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Chlorhexidine wipe

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https://www.readbyqxmd.com/read/28803661/daily-bathing-strategies-and-cross-transmission-of-multidrug-resistant-organisms-impact-of-chlorhexidine-impregnated-wipes-in-a-multidrug-resistant-gram-negative-bacteria-endemic-intensive-care-unit
#1
Jesus Ruiz, Paula Ramirez, Esther Villarreal, Monica Gordon, Inmaculada Saez, Alfonso Rodríguez, María Jesús Castañeda, Álvaro Castellanos-Ortega
BACKGROUND: Health-care associated infections are a major cause of morbidity and mortality in critical care units. The aim of this study is to evaluate the effectiveness of chlorhexidine gluconate (CHG)-impregnated wipes in the daily bathing of patients in an intensive care unit (ICU) to prevent cross-transmission and colonization by multidrug-resistant organisms (MDROs) METHODS: Prospective cohort study with an intervention of 11 months. The intervention consisted of using CHG-impregnated wipes for the daily bathing of patients on mechanical ventilation or colonized by MDROs...
August 10, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28738398/the-compatibility-of-chlorhexidine-and-a-skin-care-product-line-a-real-world-analysis-of-hospital-acquired-infection-rates
#2
Priscilla L Phillips, Daniel Young, Debashish Chakravarthy
Chlorhexidine gluconate (CHG) use helps reduce hospital-acquired infections (HAIs). Chlorhexidine gluconate effectiveness can be reduced by use of skin care products. Although laboratory work can be performed to prove compatibility, such work has limitations. The purpose of this study was to compare HAI rates when CHG antiseptic wipes were used in conjunction with a silicone- and micronutrient-based skin care product line (SMSP) and when CHG wipes were used without the SMSP. Using commercial distribution data, 17 hospitals that purchased both CHG wipes and SMSP were identified...
July 2017: Health Care Manager
https://www.readbyqxmd.com/read/28694729/the-alcohol-used-for-cleansing-the-venipuncture-site-does-not-jeopardize-blood-and-plasma-alcohol-measurement-with-head-space-gas-chromatography-and-an-enzymatic-assay
#3
Giuseppe Lippi, Ana-Maria Simundic, Giacomo Musile, Elisa Danese, Gianluca Salvagno, Franco Tagliaro
INTRODUCTION: This study aimed to establish whether an alcoholic antiseptic, wiped or not before venipuncture, may jeopardize alcohol testing with a commercial enzymatic assay and a reference head-space gas chromatography (GC) technique. MATERIALS AND METHODS: Venous blood was collected from 23 healthy volunteers, with two sequential procedures. In the first blood collection, 2 mL of alcoholic antiseptic (0.5% chlorhexidine, 70% ethanol) were place on a gauge pad, the venipuncture site of right arm was cleaned but the antiseptic was not let to dry before phlebotomy...
June 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28655955/comparison-of-efficacy-and-cost-effectiveness-of-0-55-ortho-phthalaldehyde-and-2-glutaraldehyde-for-disinfection-of-laryngoscopes-a-prospective-pilot-study
#4
Priyanka Pradeep Karnik, Nandini Malay Dave, Gita Nataraj, Rajarshi Gupta, Madhu Garasia
BACKGROUND AND AIMS: The laryngoscope is a potential source of cross-infection as it involves contact with the mucous membrane, saliva and occasionally blood. This study compared efficacy and cost-effectiveness of two Centre for Disease Control approved agents for disinfection of laryngoscope blades. METHODS: One hundred and sixty patients requiring laryngoscopy and intubation for general anaesthesia were randomly allocated into two groups. After tracheal intubation, used laryngoscope blades were cleaned with tap water...
June 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28405039/disinfection-of-laryngoscopes-a-survey-of-practice
#5
Vaishali Prabhakar Chaskar, Nandini Malay Dave, Raylene Dias, Priyanka Karnik
BACKGROUND AND AIMS: The laryngoscope is a common piece of equipment used by anaesthesiologists. It has been identified as a potential source of cross infection. Although guidelines exist regarding appropriate disinfection practices, recent reviews suggest ineffectiveness of current methods of disinfection and poor compliance with the established protocols. We conducted a questionnaire-based survey to study the current disinfection practices being followed by a cross section of anaesthesiologists...
