keyword
MENU ▼
Read by QxMD icon Read
search

EN

keyword
https://www.readbyqxmd.com/read/28437354/complete-spondylectomy-using-orthogonal-spinal-fixation-and-combined-anterior-and-posterior-approaches-for-thoracolumbar-spinal-reconstruction-technical-nuances-and-clinical-results
#1
Hasan A Zaidi, Al-Wala Awad, Curtis A Dickman
STUDY DESIGN: Retrospective chart review. OBJECTIVE: To determine the long-term efficacy of 2-stage total en bloc spondylectomy (TES). SUMMARY OF BACKGROUND DATA: TES is a well-described technique to achieve tumor-free margins, but it is a highly destabilizing procedure that necessitates spinal reconstruction. A 2-stage anterior/posterior approach for tumor resection and instrumentation has been shown to be biomechanically superior to the single-stage approach in achieving rigid fixation, but few clinical studies with long-term outcomes exist...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28436851/synergistic-pet-and-sense-mr-image-reconstruction-using-joint-sparsity-regularization
#2
Abolfazl Mehranian, Martin Belzunce, Claudia Prieto, Alexander Hammers, Andrew Reader
In this work we propose a generalized joint sparsity regularization prior and reconstruction framework for the syner-gistic reconstruction of PET and undersampled sensitivity en-coded (SENSE) MRI data with the aim of improving image quality beyond that obtained through conventional independent recon-structions. The proposed prior improves upon the joint total vari-ation (TV) using a non-convex potential function that assigns a rel-atively lower penalty for the PET and MR gradients whose mag-nitudes are jointly large, thus permitting the preservation and for-mation of common boundaries irrespective of their relative orien-tation...
April 18, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28436567/an-ultrastructural-study-of-chondroptosis-programmed-cell-death-in-degenerative-intervertebral-discs-in%C3%A2-vivo
#3
Li-Bo Jiang, Hai-Xiao Liu, Yu-Long Zhou, Sun-Ren Sheng, Hua-Zi Xu, En-Xing Xue
Apoptosis has been regarded to mediate intervertebral disc degeneration (IDD); however, the basic question of how the apoptotic bodies are cleared in the avascular intervertebral disc without phagocytes, which are essential to apoptosis, remains to be elucidated. Our goals were to investigate the ultrastructure of nucleus pulposus (NP) cells undergoing chondroptosis, a variant of apoptotic cell death, in a rabbit annular needle-puncture model of IDD. Experimental IDD was induced by puncturing discs with a 16-G needle in New Zealand rabbits...
April 24, 2017: Journal of Anatomy
https://www.readbyqxmd.com/read/28435724/crystal-structures-of-two-platinum-ii-complexes-containing-ethyl-eugenoxyacetate-and-2-amino-pyridine
#4
Hai Le Thi Hong, Thao Nguyen Thu, Hien Nguyen, Luc Van Meervelt
In the title complexes, trans-(2-amino-pyridine-κN)di-chlorido-{4-eth-oxy-carbonyl-meth-oxy-3-meth-oxy-1-[(2,3-η)-prop-2-en-1-yl]benzene}-platinum(II), [PtCl2(C5H6N2)(C14H18O4)], (I), and (2-amino-pyridine-κN)chlorido{5-eth-oxy-car-bon-yl-meth-oxy-4-meth-oxy-1-[(2,3-η)-prop-2-en-1-yl]phenyl-κC(1)}-platinum(II), [Pt(C14H17O4)Cl(C5H6N2)], (II), the central Pt(II) metal atom displays a distorted square-planar coordination, with the Pt(II) atom coordinated by the pyridine N atom, the C=C double bond of the eugenol ligand and two Cl atoms for (I) or one Cl atom and a C atom of the phenyl ring for (II)...
