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Microwave Ablation

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https://www.readbyqxmd.com/read/29123005/percutaneous-ablation-for-hepatocellular-carcinoma-and-peritoneal-dialysis
#1
Annabel Boyer, Marc-Antoine Jegonday, Antoine Lanot, Maxence Ficheux, Thierry Lobbedez, Clémence Bechade
Hepatocellular carcinoma (HCC) is the second leading cause of death by cancer worldwide. Resection and liver transplantation are the gold standards, but only a minority of people are eligible. Percutaneous ablation therapies, such as microwave ablation (MWA), have consequently been developed. There is a lack of guidelines regarding the treatment of HCCs in end-stage renal disease (ESRD) patients. Here, we report the case of a 67-year-old patient who was undergoing peritoneal dialysis (PD) for chronic congestive heart failure and who presented with an HCC while undergoing PD...
November 2017: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29108354/ultrasound-guided-percutaneous-microwave-ablation-assisted-by-three-dimensional-visualization-operative-treatment-planning-system-and-percutaneous-transhepatic-cholangial-drainage-with-intraductal-chilled-saline-perfusion-for-larger-hepatic-hilum-hepatocellular
#2
Xin Li, Jie Yu, Ping Liang, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Shaobo Duan, Jiasheng Zheng
To assess the clinical efficiency of ultrasound-guided percutaneous microwave ablation (US-PMWA) assisted by three-dimensional (3D) visualization operative treatment planning system and percutaneous transhepatic cholangial drainage with intraductal chilled saline perfusion (PTCD-ICSP) for larger hepatic hilum hepatocellular carcinoma (HH-HCC) (D ≥ 3 cm). The combination therapy was performed in 14 patients from Sep 2011 to May 2017. The major outcomes for assessment were biliary duct complications, local tumor recurrence, distant recurrence and overall survival rates...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29108316/ultrasound-guided-percutaneous-microwave-ablation-of-benign-breast-lesions
#3
Jie Yu, Bao-Hua Chen, Jing Zhang, Zhi-Yu Han, Han Wu, Yan Huang, Meng-Juan Mu, Ping Liang
The benign breast lesions (BBLs) share a high incidence for women and therapy methods with minimal invasion and better cosmetic outcome are thirsted for. In this study, 122 patients with 198 biopsy-proved BBLs were enrolled. Ultrasound (US)-guided microwave ablation (MWA) was performed with local anesthesia from November, 2013 to April, 2016. The mean longest tumor size assessed was 1.6±0.7 cm (ranging 0.7-4.9 cm). MWA was successfully performed in all cases including 85 lesions adjacent to the skin, pectoralis and areola...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29108305/ct-guided-microwave-ablation-through-the-lungs-for-treating-liver-tumors-near-the-diaphragm
#4
Han Qi, Hao Zhang, Chao Wan, Lin Xie, Ze Song, Weijun Fan
Purpose: To explore the short-term efficacy and safety of CT-guided microwave ablation (MWA) for treating liver tumors near the diaphragm. Results: The complete response (CR) rate for CT-guided MWA through the lung was 94.7% (124/131). The incomplete response (ICR) rate was 5.3% (7/131), of which 6 patients with ICRs achieved CRs after MWA. The CR rate for Group I was higher than Group II (99.0% vs. 80.0%, P=0.001). The mean follow-up time was 11.2 ±7.50 months...
October 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29101952/a-radiologist-s-view-of-tumor-ablation-in-the-radiology-suite
#5
REVIEW
Sharath K Bhagavatula, Jason Lane, Paul Shyn
Image-guided percutaneous, minimally invasive ablation techniques offer a wide variety of new modalities to treat tumors in some of the most medically complicated patients coming to our hospitals. The use of computed tomography, PET, ultrasound imaging, and MRI to guide radiofrequency ablation, microwave ablation, and cryoablation techniques now makes it possible to treat patients on a short stay or outpatient basis with very good immediate outcomes. This rapid expansion of new tumor ablation techniques often presents challenges for the non-operating room anesthesia team...
