keyword
MENU ▼
Read by QxMD icon Read
search

voltage sensor

keyword
https://www.readbyqxmd.com/read/28335313/triboelectric-hydrogen-gas-sensor-with-pd-functionalized-surface
#1
Sung-Ho Shin, Yang Hyeog Kwon, Young-Hwan Kim, Joo-Yun Jung, Junghyo Nah
Palladium (Pd)-based hydrogen (H₂) gas sensors have been widely investigated thanks to its fast reaction and high sensitivity to hydrogen. Various sensing mechanisms have been adopted for H₂ gas sensors; however, all the sensors must be powered through an external battery. We report here an H₂ gas sensor that can detect H₂ by measuring the output voltages generated during contact electrification between two friction surfaces. When the H₂ sensor, composed of Pd-coated ITO (indium tin oxide) and PET (polyethylene Terephthalate) film, is exposed to H₂, its output voltage is varied in proportion to H₂ concentration because the work function (WF) of Pd-coated surface changes, altering triboelectric charging behavior...
October 14, 2016: Nanomaterials
https://www.readbyqxmd.com/read/28333442/photoaffinity-ligand-for-the-inhalational-anesthetic-sevoflurane-allows-mechanistic-insight-into-potassium-channel-modulation
#2
Kellie A Woll, Wesley Peng, Qiansheng Liang, Lianteng Zhi, Jack A Jacobs, Lina Maciunas, Natarajan Bhanu, Benjamin A Garcia, Manuel Covarrubias, Patrick J Loll, William P Dailey, Roderic G Eckenhoff
Sevoflurane is a commonly used inhaled general anesthetic. Despite this, its mechanism of action remains largely elusive. Compared to other anesthetics, sevoflurane exhibits distinct functional activity. In particular, sevoflurane is a positive modulator of voltage-gated Shaker-related potassium channels (Kv1.x), which are key regulators of action potentials. Here, we report the synthesis and validation of azisevoflurane, a photoaffinity ligand for the direct identification of sevoflurane binding sites in the Kv1...
March 23, 2017: ACS Chemical Biology
https://www.readbyqxmd.com/read/28320963/conformational-dynamics-and-role-of-the-acidic-pocket-in-asic-ph-dependent-gating
#3
Sabrina Vullo, Gaetano Bonifacio, Sophie Roy, Niklaus Johner, Simon Bernèche, Stephan Kellenberger
Acid-sensing ion channels (ASICs) are proton-activated Na(+) channels expressed in the nervous system, where they are involved in learning, fear behaviors, neurodegeneration, and pain sensation. In this work, we study the role in pH sensing of two regions of the ectodomain enriched in acidic residues: the acidic pocket, which faces the outside of the protein and is the binding site of several animal toxins, and the palm, a central channel domain. Using voltage clamp fluorometry, we find that the acidic pocket undergoes conformational changes during both activation and desensitization...
March 20, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28316759/fourier-analysis-of-conservation-patterns-in-protein-secondary-structure
#4
Ashok Palaniappan, Eric Jakobsson
Residue conservation is a common observation in alignments of protein families, underscoring positions important in protein structure and function. Though many methods measure the level of conservation of particular residue positions, currently we do not have a way to study spatial oscillations occurring in protein conservation patterns. It is known that hydrophobicity shows spatial oscillations in proteins, which is characterized by computing the hydrophobic moment of the protein domains. Here, we advance the study of moments of conservation of protein families to know whether there might exist spatial asymmetry in the conservation patterns of regular secondary structures...
2017: Computational and Structural Biotechnology Journal
https://www.readbyqxmd.com/read/28303257/neurod2-regulates-stim1-expression-and-store-operated-calcium-entry-in-cortical-neurons
#5
Gokhan Guner, Gizem Guzelsoy, Fatma Sadife Isleyen, Gulcan Semra Sahin, Cansu Akkaya, Efil Bayam, Eser Ilgin Kotan, Alkan Kabakcioglu, Gulayse Ince-Dunn
Calcium signaling controls many key processes in neurons, including gene expression, axon guidance, and synaptic plasticity. In contrast to calcium influx through voltage- or neurotransmitter-gated channels, regulatory pathways that control store-operated calcium entry (SOCE) in neurons are poorly understood. Here, we report a transcriptional control of Stim1 (stromal interaction molecule 1) gene, which is a major sensor of endoplasmic reticulum (ER) calcium levels and a regulator of SOCE. By using a genome-wide chromatin immunoprecipitation and sequencing approach in mice, we find that NEUROD2, a neurogenic transcription factor, binds to an intronic element within the Stim1 gene...
