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https://www.readbyqxmd.com/read/28302757/alteration-of-monoamine-receptor-activity-and-glucose-metabolism-in-paediatric-patients-with-anticonvulsant-induced-cognitive-impairment
#1
Yuankai Zhu, Jianhua Feng, Jianfeng Ji, Haifeng Hou, Lin Chen, Shuang Wu, Qing Liu, Qiong Yao, Peizhen Du, Kai Zhang, Qing Chen, Zexin Chen, Hong Zhang, Mei Tian
A landmark study from the Institute of Medicine (IOM) reported that the assessment of cognitive difficulties in children with epilepsy is timely and imperative. Anticonvulsant-induced cognitive impairment could influence the quality of life more than seizure itself in patients. Although monoaminergic system is involved in the regulation of cognitive process, its role in anticonvulsant-induced cognitive impairment remains unclear. Methods: To explore in vivo monoamine receptor binding activity in patients with anticonvulsant-induced cognitive impairment, each patient had PET imaging with both monoamine receptor binding agent, (11)C-N-methylspiperone ((11)C-NMSP), and glucose metabolic agent, (18)F-fluorodeoxyglucose ((18)F-FDG)...
March 16, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28300527/the-development-of-an-evacuation-protocol-for-patients-with-ventricular-assist-devices-during-a-disaster
#2
Katherine J Davis, Joseph Suyama, Jennifer Lingler, Michael Beach
Introduction Health care providers are on the forefront of delivering care and allocating resources during a disaster; however, very few are adequately trained to respond in these situations. Furthermore, there is a void in the literature regarding the specific care needs of patients with ventricular assist devices (VADs) in a disaster setting. This project aimed to develop an evidenced-based protocol to aid health care providers during the evacuation of patients with VADs during a disaster. METHODS: This is a qualitative study that used expert review, tabletop discussion, and a survey of health care professionals to develop and evaluate an evacuation protocol...
March 16, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28294098/come-on-using-intervention-mapping-to-help-healthy-pregnant-women-achieve-healthy-weight-gain
#3
Astrid Merkx, Marlein Ausems, Raymond de Vries, Marianne J Nieuwenhuijze
OBJECTIVE: Gaining too much or too little weight in pregnancy (according to Institute of Medicine (IOM) guidelines) negatively affects both mother and child, but many women find it difficult to manage their gestational weight gain (GWG). Here we describe the use of the intervention mapping protocol to design 'Come On!', an intervention to promote adequate GWG among healthy pregnant women. DESIGN: We used the six steps of intervention mapping: (i) needs assessment; (ii) formulation of change objectives; (iii) selection of theory-based methods and practical strategies; (iv) development of the intervention programme; (v) development of an adoption and implementation plan; and (vi) development of an evaluation plan...
March 15, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28288954/content-usability-and-utilization-of-plain-language-in-breast-cancer-mobile-phone-apps-a-systematic-analysis
#4
Tamar Ginossar, Sayyed Fawad Ali Shah, Andrew J West, Joshua M Bentley, Charlene A Caburnay, Matthew W Kreuter, Anita Y Kinney
BACKGROUND: Breast cancer is one of the leading contributors to preventable illness and death among women. Although mobile phone apps provide unprecedented opportunity to engage women along the cancer continuum, little is known about the availability, content, and usability of breast cancer mobile phone apps. OBJECTIVE: This study analyzed the content and adherence to literate design standards of all breast cancer-related apps available on the App Store and Google Play, as well as the relationship between their content, user ratings, and price...
March 13, 2017: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/28276596/impact-of-calcium-and-two-doses-of-vitamin-d-on-bone-metabolism-in-the-elderly-a-randomized-controlled-trial
#5
Maya Rahme, Sima-Lynn Sharara, Rafic Baddoura, Robert H Habib, Georges Halaby, Asma Arabi, Ravinder J Singh, Moustapha Kassem, Ziyad Mahfoud, Maha Hoteit, Rose T Daher, Darina Bassil, Karim El Ferkh, Ghada El-Hajj Fuleihan
The optimal dose of vitamin D to optimize bone metabolism in the elderly is unclear. We tested the hypothesis a vitamin D, at a dose higher than recommended by the Institute of Medicine (IOM), has a beneficial effect on bone remodeling and mass. In this double blind trial we randomized 257 overweight elderly subjects to receive 1000 mg of elemental calcium citrate/day, and the daily equivalent of 3,750IU/day or 600 IU/day of vitamin D3 for one year. The subjects' mean age was 71 ± 4 years, body mass index 30 ± 4 kg/m(2) , 55% were women, and 222 completed the 12-months follow-up...
