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MMPI-2 and Epilepsy

Antonietta Coppola, Carmela Caccavale, Lia Santulli, Simona Balestrini, Claudia Cagnetti, Laura Licchetta, Marcello Esposito, Francesca Bisulli, Paolo Tinuper, Leandro Provinciali, Carlo Minetti, Federico Zara, Pasquale Striano, Salvatore Striano
OBJECTIVE: The objective of this report was to assess the psychiatric comorbidity in a group of patients affected by autosomal dominant cortical tremor, myoclonus, and epilepsy (ADCME). METHODS: Reliable and validated psychodiagnostic scales including the BDI (Beck Depression Inventory), STAI-Y1 and 2 (State-Trait Anxiety Inventory - Y; 1 and 2), MMPI-2 (Minnesota Multiphasic Personality Inventory - 2), and QoLIE-31 (Quality of Life in Epilepsy Inventory - 31) were administered to 20 patients with ADCME, 20 patients with juvenile myoclonic epilepsy (JME), and 20 healthy controls...
March 2016: Epilepsy & Behavior: E&B
Rebecca E Wershba, Dona E C Locke, Richard I Lanyon
The use of response bias indicators in psychological measurement has been contentious, with debate as to whether they actually suppress or moderate the ability of substantive psychological indicators to identify the construct of interest. Suppression would indicate that predictor variables contain invalid variance that the bias indicators can suppress, while moderation would indicate differential levels of predictive validity at different levels of bias. Response bias indicators on the Minnesota Multiphasic Personality Inventory (MMPI)-2-Restructured Form (MMPI-2-RF) [infrequent responses (F-r), infrequent somatic responses (Fs), infrequent psychopathology responses (Fp-r), adjustment validity (K-r), uncommon virtues (L-r), symptom validity (FBS-r), and Response Bias Scale (RBS)] were tested to determine whether they suppressed or moderated the ability of the Restructured Clinical Scale 1 (RC1) and Neurologic Complaints (NUC) scale to discriminate between epileptic seizures (ES) and nonepileptic seizures (NES, a conversion disorder that is often misdiagnosed as ES)...
June 2015: Psychological Assessment
Stephen C Bowden, Jessica R White, Leonie Simpson, Yossef S Ben-Porath
PURPOSE: People with seizure disorders experience elevated rates of psychopathology, often undiagnosed and untreated. Accurate diagnosis of psychopathology remains an important goal of quality health care for people with seizure disorders. One of the most widely used dimensional measures of psychopathology is the Minnesota Multiphasic Personality Inventory-Second Edition (MMPI-2). Research in heterogeneous mental health samples suggests that the 2008 revision of this measure, the Minnesota Multiphasic Personality Inventory-Second Edition-Restructured Form (MMPI-2-RF), offers better construct fidelity and more cost-effective administration...
May 2014: Epilepsy & Behavior: E&B
Sören Kliem, Johannes Beller, Christoph Kröger, Tobias Birowicz, Markus Zenger, Elmar Brähler
Somatoform disorders are characterized by somatic symptoms that suggest a medical condition when such a condition is not present. Recently, Thomas and Locke (2010) and Jasper, Hiller, Rist, Bailer, and Witthöft (2012) found that the latent status of somatic symptom reporting may be best viewed from a dimensional perspective in a student, primary care, and an epilepsy-monitoring-unit setting using the Minnesota Multiphasic Personality Inventory-2-Restructured Form Somatic Complaints (RC1) Scale and Patient Health Questionnaire (PHQ-15)...
June 2014: Psychological Assessment
A del Barrio, A Jiménez-Huete, R Toledano, I García-Morales, A Gil-Nagel
INTRODUCTION: The use of the Multiphasic Personality Inventory Minnesota 2 (MMPI-2) for the diagnosis of psychogenic non-epileptic seizures (PNES) is controversial. This study examines the validity of the clinical scales and, unlike previous works, the content scales. METHODS: Cross-sectional study of 209 patients treated in the epilepsy unit. We performed a logistic regression analysis, taking video-electroencephalography as the reference test, and as predictor variables age, sex, IQ and clinical (model A) or content scales (model B) of the MMPI-2...
March 2016: Neurología: Publicación Oficial de la Sociedad Española de Neurología
Brandee E Goodwin, Martin Sellbom, Paul A Arbisi
The current investigation examined the utility of the overreporting validity scales of the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008) in detecting noncredible reporting of symptoms of posttraumatic stress disorder (PTSD) in a sample of disability-seeking veterans. We also examined the effect of mental health knowledge on the utility of these scales by investigating the extent to which these scales differentiate between veterans with PTSD and individuals with mental health training who were asked to feign symptoms of PTSD on the test...
