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https://www.readbyqxmd.com/read/28888911/photobiomodulation-with-670%C3%A2-nm-light-ameliorates-m%C3%A3-ller-cell-mediated-activation-of-microglia-and-macrophages-in-retinal-degeneration
#1
Yen-Zhen Lu, Riccardo Natoli, Michele Madigan, Nilisha Fernando, Kartik Saxena, Riemke Aggio-Bruce, Haihan Jiao, Jan Provis, Krisztina Valter
Müller cells, the supporting cells of the retina, play a key role in responding to retinal stress by releasing chemokines, including CCL2, to recruit microglia and macrophages (MG/MΦ) into the damaged retina. Photobiomodulation (PBM) with 670 nm light has been shown to reduce inflammation in models of retinal degeneration. In this study, we aimed to investigate whether 670 nm light had an effect on Müller cell-initiated inflammation under retinal photo-oxidative damage (PD) in vivo and in vitro. Sprague-Dawley rats were pre-treated with 670 nm light (9J/cm(2)) once daily over 5 days prior to PD...
September 6, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28871567/a-case-of-biliary-atresia-with-pancreaticobiliary-maljunction
#2
Kosuke Endo, Akiko Yokoi, Yasuhiko Mishima, Akihiko Tamaki, Keiichi Morita, Yuichi Okata, Chieko Hisamatsu, Hiroaki Fukuzawa, Makiko Yoshida, Yoshinobu Akasaka, Kosaku Maeda
BACKGROUND: The pathogenesis of biliary atresia (BA) is still unknown. There are several reports on the etiology of BA, including pancreaticobiliary maljunction (PBM). We experienced a case of Kasai type IIIa BA with PBM, in which we found elevation of pancreatic enzymes in the gallbladder. We evaluated whether PBM is related to the pathogenesis of BA based on our findings. CASE PRESENTATION: The patient was born at 40 weeks of gestation. His body weight at birth was 2850 g...
September 5, 2017: Surgical Case Reports
https://www.readbyqxmd.com/read/28867926/quantum-dot-light-emitting-devices-for-photomedical-applications
#3
Hao Chen, Juan He, Raymond Lanzafame, Istvan Stadler, Hamid El Hamidi, Hui Liu, Jonathan Celli, Michael R Hamblin, Yingying Huang, Emily Oakley, Gal Shafirstein, Ho-Kyoon Chung, Shin-Tson Wu, Yajie Dong
While OLEDs have struggled to find a niche lighting application that can fully take advantage of their unique form factors as thin, flexible, lightweight and uniformly large-area luminaire, photomedical researchers have been in search of low-cost, effective illumination devices with such form factors that could facilitate widespread clinical applications of photodynamic therapy (PDT) or photobiomodulation (PBM). Although existing OLEDs with either fluorescent or phosphorescent emitters cannot achieve the required high power density at the right wavelength windows for photomedicine, the recently developed ultrabright and efficient deep red quantum dot light emitting devices (QLEDs) can nicely fit into this niche...
March 2017: Journal of the Society for Information Display
https://www.readbyqxmd.com/read/28846932/effect-of-in-vivo-low-level-laser-therapy-on-bone-marrow-derived-mesenchymal-stem-cells-in-ovariectomy-induced-osteoporosis-of-rats
#4
Ataroalsadat Mostafavinia, Leila Dehdehi, Seyed Kamran Ghoreishi, Behnam Hajihossainlou, Mohammad Bayat
Postmenopausal osteoporosis (PMOP) is considered by decreased bone strength that escalates the threat of fractures. Positive effects of photobiomodulation (PBM) with pulse wave have been demonstrated in cell culture and animal models. The aim of this study was to assess the in vivo effects of PBM on viability and calcium ion release of ovariectomy induced osteoporosis (OVX) - bone marrow derived mesenchymal stem cells (BMMSCs). MATERIAL AND METHODS: 18 female rats were distributed into the following groups: 1) control healthy, 2) LASER-healthy (890nm, 80Hz, 1...
August 18, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28840382/new-photobiomodulation-protocol-prevents-oral-mucositis-in-hematopoietic-stem-cell-transplantation-recipients-a-retrospective-study
#5
Camila Weissheimer, Marina Curra, Lauro J Gregianin, Liane E Daudt, Vivian P Wagner, Marco Antonio T Martins, Manoela D Martins
Oral mucositis (OM) is an adverse side effect among hematopoietic stem cell transplantation (HSCT) recipients. The objective of this retrospective study was to evaluate the preventive effect of photobiomodulation (PBM) applied three times per week versus seven times per week in patients undergoing HSCT. The risk factors related to the incidence and severity of OM were also assessed. This was a retrospective study that evaluated 99 HSCT recipients who received different PBM protocols. Group I received three sessions per week, and group II received daily treatment...
