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https://www.readbyqxmd.com/read/28339966/operational-challenges-and-opportunities-in-pastured-poultry-operations-in-the-united-states
#1
C Elkhoraibi, M Pitesky, N Dailey, D Niemeier
As pastured poultry production has gained increased popularity in the United States in recent years, there is a growing need for research and outreach efforts aimed at this sector of poultry production. In order to get familiarized with American pastured poultry producers, we conducted an online questionnaire aimed primarily at evaluating what operational challenges are faced by producers and what educational opportunities should be initiated by researchers. Results showed that pastured poultry farms largely vary in total number of acres farmed and total number of birds kept...
March 3, 2017: Poultry Science
https://www.readbyqxmd.com/read/28339685/information-needs-of-generalists-and-specialists-using-online-best-practice-algorithms-to-answer-clinical-questions
#2
David A Cook, Kristi J Sorensen, Jane A Linderbaum, Laurie J Pencille, Deborah J Rhodes
Objective: : To better understand clinician information needs and learning opportunities by exploring the use of best-practice algorithms across different training levels and specialties. Methods: : We developed interactive online algorithms (care process models [CPMs]) that integrate current guidelines, recent evidence, and local expertise to represent cross-disciplinary best practices for managing clinical problems. We reviewed CPM usage logs from January 2014 to June 2015 and compared usage across specialty and provider type...
February 19, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28334224/computational-modeling-of-in-vivo-and-in-vitro-protein-dna-interactions-by-multiple-instance-learning
#3
Zhen Gao, Jianhua Ruan
Motivation: The study of transcriptional regulation is still difficult yet fundamental in molecular biology research. While the development of both in vivo and in vitro profiling techniques have significantly enhanced our knowledge of transcription factor (TF)-DNA interactions, computational models of TF-DNA interactions are relatively simple and may not reveal sufficient biological insight. In particular, supervised learning based models for TF-DNA interactions attempt to map sequence-level features ( k -mers) to binding event but usually ignore the location of k -mers, which can cause data fragmentation and consequently inferior model performance...
March 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28334114/biren-predicting-enhancers-with-a-deep-learning-based-model-using-the-dna-sequence-alone
#4
Bite Yang, Feng Liu, Chao Ren, Zhangyi Ouyang, Ziwei Xie, Xiaochen Bo, Wenjie Shu
Motivation: Enhancer elements are noncoding stretches of DNA that play key roles in controlling gene expression programmes. Despite major efforts to develop accurate enhancer prediction methods, identifying enhancer sequences continues to be a challenge in the annotation of mammalian genomes. One of the major issues is the lack of large, sufficiently comprehensive and experimentally validated enhancers for humans or other species. Thus, the development of computational methods based on limited experimentally validated enhancers and deciphering the transcriptional regulatory code encoded in the enhancer sequences is urgent...
February 17, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28334023/preferences-for-the-provision-of-whole-genome-sequencing-services-among-young-adults
#5
Christopher H Wade, Kailyn R Elliott
OBJECTIVES: As whole genome sequencing (WGS) becomes increasingly available, clinicians will be faced with conveying complex information to individuals at different stages in life. The purpose of this study is to characterize the views of young adults toward obtaining WGS, learning different types of genomic information, and having choice about which results are disclosed. METHODS: A mixed-methods descriptive study was conducted with a diverse group of 18 and 19-years-olds (N = 145)...
2017: PloS One
https://www.readbyqxmd.com/read/28333620/binary-online-learned-descriptors
#6
Vassileios Balntas, Lilian Tang, Krystian Mikolajczyk
We propose a novel approach to generate a binary descriptor optimized for each image patch independently. The approach is inspired by the linear discriminant embedding that simultaneously increases inter and decreases intra class distances. A set of discriminative and uncorrelated binary tests is established from all possible tests in an offline training process. The patch adapted descriptors are then efficiently built online from a subset of features which lead to lower intra-class distances and thus, to a more robust descriptor...
March 20, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28331219/intragenic-multi-exon-deletion-in-the-fbn1-gene-in-a-child-with-mildly-dilated-aortic-sinus-a-retrotransposal-event
#7
Maggie Brett, George Korovesis, Angeline H M Lai, Eileen C P Lim, Ene-Choo Tan
Marfan syndrome is an autosomal dominant disorder affecting mainly the skeletal, ocular and cardiovascular systems. Most cases are caused by mutations in the fibrillin-1 gene (FBN1), although there are some reports on deletions involving FBN1 and other additional genes. We report a male patient who was first evaluated at 4 years of age. Echocardiogram showed a mildly dilated aortic sinus. He also had a history of muscular ventral septal defect which was closed spontaneously and trivial mitral regurgitation...