March 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28332593/injections-through-skin-colonized-with-staphylococcus-aureus-biofilm-introduce-contamination-despite-standard-antimicrobial-preparation-procedures
#6
Yi Wang, Valery Leng, Viraj Patel, K Scott Phillips
While surgical site preparation has been extensively studied, there is little information about resistance of skin microbiota in the biofilm form to antimicrobial decontamination, and there are no quantitative models to study how biofilm might be transferred into sterile tissue/implant materials during injections for joint spine and tendon, aspiration biopsies and dermal fillers (DF). In this work, we develop two in vitro models to simulate the process of skin preparation and DF injection using pig skin and SimSkin (silicone) materials, respectively...
March 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28141597/genital-region-cleansing-wipes-effects-on-urine-culture-contamination
#7
Mehmet Burak Selek, Bayhan Bektöre, Ogün Sezer, Tuğba Kula Atik, Orhan Baylan, Mustafa Özyurt
INTRODUCTION: Urine culture is the gold standard test for revealing the microbial agent causing urinary tract infection (UTI). Culture results are affected by sampling techniques; improper sampling leads to contamination of urine and thus contamination of the culture with urogenital flora. We aimed to evaluate the effect of urogenital cleansing, performed with chlorhexidine-containing genital region cleansing wipes (GRCW) on contamination rates. METHODOLOGY: A total of 2,665 patients with UTI-related complaints and with urine culture requests from various outpatient clinics were enrolled in the study...
January 30, 2017: Journal of Infection in Developing Countries
https://www.readbyqxmd.com/read/28107301/implementation-of-a-pediatric-orthopaedic-bundle-to-reduce-surgical-site-infections
#8
Jan Schriefer, James Sanders, Julie Michels, Kori Wolcott, Connor Ruddy, Jenna Hanson
Surgical site infections (SSIs) cost an estimated $27,288 per case. An analysis of the National Surgical Quality Improvement Program data at the University of Rochester Medical Center suggested that rates of SSIs could be lowered in comparison with both peers and baseline. The aim of this study was to reduce the number of SSIs to zero through the implementation of a "bundle" or a combination of practices. Meetings were held with the multidisciplinary care team that includes surgeons and staff from pediatric pharmacy, pediatric infectious diseases, anesthesia, and nursing to create a care bundle for all pediatric orthopaedic surgery patients...
January 2017: Orthopaedic Nursing
https://www.readbyqxmd.com/read/27852955/microbiological-efficacy-of-early-mrsa-treatment-in-cystic-fibrosis-in-a-randomised-controlled-trial
#9
Marianne Sponer Muhlebach, Valeria Beckett, Elena Popowitch, Melissa B Miller, Arthur Baines, Nicole Mayer-Hamblett, Edith T Zemanick, Wynton C Hoover, Jill M VanDalfsen, Preston Campbell, Christopher H Goss
OBJECTIVE: To evaluate microbiological effectiveness, that is, culture negativity of a non-blinded eradication protocol (Rx) compared with observation (Obs) in clinically stable cystic fibrosis participants with newly positive methicillin resistant Staphylococcusaureus (MRSA) cultures. DESIGN: This non-blinded trial randomised participants ages 4-45 years with first or early (≤2 positive cultures within 3 years) MRSA-positive culture without MRSA-active antibiotics within 4 weeks 1:1 to Rx or Obs...
April 2017: Thorax
https://www.readbyqxmd.com/read/27828836/the-impact-of-a-universal-decolonization-protocol-on-hospital-acquired-methicillin-resistant-staphylococcus-aureus-in-a-burn-population
#10
Arthur T Johnson, Rachel M Nygaard, Ellie M Cohen, Ryan M Fey, Anne Lambert Wagner
Hospital-acquired (HA) methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of HA infections and a significant concern for burn centers. The use of 2% chlorhexidine-impregnated wipes and nasal mupirocin significantly decreases the rate of HA-MRSA in adult intensive care units. The aim of this study was to examine the impact of universal decolonization on the rate of MRSA conversion in an American Burn Association verified adult and pediatric burn center. Universal decolonization protocol consisting of daily chlorhexidine baths and a 5-day course of nasal mupirocin was implemented in the burn unit...
November 2016: Journal of Burn Care & Research: Official Publication of the American Burn Association
https://www.readbyqxmd.com/read/27583685/chlorhexidine-vaginal-wipes-prior-to-elective-cesarean-section-does-it-reduce-infectious-morbidity-a-randomized-trial
#11
Magdy R Ahmed, Nisreen K Aref, Waleed A Sayed Ahmed, Farzana R Arain
OBJECTIVE: To evaluate the efficacy of preoperative vaginal cleansing using chlorhexidine 0.25% antiseptic wipes on rates of postcesarean section (CS) infectious morbidities (endometritis, febrile morbidity and wound infection). METHODS: This prospective randomized trial was conducted among 218 pregnant women scheduled for term elective CS. Patients were equally divided into two groups by simple randomization. After spinal anesthesia and catheterization under aseptic technique, the study group had preoperative vaginal cleansing using chlorhexidine 0...
