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Mustafa Uyar, Necdet Kuyucu, Seda Tezcan, Gönül Aslan, Bahar Tasdelen
Acute bronchiolitis, mostly seen in infants and younger children, is a lower respiratory tract infection frequently caused by viral agents. We aimed to determine the frequency of a broad panel of respiratory viruses including human bocavirus (HBoV) and to assess the clinical characteristics of acute bronchiolitis in a group of children under 24 months of age. A total of 62 children (45 male, 17 female; age range: 0-2 years) with the initial diagnosis of acute bronchiolitis and 33 healthy children (21 male, 12 female; age range: 0-2 years) as control group who were admitted to the Pediatrics Department of Mersin University Hospital, southern Turkey, from January to July 2010 were included in the study...
April 2014: Mikrobiyoloji Bülteni
Süleyman Yazar, Ozgür Koru, Berna Hamamcı, Ulfet Cetinkaya, Ulkü Karaman, Salih Kuk
All microsporidia are obligate parasites and have no active stages outside their host cells. Microsporidia lack some typical eukaryotic characteristics. There are now over 1200 species identified in 144 genera. The most familiar stage of microsporidia is the small, highly resistant spore, the size of which differs according to the species and is often 1-10 μm. The general life cycle pattern of the microsporidia can be divided into three phases: the infective or environmental phase, the proliferative phase, and the sporogony or spore-forming phase...
2013: Türkiye Parazitolojii Dergisi
Tobias Kamphuis, Tjarko Meijerhof, Toon Stegmann, Julia Lederhofer, Jan Wilschut, Aalzen de Haan
Respiratory Syncytial Virus (RSV) is a major cause of viral brochiolitis in infants and young children and is also a significant problem in elderly and immuno-compromised adults. To date there is no efficacious and safe RSV vaccine, partially because of the outcome of a clinical trial in the 1960s with a formalin-inactivated RSV vaccine (FI-RSV). This vaccine caused enhanced respiratory disease upon exposure to the live virus, leading to increased morbidity and the death of two children. Subsequent analyses of this incident showed that FI-RSV induces a Th2-skewed immune response together with poorly neutralizing antibodies...
2012: PloS One
Tae-Ok Kim, In-Jae Oh, Hyun-Wook Kang, Su-Young Chi, Hee-Jung Ban, Yong-Soo Kwon, Kyu-Sik Kim, Yu-Il Kim, Sung-Chul Lim, Young-Chul Kim
Temozolomide is an oral alkylating agent with clinical activity against glioblastoma multiforme (GM). It is generally well-tolerated and has few pulmonary side effects. We report a case of temozolomide-associated brochiolitis obliterans organizing pneumonia (BOOP) requiring very high-dose corticosteroid treatment. A 56-yr-old woman presented with a 2-week history of exertional dyspnea. For the treatment of GM diagnosed 4 months previously, she had undergone surgery followed by chemoradiotherapy, and then planned adjuvant chemotherapy with temozolomide...
April 2012: Journal of Korean Medical Science
Devendra Desai, Samir Patil, Zarir Udwadia, Shailendra Maheshwari, Philip Abraham, Anand Joshi
BACKGROUND: Although pulmonary abnormalities have been recognized in patients with inflammatory bowel diseases (IBD), their prevalence and clinical significance are not known. AIM: To study the prevalence and clinical significance of pulmonary abnormalities in patients with IBD. METHODS: Ninety-five non-consecutive patients with IBD (12 Crohn's disease, 83 ulcerative colitis; mean age 41.9 [SD 13] years; 47 women) were prospectively studied from January 2007 to March 2010...
September 2011: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Yi-Hong Liu, Li-Ping Xiong, Hong-Yuan Shen
OBJECTIVE: To study the changes of red cell immune function and T-lymphocyte subsets in children with bronchiolitis and their possible roles in the pathogenesis of bronchiolitis. METHODS: Forty-five children with bronchiolitis and 30 healthy controls were enrolled. Red cell immune complex rosette (RBC-ICR) and red cell C3b receptor rosette (RBC-C3bRR) were detected. The percentages of CD3+, CD4+ and CD8+ cells were assayed by flow cytometry. RESULTS: RBC-C3bRR[(13...
March 2011: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
Cristina T L Dornelles, Jefferson P Piva, Paulo J C Marostica
Acute viral bronchiolitis is a common respiratory infectious disease of infancy. A prospective study was carried out with 175 infants aged up to six months to evaluate their nutritional and breastfeeding status as possible risk factors for unfavourable evolution of previously-healthy infants from a care hospital. Immunofluorescence test for virus and anthropometric assessment were performed. Outcomes were length of oxygen-use, length of hospital stay, and type of hospital unit needed. Seventy-three percent of the infants were well-nourished, 6% undernourished, 8...
