Jennifer Garcia, Mihai Oltean, Carolina Rumbo, Lisa Sharkey, Stuart S Kaufman, Esther Ramos Boluda, Girish Gupte, Mercedes Martinez, Jang Moon, Vikram Raghu, Maria Cristina Segovia, Debra Sudan, Cécile Talbotec, Jonas Varkey, Gabriel E Gondolesi, George Mazariegos, Robert Venick
Intestinal transplant (ITx) rejection lacks a reliable noninvasive biomarker and rejection surveillance relies on serial endoscopies and mucosal biopsies followed by histologic assessment. Endoscopic biopsies are also essential for identifying other ITx-related complications such as infectious, allergic, and inflammatory graft enteritis as well as post-transplant lymphoproliferative disease or graft versus host disease. In spite of its central role in ITx, published guidelines on endoscopy and biopsy are lacking and significant variability between centers in terms of timing and technical performance exists...
September 19, 2023: Transplantation