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decompression sickness

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https://www.readbyqxmd.com/read/28439981/evolution-of-the-plasma-proteome-of-divers-before-and-after-a-single-scuba-dive
#1
Jacky Lautridou, Vianney Pichereau, Sébastien Artigaud, Benoit Bernay, Otto Barak, Ryan Hoiland, Andrew T Lovering, Ingrid Eftedal, Zeljko Dujic, François Guerrero
PURPOSE: Decompression sickness (DCS) is a poorly understood and complex systemic disease caused by inadequate desaturation following a reduction of ambient pressure. A previous proteomic study of ours showed that DCS occurrence but not diving was associated with changes in the plasma proteome in rats, including a dramatic decrease of abundance of the tetrameric form of Transthyretin (TTR). The present study aims to assess the impact on the human blood proteome of a dive inducing significant decompression stress but without inducing DCS symptoms...
April 25, 2017: Proteomics. Clinical Applications
https://www.readbyqxmd.com/read/28415099/p594contrast-transthoracic-echocardiography-as-a-gatekeeper-for-patent-foramen-ovale-closure
#2
M Muratori, G Italiano, E Innocenti, L Fusini, M Mapelli, G Tamborini, S Ghulam Ali, P Gripari, A Maltagliati, F Celeste, M Pepi
Background.: The presence of patent foramen ovale (PFO) has been linked to many illness, including cryptogenic stroke, transient ischemic attack, migraine, platypnea-orthodeoxia syndrome and decompression sickness in scuba divers. Transesophageal echocardiography is the gold standard technique for the visualization of atrial septal anatomy, but it is a secondary level exam, not always available, with additional associated costs and not completely free from procedural risks. Standard transthoracic echocardiography (TTE) has a too low sensitivity for PFO screening...
December 1, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28411929/updates-in-decompression-illness
#3
REVIEW
Neal W Pollock, Dominique Buteau
Decompression sickness and arterial gas embolism, collectively known as decompression illness (DCI), are rare but serious afflictions that can result from compressed gas diving exposures. Risk is primarily determined by the pressure-time profile but is influenced by several factors. DCI can present idiosyncratically but with a wide range of neurologic symptoms. Examination is critical for assessment in the absence of diagnostic indicators. Many conditions must be considered in the differential diagnosis. High-fraction oxygen breathing provides first aid but definitive treatment of DCI is hyperbaric oxygen...
May 2017: Emergency Medicine Clinics of North America
https://www.readbyqxmd.com/read/28378268/carbon-dioxide-poisoning-a-literature-review-of-an-often-forgotten-cause-of-intoxication-in-the-emergency-department
#4
REVIEW
Kris Permentier, Steven Vercammen, Sylvia Soetaert, Christian Schellemans
The goal of this article was to provide an overview of the literature available on carbon dioxide intoxication. Articles were included based on their focus on medical or physiological effects of carbon dioxide. Studies related to decompression sickness were excluded. Mechanisms of carbon dioxide poising (both as an asphyxiant and as a toxicant) were described. Our review suggested that precautions are needed when handling dry ice or while working in confined spaces. Pre-hospital responders also need to pay attention for the possible diagnosis of CO2 intoxication for their own safety...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28357838/female-professional-divers-similarities-and-differences-between-male-and-female-professional-divers
#5
Ågot Irgens, Kari Troland, Marit Grønning
BACKGROUND: The aim of the present study was to explore the potential differences between female and male professional divers with regards to demographics, diving certificates, areas of diving, diving activity and health effects. MATERIALS AND METHODS: The Norwegian Labour Inspection Authority's Diving certificate register contains data on all professional inshore divers who have held a certificate at any time since 1980. Forty nine per cent of these divers responded to the "Norwegian diver 2011" questionnaire...
