keyword
MENU ▼
Read by QxMD icon Read
search

Pertussis vaccine

keyword
https://www.readbyqxmd.com/read/28318766/bacille-calmette-gu%C3%A3-rin-bcg-vaccination-at-birth-and-antibody-responses-to-childhood-vaccines-a-randomised-clinical-trial
#1
Thomas Nørrelykke Nissen, Nina Marie Birk, Gaby Smits, Dorthe Lisbeth Jeppesen, Lone Graff Stensballe, Mihai G Netea, Fiona van der Klis, Christine Stabell Benn, Ole Pryds
INTRODUCTION: BCG vaccination has been associated with beneficial non-specific effects on child health. Some immunological studies have reported heterologous effects of vaccines on antibody responses to heterologous vaccines. Within a randomised clinical trial of Bacille Calmette-Guérin (BCG) vaccination at birth, The Danish Calmette Study, we investigated the effect of BCG at birth on the antibody response to the three routine vaccines against DiTeKiPol/Act-Hib and Prevenar 13 in a subgroup of participants...
March 15, 2017: Vaccine
https://www.readbyqxmd.com/read/28301611/gtl001-a-bivalent-therapeutic-vaccine-against-human-papillomavirus-16-and-18-induces-antigen-specific-cd8-t-cell-responses-leading-to-tumor-regression
#2
Michaël Esquerré, Myriam Bouillette-Marussig, Anne Goubier, Marie Momot, Christophe Gonindard, Hélène Keller, Astrid Navarro, Marie-Christine Bissery
BACKGROUND: Prophylactic vaccines are available for women and girls not yet infected with HPV, but women already infected with HPV need a treatment to prevent progression to high-grade cervical lesions and cancer. GTL001 is a bivalent therapeutic vaccine for eradicating HPV-infected cells that contains HPV16 E7 and HPV18 E7 both fused to detoxified adenylate cyclase from Bordetella pertussis, which binds specifically to CD11b+ antigen-presenting cells. This study examined the ability of therapeutic vaccination with GTL001 adjuvanted with topical imiquimod cream to induce functional HPV16 E7- and HPV18 E7-specific CD8+ T cell responses...
2017: PloS One
https://www.readbyqxmd.com/read/28301394/effects-on-the-anti-abo-titers-of-military-blood-donors-from-a-predeployment-vaccination-program
#3
Olle Berséus
BACKGROUND: The use of blood group O as "universal blood" for emergency whole blood transfusions carries the risk for a hemolytic transfusion reaction mediated by incompatible A-/B-antibodies. This risk can be minimized by assuring that the donor has a low titer of anti-A and anti-B. The level of these naturally occurring antibodies have been shown to be increased by vaccination with most biologically derived vaccines. This boostering effect has been investigated for the new generation of vaccines...
March 15, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28301267/hypotonic-hyporesponsive-episodes-after-administration-of-hexavalent-dtp-based-combination-vaccine-a-description-of-12-cases
#4
Alessandro Vigo, Giulia Costagliola, Elisa Ferrero, Silvia Noce
Hypotonic-hyporesponsive (HHE) episodes are known and recognized phenomena, which typically occur within 48 hours of immunisation..Our aim is to describe 12 cases of HHE brought to the Center of Pediatric Sleep Medicine, with attention to the clinical features of the episode and their follow-up. Medical charts of infants visited between 2005-2015 were reviewed. Twelve infants showed a HHE using HHE using Brighton Collaboration Criteria. All infants received a Hexavalent diphtheria -tetanus -pertussis acellular component -hepatitis B-,inactivated poliovirus- Haemophilus influenzae type-b conjugate vaccine...
February 21, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28291499/pertussis-outbreak-among-soldiers-during-basic-training-the-need-for-updated-protocols
#5
Basheer Halhal, Yuval Glick, Inbal Galor, Ankory Ran, David J Bacon, Elon Glassberg
Pertussis is a highly contagious, vaccine preventable upper respiratory disease. The incidence of the disease has been rising in the past few decades. During the winter of 2015, an upper respiratory outbreak occurred in one of Israel Defense Forces basic training bases in northern Israel. Following the detection of the first primary cases, a suspected outbreak investigation was initiated in conjunction with more rigorous clinical and laboratory testing efforts to include specific antibody enzyme-linked immunosorbent assay assays and polymerase chain reaction to diagnose pertussis...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289064/what-is-wrong-with-pertussis-vaccine-immunity-the-problem-of-waning-effectiveness-of-pertussis-vaccines
#6
Nicolas Burdin, L K Handy, S A Plotkin
Pertussis is resurgent in some countries, particularly those in which children receive acellular pertussis (aP) vaccines in early infancy and boosters later in life. Immunologic studies show that, whereas whole-cell pertussis (wP) vaccines orient the immune system toward Th1/Th17 responses, acellular pertussis vaccines orient toward Th1/Th2 responses. Although aP vaccines do provide protection during the first years of life, the change in T-cell priming results in waning effectiveness of aP as early as 2-3 years post-boosters...