March 23, 2017: Journal of Human Genetics
https://www.readbyqxmd.com/read/28330403/communicating-with-residents-about-risks-following-the-fukushima-nuclear-accident
#8
Michio Murakami, Akiko Sato, Shiro Matsui, Aya Goto, Atsushi Kumagai, Masaharu Tsubokura, Makiko Orita, Noboru Takamura, Yujiro Kuroda, Sae Ochi
The Fukushima nuclear accident in March 2011 posed major threats to public health. In response, medical professionals have tried to communicate the risks to residents. To investigate forms of risk communication and to share lessons learned, we reviewed medical professionals' activities in Fukushima Prefecture from the prefectural level to the individual level: public communication through Fukushima Health Management Surveys, a Yorozu ("general") health consultation project, communications of radiological conditions and health promotion in Iitate and Kawauchi villages, dialogues based on whole-body counter, and science communications through online media...
March 2017: Asia-Pacific Journal of Public Health
https://www.readbyqxmd.com/read/28329840/a-multi-faceted-approach-to-promote-comprehension-of-online-health-information-among-older-adults
#9
Jessie Chin, Darcie D Moeller, Jessica Johnson, Elise A G Duwe, James F Graumlich, Michael D Murray, Daniel G Morrow
Purpose of the Study: Older adults' self-care often depends on understanding and utilizing health information. Inadequate health literacy among older adults poses a barrier to self-care because it hampers comprehension of this information, particularly when the information is not well-designed. Our goal was to improve comprehension of online health information among older adults with hypertension who varied in health literacy abilities. Design and Methods: We identified passages about hypertension self-care from credible websites (typical passages)...
March 10, 2017: Gerontologist
https://www.readbyqxmd.com/read/28328305/development-and-implementation-of-online-training-modules-on-abuse-neglect-and-exploitation
#10
Farida K Ejaz, Miriam Rose, Georgia Anetzberger
Online training for care managers to identify, report, and prevent abuse, neglect, and exploitation was developed for a demonstration involving the dually eligible Medicare and Medicaid population. It was comprised of three modules covering background, screening, and reporting abuse. Of 453 enrollees, 273 completed at least one module and 212 completed all three. Pre- and post-training surveys for each module were used to examine changes in the proportion of correct answers for each question, using the related-samples Cochran's Q statistic...
March 22, 2017: Journal of Elder Abuse & Neglect
https://www.readbyqxmd.com/read/28328169/student-nurses-competence-in-sexual-health-care-a-literature-review
#11
REVIEW
Emma Pascale Blakey, Helen Aveyard
AIM: The aim of this literature review is to explore the way in which sexual health care is perceived and experienced by students in clinical practice. BACKGROUND: Student nurses understand the need to learn about sexual health but report a variety of learning needs and experience challenges acquiring skills to deliver such care in part due to varied clinical experience. Furthermore, there is a paucity of data exploring clinical competence of sexual health care among student nurses...
March 22, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28327575/analysis-of-exome-data-for-4293-trios-suggests-gpi-anchor-biogenesis-defects-are-a-rare-cause-of-developmental-disorders
#12
Alistair T Pagnamenta, Yoshiko Murakami, John M Taylor, Consuelo Anzilotti, Malcolm F Howard, Venessa Miller, Diana S Johnson, Shereen Tadros, Sahar Mansour, I Karen Temple, Rachel Firth, Elisabeth Rosser, Rachel E Harrison, Bronwen Kerr, Niko Popitsch, Taroh Kinoshita, Jenny C Taylor, Usha Kini
Over 150 different proteins attach to the plasma membrane using glycosylphosphatidylinositol (GPI) anchors. Mutations in 18 genes that encode components of GPI-anchor biogenesis result in a phenotypic spectrum that includes learning disability, epilepsy, microcephaly, congenital malformations and mild dysmorphic features. To determine the incidence of GPI-anchor defects, we analysed the exome data from 4293 parent-child trios recruited to the Deciphering Developmental Disorders (DDD) study. All probands recruited had a neurodevelopmental disorder...
March 22, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28327572/the-role-of-genetic-counsellors-in-genomic-healthcare-in-the-united-kingdom-a-statement-by-the-association-of-genetic-nurses-and-counsellors
#13
Anna Middleton, Peter Marks, Anita Bruce, Liwsi K Protheroe-Davies, Cath King, Oonagh Claber, Catherine Houghton, Claire Giffney, Rhona Macleod, Claire Dolling, Sue Kenwrick, Diana Scotcher, Georgina Hall, Christine Patch, Laura Boyes
In the United Kingdom, genetic counsellors work together with clinical geneticists and clinical scientist colleagues within specialist genetics services, but they also often work in multidisciplinary teams (MDTs) outside of such services. There, they contribute genetic knowledge together with expert understanding of how to communicate genetic information effectively. They can offer education and support to the MDT, while providing management advice for both affected patients and the extended at-risk family members...