April 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28435701/crystal-structure-of-2e-3-4-di-methyl-amino-phen-yl-1-thio-phen-2-yl-prop-2-en-1-one
#5
Gabriela Porto de Oliveira, Leandro Bresolin, Darlene Correia Flores, Renan Lira de Farias, Adriano Bof de Oliveira
The equimolar reaction between 4-(di-methyl-amino)-benzaldehyde and 2-acetyl-thio-phene in basic ethano-lic solution yields the title compound, C15H15NOS, whose mol-ecular structure matches the asymmetric unit. The mol-ecule is not planar, the dihedral angle between the aromatic and the thio-phene rings being 11.4 (2)°. In the crystal, mol-ecules are linked by C-H⋯O and weak C-H⋯S inter-actions along [100], forming R2(2) (8) rings, and by weak C-H⋯O inter-actions along [010], forming chains with a C(6) graph-set motif...
April 1, 2017: Acta Crystallographica. Section E, Crystallographic Communications
https://www.readbyqxmd.com/read/28435577/intra-articular-localized-haemangioma-of-the-knee-mimicking-localized-pigmented-villonodular-synovitis-a-case-report
#6
G K Goki-Kamei, N M Norimasa-Matsubara, T T Teruyasu-Tanaka, K N Koji-Natsu, T S Toshihiro-Sugioka
Intra-articular synovial haemangioma of the knee is a benign tumour. However, diagnostic delay leads to degenerative changes in the cartilage and osteoarthritis due to recurrent haemarthrosis. Therefore, treatment should be performed immediately. We report the case of a localized synovial haemangioma arising from the medial plica in a 38-year old female presenting with pain and restricted range of motion in the right knee joint. Initially, we diagnosed this case as a localized pigmented villonodular synovitis (LPVS) based on MRI and arthroscopic findings and performed only arthroscopic en bloc excision of the mass and synovectomy around the mass for diagnostic confirmation...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435450/exome-sequencing-of-oral-squamous-cell-carcinoma-reveals-molecular-subgroups-and-novel-therapeutic-opportunities
#7
Shih-Chi Su, Chiao-Wen Lin, Yu-Fan Liu, Wen-Lang Fan, Mu-Kuan Chen, Chun-Ping Yu, Wei-En Yang, Chun-Wen Su, Chun-Yi Chuang, Wen-Hsiung Li, Wen-Hung Chung, Shun-Fa Yang
Oral squamous cell carcinoma (OSCC), an epithelial malignancy affecting a variety of subsites in the oral cavity, is prevalent in Asia. The survival rate of OSCC patients has not improved over the past decades due to its heterogeneous etiology, genetic aberrations, and treatment outcomes. Improvement in therapeutic strategies and tailored treatment options is an unmet need. To unveil the mutational spectrum, whole-exome sequencing of 120 OSCC from male individuals in Taiwan was conducted. Analyzing the contributions of the five mutational signatures extracted from the dataset of somatic variations identified four groups of tumors that were significantly associated with demographic and clinical features...
2017: Theranostics
https://www.readbyqxmd.com/read/28434863/spatiotemporally-controlled-mechanical-cues-drive-progenitor-mesenchymal-to-epithelial-transition-enabling-proper-heart-formation-and-function
#8
Timothy R Jackson, Hye Young Kim, Uma L Balakrishnan, Carsten Stuckenholz, Lance A Davidson
During early cardiogenesis, bilateral fields of mesenchymal heart progenitor cells (HPCs) move from the anterior lateral plate mesoderm to the ventral midline, undergoing a mesenchymal-to-epithelial transition (MET) en route to forming a single epithelial sheet. Through tracking of tissue-level deformations in the heart-forming region (HFR) as well as movement trajectories and traction generation of individual HPCs, we find that the onset of MET correlates with a peak in mechanical stress within the HFR and changes in HPC migratory behaviors...
April 17, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28434624/obesity-and-kidney-disease-hidden-consequences-of-the-epidemic
#9
Csaba P Kovesdy, Susan Furth, Carmine Zoccali
No abstract text is available yet for this article.
