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https://www.readbyqxmd.com/read/28646260/salt-appetite-and-the-influence-of-opioids
#1
Craig M Smith, Andrew J Lawrence
Due to the biological importance of sodium and its relative scarcity within many natural environments, 'salt appetite' has evolved whereby dietary salt is highly sought after and palatable when tasted. In addition to peripheral responses, salt depletion is detected within the brain via circumventricular organs and 11β-hydroxysteroid dehydrogenase type 2 (HSD2) neurons to increase salt appetite. Salt appetite is comprised of two main components. One component is the incentive salience or motivation for salt (i...
June 24, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/28644412/a-systematic-review-of-fatalities-related-to-acute-ingestion-of-salt-a-need-for-warning-labels
#2
REVIEW
Norm R C Campbell, Emma J Train
There are sporadic cases of fatalities from acutely eating salt. Yet, on social media, there are "challenges to" and examples of children and some adults acutely eating salt, and recently a charity advocated eating small amounts of salt to empathize with Syrian refugees. We performed a systematic review of fatalities from ingesting salt to assess if relatively moderate doses of salt could be fatal. In 27 reports, there were 35 fatalities documented (19 in adults and 16 in children). The lethal dose was estimated to be less than 10 g of sodium (<5 teaspoons of salt) in two children, and less than 25 g sodium in four adults (<4 tablespoons of salt)...
June 23, 2017: Nutrients
https://www.readbyqxmd.com/read/28637899/dietary-salt-exacerbates-experimental-colitis
#3
Alan L Tubbs, Bo Liu, Troy D Rogers, R Balfour Sartor, Edward A Miao
The Western diet is characterized by high protein, sugar, fat, and low fiber intake, and is widely believed to contribute to the incidence and pathogenesis of inflammatory bowel disease (IBD). However, high sodium chloride salt content, a defining feature of processed foods, has not been considered as a possible environmental factor that might drive IBD. We set out to bridge this gap. We examined murine models of colitis on either a high salt diet (HSD) or a low salt diet. We demonstrate that an HSD exacerbates inflammatory pathology in the IL-10-deficient murine model of colitis relative to mice fed a low salt diet...
June 21, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28635325/effect-of-salt-loading-on-baroreflex-sensitivity-in-reduced-renal-mass-hypertension
#4
Besim Özaykan, Eylem Taskin, Ali Magemizoğlu
BACKGROUND: High dietary salt, as well as renal mass reduction, is known to decrease baroreflex sensitivity in rats. However, the effect of high salt intake on baroreflex sensitivity is unknown in reduced renal mass (RRM) hypertension; therefore, the aim of this study was to investigate the effects of salt loading on arterial baroreflex sensitivity and mean arterial pressure (MAP) in RRM hypertension. METHODS: Both RRM and sham-operated control (SO) rats were loaded with 0...
June 21, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28624518/role-of-gut-microbiota-against-calcium-oxalate
#5
REVIEW
Humaira Sadaf, Syed Irfan Raza, Syed Waqas Hassan
Nephrolithiasis is a condition marked by the presence or formation of stones in kidneys. Several factors contribute to kidney stones development such as environmental conditions, type of dietary intake, gender and gastrointestinal flora. Most of the kidney stones are composed of calcium phosphate and calcium oxalate, which enter in to the body through diet. Both sources of oxalates become dangerous when normal flora of gastrointestinal tract is disturbed. Oxalobacter and Lactobacillus species exist symbiotically in the human gut and prevent stone formation by altering some biochemical pathways through production of specific enzymes which help in the degradation of oxalate salts...
June 15, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28623056/the-prevalence-and-risk-factor-control-associated-with-noncommunicable-diseases-in-china-japan-and-korea
#6
Defu Ma, Hiromichi Sakai, Chihiro Wakabayashi, Jong-Sook Kwon, Yoonna Lee, Shuo Liu, Qiaoqin Wan, Kumiko Sasao, Kanade Ito, Ken Nishihara, Peiyu Wang
BACKGROUND: Noncommunicable disease (NCD) has become the leading cause of mortality and disease burden worldwide. METHODS: A cross-sectional survey was carried out to investigate the prevalence of NCDs and risk factor control on dietary behaviors and dietary intake in China, Japan, and Korea. RESULTS: There were significant differences among the three countries on the prevalence of hypertension (24.5% in China, 17.6% in Korea, and 15.2% in Japan), diabetes (8...
