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Somatosensory Evoked Potentials

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https://www.readbyqxmd.com/read/28912671/brownian-optogenetic-noise-photostimulation-on-the-brain-amplifies-somatosensory-evoked-field-potentials
#1
Nayeli Huidobro, Abraham Mendez-Fernandez, Ignacio Mendez-Balbuena, Ranier Gutierrez, Rumyana Kristeva, Elias Manjarrez
Stochastic resonance (SR) is an inherent and counter-intuitive mechanism of signal-to-noise ratio (SNR) facilitation in biological systems associated with the application of an intermediate level of noise. As a first step to investigate in detail this phenomenon in the somatosensory system, here we examined whether the direct application of noisy light on pyramidal neurons from the mouse-barrel cortex expressing a light-gated channel channelrhodopsin-2 (ChR2) can produce facilitation in somatosensory evoked field potentials...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28865131/quercetin-reduces-neural-tissue-damage-and-promotes-astrocyte-activation-after-spinal-cord-injury-in-rats
#2
Yeyang Wang, Wenjun Li, Mingsen Wang, Chuangxin Lin, Guitao Li, Xiaozhong Zhou, Junnan Luo, Dadi Jin
Spinal cord injury (SCI) is lead to locomotor impairment because of neurological damage after following trauma. Quercetin (Que) has been confirmed have a neuro-protective effect during nerve damage processes. The purpose of this study was to determine the roles of Que in functional recovery, cavity formation, astrocyte activation and nerve regeneration following SCI. Sprague-Dawley rats were randomly divided into 3 groups: Sham group, SCI group and Que + SCI group. A rat model of SCI was made at T10 using the modified Allen's method...
September 2, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28864837/near-infrared-spectroscopy-nirs-and-vagus-somatosensory-evoked-potentials-vsep-in-the-early-diagnosis-of-alzheimer-s-disease-rationale-design-methods-and-first-baseline-data-of-the-vogel-study
#3
Thomas Polak, Martin J Herrmann, Laura D Müller, Julia B M Zeller, Andrea Katzorke, Matthias Fischer, Fabian Spielmann, Erik Weinmann, Leif Hommers, Martin Lauer, Andreas J Fallgatter, Jürgen Deckert
Functional near-infrared spectroscopy (fNIRS) and vagus somatosensory evoked potentials (VSEP) show deviant patterns in subjects with Alzheimer's disease (AD) compared to healthy controls. We now aimed at testing the predictive value of these methods in the early diagnosis of AD. The Vogel study is a prospective, observational, long-term follow-up study with three time points of investigation within 6 years. Residents of the city of Würzburg born between 1936 and 1941 were recruited. Every participant underwent physical, psychiatric, and laboratory examinations, and performed an intense neuropsychological testing as well as VSEP and NIRS according to the published procedures...
September 1, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28863007/intraoperative-neurophysiologic-monitoring-for-prediction-of-postoperative-neurological-improvement-in-a-child-with-chiari-type-i-malformation
#4
Yukari Kawasaki, Susumu Uchida, Kouhei Onishi, Masako Toyokuni, Kazuo Okanari, Minoru Fujiki
INTRODUCTION: Although many surgical treatment strategies for Chiari malformation type I (CM-I) have been reported, the most appropriate surgical technique remains controversial. It is wholly ascribable to the complicacy of pathological condition in CM-I. Recently, intraoperative neurophysiologic monitoring (INM) is becoming prevalent in spinal surgery. Indeed, motor-evoked potentials (MEPs) monitoring and somatosensory-evoked potentials (SSEPs) monitoring are standard tools to minimize the risk of neurologic injury and postoperative deficits...
August 31, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28859916/the-effect-of-type-of-afferent-feedback-timed-with-motor-imagery-on-the-induction-of-cortical-plasticity
#5
N Mrachacz-Kersting, M Voigt, Ajt Stevenson, S Aliakbaryhosseinabadi, N Jiang, K Dremstrup, D Farina
A peripherally generated afferent volley that arrives at the peak negative (PN) phase during the movement related cortical potential (MRCP) induces significant plasticity at the cortical level in healthy individuals and chronic stroke patients. Transferring this type of associative brain-computer interface (BCI) intervention into the clinical setting requires that the proprioceptive input is comparable to the techniques implemented during the rehabilitation process. These consist mainly of functional electrical stimulation (FES) and passive movement induced by an actuated orthosis...