April 20, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28434546/surgical-strategy-toward-biventricular-repair-for-severe-ebstein-anomaly-in-neonates-and-infancy
#10
Shu-Chien Huang, En-Ting Wu, Shyh-Jye Chen, Chi-Hsiang Huang, Jin-Chung Shih, Hen-Wen Chou, Chung-I Chang, Ing-Sh Chiu, Yih-Sharng Chen
BACKGROUND: Neonates with severe forms of Ebstein anomaly present a surgical challenge, and the Starnes operation as single ventricle palliation is highly advocated. Cone reconstruction for tricuspid valvuloplasty (TVP) has become a widely accepted technique, although very few cases of TVP have been reported in neonates. This report describes a surgical strategy for neonatal Ebstein anomaly, with an aim toward biventricular repair. METHODS: Since 2007, 7 neonates or young infants with severe Ebstein anomalies have received TVP at the National Taiwan University Hospital, Taipei, Taiwan...
April 20, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28434205/molecular-systematics-reveals-increased-diversity-within-the-south-african-laurencia-complex-rhodomelaceae-rhodophyta
#11
Caitlynne Francis, John J Bolton, Lydiane Mattio, Tshifhiwa G Mandiwana-Neudani, Robert J Anderson
Previous publications list ten species in the Laurencia complex from South Africa with all ascribed to the genus Laurencia sensu stricto. However, the diversity of the complex in South Africa has not yet been reassessed following the numerous recent taxonomic changes. The present study investigated the phylogenetic relationships and taxonomy of this group in South Africa using recent collections. Methods included a molecular phylogenetic analysis of plastid rbcL gene sequences (a total of 146; including eleven outgroup taxa) using Bayesian Inference, and the examination of morphological and anatomical characters, including the number of corps en cerise when present...
April 23, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/28434196/role-of-gut-microbiota-bile-acids-and-their-crosstalk-in-the-effects-of-bariatric-surgery-on-obesity-and-type-2-diabetes
#12
Haijun Liu, Cheng Hu, Xueli Zhang, Weiping Jia
Type 2 diabetes mellitus is becoming increasingly prevalent worldwide and has become one of the greatest threats to global health. Bariatric surgery was initially designed to achieve weight loss and subsequently was noted to induce improvements or remission of type 2 diabetes. Currently, these bariatric operations such as Roux-en-Y gastric bypass (RYGB) and sleeve gastrectomy (SG) are the most effective procedures for the treatment of obesity and type 2 diabetes mellitus worldwide. However, the specific mechanism mediating the beneficial effects of metabolic surgery has remained largely unknown...
April 23, 2017: Journal of Diabetes Investigation
https://www.readbyqxmd.com/read/28434026/erratum-to-transposon-insertion-resulted-in-the-silencing-of-wx-b1n-in-chinese-wheat-landraces
#13
Ling-Ling Zhang, Hu Chen, Mi Luo, Xiao-Wei Zhang, Mei Deng, Jian Ma, Peng-Fei Qi, Ji-Rui Wang, Guo-Yue Chen, Ya-Xi Liu, Zhi-En Pu, Wei Li, Xiu-Jin Lan, Yu-Ming Wei, You-Liang Zheng, Qian-Tao Jiang
No abstract text is available yet for this article.
April 22, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28433873/ph-dependent-synthesis-of-two-isomeric-dinuclear-cerium-ii-complexes-structures-dna-interactions-cytotoxic-activity-and-apoptotic-study
#14
En-Jun Gao, Jun-Qi Su, Hai-Tao Jin, Si-Jia Liu, Fu-Chen Zhao, Yang Meng, Xiao-Yu Ma, Jing Ge, Ya-Guang Sun, Wanzhong Zhang, Ming-Chang Zhu
Two isomeric dinuclear Cerium(II) complexes 1 and 2, formulated as Ce2(phen)2(NO3)2(L)4 [L=phenylacetic acid, phen=1,10-phenanthroline] was synthesized under solvothermal conditions at different pH values. The two complexes were characterized by elemental analysis, IR and single crystal X-ray diffraction. Complexes 1 and 2 were studied the binding with DNA and against cytotoxic activity. Fluorescence analysis indicated that the two complexes can bind to DNA. The changes with different gradient concentration of DNA added into the complexes in absorption spectra show a strongπ-stacking interaction between the complexes and DNA base pairs...