March 13, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28289059/what-is-wrong-with-pertussis-vaccine-immunity-why-immunological-memory-to-pertussis-is-failing
#7
Dimitri A Diavatopoulos, Kathryn Margaret Edwards
Memory responses seen after whole-cell pertussis (wP) and acellular pertussis (aP) vaccine priming are different and reflect better long-term protection against pertussis disease seen with the whole-cell vaccines. Although acellular vaccines generate higher levels of antigen-specific IgG to the antigens included in the aP vaccines, there are many more pertussis antigens included in whole-cell vaccines. Acellular vaccine priming is associated with skewing of the immune response to a more Th2-like response, whereas whole-cell priming is associated with a Th1/Th17 response...
March 13, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28289058/what-is-wrong-with-pertussis-vaccine-immunity-inducing-and-recalling-vaccine-specific-immunity
#8
Christiane S Eberhardt, Claire-Anne Siegrist
The high incidence of pertussis in vaccinated adolescents suggests the failing of immune memory. We argue that acellular pertussis vaccines generate memory cells that are effectively reactivated by boosters better than by Bordetella pertussis exposure. We propose that there are two main causes. One is the induction of vaccine-specific immunity rather than pathogen-specific immunity. The second is that strictly mucosal infections such as B. pertussis poorly reactivate memory B and T cells residing deep in lymph nodes or tissues...
March 13, 2017: Cold Spring Harbor Perspectives in Biology
https://www.readbyqxmd.com/read/28284678/analysis-of-the-effects-of-individual-and-community-level-factors-on-childhood-immunization-in-malawi
#9
Peter Austin Morton Ntenda, Kun-Yang Chuang, Fentanesh Nibret Tiruneh, Ying-Chih Chuang
BACKGROUND: Empirical evidence regarding the relationship between childhood immunization and individual- and community-level factors in low-income countries has received little attention. We compared the trends and the effects of a wide range of individual- and community-level socioeconomic factors on the likelihood of a child being immunized between 2004 and 2010 in Malawi. METHODS: We used data from the 2004 and 2010 Malawi Demographic and Health Survey and applied generalized estimating logistic regression equation to analyze data respectively on 2042 and 3496 children aged 12-23months...
March 8, 2017: Vaccine
https://www.readbyqxmd.com/read/28283011/-investigation-of-seropositivity-of-bordetella-pertussis-in-adults-in-a-university-hospital
#10
Lütfiye Öksüz, Nezahat Gürler, Ali Ağaçfidan
Whooping cough is a vaccine-preventable infectious diseases caused by Bordetella pertussis/parapertussis. Despite of routine immunization programs in the world, pertussis still remains endemic. Recently unvaccinated or partially immunized infants have infected with this pathogen and also increase of incidence was observed in adolescents and adults. The source of pertussis in newborns are attributed to household, especially due to the family members. Theaim of this study was to determine B.pertussis IgG antibody positivity by ELISA method in adults...
January 2017: Mikrobiyoloji Bülteni
https://www.readbyqxmd.com/read/28278415/paediatric-active-enhanced-disease-surveillance-inaugural-annual-report-2014
#11
Yvonne A Zurynski, Jocelynne E McRae, Helen E Quinn, Nicholas J Wood, Kristine K Macartney
INTRODUCTION: The Paediatric Active Enhanced Disease Surveillance (PAEDS) network is a hospital-based active surveillance system employing prospective case ascertainment of selected uncommon vaccine preventable diseases and potential adverse events following immunisation (AEFI). PAEDS enhances other Australian surveillance systems by providing prospective detailed clinical and laboratory data for the same child. METHODS: Specialist surveillance nurses screen hospital admissions, emergency department records, laboratory and other data, to prospectively identify hospitalised children aged under 15 years in 5 paediatric tertiary referral hospitals in New South Wales, Victoria, South Australia, Western Australia and Queensland...