August 28, 2017: Brain Research
https://www.readbyqxmd.com/read/28858781/epidermal-electrode-technology-for-detecting-ultrasonic-perturbation-of-sensory-brain-activity
#6
Stanley Huang, Jonathan A N Fisher, Meijun Ye, Yun-Soung Kim, Rui Ma, Marjan Nabili, Victor Krauthamer, Matthew R Myers, Todd P Coleman, Cristin G Welle
OBJECTIVE: We aim to demonstrate the in vivo capability of a wearable sensor technology to detect localized perturbations of sensory-evoked brain activity. METHODS: Cortical somatosensory evoked potentials (SSEPs) were recorded in mice via wearable, flexible epidermal electrode arrays. We then utilized the sensors to explore the effects of transcranial focused ultrasound, which noninvasively induced neural perturbation. SSEPs recorded with flexible epidermal sensors were quantified and benchmarked against those recorded with invasive epidural electrodes...
August 29, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28842222/physical-performance-and-movement-evoked-pain-profiles-in-community-dwelling-individuals-at-risk-for-knee-osteoarthritis
#7
Yenisel Cruz-Almeida, Josue Cardoso, Joseph L Riley, Burel Goodin, Christopher D King, Megan Petrov, Emily J Bartley, Kimberly T Sibille, Toni L Glover, Matthew S Herbert, Hailey W Bulls, Adriana Addison, Roland Staud, David Redden, Laurence A Bradley, Roger B Fillingim
BACKGROUND: Knee pain associated with osteoarthritis is a significant contributor to decreased physical function. Recent evidence supports the inter-individual heterogeneity associated with knee pain presentation, but whether there is similar heterogeneity in physical performance among these individuals has not been previously examined. The aim of the present study was to characterize the variability in physical performance profiles and the pain evoked by their performance (i.e., movement-evoked pain)...
August 24, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28828401/abnormalities-in-dynamic-brain-activity-caused-by-mild-traumatic-brain-injury-are-partially-rescued-by-the-cannabinoid-type-2-receptor-inverse-agonist-smm-189
#8
Yu Liu, Samuel S McAfee, Natalie M Guley, Nobel Del Mar, Wei Bu, Scott A Heldt, Marcia G Honig, Bob M Moore, Anton Reiner, Detlef H Heck
Mild traumatic brain injury (mTBI) can cause severe long-term cognitive and emotional deficits, including impaired memory, depression, and persevering fear, but the neuropathological basis of these deficits is uncertain. As medial prefrontal cortex (mPFC) and hippocampus play important roles in memory and emotion, we used multi-site, multi-electrode recordings of oscillatory neuronal activity in local field potentials (LFPs) in awake, head-fixed mice to determine if the functioning of these regions was abnormal after mTBI, using a closed-skull focal cranial blast model...
July 2017: ENeuro
https://www.readbyqxmd.com/read/28827155/effects-of-mental-workload-on-involuntary-attention-a-somatosensory-erp-study
#9
Sungchul Mun, Mincheol Whang, Sangin Park, Min-Chul Park
Previous psychophysiological assessments of mental workload have relied on the addition of visual or auditory stimuli. This study investigated the tactile ERP and EEG spectral power correlates of mental workload by relating limited-capacity involuntary attention allocation to changes in late positive potential (LPP) amplitude, alpha, and theta powers. We examined whether mental workload (high-level cognitive control) can be evaluated using somatosensory stimuli. Sixteen participants all performed three tasks of varying difficulty...
August 18, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28822456/-human-umbilical-cord-mesenchymal-stem-cell-transplantation-for-the-treatment-of-two-noncontinuous-segments-spinal-cord-compression-injury-in-rabbits
#10
C H Yang, B Q Yu, Q H You, J J Feng
Objective: In order to explore the effects of human umbilical cord mesenchymal stem cells (UCMSC) transplantation on the treatment of two noncontinuous segments spinal cord compression injury and to investigate whether repeated intravenous injection UCMSC was more beneficial for the recovery of spinal cord function. Methods: A total of 30 adult rabbits were randomly divided into three groups: control group (received PBS), single injection group, repeated injection group with 3 days intervals. A noncontinuous two segments SCI model was established by using the 2F Fogarty balloon catheter...
