keyword
MENU ▼
Read by QxMD icon Read
search

Ca19-9

keyword
https://www.readbyqxmd.com/read/28918613/predicting-time-to-reflux-of-children-with-antenatal-hydronephrosis-a-competing-risks-approach
#1
Maryam Nazemipour, Abdol-Mohammad Kajbafzadeh, Kazem Mohammad, Abbas Rahimi Foroushani, Mahmood Mahmoudi
The aim of this study was describing methodological aspects and applying a trivariate Weibull survival model using the competing risks concept to predict time to occurrence different types of reflux (unilateral (left, right) or bilateral) in children with antenatal hydronephrosis. Data from 333 children in Pediatric Urology Research Center of Children's Hospital Medical Center, affiliated with Tehran University of Medical Sciences was used. The effect of some demographic and clinical factors on child's reflux was studied...
July 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28915662/cbl-b-predicts-postoperative-survival-in-patients-with-resectable-pancreatic-ductal-adenocarcinoma
#2
Qian Dong, Yuteng Ma, Yao Zhang, Xiujuan Qu, Zhi Li, Yafei Qi, Yunpeng Liu, Ce Li, Kai Li, Xianghong Yang, Xiaofang Che
Casitas B-lineage lymphoma b (Cbl-b) is a ubiquitin-protein ligase and a signal transducing adaptor protein involved in immune regulation, and it may be involved in the development and progression of cancer. We investigated the association between Cbl-b expression and prognosis in patients with resectable pancreatic ductal adenocarcinoma (PDAC). The clinicopathological characteristics and survival data of 134 patients with surgery for PDAC between January 2009 and February 2012 were retrospectively evaluated, and Cbl-b expression was assayed by immunohistochemical staining...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28903421/development-and-validation-of-a-preoperative-prediction-model-for-colorectal-cancer-t-staging-based-on-mdct-images-and-clinical-information
#3
Sha Sa, Jing Li, Xiaodong Li, Yongrui Li, Xiaoming Liu, Defeng Wang, Huimao Zhang, Yu Fu
OBJECTIVES: This study aimed to establish and evaluate the efficacy of a prediction model for colorectal cancer T-staging. RESULTS: T-staging was positively correlated with the level of carcinoembryonic antigen (CEA), expression of carbohydrate antigen 19-9 (CA19-9), wall deformity, blurred outer edges, fat infiltration, infiltration into the surrounding tissue, tumor size and wall thickness. Age, location, enhancement rate and enhancement homogeneity were negatively correlated with T-staging...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28903321/alu-based-cell-free-dna-a-novel-biomarker-for-screening-of-gastric-cancer
#4
Chen Qian, Shaoqing Ju, Jing Qi, Jianmei Zhao, Xianjuan Shen, Rongrong Jing, Juan Yu, Li Li, Yingjuan Shi, Lurong Zhang, Zhiwei Wang, Hui Cong
Gastric cancer (GC) is the fourth most common cancer and the second major cause of cancer-related deaths worldwide. In our previous study, a novel and sensitive method for quantifying cell-free DNA (CFD) in human blood was established and tested for its ability to predict patients with tumor. We want to investigate CFD expression in the sera of GC patients in an attempt to explore the clinical significance of CFD in improving the early screening of GC and monitoring GC progression by the branched DNA (bDNA)-based Alu assay...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28900990/-prognostic-value-of-carcinoembryonic-antigen-alpha-fetoprotein-carbohydrate-antigen-125-and-carbohydrate-antigen-19-9-in-gastroenteropancreatic-neuroendocrine-neoplasms
#5
Luohai Chen, Yu Zhang, Minhu Chen, Jie Chen
OBJECTIVE: To study the rate of elevated common biomarkers of digestive tumors, including carcinoembryonic antigen (CEA), alpha fetoprotein (AFP), carbohydrate antigen 125 (CA125) and carbohydrate antigen 19-9 (CA19-9), in gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) and their prognostic values in GEP-NEN. METHODS: Clinicopathological data of patients with GEP-NEN treated in The First Affiliated Hospital, Sun Yat-sen University from January 2011 to December 2016 were retrospectively studied...
September 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28898797/scarless-surgery-for-a-huge-liver-cyst-a-case-report
#6
Hiroyuki Kashiwagi, Jun Kawachi, Naoko Isogai, Masanori Ishii, Katsunori Miyake, Rai Shimoyama, Ryota Fukai, Hidemitsu Ogino
INTRODUCTION: Symptomatic or complicated liver cysts sometimes require surgical intervention and laparoscopic fenestration is the definitive treatment for these cysts. We performed minimally invasive surgery, hybrid natural orifice transluminal endoscopic surgery (NOTES) without scarring, for a huge liver cyst. PRESENTATION OF CASE: An 82-year-old female presented with a month-long history of right upper abdominal pain. We diagnosed her condition as a huge liver cyst by morphological studies...
