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https://www.readbyqxmd.com/read/28207775/the-contribution-of-gender-based-violence-and-network-trauma-to-gender-differences-in-post-traumatic-stress-disorder
#1
Derrick Silove, Jess R Baker, Mohammed Mohsin, Maree Teesson, Mark Creamer, Meaghan O'Donnell, David Forbes, Natacha Carragher, Tim Slade, Katherine Mills, Richard Bryant, Alexander McFarlane, Zachary Steel, Kim Felmingham, Susan Rees
BACKGROUND: Posttraumatic stress disorder (PTSD) occurs twice as commonly amongst women as men. Two common domains of trauma, network trauma and gender based violence (GBV), may contribute to this gender difference in PTSD rates. We examined data from a nationally representative sample of the Australian population to clarify the characteristics of these two trauma domains in their contributions to PTSD rates in men and women. METHODS: We drew on data from the 2007 Australian National Survey of Mental Health and Well-being to assess gender differences across a comprehensive range of trauma domains, including (1) prevalence of lifetime exposure; (2) identification of an index trauma or DSM-IV Criterion A event; and (3) the likelihood of developing full DSM-IV PTSD symptoms once an index trauma was identified...
2017: PloS One
https://www.readbyqxmd.com/read/28202713/vitamin-d-supplementation-to-prevent-acute-respiratory-tract-infections-systematic-review-and-meta-analysis-of-individual-participant-data
#2
Adrian R Martineau, David A Jolliffe, Richard L Hooper, Lauren Greenberg, John F Aloia, Peter Bergman, Gal Dubnov-Raz, Susanna Esposito, Davaasambuu Ganmaa, Adit A Ginde, Emma C Goodall, Cameron C Grant, Christopher J Griffiths, Wim Janssens, Ilkka Laaksi, Semira Manaseki-Holland, David Mauger, David R Murdoch, Rachel Neale, Judy R Rees, Steve Simpson, Iwona Stelmach, Geeta Trilok Kumar, Mitsuyoshi Urashima, Carlos A Camargo
Objectives To assess the overall effect of vitamin D supplementation on risk of acute respiratory tract infection, and to identify factors modifying this effect.Design Systematic review and meta-analysis of individual participant data (IPD) from randomised controlled trials.Data sources Medline, Embase, the Cochrane Central Register of Controlled Trials, Web of Science, ClinicalTrials.gov, and the International Standard Randomised Controlled Trials Number registry from inception to December 2015.Eligibility criteria for study selection Randomised, double blind, placebo controlled trials of supplementation with vitamin D3 or vitamin D2 of any duration were eligible for inclusion if they had been approved by a research ethics committee and if data on incidence of acute respiratory tract infection were collected prospectively and prespecified as an efficacy outcome...
February 15, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28196949/referral-pathways-for-patients-with-tia-avoiding-hospital-admission-a-scoping-review
#3
Bridie Angela Evans, Khalid Ali, Jenna Bulger, Gary A Ford, Matthew Jones, Chris Moore, Alison Porter, Alan David Pryce, Tom Quinn, Anne C Seagrove, Helen Snooks, Shirley Whitman, Nigel Rees
OBJECTIVE: To identify the features and effects of a pathway for emergency assessment and referral of patients with suspected transient ischaemic attack (TIA) in order to avoid admission to hospital. DESIGN: Scoping review. DATA SOURCES: PubMed, CINAHL Web of Science, Scopus. STUDY SELECTION: Reports of primary research on referral of patients with suspected TIA directly to specialist outpatient services. DATA EXTRACTION: We screened studies for eligibility and extracted data from relevant studies...
February 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28192993/quantitative-affinity-determination-by-fluorescence-anisotropy-measurements-of-individual-nanoliter-droplets
#4
Fabrice Gielen, Maren Butz, Eric J Rees, Miklos Erdelyi, Tommaso Moschetti, Marko Hyvönen, Joshua B Edel, Clemens F Kaminski, Florian Hollfelder
Fluorescence anisotropy measurements of reagents compartmentalized into individual nanoliter droplets are shown to yield high-resolution binding curves from which precise dissociation constants (Kd) for protein-peptide interactions can be inferred. With the current platform, four titrations can be obtained per minute (based on ∼100 data points each), with stoichiometries spanning more than 2 orders of magnitude and requiring only tens of microliters of reagents. In addition to affinity measurements with purified components, Kd values for unpurified proteins in crude cell lysates can be obtained without prior knowledge of the concentration of the expressed protein, so that protein purification can be avoided...
