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https://www.readbyqxmd.com/read/28092612/evaluation-of-serum-cytokine-levels-in-recurrent-airway-obstruction
#1
A Niedźwiedź, H Borowicz, K Kubiak, J Nicpoń, P Skrzypczak, Z Jaworski, M Cegielski, J Nicpoń
Recurrent airway obstruction (RAO) represents a serious health problem and is traditionally classified as an allergic disease, where contact with an antigen can induce clinical airway inflammation, bronchial hyper-responsiveness and reversible airway obstruction. Previous studies have demonstrated the presence of the Th2 response in the lungs of human patients with asthma and horses with heaves. These cells are involved in the production of cytokines which regulate the synthesis of immunoglobulins. 40 horses were evaluated: 30 horses with RAO and 10 healthy animals...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092609/horse-expert-an-aided-expert-system-for-diagnosing-horse-diseases
#2
H Qin, J Xiao, X Gao, H Wang
In contrast to the rapid development of the horse husbandry in China, the ability of horse veterinarians to diagnose diseases has not been improved and only a few domain experts have considerable expertise. At present, many expert systems have been developed for diseases diagnosis, but few for horse diseases diagnosis have been studied in depth. This paper presents the design and development of a computer-aided expert system for diagnosing horse diseases. We suggest an approach for diagnosis of horse diseases based on the analysis of diagnostic characteristics and the experiential knowledge of domain experts...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092606/molecular-characterization-and-expression-analysis-of-the-nlr-family-card-containing-five-transcripts-in-the-pig
#3
Q Y Yang, T Chen, Y B Chen, D L Lan
The NOD-like receptor (NLR) family caspase recruitment domain-containing 5 (NLRC5) is one of the newly discovered and largest NLR family members. The NLRC5 has recently received extensive attention because of its important role in regulating innate and adaptive immune responses. The NLRC5 in many vertebrates, such as humans, mice, cattle, and horses, has already been proven and studied. However, the NLRC5 gene characteristics of pigs remain unclear. Thus, we completely cloned the NLRC5 cDNA sequence of the pig using the rapid amplification of cDNA ends(RACE) technology...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092604/replication-kinetics-of-neuropathogenic-and-non-neuropathogenic-equine-herpesvirus-type-1-ehv-1-strains-in-primary-murine-neurons-and-ed-cell-line
#4
J Cymerys, A Słońska, J Brzezicka, A Tucholska, A Chmielewska, J Rola, P Malik, M W Bańbura
Equine herpesvirus type 1 (EHV-1) causes respiratory infections, abortion and neurological disorders in horses. Molecular epidemiology studies have demonstrated that a single-point mutation in DNA polymerase gene, resulting in an amino acid variation (N752/D752), is significantly associated with the neuropathogenic potential of EHV-1 strains. The aim of the study was to elucidate if there are any differences between neuropathogenic (EHV-1 26) and non-neuropathogenic (Jan-E and Rac-H) EHV-1 strains in their ability to infect neuronal cells...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092600/influence-of-horse-breed-on-transepidermal-water-loss
#5
M P Szczepanik, P M Wilkołek, Ł R Adamek, M Pluta, M Gołyński, W Sitkowski, G Kalisz, I Taszkun, Z J H Pomorski
Non-invasive methods of skin condition assessment include, among others, the evaluation of transepidermal water loss (TEWL). The aim of the study was to examine whether TEWL values depend on horse breed. The study was conducted on four breeds: "Felin" ponies (FP) (n=16), Polish koniks (PK) (n=15), Polish cold-blooded horses (PcbH) (n=11) and Wielkopolska horses (WH) (n=12). It was found that horse breed influences TEWL values. In the neck region, statistically significant differences were found between PK and FP (p=0...