2017: International Maritime Health
https://www.readbyqxmd.com/read/28357820/preventive-effect-of-rosiglitazone-on-liver-injury-in-a-mouse-model-of-decompression-sickness
#6
Bin Peng, Miao-Miao Chen, Zheng-Lin Jiang, Xia Li, Guo-Hua Wang, Li-Hua Xu
BACKGROUND AND AIMS: Severe decompression sickness (DCS) is a multi-organ injury. This study investigated the preventive effects of rosiglitazone on liver injury following rapid decompression in mice and examined the underlying mechanisms. METHODS: Mice were randomly divided into four groups: a control group, vehicle group, and rosiglitazone (5 and 10 mg·kg⁻¹) groups, the latter three being exposed to a pressure of 911 kPa. Haematoxylin and eosin staining, plasma levels of alanine transaminase (ALT), aspartate transaminase (AST) and lactate dehydrogenase and blood cell counts were used to evaluate liver injury at 30 min after rapid decompression...
March 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28357819/a-comparative-evaluation-of-two-decompression-procedures-for-technical-diving-using-inflammatory-responses-compartmental-versus-ratio-deco
#7
Enzo Spisni, Claudio Marabotti, Luigia De Fazio, Maria Chiara Valerii, Elena Cavazza, Stefano Brambilla, Klarida Hoxha, Antonio L'Abbate, Pasquale Longobardi
INTRODUCTION: The aim of this study was to compare two decompression procedures commonly adopted by technical divers: the ZH-L16 algorithm modified by 30/85 gradient factors (compartmental decompression model, CDM) versus the 'ratio decompression strategy' (RDS). The comparison was based on an analysis of changes in diver circulating inflammatory profiles caused by decompression from a single dive. METHODS: Fifty-one technical divers performed a single trimix dive to 50 metres' sea water (msw) for 25 minutes followed by enriched air (EAN50) and oxygen decompression...
March 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28336821/hyperbaric-oxygen-therapy-reduces-renal-lactate-production
#8
Thomas S Nørlinger, Per Mose Nielsen, Haiyun Qi, Emmeli Mikkelsen, Kasper Hansen, Nikolaj H Schmidt, Michael Pedersen, Peter Agger, Fredrik Palm, Christoffer Laustsen
Intrarenal hypoxia is an acknowledged factor contributing to the development of diabetic nephropathy. Hyperbaric oxygen (HBO) therapy is a well-known adjuvant treatment for several medical conditions, such as decompression sickness, infections, and wound healing. The underlying metabolic response of HBO is largely unknown. In this study, we investigated the effect of HBO on the intrarenal metabolic alteration in diabetes. Hyperpolarized [1-(13)C]pyruvate MRI was performed to assess intrarenal energy metabolism in normoglycemic controls and short-term (2 weeks) streptozotocin-induced diabetic rats with and without HBO for five consecutive days...
March 2017: Physiological Reports
https://www.readbyqxmd.com/read/28296928/the-probability-and-severity-of-decompression-sickness
#9
Laurens E Howle, Paul W Weber, Ethan A Hada, Richard D Vann, Petar J Denoble
Decompression sickness (DCS), which is caused by inert gas bubbles in tissues, is an injury of concern for scuba divers, compressed air workers, astronauts, and aviators. Case reports for 3322 air and N2-O2 dives, resulting in 190 DCS events, were retrospectively analyzed and the outcomes were scored as (1) serious neurological, (2) cardiopulmonary, (3) mild neurological, (4) pain, (5) lymphatic or skin, and (6) constitutional or nonspecific manifestations. Following standard U.S. Navy medical definitions, the data were grouped into mild-Type I (manifestations 4-6)-and serious-Type II (manifestations 1-3)...
2017: PloS One
https://www.readbyqxmd.com/read/28251616/migraine-with-neurological-features-in-a-scuba-diver-with-a-patent-foramen-ovale
#10
Ashhar Ali, A David Rothner
Neurologic complications of decompression sickness have been observed for over half of a century. Little is known, however, about the risk of diving in patients that suffer from migraine with aura (MWA). We report the case of a pediatric patient with a history of migraine with aura, who was later found to have a PFO, who developed headache with neurological symptoms during a scuba diving lesson.
