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https://www.readbyqxmd.com/read/29342090/development-of-databases-on-iodine-in-foods-and-dietary-supplements
#1
REVIEW
Abby G Ershow, Sheila A Skeaff, Joyce M Merkel, Pamela R Pehrsson
Iodine is an essential micronutrient required for normal growth and neurodevelopment; thus, an adequate intake of iodine is particularly important for pregnant and lactating women, and throughout childhood. Low levels of iodine in the soil and groundwater are common in many parts of the world, often leading to diets that are low in iodine. Widespread salt iodization has eradicated severe iodine deficiency, but mild-to-moderate deficiency is still prevalent even in many developed countries. To understand patterns of iodine intake and to develop strategies for improving intake, it is important to characterize all sources of dietary iodine, and national databases on the iodine content of major dietary contributors (including foods, beverages, water, salts, and supplements) provide a key information resource...
January 17, 2018: Nutrients
https://www.readbyqxmd.com/read/29335826/high-salt-and-cholesterol-diet-associated-cognitive-impairment-attenuated-by-tannins-enriched-fraction-of-emblica-officinalis-via-inhibiting-nf-kb-pathway
#2
Ibraheem Husain, Mohd Akhtar, Mohammad Shaharyar, Mohammad Islamuddin, Malik Zainul Abdin, Mohd Jawaid Akhtar, Abul Kalam Najmi
Metabolic disorders are closely associated with dietary habits and seem to be related to neuroinflammation and neurodegenerative disease in humans. Emblica officinalis (EOT) fruits not only have good nutritional value but also have excellent therapeutic potential. We used a tannins-enriched fraction of EOT fruit with the expectation of controlling diet-induced neuroinflammation and cognitive impairment in rats. A high-salt and cholesterol diet (HSCD) was used to induce neuroinflammation and cognitive impairment in rats...
January 15, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/29335605/dietary-salt-promotes-neurovascular-and-cognitive-dysfunction-through-a-gut-initiated-th17-response
#3
Giuseppe Faraco, David Brea, Lidia Garcia-Bonilla, Gang Wang, Gianfranco Racchumi, Haejoo Chang, Izaskun Buendia, Monica M Santisteban, Steven G Segarra, Kenzo Koizumi, Yukio Sugiyama, Michelle Murphy, Henning Voss, Joseph Anrather, Costantino Iadecola
A diet rich in salt is linked to an increased risk of cerebrovascular diseases and dementia, but it remains unclear how dietary salt harms the brain. We report that, in mice, excess dietary salt suppresses resting cerebral blood flow and endothelial function, leading to cognitive impairment. The effect depends on expansion of TH17 cells in the small intestine, resulting in a marked increase in plasma interleukin-17 (IL-17). Circulating IL-17, in turn, promotes endothelial dysfunction and cognitive impairment by the Rho kinase-dependent inhibitory phosphorylation of endothelial nitric oxide synthase and reduced nitric oxide production in cerebral endothelial cells...
January 15, 2018: Nature Neuroscience
https://www.readbyqxmd.com/read/29321431/self-reported-slower-eating-is-associated-with-a-lower-salt-intake-a-population-based-cross-sectional-study
#4
Minako Wakasugi, Junichiro James Kazama, Ichiei Narita
Objective Evidence suggests that the eating rate is positively associated with the body weight and blood pressure. Furthermore, people who are overweight or obese tend to have higher salt intakes than those of normal weight. To investigate whether or not the eating rate is also associated with the salt intake, a cross-sectional study was conducted using health examination survey data collected in 2014 from 7,941 residents of Sado City, Niigata, Japan. Methods The eating rates were evaluated using a questionnaire; 11...
January 11, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29321218/non-uniform-relationship-between-salt-status-and-aldosterone-activity-in-patients-with-chronic-kidney-disease
#5
Alison H M Taylor, Alastair J Rankin, Emily P McQuarrie, E Marie Freel, Natalie Z M Homer, Ruth Andrew, Alan G Jardine, Patrick B Mark
BACKGROUND: Hypertension is prevalent in chronic kidney disease (CKD). Studies suggest that reduction in dietary salt intake reduces blood pressure (BP). We studied relationships between salt intake, BP and renin angiotensin system regulation in order to establish if it is disordered in CKD. METHODS: Mechanistic crossover study of CKD patients versus non-CKD controls. Participants underwent modified saline suppression test prior to randomisation to either low or high salt diet for 5 days and then crossed over to the alternate diet...