June 13, 2017: Journal of Epidemiology
https://www.readbyqxmd.com/read/28622779/-iron-in-nutrition
#7
P Tounian, J-P Chouraqui
Iron deficiency is the main nutritional disease worldwide. The multidisciplinary working group of the French Pediatric Society on iron assessed the following recommendations. Since iron is variably absorbed depending on foods, the group defined absorbed iron requirements instead of dietary iron requirements. Iron-rich foods should be introduced at 4-months of age in some breast-fed infants. Between 7 and 11 month-old, formula-fed infants should drink at least 700ml per day of follow-on formula and partially or totally breast-fed infants should receive oral iron supplementation...
May 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28621720/know-your-noodles-assessing-variations-in-sodium-content-of-instant-noodles-across-countries
#8
Clare Farrand, Karen Charlton, Michelle Crino, Joseph Santos, Rodrigo Rodriguez-Fernandez, Cliona Ni Mhurchu, Jacqui Webster
Reducing salt intake is a cost-effective public health intervention to reduce the global burden of non-communicable disease (NCDs). Ultra-processed foods contribute ~80% of dietary salt in high income countries, and are becoming prominent in low-middle income countries. Instant noodle consumption is particularly high in the Asia Pacific region. The aim of this study was to compare the sodium content of instant noodles sold worldwide to identify potential for reformulation. Analysis was undertaken for 765 instant noodle products from 10 countries using packaged food composition databases of ultra-processed foods compiled by the Global Food Monitoring Group (GFMG) and national shop survey data...
June 16, 2017: Nutrients
https://www.readbyqxmd.com/read/28617545/fluid-status-of-patients-during-the-early-stages-of-continuous-ambulatory-peritoneal-dialysis
#9
L Wang, W Yu, T Wang
OBJECTIVE: The purpose of this paper is to investigate the fluid status of patients in the early stages of continuous ambulatory peritoneal dialysis (CAPD). PATIENTS AND METHODS: A total of 36 patients (13 males and 23 females), hospitalized in the Nephrology CAPD Center, Peking University Third Hospital, and undergoing intubation and CAPD treatment, were recruited in this study. By utilize a bioelectrical impedance analyzer, changes in extracellular fluid and intracellular fluid within the patients' cells, and overall fluid changes were monitored throughout six months following CAPD treatment...
May 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28612391/yield-resource-use-efficiency-and-trace-metal-uptake-of-weeping-lovegrass-grown-on-municipal-sludge-amended-soil
#10
Eyob H Tesfamariam, John G Annandale, Martin J Steyn, Wayne F Truter, Legesse K Debusho, Deribe G Talore
BACKGROUND: There are concerns that fertilization using sludge in semi-arid areas, where water is limiting, will compound the effect of drought, resulting in the decline of yield from potential salt accumulation. We investigated (8 years) impacts of annual sludge application at 0, 4, 8, and 16 Mg ha(-1) on weeping love grass hay yield, crude protein content (CP), rainfall use efficiency (RUE) and nitrogen use efficiency (NUE), and trace metal uptake. RESULTS: Both hay yield and RUE increased by 5-53% as the sludge rate increased...
June 14, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28611865/dietary-modification-trial-in-community-dwelling-japanese-elderly-a-pilot-study
#11
Chika Momoki, Taeko Tsuji, Yukina Shikata, Hana Urade, Hideki Morimoto, Shinya Nakajima, Daiki Habu
BACKGROUND: This study examined the effects of 6-month nutrition education programs for community-dwelling elderly. METHODS: This study enrolled 50 community-dwelling elderly who regularly visit outpatient clinics. The programs had three goals: salt reduction, increase in dietary fiber, and adequate protein intake. Since it would be difficult for elderly to achieve all goals concurrently, a single goal was chosen by participants themselves. Anthropometric measurements, blood sampling, and assessment of dietary intake were performed at baseline, 3 months, and 6 months...