January 2017: ENeuro
https://www.readbyqxmd.com/read/28301277/evidence-that-orai1-does-not-contribute-to-store-operated-trpc1-channels-in-vascular-smooth-muscle-cells
#6
Jian Shi, Francesc Miralles, Jean-Pierre Kinet, Lutz Birnbaumer, William A Large, Anthony P Albert
Ca(2+)-permeable store-operated channels (SOCs) mediate Ca(2+) entry pathways which are involved in many cellular functions such as contraction, growth, and proliferation. Prototypical SOCs are formed of Orai1 proteins and are activated by the endo/sarcoplasmic reticulum Ca(2+) sensor stromal interaction molecule 1 (STIM1). There is considerable debate about whether canonical transient receptor potential 1 (TRPC1) proteins also form store-operated channels (SOCs), and if they do, is Orai1 involved. We recently showed that stimulation of TRPC1-based SOCs involves store depletion inducing STIM1-evoked Gαq/PLCβ1 activity in contractile vascular smooth muscle cells (VSMCs)...
March 16, 2017: Channels
https://www.readbyqxmd.com/read/28296413/ac-electroosmosis-enhanced-nanoplasmofluidic-detection-of-ultralow-concentration-cytokine
#7
Yujing Song, Pengyu Chen, Meng Ting Chung, Robert Nidetz, Younggeun Park, Zhenhui Liu, Walker McHugh, Timothy T Cornell, Jianping Fu, Katsuo Kurabayashi
Label-free, nanoparticle-based plasmonic optical biosensing, combined with device miniaturization and microarray integration, has emerged as a promising approach for rapid, multiplexed biomolecular analysis. However, limited sensitivity prevents the wide use of such integrated label-free nanoplasmonic biosensors in clinical and life science applications where low-abundance biomolecule detection is needed. Here, we present a nanoplasmofluidic device integrated with microelectrodes for rapid, label-free analysis of a low-abundance cell signaling protein, detected by AC electroosmosis-enhanced localized surface plasmon resonance (ACE-LSPR) biofunctional nanoparticle imaging...
March 17, 2017: Nano Letters
https://www.readbyqxmd.com/read/28296153/corrigendum-plasmonic-nonlinear-optical-material-core-shell-nanorods-as-nanoscale-plasmon-modulators-and-optical-voltage-sensors
#8
Anxiang Yin, Qiyuan He, Zhaoyang Lin, Liang Luo, Yuan Liu, Sen Yang, Hao Wu, Mengning Ding, Yu Huang, Xiangfeng Duan
No abstract text is available yet for this article.
March 20, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28295737/dielectrophoresis-assisted-integration-of-1024-carbon-nanotube-sensors-into-a-cmos-microsystem
#9
Florent Seichepine, Jörg Rothe, Alexandra Dudina, Andreas Hierlemann, Urs Frey
Carbon-nanotube (CNT)-based sensors offer the potential to detect single-molecule events and picomolar analyte concentrations. An important step toward applications of such nanosensors is their integration in large arrays. The availability of large arrays would enable multiplexed and parallel sensing, and the simultaneously obtained sensor signals would facilitate statistical analysis. A reliable method to fabricate an array of 1024 CNT-based sensors on a fully processed complementary-metal-oxide-semiconductor microsystem is presented...