January 17, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28186396/immobilization-of-2-deoxy-d-ribose-5-phosphate-aldolase-in-polymeric-thin-films-via-the-langmuir-schaefer-technique
#5
Stefan Reinicke, Huw Conor Rees, Pieter Espeel, Nane Vanparijs, Carolin Bisterfeld, Markus Dick, Ruben R Rosencrantz, Gerald Brezesinski, Bruno G De Geest, Filip E Du Prez, Jörg Pietruszka, Alexander Böker
A synthetic protocol for the fabrication of ultrathin polymeric films containing the enzyme 2-deoxy-D-ribose-5-phosphate aldolase from Escherichia. coli (DERAEC) is presented. Ultrathin enzymatically active films are useful for applications in which only small quantities of active material are needed and at the same time quick response and contact times without diffusion limitation are wanted. We show how DERA as an exemplary enzyme can be immobilized in a thin polymer layer at the air-water interface, and transferred to a suitable support by the Langmuir-Schaefer technique under full conservation of enzymatic activity...
February 10, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28185350/development-of-a-strategy-for-the-total-chemical-synthesis-of-an-allergenic-protein-the-peach-ltp-pru-p-3
#6
Sofie Buhler, Jaap H Akkerdaas, Thelma A Pertinhez, Ronald Van Ree, Arnaldo Dossena, Stefano Sforza, Tullia Tedeschi
The possibility to obtain allergenic proteins by means of total chemical synthesis would be a big step forward in the development of cures to food allergy and in the study of the mechanism of allergic reactions, because this would allow to achieve control at the molecular level over the structure of the product and to study its relationship with the allergenic activity in fine details. This is instead not possible by using allergens produced by extraction from natural sources or by recombinant DNA techniques...
February 10, 2017: Journal of Peptide Science: An Official Publication of the European Peptide Society
https://www.readbyqxmd.com/read/28179164/metacognitive-ability-correlates-with-hippocampal-and-prefrontal-microstructure
#7
Micah Allen, James C Glen, Daniel Müllensiefen, Dietrich Samuel Schwarzkopf, Francesca Fardo, Darya Frank, Martina F Callaghan, Geraint Rees
The ability to introspectively evaluate our experiences to form accurate metacognitive beliefs, or insight, is an essential component of decision-making. Previous research suggests individuals vary substantially in their level of insight, and that this variation is related to brain volume and function, particularly in the anterior prefrontal cortex (aPFC). However, the neurobiological mechanisms underlying these effects are unclear, as qualitative, macroscopic measures such as brain volume can be related to a variety of microstructural features...
February 4, 2017: NeuroImage
https://www.readbyqxmd.com/read/28177145/social-class-dementia-and-the-fourth-age
#8
Ian Rees Jones
Research addressing social class and dementia has largely focused on measures of socioeconomic status as causal risk factors for dementia and in observed differences in diagnosis, treatment and care. This large body of work has produced important insights but also contains numerous problems and weaknesses. Research needs to take account of the ways in which ageing and social class have been transformed in tandem with the economic, social and cultural coordinates of late modernity. These changes have particular consequences for individual identities and social relations...
February 2017: Sociology of Health & Illness
https://www.readbyqxmd.com/read/28173043/p787-the-microbiota-and-it-s-role-in-anti-tnf-therapy-non-response
#9
N S Ding, A Perdones-Montero, M Sarafian, D Rees, L Penez, E Holmes, J Marchesi, A Hart
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28171881/neurotoxicity-from-immune-checkpoint-inhibition-in-the-treatment-of-melanoma-a-single-centre-experience-and-review-of-the-literature
#10
L Spain, G Walls, M Julve, K O'Meara, T Schmid, E Kalaitzaki, S Turajlic, M Gore, J Rees, J Larkin
No abstract text is available yet for this article.
