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Pulmonary stenosis

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https://www.readbyqxmd.com/read/29660902/effect-of-rho-kinase-inhibitor-fasudil-on-the-expression-et-1-and-no-in-rats-with-hypoxic-pulmonary-hypertension
#1
Xing-Zhen Sun, Shu-Yan Li, Xiang-Yang Tian, Ze Hong, Jia-Xin Li
OBJECTIVE: This study aims to study the effect of Rho kinase inhibitor fasudil on the expression endothelin-1 (ET-1) and nitric oxide (NO) in rats with hypoxic pulmonary hypertension (HPH). METHODS: Twenty-four male SD rats were randomly divided into three groups: control group, model group (HPH group) and HPH+fasudil group. The rat HPH model was established by intermittent hypoxia (IH) at atmospheric pressure. Mean pulmonary artery pressure (mPAP), right ventricular hypertrophy index (RVHI), ET-1 and NO levels, and pulmonary vascular structural changes were observed in all groups...
April 12, 2018: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/29657239/application-of-a-fresh-decellularized-pulmonary-allograft-for-pulmonary-valve-replacement-in-japan
#2
Hideto Ozawa, Takayoshi Ueno, Masaki Taira, Koichi Toda, Toru Kuratani, Yoshiki Sawa
BACKGROUND: Tissue engineering has advanced the technique of decellularization of the heart valve. The valve is reseeded with the patient's own cells after implantation with suppression of immunologic reactions. The same advantage has been reported for fresh decellularized heart valves, and more than 10 years of excellent outcomes have been achieved. We began performing such heart valve implantations in 2013 as part of a clinical study at Osaka University. We report our evaluation of the safety and efficacy of heart valve implantation...
April 14, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29657080/right-ventricular-energetics-and-power-in-pulmonary-regurgitation-vs-stenosis-using-four-dimensional-phase-contrast-magnetic-resonance
#3
Joao Filipe Fernandes, James M Hammel, Jia Zhou, Yunbin Xiao, Manuela Chen, Rita Alves, John Lof, Stuart M Grieve, Andreas Schuster, Titus Kuehne, Shelby Kutty
OBJECTIVE: We investigated a full energetic profile of pressure and volume loaded right ventricle (RV) in porcine models by evaluating kinetic energy (KE), stroke power, power output and power loss across pulmonary valves with stenosis (PS) or with regurgitation (PR). METHODS: Fifteen pigs (6 PS and 6 PR, 3 unoperated controls) were studied. Phase-contrast 4D-flow MRI was performed in models of PS and PR at baseline and at 10-12 weeks, in conjunction with cardiac catheterization...
April 4, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29655764/anomalous-pulmonary-venous-drainage-and-pulmonary-vein-stenosis
#4
Laura Díaz-Chirón, Helena Cigarrán, Jacobo Silva
No abstract text is available yet for this article.
April 11, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29652681/direct-ultrasound-of-the-pulmonary-artery-helps-diagnose-a-rare-cause-of-right-ventricular-failure-after-heart-transplantation-a-case-report
#5
John S McNeil, Si M Pham, Julie L Huffmyer
Pulmonary artery anastomosis stenosis is a rare cause of right ventricular failure after orthotopic heart transplantation. In this case report, direct ultrasound of the pulmonary artery helped diagnose stenosis at a location not visible on transesophageal echocardiography or even with standard epicardial ultrasound views. It is important to evaluate all vascular anastomoses after heart or lung transplantation because surgical revision of these lesions is facile, but if left undiagnosed, significant morbidity or mortality is likely...
April 15, 2018: A&A practice
https://www.readbyqxmd.com/read/29652272/comparison-of-immediate-extubation-versus-ultrafast-tracking-strategy-in-the-management-of-off-pump-coronary-artery-bypass-surgery
#6
Amarja Sachin Nagre, Nagesh P Jambures
Introduction: Ultrafast tracking of anesthesia (UFTA) is practiced routinely, whereas immediate on-table extubation after off-pump coronary artery bypass (OPCAB) grafting surgery has many concerns. The purpose of our study was to evaluate the safety and feasibility of immediate extubation (IE) versus UFTA. Methods: Sixty patients were enrolled who underwent OPCAB surgery. The two groups IE and UFTA had thirty patients each. Inclusion criteria were patients for OPCAB surgery including left main stenosis...