August 24, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28801810/effects-of-pbm-in-different-energy-densities-and-irradiance-on-maintaining-cell-viability-and-proliferation-of-pulp-fibroblasts-from-human-primary-teeth
#6
Nádia Carolina Teixeira Marques, Natalino Lourenço Neto, Mariel Tavares Oliveira Prado, Luciana Lourenço Ribeiro Vitor, Rodrigo Cardoso Oliveira, Vivien Thiemy Sakai, Carlos Ferreira Santos, Maria Aparecida Andrade Moreira Machado, Thais Marchini Oliveira
This study aimed to compare the effects of photobiomodulation (PBM) in different energy densities and irradiances on maintaining cell viability, and proliferation of pulp fibroblasts from human primary teeth (HPF) were cultured in DMEM and used between the fourth and eighth passages. Then, HPF were irradiated with the following different energy densities: 1.25 J/cm(2) (a), 2.50 J/cm(2) (b), 3.75 J/cm(2) (c), 5.00 J/cm(2) (d), and 6.25 J/cm(2) (e); but varying either the time of irradiation (groups 1a-1e) or the output power (groups 2a-2e)...
August 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28793884/therapeutic-comparison-between-treatments-for-vulvar-lichen-sclerosus-study-protocol-of-a-randomized-prospective-and-controlled-trial
#7
Renata A Belotto, Maria Cristina Chavantes, João Paulo Tardivo, Roberto Euzébio Dos Santos, Raquel Civolani Marques Fernandes, Anna Carolina Ratto Tempestini Horliana, Christiane Pavani, Daniela Fátima Teixeira da Silva
BACKGROUND: Vulvar lichen sclerosus (VLS) is a lymphocyte-mediated disease of unknown etiology that can cause intense itching as well stenosis, hindering the evacuation and urination. It can also limit the sex life due to severe local pruritus, pain and dyspareunia (pain during sexual intercourse). The standard treatment for this disease is the use of topical corticosteroids to reduce the clinical symptoms and to try to increase disease-free intervals. Photodynamic therapy (PDT), a treatment that associates a light radiation with a photosensitizing agent and photobiomodulation (PBM) are therapies that can promote effective immunomodulatory responses at the application site by means of photophysical and photochemical phenomena from the molecular to the systemic level, which promote their use in chronic dermatoses...
August 10, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28782883/gallbladder-mucosal-lesions-associated-with-high-biliary-amylase-irrespective-of-pancreaticobiliary-maljunction
#8
Jason Free, Frank Wang, Nick Williams, Justin S Gundara, Ralph F Staerkle, Thomas J Hugh, Jaswinder S Samra
BACKGROUND: Previous studies have focused on the presence of reflux in selected cohorts with pancreaticobiliary maljunction (PBM), but little is known regarding the wider incidence of occult reflux and associated mucosal changes. We aimed to correlate gallbladder mucosal abnormalities with objective evidence of PBM and occult pancreaticobiliary reflux (PBR) in an Australian population undergoing cholecystectomy. METHODS: Patients undergoing cholecystectomy between September 2010 and September 2012 were eligible for inclusion...
August 7, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28776111/methylene-blue-mediated-photobiomodulation-on-human-osteoblast-cells
#9
Gamze Bölükbaşı Ateş, Ayşe Ak, Bora Garipcan, Murat Gülsoy
Photobiomodulation (PBM) and photodynamic therapy (PDT) are two major methods, which use light in medicine and dentistry. PBM uses low-level laser light to induce cell proliferation and activity. In contrast, PDT use laser light combined with a photosensitizer (PS) to cause cell death. Due to similar, not fully understood mechanisms and biphasic response of light, unexpected and complex outcomes may be observed. In the present study, the effect of 635 nm laser light, with power density 50 mW/cm(2), at three different energy densities (0...
August 4, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28773005/implant-stability-of-biological-hydroxyapatites-used-in-dentistry
#10
Maria Piedad Ramírez Fernández, Sergio A Gehrke, Patricia Mazón, Jose L Calvo-Guirado, Piedad N De Aza
The aim of the present study was to monitor implant stability after sinus floor elevation with two biomaterials during the first six months of healing by resonance frequency analysis (RFA), and how physico-chemical properties affect the implant stability quotient (ISQ) at the placement and healing sites. Bilateral maxillary sinus augmentation was performed in 10 patients in a split-mouth design using a bobine HA (BBM) as a control and porcine HA (PBM). Six months after sinus lifting, 60 implants were placed in the posterior maxilla...
