keyword
MENU ▼
Read by QxMD icon Read
search

Structural competency

keyword
https://www.readbyqxmd.com/read/28931248/validity-evidence-for-the-neuro-endoscopic-ventriculostomy-assessment-tool-nevat
#1
Gerben E Breimer, Faizal A Haji, Giuseppe Cinalli, Eelco W Hoving, James M Drake
BACKGROUND: Growing demand for transparent and standardized methods for evaluating surgical competence prompted the construction of the Neuro-Endoscopic Ventriculostomy Assessment Tool (NEVAT). OBJECTIVE: To provide validity evidence of the NEVAT by reporting on the tool's internal structure and its relationship with surgical expertise during simulation-based training. METHODS: The NEVAT was used to assess performance of trainees and faculty at an international neuroendoscopy workshop...
February 1, 2017: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/28929762/modulating-the-performance-of-an-asymmetric-organocatalyst-by-tuning-its-spatial-environment-in-a-metal-organic-framework
#2
Lujia Liu, Tian-You Zhou, Shane G Telfer
Systematically tuning the spatial environment around the active sites of synthetic catalysts is a difficult challenge. Here, we show how this can be accomplished in the pores of multicomponent metal-organic frameworks. This relies on embedding a catalytic unit in a pore of the MUF-77 framework and then tuning its environment by introducing different functional groups to the surrounding linkers. This approach benefits from the structural regularity of MUF-77, which places each component in a precise location to circumvent disorder...
September 20, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28928938/the-elixir-excelerate-train-the-trainer-pilot-programme-empower-researchers-to-deliver-high-quality-training
#3
Sarah L Morgan, Patricia M Palagi, Pedro L Fernandes, Eija Koperlainen, Jure Dimec, Diana Marek, Lee Larcombe, Gabriella Rustici, Teresa K Attwood, Allegra Via
One of the main goals of the ELIXIR-EXCELERATE project from the European Union's Horizon 2020 programme is to support a pan-European training programme to increase bioinformatics capacity and competency across ELIXIR Nodes. To this end, a Train-the-Trainer (TtT) programme has been developed by the TtT subtask of EXCELERATE's Training Platform, to try to expose bioinformatics instructors to aspects of pedagogy and evidence-based learning principles, to help them better design, develop and deliver high-quality training in future...
2017: F1000Research
https://www.readbyqxmd.com/read/28927677/std-nmr-experiments-identify-a-structural-motif-with-novel-second-site-activity-against-west-nile-virus-ns2b-ns3-protease
#4
Tobias Schöne, Lena Lisbeth Grimm, Naoki Sakai, Linlin Zhang, Rolf Hilgenfeld, Thomas Peters
West Nile virus (WNV) belongs to the genus Flavivirus of the family Flaviviridae. This mosquito-borne virus that is highly pathogenic to humans has been evolving into a global threat during the past two decades. Despite many efforts, neither antiviral drugs nor vaccines are available. The viral protease NS2B-NS3(pro) is essential for viral replication, and therefore it is considered a prime drug target. However, success in the development of specific NS2B-NS3(pro) inhibitors had been moderate so far. In the search for new structural motifs with binding affinity for NS2B-NS3(pro), we have screened a fragment library, the Maybridge Ro5 library, employing saturation transfer difference (STD) NMR experiments as readout...
September 16, 2017: Antiviral Research
https://www.readbyqxmd.com/read/28926408/serum-glycan-binding-igg-antibodies-in-hiv-1-infection-and-during-the-development-of-broadly-neutralizing-responses
#5
Cathrine Scheepers, Sudipa Chowdhury, W Shea Wright, Christopher T Campbell, Nigel J Garrett, Quarraisha Abdool Karim, Salim S Abdool Karim, Penny L Moore, Jeffrey C Gildersleeve, Lynn Morris
BACKGROUND: The HIV-1 envelope is covered with glycans that provide structural integrity and protect conserved regions from host antibody responses. However, these glycans are often the target of broadly neutralizing antibodies (bNAbs) that emerge in some HIV infected individuals. We aimed to determine whether anti-glycan IgG antibodies are a general response to HIV-1 infection or specific to individuals who develop bNAbs. METHODS: IgG binding to glycans was assessed using arrays that contained 245 unique components including N-linked carbohydrates, glycolipids and Tn-peptides...
