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https://www.readbyqxmd.com/read/28808651/evaluation-of-acute-aortic-dissection-type-a-factors-and-comparison-the-postoperative-clinical-outcomes-between-two-surgical-methods
#1
Hasan Shemirani, Amir Mirmohamadsadeghi, Behzad Mahaki, Sadaf Farhadi, Reza Mohseni Badalabadi, Peyman Bidram, Mehdi Mohseni Badalabadi
BACKGROUND: Although aortic dissection is a rare disease, it causes high level of mortality. If ascending aorta gets involved in this disease, it is known as type A. According to small number of studies about this disease in Iran, this study conducted to detect the factors related to acute aortic dissection type A, its surgery consequences and the factors affecting them. MATERIALS AND METHODS: In this historical cohort study, all patients having acute aortic dissection type A referring to Chamran Hospital from 2006 to 2012 were studied...
2017: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28807406/longitudinal-changes-in-segmental-aortic-stiffness-determined-by-cardiac-magnetic-resonance-in-children-and-young-adults-with-connective-tissue-disorders-the-marfan-loeys-dietz-and-ehlers-danlos-syndromes-and-nonspecific-connective-tissue-disorders
#2
Anthony Merlocco, Ronald V Lacro, Kimberlee Gauvreau, Nicole Rabideau, Michael N Singh, Ashwin Prakash
Aortic stiffness measured by cardiac magnetic resonance (CMR) in connective tissue disorder (CTD) patients has been previously shown to be abnormal and to be associated with adverse aortic outcomes. The rate of increase in aortic stiffness with normal aging has been previously described. However, longitudinal changes in aortic stiffness have not been characterized in CTD patients. We examined longitudinal changes in CMR-derived aortic stiffness in children and young adults with CTDs. A retrospective analysis of 50 children and young adults (median age, 20 years; range, 0...
July 14, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28805011/bicuspid-and-unicuspid-aortic-valves-different-phenotypes-of-the-same-disease-insight-from-the-gentac-registry
#3
Joseph M Krepp, Mary J Roman, Richard B Devereux, Adrienne Bruce, Siddharth K Prakash, Shaine A Morris, Dianna M Milewicz, Kathryn W Holmes, William Ravekes, Ralph V Shohet, Reed E Pyeritz, Cheryl L Maslen, Barbara L Kroner, Kim A Eagle, Liliana Preiss, Federico M Asch
BACKGROUND: Unicuspid aortic valve (UAV) is a rare disorder, often difficult to distinguish from bicuspid aortic valve (BAV). BAV and UAV share valve pathology such as the presence of a raphe, leaflet fusion, aortic stenosis, aortic regurgitation, and/or ascending aortic dilatation, but a comprehensive echocardiographic comparison of patients with UAV and BAV has not been previously performed. METHODS: We investigated UAV and BAV patients at an early stage of disease included in GenTAC, a national registry of genetically related aortic aneurysms and associated cardiac conditions...
August 14, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28804238/percutaneous-closure-of-the-aorto-ostial-origin-of-a-coronary-artery-saphenous-bypass-graft-with-a-large-pseudoaneurysm-using-the-amplatzer-muscular-ventricular-septal-defect-occluder
#4
Nicolas W Shammas, Majid Z Chammas, Jon Robken, Dale Geiss
We report the case of a 76-year-old male patient with a history of coronary artery bypass graft surgery presented with a large pseudoaneurysm emerging from a previously occluded saphenous bypass graft (SVG). A largely contained hematoma is seen in the mediastinum on computed tomography angiography (CTA) of the chest. Flow was seen from the ascending aorta into the pseudoaneurysm through the aorto-ostial opening of the bypass graft. Closure of the aorto-ostial origin of the graft was performed using the AMPLATZER muscular ventricular septal defect (VSD) occluder (St Jude's Medical, St...
September 2017: International Journal of Angiology: Official Publication of the International College of Angiology, Inc
https://www.readbyqxmd.com/read/28801038/qrs-duration-reflects-underlying-changes-in-conduction-velocity-during-increased-intraventricular-pressure-and-heart-failure
#5
REVIEW
Jorge G Quintanilla, Javier Moreno, Tamara Archondo, José Manuel Alfonso-Almazán, José María Lillo-Castellano, Elena Usandizaga, María Jesús García-Torrent, Cruz Rodríguez-Bobada, Pablo González, Luis Borrego, Victoria Cañadas-Godoy, Juan J González-Ferrer, Nicasio Pérez-Castellano, Julián Pérez-Villacastín, David Filgueiras-Rama
Pressure overload and heart failure electrophysiological remodeling (HF-ER) in pigs are associated with decreased conduction velocity (CV) and dispersion of repolarization, which lead to higher risk of ventricular arrhythmia. This work aimed to establish the correlation between QRS complex duration and underlying changes in CV during increased intraventricular pressure (IVP) and/or HF-ER ex-vivo, and to determine whether QRS duration could be sensitive to an acute increase in left ventricular afterload in-vivo...
