keyword
https://read.qxmd.com/read/38490728/optimizing-the-glass-bead-sterilization-protocol-focusing-on-removal-of-organic-and-bacterial-intraoperative-contamination
#1
JOURNAL ARTICLE
Keith Lewy, Jonathan Bova, Timothy A Erickson, Robert Rose, Sara D Lawhon, Tracy H Vemulapalli
Validated glass bead sterilization protocols to effectively sterilize rodent surgical instruments after bacterial exposure (for example, cecal contamination) are lacking. To refine current approaches, we added either a multienzyme detergent, neutral pH detergent, or chlorhexidine scrub step before glass bead sterilization of forceps or needle drivers exposed to cecal contents. We exposed sets of forceps and needle drivers to cecal contents, which were then air dried for 3 min. Immediately after, the instruments were wiped several times with a clean, dry paper towel...
March 15, 2024: Journal of the American Association for Laboratory Animal Science: JAALAS
https://read.qxmd.com/read/38389492/disinfection-of-central-venous-access-device-needleless-connectors-a-human-factors-analysis
#2
JOURNAL ARTICLE
Frank A Drews, Richard A Martinello, Joan N Hebden, Keith H St John, David A Pegues
OBJECTIVE: Evidence-based central-line-associated bloodstream infection (CLABSI) prevention guidelines recommend the use of an antiseptic scrub to disinfect needleless connectors before device access. Guideline noncompliance may render disinfection ineffective. The goal of this study was to observe needleless-connector disinfection practices and to identify perceived facilitators and barriers to best practices of needleless-connector access. METHODS: A human factors mixed-methods study involving nursing focus groups of perceived barriers and facilitators and clinical observations of compliance with instructions and protocols for use of 3...
February 23, 2024: Infection Control and Hospital Epidemiology
https://read.qxmd.com/read/38342345/bathing-with-wipes-impregnated-with-chlorhexidine-gluconate-to-prevent-central-line-associated-bloodstream-infection-in-critically-ill-patients-a-systematic-review-with-meta-analysis
#3
REVIEW
Erica Almeida Carvalho Peixoto, Vanessa de Brito Poveda, Juliana Rizzo Gnatta, Ramon Antonio Oliveira
BACKGROUND: Recommendations for different types of bathing to prevent central line-associated bloodstream infections (CLABSI) are still divergent. The objective of this study was to verify whether bed bathing with wipes impregnated with 2% chlorhexidine (CHG) compared to conventional bed bathing is more effective in preventing CLABSI. METHODS: Systematic review of the literature by consulting the electronic databases PubMed/Medline, Embase, CINAHL, Scopus, and Web of Science from the date of inception until July 1, 2023, with no language or time restrictions...
February 10, 2024: American Journal of Infection Control
https://read.qxmd.com/read/38149889/does-a-presurgical-antisepsis-protocol-decrease-surgical-site-infections-in-young-children
#4
JOURNAL ARTICLE
Valerie Lapp, Bertha Ben Khallouq, Dana Bentley, Allie Kirkland, Jill Dykstra-Nykanen, Keith Ayotte
National standards for surgical site infection (SSI) prevention for children remain elusive. Our institution developed a presurgical antisepsis protocol that included the three components of chlorhexidine gluconate bathing wipes, chlorhexidine gluconate oral rinse, and povidone-iodine nasal swab. This retrospective cohort study examined data from electronic health records to compare SSI rates before and after protocol implementation. We included children aged 2 through 11 years undergoing any surgical procedure with the use of an incision in the OR (N = 1,356)...
January 2024: AORN Journal
https://read.qxmd.com/read/38012351/can-daily-bathing-with-4-chlorhexidine%C3%A2-%C3%A2-daily-chlorhexidine-wipe-for-1%C3%A2-week-be-effective-in-decolonizing-candida-auris-colonization
#5
JOURNAL ARTICLE
Umran Elbahr, Amira Khairy, Farouq Dayyab, Clark Steven Delos Reyes, Jennie Pastrana, Chithra Vineeth, Suha Hejres, Shruti Prem Sudha, Ozge Keskin, Shiv Singh Rana, Elias Fadel, Hakan Erdem, Oguz Resat Sipahi
BACKGROUND: Herein, it is aimed to present the decolonizing rates of Candida auris colonized cases after daily bathing with 4% chlorhexidine plus daily cleaning with 4% chlorhexidine wipe for 1 week (will be mentioned as DCHX). METHODS: The study period was from October, 2021, to November, 2022. Inclusion criteria were (i) age > 18, (ii) receiving DCHX, (iii) proven C. auris carrier on auricular, or axillar or inguinal swab surveillance cultures up to 5-day period before DCHX...