March 15, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28294128/a-cross-functional-nanostructured-platform-based-on-carbon-nanotube-si-hybrid-junctions-where-photon-harvesting-meets-gas-sensing
#10
F Rigoni, C Pintossi, G Drera, S Pagliara, G Lanti, P Castrucci, M De Crescenzi, L Sangaletti
A combination of the functionalities of carbon nanotube (CNT)-Si hybrid heterojunctions is presented as a novel method to steer the efficiency of the photovoltaic (PV) cell based on these junctions, and to increase the selectivity and sensitivity of the chemiresistor gas sensor operated with the p-doped CNT layer. The electrical characteristics of the junctions have been tracked by exposing the devices to oxidizing (NO2) and reducing (NH3) molecules. It is shown that when used as PV cells, the cell efficiency can be reversibly steered by gas adsorption, providing a tool to selectively dope the p-type layer through molecular adsorption...
March 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28293891/development-of-a-synthetic-switch-to-control-protein-stability-in-eukaryotic-cells-with-light
#11
Christof Taxis
In eukaryotic cells, virtually all regulatory processes are influenced by proteolysis. Thus, synthetic control of protein stability is a powerful approach to influence cellular behavior. To achieve this, selected target proteins are modified with a conditional degradation sequence (degron) that responds to a distinct signal. For development of a synthetic degron, an appropriate sensor domain is fused with a degron such that activity of the degron is under control of the sensor. This chapter describes the development of a light-activated, synthetic degron in the model organism Saccharomyces cerevisiae...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28287475/concentric-electrode-organic-electrochemical-transistors-case-study-for-selective-hydrazine-sensing
#12
Sébastien Pecqueur, Stéphane Lenfant, David Guérin, Fabien Alibart, Dominique Vuillaume
We report on hydrazine-sensing organic electrochemical transistors (OECTs) with a design consisting of concentric annular electrodes. The design engineering of these OECTs was motivated by the great potential of using OECT sensing arrays in fields such as bioelectronics. In this work, poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS)-based OECTs have been studied as aqueous sensors that are specifically sensitive to the lethal hydrazine molecule. These amperometric sensors have many relevant features for the development of hydrazine sensors, such as a sensitivity down to 10(-5) M of hydrazine in water, an order of magnitude higher selectivity for hydrazine than for nine other water-soluble common analytes, the capability to entirely recover its base signal after water flushing, and a very low operation voltage...
March 11, 2017: Sensors
https://www.readbyqxmd.com/read/28273916/herg-s4-s5-linker-acts-as-a-voltage-dependent-ligand-that-binds-to-the-activation-gate-and-locks-it-in-a-closed-state
#13
Olfat A Malak, Zeineb Es-Salah-Lamoureux, Gildas Loussouarn
Delayed-rectifier potassium channels (hERG and KCNQ1) play a major role in cardiac repolarization. These channels are formed by a tetrameric pore (S5-S6) surrounded by four voltage sensor domains (S1-S4). Coupling between voltage sensor domains and the pore activation gate is critical for channel voltage-dependence. However, molecular mechanisms remain elusive. Herein, we demonstrate that covalently binding, through a disulfide bridge, a peptide mimicking the S4-S5 linker (S4-S5L) to the channel S6 C-terminus (S6T) completely inhibits hERG...
December 2017: Scientific Reports
https://www.readbyqxmd.com/read/28272295/spectroscopic-on-line-monitoring-of-cu-w-contacts-erosion-in-hvcbs-using-optical-fibre-based-sensor-and-chromatic-methodology
#14
Zhixiang Wang, Gordon R Jones, Joseph W Spencer, Xiaohua Wang, Mingzhe Rong
Contact erosion is one of the most crucial factors affecting the electrical service lifetime of high-voltage circuit breakers (HVCBs). On-line monitoring the contacts' erosion degree is increasingly in demand for the sake of condition based maintenance to guarantee the functional operation of HVCBs. A spectroscopic monitoring system has been designed based upon a commercial 245 kV/40 kA S F 6 live tank circuit breaker with copper-tungsten (28 wt % and 72 wt %) arcing contacts at atmospheric S F 6 pressure. Three optical-fibre based sensors are used to capture the time-resolved spectra of arcs...
