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https://www.readbyqxmd.com/read/28730806/investigation-of-exciton-recombination-zone-in-quantum-dot-light-emitting-diodes-using-a-fluorescent-probe
#1
Xiaoyu Huang, Heng Zhang, Dingxin Xu, Feng Wen, Shuming Chen
Exciton recombination zone, where the photons are generated, can greatly affect the performance such as the efficiency, the color purity of the quantum dot (QD) light-emitting diodes (QLEDs). To probe the exciton recombination zone, 4-(dicyanomethylene)-2-t-butyl-6(1,1,7,7 -tetramethyljulolidyl-9-enyl)-4H-pyran (DCJTB) is doped into the charge transport layer as a fluorescent sensor; by monitoring the Förster resonant energy transfer (FRET) between QD and DCJTB, the location of the recombination zone can be determined...
July 21, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28727018/evaluation-of-electrical-broad-bandwidth-impedance-spectroscopy-as-a-tool-for-body-composition-measurement-in-cows-in-comparison-with-body-measurements-and-the-deuterium-oxide-dilution-method
#2
C T Schäff, U Pliquett, A Tuchscherer, R Pfuhl, S Görs, C C Metges, H M Hammon, C Kröger-Koch
Body fatness and degree of body fat mobilization in cows vary enormously during their reproduction cycle and influence energy partitioning and metabolic adaptation. The objective of the study was to test bioelectrical impedance spectroscopy (BIS) as a method for predicting fat depot mass (FDM), in living cows. The FDM is defined as the sum of subcutaneous, omental, mesenteric, retroperitoneal, and carcass fat mass. Bioelectrical impedance spectroscopy is compared with the prediction of FDM from the deuterium oxide (DO) dilution method and from body conformation measurements...
May 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28726745/dual-source-linear-energy-prediction-line-p-model-in-the-context-of-wsns
#3
Faisal Ahmed, Gert Tamberg, Yannick Le Moullec, Paul Annus
Energy harvesting technologies such as miniature power solar panels and micro wind turbines are increasingly used to help power wireless sensor network nodes. However, a major drawback of energy harvesting is its varying and intermittent characteristic, which can negatively affect the quality of service. This calls for careful design and operation of the nodes, possibly by means of, e.g., dynamic duty cycling and/or dynamic frequency and voltage scaling. In this context, various energy prediction models have been proposed in the literature; however, they are typically compute-intensive or only suitable for a single type of energy source...
July 20, 2017: Sensors
https://www.readbyqxmd.com/read/28723210/bipolar-electrodes-with-100-current-efficiency-for-sensors
#4
Xiaowei Zhang, Qingfeng Zhai, Huanhuan Xing, Jing Li, Erkang Wang
A bipolar electrode (BPE) is an electron conductor that is embedded in the electrolyte solution without the direct connection with the external power source (driving electrode). When the sufficient voltage was provided, the two poles of BPE promote different oxidation and reduction reactions. During the past few years, BPEs with wireless feature and easy integration showed great promise in the various fields including asymmetric modification/synthesis, motion control, targets enrichment/separation, and chemical sensing/biosensing combined with the quantitative relationship between two poles of BPE...
March 24, 2017: ACS Sensors
https://www.readbyqxmd.com/read/28716755/construction-of-an-amperometric-glycated-hemoglobin-biosensor-based-on-au-pt-bimetallic-nanoparticles-and-poly-indole-5-carboxylic-acid-modified-au-electrode
#5
Utkarsh Jain, Shaivya Gupta, Nidhi Chauhan
The glucose level measurement in the diabetic patient plays a vital role in identification of the treatments going on and it also provides the control over the diabetics. A new electrochemical sensing device was constructed for determination of glycated hemoglobin (HbA1c) in whole blood samples. Fructosyl amine oxidase (FAO) was bioconjugated onto hybrid nanocomposite i.e., gold nanoparticles-platinum nanoparticles (AuNPs-PtNPs) and poly indole-5-carboxylic acid (PIN5COOH), deposited electrochemically on gold electrode...