February 2024: European Journal of Clinical Microbiology & Infectious Diseases
https://read.qxmd.com/read/37967971/effectiveness-of-prophylactic-intranasal-photodynamic-disinfection-therapy-and-chlorhexidine-gluconate-body-wipes-for-surgical-site-infection-prophylaxis-in-adult-spine-surgery
#6
JOURNAL ARTICLE
Eryck Moskven, Daniel Banaszek, Eric C Sayre, Aleksandra Gara, Elizabeth Bryce, Titus Wong, Tamir Ailon, Raphaële Charest-Morin, Nicolas Dea, Marcel F Dvorak, Charles G Fisher, Brian K Kwon, Scott Paquette, John T Street
BACKGROUND: Current measures to prevent spinal surgical site infection (SSI) lack compliance and lead to antimicrobial resistance. We aimed to examine the effectiveness of bundled preoperative intranasal photodynamic disinfection therapy (nPDT) and chlorhexidine gluconate (CHG) body wipes in the prophylaxis of spine SSIs in adults, as well as determine our institutional savings attributable to the use of this strategy and identify adverse events reported with nPDT-CHG. METHODS: We performed a 14-year prospective observational interrupted time-series study in adult (age > 18 yr) patients undergoing emergent or elective spine surgery with 3 time-specific cohorts: before rollout of our institution's nPDT-CHG program (2006-2010), during rollout (2011-2014) and after rollout (2015-2019)...
2023: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/37882597/implementation-of-a-colorectal-surgical-site-infection-prevention-bundle-and-checklist-a-quality-improvement-project
#7
JOURNAL ARTICLE
Carrie White, Sarah Kurtz, Leandra Lusk, Brigitte Wilson, Vickie Britton, Karen Hayden, Sarah Hunt, Jennifer Hyland, William Kittrell, Jason Maddox, Ashley Tanner, Valerie Tucker
After noting an elevated surgical site infection rate in 2019 associated with colorectal surgeries, leaders at two Central Virginia health system hospitals convened an interdisciplinary team to audit current practices and research infection prevention strategies. After identifying a lack of standardization in care processes for colorectal surgery patients and reviewing the literature on colorectal bundles, the team created a bundle focusing on the use of antibiotics, chlorhexidine gluconate wipes or baths, separate closing instrument trays, nasal decolonization, bowel preparation, and maintaining patient normothermia...
November 2023: AORN Journal
https://read.qxmd.com/read/37875062/estimation-of-the-contribution-to-intraoperative-pathogen-transmission-from-bacterial-contamination-of-patient-nose-patient-groin-and-axilla-anesthesia-practitioners-hands-anesthesia-machine-and-intravenous-lumen
#8
JOURNAL ARTICLE
Franklin Dexter, Randy W Loftus
BACKGROUND: Earlier studies showed net cost saving from anesthesia practitioners' use of a bundle of infection prevention products, with feedback on monitored Staphylococcus aureus intraoperative transmission. ESKAPE pathogens also include Enterococcus and gram-negative pathogens: Klebsiella, Acinetobacter, Pseudomonas, and Enterobacter. We evaluated whether bacterial contamination of patient nose, patient groin and axilla, anesthesia practitioners' hands, anesthesia machine, and intravenous lumen all contribute meaningfully to ESKAPE pathogen transmission within anesthesia work areas...
October 22, 2023: Journal of Clinical Anesthesia
https://read.qxmd.com/read/37565083/biocidal-effects-of-a-wipe-down-procedure-using-common-veterinary-cleansers-on-microbial-burden-within-working-canine-exterior-coats
#9
JOURNAL ARTICLE
Erin B Perry, Dakota R Discepolo, Stephen Y Liang, Maurnice Scott, Kyleigh Williamson, Kelly S Bender
INTRODUCTION: Recent work demonstrating reduction of aerosolized contamination via a wipe-down procedure using common veterinary antiseptics offers promise regarding health concerns associated with cross-contamination from working canines to humans. While mechanical reduction can be achieved via a wipe-down procedure, the biocidal impact on flora within the exterior coat is unknown. METHODOLOGY: This study assessed the biocidal impact of antiseptics on the exterior bacterial community of the canine...