January 10, 2018: Clinical Science (1979-)
https://www.readbyqxmd.com/read/29315013/on-the-evolution-of-bile-salts-and-the-farnesoid-x-receptor-in-vertebrates
#6
Kim Frisch, Aage Kristian Olsen Alstrup
In recent decades, our knowledge of bile salts has undergone a vast development, and bile salts are now known not only for their detergent properties that aid in the absorption of dietary lipids but also for their interaction with specific nuclear and membrane receptors. In particular, it has been realized that the response of the farnesoid X receptor (FXR) to bile acids provides a signal bridge between the liver and small intestine, controlling the intracellular levels, biosynthesis, and enterohepatic circulation of bile acids...
March 2018: Physiological and Biochemical Zoology: PBZ
https://www.readbyqxmd.com/read/29306348/effect-of-different-dietary-energy-and-protein-sources-on-antioxidant-status-fresh-yolk-fatty-acid-profile-and-microstructure-of-salted-yolks-in-laying-ducks
#7
D Ruan, Y J Hu, A M Fouad, C X Lin, Z P Xu, W Chen, Q L Fan, W G Xia, S Wang, Y Wang, L Yang, C T Zheng
The study investigated whether different dietary energy and protein sources affect laying performance, antioxidant status, fresh yolk fatty acid profile and quality of salted yolks in laying ducks. In all, 360 19-week-old Longyan ducks were randomly assigned to four diets in a factorial arrangement (2×2). The four diets consisted of two energy sources, corn (CO) or sorghum (SO) and two protein sources, soybean meal (SM) and rapeseed meal with corn distillers dried grains with solubles (RMD), and each treatment contained six replicates of 15 birds each...
January 8, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29298567/sodium-excretion-and-associated-factors-in-urine-samples-of-african-descendants-in-alc%C3%A3-ntara-brazil-a-population-based-study
#8
Elisângela Milhomem Dos Santos, Dyego José de Araújo Brito, Isabela Leal Calado, Ana Karina Teixeira França, Joyce Santos Lages, Francisco das Chagas Monteiro Junior, Alcione Miranda Dos Santos, Natalino Salgado Filho
In most countries, salt intake has been excessive and constitutes one of the main risk factors for disease development, especially hypertension. Factors such as age, gender, sedentary lifestyle, smoking, African descent, obesity, dietary habits and family history of hypertension may be associated with high blood pressure. Studies show a positive association between the excretion of sodium and increased blood pressure. We evaluated the urinary excretion of sodium and associated factors in isolated urine samples of African descendants from remaining Quilombos...
November 2018: Renal Failure
https://www.readbyqxmd.com/read/29296095/free-radical-scavenging-reverses-fructose-induced-salt-sensitive-hypertension
#9
Zachary P Zenner, Kevin L Gordish, William H Beierwaltes
We have previously reported that a moderate dietary supplementation of 20% fructose but not glucose leads to a salt-sensitive hypertension related to increased proximal sodium-hydrogen exchanger activity and increased renal sodium retention. We also found that while high salt increased renal nitric oxide formation, this was retarded in the presence of fructose intake. We hypothesized that at least part of the pathway leading to fructose-induced salt-sensitive hypertension could be due to fructose-induced formation of reactive oxygen species and inappropriate stimulation of renin secretion, all of which would contribute to an increase in blood pressure...
2018: Integrated Blood Pressure Control
https://www.readbyqxmd.com/read/29290351/red-meat-intake-in-chronic-kidney-disease-patients-two-sides-of-the-coin
#10
REVIEW
Denise Mafra, Natalia A Borges, Ludmila Ferreira Medeiros de Franca Cardozo, Juliana S Anjos, Ana Paula Black, Cristiane Moraes, Peter Bergman, Bengt Lindholm, Peter Stenvinkel
Red meat is an important dietary source of high biological value protein and micronutrients such as vitamins, iron, and zinc that exert many beneficial functions. However, high consumption of animal protein sources, especially red meat, results in an increased intake of saturated fat, cholesterol, iron, and salt, as well as an excessive acid load. Red meat intake may lead to an elevated production of uremic toxins by the gut microbiota, such as trimethylamine n-oxide (TMAO), indoxyl sulfate, and p-cresyl sulfate...
