Read by QxMD icon Read


Andrea Amaroli, Dimitrios Agas, Fulvio Laus, Vincenzo Cuteri, Reem Hanna, Maria Giovanna Sabbieti, Stefano Benedicenti
The literature has supported the concept of mesenchymal stromal cells (MSCs) in bone regeneration as one of the most important applications in oro-maxillofacial reconstructions. However, the fate of the transplanted cells and their effects on the clinical outcome is still uncertain. Photobiomodulation (PBM) plays an important role in the acceleration of tissue regeneration and potential repair. The aim of this in vitro study is to evaluate the effectiveness of PBM with 808 nm diode laser therapy, using a flat-top hand-piece delivery system at a higher-fluence (64 J/cm2 ) irradiation (1 W, continuous-wave) on bone marrow stromal cells (BMSCs)...
2018: Frontiers in Physiology
S M Ayuk, N N Houreld, H Abrahamse
The current study evaluated the photobiomodulatory effect of visible red light on cell proliferation and viability in various fibroblast diabetic models in vitro, namely, unstressed normal (N) and stressed normal wounded (NW), diabetic wounded (DW), hypoxic wounded (HW) and diabetic hypoxic wounded (DHW). Cells were irradiated at a wavelength of 660 nm with a fluence of 5 J/cm2 (11.23 mW/cm2 ), which related to an irradiation time of 7 min and 25 s. Control cells were not irradiated (0 J/cm2 ). Cells were incubated for 48 h and cellular proliferation was determined by measuring 5-bromo-2'-deoxyuridine (BrdU) in the S-phase (flow cytometry), while viability was assessed by the Trypan blue exclusion test and Apoptox-glo triplex assay...
March 8, 2018: Lasers in Medical Science
Adina Kleinerüschkamp, Patrick Meybohm, Niels Straub, Kai Zacharowski, Suma Choorapoikayil
BACKGROUND: Patient blood management (PBM) is a multidisciplinary concept focused on the management of anaemia, minimisation of iatrogenic blood loss and rational use of allogeneic blood products. The aims of this study were: (i) to analyse post-operative outcome in patients with liberal vs restrictive exposure to allogeneic blood products and (ii) to evaluate the cost-effectiveness of PBM in patients undergoing surgery. MATERIALS AND METHODS: A systematic literature review and meta-analysis were performed to compare post-operative complications in predominantly non-transfused patients (restrictive transfusion group) and patients who received one to three units of red blood cells (liberal transfusion group)...
February 16, 2018: Blood Transfusion, Trasfusione del Sangue
Simona Rimoldi, Genciana Terova, Chiara Ascione, Riccardo Giannico, Fabio Brambilla
Animal by-product meals from the rendering industry could provide a sustainable and commercially viable alternative to fishmeal (FM) in aquaculture, as they are rich in most essential amino acids and contain important amounts of water-soluble proteins that improve feed digestibility and palatability. Among them, poultry by-product meal (PBM) have given encouraging results in rainbow trout (Oncorhynchus mykiss). However, the introduction of new ingredients in the diet needs to be carefully evaluated since diet is one of the main factors affecting the gut microbiota, which is a complex community that contributes to host metabolism, nutrition, growth, and disease resistance...
2018: PloS One
V M A Voorn, L van Bodegom-Vos, C So-Osman
Despite the increasing availability of evidence in transfusion medicine literature, this evidence does not automatically find its way into practice. This is also applicable to patient blood management (PBM). It may concern the lack of implementation of effective new techniques or treatments, or it may apply to the (over)use of techniques and treatments (e.g. inappropriate transfusions) that have proven to be of limited benefit for patients (low-value care) and could be abandoned (de-implementation). In PBM literature, the implementation of restrictive transfusion thresholds and the de-implementation of inappropriate transfusions are described...
March 6, 2018: Transfusion Medicine
Ani Wang, Ruiqing Fan, Xuesong Zhou, Sue Hao, Xubin Zheng, Yulin Yang
Particulate matters (PMs) air pollution has become a serious environmental issue due to its great threat to human health. Herein, metal-organic complexes PBM-Zn1 and PBM-Zn2 coatings (noted as PBM-Zn-Filter) have been produced by hot-pressing method on various substrates for the first time. Layer-by-layer PBM-Zn-Filters were also obtained through varying hot-pressing cycles. The obtained PBM-Zn-Filters with high robustness show excellent performance in PMs removal. Especially, benefiting from larger conjugation system, micropore structure, lower pressure drop, higher electrostatic potential ζ and electron cloud exposed metal center of PBM-Zn2 (DFT calculations), PBM-Zn2@melamine foam-4 gives the highest removal rates, PM2...