September 2007: Journal of Health, Population, and Nutrition
Mohammed A Al-Shehri, Ali Sadeq, Kazim Quli
BACKGROUND: Bronchiolitis is the most common lower respiratory tract infection in children less than 24 months of age and the most frequent cause of hospitalization in infants under 6 months of age. OBJECTIVES: To determine the viral etiology and predictors for hospital admission of children with bronchiolitis in Abha city, southwest Saudi Arabia. METHODS AND MATERIALS: Children five years old or younger diagnosed with bronchiolitis were enrolled in the study as a study-group of admitted cases (n=51) and a control-group of non-admitted cases (n=115)...
October 2005: West African Journal of Medicine
Debora Ingrid Sohn, Hugo Armando Laborde, Marta Bellotti, Luis Seijo
Diverse pleuropulmonary manifestations, including pleural effusion, rheumatoid nodulosis, fibrosis, obliterans brochiolitis, bronchiectasias, vasculitis, drug-induced lung disease, and obliterans bronchiolitis with organized pneumonia, have been described in patients with rheumatoid arthritis (RA). Bronchiolitis obliterans organized pneumonia (BOOP) is an uncommon condition described in patients with RA but not in juvenile RA (JRA). We described a patient with JRA who developed a BOOP.
February 2007: Clinical Rheumatology
Fernando Perez-Zincer, Jaya V Juturi, Eric D Hsi, Gerald A Hoeltge, Lisa A Rybicki, Matt E Kalaycio
Different subtypes of acute myelogenous leukemia have distinct clinical presentations and courses. The specific clinical and molecular aspects of these leukemias have helped modify and create specific strategies for their management. We observed an increased incidence of pulmonary complications in patients with acute myelomonocytic leukemias (AMML) with inversion of chromosome 16 [inv(16)] irrespective of the presence of hyperleukocytosis. We reviewed patient records available over a period of 12 years at The Cleveland Clinic Foundation of patients with AMML with inv(16) and compared the incidence of pulmonary complications to a matched control group of patients with AMML but without inv(16)...
January 2003: Leukemia & Lymphoma
Hubert De Crémoux
The majority of bronchial and interstitial diseases of the adult are accompanied by bronchiolar inflammation, but over time the use of the term "bronchiolitis" has been limited to a few specific affections. Bronchiolitis with predominantly alveolar involvement Some "bronchiolites" emphasize the problem of an interstitial pneumopathy, since the disease predominantly involves the alveolar spaces. Only a few bronchiolites are severely damaging: bronchiolitis obliterans with organizing pneumonia and interstitial pneumopathy with respiratory bronchiolitis...
February 22, 2003: La Presse Médicale
Kihyun Kim, Mark H Lee, Jingook Kim, Kyung Soo Lee, Sung Min Kim, Man Pyo Jung, Joungho Han, Ki Woong Sung, Won Seog Kim, Chul Won Jung, Sung Soo Yoon, Young-Hyuck Im, Won Ki Kang, Keunchil Park, Chan Hyung Park
Invasive pulmonary aspergillosis is a serious infectious complication in immunocompromised patients. Recent reports indicate its favorable clinical outcomes by early diagnosis with chest computed tomography scan. We retrospectively analyzed our experiences with histopathological evaluation by open lung biopsy in 31 patients (32 cases) with hematologic malignancies, suspected of having invasive pulmonary aspergillosis clinically and radiologically. Although the initial computed tomography findings of all cases were highly indicative of invasive pulmonary aspergillosis by demonstrating nodules or masses with a halo sign (16 cases), segmental area of consolidation with ground-glass attenuation (7 cases), both nodules or masses with a halo sign and segmental area of consolidation with ground-glass attenuation (7 cases) and poorly defined centrilobular nodules (2 cases), we could histopathologically confirm invasive fungal infections only in 17 cases (53...
October 2002: American Journal of Hematology
J C Dunn, K W West, F J Rescorla, L R Tres Scherer, S A Engum, T M Rouse, J W Smith, J L Grosfeld
BACKGROUND/PURPOSE: Pulmonary infiltrates in recipients of stem cell transplantation often present as diagnostic dilemmas. Although lung biopsy may establish the diagnosis of parenchymal disease, it remains unclear whether such a procedure results in a significant change in the patient's treatment and outcome. This study evaluates the efficacy of lung biopsy in recipients of stem cell transplantation. METHODS: The medical records of 15 stem cell transplant recipients who underwent 18 lung biopsies were reviewed...