September 30, 2016: Communicable Diseases Intelligence Quarterly Report
https://www.readbyqxmd.com/read/28278180/is-the-current-pertussis-incidence-only-the-results-of-testing-a-spatial-and-space-time-analysis-of-pertussis-surveillance-data-using-cluster-detection-methods-and-geographically-weighted-regression-modelling
#12
Boris Kauhl, Jeanne Heil, Christian J P A Hoebe, Jürgen Schweikart, Thomas Krafft, Nicole H T M Dukers-Muijrers
BACKGROUND: Despite high vaccination coverage, pertussis incidence in the Netherlands is amongst the highest in Europe with a shifting tendency towards adults and elderly. Early detection of outbreaks and preventive actions are necessary to prevent severe complications in infants. Efficient pertussis control requires additional background knowledge about the determinants of testing and possible determinants of the current pertussis incidence. Therefore, the aim of our study is to examine the possibility of locating possible pertussis outbreaks using space-time cluster detection and to examine the determinants of pertussis testing and incidence using geographically weighted regression models...
2017: PloS One
https://www.readbyqxmd.com/read/28277900/influence-of-maternal-vaccination-against-diphtheria-tetanus-and-pertussis-on-the-avidity-of-infant-antibody-responses-to-a-pertussis-containing-vaccine-in-belgium
#13
Raïssa Nadège Caboré, Kirsten Maertens, Alexandre Dobly, Elke Leuridan, Pierre Van Damme, Kris Huygen
Maternal antibodies induced by vaccination during pregnancy cross the placental barrier and can close the susceptibility gap to pertussis in young infants up to the start of primary immunization. As not only the quantity but also the quality of circulating antibodies is important for protection, we assessed whether maternal immunization affects the avidity of infant vaccine-induced IgG antibodies, in the frame of a prospective clinical trial on pregnancy vaccination in Belgium. Infants born from Tdap (Boostrix®) vaccinated (N = 55) and unvaccinated (N = 26) mothers were immunized with a hexavalent pertussis containing vaccine (Infanrix Hexa®) at 8, 12 and 16 weeks, followed by a fourth dose at 15 months of age...
February 22, 2017: Virulence
https://www.readbyqxmd.com/read/28272332/knowledge-attitude-and-behaviours-towards-recommended-vaccinations-among-healthcare-workers
#14
Giuseppe La Torre, Stefania Scalingi, Veronica Garruto, Marco Siclari, Massimiliano Chiarini, Alice Mannocci
Healthcare workers (HCWs) are an important group of professionals exposed to biological risk during their work activities. So, the aim of this study is to perform a survey on the knowledge, attitude and behaviour of Italian HCWs towards the vaccinations recommended by the Ministry of Health. A cross-sectional study was carried out during the period September 2014-August 2015 in the Lazio region. The study was conducted by recruiting HCWs and biomedical students. The sample was comprised of 571 responders, of whom 12...
March 7, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28262330/a-randomized-study-of-fever-prophylaxis-and-the-immunogenicity-of-routine-pediatric-vaccinations
#15
Jacek Wysocki, Kimberly J Center, Jerzy Brzostek, Ewa Majda-Stanislawska, Henryk Szymanski, Leszek Szenborn, Hanna Czajka, Barbara Hasiec, Jerzy Dziduch, Teresa Jackowska, Anita Witor, Elżbieta Kopińska, Ryszard Konior, Peter C Giardina, Vani Sundaraiyer, Scott Patterson, William C Gruber, Daniel A Scott, Alejandra Gurtman
OBJECTIVE: Prophylactic antipyretic use during pediatric vaccination is common. This study assessed whether paracetamol or ibuprofen prophylaxis interfere with immune responses to the 13-valent pneumococcal conjugate vaccine (PCV13) given concomitantly with the combined DTaP/HBV/IPV/Hib vaccine. METHODS: Subjects received prophylactic paracetamol or ibuprofen at 0, 6-8, and 12-16 h after vaccination, or 6-8 and 12-16 h after vaccination at 2, 3, 4, and 12months of age...
