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Spinal dysraphism

Justin J Finch, Chase W Kwon, Hanspaul S Makkar
No abstract text is available yet for this article.
March 14, 2018: JAMA Dermatology
Maria Oliveira, James Fraser McConnell, Thomas W Maddox, Daniel Sanchez-Masian, Rita Gonçalves
The constructive interference in steady state (CISS) sequence has been widely used in human neuroimaging. It has been shown to be advantageous in the evaluation of intra-axial and extra-axial cystic abnormalities, arteriovenous and dysraphic malformations and disturbances of cerebrospinal fluid circulation. To assess the utility of this technique in small animals, interpretations based on this sequence were compared with those based on T2-weighted (T2W) sequences in 145 dogs that underwent MRI of the spine for suspected spinal cord disease...
March 14, 2018: Veterinary Record
Juliette Hascoet, Benoit Peyronnet, Véronique Forin, Maximilien Baron, Grégoire Capon, Thomas Prudhomme, Clément Allenet, Simon Tournier, Charlotte Maurin, Jean-Nicolas Cornu, Ourdia Bouali, Matthieu Peycelon, Alexis Arnaud, Mariette Renaux-Petel, Agnès Liard, Gilles Karsenty, Andrea Manunta, Xavier Game
OBJECTIVE: To assess the effectiveness of Intradetrusor injections of botulinum toxin type A (IDBTX-A) in children with spina bifida. PATIENTS AND METHODS: All patients aged under 16 year-old who underwent IDBTX-A between 2002 and 2016 at six institutions were included in a retrospective study. Our primary endpoint was the success rate of IDBTX-A defined as both clinical improvement (no incontinence episodes between clean-intermittent catheterization (CIC), absence of urgency, less than 8 CIC per day)) and urodynamic improvement (resolution of derusor overactivity, normal bladder compliance for age) lasting ≥ 12 weeks...
March 6, 2018: Urology
Ying Zhang, Jingming Xie, Yingsong Wang, Ni Bi, Tao Li, Jie Zhang, Zhi Zhao, Hua Ou, Siyuan Liu
PURPOSE: Documents indicated that the average prevalence of intraspinal neural axis abnormalities (INAAs) in presumed idiopathic scoliosis (PIS) patients was about 17.7%. However, paucity study focuses on the incidence of INAAs in severe spinal deformity (SSDs). In this study, we investigate the incidence of intraspinal neural axis abnormalities (IINAAs) and the clinical relevance in SSD at a single center. METHODS: All the patients with SSDs admitted for spinal surgery were evaluated from 2003 to 2014...
February 14, 2018: European Spine Journal
Moon Hyung You, Dong Hoon Shin, Jong Soo Choi, Byeong Su Kim, Yeonwoong Kim, JoonGoon Kim
Fibrous hamartoma of infancy (FHI) is a rare entity with a benign nature. The typical clinical features are a single, slowly growing, painless mass on the trunk that appears within the first 2 years of life. We report a 13-month-old boy who presented with a plaque on the lower back since 4 months of age. The plaque had gradually become larger and firm, and hyperhidrosis and hypertrichosis were noticed. No visible connection between the spinal cord and the lesion was found in radiologic studies, indicating a disease other than spinal dysraphism...
February 26, 2018: Journal of Korean Medical Science
Necmettin Tutuncu, Goktekin Tenekeci, Sakir Unal, Necat Yilmaz, Celal Bagdatoglu
AIM: Whether the macular lesions associated with spinal dysraphism should be preserved is controversial. This area is usually excised during reconstruction. This study aims to characterize the macular lesions associated with spinal dysraphism and to determine the outcomes of cases in which macular lesions are not excised. MATERIAL AND METHODS: The patient cohort comprised 17 patients with spinal dysraphism who were treated at Mersin University Hospital from 2005 through 2007...