July 14, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28715004/an-implantable-multimodal-sensor-for-oxygen-neurotransmitters-and-electrophysiology-during-spreading-depolarization-in-the-deep-brain
#6
Caddy N Hobbs, Justin A Johnson, Matthew D Verber, R Mark Wightman
Brain tissue injury is often accompanied by spreading depolarization (SD) events, marked by widespread cellular depolarization and cessation of neuronal firing. SD recruits viable tissue into the lesion, making it a focus for intervention. During SD, drastic fluctuations occur in ion gradients, extracellular neurotransmitter concentrations, cellular metabolism, and cerebral blood flow. Measuring SD requires a multimodal approach to capture the array of changes. However, the use of multiple sensors can inflict tissue damage...
July 17, 2017: Analyst
https://www.readbyqxmd.com/read/28707896/smart-floor-with-integrated-triboelectric-nanogenerator-as-energy-harvester-and-motion-sensor
#7
Chuan He, Weijun Zhu, Baodong Chen, Liang Xu, Tao Jiang, Chang Bao Han, Guang Qin Gu, Dichen Li, Zhong Lin Wang
A smart floor is demonstrated by integrating a square-frame triboelectric nanogenerator (SF-TENG) into a standard wood floor. The smart floor has two working modes based on two pairs of triboelectric materials: one is purposely chosen polytetrafluoroethylene (PTFE) films and aluminum (Al) balls, the other is the floor itself and the objects that can be triboelectrically charged, such as basketball, shoe soles, and scotch tape, etc. Utilizing the Al balls enclosed inside shallow boxes, the smart floor is capable of harvesting vibrational energy, hence provides a non-intrusive way to detect the sudden fall of the elderly...
July 14, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28707577/high-performance-enzyme-free-glucose-sensor-with-co-cu-nanorod-arrays-on-si-substrates
#8
Alexander Marcus Seifalian, Haji Shirinzadeh, Abolfazl Yazdanpanah, Dimitrios Karponis, Mohammad Tahmasbi, Masoud Mozafari
BACKGROUND: Glucose sensors have been extensively researched and manufactured a tool for clinical diabetes diagnosis. Although some kinds of electrochemical enzymatic glucose sensors have been commercially successful, however, there is still room for improvement, in selectivity and reliability of these sensors. Because of the intrinsic disadvantages of enzymes, such as high fabrication cost and poor stability, non-enzymatic glucose sensors have recently promoted as next generation diagnostic tool due to their relatively low cost, high stability, prompt response, and accuracy...
July 13, 2017: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/28706455/escitalopram-a-selective-serotonin-reuptake-inhibitor-inhibits-voltage-dependent-k-channels-in-coronary-arterial-smooth-muscle-cells
#9
Han Sol Kim, Hongliang Li, Hye Won Kim, Sung Eun Shin, Mi Seon Seo, Jin Ryeol An, Kwon-Soo Ha, Eun-Taek Han, Seok-Ho Hong, Il-Whan Choi, Grace Choi, Dae-Sung Lee, Won Sun Park
We investigated the inhibitory effect of escitalopram, a selective serotonin reuptake inhibitor (SSRI), on voltage-dependent K(+) (Kv) channels in freshly separated from rabbit coronary arterial smooth muscle cells. The application of escitalopram rapidly inhibited vascular Kv channels. Kv currents were progressively inhibited by an increase in the concentrations of escitalopram, suggesting that escitalopram inhibited vascular Kv currents in a concentration-dependent manner. The IC50 value and Hill coefficient for escitalopram-induced inhibition of Kv channels were 9...
July 2017: Korean Journal of Physiology & Pharmacology
https://www.readbyqxmd.com/read/28705808/molecular-basis-of-altered-herg1-channel-gating-induced-by-ginsenoside-rg3
#10
Alison Gardner, Wei Wu, Steven Thomson, Eva-Maria Zangerl-Plessl, Anna Stary-Weinzinger, Michael Sanguinetti
Outward current conducted by human ether-a-g-go-related gene type 1 (hERG1) channels is a major determinant of action potential repolarization in the human ventricle. Ginsenoside 20(S)-Rg3 (Rg3), an alkaloid isolated from the root of Panax ginseng slows the rate of hERG1 deactivation, induces channels to open at more negative potentials than normal and increases current magnitude. The onset of Rg3 action is extremely fast, suggesting that it binds to an extracellular accessible site on the channel to alter its gating...