February 2018: Nutrition
https://www.readbyqxmd.com/read/29288501/optimal-iodine-supplementation-during-anti-thyroid-drug-therapy-for-graves-disease-is-associated-with-lower-recurrence-rates-than-iodine-restriction
#11
Huibin Huang, Yaxiong Shi, Bo Liang, Huiyao Cai, Qingyan Cai, Ruhai Lin
OBJECTIVE: A relationship between iodine intake and the effectiveness of anti-thyroid drug (ATD) therapy for Graves' disease (GD) has been suggested and strict restriction of iodine intake has been tried in the treatment of GD in some studies. However, it is unclear whether dietary iodine supplementation improves the prognosis of ATD therapy for GD. This study aimed to clarify whether optimal iodine supplementation during anti-thyroid drug therapy for GD is associated with lower recurrence rates than iodine restriction...
December 29, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/29285341/simulating-a-virtual-population-s-sensitivity-to-salt-and-uninephrectomy
#12
John S Clemmer, Robert L Hester, W Andrew Pruett
Salt sensitivity, with or without concomitant hypertension, is associated with increased mortality. Reduced functional renal mass plays an important role in causing salt-sensitive hypertension for many individuals. Factors that are important in the condition of decreased renal mass and how they affect blood pressure (BP) or salt sensitivity are unclear. We used HumMod, an integrative mathematical model of human physiology, to create a heterogeneous population of 1000 virtual patients by randomly varying physiological parameters...
February 6, 2018: Interface Focus
https://www.readbyqxmd.com/read/29285159/amelioration-of-the-dss-induced-colitis-in-mice-by-pretreatment-with-4-4-diaponeurosporene-producing-bacillus-subtilis
#13
Yuchao Jing, Haofei Liu, Wenwen Xu, Qian Yang
Inflammatory bowel disease (IBD) is a chronically relapsing inflammatory disorder of the gastrointestinal tract. Current IBD treatments have poor tolerability and insufficient therapeutic efficacy, thus, alternative therapeutic approaches are required. Recently, a number of dietary supplements have emerged as promising interventions. In the present study oral administration of a carotenoid (4,4'-diaponeurosporene)-producing Bacillus subtilis markedly ameliorated dextran sulfate sodium salt-induced mouse colitis, as demonstrated by a reduction in weight loss and the severity of bleeding, which indicated that 4,4'-diaponeurosporene may have beneficial effects on treatments for colitis...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29279360/iodine-intake-from-supplements-and-diet-during-pregnancy-and-child-cognitive-and-motor-development-the-inma-mother-and-child-cohort-study
#14
Mario Murcia, Mercedes Espada, Jordi Julvez, Sabrina Llop, Maria-Jose Lopez-Espinosa, Jesus Vioque, Mikel Basterrechea, Isolina Riaño, Llucia González, Mar Alvarez-Pedrerol, Adonina Tardón, Jesús Ibarluzea, Marisa Rebagliato
BACKGROUND: The effect of mild-to-moderate maternal iodine deficiency on the neuropsychological development of their offspring is uncertain. We aimed to assess the association between iodine status during pregnancy and the cognitive and motor development of children at 4-5 years. METHODS: We conducted a prospective cohort study in four Spanish regions with recruitment of pregnant women between 2003 and 2008 and follow-up of their children up to 4-5 years (mean (SD)=4...
December 26, 2017: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/29278931/cyp1a2-1f-gene-variant-alkaline-salt-tea-intake-and-risk-of-esophageal-squamous-cell-carcinoma
#15
Idrees Ayoub Shah, Promila Mehta, M Maqbool Lone, Malik Tariq Rasool, Ghulam Nabi Lone, G M Gulzar, Farooq Ahmad Ganie, Mohmmad Akbar Bhat, Nazir Ahmad Dar
Unlike many other cancers, the relationship of CYP1A2*1F (rs762551) polymorphism with esophageal squamous cell carcinoma (ESCC) risk has not been assessed so far. To evaluate its association with ESCC, we conducted a case control study in Kashmir, India, a high risk region. We recruited 404 histopathologically confirmed ESCC cases and 404 controls, individually matched for sex, age and residence to the respective cases. Information was obtained on dietary, lifestyle and environmental factors in face to face interviews using a structured questionnaire from each subject...
