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Décio Medeiros Peixoto, José Angelo Rizzo, Deborah Schor, Almerinda Rêgo Silva, Dinaldo Cavalcanti de Oliveira, Dirceu Solé, Emanuel Sarinho
OBJECTIVE: To evaluate the immediate improvement rate of irritative cough in patients treated with the combination of Ananas comosus extract and honey (Bromelin(®)) compared with the use of honey alone (placebo group). METHODS: Pragmatic, double-blind, randomized, parallel-group study with children aged between 2 and 15 years, with irritative cough for at least 24hours. The double-blind assessment of cough was through the number of observed coughing episodes and intensity score for a period of 10minutes of observation...
April 16, 2016: Revista Paulista de Pediatria: Orgão Oficial da Sociedade de Pediatria de São Paulo
Raffaele Marzano, Nicola Dinelli, Valeria Ales, Maria Antonella Bertozzi
Prostatic inflammation is widespread in the male population. Two groups of 50 patients each with symptoms of prostatic inflammation and ecocolorDoppler indicative of prostatitis were identified. Both groups were further subdivided into two subgroups (respectively A1, A2, B1, and B2). Group A1 underwent therapy with oral levofloxacin 500 mg daily for 10 days plus co-treatment with oral Serenoa repens (320 mg) plus Bromeline plus Nettle (Prostamev Plus®) daily for two months; Group A2 with oral levofloxacin 500 mg daily for 10 days plus oral Serenoa repens extract 320 mg/day for two months; Group B1 specific antibiotic treatment for 10 days (included levofloxacin if sensitive) plus co-treatment with oral Serenoa repens (320 mg) plus Bromeline plus Nettle (Prostamev Plus®) daily for two months; Group B2 with specific antibiotic treatment for 10 days plus Serenoa repens 320 mg/day for two months...
March 2015: Archivio Italiano di Urologia, Andrologia
M Molteni
AIM: Given the limited efficacy of conventional medical therapy for functional dyspepsia, patients frequently seek alternative medical approaches. The use of suc h alternative therapies has dramatically increased during the last decades. The scope of this prospective study was to provide evidence of the clinical benefit of the treatment of functional dyspepsia with a dietary integrator composed by sodium alginate, sodium bicarbonate, bromelin and essential oils. METHODS: This study enrolled a total of 100 patients affected by functional dyspepsia diagnosed primarily on the basis of typical symptoms and the exclusion of non-functional gastrointestinal diseases (negative upper gastrointestinaltract endoscopy and negative for H...
June 2014: Minerva Gastroenterologica e Dietologica
Alessandro D Genazzani, Susanna Santagni, Federica Ricchieri, Annalisa Campedelli, Erika Rattighieri, Elisa Chierchia, Giulia Marini, Giulia Despini, Alessia Prati, Tommaso Simoncini
AIM: To investigate hormonal dynamics in a group of non-obese polycystic ovary syndrome (PCOS) patients under myo-inositol (MYO) administration. METHODS: Hormonal profiles, insulin response to oral glucose tolerance test (OGTT) and luteinizing hormone (LH) response to gonadotropin-releasing hormone (GnRH) stimulation test before and after the administration of a preparation of MYO (3 g p.o. daily) mixed with lactoferrin and bromelin, in a group (n = 24) of normal weight PCOS patients...
May 2014: Journal of Obstetrics and Gynaecology Research
Patricia Ponce de León, Keydi Juárez Matamoros, Claudia Biondi, Juana Valverde
INTRODUCTION: Sialic acid of the erythrocytes has hemorreologic and hemodynamic importance, so its reduction causes erythrocyte aggregation and low blood flow. OBJECTIVE: To study the effect of A. lumbricoides on the anionic charge of erythrocytes and of desialated erythrocytes, taking the time of contact of the erythrocytes with parasite extracts into account. METHODS: Twenty parasite extracts and Group O erythrocyte suspensions in saline medium (GR) and in bromelin enzymatic medium (GR(b)) were used...
January 2011: Revista Cubana de Medicina Tropical
N A Mazurkova, Iu A Desheva, L N Shishkina, E A Stavskiĭ, L G Rudenko
AIM: To study the optimal conditions for roller cultivation of cold-adapted reassortant vaccine strain of influenza virus A/17/Duck/ Potsdam/86/92 (H5N2) in MDCK and Vero cell cultures grown on nutrient medium based on soy and rice flour hydrolysates obtained using trypsin and bromeline. MATERIALS AND METHODS: Vaccine strain was cultivated on MDCK and Vero cells in rollers in the presence of plant proteases. Obtained culture samples of vaccine strains were lyophilized and their infectivity was assessed...
March 2011: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
N A Mazurkova, Troshkova, L N Shishkina, E A Stavskiĭ, I G Drozdov
AIM: To develop nutrient medium for MDCK and Vero cells based on soy hydrolysate obtained using bromeline and to assess of growth characteristics of influenza virus vaccine strains cultivated on them. MATERIALS AND METHODS: Physico-chemical characteristics of hydrolysate were assessed according to FS 42-3874-99. Growth characteristics of nutrient medium based on soy hydrolysate and vaccine strains of influenza virus A/Solomon Islands/03/06 (H1N1), A/Wisconsin/67/2005 (H3N2) and B/Malaysia/2506/2004 were studied on MDCK and Vero cells...