July 13, 2017: Molecular Pharmacology
https://www.readbyqxmd.com/read/28687606/camp-dependent-regulation-of-iks-single-channel-kinetics
#11
Emely Thompson, Jodene Eldstrom, Maartje Westhoff, Donald McAfee, Elise Balse, David Fedida
The delayed potassium rectifier current, IKs , is composed of KCNQ1 and KCNE1 subunits and plays an important role in cardiac action potential repolarization. During β-adrenergic stimulation, 3'-5'-cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) phosphorylates KCNQ1, producing an increase in IKs current and a shortening of the action potential. Here, using cell-attached macropatches and single-channel recordings, we investigate the microscopic mechanisms underlying the cAMP-dependent increase in IKs current...
July 7, 2017: Journal of General Physiology
https://www.readbyqxmd.com/read/28687180/a-patient-with-early-myoclonic-encephalopathy-eme-with-a-de-novo-kcnq2-mutation
#12
Karin Kojima, Kentaro Shirai, Mizuki Kobayashi, Akihiko Miyauchi, Hirotomo Saitsu, Naomichi Matsumoto, Hitoshi Osaka, Takanori Yamagata
BACKGROUND: The potassium voltage-gated channel subfamily Q member 2 (KCNQ2) gene has been reported to be associated with various types of epilepsy, including benign familial neonatal seizure (BFNS), early infantile epileptic encephalopathy (EIEE), and unclassified early onset encephalopathies. We herein report a patient with early myoclonic encephalopathy (EME) caused by a KCNQ2 mutation. CASE REPORT: A male infant started to exhibit erratic myoclonus several days after birth and apnea attacks lasting for seconds with desaturation...
July 4, 2017: Brain & Development
https://www.readbyqxmd.com/read/28686013/inline-shunt-flow-monitor-for-hydrocephalus
#13
Chuchu Qin, Brian Stamos, Purnendu K Dasgupta
In hydrocephalus, cerebrospinal fluid (CSF) builds up in the cranial cavity causing swelling of the head and potentially brain damage. A shunt to drain the fluid into a body cavity is now universally used, but failure is all too common. Techniques for ascertaining shunt failure are time-consuming, expertise-dependent, and often inconclusive. We report here an inline system that reliably and quantitatively measures the CSF flow rate. The system uses a single thermistor to both heat the surrounding and to sense the temperature...
July 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28676720/a-channelopathy-mutation-in-the-voltage-sensor-discloses-contributions-of-a-conserved-phenylalanine-to-gating-properties-of-kv1-1-channels-and-ataxia
#14
Sonia Hasan, Cecilia Bove, Gabriella Silvestri, Elide Mantuano, Anna Modoni, Liana Veneziano, Lara Macchioni, Therese Hunter, Gary Hunter, Mauro Pessia, Maria Cristina D'Adamo
Channelopathy mutations prove informative on disease causing mechanisms and channel gating dynamics. We have identified a novel heterozygous mutation in the KCNA1 gene of a young proband displaying typical signs and symptoms of Episodic Ataxia type 1 (EA1). This mutation is in the S4 helix of the voltage-sensing domain and results in the substitution of the highly conserved phenylalanine 303 by valine (p.F303V). The contributions of F303 towards K(+) channel voltage gating are unclear and here have been assessed biophysically and by performing structural analysis using rat Kv1...
July 4, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28675615/betamethasone-based-chiral-electrochemical-sensor-coupled-to-chemometric-methods-for-determination-of-mandelic-acid-enantiomers
#15
Marjan Borazjani, Ali Mehdinia, Ali Jabbari
A chiral biosensing platform was developed using betamethasone (BMZ) as chiral recognition element through multilayered electrochemical deposition of BMZ, overoxidized polypyrrole, and nanosheets of graphene (OPPy-BMZ/GR), for enantio-recognition of mandelic acid (MA) enantiomers. The deposited film was characterized by scanning electron microscopy, differential pulse voltammetry, cyclic voltammetry, and electrochemical impedance spectroscopy. It was shown that the chiral sensing platform can discriminate R- and S-MA differential pulse voltammetry signals, at the voltages of 1...
July 4, 2017: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/28672832/a-multi-resolution-mode-cmos-image-sensor-with-a-novel-two-step-single-slope-adc-for-intelligent-surveillance-systems
#16
Daehyeok Kim, Minkyu Song, Byeongseong Choe, Soo Youn Kim
In this paper, we present a multi-resolution mode CMOS image sensor (CIS) for intelligent surveillance system (ISS) applications. A low column fixed-pattern noise (CFPN) comparator is proposed in 8-bit two-step single-slope analog-to-digital converter (TSSS ADC) for the CIS that supports normal, 1/2, 1/4, 1/8, 1/16, 1/32, and 1/64 mode of pixel resolution. We show that the scaled-resolution images enable CIS to reduce total power consumption while images hold steady without events. A prototype sensor of 176 × 144 pixels has been fabricated with a 0...