October 25, 2016: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/28168210/white-matter-predicts-functional-connectivity-in-premanifest-huntington-s-disease
#11
Peter McColgan, Sarah Gregory, Adeel Razi, Kiran K Seunarine, Fatma Gargouri, Alexandra Durr, Raymund A C Roos, Blair R Leavitt, Rachael I Scahill, Chris A Clark, Sarah J Tabrizi, Geraint Rees, A Coleman, J Decolongon, M Fan, T Petkau, C Jauffret, D Justo, S Lehericy, K Nigaud, R Valabrègue, A Choonderbeek, E P T Hart, D J Hensman Moss, H Crawford, E Johnson, M Papoutsi, C Berna, R Reilmann, N Weber, J Stout, I Labuschagne, B Landwehrmeyer, M Orth, H Johnson
OBJECTIVES: The distribution of pathology in neurodegenerative disease can be predicted by the organizational characteristics of white matter in healthy brains. However, we have very little evidence for the impact these pathological changes have on brain function. Understanding any such link between structure and function is critical for understanding how underlying brain pathology influences the progressive behavioral changes associated with neurodegeneration. Here, we demonstrate such a link between structure and function in individuals with premanifest Huntington's...
February 2017: Annals of Clinical and Translational Neurology
https://www.readbyqxmd.com/read/28163926/rapid-analgesia-for-prehospital-hip-disruption-rapid-protocol-for-feasibility-study-of-randomised-controlled-trial
#12
Jenna K Bulger, Alan Brown, Bridie A Evans, Greg Fegan, Simon Ford, Katy Guy, Sian Jones, Leigh Keen, Ashrafunnesa Khanom, Ian Pallister, Nigel Rees, Ian T Russell, Anne C Seagrove, Helen A Snooks
BACKGROUND: Adequate pain relief at the point of injury and during transport to hospital is a major challenge in all acute traumas, especially for those with hip fractures, whose injuries are difficult to immobilise and whose long-term outcomes may be adversely affected by administration of opiate analgesics. Fascia iliaca compartment block (FICB) is a procedure routinely undertaken by doctors and nurses in the emergency department for patients with hip fracture but not yet evaluated for use by paramedics at the scene of emergency calls...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/28163316/prediction-and-evaluation-of-resting-energy-expenditure-in-a-large-group-of-obese-outpatients
#13
M Marra, I Cioffi, R Sammarco, C Montagnese, M Naccarato, V Amato, F Contaldo, F Pasanisi
BACKGROUND/OBJECTIVES: The aim of this study was to compare resting energy expenditure (REE) measured (MREE) by indirect calorimetry (IC) and REE predicted (PREE) from established predictive equations in a large sample of obese Caucasian adults. SUBJECTS/METHODS: We evaluated 1851 obese patients (BMI>30 kg/m(2)) aged between 18-65 years. Data were obtained by comparing MREE with PREE, derived from different equations, within and between normal weight and obese groups...
February 6, 2017: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/28161630/base-pair-opening-dynamics-of-the-microrna-precursor-pri-mir156a-affect-temperature-responsive-flowering-in-arabidopsis
#14
Hee-Eun Kim, Wanhui Kim, Ae-Ree Lee, Suhyun Jin, A Rim Jun, Nak-Kyoon Kim, Joon-Hwa Lee, Ji Hoon Ahn
Internal and environmental cues, including ambient temperature changes, regulate the timing of flowering in plants. Arabidopsis miR156 represses flowering and plays an important role in the regulation of temperature-responsive flowering. However, the molecular basis of miR156 processing at lower temperatures remains largely unknown. Here, we performed nuclear magnetic resonance studies to investigate the base-pair opening dynamics of model RNAs at 16 °C and investigated the in vivo effects of the mutant RNAs on temperature-responsive flowering...
February 1, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28159463/the-incidence-and-aetiology-of-acute-pancreatitis-across-europe
#15
REVIEW
Stephen E Roberts, Sian Morrison-Rees, Ann John, John G Williams, Tim H Brown, David G Samuel
BACKGROUND: Acute pancreatitis is increasingly one of the most important acute gastrointestinal conditions throughout much of the world, although incidence and aetiology varies across countries and regions. This study investigated regional and national patterns in the incidence and aetiology of acute pancreatitis, demographic patterns in incidence and trends over time in incidence across Europe. METHODS: A structured review of acute pancreatitis incidence and aetiology from studies of hospitalised patient case series, cohort studies or other population based studies from 1989 to 2015 and a review of trends in incidence from 1970 to 2015 across all 51 European states...