September 2013: Psychological Assessment
Amie Foran, Stephen Bowden, Fiona Bardenhagen, Mark Cook, Catherine Meade
An investigation into the specificity of psychopathology in temporal lobe epilepsy was conducted using the Minnesota Multiphase Personality Inventory second edition (MMPI-2) profiles. Consecutive series of patients with left temporal lobe epilepsy (n = 49) and those with right temporal lobe epilepsy (n = 45) were compared with patients with other forms of epilepsy (n = 46) and other heterogeneous neurological conditions (n = 69). The investigation focused on the Clinical, Content, and Subscales scales that resembled descriptions of the Interictal Dysphoric Disorder symptoms and Temporal Lobe Epilepsy Personality Traits...
April 2013: Epilepsy & Behavior: E&B
Shawn D Gale, Stacy W Hill
The Minnesota Multiphasic Personality Inventory-second edition (MMPI-2) and the Personality Assessment Inventory (PAI) are commonly used in the epilepsy monitoring unit (EMU) to evaluate personality characteristics and mood-related symptoms in those individuals being evaluated for epileptic seizures (ES) or psychogenic non-epileptic seizures (PNES). A direct comparison of these measures through concurrent administration to the same group has not been carried out. Both measures were administered to 40 patients (17 ES and 23 PNES)...
October 2012: Epilepsy & Behavior: E&B
Ryan W Schroeder, Lyle E Baade, Caleb P Peck, Emanuel J VonDran, Callie J Brockman, Blake K Webster, Robin J Heinrichs
This study utilized multiple criterion group neuropsychological samples to evaluate the "over-reporting" and "under-reporting" MMPI-2-RF validity scales. The five criterion groups included in this study were (1) litigating traumatic brain injury patients who failed Slick et al. criteria for probable malingering, (2) litigating traumatic brain injury patients who passed Slick et al. criteria, (3) mixed neuropsychological outpatients who passed SVTs and were diagnosed with primary neurological conditions, (4) mixed neuropsychological outpatients who passed SVTs and were diagnosed with primary psychiatric conditions, and (5) epileptic seizure disorder inpatients who were diagnosed via video-EEG...
2012: Clinical Neuropsychologist
Dona E C Locke, Kristin A Kirlin, Rebecca Wershba, David Osborne, Joseph F Drazkowski, Joseph I Sirven, Katherine H Noe
The two most common personality measures used in evaluation of patients on epilepsy monitoring units (EMUs) are the Personality Assessment Inventory (PAI) and the Minnesota Multiphasic Personality Inventory-2 (MMPI-2). Both have been evaluated separately for their ability to distinguish patients with epilepsy from patients with psychogenic events, but they have never been compared directly. The primary aim of this study was to provide comparison data in an EMU population between the PAI, MMPI-2, and the MMPI-2-RF (MMPI-2 Restructured Form)...
August 2011: Epilepsy & Behavior: E&B
Dona E C Locke, Michael L Thomas
Long term video-EEG (electroencephalography) monitoring in an epilepsy monitoring unit (EMU) will remain the gold standard for differential diagnosis of epilepsy from psychogenic nonepileptic seizures. However, neuropsychologists are routinely part of the differential diagnosis team and utilize personality assessment measures to add supportive data for the diagnosis. The most accurate scale on the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) in terms of differential diagnosis appears to be RC1 (Somatic Complaints) with a classification rate of 68% (Locke et al...
March 2011: Journal of Clinical and Experimental Neuropsychology
Michael L Thomas, Dona E C Locke
The MMPI-2 Restructured Form (MMPI-2-RF; Tellegen & Ben-Porath, 2008) was designed to be psychometrically superior to its MMPI-2 counterpart. However, the test has yet to be extensively evaluated in diverse clinical settings. The purpose of this study was to examine the psychometric properties of the MMPI-2-RF Somatic Complaints (RC1) scale in a clinically relevant population. Participants were 399 patients diagnosed with either epilepsy or psychogenic nonepileptic seizures on the basis of video-electroencephalograph monitoring...
September 2010: Psychological Assessment
Kiely M Donnelly, Bruce K Schefft, Steven R Howe, Jerzy P Szaflarski, Hwa-shain Yeh, Michael D Privitera
Stress is a commonly reported seizure precipitant among individuals with epilepsy. Yet, the relationship between stress and seizure susceptibility remains unclear. This study examined the relationship between emotional distress and lifetime seizure load in individuals with temporal lobe epilepsy (TLE), as well as the potential moderating effect of explanatory style on this relationship. Data were collected from 148 individuals with TLE. Scales 2 and 7 of the Minnesota Multiphasic Personality Inventory were used as a measure of emotional distress, and explanatory style was measured using the Revised Optimism-Pessimism Scale...