September 18, 2017: AIDS
https://www.readbyqxmd.com/read/28926242/structure-function-studies-of-artemisia-tridentata-farnesyl-diphosphate-synthase-and-chrysanthemyl-diphosphate-synthase-by-site-directed-mutagenesis-and-morphogenesis
#6
J Scott Lee, Jian-Jung Pan, Gurusankar Ramamoorthy, C Dale Poulter
The amino acid sequences of farnesyl diphosphate synthase (FPPase) and chrysanthemyl diphosphate synthase (CPPase) from Artemisia tridentata ssp. Spiciformis, minus their chloroplast targeting regions, are 71% identical and 90% similar. FPPase efficiently and selectively synthesizes the "regular" sesquiterpenoid farnesyl diphosphate (FPP) by coupling isopentenyl diphosphate (IPP) to dimethylallyl diphosphate (DMAPP) and then to geranyl diphosphate (GPP). In contrast, CPPase is an inefficient promiscuous enzyme, which synthesizes the "irregular" monoterpenes chrysanthemyl diphosphate (CPP), lavandulyl diphosphate (LPP), and trace quantities of maconelliyl diphosphate (MPP) from two molecules of DMAPP, in addition to coupling IPP to DMAPP...
September 19, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28925571/human-factors-and-simulation-in-emergency-medicine
#7
Emily M Hayden, Ambrose H Wong, Jeremy Ackerman, Margaret K Sande, Charles Lei, Leo Kobayashi, Michael Cassara, Dylan D Cooper, Kimberly Perry, William E Lewandowski, Mark W Scerbo
This consensus group from the 2017 Academic Emergency Medicine Consensus Conference "Catalyzing System Change through Health Care Simulation: Systems, Competency, and Outcomes" held in Orlando, Florida on May 16, 2017 focused on the use of human factors and simulation in the field of emergency medicine. The human factors discipline is often underutilized within emergency medicine but has significant potential in improving the interface between technologies and individuals in the field. The discussion explored the domain of human factors, its benefits in medicine, how simulation can be a catalyst for human factors work in emergency medicine, and how emergency medicine can collaborate with human factors professionals to affect change...
September 19, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28925520/rational-design-of-bifunctional-2-fold-interpenetrated-zn-ii-metal-organic-framework-for-selective-adsorption-of-co2-and-efficient-aqueous-phase-sensing-of-2-4-6-trinitrophenol
#8
C M Nagaraja, Sandeep Dhankhar, Nayuesh Sharma, Sandeep Kumar, Dhilip Kumar
A bifunctional, microporous Zn(II) metal-organic framework, [Zn2(NH2BDC)2(dpNDI)]n (MOF1) (where, NH2BDC =2-aminoterephthalic acid, dpNDI =N,N'-di(4-pyridyl)-1,4,5,8-naphthalenediimide) has been synthesized solvothermally. MOF1 shows a 2-fold interpenetrated, 3D pillar-layered framework structure composed of two types of 1D channels with dimensions of ~3.80 x 16.9 Å2 and 7.49 x 17.01 Å2 decorated with pendent -NH2 group. Owing to the presence of basic functionalized pore surface, MOF1 exhibits selective adsorption of CO2 with high value of heat of adsorption (Qst = 46...
September 19, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28923521/why-do-people-with-mental-distress-have-poor-social-outcomes-four-lessons-from-the-capabilities-approach
#9
Richard Brunner
Macro level data indicate that people experiencing mental distress experience poor health, social and economic outcomes. The sociology of mental health has a series of dominant competing explanations of the mechanisms at personal, social and structural levels that generate these poor outcomes. This article explains the limitations of these approaches and takes up the challenge of Hopper (2007) who in this journal proposed the capabilities approach as a means of normatively reconceptualising the experiences of people with mental distress, with a renewed focus on agency, equality and genuine opportunity...
