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https://www.readbyqxmd.com/read/27925328/screening-for-preeclampsia-in-the-first-trimester-the-usefulness-of-maternal-hemodynamics-and-bioimpedence-in-non-obese-patients
#1
Giulia Gagliardi, Grazia Maria Tiralongo, Damiano Lo Presti, Ilaria Pisani, Daniele Farsetti, Barbara Vasapollo, Gian Paolo Novelli, Angela Andreoli, Herbert Valensise
OBJECTIVE: To test if maternal hemodynamics, and bioimpedance, together with the Combined Screening (maternal history, biophysical and biochemical markers), are able to identify normotensive non-obese patients at risk for preeclampsia (PE) and/or intrauterine growth restriction (IUGR) in the first trimester of gestation. METHODS: 150 healthy nulliparous non-obese women (BMI<30Kg/m(2) ) were enrolled in the study in the first trimester of pregnancy and submitted to USCOM to detect hemodynamic parameters, bioimpedence to characterize body composition, and combined screening for preeclampsia (maternal history, biophysical and maternal biochemical markers)...
December 7, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27924355/avp-dynamically-increases-paracellular-na-permeability-and-transcellular-nacl-transport-in-the-medullary-thick-ascending-limb-of-henle-s-loop
#2
REVIEW
Nina Himmerkus, Allein Plain, Rita D Marques, Svenja R Sonntag, Alexander Paliege, Jens Leipziger, Markus Bleich
The medullary thick ascending limb of Henle's loop (mTAL) is crucial for urine-concentrating ability of the kidney. It is water tight and able to dilute the luminal fluid by active transcellular NaCl transport, fueling the counter current mechanism by increasing interstitial osmolality. While chloride is exclusively transported transcellularly, approx. 50% of sodium transport occurs via the paracellular route, driven by the lumen-positive transepithelial potential. Antidiuretic hormone (AVP) is known to increase active NaCl transport to support collecting duct water reabsorption...
December 6, 2016: Pflügers Archiv: European Journal of Physiology
https://www.readbyqxmd.com/read/27920787/interactive-effects-of-elevated-co2-and-water-stress-on-physiological-traits-and-gene-expression-during-vegetative-growth-in-four-durum-wheat-genotypes
#3
Susan Medina, Rubén Vicente, Amaya Amador, José Luis Araus
The interaction of elevated [CO2] and water stress will have an effect on the adaptation of durum wheat to future climate scenarios. For the Mediterranean basin these scenarios include the rising occurrence of water stress during the first part of the crop cycle. In this study, we evaluated the interactive effects of elevated [CO2] and moderate to severe water stress during the first part of the growth cycle on physiological traits and gene expression in four modern durum wheat genotypes. Physiological data showed that elevated [CO2] promoted plant growth but reduced N content...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27919312/lessons-from-an-outbreak-of-legionnaires-disease-on-a-hematology-oncology-unit
#4
Louise K Francois Watkins, Karrie-Ann E Toews, Aaron M Harris, Sherri Davidson, Stephanie Ayers-Millsap, Claressa E Lucas, Brian C Hubbard, Natalia A Kozak-Muiznieks, Edward Khan, Preeta K Kutty
OBJECTIVES To define the scope of an outbreak of Legionnaires' disease (LD), to identify the source, and to stop transmission. DESIGN AND SETTING Epidemiologic investigation of an LD outbreak among patients and a visitor exposed to a newly constructed hematology-oncology unit. METHODS An LD case was defined as radiographically confirmed pneumonia in a person with positive urinary antigen testing and/or respiratory culture for Legionella and exposure to the hematology-oncology unit after February 20, 2014. Cases were classified as definitely or probably healthcare-associated based on whether they were exposed to the unit for all or part of the incubation period (2-10 days)...
December 6, 2016: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/27919026/hindered-cytoplasmic-diffusion-of-inositol-trisphosphate-restricts-its-cellular-range-of-action
#5
George D Dickinson, Kyle L Ellefsen, Silvina Ponce Dawson, John E Pearson, Ian Parker
The range of action of intracellular messengers is determined by their rates of diffusion and degradation. Previous measurements in oocyte cytoplasmic extracts indicated that the Ca(2+)-liberating second messenger inositol trisphosphate (IP3) diffuses with a coefficient (~280 μm(2) s(-1)) similar to that in water, corresponding to a range of action of ~25 μm. Consequently, IP3 is generally considered a "global" cellular messenger. We reexamined this issue by measuring local IP3-evoked Ca(2+) puffs to monitor IP3 diffusing from spot photorelease in neuroblastoma cells...
