomy and restore important interpersonal relations by using the original resources of this person...
June 2017: Archives of Psychiatric Nursing
https://www.readbyqxmd.com/read/28497841/effect-of-fluid-resuscitation-with-balanced-solutions-on-platelets-in-vitro-simulation-of-20-volume-substitution
#10
Łukasz J Krzych, Piotr F Czempik
BACKGROUND: Fluid resuscitation in massive bleeding may cause coagulation disorders by dilution of platelets and clotting factors or by the definite influence on theirfunction. The aim of this study was to investigate the effects of balanced crystalloid and colloid solutions on platelets (PLT) in vitro using complex assessment of coagulation. METHODS: The study group was comprised of 32 American Society of Anesthesiologists physical status class I male volunteers, aged 21-35 (29 ± 4) years, weighting 59-103 (81...
May 12, 2017: Cardiology Journal
https://www.readbyqxmd.com/read/28497476/optimization-of-a-novel-large-field-of-view-distortion-phantom-for-mr-only-treatment-planning
#11
Ryan G Price, Robert A Knight, Ken-Pin Hwang, Ersin Bayram, Siamak P Nejad-Davarani, Carri K Glide-Hurst
PURPOSE: MR-only treatment planning requires images of high geometric fidelity, particularly for large fields of view (FOV). However, the availability of large FOV distortion phantoms with analysis software is currently limited. This work sought to optimize a modular distortion phantom to accommodate multiple bore configurations and implement distortion characterization in a widely implementable solution. METHOD AND MATERIALS: To determine candidate materials, 1...
May 12, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28494212/retinal-toxicity-of-acai-fruit-euterpe-oleracea-dye-concentrations-in-rabbits-basic-principles-of-a-new-dye-for-chromovitrectomy-in-humans
#12
Rafael R Caiado, Cristiane S Peris, Acácio Alves Souza Lima-Filho, Joao Guilherme Palma Urushima, Eduardo Novais, Emmerson Badaró, André Maia, Rita Sinigaglia-Coimbra, Sung Eun S Watanabe, Eduardo B Rodrigues, Michel Eid Farah, Mauricio Maia
PURPOSE: Evaluate toxicity of acai fruit (Euterpe oleracea) dye concentrations in a rabbit model. METHODS: Rabbits were injected intravitreously with 10%, 25%, and 35% acai dye concentrations. Control eyes received balanced salt solution (BSS). Electroretinogram (ERG), fundus imaging, fluorescein angiography (FA), optical coherence tomography (OCT), and light and transmission electron microscopy (LM/TEM) were performed. RESULTS: Fundus imaging showed increased vitreous opacity with increased dye concentrations...
May 11, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28493289/intestinal-epithelial-claudins-expression-and-regulation-in-homeostasis-and-inflammation
#13
REVIEW
Vicky Garcia-Hernandez, Miguel Quiros, Asma Nusrat
The intestinal epithelium forms a highly dynamic and selective barrier that controls absorption of fluid and solutes while restricting pathogen access to underlying tissues. Barrier properties are achieved by intercellular junctions that include an apical tight junction (TJ) and subjacent adherens junctions and desmosomes. The TJ tetraspan claudin proteins form pores between epithelial cells to control paracellular fluid and ion movement. In addition to regulation of barrier function, claudin family members control epithelial homeostasis and are expressed in a spatiotemporal manner in the intestinal crypt-luminal axis...
May 10, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28493192/simulating-water-and-nitrogen-loss-from-an-irrigated-paddy-field-under-continuously-flooded-condition-with-hydrus-1d-model
#14
Rui Yang, Juxiu Tong, Bill X Hu, Jiayun Li, Wenshuo Wei
Agricultural non-point source pollution is a major factor in surface water and groundwater pollution, especially for nitrogen (N) pollution. In this paper, an experiment was conducted in a direct-seeded paddy field under traditional continuously flooded irrigation (CFI). The water movement and N transport and transformation were simulated via the Hydrus-1D model, and the model was calibrated using field measurements. The model had a total water balance error of 0.236 cm and a relative error (error/input total water) of 0...
May 11, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28492520/an-ecologically-controlled-exoskeleton-can-improve-balance-recovery-after-slippage
#15
V Monaco, P Tropea, F Aprigliano, D Martelli, A Parri, M Cortese, R Molino-Lova, N Vitiello, S Micera
The evolution to bipedalism forced humans to develop suitable strategies for dynamically controlling their balance, ensuring stability, and preventing falling. The natural aging process and traumatic events such as lower-limb loss can alter the human ability to control stability significantly increasing the risk of fall and reducing the overall autonomy. Accordingly, there is an urgent need, from both end-users and society, for novel solutions that can counteract the lack of balance, thus preventing falls among older and fragile citizens...
