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Chronic pain units

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https://www.readbyqxmd.com/read/29028748/problematic-use-of-prescribed-opioids-for-chronic-noncancer-pain-no-scarcity-of-data-outside-the-united-states
#1
Winfried Häuser, Thomas Tölle
No abstract text is available yet for this article.
November 2017: Pain
https://www.readbyqxmd.com/read/29025534/-endovascular-treatment-of-a-gastroduodenal-artery-pseudoaneurysm-rupture-after-a-car-accident
#2
Sofia Dutra, Filipe Veloso Gomes, Tiago Bilhim, Élia Coimbra
The authors present a case of a 39-year-old man with alcoholic chronic pancreatitis that was admitted in the emergency department after a car accident, complaining of abdominal pain and looking pale. The patient was hemodinamically unstable, requiring blood transfusions. He underwent computed tomography angiogram of the abdomen and pelvis, showing a pseudoaneurysm of the gastroduodenal artery and a hemoperitoneum. He was referred to our interventional radiology unit and submitted to endovascular treatment, consisting of 'backdoor' and 'frontdoor' embolization of the gastroduodenal artery and pseudoaneurysm neck with coils, with total exclusion in control angiography...
September 29, 2017: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/29025157/chronic-pain-after-traumatic-brain-injury-pathophysiology-and-pain-mechanisms
#3
Karen-Amanda Irvine, J David Clark
Background: Traumatic brain injury refers to a broad range of neurological, cognitive, and emotional factors that result from the application of an external force to the head. Individuals recovering from traumatic brain injury will frequently experience acute and chronic pain. Objective: The objective of this paper is to discuss the pathophysiological changes resulting from traumatic brain injury and how these may be involved in the development and persistence of pain after injury...
August 29, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29016551/pectoral-fascial-pecs-i-and-ii-blocks-as-rescue-analgesia-in-a-patient-undergoing-minimally-invasive-cardiac-surgery
#4
Suraj Yalamuri, Rebecca Y Klinger, W Michael Bullock, Donald D Glower, Brandi A Bottiger, Jeffrey C Gadsden
INTRODUCTION: Patients undergoing minimally invasive cardiac surgery have the potential for significant pain from the thoracotomy site. We report the successful use of pectoral nerve block types I and II (Pecs I and II) as rescue analgesia in a patient undergoing minimally invasive mitral valve repair. CASE REPORT: In this case, a 78-year-old man, with no history of chronic pain, underwent mitral valve repair via right anterior thoracotomy for severe mitral regurgitation...
October 6, 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29016408/family-initiated-pediatric-rapid-response-characteristics-impetus-and-outcomes
#5
Aarti C Bavare, Jenilea K Thomas, Elizabeth P Elliott, Angela C Morgan, Jeanine M Graf
BRIEF DESCRIPTION: Family-initiated rapid response (FIRR) empowers families to express concern and seek care from specialized response teams. We studied FIRRs that occurred in a pediatric tertiary hospital over a 3-year period. The main aims were to describe the characteristics and outcomes of FIRRs and compare them with clinician-activated RRs (C-RRs). Of the 1,906 RRs events reviewed, 49 (2.6%) were FIRRs. All FIRRs had appropriate clinical triggers with the most common being uncontrolled pain...
October 6, 2017: Journal for Healthcare Quality: Official Publication of the National Association for Healthcare Quality
https://www.readbyqxmd.com/read/28992838/-sparse-knowledge-about-patient-reported-outcomes-after-major-emergency-abdominal-surgery
#6
EDITORIAL
Jakob Ohm Oreskov, Sarah Ekeløf, Jakob Burcharth, Ismail Gøgenur
Little is known about patient-reported outcomes after major emergency abdominal surgery. Studies on patients undergoing major elective abdominal surgery and patients in the intensive care unit report significant challenges with chronic pain, functional impairment, quality of life, depression and post-traumatic stress disorder (PTSD). Approximately one out of three patients experience chronic pain and functional impairment after major emergency abdominal surgery. The magnitude of depression and PTSD after major emergency abdominal surgery have not been studied before...
October 9, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28982637/pediatric-chronic-patients-at-outpatient-clinics-a-study-in-a-latin-american-university-hospital
#7
Renata A Alveno, Caroline V Miranda, Caroline G Passone, Aurora R Waetge, Elza S Hojo, Sylvia C L Farhat, Vicente Odone-Filho, Uenis Tannuri, Werther B Carvalho, Magda Carneiro-Sampaio, Clovis A Silva
OBJECTIVE: To describe the characteristics of children and adolescentes with chronic diseases of outpatient clinics at a tertiary university hospital. METHODS: A cross-sectional study was performed with 16,237 patients with chronic diseases followed-up in one year. The data were collected through the electronic system, according to the number of physician appointments in 23 pediatric specialties. Patients were divided in two groups: children (0-9 years) and adolescents (10-19 years)...