November 8, 2016: Science Signaling
https://www.readbyqxmd.com/read/27918984/hypertension-among-adults-exposed-to-drinking-water-arsenic-in-northern-chile
#6
Emily M Hall, Johanna Acevedo, Francisca González López, Sandra Cortés, Catterina Ferreccio, Allan H Smith, Craig M Steinmaus
BACKGROUND: A growing number of studies have identified an association between exposure to inorganic arsenic and hypertension. However, results have not been consistent across studies. Additional studies are warranted, given the global prevalence of both arsenic exposure and morbidity attributable to hypertension. METHODS: We analyzed data collected from October 2007-December 2010 for a population-based cancer case-control study in northern Chile. Data included lifetime individual arsenic exposure estimates and information on potential confounders for a total of 1266 subjects...
December 2, 2016: Environmental Research
https://www.readbyqxmd.com/read/27918021/photo-catalyzed-surface-hydrolysis-of-iridium-iii-ions-on-semiconductors-a-facile-method-for-the-preparation-of-semiconductor-irox-composite-photoanodes-toward-oxygen-evolution-reaction
#7
Qingyong Wu, Di Xu, Ning Xue, Tengyi Liu, Min Xiang, Peng Diao
We previously reported that the hydrolysis of Ir(3+) in homogeneous solution could be triggered by irradiation with light whose energy was larger than a threshold value. In this work, we demonstrated that, by introducing Fe2O3 particles into solution, the incident light energy-restriction for the photo-catalyzed hydrolysis could be broken and the hydrolysis occurred at the Fe2O3/solution interface. The photo-generated holes on the Fe2O3 surface played a key role in oxidizing Ir(iii) to Ir(iv) species and triggered the deposition of IrOx...
December 5, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27917187/integrating-physiology-and-architecture-in-models-of-fruit-expansion
#8
Mikolaj Cieslak, Ibrahim Cheddadi, Frédéric Boudon, Valentina Baldazzi, Michel Génard, Christophe Godin, Nadia Bertin
Architectural properties of a fruit, such as its shape, vascular patterns, and skin morphology, play a significant role in determining the distributions of water, carbohydrates, and nutrients inside the fruit. Understanding the impact of these properties on fruit quality is difficult because they develop over time and are highly dependent on both genetic and environmental controls. We present a 3D functional-structural fruit model that can be used to investigate effects of the principle architectural properties on fruit quality...
2016: Frontiers in Plant Science
https://www.readbyqxmd.com/read/27917170/isolation-and-characterization-of-acinetobacter-baumannii-recovered-from-campylobacter-selective-medium
#9
Dinesh M Fernando, Izhar U H Khan, Rakesh Patidar, David R Lapen, Guylaine Talbot, Edward Topp, Ayush Kumar
Acinetobacter baumannii, a Gram-negative opportunistic pathogen, is known to cause multidrug resistant infections. This organism has primarily been isolated from clinical environments and its environmental reservoirs remain largely unknown. In the present study, we recovered seven isolates of A. baumannii growing under conditions selective for Campylobacter spp. (microaerophilic at 42°C and in the presence of antibiotics) from dairy cattle manure storage tank or surface water impacted by livestock effluents...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27915174/molecular-and-physiological-responses-of-iranian-perennial-ryegrass-as-affected-by-trinexapac-ethyl-paclobutrazol-and-abscisic-acid-under-drought-stress
#10
Mohammad Hossein Sheikh Mohammadi, Nematollah Etemadi, Mohammad Mehdi Arab, Mostafa Aalifar, Mostafa Arab, Mohammad Pessarakli
Drought stress is the major limiting factor which affects turfgrass management in area with restricted rainfall or irrigation water supply. Trinexapac ethyl (TE), Paclobutrazol (PAC) and Abscisic acid (ABA) are three plant growth regulators (PGRs) that are commonly used on turf species for increasing their tolerance to different environmental stresses such as drought. However, little is known about the impact of PGRs on stress tolerance of Iranian Perennial ryegrass (Lolium perenne). The present study was conducted to examine the visual and physiological changes of Iranian Perennial ryegrass in response to foliar application of TE, PAC, and ABA under drought stress conditions...