March 6, 2017: Sensors
https://www.readbyqxmd.com/read/28271102/switching-from-adduct-formation-to-electron-transfer-in-a-light-oxygen-voltage-domain-containing-the-reactive-cysteine
#15
Kathrin Magerl, Ivan Stambolic, Bernhard Dick
LOV (light-, oxygen- or voltage-sensitive) domains act as photosensory units of many prokaryotic and eukaryotic proteins. Upon blue light excitation they undergo a photocycle via the excited triplet state of their flavin chromophore yielding the flavin-cysteinyl adduct. Adduct formation is highly conserved among all LOV domains and constitutes the primary step of LOV domain signaling. But recently, it has been shown that signal propagation can also be triggered by flavin photoreduction to the neutral semiquinone offering new prospects for protein engineering...
March 8, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28270612/synchronous-circadian-voltage-rhythms-with-asynchronous-calcium-rhythms-in-the-suprachiasmatic-nucleus
#16
Ryosuke Enoki, Yoshiaki Oda, Michihiro Mieda, Daisuke Ono, Sato Honma, Ken-Ichi Honma
The suprachiasmatic nucleus (SCN), the master circadian clock, contains a network composed of multiple types of neurons which are thought to form a hierarchical and multioscillator system. The molecular clock machinery in SCN neurons drives membrane excitability and sends time cue signals to various brain regions and peripheral organs. However, how and at what time of the day these neurons transmit output signals remain largely unknown. Here, we successfully visualized circadian voltage rhythms optically for many days using a genetically encoded voltage sensor, ArcLightD...
March 7, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28269982/effective-contact-potential-of-thin-film-metal-insulator-nanostructures-and-its-role-in-self-powered-nanofilm-x-ray-sensors
#17
Davide Brivio, Earl Ada, Erno Sajo, Piotr Zygmanski
We studied the effective contact potential difference (ECPD) of thin film nanostructures and its role in self-powered X-ray sensors, which use the high-energy current detection scheme. We compared the response to kilovoltage X-rays of several nanostructures made of disparate combinations of conductors (Al, Cu, Ta, ITO) and oxides (SiO2, Ta2O5, Al2O3). We measured current-voltage curves in parallel-plate configuration separated by an air gap and determined three characteristic parameters: current at zero voltage bias I0, the voltage offset for zero current ECPD, and saturation current Isat...
March 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28269470/can-we-make-a-carpet-smart-enough-to-detect-falls
#18
Fadi Muheidat, Harry W Tyrer
In this paper, we have enhanced smart carpet, which is a floor based personnel detector system, to detect falls using a faster but low cost processor. Our hardware front end reads 128 sensors, with sensors output a voltage due to a person walking or falling on the carpet. The processor is Jetson TK1, which provides more computing power than before. We generated a dataset with volunteers who walked and fell to test our algorithms. Data obtained allowed examining data frames (a frame is a single scan of the carpet sensors) read from the data acquisition system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28269366/a-triboelectric-motion-sensor-in-wearable-body-sensor-network-for-human-activity-recognition
#19
Hui Huang, Xian Li, Ye Sun
The goal of this study is to design a novel triboelectric motion sensor in wearable body sensor network for human activity recognition. Physical activity recognition is widely used in well-being management, medical diagnosis and rehabilitation. Other than traditional accelerometers, we design a novel wearable sensor system based on triboelectrification. The triboelectric motion sensor can be easily attached to human body and collect motion signals caused by physical activities. The experiments are conducted to collect five common activity data: sitting and standing, walking, climbing upstairs, downstairs, and running...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28268701/dual-mode-cmos-analog-front-end-afe-for-electrical-impedance-spectroscopy-eis-systems
#20
Virgilio Valente, Dai Jiang, Andreas Demosthenous
This paper presents the operation of a dual-mode wideband CMOS analog front-end (AFE) for electrical impedance spectroscopy. The chip combines two current-readout (CR) channels and four voltage-readout (VR) channels suitable for both bipolar and tetrapolar EIS analysis. The chip addresses the need for flexible readout units for real-time simultaneous single-cell and large scale tissue/organ analysis. Postlayout simulations show that the VR channel is capable of wideband operation up to 12 MHz with noise floor as low as 16...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
keyword
keyword
51240
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"