August 2001: Journal of Pediatric Surgery
F Macori, V Iacari, M Falchetto Osti, G Potente, G Anaveri
INTRODUCTION: High Resolution Computed Tomography (HRCT) has been used by many authors to study the early complications of lung transplantation. Bronchoscopy, transbronchial biopsy and the clinical parameters are the tools of choice to diagnose such complications; HRCT showed excellent sensitivity (100%) and good specificity (93%) especially in detecting bronchial stenoses. We report the preliminary results of HRCT in detecting early/late complications in lung transplant recipients. MATERIAL AND METHODS: Sixteen lung transplant recipients (5 single and 11 double transplants) were examined with HRCT at the Servizio Speciale Diagnostica V of "La Sapienza" University (Rome, Italy)...
July 1998: La Radiologia Medica
M Raes, V Peeters, P Alliet, P Gillis, J Kortleven, K Magerman, J L Rummens
Most data concerning immunopathogenetic mechanisms involved in respiratory syncytial virus (RSV) infection are derived from animal studies. In infants with RSV bronchiolitis the target organ i.e. the airway is hard to explore. We looked for specific alterations in peripheral blood lymphocyte subpopulations in infants hospitalized for RSV bronchiolitis. Flow cytometric analysis with a large panel of monoclonals was performed on peripheral blood lymphocytes in thirty-two infants (mean age: 4.9 months) admitted for RSV bronchiolitis...
May 1997: Pediatric Allergy and Immunology
K al-Kattan, S Tadjkarimi, A Cox, N Banner, A Khaghani, M Yacoub
BACKGROUND: Heart and lung transplantation used to be the standard operation for patients with emphysema. Because of the shortage of donors, more patients are having single lung transplantation with satisfactory short-term results. METHODS: This study was performed to evaluate the long-term results of both groups. During the period between December 1985 and December 1993, 89 patients underwent lung transplantation, and 68 patients (43 male and 25 female) underwent single lung transplantation...
September 1995: Journal of Heart and Lung Transplantation
S Rajjoub, M W Blatt, J Ritterspach
Lymphangioleiomyomatosis (LAM) is defined as an abnormal proliferation of smooth muscles around lymphatics, venules, and brochioles. This article describes our experiences treating a 21-year-old, white female who experienced recurrent shortness of breath during air travel last year. Her episode was severe and the patient was transported to the hospital as soon as the airplane landed. Physical exam in the emergency room was significant for absent breath sounds on the right side and the chest X-ray revealed a pneumothorax...
November 1995: West Virginia Medical Journal
H Spencer, D H Dail, J Arneaud
Nineteen papillary, non-invasive tumors arising from the bronchial epithelium but excluding carcinoid tumors are reviewed. Eight were solitary papillomas of which three were covered with a mixture of epithelial types. Seven were benign but one had a focus of carcinoma in situ. A similar change was seen in bronchial epithelium adjacent to a papilloma. Two cases of recurrent papillomas were seen and in one, carcinomatous changes eventually occurred. Two combined benign brochial cystadenomas with papillomas are described...
March 15, 1980: Cancer
Y Yagi, T Saku, M Hatae, S Yagi, H Fujisaki, T Shimotsu
Immunoperoxidase staining for human keratin proteins (hKP) was performed cytochemically in samples from 79 cancer patients, and histochemically in samples from 134 cancer patients. Immunohistochemically, hKP was present in almost all patients with squamous cell carcinoma (lung), transitional cell carcinoma (urinary bladder), adenocarcinoma (lung, stomach, breast, ovary), bronchiole-alveolar carcinoma (lung), and large cell carcinoma (lung). It was detected in 40% of the patients with small cell carcinoma (lung)...
September 1984: Gan No Rinsho. Japan Journal of Cancer Clinics
T L Petty, G W Silvers, R E Stanford
Thirty-nine excised human lungs were examined to identify early changes in the small airways, their size distribution, and their elastic recoil in relation to mild degrees of emphysema. Elastic recoil measurement, single-breath nitrogen (SBN2) tests, and FEV1 were obtained from 18 lungs with no emphysema and 21 emphysematous lungs with no greater than Grade 5 emphysema score. The mean number of alveolar attachments per brochiole was determined from all the bronchioles cut in cross section. When the 2 groups of lungs were compared, the percentage of predicted elastic recoil of the nonemphysematous lungs was significantly greater at 50, 70, 80, and 90% of TLC than in the mildly emphysematous lungs...
October 1987: American Review of Respiratory Disease
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