November 27, 2016: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/27909746/brain-glutamate-in-anorexia-nervosa-a-magnetic-resonance-spectroscopy-case-control-study-at-7-tesla
#11
Beata R Godlewska, Alexandra Pike, Ann L Sharpley, Agnes Ayton, Rebecca J Park, Philip J Cowen, Uzay E Emir
RATIONALE: Anorexia nervosa (AN) is a serious psychiatric disorder with high morbidity and mortality. There are no established pharmacological treatments and the neurobiology of the condition is poorly understood. Previous studies using magnetic resonance spectroscopy (MRS) have shown that AN may be associated with reductions in indices of brain glutamate; however, at conventional field strengths (≤3 T), it is difficult to separate glutamate from its precursor and metabolite, glutamine...
December 1, 2016: Psychopharmacology
https://www.readbyqxmd.com/read/27905160/improving-the-solubility-of-artificial-ligands-of-streptavidin-to-enable-more-practical-reversible-switching-of-protein-localization-in-cells
#12
Ryo Tachibana, Takuya Terai, Gaelle Boncompain, Shigeru Sugiyama, Nae Saito, Franck Perez, Yasuteru Urano
Chemical inducers that can control target protein localization in living cells are powerful tools to investigate dynamic biological systems. We recently reported the "retention using selective hook" (RUSH) system for reversible localization change of proteins of interest by addition/washout of small molecules called artificial ligands of streptavidin (ALiS). However, the utility of previously developed ALiS is restricted by limited solubility in water. Here, we overcome this problem by X-ray crystal structure-guided design of a more soluble ALiS derivative (ALiS-3), which retains sufficient streptavidin-binding affinity for use in the RUSH system...
November 30, 2016: Chembiochem: a European Journal of Chemical Biology
https://www.readbyqxmd.com/read/27902456/long-term-caloric-restriction-in-apoe-deficient-mice-results-in-neuroprotection-via-fgf21-induced-ampk-mtor-pathway
#13
Claire Rühlmann, Tjark Wölk, Tobias Blümel, Laura Stahn, Brigitte Vollmar, Angela Kuhla
Caloric restriction (CR) decelerates the aging process, extends lifespan and exerts neuroprotective effects in diverse species by so far unknown mechanisms. Based on known neuroprotective effects of fibroblastic growth factor 21 (Fgf21) we speculate that CR upregulates Fgf21, which phosphorylates neuronal AMP-activated protein kinase (AMPK), leading to a decrease of mammalian target of rapamycin (mTOR) signaling activity and an inhibition of tau-hyperphosphorylation. This in turn reduces the formation of neurofibrillary tangles, a neuropathological hallmark of Alzheimer´s disease...
November 29, 2016: Aging
https://www.readbyqxmd.com/read/27901497/curcumin-carrying-nanoparticles-prevent-ischemia-reperfusion-injury-in-human-renal-cells
#14
Yong Xu, Ning Hu, Wei Jiang, Hong-Fang Yuan, Dong-Hui Zheng
Renal ischemia-reperfusion injury (IRI) is a major complication in clinical practice. However, despite its frequency, effective preventive/treatment strategies for this condition are scarce. Curcumin possesses antioxidant properties and is a promising potential protective agent against renal IRI, but its poor water solubility restricts its application. In this study, we constructed curcumin-carrying distearoylphosphatidylethanolamine-polyethylene glycol nanoparticles (Cur-NPs), and their effect on HK-2 cells exposed to IRI was examined in vitro...