December 2017: Anesthesiology Clinics
https://www.readbyqxmd.com/read/29096566/perivascular-extension-of-microwave-ablation-zone-demonstrated-using-an-ex-vivo-porcine-perfusion-liver-model
#6
Saurabh Singh, Pulathis Nilantha Siriwardana, Edward William Johnston, Jennifer Watkins, Steve Bandula, Rowland Illing, Brian Ritchie Davidson
Microwave ablation (MWA) has been proposed to suffer less from the heat sink effect compared to radiofrequency ablation but has been reported to cause extension of the ablation zone along intrahepatic vessels in clinical practice. To study this effect in detail, eight fresh porcine livers were perfused in an ex-vivo organ perfusion system. Livers were perfused with oxygenated, O-positive human blood at 37°C. Perfusion was discontinued immediately before ablation in the non-perfused group (n = 4) whilst in the perfused group (n = 4) perfusion was maintained during MWA (140W X 2min)...
November 2, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29096018/massive-fatal-pulmonary-haemorrhage-during-bevacizumab-treatment-following-microwave-ablation-therapy-for-oligometastatic-lung-metastasis-from-rectal-cancer
#7
Thiru Prasanna, Greg Briggs, Sanjiv Jain, Desmond Yip
Although thoracic ablative therapies are generally safe procedures, fatal complications can occur. Bevacizumab is a standard-of-care treatment along with chemotherapy for metastatic colorectal cancer. Although uncommon, unpredictable serious adverse events can occur secondary to bevacizumab. We report a case of fatal intrapulmonary haemorrhage as a result of arteriopulmonary fistula in a patient after microwave ablation of pulmonary colorectal cancer metastasis while on bevacizumab. Antiangiogenetic properties of bevacizumab are associated with delayed wound healing, which might have been a crucial factor in the development of arteriopulmonary fistula and haemorrhage...
October 31, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29082799/the-efficacy-and-safety-of-microwave-ablation-in-patients-with-retroperitoneal-metastases
#8
Zhigang Wei, Xin Ye, Xia Yang, Aimin Zheng, Guanghui Huang, Shenming Dong, Wenhong Li, Jiao Wang, Xiaoying Han, Min Meng, Yang Ni
BACKGROUND: Retroperitoneal metastases are common, and most present with symptoms; however, treatments for this condition are limited. This retrospective study verified the efficacy and safety of microwave ablation (MWA) in retroperitoneal metastases patients. METHODS: Patients with pathologically confirmed malignant carcinoma and imaging showing retroperitoneal metastases were enrolled and underwent MWA. The end-points included objective response rate, time to local progression (TTLP), overall survival, visual analogue scale (VAS) score, dose of morphine pre- and post-ablation and complications...
October 30, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29066127/in-vivo-percutaneous-microwave-ablation-in-kidneys-correlation-with-ex-vivo-data-and-ablation-work
#9
C Marcelin, J Leiner, S Nasri, F Petitpierre, Y Le Bras, M Yacoub, N Grenier, J C Bernhard, F Cornelis
PURPOSE: To compare diameters of in vivo microwave ablation (MWA) performed in swine kidneys with ex vivo diameters, and to correlate with ablation work (AW), a new metric reflecting total energy delivered. MATERIAL AND METHODS: Eighteen in vivo MWA were performed in 6 swine kidneys successively using one or two antennas (MicroThermX(®)). Ablation consisted in delivering power (45-120W) for 5-15minutes. Ex vivo diameters were provided by the vendors and obtained on bovine liver tissue...
October 21, 2017: Diagnostic and Interventional Imaging
https://www.readbyqxmd.com/read/29055338/examining-transition-metal-hydrosulfides-the-pure-rotational-spectrum-of-znsh-x%C3%AC-2-a
#10
M P Bucchino, G R Adande, D T Halfen, L M Ziurys
The pure rotational spectrum of the ZnSH (X̃(2)A') radical has been measured using millimeter-wave direct absorption and Fourier transform microwave (FTMW) methods across the frequency range 18-468 GHz. This work is the first gas-phase detection of ZnSH by any spectroscopic technique. Spectra of the (66)ZnSH, (68)ZnSH, and (64)ZnSD isotopologues were also recorded. In the mm-wave study, ZnSH was synthesized in a DC discharge by the reaction of zinc vapor, generated by a Broida-type oven, with H2S; for FTMW measurements, the radical was made in a supersonic jet expansion by the same reactants but utilizing a discharge-assisted laser ablation source...