September 1, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28894584/serum-human-epididymis-protein-4-levels-in-colorectal-cancer-patients
#7
Yasemi N Kemal, Guzi N Demirag, Abdulkeri M Bedir, Leman Tomak, Murat Derebey, Di Lek Erdem, Ufuk Gör, Idris Yücel
Tumour markers are widely used for the diagnosis, staging and monitoring of colorectal cancer (CRC) patients in clinical practice. Carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) are the most frequently used biomarkers in CRC patients. A number of studies have recently investigated the presence of human epididymis protein 4 (HE4) overexpression in certain cancer types. Its significance in ovarian and endometrial cancer has been well-demonstrated. The aim of the present study was to evaluate the significance of serum HE4 levels in CRC patients...
September 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28890823/does-lymphocyte-to-monocyte-ratio-before-during-or-after-definitive-chemoradiation-for-locally-advanced-pancreatic-cancer-predict-for-clinical-outcomes
#8
Irene Giacomelli, Daniele Scartoni, Homan Mohammadi, William F Regine, Michael D Chuong
BACKGROUND: Elevated pre-treatment lymphocyte (L) to monocyte (M) ratio (LMR) in peripheral blood has been suggested to correlate with improved survival in some malignancies, but data in the context of pancreatic cancer (PC) is limited. The aim of this study was to evaluate the prognostic significance of LMR before, during and after definitive chemoradiotherapy (CRT) for locally advanced pancreatic cancer (LAPC). METHODS: We retrospectively reviewed 57 patients with LAPC treated with definitive CRT at a single institution from 2005 to 2013...
August 2017: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/28883702/doublecortin-and-cam-kinase-like-1-as-an-independent-prognostic-factor-in-patients-with-resected-pancreatic-carcinoma
#9
Kohei Nishio, Kenjiro Kimura, Ryosuke Amano, Bunzo Nakata, Sadaaki Yamazoe, Go Ohira, Kotaro Miura, Naoki Kametani, Hiroaki Tanaka, Kazuya Muguruma, Kosei Hirakawa, Masaichi Ohira
AIM: To elucidate the effect of expression of doublecortin and CaM kinase-like-1 (DCLK1) in patients with pancreatic ductal adenocarcinoma (PDAC). METHODS: Tumor specimens were obtained from 136 patients with pancreatic cancer who had undergone resection without preoperative therapy between January 2000 and December 2013 at the Department of Surgical Oncology, Osaka City University. The resected specimens were analyzed for associations with clinicopathological data, including DCLK1 expression, epithelial mesenchymal transition (EMT) marker expression, and cancer stem cell (CSC) marker expression...
August 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28871520/visceral-adiposity-and-sarcopenic-visceral-obesity-are-associated-with-poor-prognosis-after-resection-of-pancreatic-cancer
#10
Shinya Okumura, Toshimi Kaido, Yuhei Hamaguchi, Atsushi Kobayashi, Hisaya Shirai, Siyuan Yao, Shintaro Yagi, Naoko Kamo, Etsuro Hatano, Hideaki Okajima, Kyoichi Takaori, Shinji Uemoto
BACKGROUND: Visceral fat accumulation and muscle depletion have been identified as poor prognostic factors for various cancers. However, the significance of visceral adiposity and sarcopenic visceral obesity on outcomes after resection of pancreatic cancer remains unclear. METHODS: A retrospective analysis of 301 patients who underwent resection for localized pancreatic cancer between 2004 and 2015 was performed. The extent of visceral adiposity [visceral to subcutaneous adipose tissue area ratio (VSR)] and visceral obesity [visceral fat area (VFA)] were measured on preoperative computed tomography images, together with skeletal muscle index (SMI) and muscle attenuation (MA)...
