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Motor Evoked Potentials

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https://www.readbyqxmd.com/read/28430708/the-somatosensory-evoked-potential-in-reaction-time-is-gated-and-elicited-earlier-when-the-motor-response-to-a-somatosensory-cue-is-faster
#1
Koichi Hiraoka, Chisato Kori, Kana Sato
The aim of this study was to investigate whether the somatosensory-evoked potential (SEP) is gated and elicited earlier when a motor response to a somatosensory stimulus is faster. In healthy humans, the left index finger and thumb were pinched in response to a somatosensory stimulus administered over the left median nerve. The SEP elicited by this stimulus when producing a fast motor response was compared with that when producing a slow motor response. The amplitudes of N18 and frontal P40 when producing a fast motor response were smaller than those when producing a slow motor response...
April 20, 2017: Neuroreport
https://www.readbyqxmd.com/read/28423347/experimental-study-of-brachial-plexus-and-vessel-compression-evaluation-of-combined-central-and-peripheral-electrodiagnostic-approach
#2
Chaoqun Yang, Jianguang Xu, Jie Chen, Shulin Li, Yu Cao, Yi Zhu, Lei Xu
INTRODUCTION: We sought to investigate the reliability of a new electrodiagnostic method for identifying Electrodiagnosis of Brachial Plexus & Vessel Compression Syndrome (BPVCS) in rats that involves the application of transcranial electrical stimulation motor evoked potentials (TES-MEPs) combined with peripheral nerve stimulation compound muscle action potentials (PNS-CMAPs). RESULTS: The latencies of the TES-MEP and PNS-CMAP were initially elongated in the 8-week group...
April 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28423317/loss-of-nav%C3%AE-4-mediated-regulation-of-sodium-currents-in-adult-purkinje-neurons-disrupts-firing-and-impairs-motor-coordination-and-balance
#3
Joseph L Ransdell, Edward Dranoff, Brandon Lau, Wan-Lin Lo, David L Donermeyer, Paul M Allen, Jeanne M Nerbonne
The resurgent component of voltage-gated Na(+) (Nav) currents, INaR, has been suggested to provide the depolarizing drive for high-frequency firing and to be generated by voltage-dependent Nav channel block (at depolarized potentials) and unblock (at hyperpolarized potentials) by the accessory Navβ4 subunit. To test these hypotheses, we examined the effects of the targeted deletion of Scn4b (Navβ4) on INaR and on repetitive firing in cerebellar Purkinje neurons. We show here that Scn4b(-/-) animals have deficits in motor coordination and balance and that firing rates in Scn4b(-/-) Purkinje neurons are markedly attenuated...
April 18, 2017: Cell Reports
https://www.readbyqxmd.com/read/28420581/response-variability-of-different-anodal-transcranial-direct-current-stimulation-intensities-across-multiple-sessions
#4
Claudia Ammann, Martin A Lindquist, Pablo A Celnik
BACKGROUND: It is well known that transcranial direct current stimulation (tDCS) is capable of modulating corticomotor excitability. However, a source of growing concern has been the observed inter- and intra-individual variability of tDCS-responses. Recent studies have assessed whether individuals respond in a predictable manner across repeated sessions of anodal tDCS (atDCS). The findings of these investigations have been inconsistent, and their methods have some limitations (i.e. lack of sham condition or testing only one tDCS intensity)...
April 10, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28418363/-correlation-of-the-intra-operative-neuromonitoring-data-and-emg-characteristics-of-post-operative-motor-deficit-in-patients-with-spinal-deformities
#5
А P Shein, М S Sayphutdinov, А А Skripnikov, G А Krivoruchko, S О Ryabykh
AIM: To correlate electroneuromyigraphic (ENMG) manifestations of post-operative motor deficit developed in patients after spinal deformity correction with qualitative evaluation of the severity of intra-operative pyramidal disorders according to protocol of intra-operative neuromonitoring (IONM). MATERIAL AND METHODS: ENMG data of 87 patients aged 6-43 years with spinal deformities of different etiology were analyzed before and after surgical correction and were correlated with intra-operative neuromonitoring course...