March 5, 2018: ACS Applied Materials & Interfaces
Hasan Soleimani, Abdollah Amini, Soudabeh Taheri, Ensieh Sajadi, Sasha Shafikhani, Lucia A Schuger, Vijaya B Reddy, Seyed Kamran Ghoreishi, Ramin Pouriran, Sufan Chien, Mohammad Bayat
The purpose of the present scientific study was to analyze the effects of combined pulsed wave Photobiomodulation (PW PBM) and Curcumin on the microbial flora; in addition, the tensiometrical wounds properties for type one diabetes mellitus (TIDM) in an experimental animal model. TIDM induction was performed in thirty rats. In the entire animals, one full-thickness excision was implemented on their backs. Randomly, the divisions of rats into 5 groups took place. The primary group was considered as the control group and did not receive any treatment...
February 21, 2018: Journal of Photochemistry and Photobiology. B, Biology
Marcelo Victor Pires de Sousa, Masayoshi Kawakubo, Cleber Ferraresi, Beatriz Kaippert, Elisabeth Mateus Yoshimura, Michael R Hamblin
Photobiomodulation (PBM) is a simple, efficient and cost-effective treatment for both acute and chronic pain. We previously showed that PBM applied to the mouse head inhibited nociception in the foot. Nevertheless, the optimum parameters, location for irradiation, duration of the effect, and the mechanisms of action remain unclear. In the present study, the pain threshold in the right hind-paw of mice was studied, after PBM (810 nm CW laser, spot size 1 cm2 or 6 cm2 , 1.2-36 J/cm2 ) applied to various anatomical locations...
February 26, 2018: Journal of Biophotonics
Michael R Hamblin, Scott T Nelson, Justin R Strahan
BACKGROUND: Photobiomodulation (PBM) therapy is a rapidly growing approach to stimulate healing, reduce pain, increase athletic performance, and improve general wellness. OBJECTIVE: Applying PBM therapy over the site of a tumor has been considered to be a contraindication. However, since another growing use of PBM therapy is to mitigate the side effects of cancer therapy, this short review seeks to critically examine the evidence of whether PBM therapy is beneficial or harmful in cancer patients...
February 21, 2018: Photomedicine and Laser Surgery
Renata Luri Toma, Murilo Xavier Oliveira, Ana Cláudia Muniz Renno, E-Liisa Laakso
Muscle fatigue is a process influenced by several mechanisms such as concentration of metabolic substrates, changes in blood flow, and increases in reactive oxygen species that impair contractile muscle function. In this context, photobiomodulation has been investigated for preventing muscle fatigue, with reports of positive effects on muscle performance. This study aimed to investigate the effects of 904-nm LASER photobiomodulation on rectus femoris muscle performance in young women. Eighteen young women participated in a randomized, participant and assessor-blinded crossover trial with placebo control...
February 17, 2018: Lasers in Medical Science
Giovanni Mergoni, Paolo Vescovi, Silvana Belletti, Jacopo Uggeri, Samir Nammour, Rita Gatti
Photobiomodulation (PBM) is a non-invasive treatment that uses laser or led devices making its effects a response to light and not to heat. The possibility of accelerating dental implant osteointegration and orthodontic movements and the need to treat refractory bone lesions, such as bisphosphonate related osteonecrosis of the jaws, has led researchers to consider the effects of PBM on bone for dentistry purposes. The aim of our study was to investigate the effects of 915 nm light supplied with a GaAs diode laser on human osteoblasts in vitro...
February 15, 2018: Lasers in Medical Science
James Dudley
PURPOSE: The aim of this study was to quantify the coronal tooth structure reductions (CTSRs) resulting from a variety of different types of crown preparations performed by undergraduate dental students in a simulation clinic teaching program. MATERIALS AND METHODS: A total of 76 students each submitted 21 different crown preparations completed on typodont teeth, which were individually weighed and analyzed in relation to whole and sectioned reference teeth to calculate the CTSR resulting from each preparation...
February 15, 2018: International Journal of Prosthodontics
Mahesh Chandra Patra, Sangdun Choi
The toll/interleukin 1 receptor (TIR) domain-containing adaptor protein (TIRAP) plays an important role in the toll-like receptor (TLR) 2, TLR4, TLR7, and TLR9 signaling pathways. TIRAP anchors to phosphatidylinositol (PI) 4,5-bisphosphate (PIP2) on the plasma membrane and PI (3,4,5)-trisphosphate (PIP3) on the endosomal membrane and assists in recruitment of the myeloid differentiation primary response 88 protein to activated TLRs. To date, the structure and mechanism of TIRAP's membrane association are only partially understood...
2018: Frontiers in Immunology
Thaís Bianca Brandão, Karina Morais-Faria, Ana Carolina Prado Ribeiro, César Rivera, João Victor Salvajoli, Marcio Ajudarte Lopes, Joel B Epstein, Praveen R Arany, Gilberto de Castro, Cesar Augusto Migliorati, Alan Roger Santos-Silva
PURPOSE: The well-established clinical efficacy of photobiomodulation (PBM) therapy in management of oral mucositis (OM) is leading to increasing use in oncology care. This protection and enhanced repair of damage to mucosal tissue have led to the question of the potential effects of PBM therapy on pre-malignant and malignant cells. The purpose of this study was to examine the outcome of cancer therapy and incidence of tumor recurrence in locally advanced oral squamous cell carcinoma (OSCC) patients treated with PBM therapy for OM...