September 5, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28871458/percutaneous-irreversible-electroporation-combined-with-allogeneic-natural-killer-cell-immunotherapy-for-patients-with-unresectable-stage-iii-iv-pancreatic-cancer-a-promising-treatment
#11
Mao Lin, Shuzhen Liang, Xiaohua Wang, Yinqing Liang, Mingjie Zhang, Jibing Chen, Lizhi Niu, Kecheng Xu
PURPOSE: This study was attempted to investigate the safety and clinical efficacy of percutaneous irreversible electroporation combined with allogeneic natural killer cell therapy for treating stage III/IV pancreatic cancer, evaluate median progression-free survival (PFS), and overall survival (OS). METHODS: Between March 2016 and February 2017, we enrolled 67 patients who met the enrollment criteria. According to the latest NCCN Guidelines, the patients were divided into stage III (35 patients, 16 patients received only irreversible electroporation (IRE) and 19 patients received IRE-NK: 8 patients underwent one course NK and 11 patients underwent ≥3 courses) and stage IV (32 patients, 14 patients received only IRE and 18 patients received IRE-NK: 8 patients underwent one course NK and 10 patients underwent ≥3 courses)...
September 4, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28866662/serum-ca19-9-response-is-an-early-predictive-marker-of-efficacy-of-regorafenib-in-refractory-metastatic-colorectal-cancer
#12
Azusa Komori, Hiroya Taniguchi, Satoshi Hamauchi, Toshiki Masuishi, Yosuke Kito, Yukiya Narita, Takahiro Tsushima, Makoto Ishihara, Akiko Todaka, Tsutomu Tanaka, Tomoya Yokota, Shigenori Kadowaki, Nozomu Machida, Takashi Ura, Akira Fukutomi, Masashi Ando, Yusuke Onozawa, Masahiro Tajika, Hirofumi Yasui, Kei Muro, Keita Mori, Kentaro Yamazaki
PURPOSE: Regorafenib improves survival in chemorefractory metastatic colorectal cancer (mCRC) patients. However, regorafenib induces various adverse events (AEs) that often impair patients' quality of life. Identification of early predictive markers of the efficacy is warranted. METHODS: We retrospectively examined 146 consecutive mCRC patients who received regorafenib. Clinical parameters, including patient background, AEs, and changes in biochemical parameters until day 28, were evaluated to identify efficacy predictors...
September 2, 2017: Oncology
https://www.readbyqxmd.com/read/28858867/pretreatment-serum-carbohydrate-antigen-19-9-concentration-is-a-predictor-of-survival-of-patients-who-have-undergone-curative-resection-of-stage-iv-rectal-cancer
#13
Hisanori Miki, Takashi Akiyoshi, Atsushi Ogura, Toshiya Nagasaki, Tsuyoshi Konishi, Yoshiya Fujimoto, Satoshi Nagayama, Hisashi Noma, Akio Saiura, Yosuke Fukunaga, Masashi Ueno
BACKGROUND: To evaluate whether pretreatment carcinoembryonic antigen and carbohydrate antigen (CA)19-9 are useful predictors of survival in patients with stage IV rectal cancer who have undergone curative resection. METHODS: In this retrospective study, data on 73 patients who had undergone curative resection of stage IV rectal cancer were reviewed. Associations between various clinicopathological factors and survival outcomes were analyzed. RESULTS: According to univariate analysis, elevated pretreatment CA19-9 (p = 0...
September 1, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/28856862/gonadotrophin-releasing-hormone-agonist-combined-with-high-intensity-focused-ultrasound-ablation-for-adenomyosis-a-clinical-study
#14
Y Guo, H Duan, J Cheng, Y Zhang
OBJECTIVES: This study was to investigate the clinical efficacy of a gonadotrophin-releasing hormone agonist (GnRH-a) combined with high-intensity focused ultrasound (HIFU) ablation treatment for adenomyosis. DESIGN: A non-randomized prospective study. SETTING: Gynaecological Minimally Invasive Centre in a single hospital. POPULATION: Patients with adenomyosis. METHODS: Seventy-nine patients with adenomyosis were enrolled, including 55 patients in the control group treated with only HIFU and 24 patients in the study group treated with GnRH-a combined with HIFU...