April 2018: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/29650544/evaluation-and-management-of-right-sided-heart-failure-a-scientific-statement-from-the-american-heart-association
#7
REVIEW
Marvin A Konstam, Michael S Kiernan, Daniel Bernstein, Biykem Bozkurt, Miriam Jacob, Navin K Kapur, Robb D Kociol, Eldrin F Lewis, Mandeep R Mehra, Francis D Pagani, Amish N Raval, Carey Ward
BACKGROUND AND PURPOSE: The diverse causes of right-sided heart failure (RHF) include, among others, primary cardiomyopathies with right ventricular (RV) involvement, RV ischemia and infarction, volume loading caused by cardiac lesions associated with congenital heart disease and valvular pathologies, and pressure loading resulting from pulmonic stenosis or pulmonary hypertension from a variety of causes, including left-sided heart disease. Progressive RV dysfunction in these disease states is associated with increased morbidity and mortality...
April 12, 2018: Circulation
https://www.readbyqxmd.com/read/29650415/pulmonary-vein-stenosis-in-infants-a-systematic-review-meta-analysis-and-meta-regression
#8
Carl H Backes, Erin Nealon, Aimee K Armstrong, Clifford L Cua, Courtney Mitchell, Usha Krishnan, Rachel D Vanderlaan, Mi Kyoung Song, Nicola Viola, Charles V Smith, Patrick I McConnell, Brian K Rivera, Jeffrey Bridge
OBJECTIVE: To quantify outcomes of infants (<1 year of age) diagnosed with pulmonary vein stenosis (PVS). STUDY DESIGN: MEDLINE (PubMed), Scopus, and Web of Science were searched through February 1, 2017, with no language restrictions. Publications including infants diagnosed with primary PVS, defined as the absence of preceding intervention(s), were considered. The study was performed according to Meta-analysis of Observational Studies in Epidemiology guidelines, the Systematic Reviews, and Meta-Analysis checklist, and registered prospectively...
April 9, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29648693/anomalous-systemic-and-pulmonary-veins-an-unusual-coexistence
#9
Priyadarshini Arunakumar, Anoop Ayyappan, Deepa Sasikumar, K M Krishnamoorthy
A 12-year-old child presented with recurrent respiratory infections and was diagnosed with Scimitar syndrome. Drainage of IVC and course of aberrant arterial supply from aorta were not clear by echocardiogram, and hence, additional imaging was planned. CT unraveled the presence of a rare combination of anomalous pulmonary venous connection (APVC) to IVC, with near-atresia/severe stenosis of IVC, superior to the drainage of scimitar vein. There was a prominent azygos vein with preferential contrast opacification on lower limb injection...
April 12, 2018: Echocardiography
https://www.readbyqxmd.com/read/29643129/vessel-stretching-is-a-cause-of-lumen-enlargement-immediately-after-balloon-pulmonary-angioplasty-intravascular-ultrasound-analysis-in-patients-with-chronic-thromboembolic-pulmonary-hypertension
#10
Hiroto Shimokawahara, Aiko Ogawa, Hiroki Mizoguchi, Hiroki Yagi, Hidekazu Ikemiyagi, Hiromi Matsubara
BACKGROUND: Balloon pulmonary angioplasty (BPA) has become an alternative therapy for patients with chronic thromboembolic pulmonary hypertension who are ineligible for pulmonary endarterectomy. We retrospectively investigated intravascular ultrasound measurements to elucidate how the lumen enlarges immediately after BPA. METHODS AND RESULTS: A total of 326 lesions in 71 patients with chronic thromboembolic pulmonary hypertension were analyzed. The cross-sectional areas (CSAs) of the external elastic membrane and lumen measured by intravascular ultrasound before and after BPA were assessed for each lesion type (type A, ring-like stenosis lesions; type B, web lesions; type C, subtotal occlusion lesions)...