August 8, 2017: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/28799113/angles-between-the-aortic-root-and-the-left-ventricle-assessed-by-mdct-are-associated-with-the-risk-of-aortic-regurgitation-after-transcatheter-aortic-valve-replacement
#6
Vincent Roule, Alexandre Placente, Rémi Sabatier, Mathieu Bignon, Vladimir Saplacan, Calin Ivascau, Paul Milliez, Farzin Beygui
OBJECTIVES: To evaluate the impact of the angles quantified by multidetector computed tomography (MDCT) between the ascending aorta's long axis and, the left ventricular inflow long axis (LVLA), or the left ventricule outflow tract long axis, and the occurrence of post-transcatheter aortic valve replacement (TAVR) aortic regurgitation (AR). METHODS: We prospectively included 136 consecutive patients who underwent a transfemoral TAVR with a preoperative MDCT. The groups were defined according to AR <2 or ≥2 assessed by echocardiography at 1 month...
August 10, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/28795032/extra-anatomic-ascending-aorta-to-abdominal-aorta-bypass-in-takayasu-arteritis-patients-with-mid-aortic-syndrome
#7
Hak Ju Kim, Jae-Woong Choi, Ho Young Hwang, Hyuk Ahn
BACKGROUND: We evaluated the operative outcomes of an extra-anatomic bypass from the ascending aorta to the abdominal aorta in patients with type II or III Takayasu arteritis (TA) with mid-aortic syndrome. METHODS: From 1988 to 2014, 8 patients with type II (n=2) or III (n=6) TA underwent an ascending aorta to abdominal aorta bypass. The mean patient age was 43.5±12.2 years and the mean peak pressure gradient between the upper and lower extremities was 54.8±39...
August 2017: Korean Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28793046/influence-of-the-tilt-angle-of-percutaneous-aortic-prosthesis-on-velocity-and-shear-stress-fields
#8
Bruno Alvares de Azevedo Gomes, Gabriel Cordeiro Camargo, Jorge Roberto Lopes Dos Santos, Luis Fernando Alzuguir Azevedo, Ângela Ourivio Nieckele, Aristarco Gonçalves Siqueira-Filho, Glaucia Maria Moraes de Oliveira
Background: Due to the nature of the percutaneous prosthesis deployment process, a variation in its final position is expected. Prosthetic valve placement will define the spatial location of its effective orifice in relation to the aortic annulus. The blood flow pattern in the ascending aorta is related to the aortic remodeling process, and depends on the spatial location of the effective orifice. The hemodynamic effect of small variations in the angle of inclination of the effective orifice has not been studied in detail...
August 7, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28790243/-valve-replacement-for-severe-aortic-stenosis-in-a-patient-with-tangier-disease
#9
Atsushi Tamura, Takamichi Yoshizaki, Sho Kusadokoro
We report a case of severe aortic valve stenosis in a patient with Tangier disease. A 64-year-old female was diagnosed with Tangier disease on the basis of gene mutation. The serum levels of total cholesterol and high-density lipoprotein were 124 mg/dl and 4.3 mg/dl, respectively. She had a symptom of dyspnea and echocardiography revealed severe aortic valve stenosis with the maximum gradient of 60.5 mmHg. Chest computed tomography showed severe calcification of the ascending aorta and the aortic root. Aortic valve replacement using a bioprosthetic valve was performed...
August 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28782645/marfan-syndrome-a-connective-tissue-disease-at-the-crossroads-of-mechanotransduction-tgf%C3%AE-signaling-and-cell-stemness
#10
REVIEW
Francesco Ramirez, Cristina Caescu, Elisabeth Wondimu, Josephine Galatioto
Mutations in fibrillin-1 cause Marfan syndrome (MFS), the most common heritable disorder of connective tissue. Fibrillin-1 assemblies (microfibrils and elastic fibers) represent a unique dual-function component of the architectural matrix. The first role is structural for they endow tissues with tensile strength and elasticity, transmit forces across them and demarcate functionally discrete areas within them. The second role is instructive in that these macroaggregates modulate a large variety of sub-cellular processes by interacting with mechanosensors, and integrin and syndecan receptors, and by modulating the bioavailability of local TGFβ signals...