2017: Khirurgiia
https://www.readbyqxmd.com/read/28418103/neurogenic-and-myogenic-patterns-of-electrical-activity-in-isolated-intact-mouse-colon
#6
T J Hibberd, M Costa, L Travis, S J H Brookes, D A Wattchow, J Feng, H Hu, N J Spencer
BACKGROUND: Relatively little is known about the electrical rhythmicity of the whole colon, where long neural pathways are preserved. METHODS: Smooth muscle electrical activity was recorded extracellularly from the serosa of isolated flat-sheet preparations consisting of the whole mouse colon (n=31). KEY RESULTS: Two distinct electrical patterns were observed. The first, long intense spike bursts, occurred every 349±256 seconds (0.2±0.2 cpm), firing action potentials for 31±11 seconds at 2...
April 18, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28409395/spinal-and-corticospinal-pathways-are-differently-modulated-when-standing-at-the-bottom-and-the-top-of-a-three-step-staircase-in-young-and-older-adults
#7
Johanna Johannsson, Jacques Duchateau, Stéphane Baudry
PURPOSE: This study investigated the modulation of spinal (group Ia afferents) and corticospinal pathways when young (22.7 ± 1.3 years) and older adults (72.2 ± 7.9 years) stood at the bottom and at the top of a three-step staircase equipped with force platforms. METHOD: Changes in submaximal H-reflex amplitude (H 50) and slope of the H-reflex input-output relation (spinal pathway), and in amplitude of motor-evoked potentials (MEP) triggered by transcranial magnetic stimulation (corticospinal pathway) at two intensities (1...
April 13, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28408638/blindfolding-during-wakefulness-causes-decrease-in-sleep-slow-wave-activity
#8
Eva Magdalena Korf, Matthias Mölle, Jan Born, Hong-Viet V Ngo
Slow wave activity (SWA, 0.5-4 Hz) represents the predominant EEG oscillatory activity during slow wave sleep (SWS). Its amplitude is considered in part a reflection of synaptic potentiation in cortical networks due to encoding of information during prior waking, with higher amplitude indicating stronger potentiation. Previous studies showed that increasing and diminishing specific motor behaviors produced corresponding changes in SWA in the respective motor cortical areas during subsequent SWS Here, we tested whether this relationship can be generalized to the visual system, that is, whether diminishing encoding of visual information likewise leads to a localized decrease in SWA over the visual cortex...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28406812/electroencephalography-predicts-poor-and-good-outcomes-after-cardiac-arrest-a-two-center-study
#9
Andrea O Rossetti, Diego F Tovar Quiroga, Elsa Juan, Jan Novy, Roger D White, Nawfel Ben-Hamouda, Jeffrey W Britton, Mauro Oddo, Alejandro A Rabinstein
OBJECTIVE: The prognostic role of electroencephalography during and after targeted temperature management in postcardiac arrest patients, relatively to other predictors, is incompletely known. We assessed performances of electroencephalography during and after targeted temperature management toward good and poor outcomes, along with other recognized predictors. DESIGN: Cohort study (April 2009 to March 2016). SETTING: Two academic hospitals (Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; Mayo Clinic, Rochester, MN)...
April 12, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28405184/optical-imaging-of-the-motor-cortex-following-antidromic-activation-of-the-corticospinal-tract-after-spinal-cord-injury
#10
Kyung H Lee, Un J Kim, Se W Park, Yong G Park, Bae H Lee
Spinal cord injury (SCI) disrupts neuronal networks of ascending and descending tracts at the site of injury, leading to a loss of motor function. Restoration and new circuit formation are important components of the recovery process, which involves collateral sprouting of injured and uninjured fibers. The present study was conducted to determine cortical responses to antidromic stimulation of the corticospinal tracts, to compare changes in the reorganization of neural pathways within normal and spinal cord-injured rats, and to elucidate differences in spatiotemporal activity patterns of the natural progression and reorganization of neural pathways in normal and SCI animals using optical imaging...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28404231/modulation-of-sensorimotor-circuits-during-retrieval-of-negative-autobiographical-memories-exploring-the-impact-of-personality-dimensions
#11
Ludovico Mineo, Carmen Concerto, Dhaval Patel, Tyrone Mayorga, Eileen Chusid, Carmenrita Infortuna, Eugenio Aguglia, Yasmin Sarraf, Fortunato Battaglia
Autobiographical Memory (AM) retrieval refers to recollection of experienced past events. Previous Transcranial Magnetic Stimulation (TMS) studies have shown that presentation of emotional negative stimuli affects human motor cortex excitability resulting in larger motor evoked potentials (MEPs). Up to date no TMS studies have been carried out in order to investigate the effect of personal memories with negative emotional value on corticospinal excitability. In this study we hypothesized that negative AM retrieval will modulate corticomotor excitability and sensorimotor integration as determined by TMS neurophysiological parameters...