December 1, 2016: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28092108/pharmacokinetics-and-pharmacodynamics-of-the-injectable-formulation-of-methadone-hydrochloride-and-methadone-in-lipid-nanocarriers-administered-orally-to-horses
#6
N Crosignani, S P Luna, T Dalla Costa, E L Pimenta, C B Detoni, S S Guterres, J N Puoli Filho, J C Pantoja, M C Pigatto
We investigated the thermal, electrical and mechanical antinociceptive and physiological effects (heart rate, respiratory rate, arterial blood pressure, head height and abdominal auscultation score), and pharmacokinetics, of 0.5 mg/kg of the injectable formulation (ORAL) or nanoparticulated methadone (NANO) given orally, in six adult mares, using a crossover, blind and prospective design. Repeated-measure models were used to compare parametric data between and within treatments, followed by Tukey's test. Nonparametric data were analysed with Wilcoxon signed-rank, adjusted by Bonferroni tests...
January 16, 2017: Journal of Veterinary Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28091706/microclimates-might-limit-indirect-spillover-of-the-bat-borne-zoonotic-hendra-virus
#7
Gerardo Martin, Rebecca J Webb, Carla Chen, Raina K Plowright, Lee F Skerratt
Infectious diseases are transmitted when susceptible hosts are exposed to pathogen particles that can replicate within them. Among factors that limit transmission, the environment is particularly important for indirectly transmitted parasites. To try and assess a pathogens' ability to be transmitted through the environment and mitigate risk, we need to quantify its decay where transmission occurs in space such as the microclimate harbouring the pathogen. Hendra virus, a Henipavirus from Australian Pteropid bats, spills-over to horses and humans, causing high mortality...
January 14, 2017: Microbial Ecology
https://www.readbyqxmd.com/read/28090706/western-blot-analysis-of-sera-from-dogs-with-suspected-food-allergy
#8
Claude Favrot, Monika Linek, Jacques Fontaine, Luc Beco, Ana Rostaher, Nina Fischer, Nicolas Couturier, Sandrine Jacquenet, Bernard E Bihain
BACKGROUND: Food allergy is often suspected in dogs with clinical signs of atopic dermatitis. This diagnosis is confirmed with an elimination diet and a subsequent challenge with regular food. Laboratory tests for the diagnosis of food allergy in dogs are unreliable and/or technically difficult. Cyno-DIAL(®) is a Western blot method that might assist with the selection of an appropriate elimination diet. HYPOTHESIS/OBJECTIVES: To evaluate the performance of Cyno-DIAL(®) for the selection of an elimination diet and diagnosis of food allergy...
January 16, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28088897/multiplex-pcr-as-a-rapid-and-sensitive-method-for-identification-of-meat-species-in-halal-meat-products
#9
Mahsa Alikord, Javad Keramat, Mahdi Kadivar, Hassan Momtaz, Mohammad Naghi Eshtiaghi, Aziz Homayouni Rad
BACKGROUND: Species identification and authentication in meat products are important subjects for ensuring the health of consumers. The multiplex-PCR amplification and species-specific primer set were used for identification of horse, donkey, pig and other ruminants in raw and processed meat products. METHODS: Oligonucleotid primers were designed for amplification of species-specific mitochondrial DNA sequences of each species and samples were prepared from binary meat mixtures...
January 13, 2017: Recent Patents on Food, Nutrition & Agriculture
https://www.readbyqxmd.com/read/28087984/challenges-in-detecting-substances-for-equine-anti-doping
#10
REVIEW
A G Fragkaki, N Kioukia-Fougia, P Kiousi, M Kioussi, M Tsivou
The artificial increase of the physical capability of horses using drugs is well-known in racing and in other equine sports. Both illicit and therapeutic substances are regarded as prohibited substances in competition in most countries. Some countries do make distinctions for a few, specific drugs which are, however, allowed for use in other countries. The primary objective in the case of doping control is the detection of any trace of drug exposure, either parent drug or any of its metabolites, using the most powerful analytical methods which generally are based on chromatographic/mass spectrometric techniques...