August 4, 2017: Matrix Biology: Journal of the International Society for Matrix Biology
https://www.readbyqxmd.com/read/28782135/ultrasound-evaluation-of-left-ventricular-and-aortic-fibrosis-after-pre-eclampsia
#11
Rossana Orabona, Edoardo Sciatti, Enrico Vizzardi, Ivano Bonadei, Federico Prefumo, Adriana Valcamonico, Marco Metra, Tiziana Frusca
OBJECTIVES: Myocardial fibrosis is linked with adverse clinical outcomes in adults. The objective was to investigate the presence of myocardial and/or aortic fibrosis in asymptomatic women with a history of early-onset (EO) or late-onset (LO) pre-eclampsia (PE) by echocardiographic calibrated integrated backscatter (cIBS). METHODS: 30 women who experienced pregnancies complicated by EOPE, 30 with a previous LOPE and 30 controls were retrospectively selected from our electronic database and then recalled from 6 months to 4 years after delivery...
August 7, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28773988/investigation-on-the-regional-loss-factor-and-its-anisotropy-for-aortic-aneurysms
#12
Nastaran Shahmansouri, Mohammed Alreshidan, Alexander Emmott, Kevin Lachapelle, Ismaïl El-Hamamsy, Raymond Cartier, Richard L Leask, Rosaire Mongrain
An aortic aneurysm is a lethal arterial disease that mainly occurs in the thoracic and abdominal regions of the aorta. Thoracic aortic aneurysms are prevalent in the root/ascending parts of the aorta and can lead to aortic rupture resulting in the sudden death of patients. Understanding the biomechanical and histopathological changes associated with ascending thoracic aortic aneurysms (ATAAs), this study investigates the mechanical properties of the aorta during strip-biaxial tensile cycles. The loss factor-defined as the ratio of dissipated energy to the energy absorbed during a tensile cycle-the incremental modulus, and their anisotropy indexes were compared with the media fiber compositions for aneurysmal (n = 26) and control (n = 4) human ascending aortas...
October 26, 2016: Materials
https://www.readbyqxmd.com/read/28767581/diagnostic-value-of-pet-ct-for-giant-cell-arteritis-combined-with-pulmonary-embolism-presenting-case-report-and-literature-review
#13
Xiaoming Shu, Xiaoxiang Xu, Qinglin Peng, Xin Lu, Li Ma, Na Mi, Guochun Wang
RATIONALE: Giant cell arteritis (GCA) combined with concomitant pulmonary embolism (PE) is extremely difficult to diagnose because of its low incidence and atypical clinical presentations. PATIENT CONCERNS: A 62-year-old male developed fever of unknown origin. DIAGNOSES: Positron emission tomography/computed tomography (PET/CT) revealed increased glucose metabolism in the vascular walls of the ascending and descending aorta and pulmonary artery, leading to a diagnosis of GCA combined with PE...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28765763/elongated-ascending-aorta-predicts-a-short-distance-between-his-bundle-potential-recording-site-and-coronary-sinus-ostium
#14
Yuichi Momose, Kyoko Soejima, Akiko Ueda, Takahiro Arai, Masamichi Koyanagi, Yo Hagiwara, Ikuko Togashi, Yosuke Miwa, Kyoko Hoshida, Mutsumi Miyakoshi, Noriko Matsushita, Mika Nagaoka, Toshiaki Sato, Toshiaki Nitatori, Hideaki Yoshino
BACKGROUND: When performing catheter ablation of atrioventricular nodal reentrant tachycardia (AVNRT), it can be difficult to maintain a safe distance from the His recording site to avoid AV block in patients with a short distance between this recording site to the coronary sinus (CS) ostium (small triangle of Koch [TOK]). In this study, we sought to identify parameters predicting small TOK and test these parameters in patients undergoing AVNRT catheter ablation. METHODS: Twenty-eight patients who underwent catheter ablation of atrial fibrillation using a three-dimensional (3D) electroanatomical mapping system (EAM) with computed tomography (CT) merge (23 males; mean age, 65...