July 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28608557/salicornia-extract-ameliorates-salt-induced-aggravation-of-nonalcoholic-fatty-liver-disease-in-obese-mice-fed-a-high-fat-diet
#12
Jae Hwan Kim, Sujin Suk, Woo Jung Jang, Chang Hyung Lee, Jong-Eun Kim, Jin-Kyu Park, Mee-Hyang Kweon, Jong Hun Kim, Ki Won Lee
High-fat and high-salt intakes are among the major risks of chronic diseases including obesity, nonalcoholic fatty liver disease (NAFLD), and nonalcoholic steatohepatitis (NASH). Salicornia is a halophytic plant known to exert antioxidant, antidiabetic, and hypolipidemic effects, and Salicornia-extracted salt (SS) has been used as a salt substitute. In this study, the effects of SS and purified salt (PS) on the aggravation of NAFLD/NASH were compared. C57BL/6J male mice (8-wk-old) were fed a high-fat diet (HFD) for 6 mo and divided into 3 dietary groups, which were additionally fed HFD, HFD + SS, and HFD + PS for 13 wk...
June 13, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28604338/intra-individual-variability-in-tsh-levels-of-healthy-women-during-the-first-half-of-pregnancy
#13
Mayte Murillo-Llorente, Carmen Fajardo-Montañana, Marcelino Pérez-Bermejo, Rafael Vila-Candel, José Gómez-Vela, Inés Velasco
OBJECTIVE: TSH is the parameter most widely accepted to assess thyroid function, especially in pregnant women. The aim of this current study was to analyze intra-individual changes in TSH during the first half of pregnancy in women with TSH levels higher than 2.5mIU/L in early pregnancy. METHODS: An observational, prospective study was conducted on 243 healthy pregnant women in the first trimester of pregnancy. Thyroid function was assessed by testing TSH and free T4 levels...
June 2017: Endocrinología, diabetes y nutrición
https://www.readbyqxmd.com/read/28602676/interactions-between-gut-bacteria-and-bile-in-health-and-disease
#14
REVIEW
Sarah L Long, Cormac G M Gahan, Susan A Joyce
Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the liver and the regulatory pathways that influence the composition of the total bile acid pool in the host have been well established. In addition, the gut microbiota provides unique contributions to the diversity of bile acids in the bile acid pool. Gut microbial enzymes contribute significantly to bile acid metabolism through deconjugation and dehydroxylation reactions to generate unconjugated bile acids and secondary bile acids...
June 21, 2017: Molecular Aspects of Medicine
https://www.readbyqxmd.com/read/28598548/eating-behavior-during-dexamethasone-treatment-in-children-with-acute-lymphoblastic-leukemia
#15
Lidewij T Warris, Erica L T van den Akker, Marc B Bierings, Cor van den Bos, Femke K Aarsen, Michel C Zwaan, Wim J E Tissing, Margreet A Veening, Rob Pieters, Marry M van den Heuvel-Eibrink
BACKGROUND AND AIM: Large prospective studies on dexamethasone-induced changes in eating behavior, energy, and nutrient intake are lacking in pediatric acute lymphoblastic leukemia (ALL). We prospectively studied eating behavior, energy, nutrient intake, and the effect on leptin and adiponectin levels during dexamethasone administration in children with ALL. PATIENTS: Parents of patients with ALL (3-16 years) completed a dietary diary for their child during 4 days of dexamethasone (6 mg/m(2) ) administration...
June 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28595781/comparison-of-the-effect-of-dietary-copper-nanoparticles-with-copper-ii-salt-on-bone-geometric-and-structural-parameters-as-well-as-material-characteristics-in-a-rat-model
#16
Ewa Tomaszewska, Siemowit Muszyński, Katarzyna Ognik, Piotr Dobrowolski, Małgorzata Kwiecień, Jerzy Juśkiewicz, Dariusz Chocyk, Michał Świetlicki, Tomasz Blicharski, Bożena Gładyszewska
Copper is required for normal functioning of all basic biochemical and physiological processes in the body. The objective of this study was to compare the effect of two different chemical forms (carbonate and nanoparticles) of Cu administered in feed mixtures to growing rats on bone geometric and structural parameters as well as material characteristics in a rat model. For this purpose, five experimental treatments were used to evaluate the effects of different levels of Cu applied in the diet as a mineral mixture (the standard dose of 6...