January 14, 2017: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28087751/odyssey-escape-is-pcsk9-inhibition-the-trojan-horse-for-the-use-of-lipoprotein-apheresis-in-familial-hypercholesterolaemia
#11
EDITORIAL
Gerald F Watts, Claudia Stefanutti
No abstract text is available yet for this article.
December 21, 2016: European Heart Journal
https://www.readbyqxmd.com/read/28081146/maternal-nutrition-during-pregnancy-affects-testicular-and-bone-development-glucose-metabolism-and-response-to-overnutrition-in-weaned-horses-up-to-two-years
#12
Morgane Robles, Camille Gautier, Luis Mendoza, Pauline Peugnet, Cédric Dubois, Michèle Dahirel, Jean-Philippe Lejeune, Isabelle Caudron, Isabelle Guenon, Sylvaine Camous, Anne Tarrade, Laurence Wimel, Didier Serteyn, Hélène Bouraima-Lelong, Pascale Chavatte-Palmer
INTRODUCTION: Pregnant mares and post-weaning foals are often fed concentrates rich in soluble carbohydrates, together with forage. Recent studies suggest that the use of concentrates is linked to alterations of metabolism and the development of osteochondrosis in foals. The aim of this study was to determine if broodmare diet during gestation affects metabolism, osteoarticular status and growth of yearlings overfed from 20 to 24 months of age and/or sexual maturity in prepubertal colts...
2017: PloS One
https://www.readbyqxmd.com/read/28079932/the-trojan-horse-coronatine-the-coi1-jaz2-myc2-3-4-anac019-055-072-module-in-stomata-dynamics-upon-bacterial-infection
#13
Claus Wasternack
No abstract text is available yet for this article.
February 2017: New Phytologist
https://www.readbyqxmd.com/read/28079926/fallen-stock-data-an-essential-source-of-information-for-quantitative-knowledge-of-equine-mortality-in-france
#14
J Tapprest, E Morignat, X Dornier, M Borey, P Hendrikx, B Ferry, D Calavas, C Sala
BACKGROUND: Quantitative information about equine mortality is relatively scarce, yet it could be of great value for epidemiological purposes. In France, data from rendering plants are centralised in the Fallen Stock Data Interchange database (FSDI), managed by the French Ministry of Agriculture, while individual equine data are centralised in the French equine census database, SIRE, managed by the French horse and riding institute (IFCE). OBJECTIVES: To evaluate whether the combined use of the FSDI and the SIRE databases can provide representative and accurate quantitative information on mortality for the French equine population, and to propose enhancements of these databases to improve the quality of the resulting demographic information...
January 12, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28079277/whole-body-vibration-exposure-of-occupational-horseback-riding-in-agriculture-a-ranching-example
#15
Xiaoke Zeng, Catherine Trask, Aaron M Kociolek
BACKGROUND: Horse riding is common in many occupations; however, there is currently no research evaluating exposure to whole-body vibration and mechanical shock on horseback. METHODS: Whole-body vibration was measured on a cattle rancher during two 30 min horseback rides using a tri-axial accelerometer mounted on a western saddle. Vibration was summarized into standardized metrics, including the 8 hr equivalent root-mean-squared acceleration (A[8]) and the daily 4th power vibration dose value (VDV)...
February 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28078757/lamellar-events-related-to-insulin-like-growth-factor-1-receptor-signaling-in-two-models-relevant-to-endocrinopathic-laminitis
#16
H E Lane, T A Burns, O C Hegedus, M R Watts, P S Weber, K A Woltman, R J Geor, L J McCutcheon, S C Eades, L E Mathes, J K Belknap
BACKGROUND: Insulin dysregulation, obesity, and exposure to high-non structural carbohydrate (NSC) forage are risk factors for equine metabolic syndrome (EMS)-associated laminitis (EMSAL); high systemic insulin concentrations in EMSAL are proposed to induce cellular dysregulation in the digital lamellae through activation of the IGF-1 receptor. OBJECTIVES: To use a dietary challenge model (DCM) and a euglycemic hyperinsulinemic clamp (EHC) model to assess lamellar growth factor-related signaling...