February 8, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
Zhangang Han, Xing Xin, Ran Zheng, Haitao Yu
To introduce Pb element into the crystal framework of a polyoxoanion, a series of hybrid compounds were synthesized and characterized: (H2bpp)5[PbMn(H2O)2]2H2{Mn[Mo6O12(OH)3(HPO4)3(PO4)]2}2·8H2O (1), (H2bpp)3[PbM(H2O)2]2H6{M[Mo6O12(OH)3(HPO4)3(PO4)]2}2·6H2O (M = Ni (2), Co (3)) and (H2bpp)3[PbCd(H2O)2]2H6{Cd[Mo6O12(OH)3(HPO4)3(PO4)]2}2·4H2O (4) (bpp = 1,3-bis(4-pyridyl)propane). Crystal structures were determined and characterized by IR, TG, XPS and single-crystal X-ray diffraction. Hybrids 1-4 have similar compositions; the inorganic moiety has a high-dimensional polyanionic arrangement formed from bi-metallic {PbM} subunits covalently bridging negative {M(P4Mo)2} clusters; the organic moiety is made up of protonated bpp cations that surround anionic clusters through many complex supramolecular interactions...
February 9, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
Sholeh Ghabraei, Nasim Chiniforush, Behnam Bolhari, Mohsen Aminsobhani, Abbas Khosarvi
Introduction: Achieving appropriate anesthesia in patients with symptomatic irreversible pulpitis in mandibular molars during endodontic treatment is always one of the most challenging aspects. Photobiomodulation (PBM) has been used in dentistry due to its anti-inflammatory properties and regenerative effects. This study evaluates the effects of PBM in the depth of anesthesia in inferior alveolar nerve block. Methods: In this randomized clinical trial, 44 patients requiring endodontic treatment in lower molar, left or right were selected, half of them were randomly treated with PBM therapy...
2018: Journal of Lasers in Medical Sciences
Kedong Yin, Benshuo Yang, Xuemei Li
In this paper, we investigate multiple attribute group decision making (MAGDM) problems where decision makers represent their evaluation of alternatives by trapezoidal fuzzy two-dimensional uncertain linguistic variable. To begin with, we introduce the definition, properties, expectation, operational laws of trapezoidal fuzzy two-dimensional linguistic information. Then, to improve the accuracy of decision making in some case where there are a sort of interrelationship among the attributes, we analyze partition Bonferroni mean (PBM) operator in trapezoidal fuzzy two-dimensional variable environment and develop two operators: trapezoidal fuzzy two-dimensional linguistic partitioned Bonferroni mean (TF2DLPBM) aggregation operator and trapezoidal fuzzy two-dimensional linguistic weighted partitioned Bonferroni mean (TF2DLWPBM) aggregation operator...
January 24, 2018: International Journal of Environmental Research and Public Health
Kellen K Andrilenas, Vijendra Ramlall, Jesse Kurland, Brandon Leung, Allen G Harbaugh, Trevor Siggers
Transcription factors IRF3, IRF5 and IRF7 (IRF3/5/7) have overlapping, yet distinct, roles in the mammalian response to pathogens. To examine the role that DNA-binding specificity plays in delineating IRF3/5/7-specific gene regulation we used protein-binding microarrays (PBMs) to characterize the DNA binding of IRF3/5/7 homodimers. We identified both common and dimer-specific DNA binding sites, and show that DNA-binding differences can translate into dimer-specific gene regulation. Central to the antiviral response, IRF3/5/7 regulate type I interferon (IFN) genes...
January 18, 2018: Nucleic Acids Research
Yen-Zhen Lu, Nilisha Fernando, Riccardo Natoli, Michele Madigan, Krisztina Valter
Photobiomodulation (PBM) with 670 nm light has been shown to accelerate wound healing in soft tissue injuries, and also to protect neuronal tissues. However, little data exist on its effects on the non-neuronal components of the retina, such as Müller cells (MCs), which are the principal macroglia of the retina that play a role in maintaining retinal homeostasis. The aim of this study was to explore the effects of 670 nm light on activated MCs using in vivo and in vitro stress models. Adult Sprague-Dawley rats were exposed to photo-oxidative damage (PD) for 24 h and treated with 670 nm light at 0, 3 and 14 days after PD...
January 17, 2018: Experimental Eye Research
Sandy Winfield Jere, Nicolette Nadene Houreld, Heidi Abrahamse
Photobiomodulation (PBM) modulates cellular processes to enhance diabetic wound healing. The photon energy activates wounded cells to proliferate and migrate. However, the signalling pathways responsible for these observations remain unknown. This study aimed to determine if PBM stimulates cellular proliferation and migration via the expression of epidermal growth factor (EGF) and activation of the Janus kinase/Signal transducer and activators of transcription (JAK/STAT) signalling pathway. Normal, wounded, diabetic and diabetic wounded cell models were exposed to PBM at a wavelength of 660nm and fluence of 5J/cm2 and incubated for 48h...
January 4, 2018: Journal of Photochemistry and Photobiology. B, Biology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"