April 2017: Headache
https://www.readbyqxmd.com/read/28221393/comex-30-f%C3%A3-r-behandling-av-tryckfallssjuka-med-neurologiska-symtom
#11
Anders Rosén, Nicklas Oscarsson, Olaf Gräbel, Göran Sandström
The use of treatment table COMEX 30 for severe neurological decompression sickness Decompression sickness (DCS) can occur after all dives. It often requires treatment in a pressure chamber. DCS with symptoms from the nervous system is particularly serious. In certain cases, the commonly used recompression table (USN TT6) does not suffice to revert severe neurological symptoms. A more advanced recompression table, COMEX 30, can be utilized in these cases. We report three cases of DCS where treatment according to COMEX 30 successfully resolved neurological symptoms...
February 17, 2017: Läkartidningen
https://www.readbyqxmd.com/read/28217293/application-of-hyperbaric-oxygen-in-liver-transplantation
#12
REVIEW
Hu Lv, Cui-Hong Han, Xue-Jun Sun, Wen-Wu Liu
In recent years, hyperbaric oxygen (HBO) has been used in the treatment of a lot of diseases such as decompression sickness, arterial gas embolism, carbon dioxide poisoning, soft tissue infection, refractory osteomyelitis, and problematic wound, but little is known about its application in liver transplantation. Although several studies have been conducted to investigate the protective effects of HBO on liver transplantation and liver preservation, there are still some controversies on this issue, especially its immunomodulatory effect...
October 2016: Medical Gas Research
https://www.readbyqxmd.com/read/28159488/lateral-lumbar-retroperitoneal-transpsoas-approach-in-the-setting-of-spondylodiscitis-a-technical-note
#13
George M Ghobrial, Fadi Al-Saiegh, Daniel Franco, Daniel Benito, Joshua Heller
Thoracolumbar spondylodiscitis is a morbid disease entity, impacting a sick patient population with multiple comorbidities. Wherever possible, surgical measures in this population should limit the extent of soft tissue disruption and overall morbidity that is often associated with anteroposterior thoracolumbar decompression and fusion. The authors describe the rationale, technique, and use of the lateral lumbar transpsoas retroperitoneal approach in tandem with posterior decompression and instrumented fusion in the treatment of circumferential thoracolumbar spondylodiscitis with or without epidural abscesses...
January 31, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28150725/allometric-scaling-of-decompression-sickness-risk-in-terrestrial-mammals-cardiac-output-explains-risk-of-decompression-sickness
#14
Andreas Fahlman
A probabilistic model was used to predict decompression sickness (DCS) outcome in pig (70 and 20 kg), hamster (100 g), rat (220 g) and mouse (20 g) following air saturation dives. The data set included 179 pig, 200 hamster, 360 rat, and 224 mouse exposures to saturation pressures ranging from 1.9-15.2 ATA and with varying decompression rates (0.9-156 ATA • min(-1)). Single exponential kinetics described the tissue partial pressures (Ptiss) of N2: Ptiss =  ∫(Pamb - Ptiss) • τ(-1) dt, where Pamb is ambient N2 pressure and τ is a time constant...
February 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28119191/bayesian-approach-to-decompression-sickness-model-parameter-estimation
#15
L E Howle, P W Weber, J M Nichols
We examine both maximum likelihood and Bayesian approaches for estimating probabilistic decompression sickness model parameters. Maximum likelihood estimation treats parameters as fixed values and determines the best estimate through repeated trials, whereas the Bayesian approach treats parameters as random variables and determines the parameter probability distributions. We would ultimately like to know the probability that a parameter lies in a certain range rather than simply make statements about the repeatability of our estimator...