July 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/28595525/obesity-induced-hypertension-new-insights
#17
Christina Antza, Stella Stabouli, Michalis Natsis, Ioannis Doundoulakis, Vasilios Kotsis
BACKGROUND: New insights on the relationship between weight loss and hypertension and the role of the newly approved anti-obesity drugs on hypertension will be discussed Methods: Weight loss is a major factor to reduce blood pressure when a patient with excess weight is advised from the health care provider to change his lifestyle. A healthy lifestyle with reduction in body weight, reduction in caloric intake, increased fruit and vegetables consumption and reduced salt intake concomitant with an increase in physical exercise can reduce body weight and hypertension in overweight and obese patients, but not all obese are able to reduce their blood pressure and lose weight without treatment and special dietary care...
June 7, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28594849/high-sodium-diet-converts-renal-proteoglycans-into-pro-inflammatory-mediators-in-rats
#18
Ryanne S Hijmans, Pragyi Shrestha, Kwaku A Sarpong, Saleh Yazdani, Rana El Masri, Wilhelmina H A de Jong, Gerjan Navis, Romain R Vivès, Jacob van den Born
BACKGROUND: High dietary sodium aggravates renal disease by affecting blood pressure and by its recently shown pro-inflammatory and pro-fibrotic effects. Moreover, pro-inflammatory modification of renal heparan sulfate (HS) can induce tissue remodeling. We aim to investigate if high sodium intake in normotensive rats converts renal HS into a pro-inflammatory phenotype, able to bind more sodium and orchestrate inflammation, fibrosis and lymphangiogenesis. METHODS: Wistar rats received a normal diet for 4 weeks, or 8% NaCl diet for 2 or 4 weeks...
2017: PloS One
https://www.readbyqxmd.com/read/28592216/benzoates-intakes-from-non-alcoholic-beverages-in-brazil-canada-mexico-and-the-united-states
#19
Danika M Martyn, Annette A Lau, Maryse N Darch, Ashley S Roberts
Food consumption data from national dietary surveys were combined with brand-specific use levels reported by beverage manufacturers to calculate the exposure to benzoic acid and its salts (INS No 210-213) from non-alcoholic beverages in Brazil, Canada, Mexico and the United States. These four jurisdictions were identified as having some of the highest usages in the world of benzoates in beverages. Use levels were weighted according to the brand's market volume share in the respective countries. Benzoates were reported to be used primarily in 'water-based flavoured drinks' (Codex General Standard for Food Additives (GSFA) category 14...
June 8, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28586308/an-extract-from-the-atlantic-brown-algae-sacchorhiza-polyschides-counteracts-diet-induced-obesity-in-mice-via-a-gut-related-multi-factorial-mechanisms
#20
Patricia Huebbe, Sibylle Nikolai, Anke Schloesser, Diran Herebian, Graeme Campbell, Claus-Christian Glüer, Annette Zeyner, Tobias Demetrowitsch, Karin Schwarz, Cornelia C Metges, Thomas Roeder, Gerhard Schultheiss, Ignacio R Ipharraguerre, Gerald Rimbach
In this study we addressed the questions whether an Atlantic brown algae extract (BAE) affects diet induced obesity in mice and which would be the primary targets and underlying key mechanisms.Male C57 BL/6 mice were fed a hypercaloric diet, referred to as high fat diet (HFD), supplemented with a freeze-dried aqueous BAE from Sacchorizia polyschides (5 %) for 8 months. Compared to the control group, dietary BAE supplementation significantly attenuated increase in body weight and fat mass. We observed apparent metabolic improvement including normalization of blood glucose, reduced plasma leptin, reduced fecal bile salt hydrolase activity with lower microbial production of toxic bile acid metabolites in the gut and increased systemic bile acid circulation in BAE-fed mice counteracting adverse effects of long term HFD feeding...
May 23, 2017: Oncotarget
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