October 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29049221/percutaneous-microwave-ablation-liver-partition-and-portal-vein-embolization-for-planned-hepatectomy-due-to-large-gastrointestinal-stromal-tumor-metastases-a-case-report
#11
Jie Liu, Chengwu Zhang, Defei Hong, Minjie Shang, Weifeng Yao, Yuan Chen
RATIONALE: The liver is the most frequent site of relapse of gastrointestinal stromal tumors (GISTs). Surgery is always considered to be unsuitable because of the multiple metastases. PATIENT CONCERNS: In this report, we describe a case of large, multiple GIST liver metastases that were treated with percutaneous microwave ablation liver partition and portal vein embolization for planned hepatectomy (PALPP). A 44-year-old woman had undergone pancreaticoduodenectomy 4 years previously because of the diagnosis of a large duodenal GIST...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29042794/comparison-of-microwave-ablation-and-hepatic-resection-for-hepatocellular-carcinoma-a-meta-analysis
#12
REVIEW
Manka Zhang, Huimin Ma, Jian Zhang, Lingling He, Xiaohui Ye, Xin Li
BACKGROUND AND AIMS: Hepatic resection (HRN) and microwave ablation (MWA) have significant advantages in treating hepatocellular carcinoma; however, it remains unclear which way produces better outcomes. This meta-analysis of cohort studies compared the treatments in terms of effectiveness and safety. METHODS: Six electronic databases (PubMed, Medline, EMBASE, Web of Science, EBSCO, and The Cochrane Library) were retrieved for studies comparing MWA and HRN. The meta-analysis was conducted based on statement of preferred reporting items for systematic reviews and meta-analyses...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29037259/immuno-thermal-ablations-boosting-the-anticancer-immune-response
#13
REVIEW
Ryan Slovak, Johannes M Ludwig, Scott N Gettinger, Roy S Herbst, Hyun S Kim
The use of immunomodulation to treat malignancies has seen a recent explosion in interest. The therapeutic appeal of these treatments is far reaching, and many new applications continue to evolve. In particular, immune modulating drugs have the potential to enhance the systemic anticancer immune effects induced by locoregional thermal ablation. The immune responses induced by ablation monotherapy are well documented, but independently they tend to be incapable of evoking a robust antitumor response. By adding immunomodulators to traditional ablative techniques, several researchers have sought to amplify the induced immune response and trigger systemic antitumor activity...
October 17, 2017: Journal for Immunotherapy of Cancer
https://www.readbyqxmd.com/read/29031662/percutaneous-treatment-of-hepatocellular-carcinoma-state-of-the-art-and-innovations
#14
REVIEW
Jean-Charles Nault, Olivier Sutter, Pierre Nahon, Nathalie Ganne-Carrié, Olivier Séror
Percutaneous treatment of hepatocellular carcinoma (HCC) encompasses a vast range of techniques, including monopolar radiofrequency ablation (RFA), multibipolar RFA, microwave ablation, cryoablation and irreversible electroporation. RFA is considered to be one of the main curative treatments for HCC of less than 5 cm developing on cirrhosis, together with surgical resection and liver transplantation. However, controversies exist concerning the respective roles of ablation and liver resection for HCC of less than 3 to 5 cm on cirrhosis...
October 12, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/29025295/ultrasonography-guided-percutaneous-microwave-ablation-for-large-hepatic-cavernous-hemangiomas
#15
Fangyi Liu, Xiaoling Yu, Ping Liang, Zhigang Cheng, Zhiyu Han, Jie Yu
PURPOSE: To evaluate the efficacy and safety of ultrasound-guided percutaneous microwave ablation (MWA) for large hepatic cavernous hemangiomas (HCHs) with ablation of the feeding artery and aspiration of blood from hemangioma simultaneously. MATERIALS AND METHODS: From January 2011 to December 2016, 40 patients (29 females, 11male; average age 43.25±7.65 years) with 42 giant hepatic hemangiomas (mean diameter7.02±1.55cm, range4.1-10.8 cm) were treated with image-guided percutaneous MWA with ablation of the feeding artery and aspiration of blood from hemangioma simultaneously...