August 2010: Epilepsy & Behavior: E&B
Maya J Ramirez, Bruce K Schefft, Steven R Howe, Christine Hovanitz, Hwa-shain Yeh, Michael D Privitera
We evaluated the potential moderating effect of emotional distress (Minnesota Multiphasic Personality Inventory 2, scales D and Pt) on language functioning (i.e., Boston Naming Test, phonemic paraphasic error production on the Boston Naming Test, Controlled Oral Word Association Task, Animal Naming, Token Test) in patients with left (N=43) and right (N=34) mesial temporal lobe epilepsy (MTLE) and frontal lobe epilepsy (FLE) (N=30). Video/EEG and brain imaging results confirmed localization. Logistic regression models revealed that perceived emotional distress moderated language performance...
May 2010: Epilepsy & Behavior: E&B
Dona E C Locke, Kristin A Kirlin, Michael L Thomas, David Osborne, Duane F Hurst, Joseph F Drazkowski, Joseph I Sirven, Katherine H Noe
The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) is a restructuring of the MMPI-2 that has improved the psychometric characteristics of the test. The primary aim of this study was to provide diagnostic utility data on the MMPI-2-RF in an epilepsy monitoring unit population (N=429). Mean comparisons revealed group differences on Validity Scales Fs and FBS-r; Restructured Clinical Scales RC1 and RC3; and Somatic Scales MLS, GIC, HPC, and NUC. Diagnostic utility data are provided for those scales with the largest effect sizes: RC1, FBS-r, and NUC...
February 2010: Epilepsy & Behavior: E&B
Dona E C Locke, Toufic A Fakhoury, David T R Berry, Trey R Locke, Frederick A Schmitt
Previous research has been equivocal on personality trait and psychopathology differences between temporal lobe and other types of epilepsy, as well as between patients with right and left temporal lobe seizure foci. In this study, personality differences between patients with right temporal (n=23), left temporal (n=21), and extratemporal (n=24) epilepsy were investigated using the NEO Personality Inventory-Revised (NEO-PI-R). No statistically significant differences were found on any of the NEO-PI-R domains or facet trait scales...
February 2010: Epilepsy & Behavior: E&B
Amy L Johnson, Daniel Storzbach, Laurence M Binder, André Barkhuizen, W Kent Anger, Martin C Salinsky, Saw-Myo Tun, Diane S Rohlman
We compared MMPI-2 profiles of Gulf War veterans with fibromyalgia (FM) to epileptic seizure (ES) patients, psychogenic non-epileptic seizure (PNES) patients, and Gulf War veteran healthy controls. Both PNES and FM are medically unexplained conditions. In previous MMPI-2 research PNES patients were shown to have significantly higher Hs and Hy clinical scales than ES patients. In the present research the FM group had significantly higher Hs and Hy scale scores than both the ES group and the healthy control group...
February 2010: Clinical Neuropsychologist
Jesse G Brand, Leslie A Burton, Sarah G Schaffer, Kenneth R Alper, Orrin Devinsky, William B Barr
The current study examined the relationship between emotional recognition and depression using the Minnesota Multiphasic Personality Inventory, Second Edition (MMPI-2), in a population with epilepsy. Participants were a mixture of surgical candidates in addition to those receiving neuropsychological testing as part of a comprehensive evaluation. Results suggested that patients with epilepsy reporting increased levels of depression (Scale D) performed better than those patients reporting low levels of depression on an index of simple facial recognition, and depression was associated with poor prosody discrimination...
July 2009: Epilepsy & Behavior: E&B
Hillary Russell, Erica L Coady, Naomi Chaytor
This study examined the impact of seizure-related items and selected comorbid medical conditions on Minnesota Multiphasic Personality Inventory, Second Edition (MMPI-2), Scales 1 and 3 and the psychogenic nonepileptic seizure (PNES) profile [Wilkus RJ, Dodrill CB, Thompson PM. Intensive EEG monitoring and psychological studies of patients with pseudoepileptic seizures. Epilepsia 1984;25:100-7] in patients with epileptic seizures (ES) and PNES. Sixty patients with a long-term video/EEG monitoring diagnosis of either ES (N=30) or PNES (N=30) and valid MMPI-2 profiles were included in this study...
July 2009: Epilepsy & Behavior: E&B
Marianna Mazza, Giacomo Della Marca, Annalisa Martini, Marta Scoppetta, Catello Vollono, Maria Azzurra Valenti, Maria Luigia Vaccario, Pietro Bria, Salvatore Mazza
OBJECTIVES: (1) To measure depressive and dissociative symptoms in a population of patients with Non-Epileptic Seizures (NES, or pseudo-seizures); (2) To compare NES with Epileptic subjects and Normal controls; (3) To try to define a personality profile specific, or typical, of NES patients. METHODS: HASH(0x397d198) PATIENTS: 30 consecutive patients (21 females and 9 males, mean age 32.9+/-11.7 years) with NES diagnosed on clinical basis and confirmed by video-EEG recording; 30 patients with epilepsy matched for age and sex who had presented at least two seizures in the 12 months prior to the study despite pharmacological treatment; 30 Control subjects, healthy volunteers, matched for age and sex...
April 2009: Epilepsy Research
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