March 9, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28275100/maternal-supplementation-with-small-quantity-lipid-based-nutrient-supplements-compared-with-multiple-micronutrients-but-not-with-iron-and-folic-acid-reduces-the-prevalence-of-low-gestational-weight-gain-in-semi-urban-ghana-a-randomized-controlled-trial
#6
Seth Adu-Afarwuah, Anna Lartey, Harriet Okronipa, Per Ashorn, Ulla Ashorn, Mamane Zeilani, Mary Arimond, Stephen A Vosti, Kathryn G Dewey
Background: It is unclear whether maternal supplementation with small-quantity lipid-based nutrient supplements (SQ-LNSs; 118 kcal/d) affects maternal weight.Objective: We compared several secondary anthropometric measures between 3 groups of women in the iLiNS (International Lipid-based Nutrient Supplements)-DYAD trial in Ghana.Methods: Women (n = 1320; <20 wk of gestation) were randomly assigned to receive 60 mg Fe + 400 μg folic acid/d (IFA), 18 vitamins and minerals/d [multiple micronutrients (MMNs)], or 20 g SQ-LNSs with 22 micronutrients/d (LNS) during pregnancy and a placebo (200 mg Ca/d), MMNs, or SQ-LNSs, respectively, for 6 mo postpartum...
March 8, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28238467/micronutrient-intake-adequacy-in-children-from-birth-to-8-years-data-from-the-childhood-obesity-project
#7
Marta Zaragoza-Jordana, Ricardo Closa-Monasterolo, Veronica Luque, Natàlia Ferré, Veit Grote, Berthold Koletzko, Ingrid Pawellek, Elvira Verduci, Alice ReDionigi, Jerzy Socha, Anna Stolarczyk, Pascale Poncelet, Déborah Rousseaux, Joaquin Escribano
BACKGROUND: In European countries, suboptimal intake has been reported for several micronutrients (as calcium, iron, zinc, vitamin B12, D and folate) in both adulthood and childhood. No studies to date have prospectively compiled nutrient intake from healthy children in different European countries using the same methodology. AIM: To describe the adequacy of micronutrient intake during the first eight years of life in children from 5 European countries. METHODS: Prospective observational trial analyzing data from the EU Childhood Obesity Project...
February 9, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28219392/meaning-and-barriers-to-quality-care-service-provision-in-child-and-adolescent-mental-health-services-qualitative-study-of-stakeholder-perspectives
#8
Nadzeya Svirydzenka, Pablo Ronzoni, Nisha Dogra
BACKGROUND: Defining quality in health presents many challenges. The Institute of Medicine (IOM) defined quality clinical care as care that is equitable, timely, safe, efficient, effective and patient centred. However, it is not clear how different stakeholders within a child and adolescent mental health service (CAMHS) understand and/or apply this framework. This project aims to identify key stakeholders" understanding of the meaning of quality in the context of CAMHS. METHOD: The study sample comprised of three groups: (i) patients and carers, (ii) CAMHS clinical staff, and (iii) commissioners (Total N = 24)...
February 20, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28215372/the-managing-epilepsy-well-network-advancing-epilepsy-self-management
#9
EDITORIAL
Martha Sajatovic, Barbara C Jobst, Ross Shegog, Yvan A Bamps, Charles E Begley, Robert T Fraser, Erica K Johnson, Dilip K Pandey, Rakale C Quarells, Peter Scal, Tanya M Spruill, Nancy J Thompson, Rosemarie Kobau
Epilepsy, a complex spectrum of disorders, affects about 2.9 million people in the U.S. Similar to other chronic disorders, people with epilepsy face challenges related to management of the disorder, its treatment, co-occurring depression, disability, social disadvantages, and stigma. Two national conferences on public health and epilepsy (1997, 2003) and a 2012 IOM report on the public health dimensions of epilepsy highlighted important knowledge gaps and emphasized the need for evidence-based, scalable epilepsy self-management programs...
March 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28213991/the-value-of-workforce-data-in-shaping-nursing-workforce-policy-a-case-study-from-north-carolina
#10
Erin P Fraher
BACKGROUND: In 2015, the Institute of Medicine's Committee for Assessing Progress on Implementing the Future of Nursing recommendations noted that little progress has been made in building the data infrastructure needed to support nursing workforce policy. PURPOSE: This article outlines a case study from North Carolina to demonstrate the value of collecting, analyzing, and disseminating state-level workforce data. METHODS: Data were derived from licensure renewal information gathered by the North Carolina Board of Nursing and housed at the North Carolina Health Professions Data System at the University of North Carolina at Chapel Hill...