October 12, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28982246/application-of-microwave-ablation-in-the-emergent-control-of-intraoperative-life-threatening-tumor-hemorrhage-during-hepatic-surgeries
#16
Haoming Zhou, Jindao Wu, Wei Ling, Deming Zhu, Ling Lu, Xuehao Wang, Liyong Pu, Lianbao Kong
PURPOSE: This study was designed to evaluate the efficacy and safety of microwave ablation (MWA) in the treatment of intraoperative life-threatening tumour haemorrhage during hepatic surgeries. METHODS: Three cases of MWA application in the emergent control of life-threatening hepatic tumour haemorrhage were analysed and reported. RESULTS: Satisfactory hemostasis for hepatic tumour rupture was achieved by MWA in all three cases. No major complications, such as post-operative haemorrhage, bile duct injury, liver abscess, colon perforation, skin burns, tumour seeding or renal dysfunction, were identified...
October 23, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28978941/the-influence-of-liposomal-quercetin-on-liver-damage-induced-by-microwave-ablation
#17
Xuhua Duan, Pengfei Chen, Xinwei Han, Jianzhuang Ren, Zhaoyang Wang, Guorui Zhao, Hao Li
This study aimed to observe whether liposomal quercetin (LQ) can enhance the effect of microwave ablation (MWA) on hepatic parenchyma destruction. Forty-eight rabbits were randomly divided into three groups: LQ group, MWA group and LQ + MWA group. Serum and liver samples were collected. The coagulation volume (CV) of hepatic parenchyma, histopathological changes and liver function were compared. Hepatocyte apoptosis was examined through TUNEL. The expression of heat shock protein 70 (HSP70), hypoxia-inducible factor-1α (HIF-1α) and tumor necrosis factor-α (TNF-α) were analyzed...
October 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28969964/localized-microbubble-cavitation-based-antivascular-therapy-for-improving-hcc-treatment-response-to-radiotherapy
#18
Annemarie Daecher, Maria Stanczak, Ji-Bin Liu, Jie Zhang, Shisuo Du, Flemming Forsberg, Dennis B Leeper, John R Eisenbrey
Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality worldwide and the fastest growing malignancy in the United States. With a 5-year survival rate below 12%, effective therapies for HCC are needed. Current treatments for HCC include microwave and radiofrequency ablation, high intensity focused ultrasound, liver transplant, surgical resection, and localized embolizations. However, each of these approaches has some limitation, making it imperative to develop improved methods for sensitizing tumors prior to therapy...
September 29, 2017: Cancer Letters
https://www.readbyqxmd.com/read/28964016/laser-ablated-hydantoin-a-high-resolution-rotational-study
#19
Elena R Alonso, Lucie Kolesniková, José L Alonso
Laser ablation techniques coupled with broadband and narrowband Fourier transform microwave spectroscopies have allowed the high resolution rotational study of solid hydantoin, an important target in astrochemistry as a possible precursor of glycine. The complicated hyperfine structure arising from the presence of two (14)N nuclei in non-equivalent positions has been resolved and interpreted in terms of the nuclear quadrupole coupling interactions. The results reported in this work provide a solid base for the interstellar searches of hydantoin in the astrophysical surveys...
September 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28956645/multimodal-treatment-of-advanced-renal-cancer-in-2017
#20
Alessia Mennitto, Elena Verzoni, Paolo Grassi, Raffaele Ratta, Giovanni Fucà, Giuseppe Procopio
in the last decades, the treatment of renal cell carcinoma has become more complex due to the introduction of novel systemic agents and the improvement of the loco-regional therapies that prolong survival maintaining a good quality of life. Areas covered: in this review, we summarize the currently available local and systemic treatment options, their indications and their hypothetical role in the management of advanced renal cell carcinoma, highlighting the need of multimodality treatment paradigms within interdisciplinary decision-making...
September 28, 2017: Expert Review of Clinical Pharmacology
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