April 2018: Circulation. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29629260/acute-right-ventricular-failure-postintubation-in-a-mitral-stenosis-patient
#11
Sridhar Reddy Musuku, Saroj Pani, John Cagino
Mitral stenosis (MS) is prevalent in 0.02-0.2% of the population in developed countries. The pathophysiology of MS results in elevated left atrial pressures and over-time results in pulmonary hypertension (HTN) which ultimately affects the right ventricle. In addition, MS restricts the diastolic filling of the left ventricle. Therefore, during induction patients with MS are limited by their ability to increase cardiac output by increasing stroke volume. Anesthesia goals in severe MS are to avoid sudden changes in heart rate, as well as systemic and pulmonary artery pressures...
January 2018: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/29628594/an-unusual-case-of-a-parturient-with-uncorrected-pentalogy-of-fallot-presenting-for-elective-cesarean-section-delivery-of-twins
#12
Ying Ci Ho, Sek Koon Boey, Abey Matthew Varughese Mathews, Hooi Geok See, Nian Chih Hwang
We present a 31-year-old primigravida with uncorrected pentalogy of Fallot, pregnant with monochorionic-diamniotic twins, undergoing elective lower segment cesarean section at 36 weeks gestation. Preoperative workup included a transthoracic echocardiogram which revealed a large ventricular septal defect of 1.8 cm with bidirectional shunting, a moderate size atrial septal defect of 1.8 cm with predominant left-to-right shunting, an overriding aorta, moderate right ventricular hypertrophy, and severe pulmonary valve stenosis...
January 2018: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/29625509/adult-congenital-heart-disease-with-pregnancy
#13
REVIEW
Koichiro Niwa
The number of women with congenital heart disease (CHD) at risk of pregnancy is growing because over 90% of them are grown-up into adulthood. The outcome of pregnancy and delivery is favorable in most of them provided that functional class and systemic ventricular function are good. Women with CHD such as pulmonary hypertension (Eisenmenger syndrome), severe left ventricular outflow stenosis, cyanotic CHD, aortopathy, Fontan procedure and systemic right ventricle (complete transposition of the great arteries [TGA] after atrial switch, congenitally corrected TGA) carry a high-risk...
April 2018: Korean Circulation Journal
https://www.readbyqxmd.com/read/29623556/anesthesia-for-interventional-pulmonology-procedures-a-review-of-advanced-diagnostic-and-therapeutic-bronchoscopy
#14
Andres de Lima, Fayez Kheir, Adnan Majid, John Pawlowski
PURPOSE: Interventional pulmonology is a growing subspecialty of pulmonary medicine with flexible and rigid bronchoscopies increasingly used by interventional pulmonologists for advanced diagnostic and therapeutic purposes. This review discusses different technical aspects of anesthesia for interventional pulmonary procedures with an emphasis placed on pharmacologic combinations, airway management, ventilation techniques, and common complications. SOURCE: Relevant medical literature was identified by searching the PubMed and Google Scholar databases for publications on different anesthesia topics applicable to interventional pulmonary procedures...
April 5, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29618679/low-risk-of-pulmonary-vein-stenosis-after-contemporary-atrial-fibrillation-ablation-lessons-from-repeat-procedures-after-radiofrequency-current-cryoballoon-and-laser-balloon
#15
Takahiko Nagase, Stefano Bordignon, Laura Perrotta, Fabrizio Bologna, Felix K Weise, Athanasios Konstantinou, Ritsushi Kato, Boris Schmidt, Julian K R Chun
BACKGROUND: The incidence of pulmonary vein stenosis (PVS) after AF ablation following contemporary procedures remains unclear. We compared the incidence of PVS/narrowing (PVS/N) after PV isolation (PVI) for (1) 3-D mapping-guided wide-area encircling irrigated radiofrequency current (RFC) ablation; (2) first-third-generation big cryoballoon (CB1-3) ablation; and (3) laser balloon (LB) ablation.Methods and Results:All patients undergoing a second procedure between January 2012 and November 2016 were subgrouped according to index ablation (PVI): RFC; CB; or LB...