January 19, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/28158697/script-in-a-day-intervention-for-individuals-who-are-injecting-opioids-a-feasibility-randomized-control-trial
#16
Angela Beattie, Elsa M R Marques, Matthew Barber, Rosemary Greenwood, Jennifer Ingram, Rachel Ayres, Jane Neale, Avril Rees, Barbara Coleman, Matthew Hickman
No abstract text is available yet for this article.
December 2, 2016: Journal of Public Health
https://www.readbyqxmd.com/read/28156129/effects-of-citric-acid-and-the-siderophore-desferrioxamine-b-dfo-b-on-the-mobility-of-germanium-and-rare-earth-elements-in-soil-and-uptake-in-phalaris-arundinacea
#17
Oliver Wiche, Dirk Tischler, Carla Fauser, Jana Lodemann, Hermann Heilmeier
Effects of citric acid and desferrioxamine B (DFO-B) on the availability of Ge and selected REEs (La, Nd, Gd, Er) to P. arundinacea were investigated. A soil dissolution experiment was conducted to elucidate the effect of citric acid and DFO-B at different concentrations (1 and 10 mmol l(-1) citric acid) on the release of Ge and REEs from soil. In a greenhouse plants of P. arundinacea were cultivated on soil and on sand cultures to investigate the effects of citric acid and DFO-B on the uptake of Ge and REEs by the plants...
February 3, 2017: International Journal of Phytoremediation
https://www.readbyqxmd.com/read/28155184/blood-product-transfusion-in-emergency-department-patients-a-case-control-study-of-practice-patterns-and-impact-on-outcome
#18
Alexander Beyer, Ryan Rees, Christopher Palmer, Brian T Wessman, Brian M Fuller
BACKGROUND: Blood product transfusion occurs in a significant percentage of intensive care unit (ICU) patients. Pulmonary complications, such as acute respiratory distress syndrome (ARDS), occurring in the setting of transfusion, are associated with increased morbidity and mortality. Contrary to the ICU setting, there is little evidence describing the epidemiology of transfusion in the emergency department (ED) or its potential impact on outcome. The objectives of this study were to: (1) characterize transfusion practices in the ED with respect to patient characteristics and pre-transfusion laboratory values; and (2) investigate the effect of ED blood product transfusion on the incidence of pulmonary complications after admission...
December 2017: International Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28154874/comparative-electronic-structures-of-nitrogenase-femoco-and-fevco
#19
Julian A Rees, Ragnar Bjornsson, Joanna K Kowalska, Frederico A Lima, Julia Schlesier, Daniel Sippel, Thomas Weyhermüller, Oliver Einsle, Julie A Kovacs, Serena DeBeer
An investigation of the active site cofactors of the molybdenum and vanadium nitrogenases (FeMoco and FeVco) was performed using high-resolution X-ray spectroscopy. Synthetic heterometallic iron-sulfur cluster models and density functional theory calculations complement the study of the MoFe and VFe holoproteins using both non-resonant and resonant X-ray emission spectroscopy. Spectroscopic data show the presence of direct iron-heterometal bonds, which are found to be weaker in FeVco. Furthermore, the interstitial carbide is found to perturb the electronic structures of the cofactors through highly covalent Fe-C bonding...
February 3, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28145879/late-double-barrel-lumen-following-successful-cto-pci-using-the-crossboss-stingray-system
#20
James Roy, David Rees, David Ramsay, James Weaver
There remains limited randomized controlled trials on long-term clinical outcomes after chronic total occlusion percutaneous coronary intervention (CTO-PCI). New techniques involving dissection of the subintimal space and reentry into the true lumen increase success rates in CTO-PCI. However, their longer-term safety and efficacy remain unknown and poorly studied. We present a case of double-lumen formation seen at 1 year post CTO-PCI using subintimal dissection reentry with late restoration of major side branches...
February 2017: Journal of Invasive Cardiology
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