August 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28765187/non-atherosclerotic-aortic-mural-thrombus-a-rare-source-of-embolism
#15
Julian A Marin-Acevedo, Andree H Koop, Jose L Diaz-Gomez, Pramod K Guru
A 54-year-old man presented to the emergency department with acute left-sided chest pain and left upper quadrant abdominal pain. He had a significant history of squamous cell carcinoma of the lung previously treated with right pneumonectomy who ; is currently receiving adjuvant chemotherapy with cisplatin. Physical examination was remarkable for tachycardia, hypertension and mild abdominal tenderness. CT angiography revealed an aortic mural thrombus in the ascending aorta and aortic arch without dissection, aneurysm or tortuosity of the aorta...
August 1, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28762641/mri-measurements-of-the-thoracic-aorta-and-pulmonary-artery
#16
Leyla Beck, Abdi-Aziz Mohamed, Wendy E Strugnell, Harry Bartlett, Viviana Rodriguez, Christian Hamilton-Craig, Richard E Slaughter
INTRODUCTION: The purpose of this study was to obtain a range of normal measurements of the adult thoracic aorta and main pulmonary artery using cardiac MRI, and to assess agreement between measurements made on ECG-gated two-dimensional (2D) breath held steady-state-free precession (SSFP), and three-dimensional (3D) breath held SSFP image acquisitions. METHODS: Forty-nine normal volunteers underwent cardiac MRI using a 1.5T system. Two independent examiners measured the ascending aorta, aortic arch, descending thoracic aorta and main pulmonary artery in pre-defined locations...
August 1, 2017: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/28762441/severe-aortic-regurgitation-complicating-takayasu-s-arteritis
#17
Wala M Alali, Saeed A Alahmari, Yahya S Alhebaishi, Seham A Alrashidi
We present an uncommon case of a 48-year-old female patient with symptomatic presentation of a severe aortic regurgitation with aneurysm of the ascending aorta and progressive dyspnea. Detailed investigation of laboratory tests and imaging identified Takayasu's arteritis (TA) as the underlying etiology. Computed tomography scan revealed complete occlusion of the right carotid artery as well as stenosis at the origins of left subclavian and vertebral arteries. In addition, cardiac magnetic resonance angiogram showed aneurysm at the proximal segment of right subclavian artery...
August 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28761401/modified-port-access-technique-for-the-treatment-of-aortic-dissection-after-previous-cardiac-surgery
#18
Edvin Prifti, Aurel Demiraj, Roland Xhaxho
One of the most challenging conditions to manage after previous cardiac surgery is chronic dissection of the ascending aorta. We operated on a 54-year-old man who had aortic dissection in addition to large aortic dimensions very close to the sternum, severe aortic regurgitation, and a false lumen in the descending aorta. We used a combination of perfusion and myocardial protection techniques, arising from port-access technology, that enabled antegrade flow into the aorta, endoclamping of the ascending aorta, the administration of cardioplegic solution before opening the sternum, and left ventricular venting to prevent ventricular distention...
June 2017: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/28758558/acute-debakey-type-i-dissection-repair-using-frozen-elephant-trunk-the-cleveland-clinic-technique
#19
Muhammad Aftab, Ryan Plichta, Eric E Roselli
Over the past 3 decades, the standard surgical management for acute DeBakey type I aortic dissection has not significantly changed. Most patients undergo ascending aortic replacement with an interposition graft under hypothermic circulatory arrest with selective root replacement. Nevertheless, with the improvement in overall patient care, acute surgical outcomes continue to improve. The frozen elephant trunk (FET) technique was introduced as a modification to conventional elephant trunk to treat extensive degenerative and chronic dissecting aneurysms involving the aortic arch and the proximal descending aorta...
September 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28753691/experimental-study-of-anisotropic-stress-strain-relationships-of-aortic-and-pulmonary-artery-homografts-and-synthetic-vascular-grafts
#20
Yueqian Jia, Yangyang Qiao, I Ricardo Argueta-Morales, Aung Maung, Jack Norfleet, Yuanli Bai, Eduardo Divo, Alain J Kassab, William M DeCampli
Homografts and synthetic grafts are used in surgery for congenital heart disease (CHD). Determining these materials' mechanical properties will aid in understanding tissue behavior when subjected to abnormal CHD hemodynamics. Homograft tissue samples from anterior/posterior aspects, of ascending/descending aorta (AA, DA), innominate artery (IA), left subclavian artery (LScA), left common carotid artery (LCCA), main/left/right pulmonary artery (MPA, LPA, RPA), and synthetic vascular grafts, were obtained in three orientations: circumferential, diagonal (45 deg relative to circumferential direction), and longitudinal...
October 1, 2017: Journal of Biomechanical Engineering
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