2023: Frontiers in Veterinary Science
https://read.qxmd.com/read/37355097/addressing-an-increase-in-surgical-site-infections-during-the-covid-19-pandemic-identifying-opportunities-during-a-chaotic-time
#10
JOURNAL ARTICLE
Traci A Plummer, Jordan A Zepeda, Sara M Reese
BACKGROUND: Health care systems saw increases in device-associated infections and decreases in surgical site infections (SSI) during the COVID-19 pandemic. However, following an increase in SSIs, an acute care hospital assessed the risk and preventative factors of SSIs among patients. METHODS: A retrospective cohort study on surgeries performed between January 2020 and September 2021 analyzed associations of SSI with risk and preventive factors utilizing χ2 , t-tests, and odds ratios...
June 22, 2023: American Journal of Infection Control
https://read.qxmd.com/read/37233145/shorter-scrubbing-drying-times-preferred-for-needleless-connect-or-disinfecting
#11
JOURNAL ARTICLE
Karen Rosenberg
According to this study: Comparing three different products for disinfecting needleless connectors showed that all were more effective than sterile water, but nurses preferred using chlorhexidine gluconate with isopropyl alcohol wipes.
June 1, 2023: American Journal of Nursing
https://read.qxmd.com/read/37212678/bacterial-colonisation-and-the-effect-of-a-cleaning-regime-on-ipad-patient-side-electronic-devices-used-in-a-veterinary-healthcare-setting
#12
JOURNAL ARTICLE
Maria Zurita, Matthew Garland, Tony Ryan
OBJECTIVES: This study aimed to determine the prevalence of clinically relevant bacteria on the surface of hospital-issued iPads and to assess the effectiveness and residual effect of a new cleaning regime using 70% alcohol and 2% chlorhexidine wipes. METHODS: Hospital-issued iPads were swabbed to determine the presence of clinically relevant organisms. The iPads were wiped using 70% alcohol and 2% chlorhexidine. Further samples were taken 5 mins, 6 h and 12 h after implementation of the cleaning regime...
May 2023: Journal of Feline Medicine and Surgery
https://read.qxmd.com/read/37154899/a-novel-sacral-neuromodulation-protocol-is-associated-with-reduction-in-removal-for-device-infection
#13
JOURNAL ARTICLE
Colin Goudelocke, Hayden Hill, Nicholas Major, Anastasia Couvaras, Amy Long
INTRODUCTION AND HYPOTHESIS: Sacral neuromodulation (SNM) has been established as an effective third-line therapy for non-obstructive urinary retention and urinary urgency-frequency syndrome. Device infection, ranging from 2-10%, is a severe complication usually necessitating device explanation. This study sought to demonstrate an infection protocol founded upon established device implantation risk factors and novel approaches to reduce the incidence of device infection, while maintaining good antibiotic stewardship following best practice statements...
May 8, 2023: International Urogynecology Journal
https://read.qxmd.com/read/37000078/impact-of-oral-care-modalities-on-the-incidence-of-ventilator-associated-pneumonia-in-the-intensive-care-unit-a-meta-analysis
#14
JOURNAL ARTICLE
Li-Sang Fu, Li-Mei Zhu, Yuan-Ping Yang, Ling Lin, Li-Qun Yao
BACKGROUND: At present, evidence of the role of oral hygiene in ICU-related pneumonia is rare. The study aimed to evaluate the effectiveness of toothbrush-based oral care in preventing ventilator-associated pneumonia (VAP) in patients with mechanical ventilation in the ICU. METHODS: Ten databases were searched for randomized controlled trials (RCTs) evaluating toothbrush-based oral care for preventing VAP in patients with mechanical ventilation in ICU. Quality assessment and data extraction were independently performed by 2 researchers...
March 31, 2023: Medicine (Baltimore)
https://read.qxmd.com/read/36873732/innovative-compounds-to-reduce-%C3%AE-d-glucans-endotoxin-and-allergens-newly-discovered-on-smartphones
#15
JOURNAL ARTICLE
Hana B Ruran, Lily Tourigny, Peter S Thorne, Nervana Metwali
BACKGROUND: Eight-four percent of people own smartphones and view them 14 billion times daily, making them potential vectors for environmental hazards such as allergens, β -D-glucans (BDGs), and endotoxin. Whether these toxins are prevalent and the effectiveness of cleaning solutions targeting these agents on smartphones have not been studied. OBJECTIVE: We sought to determine (1) whether phones are reservoirs of allergen, endotoxin, and BDGs and (2) if present, whether their levels can be effectively reduced by using specific cleaning methods...