September 1, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27528869/predictors-of-staphylococcus-aureus-colonization-and-results-after-decolonization
#12
Tennison L Malcolm, Le Don Robinson, Alison K Klika, Deepak Ramanathan, Carlos A Higuera, Trevor G Murray
Protocols for the screening and decolonization of Staphylococcus aureus prior to total joint arthroplasty (TJA) have become widely adopted. The goals of this study were to determine: (1) whether implementation of a screening protocol followed by decolonization with mupirocin/vancomycin and chlorhexidine reduces the risk of revision compared with no screening protocol (i.e., chlorhexidine alone) and (2) whether clinical criteria could reliably predict colonization with MSSA and/or MRSA. Electronic medical records of primary patients undergoing TJA that were screened (n = 3,927) and were not screened (n = 1,751) for Staphylococcus aureus at least 4 days prior to surgery, respectively, were retrospectively reviewed...
2016: Interdisciplinary Perspectives on Infectious Diseases
https://www.readbyqxmd.com/read/27492790/reduction-of-methicillin-resistant-staphylococcus-aureus-infection-in-long-term-care-is-possible-while-maintaining-patient-socialization-a-prospective-randomized-clinical-trial
#13
Lance R Peterson, Susan Boehm, Jennifer L Beaumont, Parul A Patel, Donna M Schora, Kari E Peterson, Deborah Burdsall, Carolyn Hines, Maureen Fausone, Ari Robicsek, Becky A Smith
BACKGROUND: Antibiotic resistance is a challenge in long-term care facilities (LTCFs). The objective of this study was to demonstrate that a novel, minimally invasive program not interfering with activities of daily living or socialization could lower methicillin-resistant Staphylococcus aureus (MRSA) disease. METHODS: This was a prospective, cluster-randomized, nonblinded trial initiated at 3 LTCFs. During year 1, units were stratified by type of care and randomized to intervention or control...
December 1, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/26956247/does-preadmission-cutaneous-chlorhexidine-preparation-reduce-surgical-site-infections-after-total-knee-arthroplasty
#14
Bhaveen H Kapadia, Peter L Zhou, Julio J Jauregui, Michael A Mont
BACKGROUND: Many preventive methodologies seek to reduce the risk of surgical site infections after total knee arthroplasty (TKA), including the use of preoperative chlorhexidine baths and cloths. Although we have demonstrated in previous studies that this may be an efficacious method for infection prevention, our study was underpowered and we therefore set out to evaluate this with a larger sample size. QUESTIONS/PURPOSES: (1) Does a preadmission chlorhexidine cloth skin preparation protocol decrease the risk of surgical site infection in patients undergoing TKA? (2) When stratified using the National Healthcare Safety Network (NHSN) risk categories, which categories are associated with risk reduction from the preadmission chlorhexidine preparation protocol? METHODS: In our study, all patients (3717 total) who had undergone primary or revision TKA at a single institution between January 1, 2007, and December 31, 2013, were identified, of whom 991 patients used the chlorhexidine cloths before surgery and 2726 patients did not...
July 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/26894621/effectiveness-of-chlorhexidine-wipes-for-the-prevention-of-multidrug-resistant-bacterial-colonization-and-hospital-acquired-infections-in-intensive-care-unit-patients-a-randomized-trial-in-thailand
#15
RANDOMIZED CONTROLLED TRIAL
Adhiratha Boonyasiri, Peerapat Thaisiam, Chairat Permpikul, Tepnimitr Judaeng, Bordeesuda Suiwongsa, Napaporn Apiradeewajeset, Teerawan Fakthongphan, Sunun Suddee, Wandee Laoagtipparos, Visanu Thamlikitkul
OBJECTIVE: To determine the effectiveness of daily bathing with 2% chlorhexidine-impregnated washcloths in preventing multidrug-resistant (MDR) gram-positive bacterial colonization and bloodstream infection. METHODS: A randomized, open-label controlled trial was conducted in 4 medical intensive care units (ICUs) in Thailand from December 2013 to January 2015. Patients were randomized to receive cleansing with non-antimicrobial soap (control group) or 2% chlorhexidine-impregnated washcloths used to wipe the patient's body once daily (chlorhexidine group)...