December 17, 2017: Turkish Neurosurgery
Ullas V Acharya, Hima Pendharkar, Dandu R Varma, Nupur Pruthi, Shriram Varadarajan
Spinal cord development occurs through three consecutive periods of gastrulation, primary nerulation and secondary neurulation. Aberration in these stages causes abnormalities of the spine and spinal cord, collectively referred as spinal dysraphism. They can be broadly classified as anomalies of gastrulation (disorders of notochord formation and of integration); anomalies of primary neurulation (premature dysjunction and nondysjunction); combined anomalies of gastrulation and primary neurulation and anomalies of secondary neurulation...
October 2017: Indian Journal of Radiology & Imaging
Nicolas Mottet, Yann Chaussy, Frederic Auber, Fabien Guimiot, Francine Arbez-Gindre, Didier Riethmuller, Célia Cretolle, Alexandra Benachi
The estimated prevalence of fetal caudal dysgenesis is 1 per 100,000 births. The functional prognosis of sacral agenesis is dominated by the large spectrum of associated caudal malformations. Except for cases associated with hydrocephalus secondary to open spinal dysraphism or chromosomal anomalies, association with mental deficiency is rare. We propose a systematic prenatal approach to cases of fetal sacral agenesis based on 9 etiologic items: clinical context, type of sacral dysgenesis, associated spinal cord malformations, mobility of lower limbs, investigation of the presacral region, analysis of the gastrointestinal tract, analysis of the genitourinary tract, associated vertebral defects, and cytogenetic analysis...
January 27, 2018: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
Douglas A Canning
No abstract text is available yet for this article.
August 2017: Journal of Urology
Eralp Çevikkalp, Koray Erbüyün, Serpil Erbüyün, Gülay Ok
Pediatric regional anesthesia is widely used to relieve postoperative pain after abdominal surgery. Commonly used techniques of regional anesthesia include lumbar epidural and caudal block. However, the use of central neuraxial blockade has limitations. It is contraindicated in patients with clotting abnormalities, spinal dysraphism with tethered cord syndrome, meningomyelocele, and following spinal surgery with instrumentation. Ultrasound guided transversus abdominis plane block is a new method of regional anesthesia that can be used in settings where central neuraxial blockade is contraindicated...
January 2018: Saudi Medical Journal
Sofia Kamakh Asaad, Anne-Sofie Caroline Jensen, Carsten Reidies Bjarkam
No abstract text is available yet for this article.
January 9, 2018: British Journal of Neurosurgery
Ankush Gupta, Vedantam Rajshekhar
PURPOSE: The purpose of this study was to assess the prevalence of FFT as an additional tethering element in children operated for closed spinal dysraphism, where FFT was not the primary tethering pathology. METHODS: This is a retrospective study of 195 children (< 18 years of age) who underwent surgery for closed spinal dysraphism and did not have FFT as the primary diagnosis. All patients were operated during the period 2005-2017 by a single surgeon. The commonest diagnosis was a lipomyelomeningocele (LMMC, n = 81, 41...
December 19, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Civan Islak, Sedat Giray Kandemirli, Osman Kizilkilic, Naci Kocer, Saffet Tuzgen, Mehmet Murat Hanci
BACKGROUND: Spinal vascular malformations as a group are rare, and coexistence of a spinal arteriovenous malformation (AVM) in or around the spinal dysraphism is extremely rare. We report 2 cases of combined spinal dysraphism and vascular malformations of the spinal cord. CASE DESCRIPTION: The first case was an AVM located in a filum terminale lipoma fed by the artery of the filum terminale. This case was managed by multiple endovascular embolizations followed by surgery...
February 2018: World Neurosurgery
Aaron Mohanty
No abstract text is available yet for this article.