March 2, 2017: Vaccine
https://www.readbyqxmd.com/read/28256284/human-papillomavirus-vaccine-uptake-increase-for-american-indian-adolescents-2013-2015
#16
Jasmine L Jacobs-Wingo, Cheyenne C Jim, Amy V Groom
INTRODUCTION: Although Indian Health Service, tribally-operated, and urban Indian (I/T/U) healthcare facilities have higher human papillomavirus (HPV) vaccine series initiation and completion rates among adolescent patients aged 13-17 years than the general U.S. population, challenges remain. I/T/U facilities have lower coverage for HPV vaccine first dose compared with coverage for other adolescent vaccines, and HPV vaccine series completion rates are lower than initiation rates. Researchers aimed to assist I/T/U facilities in identifying interventions to increase HPV vaccination series initiation and completion rates...
February 27, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28253995/policy-making-for-vaccine-use-as-a-driver-of-vaccine-innovation-and-development-in-the-developed-world
#17
REVIEW
Katherine Seib, Andrew J Pollard, Philippe de Wals, Ross M Andrews, Fangjun Zhou, Richard J Hatchett, Larry K Pickering, Walter A Orenstein
In the past 200years, vaccines have had unmistakable impacts on public health including declines in morbidity and mortality, most markedly in economically-developed countries. Highly engineered vaccines including vaccines for conditions other than infectious diseases are expected to dominate future vaccine development. We examine immunization vaccine policy as a driver of vaccine innovation and development. The pathways to recommendation for use of licensed vaccines in the US, UK, Canada and Australia have been similar, including: expert review of disease epidemiology, disease burden and severity; vaccine immunogenicity, efficacy and safety; programmatic feasibility; public demand; and increasingly cost-effectiveness...
March 7, 2017: Vaccine
https://www.readbyqxmd.com/read/28249007/safety-evaluation-of-a-vaccine-effect-in-maternal-reproductive-outcome-and-fetal-anomaly-frequency-in-rats-using-a-leishmanial-vaccine-as-a-model
#18
Rafaianne Q Moraes-Souza, Ana Paula Reinaque, Thaigra S Soares, Ana Luiza T Silva, Rodolfo C Giunchetti, Maria A S Takano, Milena A Akamatsu, Flávia S Kubrusly, Fernanda Lúcio-Macarini, Isaias Raw, Dmitri Iourtov, Paulo Lee Ho, Lilian L Bueno, Ricardo T Fujiwara, Gustavo T Volpato
While the immunogenic potential of the vaccination against infectious diseases was extensively shown, data on the safety assessment of recombinant proteins in vaccine formulations administered during pregnancy are still scarce. In the current study, the antigenicity of a vaccine against leishmaniasis (based on Leishmania braziliensis recombinant protein peroxidoxin) during pregnancy and possible maternal reproductive outcomes and fetal anomalies after immunization with a leishmanial vaccine or adjuvant alone (Bordetella pertussis derived MPLA adjuvant) were assessed...
2017: PloS One
https://www.readbyqxmd.com/read/28246672/electronic-alerts-improve-immunization-rates-in-two-month-old-premature-infants-hospitalized-in-the-neonatal-intensive-care-unit
#19
Kimberly D Ernst
OBJECTIVE: To determine if an electronic alert improves 2 month immunization rates in infants remaining hospitalized in the neonatal intensive care unit. METHODS: Institutional Review Board-approved retrospective chart review of 261 infants with birth weights <2 kg and still hospitalized at ≥ 58 days. Charts were reviewed between 2009 and 2013, before and after the 2011 electronic alert was instituted in the electronic medical record from days 56 to 67 to remind providers that immunizations were due...
March 1, 2017: Applied Clinical Informatics
https://www.readbyqxmd.com/read/28243609/meta-analysis-of-pulmonary-transcriptomes-from-differently-primed-mice-identifies-molecular-signatures-to-differentiate-immune-responses-following-bordetella-pertussis-challenge
#20
René H M Raeven, Jeroen L A Pennings, Elly van Riet, Gideon F A Kersten, Bernard Metz
Respiratory infection with Bordetella pertussis leads to severe effects in the lungs. The resulting immunity and also immunization with pertussis vaccines protect against disease, but the induced type of immunity and longevity of the response are distinct. In this study the effects of priming, by either vaccination or infection, on a subsequent pathogen encounter were studied. To that end, three postchallenge transcriptome datasets of previously primed mice were combined and compared to the responses in unprimed control mice...
2017: Journal of Immunology Research
keyword
keyword
51190
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"