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Somatosensory Evoked Potentials

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https://www.readbyqxmd.com/read/29772366/giant-cell-ependymoma-of-cervical-medullary-junction-a-case-report-of-a-long-term-survivor-and-review-of-literature
#1
REVIEW
Martina Cappelletti, Andrea G Ruggeri, Giorgia Iacopino, Roberto Delfini
Ependymoma accounts for 3-9% of all neuroepithelial tumors. The giant cell ependymoma is a rare and distinct variant, of which only twenty-two cases have been described in literature. Starting from 2007, the WHO acknowledged this rare subtype. The cytological features of GCE are the presence of pleomorphic giant cells with several cellular atypias, which at intra-operative frozen diagnosis may appear to be high-grade glial lesions. Despite its apparently malignant histology, GCE seems to be a neoplasm with a relatively good prognosis...
May 14, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29753579/a-reappraisal-of-pain-paired-associative-stimulation-suggesting-motor-inhibition-at-spinal-level
#2
Martine Gavaret, Samar S Ayache, Veit Mylius, Alaa Mhalla, Moussa A Chalah, Jean-Pascal Lefaucheur
OBJECTIVES: Paired associative stimulation (PAS) can modulate motor excitability and consists of delivering repeated pairs of peripheral sensory stimulation combined with transcranial magnetic stimulation (TMS) over the contralateral motor cortex. Our objective was to evaluate the effect of a PAS protocol using a painful stimulation. METHODS: Ten healthy volunteers underwent pain-PAS protocol consisting of 90 pairs of nociceptive stimulus over the right hand followed by an image-guided navigated TMS of the contralateral motor cortex, delivered at 0...
May 9, 2018: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/29753106/feasibility-of-imaging-evoked-activity-throughout-the-rat-brain-using-electrical-impedance-tomography
#3
Mayo Faulkner, Sana Hannan, Kirill Aristovich, James Avery, David Holder
Electrical Impedance Tomography (EIT) is an emerging technique which has been used to image evoked activity during whisker displacement in the cortex of an anaesthetised rat with a spatiotemporal resolution of 200 μm and 2 ms. The aim of this work was to extend EIT to image not only from the cortex but also from deeper structures active in somatosensory processing, specifically the ventral posterolateral (VPL) nucleus of the thalamus. The direct response in the cortex and VPL following 2 Hz forepaw stimulation were quantified using a 57-channel epicortical electrode array and a 16-channel depth electrode...
May 9, 2018: NeuroImage
https://www.readbyqxmd.com/read/29751769/repeated-injections-of-human-umbilical-cord-blood-derived-mesenchymal-stem-cells-significantly-promotes-functional-recovery-in-rabbits-with-spinal-cord-injury-of-two-noncontinuous-segments
#4
Chaohua Yang, Gaoju Wang, Fenfen Ma, Baoqing Yu, Fancheng Chen, Jin Yang, Jianjun Feng, Qing Wang
BACKGROUND: Spinal cord injuries (SCIs) are sustained by an increasing number of patients each year worldwide. The treatment of SCIs has long been a hard nut to crack for doctors around the world. Mesenchymal stem cells (MSCs) have shown benefits for the repair of SCI and recovery of function. Our present study aims to investigate the effects of intravenously infused human umbilical cord blood-derived MSCs (hUCB-MSCs) on functional recovery after subacute spinal cord compression injury of two noncontinuous segments...
May 11, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29750263/independent-early-and-late-sensory-processes-for-proprioceptive-integration-when-planning-a-step
#5
Anahid H Saradjian, Normand Teasdale, Jean Blouin, Laurence Mouchnino
Somatosensory inputs to the cortex undergo an early and a later stage of processing which are characterized by an early and a late somatosensory evoked potentials (SEP). The early response is highly representative of the stimulus characteristics whereas the late response reflects a more integrative, task specific, stage of sensory processing. We hypothesized that the later processing stage is independent of the early processing stage. We tested the prediction that a reduction of the first volley of input to the cortex should not prevent the increase of the late SEP...