October 2, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28977113/primary-sclerosing-cholangitis-in-children-and-adolescents
#8
Eleonora Druve Tavares Fagundes, Alexandre Rodrigues Ferreira, Caroline Caldeira Hosken, Thaís Costa Nascentes Queiroz
BACKGROUND: Primary sclerosing cholangitis is a rare disease, but its prevalence has been underestimated in children and adolescents due to broad variation in clinical presentation as well as diagnostic challenges in this life period. OBJECTIVE: To evaluate children and adolescents with primary sclerosing cholangitis and to describe their clinical, laboratorial, histopathological, and cholangiography conditions. METHODS: This is an observational descriptive research that took place from 2005 to 2016 and included all the patients seen in the Outpatient Unit for Pediatric Hepatology of Hospital das Clinicas of UFMG who had been diagnosed with primary sclerosing cholangitis before the age of 18...
October 2, 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28976172/use-of-venoactive-drugs-after-surgery-for-varicose-veins-a-preliminary-study
#9
Daniela Mazzaccaro, Lorenzo Muzzarelli, Alfredo Modafferi, Paolo C Righini, Alberto M Settembrini, Giovanni Nano
BACKGROUND: To assess the use of VenoActive Drugs (VADs) after surgery for chronic venous disease in our Operative Unit in terms of patients' compliance to the therapy and a possible effect on the postoperative pain and QoL. METHODS: Data of consecutive patients who underwent surgery were retrospectively analyzed. All patients, through telephone interview 90 days after the operation, were asked about taking the VAD (either sulodexide or MPFF) which was recommended during the postoperative period...
October 2, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28973845/mesalamine-5-asa-for-the-prevention-of-recurrent-diverticulitis
#10
REVIEW
Flloyd Carter, Majd Alsayb, John K Marshall, Yuhong Yuan
BACKGROUND: Diverticular disease is a common condition that increases in prevalence with age. Recent theories on the pathogenesis of diverticular inflammation have implicated chronic inflammation similar to that seen in ulcerative colitis. Mesalamine, or 5-aminosalicylic acid (5-ASA), is a mainstay of therapy for individuals with ulcerative colitis. Accordingly, 5-ASA has been studied for prevention of recurrent diverticulitis. OBJECTIVES: To evaluate the efficacy of mesalamine (5-ASA) for prevention of recurrent diverticulitis...
October 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28972120/fremanezumab-a-humanized-monoclonal-anti-cgrp-antibody-inhibits-thinly-myelinated-a%C3%AE-but-not-unmyelinated-c-meningeal-nociceptors
#11
Agustin Melo-Carrillo, Andrew M Strassman, Rony-Reuven Nir, Aaron Schain, Rodrigo Noseda, Jennifer Stratton, Rami Burstein
Calcitonin gene-related peptide (CGRP), the most abundant neuropeptide in primary afferent sensory neurons, is strongly implicated in the pathophysiology of migraine headache, but its role in migraine is still equivocal. As a new approach to migraine treatment, humanized anti-CGRP monoclonal antibodies (CGRP-mAb) were developed to reduce the availability of CGRP, and were found effective in reducing the frequency of chronic and episodic migraine. We recently tested the effect of fremanezumab (TEV-48125), a CGRP-mAb, on the activity of second-order trigeminovascular dorsal horn neurons that receive peripheral input from the cranial dura, and found a selective inhibition of high-threshold but not wide-dynamic range class of neurons...
September 29, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28971220/lower-urinary-tract-symptoms-that-predict-microscopic-pyuria
#12
Rajvinder Khasriya, William Barcella, Maria De Iorio, Sheela Swamy, Kiren Gill, Anthony Kupelian, James Malone-Lee
INTRODUCTION AND HYPOTHESIS: Urinary dipsticks and culture analyses of a mid-stream urine specimen (MSU) at 10(5) cfu ml(-1) of a known urinary pathogen are considered the gold standard investigations for diagnosing urinary tract infection (UTI). However, the reliability of these tests has been much criticised and they may mislead. It is now widely accepted that pyuria (≥1 WBC μl(-1)) detected by microscopy of a fresh unspun, unstained specimen of urine is the best biological indicator of UTI available...
October 2, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28968341/differential-effect-of-motor-cortex-stimulation-on-unit-activities-in-the-ventral-posterior-lateral-thalamus-in-cats
#13
Sandra Kobaïter-Maarrawi, Joseph Maarrawi, Nayef Saadé, Luis Garcia-Larrea, Michel Magnin
Although motor cortex stimulation (MCS) is being increasingly used to treat chronic refractory neuropathic pain in humans, its mechanisms of action remain elusive. Studies in animals have suggested the involvement of subcortical structures, in particular the thalamus. Most of these studies have been carried out in rats, a species presenting significant differences in thalamic anatomy and function relative to primates, in particular a very limited number of thalamic GABA interneurons. The aim of this study was to investigate the effects of MCS on single-unit activities of the thalamic ventral posterior lateral (VPL) nucleus in cats, which contains substantial numbers of GABA interneurons...
September 29, 2017: Pain
https://www.readbyqxmd.com/read/28968191/the-genetics-of-pain-implications-for-therapeutics
#14
Jane E Sexton, James J Cox, Jing Zhao, John N Wood
Pain is an increasing clinical challenge affecting about half the population, with a substantial number of people suffering daily intense pain. Such suffering can be linked to the dramatic rise in opioid use and associated deaths in the United States. There is a pressing need for new analgesics with limited side effects. Here, we summarize what we know about the genetics of pain and implications for drug development. We make the case that chronic pain is not one but a set of disease states, with peripheral drive a key element in most...