June 12, 2017: Materials
https://www.readbyqxmd.com/read/28756937/short-pulse-neodymium-yttrium-aluminium-garnet-nd-yag-1064nm-laser-irradiation-photobiomodulates-mitochondria-activity-and-cellular-multiplication-of-paramecium-primaurelia-protozoa
#11
Andrea Amaroli, Alberico Benedicenti, Silvia Ravera, Steven Parker, Wayne Selting, Isabella Panfoli, Stefano Benedicenti
Few studies exist to explore the potential photobiomodulation (PBM) effect of neodymium:yttrium-aluminium garnet (Nd:YAG) laser irradiation using a flat-top handpiece delivery system. In this study, we explored the photobiomodulation effect of that laser, on Paramecium primaurelia. The parameters for the different study groups were: 0.50W, 10Hz, 100msp, 30J/cm(2); 0.75W, 10Hz, 100msp, 45J/cm(2); 1.00W, 10Hz, 100msp, 60J/cm(2); 1.25W, 10Hz, 100msp, 75J/cm(2) and 1.50W, 10Hz, 100msp, 90J/cm(2). Our results suggest that only the parameter 0...
June 19, 2017: European Journal of Protistology
https://www.readbyqxmd.com/read/28748217/mechanisms-and-applications-of-the-anti-inflammatory-effects-of-photobiomodulation
#12
Michael R Hamblin
Photobiomodulation (PBM) also known as low-level level laser therapy is the use of red and near-infrared light to stimulate healing, relieve pain, and reduce inflammation. The primary chromophores have been identified as cytochrome c oxidase in mitochondria, and calcium ion channels (possibly mediated by light absorption by opsins). Secondary effects of photon absorption include increases in ATP, a brief burst of reactive oxygen species, an increase in nitric oxide, and modulation of calcium levels. Tertiary effects include activation of a wide range of transcription factors leading to improved cell survival, increased proliferation and migration, and new protein synthesis...
2017: AIMS Biophysics
https://www.readbyqxmd.com/read/28742438/effect-of-low-level-laser-therapy-on-bone-regeneration-during-osseointegration-and-bone-graft
#13
Randa Zein, Wayne Selting, Stefano Benedicenti
BACKGROUND: The effect of low-level laser therapy (LLLT) on bone regeneration during osseointegration and bone graft is very controversial. Despite many positive reports of in vitro and in vivo studies and more than 50 randomized clinical trials claiming a positive effect of photobiomodulation (PBM), many reports found no significant effect of lasers. OBJECTIVE: The aim of this study was to evaluate studies correlating PBM and bone regeneration and to assesses parameters that produce positive results based on dose and output power used...
July 21, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28736641/bone-marrow-tolerance-during-postoperative-chemotherapy-in-colorectal-carcinomas
#14
Neil B Newman, Rebecca A Moss, Nell Maloney-Patel, Kristen Donohue, Teresa V Brown, Michael J Nissenblatt, Shou-En Lu, Salma K Jabbour
BACKGROUND: This study seeks to quantify and compare bone marrow tolerance during postoperative chemotherapy therapy between rectal cancer vs. colon cancer patients. During rectal cancer treatment, patients receive neoadjuvant chemoradiation (CRT) irradiation which can exacerbate the hematologic toxicity (HT) via incidental irradiation of the pelvic bone marrow (PBM) during myelosuppressive postoperative chemotherapy. In contrast, colon cancer patients receive the same postoperative myelosuppressive chemotherapy but do not routinely receive preoperative chemoradiation therapy...
June 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28725994/evaluation-of-the-effects-of-photobiomodulation-on-vertebras-in-two-rat-models-of-experimental-osteoporosis
#15
Mohammadjavad Fredoni, Mahdi Ghatrehsamani, Mohammad-Amin Abdollahifar, Sahar Bayat, Mohammad Bayat
The aim of this study was to evaluate the effects of photobiomodulation (PBM) on cancellous bone in rat models of ovariectomized induced osteoporosis (OVX-D) and glucocorticoid-induced osteoporosis (GIOP). The experiment comprised of nine groups. A group of healthy rats was used for baseline evaluations. The OVX-D rats were further divided into groups as follows: control rats with osteoporosis, OVX-D rats that received alendronate (1 mg/kg 60 days), OVX-D rats treated with pulsed wave laser (890 nm, 80 Hz, 900 s, 0...