May 10, 2018: Cerebral Cortex
https://www.readbyqxmd.com/read/29742889/intraoperative-neurophysiological-monitoring-a-review-of-techniques-used-for-brain-tumor-surgery-in-children
#6
REVIEW
Keewon Kim, Charles Cho, Moon-Suk Bang, Hyung-Ik Shin, Ji-Hoon Phi, Seung-Ki Kim
Intraoperative monitoring (IOM) utilizes electrophysiological techniques as a surrogate test and evaluation of nervous function while a patient is under general anesthesia. They are increasingly used for procedures, both surgical and endovascular, to avoid injury during an operation, examine neurological tissue to guide the surgery, or to test electrophysiological function to allow for more complete resection or corrections. The application of IOM during pediatric brain tumor resections encompasses a unique set of technical issues...
May 2018: Journal of Korean Neurosurgical Society
https://www.readbyqxmd.com/read/29739869/synaptic-release-of-acetylcholine-rapidly-suppresses-cortical-activity-by-recruiting-muscarinic-receptors-in-layer-4
#7
Rajan Dasgupta, Frederik Seibt, Michael Beierlein
Cholinergic afferents from the basal forebrain (BF) can influence cortical activity on rapid time scales, enabling sensory information processing and exploratory behavior. However, our understanding of how synaptically released acetylcholine (ACh) influences cellular targets in distinct cortical layers remains incomplete. Previous studies have shown that rapid changes in cortical dynamics induced by phasic BF activity can be mediated by the activation of nicotinic ACh receptors (nAChRs) expressed in distinct types of GABAergic interneurons...
May 8, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29729461/high-risk-surgical-maneuvers-for-impending-true-positive-intraoperative-neurologic-monitoring-alerts-experience-in-3139-consecutive-spine-surgeries
#8
Shujie Wang, Qiyi Li, Jie Zhu, Jianxiong Shen, Ye Tian, Yong Hu, Jianguo Zhang
BACKGROUND: Intraoperative neurologic monitoring (IONM) has become an essential component for decreasing the incidence of spinal cord injury during many spine surgeries. Many high-risk surgical maneuvers that result in significant IONM alerts have not been reported systematically. Our objective in this study was to thoroughly summarize some common high-risk surgical points associated with IONM alerts in various spine surgeries. METHODS: A total of 62 patients with true-positive IONM alerts from 3139 spine surgeries were enrolled between November 2010 and April 2017...
May 2, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29710747/effect-of-rehabilitation-on-the-somatosensory-evoked-potentials-and-gait-performance-of-hemiparetic-stroke-patients
#9
Hyun S Yoon, Young J Cha, Min K Sohn, Joshua Sung H You
BACKGROUND: Gait performance of stroke patients is affected by impaired sensory ability. The purpose of the present study was to determine the relationship between somatosensory-evoked potential (SSEP) parameters and gait performance in hemiparetic stroke patients. METHODS: A convenience sample of 17 hemiparetic stroke patients (mean age 60.11 ± 8.83 years; 10 women; right hemiplegia: 10, left hemiplegia: 7) were recruited for the present study. The Electro Synergy system (Viasys Healthcare; San Diego, CA, USA) was used for SSEP evaluation...
April 18, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29709735/safeness-and-utility-of-concomitant-intraoperative-monitoring-with-intraoperative-magnetic-resonance-imaging-in-children-a-pilot-study
#10
Sandra Dias, Johannes Sarnthein, Elisabeth Jehli, Marian Christoph Neidert, Luca Regli, Oliver Bozinov
OBJECTIVE: High-field intraoperative MR (ioMRI) has become increasingly available in neurosurgery centers. There is little experience with the combination of ioMRI with intraoperative neurophysiological neuromonitoring (IONM). We provide a first series of pediatric patients undergoing brain tumor surgery with 3T ioMRI and IONM. METHODS: We conducted a pilot study were we included all consecutive children operated for brain tumors between October 2013 and April 2016 where concomitant ioMRI and somatosensory evoked potentials (SEP) and motor evoked potentials (MEP) were used...
April 27, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29707900/an-observational-case-series-of-spinal-cord-stimulation-waveforms-visualized-on-intraoperative-neuromonitoring
#11
Steven M Falowski
INTRODUCTION: Intraoperative neuromonitoring for spinal cord stimulation uses electromyography (EMG) responses to determine myotomal coverage as a marker for dermatomal coverage. These responses are utilized to determine the orientation of the electrode. Somatosensory evoked potential (SSEP) collision testing can also be used in which sensory signals are decreased and/or eliminated when stimulation is activated. METHODS: Fifteen patients were observed in the study...