April 5, 2018: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29617762/pressure-gradient-vs-flow-relationships-to-characterize-the-physiology-of-a-severely-stenotic-aortic-valve-before-and-after-transcatheter-valve-implantation
#16
Nils P Johnson, Jo M Zelis, Pim A L Tonino, Patrick Houthuizen, R Arthur Bouwman, Guus R G Brueren, Daniel T Johnson, Jacques J Koolen, Hendrikus H M Korsten, Inge F Wijnbergen, Frederik M Zimmermann, Richard L Kirkeeide, Nico H J Pijls, K Lance Gould
Aims: Echocardiography and tomographic imaging have documented dynamic changes in aortic stenosis (AS) geometry and severity during both the cardiac cycle and stress-induced increases in cardiac output. However, corresponding pressure gradient vs. flow relationships have not been described. Methods and results: We recruited 16 routine transcatheter aortic valve implantations (TAVI's) for graded dobutamine infusions both before and after implantation; 0.014″ pressure wires in the aorta and left ventricle (LV) continuously measured the transvalvular pressure gradient (ΔP) while a pulmonary artery catheter regularly assessed cardiac output by thermodilution...
April 2, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29615091/rheumatic-heart-disease-in-the-south-west-region-of-cameroon-a-hospital-based-echocardiographic-study
#17
Clovis Nkoke, Anastase Dzudie, Christelle Makoge, Engelbert Bain Luchuo, Ahmadou Musa Jingi, Samuel Kingue
OBJECTIVE: Rheumatic heart disease (RHD) prevails as a major public health problem in sub-Saharan Africa. In Cameroon, reports on RHD have been so far limited to a few cities. We sought to describe the demographic, clinical and echocardiographic features of rheumatic heart disease in the Buea Regional Hospital, South West region of Cameroon. Echocardiography reports between June 2016 and June 2017 were reviewed. The diagnosis of RHD was based on the World Heart Federation Criteria for the diagnosis of RHD...
April 3, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29611831/anesthetic-management-for-concomitant-correction-of-congenital-cardiac-defects-and-long-o-ring-tracheal-stenosis-a-role-for-heliox-report-of-2-cases
#18
Sylvain Mauron, David Longchamp, Marie-Hélène Perez, René Prêtre, Kishore Sandu, Stefano Di Bernardo, Yann Boegli, Mirko Dolci
We present 2 infants with the rare association of long congenital tracheal stenosis, ventricular septal defect, and pulmonary hypertension. We describe a step-by-step assessment of the patients and the necessary procedures for a successful concomitant repair of both cardiac and tracheal malformations. The use of a helium-oxygen mixture (heliox) for the induction of anesthesia and pre-cardiopulmonary bypass is discussed.
March 15, 2018: A&A practice
https://www.readbyqxmd.com/read/29609227/-characteristics-and-prognosis-of-interrupted-inferior-vena-cava-with-azygous-continuation
#19
Q Xu, H X Sun, J S Xie, J L Wang, Q Y Pei, X H Zhang
Objective: To explore the clinical characteristics of interrupted of the inferior vena cava with azygous continuation and the prognosis. Methods: Retrospective analysis of 21 fetuses diagnosed with interrupted inferior vena cava with azygous continuation among 28 567 pregnant women who underwent routine ultrasound scan. The clinical data, ultrasonographic features, genetic information and prognosis were collected. Results: Interrupted of the inferior vena cava with azygous continuation occurred in 21(0.07%, 21/28 567) of 28 567 patients...
March 25, 2018: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/29607478/a-rare-case-of-rheumatic-heart-disease-with-stenosis-and-incompetence-of-three-valves-in-a-nigerian-woman
#20
B N Okeahialam
BACKGROUND: Though valve disease resulting from rheumatic heart disease is common, triple valve involvement is uncommon; with a bleak survival outlook Objective: To report a 38-year-old patient with both stenosis and incompetence of 3 valves, who lived till adulthood and went into heart failure after child-birth. No such report has come from Nigeria Methods: Case report of a Nigerian woman who lived with multiple valve disease up to adulthood when after delivery she developed hypertension and went into heart failure...
January 2018: West African Journal of Medicine
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