March 1, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28114372/bubble-induced-endothelial-microparticles-promote-endothelial-dysfunction
#16
Xuhua Yu, Jiajun Xu, Guoyang Huang, Kun Zhang, Long Qing, Wenwu Liu, Weigang Xu
Decompression sickness is a systemic pathophysiological process caused by bubbles and endothelial microparticles (EMPs) are established markers reflecting competency of endothelial function and vascular biology. Here, we investigated the effects of bubble-induced EMPs on endothelial cells in vitro and vivo. Rat pulmonary microvascular endothelial cells (PMVECs) were isolated and stimulated by bubbles and bubble-induced EMPs were collected and incubated with normal PMVECs in vitro. Cell viability and apoptosis were detected using Cell Counting Kit-8 assay and Annexin V FITC/PI double staining, respectively...
2017: PloS One
https://www.readbyqxmd.com/read/28112272/endothelia-targeting-protection-by-escin-in-decompression-sickness-rats
#17
Kun Zhang, Zhongxin Jiang, Xiaowei Ning, Xuhua Yu, Jiajun Xu, Peter Buzzacott, Weigang Xu
Endothelial dysfunction is involved in the pathogenesis of decompression sickness (DCS) and contributes substantively to subsequent inflammatory responses. Escin, the main active compound in horse chestnut seed extract, is well known for its endothelial protection and anti-inflammatory properties. This study aimed to investigate the potential protection of escin against DCS in rats. Escin was administered orally to adult male rats for 7 d (1.8 mg/kg/day) before a simulated air dive. After decompression, signs of DCS were monitored, and blood and pulmonary tissue were sampled for the detection of endothelia related indices...
January 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28103732/evaluation-of-antivenom-therapy-for-vipera-palaestinae-bites-in-children-experience-of-two-large-tertiary-care-pediatric-hospitals
#18
Dikla Pivko-Levy, Itamar Munchnak, Ayelet Rimon, Uri Balla, Dennis Scolnik, Christopher Hoyte, Yair Voliovitch, Miguel Glatstein
BACKGROUND: Antivenom has been successfully used to treat systemic and progressive, local manifestations of envenomation inflicted by Vipera (V.) palaestinae, the most common venomous snake in Israel. The objective of this study was to evaluate the fixed dose V. palaestinae monovalent (equine) immunoglobulin G antivenom used in two pediatric emergency departments. In particular, we wanted to assess the need for repeated antivenom administration and the rate of adverse antivenom effects in children...
April 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28095955/preconditioning-to-reduce-decompression-stress-in-scuba-divers
#19
Peter Germonpré, Costantino Balestra
BACKGROUND: Using ultrasound imaging, vascular gas emboli (VGE) are observed after asymptomatic scuba dives and are considered a key element in the potential development of decompression sickness (DCS). Diving is also accompanied with vascular dysfunction, as measured by flow-mediated dilation (FMD). Previous studies showed significant intersubject variability to VGE for the same diving exposure and demonstrated that VGE can be reduced with even a single pre-dive intervention. Several preconditioning methods have been reported recently, seemingly acting either on VGE quantity or on endothelial inflammatory markers...
February 1, 2017: Aerospace Medicine and Human Performance
https://www.readbyqxmd.com/read/28009387/diving-exposure-and-health-effects-in-divers-working-in-different-areas-of-professional-diving
#20
Ågot Irgens, Kari Troland, Rune Djurhuus, Marit Grønning
BACKGROUND: The aim of the present study was to compare diving exposure and health effects in different areas of professional diving. MATERIALS AND METHODS: The Norwegian Labour Inspection Authority's Diving Register contains data on all professional inshore divers who have held a diving certificate at any time since 1980. Of these divers, the "Norwegian diver 2011" questionnaire was completed by 2848 (48.7%). A total of 1167 male divers reported that they often worked in one area of diving only (rescue diving, diving instruction, fish farming, quay/construction work and offshore/oil related)...
2016: International Maritime Health
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