May 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28491466/changes-in-retinal-function-and-cellular-remodeling-following-experimental-retinal-detachment-in-a-rabbit-model
#16
Tilda Barliya, Ron Ofri, Shai Sandalon, Dov Weinberger, Tami Livnat
Purpose. To explore functional electroretinographic (ERG) changes and associated cellular remodeling following experimental retinal detachment in a rabbit model. Methods. Retinal detachment was created in ten rabbits by injecting 0.1 ml balanced salt solution under the retina. Fundus imaging was performed 0, 3, 7, 14, and 21 days postoperatively. ERGs were recorded pre- and 7 and 21 days postoperatively. Eyes were harvested on day 21 and evaluated immunohistochemically (IHC) for remodeling of second- and third-order neurons...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/28489182/acute-effects-of-intradialytic-aerobic-exercise-on-solute-removal-blood-gases-and-oxidative-stress-in-patients-with-chronic-kidney-disease
#17
Joseane Böhm, Mariane Borba Monteiro, Francini Porcher Andrade, Francisco Veronese, Fernando Saldanha Thomé
Introduction: Hemodialysis contributes to increased oxidative stress and induces transitory hypoxemia. Compartmentalization decreases the supply of solutes to the dialyzer during treatment. The aim of this study was to investigate the acute effects of intradialytic aerobic exercise on solute removal, blood gases and oxidative stress in patients with chronic kidney disease during a single hemodialysis session. Methods: Thirty patients were randomized to perform aerobic exercise with cycle ergometer for lower limbs during 30 minutes with intensity between 60-70% of maximal heart rate, or control group (CG)...
April 27, 2017: Jornal Brasileiro de Nefrologia: ʹorgão Oficial de Sociedades Brasileira e Latino-Americana de Nefrologia
https://www.readbyqxmd.com/read/28489067/a-study-protocol-for-applying-user-participation-and-co-learning-lessons-learned-from-the-ebalance-project
#18
Anna Cristina Åberg, Kjartan Halvorsen, Ingrid From, Åsa Bergman Bruhn, Lars Oestreicher, Anita Melander-Wikman
The eBalance project is based on the idea that serious exergames-i.e., computer gaming systems with an interface that requires physical exertion to play-that are well adapted to users, can become a substantial part of a solution to recognized problems of insufficient engagement in fall-prevention exercise and the high levels of fall-related injuries among older people. This project is carried out as a collaboration between eight older people who have an interest in balance training and met the inclusion criteria of independence in personal activities of daily living, access to and basic knowledge of a computer, four staff working with the rehabilitation of older adults, and an interdisciplinary group of six research coordinators covering the areas of geriatric care and rehabilitation, as well as information technology and computer science...
May 10, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28489054/a-survey-on-an-energy-efficient-and-energy-balanced-routing-protocol-for-wireless-sensor-networks
#19
Olayinka O Ogundile, Attahiru S Alfa
Wireless sensor networks (WSNs) form an important part of industrial application. There has been growing interest in the potential use of WSNs in applications such as environment monitoring, disaster management, health care monitoring, intelligence surveillance and defence reconnaissance. In these applications, the sensor nodes (SNs) are envisaged to be deployed in sizeable numbers in an outlying area, and it is quite difficult to replace these SNs after complete deployment in many scenarios. Therefore, as SNs are predominantly battery powered devices, the energy consumption of the nodes must be properly managed in order to prolong the network lifetime and functionality to a rational time...
May 10, 2017: Sensors
https://www.readbyqxmd.com/read/28487646/human-inspired-eigenmovement-concept-provides-coupling-free-sensorimotor-control-in-humanoid-robot
#20
Alexei V Alexandrov, Vittorio Lippi, Thomas Mergner, Alexander A Frolov, Georg Hettich, Dusan Husek
Control of a multi-body system in both robots and humans may face the problem of destabilizing dynamic coupling effects arising between linked body segments. The state of the art solutions in robotics are full state feedback controllers. For human hip-ankle coordination, a more parsimonious and theoretically stable alternative to the robotics solution has been suggested in terms of the Eigenmovement (EM) control. Eigenmovements are kinematic synergies designed to describe the multi DoF system, and its control, with a set of independent, and hence coupling-free, scalar equations...
2017: Frontiers in Neurorobotics
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