October 2, 2017: Annual Review of Pharmacology and Toxicology
https://www.readbyqxmd.com/read/28967360/what-can-we-learn-from-osteoarthritis-pain-in-companion-animals
#15
REVIEW
Dorothy Cimino Brown
The lack of successful translation of basic research discoveries into safe and effective treatments for chronic pain patients has led to increased scrutiny of the preclinical models used in pain research, particularly for osteoarthritis, where there is a significant disconnect between the animal models used to study the structural versus symptomatic aspects of the disease. Companion dogs offer a unique opportunity to assess osteoarthritis pain in a physiologically relevant 'model' of the disease. Approximately 20% of the canine pet population spontaneously develops osteoarthritis, translating to at least 15 million dogs in the United States alone...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28966469/usefulness-of-nuclear-whole-body-bone-scanning-for-diagnosis-of-leprosy
#16
Hector Marquez, Joseph McDevitt, Orhan K Öz, Jason Wachsmann
Leprosy, or Hansen's disease, is rare in the United States. Given its rarity, as well as the pathognomonic dermatologic findings, there are few cases in which nuclear medicine imaging plays a role in the diagnostic workup. We present a 39-year-old man who presented with chronic abdominal pain, skin ulcers, and hypercalcemia who underwent computed tomography of the chest and a whole-body bone scan to evaluate for possible underlying neoplasm due to his profound hypercalcemia. Although the diagnosis of leprosy had been established by lower-extremity skin biopsy upon admission, workup for other potential concurrent etiologies of hypercalcemia was performed before initiating therapy...
October 2017: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/28965648/nurse-practitioner-led-pain-management-the-day-after-caesarean-section-a-randomised-controlled-trial-and-follow-up-study
#17
Anthony Schoenwald, Carol Windsor, Edward Gosden, Clint Douglas
BACKGROUND: Pain on the day after caesarean section is often treated with controlled-release oxycodone to supplement the decline in analgesia from intrathecal opioids. Evidence suggests that caesarean birth is a biopsychosocial experience where a comprehensive approach is needed that promotes control and participation in pain management. OBJECTIVES: This study compared immediate-release oxycodone integrated with supportive educational strategies to controlled-release oxycodone...
September 1, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28957835/the-cali-9-a-brief-measure-for-assessing-activity-limitations-in-children-and-adolescents-with-chronic-pain
#18
Amy Lewandowski Holley, Chuan Zhou, Anna C Wilson, Keri Hainsworth, Tonya M Palermo
Pain-related functional limitations represent an important outcome domain to assess in children and adolescents with chronic pain. The aim of this study was to extend the empirical support of the 21-item Child Activity Limitations Interview (CALI-21), a well-validated measure of activity limitations, using a large, multisite sample and to develop a brief form of the measure with more interpretable scoring. A sample of 1616 youth and 1614 parents completed the CALI-21 at an initial appointment in 1 of 3 pain specialty clinics in the Midwest or Northwest United States, or as part of a research study after this initial visit...
September 18, 2017: Pain
https://www.readbyqxmd.com/read/28955475/single-pedicle-hinge-flap-performed-by-shelter-medicine-team-resolves-chronic-antebrachial-wound-in-a-cat
#19
Jodi M Richardson, Jacob M Shivley, Philip A Bushby
CASE SUMMARY: An approximately 3-year-old, male domestic longhair cat was presented to a mobile veterinary unit for routine neuter. Preoperative physical examination revealed an approximately 5 cm × 2 cm scab on the craniolateral portion of the left antebrachium. The cat was anesthetized for the neuter using an injectable anesthesia protocol. After castration, the wound area on the antebrachium was clipped, copiously lavaged and the wound edges were surgically debrided. Injectable antibiotics and analgesic management were instituted...
July 2017: JFMS open reports
https://www.readbyqxmd.com/read/28953954/epidemiological-clinical-diagnostic-and-economic-features-of-an-immigrant-population-of-chronic-schistosomiasis-sufferers-with-long-term-residence-in-a-non-endemic-country-north-metropolitan-area-of-barcelona-2002-2016
#20
Sílvia Roure, Lluís Valerio, Olga Pérez-Quílez, Gema Fernández-Rivas, Octavio Martínez-Cuevas, Albert Alcántara-Román, Diego Viasus, M Luisa Pedro-Botet, Miquel Sabrià, Bonaventura Clotet
BACKGROUND: Schistosomiasis, one of the neglected tropical diseases (NTD) listed by the WHO, is an acute and chronic parasitic disease caused by blood flukes (trematode worms) of the genus Schistosoma. Complications of long-term infestation include liver cirrhosis, bladder tumors and kidney failure. The objective of this study was to carry out a clinical and epidemiological characterization of a schistosomiasis-diagnosed immigrant population with long-term residencein the EU as well as to evaluate the diagnostic methods available to date...
2017: PloS One
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