January 2011: Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii
No abstract text is available yet for this article.
January 1946: Journal of the American Chemical Society
F L Scharf
No abstract text is available yet for this article.
December 7, 1963: Canadian Medical Association Journal
T Winnick, A R Davis, D M Greenberg
1. The rates of heat inactivation of papain, bromelin, and asclepain were determined at several different temperatures. Papain was by far the most resistant to heat. 2. The destruction of papain at 75-83 degrees and bromelin at 55-70 degrees followed the course of a first order reaction, except that for longer times of heating, bromelin (at 60-70 degrees ) was inactivated more rapidly than the first order equation required. 3. The rate of inactivation of asclepain at 55-70 degrees followed the second order equation...
January 20, 1940: Journal of General Physiology
R Pellicano, S Strona, D Simondi, S Reggiani, F Pallavicino, C Sguazzini, A G Bonagura, M Rizzetto, M Astegiano
AIM: Because of the multifactorial pathogenesis of functional dyspepsia, strategies alternative to antacid therapy are being sought for treating the disorder. This prospective study evaluated the benefit of treatment with a dietary integrator composed of sodium alginate, sodium bicarbonate, bromelin and essential oils. METHODS: The study population included 53 consecutive patients (22 males, 31 females; mean age, 54+/-2.5 years) with functional dyspepsia and negative for Helicobacter pylori infection...
September 2009: Minerva Gastroenterologica e Dietologica
Saori Takahashi, Kazuyuki Hori, Mamoru Shinbo, Kazuyuki Hiwatashi, Takeshi Gotoh, Seihan Yamada
We found human renin inhibitory activity in soybean and isolated the active compound, soybean renin inhibitor (SRI). The physico-chemical data on the isolated SRI were identical with those of soyasaponin I. SRI showed significant inhibition against recombinant human renin, with an IC(50) value of 30 microg/ml. Kinetic studies with SRI indicated partial noncompetitive inhibition, with a K(i) value of 37.5 microM. On the other hand, SRI weakly inhibited pepsin, papain, and bromeline activities, but did not inhibit other proteinases, such as trypsin, kallikrein, angiotensin converting enzyme, and aminopeptidase M...
December 2008: Bioscience, Biotechnology, and Biochemistry
Soraia B Calonego, Maria de Lourdes Barjas-Castro, Konradin Metze, Fernanda G Pereira, Irene Lorand-Metze
Red blood cell (RBC) antigens may present changes in density during storage and leukocyte reduction. We evaluated the influence of these variables on FY1, FY2, MNS3 and MNS4 antigens using quantitative flow cytometry (FCM). Forty-eight RBC units were divided into two sub-units each immediately after collection. One of them was leukocyte reduced before storage. Antigen expression was analyzed on days 1 and 35 of storage by gel-centrifugation and FCM. Three RBC samples were submitted to papain and bromelin treatment...
April 2008: Transfusion and Apheresis Science
R H Chittenden
No abstract text is available yet for this article.
November 1893: Journal of Physiology
Teruo Endoh, Daisuke Kobayashi, Naoki Tsuji, Hiromi Tanabe, Saori Koshida, Atsuhito Yagihashi, Naoki Watanabe
BACKGROUND: Although prewarming (PW) can reduce the confounding agglutination of cold-reactive antibodies when testing for warm-reactive antibodies, PW also can adversely affect the detection of warm-reactive antibodies. This study was conducted to determine PW conditions that optimized Rh antibody detection. STUDY DESIGN AND METHODS: In 38 plasma samples with Rh system antibodies detected by any of four methods, and in 8 other samples with cold-reactive antibodies, reactivity was assessed by titer and score...
September 2006: Transfusion
T Tamai, T Mazda
The enzyme test is used to detect certain antibodies or facilitate antibody identification. This study compares antibody reactivity with bromelin-treated red blood cells (RBCs) and untreated RBCs using a newly developed solid-phase immunoassay. The reactivity of irregular antibodies was tested by a magnetic-mixed passive hemagglutination assay (M-MPHA). In addition, antibody reactivity was tested with dried stroma of bromelin-treated RBCs and untreated RBCs (M-MPHA-Dry). Rh antibodies were detected with enzyme-treated intact RBCs and untreated RBCs by M-MPHA...
2001: Immunohematology
V T Ivanova, L V Kordiukova, A A Manykin, E I Burtseva, Iu V Zagorskaia, T A Oskerko, A N Slepushkin
Subviral particles of modern strains of influenza A viruses, i.e. A/New Caledonia/20/99 (H1N1), A/Moscow/10/99 (H3N2), reassortant X-31 (subtype H3N2) and B/Sichuan/379/99, were obtained by using two preparations of bromeline ("Sigma Co., Catalogues' Nos. B2252 and B5144). A selective ability of bromeline B5144 was detected to the proteolytic splitting of hemagglutinin of influenza A and B viruses. An influence of enzyme B5144 produced on influenza B viruses brought about an appearance of subviral particles...
September 2003: Voprosy Virusologii
No abstract text is available yet for this article.
December 1961: American Journal of Clinical Pathology
No abstract text is available yet for this article.
1962: Bibliotheca Haematologica
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