February 2023: J Allergy Clin Immunol Glob
https://read.qxmd.com/read/36821410/techniques-for-decreasing-bacterial-load-for-open-shoulder-surgery
#16
JOURNAL ARTICLE
Eric J Panther, Kevin A Hao, Jonathan O Wright, Jennifer J Schoch, Alaina S Ritter, Joseph J King, Thomas W Wright, Bradley S Schoch
»: Benzoyl peroxide (BPO) 5% has been shown to reduce Cutibacterium acnes load on the skin. BPO 5% with miconazole nitrate (MN) 2% may be beneficial, whereas BPO 5% with clindamycin cream 1% to 1.2% does not seem to have additive effects when compared with BPO 5% alone. Chlorhexidine gluconate solutions reduce the total bacterial load on the skin, but do not seem to have a significant effect on C. acnes. »: ChloraPrep seems to be the best surgical skin preparation to decrease overall positive skin cultures...
November 1, 2022: JBJS Reviews
https://read.qxmd.com/read/36779575/effect-of-daily-chlorhexidine-bathing-on-reducing-infections-caused-by-multidrug-resistant-organisms-in-intensive-care-unit-patients-a-semiexperimental-study-with-parallel-controls
#17
JOURNAL ARTICLE
Wenzhi Huang, Fu Qiao, Lin Cai, Zhiyong Zong, Wei Zhang
OBJECTIVE: To assess the effectiveness of daily bathing by chlorhexidine bathing on multidrug-resistant organisms in ICU, especially on carbapenem-resistant Acinetobacter baumannii (CRAB), carbapenem-resistant Pseudomonas aeruginosa (CRPA), and carbapenem-resistant Enterobacteriaceae (CRE). METHODS: Semiexperimental study which employed both precontrols and a parallel control was conducted. In the intervention period (from July 1 to December 31, 2016), strengthened infection control measures and daily bathing with 2% CHG-impregnated wipes once daily was performed in the ICU...
February 13, 2023: Journal of Evidence-based Medicine
https://read.qxmd.com/read/36776438/cognitive-status-predicts-preoperative-instruction-compliance
#18
JOURNAL ARTICLE
Yasuko Mano, Porus Mistry, Khoa Tran, Benjamin Wright, Cristin Malekyan, Tatyana Gurvich, Carolyn Kaloostian, Arash Motamed, Justyne Decker
The most common postoperative complication for older adults is perioperative neurocognitive disorder (PNCD). Its greatest risk factor is preoperative cognitive impairment. Cognitive impairment also predicts higher likelihood of postoperative complications. While the cause of disparity in outcomes is likely multifactorial, the ability to correctly follow perioperative instructions may be one modifiable component. The purpose of this study was to determine whether cognitive impairment led to reduced preoperative instruction compliance and if so, identify barriers and enact a tailored care-plan to close the gap...
2023: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/36566648/the-efficacy-of-multifaceted-versus-single-anesthesia-work-area-infection-control-measures-and-the-importance-of-surgical-site-infection-follow-up-duration
#19
JOURNAL ARTICLE
Franklin Dexter, Jeremiah R Brown, Russell T Wall, Randy W Loftus
BACKGROUND: Earlier a randomized trial showed efficacy of a multifaceted intervention approach for reducing surgical site infection: hand hygiene, vascular care, environmental cleaning, patient decolonization (nasal povidone iodine, chlorhexidine wipes), with feedback on pathogen transmission. The follow-up prospective observational study showed effectiveness when applied to all operating rooms of an inpatient surgical suite. In practice, many organizations will at baseline not be using conditions equivalent to the control groups but instead functionally have had ongoing a single intervention for infection control (e...
May 2023: Journal of Clinical Anesthesia
https://read.qxmd.com/read/36547232/quantifying-exposure-to-chlorhexidine-from-decontamination-of-peripheral-intravenous-injection-ports
#20
JOURNAL ARTICLE
Matthew A Doane, Christopher Kwong, Nicholas Proschogo
BACKGROUND: Annually, almost 2 billion peripheral intravenous cannulas (PIVCs) are placed worldwide. In response to concerns of infectious complications, chlorhexidine is increasingly utilised for maintenance decontamination of PIVC injection ports. Concomitantly, the allergenic potential of chlorhexidine exposures has been highlighted by several case reports, implicating it as a trigger when used for this seemingly innocuous process. Given how widespread this application is, elucidating potential chlorhexidine exposure is needed to gauge its risks and benefits...
March 2023: Acta Anaesthesiologica Scandinavica
keyword
keyword
51181
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.