April 29, 2018: Neuromodulation: Journal of the International Neuromodulation Society
https://www.readbyqxmd.com/read/29704223/low-thoracic-erector-spinae-plane-block-for-perioperative-analgesia-in-lumbosacral-spine-surgery-a-case-series
#12
Josh P Melvin, Rudolph J Schrot, George M Chu, Ki Jinn Chin
PURPOSE: Severe postoperative pain following spine surgery is a significant cause of morbidity, extended length of facility stay, and marked opioid usage. The erector spinae plane (ESP) block anesthetizes the dorsal rami of spinal nerves that innervate the paraspinal muscles and bony vertebra. We describe the use of low thoracic ESP blocks as part of multimodal analgesia in lumbosacral spine surgery. CLINICAL FEATURES: We performed bilateral ESP blocks at the T10 or T12 level in six cases of lumbosacral spine surgery: three lumbar decompressions, two sacral laminoplasties, and one coccygectomy...
April 27, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29699821/atlas-of-optimal-coil-orientation-and-position-for-tms-a-computational-study
#13
Jose Gomez-Tames, Atsushi Hamasaka, Ilkka Laakso, Akimasa Hirata, Yoshikazu Ugawa
BACKGROUND: Transcranial magnetic stimulation (TMS) activates target brain structures in a non-invasive manner. The optimal orientation of the TMS coil for the motor cortex is well known and can be estimated using motor evoked potentials. However, there are no easily measurable responses for activation of other cortical areas and the optimal orientation for these areas is currently unknown. OBJECTIVE: This study investigated the electric field strength, optimal coil orientation, and relative locations to optimally stimulate the target cortex based on computed electric field distributions...
April 17, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29696497/cerebellar-ataxia-neuropathy-vestibular-areflexia-syndrome-canvas-with-chronic-cough-and-preserved-muscle-stretch-reflexes-evidence-for-selective-sparing-of-afferent-ia-fibres
#14
Jon Infante, Antonio García, Karla M Serrano-Cárdenas, Rocío González-Aguado, José Gazulla, Enrique M de Lucas, José Berciano
The aim of this study was to describe five patients with cerebellar ataxia, neuropathy and vestibular areflexia syndrome (CANVAS) with chronic cough and preserved limb muscle stretch reflexes. All five patients were in the seventh decade of age, their gait imbalance having been initiated in the fifth decade. In four patients cough antedated gait imbalance between 15 and 29 years; cough was spasmodic and triggered by variable factors. Established clinical picture included severe hypopallesthesia predominating in the lower limbs with postural imbalance, and variable degree of cerebellar axial and appendicular ataxia, dysarthria and horizontal gaze-evoked nystagmus...
April 25, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29694662/technique-of-localizing-the-central-sulcus-under-awaking-anesthesia-for-treatmeat-of-gliomas-in-or-near-motor-areas
#15
Wan Yi, Shujun Xu, Xingang Li, Xiangyu Ma
AIM: This study aimed to study the protective effect of intraoperative awakening and central sulcus location on motor function for patients with gliomas located in motor areas. METHODS: A total of 68 patients with gliomas in motor areas were intubated with a laryngeal mask and rapidly underwent craniotomy without scalp clips and awakening, followed by localization of the central sulcus by somatosensory evoked potential. To protect brain function, we resected the greatest degree of tumor as possible and then finished the close-skull under an awakened state or general anesthesia...
April 6, 2018: Turkish Neurosurgery
https://www.readbyqxmd.com/read/29689487/evoked-potentials-predict-psychomotor-development-in-neonates-with-normal-mri-after-hypothermia-for-hypoxic-ischemic-encephalopathy
#16
Elisa Cainelli, Daniele Trevisanuto, Francesco Cavallin, Renzo Manara, Agnese Suppiej
OBJECTIVES: To assess the prognostic role of evoked potentials (EP) in neonates with normal magnetic resonance imaging (MRI) after therapeutic hypothermia (TH) for hypoxic-ischemic encephalopathy (HIE). METHODS: Thirty-five neonates recruited for TH because of HIE, having normal neonatal MRI, performed neonatal somatosensory (SEP), visual (VEP) evoked potentials and electroencephalogram (EEG). The effect of SEP, VEP or EEG abnormalities on Griffith's developmental scales at 12 and 24 months was measured; positive (PPV) and negative (NPV) predictive value, sensitivity, specificity and accuracy were calculated...