July 19, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28702983/photobiomodulation-in-the-treatment-of-chronic-non-responding-wounds
#16
S E Aragona, G Mereghetti, G Gianazza, E Equizi, J Lotti, T Lotti, C Battioli
We present a protocol of care and therapeutic approach to skin lesions, called AIMED (Anti Inflammatory Regenerative Medicine), which is based on the circularity of its phases and applied therapeutic methodologies. We used photobiomodulation (PBM) for the examination non-responding skin lesions. PBM is an adjuvant treatment for the stimulation of regenerative cellular processes, reduction of inflammation and pain and biochemical modulation of molecular response. We used PBM for the examination of skin lesions, which were not responding to other therapies...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28698130/enzymatic-hydrolysis-of-poly-ethyleneterephthalate-used-for-and-analysed-by-pore-modification-of-track-etched-membranes
#17
Caroline Gamerith, Martyna Gajda, Andreas Ortner, Enrique Herrero Acero, Georg M Guebitz, Mathias Ulbricht
The potential of limited enzymatic poly(ethylene terephthalate) (PET) surface hydrolysis for the modification of track-etched (TE) membranes was investigated. Cutinases 1 and 2 from Thermobifida cellulosilytica as well as a fusion protein of cutinase 1 with the polymer binding module from the polyhydroxyalkanoate depolymerase of Alcaligenes faecalis (Thc_Cut1_PBM) were shown to hydrolyse highly crystalline PET TE membranes with a pore diameter of ∼120nm at very narrow size distribution. Furthermore the effects of surface chemistry were investigated by comparison of enzymatic hydrolysis by Thc_Cut1_PBM of "as received" PET TE membranes with two surface functionalized versions towards a "hydrophilic" and a more "hydrophobic" surface...
July 8, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28674791/effects-of-the-gaalas-diode-laser-780%C3%A2-nm-on-the-periodontal-tissues-during-orthodontic-tooth-movement-in-diabetes-rats-histomorphological-and-immunohistochemical-analysis
#18
Mônica Fernandes Gomes, Maria da Graças Vilela Goulart, Lilian Chrystiane Giannasi, Cybelle Mori Hiraoka, Gabriela de Fátima Santana Melo, Aretha Graziela Vilela de Sousa, Celestino José Prudente Nóbrega, Renato Amaro Zangaro, Miguel Angel Castillo Salgado
The purposes of the present study are to assess the effects of the GaAlAs diode laser on the periodontal tissues and to investigate its action on the alveolar bone remodeling process during orthodontic tooth movement in normoglycemic and diabetic rats. Sixty adult male Wistar rats were divided into four groups of 15 rats: normoglycemic (N), diabetic (D), laser-normoglycemic (LN), and laser-diabetic (LD) rats. Diabetes mellitus was induced by a single intravenous injection of 40 mg/kg monohydrated alloxan. The orthodontically moved tooth underwent a force magnitude of 20 cN...
July 3, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28671296/blood-use-in-patients-receiving-intensive-chemotherapy-for-acute-leukemia-or-hematopoietic-stem-cell-transplantation-the-impact-of-a-health-system-wide-patient-blood-management-program
#19
Michael F Leahy, Kevin M Trentino, Colleen May, Stuart G Swain, Hun Chuah, Shannon L Farmer
BACKGROUND: Little is published on patient blood management (PBM) programs in hematology. In 2008 Western Australia announced a health system-wide PBM program with PBM staff appointments commencing in November 2009. Our aim was to assess the impact this program had on blood utilization and patient outcomes in intensive chemotherapy for acute leukemia or hematopoietic stem cell transplantation. STUDY DESIGN AND METHODS: A retrospective study of 695 admissions at two tertiary hospitals receiving intensive chemotherapy for acute leukemia or undergoing hematopoietic stem cell transplantation between July 2010 and December 2014 was conducted...
September 2017: Transfusion
https://www.readbyqxmd.com/read/28664397/peripheral-blood-monocyte-tolerance-alleviates-intraperitoneal-lipopolysaccharides-induced-neuroinflammation-in-rats-via-upregulating-the-cd200r-expression
#20
Liping Xia, Xin Xie, Yang Liu, Xiaoguang Luo
Neuroinflammation is an important pathogenesis of Parkinson's disease (PD). The peripheral immune system could produce profound effects on central immunities. The peripheral blood monocyte (PBM) immune tolerance is the refractoriness of immune system to avoid overactive peripheral inflammation. The PBM are also actively involved in central immune activities. There is evidence implying the probable failure of immune tolerance and impairment of CD200/CD200R signaling in PD patients. Here we aimed to explore the effects of PBM tolerance in peripheral LPS-induced neuroinflammation as well as the specific roles of CD200/CD200R pathway in PBM tolerance...
June 29, 2017: Neurochemical Research
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