September 8, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28922022/implementing-a-collaborative-coaching-intervention-for-professionals-providing-care-to-children-and-their-families-an-exploratory-study
#10
Sandy K Tatla, Dori Howard, Alda Antunes Silvestre, Stacey Burnes, Meghan Husson, Tal Jarus
The growing complexity of healthcare requires family and interprofessional partnerships to deliver effective care. Interprofessional coaching can enhance family-centred practice and collaboration. The purpose of this study was to explore the acceptability and feasibility of collaborative coaching training to improve family centredness within acute paediatric rehabilitation. Using a participatory action design, service providers (SPs; n = 36) underwent a 6-month coaching programme involving coaching workshops, learning triads, and tailored sessions with a licensed coach...
September 18, 2017: Journal of Interprofessional Care
https://www.readbyqxmd.com/read/28920422/dual-activator-codoped-upconversion-nanoprobe-with-core-multishell-structure-for-in-vitro-and-in-vivo-detection-of-hydroxyl-radical
#11
Xin-Yue Song, Jiayu Zhang, Zihong Yue, Zonghua Wang, Zhihong Liu, Shusheng Zhang
Monitoring the fluctuation of hydroxyl radical (•OH) in the body can serve as an effective tool for the prediction of relative diseases, which, however, is highly challenging due to its short lifetime, high reactivity and extremely low concentration. Sandwich structured lanthanide-doped upconversion nanoparticles (UCNPs) exhibit unique luminescence properties and great prospects in bioimaging. Nonetheless, their rather low luminescence efficiency and intensity are serious limitations for their application...
September 18, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28918810/progress-in-endoscopic-ultrasonography-training-in-therapeutic-or-interventional-endoscopic-ultrasonography
#12
REVIEW
Monica Saumoy, Michel Kahaleh
Therapeutic endoscopic ultrasound is a rapidly expanding field, requiring training beyond the 3-year gastroenterology fellowship and at least an additional year in a structured advanced endoscopy fellowship program with mentorship from an expert at a sufficiently high-volume center. Simulation models can provide initial instruction on technique and increase familiarity with the rapidly changing devices. Trainees must also be given a graduated level of independence to perform each step and, eventually, be able to practice on a variety of endoscopic targets...
October 2017: Gastrointestinal Endoscopy Clinics of North America
https://www.readbyqxmd.com/read/28918381/assessing-decisional-capacity-for-research-participation-in-psychiatric-patients-and-their-relatives
#13
Donae Elizabeth George, Saumil Dholakia, Prathap Tharyan
A cross-sectional study among adult inpatients with non-organic psychiatric disorders, and among their key relatives, assessed their comprehension and recall of key information in consent forms. It also assessed their capacity to consent to participate in two hypothetical randomised controlled trials (RCTs) with different potential risks and burdens, using structured questionnaires and recorded interviews. Of the 24 participants (12 patient-key relative dyads), seven patients (58%) and three key relatives (25%) were clinically judged to lack the capacity to consent...
August 8, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28918322/time-for-tiger-to-roar-technology-informatics-guiding-education-reform
#14
EDITORIAL
Siobhan O'Connor, Ursula Hubner, Toria Shaw, Rachelle Blake, Marion Ball
Information Technology (IT) continues to evolve and develop with electronic devices and systems becoming integral to healthcare in every country. This has led to an urgent need for all professions working in healthcare to be knowledgeable and skilled in informatics. The Technology Informatics Guiding Education Reform (TIGER) Initiative was established in 2006 in the United States to develop key areas of informatics in nursing. One of these was to integrate informatics competencies into nursing curricula and life-long learning...
August 19, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28917856/the-effect-of-ionic-and-non-ionic-surfactants-and-ph-on-the-stability-adsorption-and-electrokinetic-properties-of-the-alginic-acid-alumina-system
#15
E Grządka, J Matusiak
The influence of ionic (CTAB; SDS) and non-ionic (TX-100; TX-165 and TX-405) surfactants as well as pH of the solution on the stability, adsorption and electrokinetic properties of the alginic acid (AA)/alumina (Al2O3) suspensions was studied. The results obtained using the spectrophotometric method show that the addition of ionic surfactants is an effective way to obtain stable AA/Al2O3 suspensions whereas the changes in pH are not sufficient. Surface tension measurements together with the adsorption data show that the macromolecules of alginic acid are able to form complexes with CTAB, however, they compete for the adsorption centers on the metal oxide surface with SDS...