November 1, 2016: Nursing Outlook
https://www.readbyqxmd.com/read/28213820/daily-marijuana-use-is-associated-with-missed-clinic-appointments-among-hiv-infected-persons-engaged-in-hiv-care
#11
Aaron M Kipp, Peter F Rebeiro, Bryan E Shepherd, Lauren Brinkley-Rubinstein, Megan Turner, Sally Bebawy, Timothy R Sterling, Todd Hulgan
We assessed the association between marijuana use and retention in HIV care through a retrospective cohort study of patients engaged in care at a large HIV clinic in 2011 and 2012. Two different retention outcomes were assessed: not meeting the Institute of Medicine's (IOM) retention definition (≥2 provider visits ≥90 days apart in a calendar year) and no-show visits. Any marijuana use and frequency of marijuana use were obtained from a substance use screening questionnaire administered at each clinic visit...
February 17, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28192259/impact-of-intraoperative-monitoring-during-elective-complex-spinal-fusions-%C3%A2-4-levels-on-30-day-complication-and-readmission-rates-a-single-institutional-study-of-643-adult-spinal-deformity-patients
#12
Aladine A Elsamadicy, Owoicho Adogwa, Emily Lydon, Gireesh Reddy, Rayan Kaakati, Amanda Sergesketter, Oren N Gottfried, Isaac O Karikari
OBJECTIVE: The aim of this study is to determine if there are differences in 30-day postoperative complication and readmission rates between spinal deformity patients undergoing complex spinal fusion with and without intraoperative monitoring. METHODS: The medical records of 643 adult spine deformity patients undergoing elective complex spinal fusion (≥4 levels) at a major academic institution from 2005 to 2015 were reviewed. We identified 122 (19%) cases that involved intraoperative monitoring (IOM) including EMG, SSEP, and/or TcMEP and 521 (81%) that did not (IOM: n=122; No-IOM: n=521)...
February 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28188554/disinfection-by-product-formation-during-chlor-am-ination-of-algal-organic-matters-aom-extracted-from-microcystis-aeruginosa-effect-of-growth-phases-aom-and-bromide-concentration
#13
Juxiang Chen, Naiyun Gao, Lei Li, Mingqiu Zhu, Jing Yang, Xian Lu, Yansen Zhang
Algae organic matter (AOM), including extracellular organic matter (EOM) and intracellular organic matter (IOM), has caused a series of problems to the water quality, among which formation of disinfection by-products (DBPs) during subsequent chlor(am)ination process was especially serious and concerned. This study characterized physicochemical properties of the EOM and IOM solution extracted from different growth phases of Microcystis aeruginosa and investigated the corresponding formation potential of DBPs during chlor(am)ination process...
February 10, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28178913/training-us-health-care-professionals-on-human-trafficking-where-do-we-go-from-here
#14
Clydette Powell, Kirsten Dickins, Hanni Stoklosa
Some 21 million adults and children are labor-trafficked or sex-trafficked through force, fraud, or coercion. In recognition of the interface between trafficking victims and the healthcare setting, over the last 10 years there has been a notable increase in training of health care professionals (HCPs) on human trafficking (HT) and its health implications. Many organizations have developed curricula and offered training in various clinical settings. However, methods and content of this education on trafficking vary widely, and there is little evaluation of the impact of the training...
2017: Medical Education Online
https://www.readbyqxmd.com/read/28160934/arthroscopic-quantification-of-syndesmotic-instability-in-a-cadaveric-model
#15
Ross Feller, Todd Borenstein, Amanda J Fantry, Roy Bradley Kellum, Jason T Machan, Florian Nickisch, Brad Blankenhorn
PURPOSE: To investigate whether arthroscopy or stress radiography can identify instability resulting from single-ligament injury of the ankle syndesmosis and to determine whether either modality is capable of differentiating between various levels of ligament injury. METHODS: Syndesmotic/deltoid ligament sectioning was performed in 10 cadaver legs. Arthroscopic evaluation and fluoroscopic stress testing were completed after each sectioning. In group 1 (n = 5), sectioning began with anteroinferior tibiofibular ligament (AITFL), then interosseous membrane (IOM), posteroinferior tibiofibular ligament (PITFL), and deltoid...