August 8, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28819259/dendritic-calcium-spikes-are-clearly-detectable-at-the-cortical-surface
#11
Mototaka Suzuki, Matthew E Larkum
Cortical surface recording techniques such as EEG and ECoG are widely used for measuring brain activity. The prevailing assumption is that surface potentials primarily reflect synaptic activity, although non-synaptic events may also contribute. Here we show that dendritic calcium spikes occurring in pyramidal neurons (that we showed previously are cognitively relevant) are clearly detectable in cortical surface potentials. To show this we developed an optogenetic, non-synaptic approach to evoke dendritic calcium spikes in vivo...
August 17, 2017: Nature Communications
https://www.readbyqxmd.com/read/28813949/monitoring-brain-potentials-to-guide-neurorehabilitation-of-tracking-impairments
#12
Boris Yazmir, Miriam Reiner
Motor impairments come in different forms. One class of motor impairments, relates to accuracy of tracking a moving object, as, for instance, when chasing in an attempt to catch it. Here we look at neural signals associated with errors in tracking, and the implications for brain-computer-interfaces that target impairment-tailored rehabilitation. As a starting point, we characterized EEG signals evoked by tracking errors during continuous natural motion, in healthy participants. Participants played a virtual 3D, ecologically valid haptic tennis game, and had to track a moving tennis ball in order to hit and send the ball towards the opponent's court...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28807846/the-reliability-of-commonly-used-electrophysiology-measures
#13
K E Brown, K R Lohse, I M S Mayer, G Strigaro, M Desikan, E P Casula, S Meunier, T Popa, J-C Lamy, O Odish, B R Leavitt, A Durr, R A C Roos, S J Tabrizi, J C Rothwell, L A Boyd, M Orth
BACKGROUND: Electrophysiological measures can help understand brain function both in healthy individuals and in the context of a disease. Given the amount of information that can be extracted from these measures and their frequent use, it is essential to know more about their inherent reliability. OBJECTIVE/HYPOTHESIS: To understand the reliability of electrophysiology measures in healthy individuals. We hypothesized that measures of threshold and latency would be the most reliable and least susceptible to methodological differences between study sites...
July 31, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28805756/-an-experience-of-neurophysiological-monitoring-in-neurosurgery
#14
A G Vasyatkina, E A Levin, K Yu Orlov, V V Kobozev
AIM: To evaluate the efficacy of neuromonitoring methods in prevention of postoperative neurological complications and estimation of predictive power of intraoperative changes in monitored characteristics. MATERIAL AND METHODS: Retrospective study examined 240 patients, operated in the years 2014-2015 using intraoperative neurophysiological monitoring. One hundred and seventy-three patients suffered from hemispheric lesions and 67 had lesions located in or near the brainstem...
2017: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/28803174/intraoperative-vascular-neuromonitoring-in-patients-with-subarachnoid-hemorrhage-a-pilot-study-using-combined-laser-doppler-spectrophotometry
#15
Emilija Schmitz, Barbara Bischoff, Dennis Wolf, Hubert Schmitt, Ilker Y Eyupoglu, Karl Roessler, Michael Buchfelder, Björn Sommer
OBJECTIVE: Intraoperative monitoring of cerebral microcirculation in patients with subarachnoid hemorrhage (SAH) may predict the postoperative neurological outcome. In this pilot study, we examined the value of a novel non-invasive real-time measurement technique to detect changes in local microcirculation. METHODS: We used the laser-Doppler spectrophotometry system "Oxygen-to-see(O2C)" in 14 patients with SAH Hunt & Hess grade 2 to 5, who underwent microsurgical clipping of cerebral aneurysms...
August 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28780535/clinical-physiological-and-pathological-characterisation-of-the-sensory-predominant-peripheral-neuropathy-in-copper-deficiency
#16
Sean W Taylor, Ruple S Laughlin, Neeraj Kumar, Brent Goodman, Christopher J Klein, Peter J Dyck, P James B Dyck
INTRODUCTION: Myelopathy is considered the most common neurological complication of copper deficiency. Concurrent peripheral neuropathy has been recognised in association with copper deficiency but has not been well characterised. OBJECTIVES: To characterise the clinical, physiological and pathological features of copper-deficient peripheral neuropathy. METHODS: Patients with simultaneous copper deficiency (<0.78 μg/mL) and peripheral neuropathy seen at the Mayo Clinic from 1985 to 2005 were identified...