June 25, 2017: Sensors
https://www.readbyqxmd.com/read/28671813/self-powered-acceleration-sensor-based-on-liquid-metal-triboelectric-nanogenerator-for-vibration-monitoring
#17
Binbin Zhang, Lei Zhang, Weili Deng, Long Jin, Fengjun Chun, Hong Pan, Bingni Gu, Haitao Zhang, Zekai Lv, Weiqing Yang, Zhong Lin Wang
Acceleration sensor is an essential component of the vibration measurement, while the passivity and sensitivity are the pivotal features for its application. Here, we report a self-powered and high sensitive acceleration sensor based on triboelectric nanogenerator composed of liquid metal mercury droplet (LMMD) and nanofiber-networked polyvinylidene fluoride (nn-PVDF) film. Due to the ultrahigh surface-to-volume ratio of nn-PVDF film and high surface tension, high mass density, high elastic as well as mechanical robustness of LMMD, the open-circuit voltage and short-circuit current reach up to 15...
July 3, 2017: ACS Nano
https://www.readbyqxmd.com/read/28670898/redox-active-binary-logic-gate-circuit-for-homeland-security
#18
Pramod Gaikwad, Kavita Kadlag, Manasa Nambiar, Mruthyunjayachari Chattanahalli Devendrachari, Shambhulinga Aralekallu, Alagar Raja Kottaichamy, Zahid Manzoor Bhat, Ravikumar Thimmappa, Shahid Pottachola Shafi, Musthafa Ottakam Thotiyl
Bipolar junction transistors are at the frontiers of modern electronics owing to their discrete voltage regulated operational levels. Here we report a redox active binary logic gate (RLG) which can store a "0" and "1" with distinct operational levels, albeit without an external voltage stimuli. In the RLG, a shorted configuration of half-cell electrodes provided the logic low level and decoupled configuration relaxed the system to the logic high level due to self-charge injection into the redox active polymeric system...
July 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28666963/a-novel-kcna1-mutation-in-a-patient-with-paroxysmal-ataxia-myokymia-painful-contractures-and-metabolic-dysfunctions
#19
Paola Imbrici, Concetta Altamura, Francesca Gualandi, Giuseppe Felice Mangiatordi, Marcella Neri, Giovanni De Maria, Alessandra Ferlini, Alessandro Padovani, Maria Cristina D'Adamo, Orazio Nicolotti, Mauro Pessia, Diana Conte, Massimiliano Filosto, Jean-Francois Desaphy
Episodic ataxia type 1 (EA1) is a human dominant neurological syndrome characterized by continuous myokymia, episodic attacks of ataxic gait and spastic contractions of skeletal muscles that can be triggered by emotional stress and fatigue. This rare disease is caused by missense mutations in the KCNA1 gene coding for the neuronal voltage gated potassium channel Kv1.1, which contributes to nerve cell excitability in the cerebellum, hippocampus, cortex and peripheral nervous system. We identified a novel KCNA1 mutation, E283K, in an Italian proband presenting with paroxysmal ataxia and myokymia aggravated by painful contractures and metabolic dysfunctions...
June 28, 2017: Molecular and Cellular Neurosciences
https://www.readbyqxmd.com/read/28664732/palladium-mediated-synthesis-of-a-near-ir-fluorescent-k-sensor
#20
H M Dhammika Bandara, Zhengmao Hua, Mei Zhang, Steven M Pauff, Stephen C Miller, Elizabeth A Colby Davie, William R Kobertz
Potassium (K(+)) exits electrically excitable cells during normal and pathophysiological activity. Currently, K(+)-sensitive electrodes and electrical measurements are the primary tools to detect K(+) fluxes. Here we describe the synthesis of a near-IR, oxazine fluorescent K(+) sensor (KNIR-1) with a dissociation constant suited for detecting changes in intracellular and extracellular K+ concentrations. KNIR-1 treatment of cells expressing voltage-gated K(+) channels enabled the visualization of intracellular K+ depletion upon channel opening and restoration of cytoplasmic K(+) after channel closing...
June 30, 2017: Journal of Organic Chemistry
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