November 1, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/28917603/development-of-the-nurses-care-coordination-competency-scale-for-mechanically-ventilated-patients-in-critical-care-settings-in-japan-part-1-development-of-a-measuring-instrument
#16
Chie Takiguchi, Yumiko Yatomi, Tomoko Inoue
OBJECTIVES: To develop a draft scale measuring nurses' care coordination competency for care of mechanically ventilated patients in critical care settings. METHOD: The scale items and concepts were derived from semi-structured interviews with 28 professionals (14 nurses, eight physicians, three physical therapists, three clinical engineers) who are managing mechanically ventilated critical care patients. A grounded theory approach was used. After content validation by experts, two pilot tests were used to identify and correct non-discriminating items and vague items...
September 13, 2017: Intensive & Critical Care Nursing: the Official Journal of the British Association of Critical Care Nurses
https://www.readbyqxmd.com/read/28915949/assessment-of-surgical-skills-and-competency
#17
REVIEW
Nasir I Bhatti
Evaluation of surgical skills and competency are important aspects of the medical education process. Measurable and reproducible methods of assessment with objective feedback are essential components of surgical training. Objective Structured Assessment of Technical Skills (OSATS) is widely used across the medical specialties and otolaryngology-specific tools have been developed and validated for sinus and mastoid surgery. Although assessment of surgical skills can be time-consuming and requires human and financial resources, new evaluation methods and emerging technology may alleviate these barriers while also improving data collection practices...
October 2017: Otolaryngologic Clinics of North America
https://www.readbyqxmd.com/read/28915815/designing-an-implementation-intervention-with-the-behaviour-change-wheel-for-health-provider-smoking-cessation-care-for-australian-indigenous-pregnant-women
#18
Gillian S Gould, Yael Bar-Zeev, Michelle Bovill, Lou Atkins, Maree Gruppetta, Marilyn J Clarke, Billie Bonevski
BACKGROUND: Indigenous smoking rates are up to 80% among pregnant women: prevalence among pregnant Australian Indigenous women was 45% in 2014, contributing significantly to the health gap for Indigenous Australians. We aimed to develop an implementation intervention to improve smoking cessation care (SCC) for pregnant Indigenous smokers, an outcome to be achieved by training health providers at Aboriginal Medical Services (AMS) in a culturally competent approach, developed collaboratively with AMS...
September 15, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28915377/midwives-%C3%A2-experiences-of-caring-for-pregnant-women-admitted-to-ebola-centres-in-sierra-leone
#19
REVIEW
Elin Erland, Bente Dahl
OBJECTIVE: to explore and describe midwives' experiences of caring for pregnant women admitted to Ebola centres in Sierra Leone. DESIGN: a qualitative interview study with an exploratory and descriptive approach. SETTING: individual semi-structured interviews with midwives who provided care for pregnant woman in eight different Ebola centres in Sierra Leone during the Ebola outbreak in 2014-16. PARTICIPANTS: 11 midwives, Sierra Leoneans and expatriates, who worked for three different humanitarian organisations in Sierra Leone during the Ebola outbreak in 2014-2016...
September 1, 2017: Midwifery
https://www.readbyqxmd.com/read/28914537/coupling-bioflocculation-of-dehalococcoides-mccartyi-to-high-rate-reductive-dehalogenation-of-chlorinated-ethenes
#20
Anca G Delgado, Devyn Fajardo-Williams, Emily Bondank, Sofia Esquivel-Elizondo, Rosa Krajmalnik-Brown
Continuous bioreactors operated at low hydraulic retention times have rarely been explored for reductive dehalogenation of chlorinated ethenes. The inability to consistently develop such bioreactors affects the way growth approaches for Dehalococcoides mccartyi bioaugmentation cultures are envisioned. It also affects interpretation of results from in situ continuous treatment processes. We report bioreactor performance and dehalogenation kinetics of a D. mccartyi-containing consortium in an upflow bioreactor...
September 15, 2017: Environmental Science & Technology
keyword
keyword
51331
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"