November 25, 2016: Oncotarget
https://www.readbyqxmd.com/read/27901304/predicting-occurrence-of-juvenile-shark-habitat-to-improve-conservation-planning
#15
Beverly Z L Oh, Ana M M Sequeira, Mark G Meekan, Jonathan L W Ruppert, Jessica J Meeuwig
Fishing and habitat degradation have increased the extinction risk of sharks, and conservation strategies recognize that survival of juveniles is critical for the effective management of shark populations. Despite the rapid expansion of marine protected areas (MPAs) globally, the paucity of shark-monitoring data on large scales (100s-1000s km) means that the effectiveness of MPAs in halting shark declines remains unclear. Using data collected by baited remote underwater video systems (BRUVS) in northwestern Australia, we developed generalized linear models to elucidate the ecological drivers of the occurrence of juvenile shark habitat...
November 30, 2016: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/27899319/cost-effective-raspberry-pi-based-radio-frequency-identification-tagging-of-mice-suitable-for-automated-in-vivo-imaging
#16
Federico Bolaños, Jeff M LeDue, Timothy H Murphy
BACKGROUND: Automation of animal experimentation improves consistency, reduces potential for error while decreasing animal stress and increasing well-being. Radio frequency identification (RFID) tagging can identify individual mice in group housing environments enabling animal-specific tracking of physiological parameters. NEW METHOD: We describe a simple protocol to radio frequency identification (RFID) tag and detect mice. RFID tags were injected sub-cutaneously after brief isoflurane anesthesia and do not require surgical steps such as suturing or incisions...
November 27, 2016: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27898114/vibration-induced-emission-vie-for-imaging-amyloid-%C3%AE-fibrils
#17
Wei-Tao Dou, Wei Chen, Xiao-Peng He, Jianhua Su, He Tian
This paper discusses the use of N,N'-disubstituted-dihydrodibenzo[a,c]phenazines with typical Vibration-Induced-Emission (VIE) properties for imaging amyloid β (Aβ) fibrils, which are a signature of neurological disorders such as Alzheimer's disease. A water-soluble VIEgen with a red fluorescence emission shows a pronounced, blue-shifted emission with Aβ peptide monomers and fibrils. The enhancement in blue fluorescence can be ascribed to the restriction of the molecular vibration by selectively binding to Aβ...
November 29, 2016: Faraday Discussions
https://www.readbyqxmd.com/read/27895434/bay-41-2272-treatment-improves-acetylcholine-induced-aortic-relaxation-in-l-name-hypertensive-rats
#18
Shahid Prawez, Azad Ahmad Ahanger, Thakur Uttam Singh, Santosh Kumar Mishra, Souvendra Nath Sarkar, Dinesh Kumar
Hypertension, an emerging problem of recent era, and many pathophysiological factors are participating to produce the disease. Nitric oxide (NO) is an important constituent to ameliorate hypertensive condition. Inhibition of endogenous NO synthase by L-N(G)-Nitroarginine methyl ester (L-NAME) was responsible for generating hypertension in rats. BAY 41-2272 (5-cyclopropyl-2-[1-(2-fluoro-benzyl)-1H-pyrazolo[3,4-b]pyridine-3-yl]-pyrimidin-4-ylamine), a soluble guanylyl cyclase activator, restricts rise of blood pressure and shows cardioprotective activity...
December 2016: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/27891456/effect-of-salivary-ph-on-color-stability-of-different-flowable-composites-a-prospective-in-vitro-study
#19
Renu Batra, Pratik Kataria, Sonali Kapoor
INTRODUCTION: Scientifically and clinically there has been lot of development in the field of aesthetic dentistry. However, there is limited or restricted information regarding the color stability of flowable composite materials. AIM: The aim of this study was to evaluate the spectrophotometric color stability of three different flowable composite materials with respect to three different pH of saliva. MATERIALS AND METHODS: The study included 90 different samples...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27890779/fast-triple-spin-echo-dixon-ftsed-sequence-for-water-and-fat-imaging
#20
Radim Korinek, Karel Bartusek, Zenon Starcuk
A number of 'Dixon' techniques based on fast spin echo (FSE) sequence have been proposed and successfully used in many branches of medicine. Some require only one scan, but most of them need multiple scans and long scan times. This article describes a new fast triple-spin-echo Dixon (FTSED) technique suitable for ultra-high field MRI, in which three specific time shifts are introduced in the echo train; thus, three images with defined water-fat phase-differences (0, π, 2π) are encoded in the phase of the acquired images without extreme restrictions upon the echo duration...
November 24, 2016: Magnetic Resonance Imaging
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