March 22, 2017: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/28324696/online-neural-monitoring-of-statistical-learning
#14
Laura J Batterink, Ken A Paller
The extraction of patterns in the environment plays a critical role in many types of human learning, from motor skills to language acquisition. This process is known as statistical learning. Here we propose that statistical learning has two dissociable components: (1) perceptual binding of individual stimulus units into integrated composites and (2) storing those integrated representations for later use. Statistical learning is typically assessed using post-learning tasks, such that the two components are conflated...
February 24, 2017: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28322276/identifying-fast-onset-antidepressants-using-rodent-models
#15
M J Ramaker, S C Dulawa
Depression is a leading cause of disability worldwide and a major contributor to the burden of suicide. A major limitation of classical antidepressants is that 2-4 weeks of continuous treatment is required to elicit therapeutic effects, prolonging the period of depression, disability and suicide risk. Therefore, the development of fast-onset antidepressants is crucial. Preclinical identification of fast-onset antidepressants requires animal models that can accurately predict the delay to therapeutic onset. Although several well-validated assay models exist that predict antidepressant potential, few thoroughly tested animal models exist that can detect therapeutic onset...
March 21, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28321248/patch-based-multiple-instance-learning-algorithm-for-object-tracking
#16
Zhenjie Wang, Lijia Wang, Hua Zhang
To deal with the problems of illumination changes or pose variations and serious partial occlusion, patch based multiple instance learning (P-MIL) algorithm is proposed. The algorithm divides an object into many blocks. Then, the online MIL algorithm is applied on each block for obtaining strong classifier. The algorithm takes account of both the average classification score and classification scores of all the blocks for detecting the object. In particular, compared with the whole object based MIL algorithm, the P-MIL algorithm detects the object according to the unoccluded patches when partial occlusion occurs...
2017: Computational Intelligence and Neuroscience
https://www.readbyqxmd.com/read/28321132/the-outcomes-of-health-promoting-communities-being-active-eating-well-initiative-a-community-based-obesity-prevention-intervention-in-victoria-australia
#17
K A Bolton, P Kremer, L Gibbs, E Waters, B Swinburn, A de Silva
OBJECTIVE: To evaluate the impact of the Health Promoting Communities: Being Active Eating Well (HPC:BAEW, 2007-2010) initiative which comprised of community-based multi-component interventions adapted to community context in five separate communities. The intervention aimed to promote healthy eating, physical activity and stronger, healthier communities. METHODS: A mixed method and multi-level quasi-experimental evaluation of the HPC:BAEW initiative captured process, impact and outcome data...
March 21, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28320651/collaborative-active-visual-recognition-from-crowds-a-distributed-ensemble-approach
#18
Gang Hua, Chengjiang Long, Ming Yang, Yan Gao
Active learning is an effective way of engaging users to interactively train models for visual recognition more efficiently. The vast majority of previous works focused on active learning with a single human oracle. The problem of active learning with multiple oracles in a collaborative setting has not been well explored. We present a collaborative computational model for active learning with multiple human oracles, the input from whom may be subject to different levels of noise. It leads to not only an ensemble kernel machine that is robust to label noise, but also a principled label quality measure to online detect irresponsible labelers...
March 15, 2017: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/28318904/dual-memory-neural-networks-for-modeling-cognitive-activities-of-humans-via-wearable-sensors
#19
Sang-Woo Lee, Chung-Yeon Lee, Dong-Hyun Kwak, Jung-Woo Ha, Jeonghee Kim, Byoung-Tak Zhang
Wearable devices, such as smart glasses and watches, allow for continuous recording of everyday life in a real world over an extended period of time or lifelong. This possibility helps better understand the cognitive behavior of humans in real life as well as build human-aware intelligent agents for practical purposes. However, modeling the human cognitive activity from wearable-sensor data stream is challenging because learning new information often results in loss of previously acquired information, causing a problem known as catastrophic forgetting...
February 20, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/28318439/focused-assessment-with-sonography-in-trauma-fast-in-2017-what-radiologists-can-learn
#20
John R Richards, John P McGahan
Focused assessment with sonography in trauma (FAST) has been extensively utilized and studied in blunt and penetrating trauma for the past 3 decades. Prior to FAST, invasive procedures such as diagnostic peritoneal lavage and exploratory laparotomy were commonly utilized to diagnose intraabdominal injury. Today the FAST examination has evolved into a more comprehensive study of the abdomen, heart, chest, and inferior vena cava, and many variations in technique, protocols, and interpretation exist. Trauma management strategies such as laparotomy, laparoscopy, endoscopy, computed tomographic angiography, angiographic intervention, serial imaging, and clinical observation have also changed over the years...
April 2017: Radiology
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