April 16, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/29679698/neurophysiological-and-neuroradiological-multimodal-approach-for-early-poor-outcome-prediction-after-cardiac-arrest
#17
Maenia Scarpino, Giovanni Lanzo, Francesco Lolli, Riccardo Carrai, Marco Moretti, Maddalena Spalletti, Morena Cozzolino, Adriano Peris, Aldo Amantini, Antonello Grippo
INTRODUCTION: Prognosticating outcome after cardiac arrest(CA) requires a multimodal approach. However, evidence regarding combinations of methods is limited. We evaluated whether the combination of electroencephalography(EEG), somatosensory evoked potentials(SEPs) and brain computed tomography(CT) could predict poor outcome. METHODS: We screened our database regarding patients successfully resuscitated after CA, for whom EEG, SEPs and brain CT were available within 24 hours...
April 18, 2018: Resuscitation
https://www.readbyqxmd.com/read/29669030/the-efficacy-of-intraoperative-neurophysiological-monitoring-to-detect-postoperative-neurological-deficits-in-transforaminal-lumbar-interbody-fusion-surgery
#18
Joung Heon Kim, Svetlana Lenina, Grace Mosley, Joshua Meaike, Benjamin Tran, Jun S Kim, Samuel K Cho
BACKGROUND: Despite the extensive use of intraoperative neurophysiological monitoring (IONM) in spinal procedures, there is no standard guideline for what types of IONM tests should be monitored during lumbar procedures with instrumentation. Moreover, the efficacy of IONM during transforaminal lumbar interbody fusion (TLIF) surgery in detecting postoperative neurological deficits has not been well described. OBJECTIVE: To analyze waveform changes from individual IONM tests (somatosensory evoked potentials [SSEP], motor evoked potentials [MEP], and electromyography [EMG]) during TLIF and compare the sensitivity and specificity of these tests in order to determine the best combination to detect postoperative neurological deficits...
April 13, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29649608/standalone-cranio-cervical-decompression-is-feasible-in-children-with-mucopolysaccharidosis-type-i-iva-and-vi
#19
Harald Krenzlin, Ta-Chih Tan, Christina Lampe, Christian Lampe, Markus Knuf, Peter Horn, Manfred Schwarz
BACKGROUND CONTEXT: In patients with Mucopolysaccharidosis (MPS), glycosaminoglycans deposits in the dura mater and supporting ligaments cause spinal cord compression and consecutive myelopathy, predominantly of the cranio-cervical junction. Disease characteristics of cranio-cervical stenosis (CCS) in MPS patients differ profoundly from other hereditary and degenerative forms. Due to high peri-procedural morbidity and mortality, MPS patients pose a substantial challenge to the unexperienced medical care provider...
April 9, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29625342/phantom-somatosensory-evoked-potentials-following-selective-intraneural-electrical-stimulation-in-two-amputees
#20
Giuseppe Granata, Riccardo Di Iorio, Roberto Romanello, Francesco Iodice, Stanisa Raspopovic, Francesco Petrini, Ivo Strauss, Giacomo Valle, Thomas Stieglitz, Paul Čvančara, David Andreu, Jean-Louis Divoux, David Giraud, Loic Wauters, Arthur Hiairrassary, Winnie Jensen, Silvestro Micera, Paolo Maria Rossini
OBJECTIVE: The aim of the paper is to objectively demonstrate that amputees implanted with intraneural interfaces are truly able to feel a sensation in the phantom hand by recording "phantom" somatosensory evoked potentials from the corresponding brain areas. METHODS: We implanted four transverse intrafascicular multichannel electrodes, available with percutaneous connections to a multichannel electrical stimulator, in the median and ulnar nerves of two left trans-radial amputees...
March 26, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
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