January 11, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28078653/meta-analysis-of-treatment-with-rabbit-and-horse-antithymocyte-globulin-for-aplastic-anemia
#17
Jin Hayakawa, Junya Kanda, Yu Akahoshi, Naonori Harada, Kazuaki Kameda, Tomotaka Ugai, Hidenori Wada, Yuko Ishihara, Koji Kawamura, Kana Sakamoto, Masahiro Ashizawa, Miki Sato, Kiriko Terasako-Saito, Shun-Ichi Kimura, Misato Kikuchi, Rie Yamazaki, Shinichi Kako, Yoshinobu Kanda
Aplastic anemia patients who received rabbit antithymocyte globulin exhibited response and survival rates inferior to those who received horse antithymocyte globulin in several studies. Therefore, we conducted a meta-analysis to compare rabbit and horse antithymocyte globulin as immunosuppressive therapy for aplastic anemia. We searched online databases for studies that compared antithymocyte globulin regimens as first-line treatment for aplastic anemia, including both randomized and non-randomized controlled trials...
January 11, 2017: International Journal of Hematology
https://www.readbyqxmd.com/read/28077887/examination-of-the-predictive-power-of-electromyography-and-urodynamic-study-in-patients-with-cauda-equina-syndrome-horse-tail-syndrome
#18
Mohammadreza Shahmohammadi, Reza Jalil Khoshuod, Alireza Zali, Amir Saied Seddeghi, Nima Mohseni Kabir
BACKGROUND: Cauda equina syndrome is a rare disorder that causes loss of Lumbar plexus function (nerve roots) lower than conus medullaris. No risk factor has been defined for this disease yet. Due to the high morbidity of Cauda equina syndrome and lack of sufficient information about the connection between the disease and urodynamic findings and EMG (Electromyography) findings, the need for this comprehensive study is felt. OBJECTIVE: The aim is to determine the predictive power of findings resulted from urodynamics and electromyography of perineal region and around sphincter in the clinical cure rate of urination in patients with urinary retention followed by Cauda equina syndrome...
October 2016: Acta Informatica Medica: AIM
https://www.readbyqxmd.com/read/28077153/detection-of-strongylus-vulgaris-in-equine-faecal-samples-by-real-time-pcr-and-larval-culture-method-comparison-and-occurrence-assessment
#19
A Kaspar, K Pfister, M K Nielsen, C Silaghi, H Fink, M C Scheuerle
BACKGROUND: Strongylus vulgaris has become a rare parasite in Germany during the past 50 years due to the practice of frequent prophylactic anthelmintic therapy. To date, the emerging development of resistance in Cyathostominae and Parascaris spp. to numerous equine anthelmintics has changed deworming management and the frequency of anthelmintic usage. In this regard, reliable detection of parasitic infections, especially of the highly pathogenic S. vulgaris is essential. In the current study, two diagnostic methods for the detection of infections with S...
January 11, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28075596/yeast-microcapsule-mediated-targeted-delivery-of-diverse-nanoparticles-for-imaging-and-therapy-via-the-oral-route
#20
Xing Zhou, Xiangjun Zhang, Songling Han, Yin Dou, Mengyu Liu, Lin Zhang, Jia Wei Guo, Qing Shi, Genghao Gong, Ruibing Wang, Jiang Hu, Xiaohui Li, Jianxiang Zhang
Targeting of nanoparticles to distant diseased sites after oral delivery remains highly challenging, due to the existence of many biological barriers in the gastrointestinal tract. Here we report targeted oral delivery of diverse nanoparticles in multiple disease models, via a 'Trojan horse' strategy based on a bioinspired yeast capsule (YC). Diverse charged nanoprobes including quantum dots (QDs), iron oxide nanoparticles (IONPs), and assembled organic fluorescent nanoparticles can be effectively loaded into YC through electrostatic force-driven spontaneous deposition, resulting in different diagnostic YC assemblies...
January 11, 2017: Nano Letters
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