January 2018: Nutrition and Cancer
https://www.readbyqxmd.com/read/29274435/dietary-cumulative-acute-risk-assessment-of-organophosphorus-carbamates-and-pyrethroids-insecticides-for-the-brazilian-population
#16
Andreia Nunes Oliveira Jardim, Alessandra Page Brito, Gerda van Donkersgoed, Polly E Boon, Eloisa Dutra Caldas
Cumulative acute dietary risk assessments of organophosphorus (OPs), carbamates (CBs) and pyrethroids (PYs) were conducted for the Brazilian population. Residue data for 30786 samples of 30 foods were obtained from two national monitoring programs and one University laboratory, and consumption data from a national survey conducted among persons 10 years or older. Acephate and methamidophos were used as index compounds (IC) for OPs, oxamyl for CBs and deltamethrin for PYs. Exposures were estimated using the Monte Carlo Risk Assessment (MCRA 8...
December 20, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29248540/sodium-butyrate-triggers-a-functional-elongation-of-microglial-process-via-akt-small-rhogtpase-activation-and-hdacs-inhibition
#17
Peng Wang, Yaru Zhang, Yu Gong, Rongrong Yang, Zhuo Chen, Wenfeng Hu, Yue Wu, Minhui Gao, Xing Xu, Yibin Qin, Chao Huang
Microglia, a type of immune cell in the brain, are in a ramified status with branched processes in normal conditions. Upon pathological stimulation, microglia retract their processes and become activated. Searching methods to make the activated microglia return to ramified status would help cope with injuries induced by neuroinflammation. Here, we investigated the influence of sodium butyrate (SB), a sodium salt form of butyrate produced by fermentation of dietary fibers in the gut on microglial process. Results showed that SB induced reversible elongations of microglial process in both normal and inflammatory conditions, and these elongations were accompanied with significant changes in markers reflecting the pro-inflammatory and anti-inflammatory status of microglia...
December 14, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29233499/the-role-of-the-carboxyl-ester-lipase-cel-gene-in-pancreatic-disease
#18
REVIEW
Bente B Johansson, Karianne Fjeld, Khadija El Jellas, Anny Gravdal, Monica Dalva, Erling Tjora, Helge Ræder, Rohit N Kulkarni, Stefan Johansson, Pål R Njølstad, Anders Molven
The enzyme carboxyl ester lipase (CEL), also known as bile salt-dependent or -stimulated lipase (BSDL, BSSL), hydrolyzes dietary fat, cholesteryl esters and fat-soluble vitamins in the duodenum. CEL is mainly expressed in pancreatic acinar cells and lactating mammary glands. The human CEL gene resides on chromosome 9q34.3 and contains a variable number of tandem repeats (VNTR) region that encodes a mucin-like protein tail. Although the number of normal repeats does not appear to significantly influence the risk for pancreatic disease, single-base pair deletions in the first VNTR repeat cause a syndrome of endocrine and exocrine dysfunction denoted MODY8...
December 5, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29233205/effect-of-dietary-habits-on-the-risk-of-metabolic-syndrome-yazd-healthy-heart-project
#19
Mohammadtaghi Sarebanhassanabadi, Seyed Jalil Mirhosseini, Masoud Mirzaei, Seyedeh Mahdieh Namayandeh, Mohammad Hossein Soltani, Mohammadreza Pakseresht, Ali Pedarzadeh, Zahra Baramesipour, Reza Faraji, Amin Salehi-Abargouei
OBJECTIVE: Metabolic syndrome (MetS) refers to a group of risk factors that increase the risk of cardiovascular mortality and morbidity. Dietary habits are among the most important risk factors for MetS. The current study aimed at assessing the effect of dietary habits on the risk of MetS in a 10-year follow-up study in central Iran. DESIGN: Cohort study. SETTING: Yazd, Iran. SUBJECTS: Participants aged 20-74 years without any history of MetS, who were originally recruited for Yazd Healthy Heart Project (YHHP) during 2005-2006, were revisited during 2015-2016...
December 13, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/29232668/revised-reference-values-for-the-intake-of-sodium-and-chloride
#20
Daniela Strohm, Angela Bechthold, Sabine Ellinger, Eva Leschik-Bonnet, Peter Stehle, Helmut Heseker
BACKGROUND: In January 2017, the nutrition societies of -Germany, Austria and Switzerland revised the reference values for sodium and chloride intake. METHODS: For adults, the estimated value for sodium intake was derived on the basis of a balance study. The estimated values for children and adolescents were extrapolated from this estimated value considering differences in body mass. For infants aged 0 to under 4 months, an estimated value was set based on the sodium intake via breast milk...
December 12, 2017: Annals of Nutrition & Metabolism
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