August 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28855992/clinical-significance-of-serum-anti-p53-antibody-expression-following-curative-surgery-for-colorectal-cancer
#15
Kensuke Kumamoto, Hideyuki Ishida, Koki Kuwabara, Kunihiko Amano, Noriyasu Chika, Norimichi Okada, Tomonori Ohsawa, Youichi Kumagai, Keiichiro Ishibashi
The aim of the present study was to investigate the usefulness of serum anti-p53 antibody (Ap53Ab) measurement for the diagnosis of colorectal cancer (CRC), and the clinical significance of the association between Ap53Ab expression and survival rate. Ap53Ab, carcinoembryonic antigen (CEA) and carbohydrate antigen (CA)19-9 were measured by ELISA in 674 CRC patients and 115 healthy volunteers (control group). The half-life time of Ap53Ab and CEA was calculated. The association between positive Ap53Ab expression and clinicopathological characteristics, including survival rate, was analyzed...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28852317/pancreaticoduodenectomy-for-duodenal-papilla-carcinoma-a-single-centre-9-year-retrospective-study-of-112-patients-with-long-term-follow-up
#16
Pei-Long Lian, Yuan Chang, Xiu-Chun Xu, Zhen Zhao, Xian-Qiang Wang, Ke-Sen Xu
AIM: To retrospectively evaluate the factors that influence long-term outcomes of duodenal papilla carcinoma (DPC) after standard pancreaticoduodenectomy (SPD). METHODS: This is a single-centre, retrospective study including 112 DPC patients who had a SPD between 2006 and 2015. Associations between serum levels of CA19-9 and CEA and various clinical characteristics of 112 patients with DPC were evaluated by the χ(2) test and Fisher's exact test. The patients were followed-up every 3 mo in the first two years and at least every 6 mo afterwards, with a median follow-up of 60 mo (ranging from 4 mo to 168 mo)...
August 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28843358/brief-report-baseline-and-on-treatment-characteristics-of-serum-tumor-markers-in-stage-iv-oncogene-addicted-adenocarcinoma-of-the-lung
#17
Sinead A Noonan, Tejas Patil, Dexiang Gao, Gentry G King, Jessica R Thibault, Xian Lu, Paul A Bunn, Robert C Doebele, W Thomas Purcell, Anna E Barón, D Ross Camidge
INTRODUCTION: The role of serum tumor markers in the modern management of advanced non-small cell lung cancer remains poorly described. METHODS: A single center retrospective analysis of available CEA, CA125, CA19.9 and CA27.29 levels at baseline and on treatment in stage IV lung adenocarcinoma by oncogenic driver was conducted. RESULTS: 142 patients were analyzed (ALK=60, EGFR=50, ROS1=4 and KRAS=28). 82% of patients had at least one marker; 95% if all four markers measured (CA27...
August 23, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28841919/mesonephric-adenocarcinoma-of-the-uterine-corpus-with-intracystic-growth-completely-confined-to-the-myometrium-a-case-report-and-literature-review
#18
Hiroka Ando, Yuko Watanabe, Minori Ogawa, Hiromi Tamura, Tomomi Deguchi, Kayo Ikeda, Mayumi Fujitani, Mitsunori Shioji, Tomoko Tsujie, Reiko Doi, Akinori Wakimoto, Shiro Adachi
BACKGROUND: Mesonephric adenocarcinoma (MA) is a rare tumor believed to arise from mesonephric remnants occurring mostly in the uterine cervix and, to a lesser extent, the corpus. Since the first case report of MA in the corpus in 1995, only 16 cases have been reported in the English literature. A recent report suggested that MA originates in Müllerian tissue and exhibits the mesonephric differentiation phenotype. CASE PRESENTATION: An asymptomatic 61-year-old woman was referred to our hospital because of elevated levels of tumor markers...
August 25, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28840443/preoperative-carbohydrate-antigen-19-9-its-neglected-role-in-alpha-fetoprotein-negative-hepatocellular-carcinoma-patients
#19
Liang-He Lu, Yong-Fa Zhang, Wei Wei, Ming Shi, Rong-Ping Guo
PURPOSE: The study aimed to investigate the prognostic role of the preoperative carbohydrate antigen 19-9 (CA19-9) level in alpha-fetoprotein (AFP)-negative (AFP < 25 ng/ml) hepatocellular carcinoma (HCC) patients. METHODS: From December 2004 to December 2013, 750 patients diagnosed with AFP-negative HCC following curative resection were enrolled. Both univariate and multivariate analyses were performed to clarify the prognostic factors for overall survival (OS) and disease-free survival (DFS)...
August 24, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28836521/a-prospective-study-of-endoscopic-ultrasonography-features-cyst-fluid-carcinoembryonic-antigen-and-fluid-cytology-for-the-differentiation-of-small-pancreatic-cystic-neoplasms
#20
Ying Wang, Ningli Chai, Jia Feng, Enqiang Linghu
BACKGROUND AND OBJECTIVES: With improvements in imaging technologies, pancreatic cystic lesions (PCLs) have been increasingly identified in recent years. However, the imaging modalities used to differentiate the categories of pancreatic cysts remain limited, which may cause confusion when planning treatment. Due to progress in endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) technology, auxiliary diagnosis by the detection of cystic fluid has become a recent trend. METHODS: From March 2015 to April 2016, 120 patients with PCLs were enrolled in this study...
August 24, 2017: Endoscopic Ultrasound
keyword
keyword
51142
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"