August 5, 2017: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/28780193/is-brain-computed-tomography-combined-with-somatosensory-evoked-potentials-useful-in-the-prediction-of-brain-death-after-cardiac-arrest
#17
Maenia Scarpino, Giovanni Lanzo, Francesco Lolli, Marco Moretti, Riccardo Carrai, Maria Luisa Migliaccio, Maddalena Spalletti, Manuela Bonizzoli, Adriano Peris, Aldo Amantini, Antonello Grippo
BACKGROUND: Brain death (BD) in coma after cardiac arrest (CA) is difficult to predict. Basal ganglia gray matter/white matter (GM/WM) ratio density and somatosensory evoked potentials (SEPs) may differentiate patients evolving toward BD. METHODS: We used SEPs and brain computed tomography (CT) after coma onset, within the first 24hours. RESULTS: Of the 160 patients included in the study, 22 (14%) evolved toward BD. SEP patterns predicted BD (ROC area=0...
August 2, 2017: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/28770112/anodal-transcranial-direct-current-stimulation-provokes-neuroplasticity-in-repetitive-mild-traumatic-brain-injury-in-rats
#18
Ho Jeong Kim, Soo Jeong Han
Repetitive mild traumatic brain injury (rmTBI) provokes behavioral and cognitive changes. But the study about electrophysiologic findings and managements of rmTBI is limited. In this study, we investigate the effects of anodal transcranial direct current stimulation (tDCS) on rmTBI. Thirty-one Sprague Dawley rats were divided into the following groups: sham, rmTBI, and rmTBI treated by tDCS. Animals received closed head mTBI three consecutive times a day. Anodal tDCS was applied to the left motor cortex. We evaluated the motor-evoked potential (MEP) and the somatosensory-evoked potential (SEP)...
2017: Neural Plasticity
https://www.readbyqxmd.com/read/28769749/attention-in-and-out-scalp-level-and-intracranial-eeg-correlates-of-interoception-and-exteroception
#19
Indira García-Cordero, Sol Esteves, Ezequiel P Mikulan, Eugenia Hesse, Fabricio H Baglivo, Walter Silva, María Del Carmen García, Esteban Vaucheret, Carlos Ciraolo, Hernando S García, Federico Adolfi, Marcos Pietto, Eduar Herrera, Agustina Legaz, Facundo Manes, Adolfo M García, Mariano Sigman, Tristán A Bekinschtein, Agustín Ibáñez, Lucas Sedeño
Interoception, the monitoring of visceral signals, is often presumed to engage attentional mechanisms specifically devoted to inner bodily sensing. In fact, most standardized interoceptive tasks require directing attention to internal signals. However, most studies in the field have failed to compare attentional modulations between internally- and externally-driven processes, thus probing blind to the specificity of the former. Here we address this issue through a multidimensional approach combining behavioral measures, analyses of event-related potentials and functional connectivity via high-density electroencephalography, and intracranial recordings...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28760352/image-guided-percutaneous-intralesional-administration-of-mesenchymal-stromal-cells-in-subjects-with-chronic-complete-spinal-cord-injury-a-pilot-study
#20
Ticiana Ferreira Larocca, Carolina Thé Macêdo, Bruno Solano de Freitas Souza, Yuri M Andrade-Souza, Cristiane Flora Villarreal, André Costa Matos, Daniela Nascimento Silva, Kátia Nunes da Silva, Clarissa Lima E Moura de Souza, Daniela da Silva Paixão, Milena da Rocha Bezerra, Rodrigo Leal Alves, Milena Botelho Pereira Soares, Ricardo Ribeiro Dos Santos
BACKGROUND AIMS: The potential of cell therapies to improve neurological function in subjects with spinal cord injury (SCI) is currently under investigation. In this context, the choice of cell type, dose, route and administration regimen are key factors. Mesenchymal stromal cells (MSCs) can be easily obtained, expanded and are suitable for autologous transplantation. Here we conducted a pilot study that evaluated safety, feasibility and potential efficacy of intralesional MSCs transplantation performed through image-guided percutaneous injection, in subjects with chronic complete SCI...
July 28, 2017: Cytotherapy
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