April 9, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28402868/age-related-differences-in-twitch-properties-and-muscle-activation-of-the-first-dorsal-interosseous
#12
Jonathan D Miller, Trent J Herda, Michael A Trevino, Adam J Sterczala, Anthony B Ciccone, Justin X Nicoll
OBJECTIVE: To examine twitch force potentiation and twitch contraction duration, as well as electromyographic amplitude (EMGRMS) and motor unit mean firing rates (MFR) at targeted forces between young and old individuals in the first dorsal interosseous (FDI). Ultrasonography was used to assess muscle quality. METHODS: Twenty-two young (YG) (age=22.6±2.7years) and 14 older (OD) (age=62.1±4.7years) individuals completed conditioning contractions at 10% and 50% maximal voluntary contraction, (MVC) during which EMGRMS and MFRs were assessed...
March 24, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28402573/humor-drawings-evoked-temporal-and-spectral-eeg-processes
#13
Regina W Y Wang, Hsien-Chu Kuo, Shang-Wen Chuang
The study aimed to explore the humor processing elicited through the manipulation of artistic drawings. Using the Comprehension-Elaboration Theory of humor as the main research background, the experiment manipulated the head portraits of celebrities based on the independent variables of facial deformation (large/small) and addition of affective features (positive/negative). A 64-channel electroencephalography was recorded in 30 participants while viewing the incongruous drawings of celebrities. The electroencephalography temporal and spectral responses were measured during the three stages of humor which included incongruity detection, incongruity comprehension and elaboration of humor...
April 11, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28400096/the-evolution-of-motor-cortical-dysfunction-in-amyotrophic-lateral-sclerosis
#14
Kazumoto Shibuya, Neil G Simon, Nimeshan Geevasinga, Parvathi Menon, James Howells, Susanna B Park, William Huynh, Yu-Ichi Noto, Steve Vucic, Matthew C Kiernan
OBJECTIVE: The present study aimed to investigate alterations in cortical function in amyotrophic lateral sclerosis (ALS) related to disease progression. METHODS: In total, clinical assessments were evaluated in 189 ALS patients, combined with assessment of cortical function utilising threshold tracking transcranial magnetic stimulation. Results were compared with disease stage. Disease stage was defined in three ways: (1) as a proportion of disease duration in deceased patients; (2) from the time of ALS onset; and (3) using the ALS rating scale-revised (ALSFRS-R)...
March 15, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28394475/dynamical-entrainment-of-corticospinal-excitability-during-rhythmic-movement-observation-a-tms-study
#15
Manuel Varlet, Giacomo Novembre, Peter E Keller
Spontaneous modulations of corticospinal excitability during action observation have been interpreted as evidence for the activation of internal motor representations equivalent to the observed action. Alternatively or complementary to this perspective, growing evidence shows that motor activity during observation of rhythmic movements can be modulated by direct visuomotor couplings and dynamical entrainment. In-phase and anti-phase entrainment spontaneously occur, characterized by cyclic movements proceeding simultaneously in the same (in-phase) or opposite (anti-phase) direction...
April 10, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28393259/sequential-modulation-of-bottom-up-response-activation-and-inhibition-in-a-response-conflict-task-a-single-pulse-transcranial-magnetic-stimulation-study
#16
Barbara Treccani, Giorgia Cona, Nadia Milanese, Carlo Umiltà
Many cognitive tasks involve a response conflict between the response selected on the basis of the task-relevant attribute and that primed by an irrelevant attribute. Although response priming has been extensively investigated, we still have little evidence on whether it entails both excitatory and inhibitory processes and the way in which these processes are modulated by the prior occurrence of a conflict between-response alternatives. To shed light on these issues, we tested motor cortex excitability during a two-choice compatibility task (a Simon task) by delivering single pulses of transcranial magnetic stimulation and recording the resulting motor evoked potentials (MEPs)...