February 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28159128/high-weight-gain-during-pregnancy-increases-the-risk-for-emergency-caesarean-section-population-based-data-from-the-swedish-maternal-health-care-register-2011-2012
#16
Carin Nilses, Margareta Persson, Marie Lindkvist, Kerstin Petersson, Ingrid Mogren
OBJECTIVE: The aim was to investigate maternal background factors' significance in relation to risk of elective and emergency caesarean sections (CS) in Sweden. STUDY DESIGN: Population-based, retrospective, cross-sectional study. The Swedish Maternal Health Care Register (MHCR) is a national quality register that collects data on pregnancy, delivery and postpartum period. All women registered in MHCR 2011 to 2012 were included in the study sample (N = 178,716)...
March 2017: Sexual & Reproductive Healthcare: Official Journal of the Swedish Association of Midwives
https://www.readbyqxmd.com/read/28156506/supportive-oncology-collaborative-initial-impact-of-supportive-oncology-screening-and-care
#17
Lauren Allison Wiebe, Catherine Deamant, Amy Scheu, Betty Roggenkamp, Urjeet Patel, Pam Khosla, Patricia A Robinson, Frank J Penedo, James Gerhart, William Dale, Oana Cristina Danciu, Rosa Berardi, Christine B Weldon, Julia Rachel Trosman
180 Background: The Institute of Medicine (IOM) 2013 report recommends supportive oncology care from diagnosis through survivorship, to end of life. The Coleman Supportive Oncology Collaborative (CSOC) developed a city-wide plan to improve supportive oncology. Metrics derived from the Commission on Cancer (CoC), ASCO Quality Oncology Practice Initiative (ASCO-QOPI) and National Quality Forum (NQF) were used to assess the CSOC impact. METHODS: Medical records of consecutive cancer patients from 6 practice improvement cancer centers in Chicago (3 academic, 2 safety-net, 1 public) were reviewed for 2 periods: 2014 (n = 843) and Q1 of 2015 (n = 313)...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28156474/a-consolidated-screening-tool-for-supportive-oncology-needs-and-distress
#18
Lauren Allison Wiebe, Shelly S Lo, Catherine Deamant, Betty Roggenkamp, Urjeet Patel, Pam Khosla, Patricia A Robinson, Frank J Penedo, James Gerhart, Teresa Lillis, William Dale, Ana Gordon, Rajul Kothari, Rosa Berardi, Julia Rachel Trosman, Christine B Weldon
72 Background: The IOM 2013 Report recommends that supportive oncology care start at cancer diagnosis; the Commission on Cancer (CoC) standard 3.2 requires distress screening and indicated action. Screening tools are not standardized across institutions and often address only a portion of patients' supportive oncology needs. METHODS: A collaborative of 100+ clinicians, funded by The Coleman Foundation, developed a patient-centric consolidated screening tool based on validated instruments (NCCN Distress Problem List, PHQ-4, PROMIS) and IOM and CoC...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152822/the-value-of-secondary-pathology-review
#19
Tinisha L Mayo, Tracy E Spinks, Richard Cheney, Peiguo Chu, Harry S Cooper, Suzanne Dintzis, Hormoz Ehya, Christopher D Fletcher, Amy Gerwirtz, Anthony Martin Magliocco, Sue Ellen Martin, Andrew E Rosenberg, Andy Sherrod, Lee K Tan, Brent L Wood, Ronald Stewart Walters
6 Background: Improving the value of cancer care is a major focus for the Alliance of Dedicated Cancer Centers (ADCC). Looking to align with the Institute of Medicine's (IOM) initiative to "Develop and deploy approaches to identify, learn from, and reduce diagnostic errors and near misses in clinical practice," the ADCC implemented a study to examine the clinical impact of expert secondary pathology review. The goal of this project was to: 1) demonstrate the value of secondary review of outside pathological specimens by ADCC subspecialty pathologists in identifying significant errors that can potentially impact treatment; and 2) create an opportunity to improve patient cancer care...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152818/how-well-are-cancer-centers-addressing-supportive-oncology-needs
#20
Jennifer Carrie Obel, Catherine Deamant, Rosa Berardi, Patricia A Robinson, William Dale, Oana C Danciu, James Gerhart, Paramjeet Khosla, Urjeet Patel, Colleen Savory, Julia Rachel Trosman
96 Background: The IOM 2013 report recommends comprehensive supportive oncology care from diagnosis through survivorship to end of life. The Coleman Foundation supported a baseline assessment of supportive oncology care using key COC, ASCO-QOPI and NQF measures. METHODS: Data extracted from medical records at 6 Chicago cancer centers in 2014 (n = 843 patients), including stage I-III (n = 391) and stage IV solid tumor or refractory hematologic malignancy (n = 452). RESULTS: Fifty-four percent of patients had discussions on understanding of illness, 24% were informed of prognosis timeframe, and 5% had a documented healthcare power of attorney...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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