October 2017: Journal of Neurosciences in Rural Practice
Rocco Severino, Paolo Severino
Background: Intramedullary, nondysraphic, spinal cord lipomas are rare and account for less than 1% of all spinal cord lesions. Symptoms typically consist of a progressive myelopathy associated with increasing degrees of paralysis (e.g., quadriparesis/plegia, paraparesis/plegia). Case Description: A 39-year-old male, without a history of spinal dysraphism, presented with a progressive spastic quadriparesis. This was attributed to magnetic resonance-documented large intramedullary cervical lipoma...
2017: Surgical Neurology International
Matthew D Timberlake, Adam J Kern, Richard Adams, Candice Walker, Bruce J Schlomer, Micah A Jacobs
PURPOSE: Report urologic outcomes among newborns with spinal dysraphism managed within an expectant clean intermittent catheterization (CIC) program. METHODS: Newborns were followed clinically and with serial ultrasound (US). Urodynamics (UD) and dimercaptosuccinic acid (DMSA) renal scan were obtained at 3-6 months, 1 year, 3 years, then as needed. Patients with initial evaluation after 6 months were excluded. RESULTS: Median follow-up was 3...
October 20, 2017: Journal of Pediatric Rehabilitation Medicine
Nobuya Murakami, Takato Morioka, Takafumi Shimogawa, Kimiaki Hashiguchi, Nobutaka Mukae, Kazuyoshi Uchihashi, Satoshi O Suzuki, Koji Iihara
BACKGROUND: A retained medullary cord (RMC) is a rare closed spinal dysraphism with a robust elongated neural structure continuous from the conus and extending to the dural cul-de-sac. One case extending down to the base of a subcutaneous meningocele at the sacral level has been reported. CLINICAL PRESENTATION: We report on three cases of closed spinal dysraphism, in which a spinal cord-like tethering structure extended out from the dural cul-de-sac and terminated at a skin-covered meningocele sac in the sacrococcygeal region, which was well delineated in curvilinear coronal reconstructed images of 3D-heavily T2-weighted images (3D-hT2WI)...
November 3, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
E Ausili, G Maresca, L Massimi, L Morgante, C Romagnoli, C Rendeli
PURPOSE: The purpose of this paper is to investigate occult spinal dysraphisms (OSD) using lumbar ultrasonography (LUS) in newborns presenting with specific skin markers or sacrococcygeal dimple. METHOD: From 2012 to 2015, we performed LUS in newborns with cutaneous stigmata and/or sacroccygeal dimple. Magnetic resonance imaging (MRI) was performed in all patients with abnormal ultrasound or features of neurological involvement in order to detect spinal lesions...
October 27, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Zine-Eddine Khene, Fanny Paret, Marie-Aime E Perrouin-Verbe, Thomas Prudhomme, Juliette Hascoet, Mathilde Nedelec, Jacques Kerdraon, Helene Menard, Magali Jezequel, Loïc Le Normand, Andrea Manunta, Xavier Game, Benoit Peyronnet
PURPOSE: To evaluate the perioperative and long-term functional outcomes of bladder neck and peribulbar cuff placement of an artificial urinary sphincter (AUS) in a population of adult male patients with spinal dysraphism. PATIENTS AND METHODS: A retrospective analysis of the French spina bifida (SB) network database was performed. Patients who underwent implantation of an AUS from January 1985 to November 2015 were selected and stratified into two groups according to cuff location: bladder neck vs...
October 13, 2017: Journal of Urology
Sujeet Kumar Meher, Laxmi Narayan Tripathy, Harsh Jain, Sunandan Basu
Spinal cord lipomas are usually associated with spinal dysraphism and is most common in lumbosacral region. Spinal intradural lipoma is a rare condition accounting for less than 1% of spinal cord tumours and is most prevalent in cervicodorsal region. Intramedullary spinal cord lipoma of cervical spine not associated with spinal dysraphism is one of the rarest lesions. They usually present insidiously with slowly progressive myelopathic deficits. We present a case of nondysraphic intramedullary spinal cord lipoma with exophytic component and intracranial extension...
July 2017: Journal of Craniovertebral Junction and Spine
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