April 9, 2017: Psychological Research
https://www.readbyqxmd.com/read/28392766/presence-and-absence-of-muscle-contraction-elicited-by-peripheral-nerve-electrical-stimulation-differentially-modulate-primary-motor-cortex-excitability
#17
Ryoki Sasaki, Shinichi Kotan, Masaki Nakagawa, Shota Miyaguchi, Sho Kojima, Kei Saito, Yasuto Inukai, Hideaki Onishi
Modulation of cortical excitability by sensory inputs is a critical component of sensorimotor integration. Sensory afferents, including muscle and joint afferents, to somatosensory cortex (S1) modulate primary motor cortex (M1) excitability, but the effects of muscle and joint afferents specifically activated by muscle contraction are unknown. We compared motor evoked potentials (MEPs) following median nerve stimulation (MNS) above and below the contraction threshold based on the persistence of M-waves. Peripheral nerve electrical stimulation (PES) conditions, including right MNS at the wrist at 110% motor threshold (MT; 110% MNS condition), right MNS at the index finger (sensory digit nerve stimulation [DNS]) with stimulus intensity approximately 110% MNS (DNS condition), and right MNS at the wrist at 90% MT (90% MNS condition) were applied...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28390090/prepotent-motor-activity-and-inhibitory-control-demands-in-different-variants-of-the-go-no-go-paradigm
#18
Jan R Wessel
Inhibitory control enables humans to stop prepotent motor activity, and is commonly studied using go/no-go or stop-signal tasks. In stop-signal tasks, prepotent motor activity is elicited by delaying stop signals relative to go signals. In go/no-go tasks, however, trials include only one signal-go or no-go. Hence, prepotent motor activity has to be ensured differently-for example, by using rare no-go trials and short trial durations. However, a literature survey shows that ∼40% of studies use equiprobable go/no-go trials and ∼20% use long stimulus-stimulus intervals (> 4 s)...
April 8, 2017: Psychophysiology
https://www.readbyqxmd.com/read/28389338/bi-phasic-activation-of-the-primary-motor-cortex-by-pain-and-its-relation-to-pain-evoked-potentials-an-exploratory-study
#19
Lee-Bareket Kisler, Irit Weissman-Fogel, Alon Sinai, Elliot Sprecher, Andrei V Chistyakov, Simone Shamay-Tsoory, Nadav Moscovitz, Yelena Granovsky
The primary motor cortex (M1) is a known target for brain stimulation aimed at pain alleviation in chronic pain patients, yet the mechanisms through which analgesia occurs, and the exact pain-motor interrelations are not fully understood. We used noxious contact heat evoked potentials (CHEPs) and cortical source analysis to further explore the relevance of M1 in pain processing. Twenty-four healthy young females received brief noxious heat stimuli to their left non-dominant volar forearm, simultaneously with CHEPs recordings...
April 4, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28388686/vestibular-stimulation-induced-facilitation-of-cervical-premotoneuronal-systems-in-humans
#20
Shinya Suzuki, Tsuyoshi Nakajima, Shun Irie, Ryohei Ariyasu, Tomoyoshi Komiyama, Yukari Ohki
It is unclear how descending inputs from the vestibular system affect the excitability of cervical interneurons in humans. To elucidate this, we investigated the effects of galvanic vestibular stimulation (GVS) on the spatial facilitation of motor-evoked potentials (MEPs) induced by combined pyramidal tract and peripheral nerve stimulation. To assess the spatial facilitation, electromyograms were recorded from the biceps brachii muscles (BB) of healthy subjects. Transcranial magnetic stimulation (TMS) over the contralateral primary motor cortex and electrical stimulation of the ipsilateral ulnar nerve at the wrist were delivered either separately or together, with interstimulus intervals of 10 ms (TMS behind)...
2017: PloS One
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