March 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/26876749/management-of-a-hospital-outbreak-of-extensively-drug-resistant-acinetobacter-baumannii-using-a-multimodal-intervention-including-daily-chlorhexidine-baths
#16
A P Gray, R Allard, R Paré, T Tannenbaum, B Lefebvre, S Lévesque, M Mulvey, L Maalouf, S Perna, Y Longtin
BACKGROUND: Extensively drug-resistant Acinetobacter baumannii (XDR-Ab) is an increasingly important cause of healthcare-associated infection. Uncertainties remain concerning optimal control measures for healthcare-associated outbreaks. AIM: To describe the epidemiology and control of an XDR-Ab outbreak that involved multiple units of a large hospital from March 2012 to January 2014. METHODS: Case-finding included screening of rectum, groin, throat, nose, wounds, iatrogenic portals of entry, and catheterized sites...
May 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/26836053/is-staphylococcal-screening-and-suppression-an-effective-interventional-strategy-for-reduction-of-surgical-site-infection
#17
REVIEW
Charles E Edmiston, Nathan A Ledeboer, Blake W Buchan, Maureen Spencer, Gary R Seabrook, David Leaper
BACKGROUND: Staphylococcus aureus has been recognized as a major microbial pathogen for over 100 y, having the capacity to produce a variety of suppurative and toxigenic disease processes. Many of these infections are life-threatening, with particularly enhanced virulence in hospitalized patients with selective risk factors. Strains of methicillin-resistant Staphylococcus aureus (MRSA) have rapidly spread throughout the healthcare environment such that approximately 20% of S. aureus isolates recovered from surgical site infections are methicillin-resistant, (although this is now reducing following national screening and suppression programs and high impact interventions)...
April 2016: Surgical Infections
https://www.readbyqxmd.com/read/26638670/chlorhexidine-to-maintain-cleanliness-of-restroom-door-handles
#18
RANDOMIZED CONTROLLED TRIAL
Holly Young, Zara Plumb, James Stevenson, Annabelle Tibbett, Alexander Rawson, Joseph Thompsett, Mehroze Asif, Mignonne Gunasekara, Thomas Beresford-Peirse, Stuart Miller, Mark Blunt
Restroom internal door handles have the potential to become contaminated by pathogenic bacteria, particularly because frequent breakdowns occur in hand hygiene. Cleaning these door handles periodically could reduce this cross-contamination risk. The sustained effect following cleaning with chlorhexidine could be beneficial in restroom facilities as cleaning episodes are of necessity at time intervals. The cleaning efficacies and residual effects of Sani Cloth CHG 2% wipes were investigated in a double-blinded randomized crossover controlled trial in a school setting...
November 2015: Journal of Environmental Health
https://www.readbyqxmd.com/read/26597632/establishment-of-a-multi-species-biofilm-model-to-evaluate-chlorhexidine-efficacy
#19
R E Touzel, J M Sutton, M E Wand
BACKGROUND: Chronic infections, for example, diabetic foot ulcers, have a large impact in terms of patient morbidity and mortality. These wounds are characterized by complex polymicrobial communities of bacteria, which may include a number of difficult-to-eradicate multidrug-resistant pathogens. AIM: To establish a multi-species biofilm model to test the efficacy of chlorhexidine and chlorhexidine-containing formulas in eradication of polymicrobial biofilms. METHODS: A Centers for Disease Control and Prevention bioreactor was used to establish a multi-species biofilm incorporating Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis with equal numbers of each pathogen...
February 2016: Journal of Hospital Infection
https://www.readbyqxmd.com/read/26455757/daily-2-chlorhexidine-gluconate-bath-wash-in-a-tertiary-adult-intensive-care-and-high-dependency-units-to-reduce-risk-of-hospital-acquired-multi-resistant-organisms-a-best-practice-implementation-project
#20
REVIEW
Lizanne Dalgleish, Hardeep Jhattu, Judith Streak Gomersall
BACKGROUND: There is growing evidence that the incidence of hospital acquired multi resistant organisms are increasing worldwide. Intensive care patients are particularly prone to hospital-acquired infections. In an effort to combat increasing nosocomial infections rates within the intensive care/high dependency unit setting, Canberra Hospital has implemented a daily 2% chlorhexidine gluconate bath wash in combination as part of a best practice policy to reduce hospital acquired multi resistant organism rates of colonization...
2015: JBI Database of Systematic Reviews and Implementation Reports
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