April 11, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28433850/surgical-resection-and-histopathological-analysis-of-a-thrombosed-giant-fusiform-mca-aneurysm-after-initial-treatment-with-a-flow-diversion-construct
#15
Jayson Sack, Vincent Cheung, Deirdre Amaro, Arvin R Wali, David R Santiago-Dieppa, J Scott Pannell, Alexander A Khalessi
BACKGROUND: We describe the histopathology of an un-ruptured, giant calcified left MCA fusiform aneurysm initially treated with endovascular flow diversion. The flow diversion construct underwent post-operative in-stent thrombosis, necessitating surgical resection of the aneurysm to eliminate mass effect. METHODS: A 75-year-old woman with a known left MCA aneurysm presented to the Emergency Department with moderate right hemibody weakness. Due to the clinical and radiographic progression of the aneurysm, the patient was offered treatment...
April 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28433725/clinical-characteristics-and-surgical-treatment-of-spinal-paraganglioma-a-case-series-of-18-patients
#16
Mengchen Yin, Quan Huan, Zhengwang Sun, Shaohui He, Ye Xia, Wen Mo, Junming Ma, Jianru Xiao
BACKGROUND AND OBJECTIVES: Paraganglioma rarely develops in the spine. With few cases reported, little knowledge about this disease was known. The objective of this study is to illustrate the clinical features, imaging manifestations, pathological appearances and long-term outcomes of the consecutive surgeries by literature review. METHODS: The clinical and follow-up data of 18 patients who were diagnosed of spinal paraganglioma and treated with surgeries in our hospitals from 2003 to 2014 were retrospectively analyzed...
March 30, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28433709/pulmonary-pathobiology-induced-by-zinc-oxide-nanoparticles-in-mice-a-24-hour-and-28-day-follow-up-study
#17
Hsiao-Chi Chuang, Kai-Jen Chuang, Jen-Kun Chen, His-En Hua, Yen-Ling Shen, Wei-Neng Liao, Chii-Hong Lee, Chih-Hong Pan, Kuan-Yuan Chen, Kang-Yun Lee, Ta-Chih Hsiao, Tsun-Jen Cheng
Inhaled zinc oxide nanoparticles (ZnONPs) have high deposition rates in the alveolar region of the lungs; however, the adverse health effects of ZnONPs on the respiratory system are unclear. Herein, pathobiological responses of the respiratory system of mice that received intratracheal administration of ZnONPs were investigated by a combination of molecular and imaging (SPECT and CT) approaches. Also, normal BEAS-2B and adenocarcinoma A549 cells were used to confirm the results in mice. First, female BALB/c mice were administrated a series of doses of 20-nm ZnONPs and were compared to the phosphate-buffered saline control for 24-h and 28-day follow-up observations...
April 19, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28433552/roscovitine-attenuates-intimal-hyperplasia-via-inhibiting-nf-%C3%AE%C2%BAb-and-stat3-activation-induced-by-tnf-%C3%AE-in-vascular-smooth-muscle-cells
#18
Ming He, Chao Wang, Jia-Huan Sun, Yu Liu, Hong Wang, Jing-Shan Zhao, Yun-Feng Li, Hong Chang, Jian-Ming Hou, Jun-Na Song, Ai-Ying Li, En-Sheng Ji
Roscovitine is a selective CDK inhibitor originally designed as anti-cancer agent, which has also been shown to inhibit proliferation in vascular smooth muscle cells (VSMCs). However, its effect on vascular remodeling and its mechanism of action remain unknown. In our study, we created a new intimal hyperplasia model in male Sprague-Dawley rats by trypsin digestion method, which cause to vascular injury as well as the model of rat carotid balloon angioplasty. Roscovitine administration led to a significant reduction in neointimal formation and VSMCs proliferation after injury in rats...
April 19, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28433465/dumping-symptoms-is-triggered-by-fat-as-well-as-carbohydrates-in-patients-operated-with-roux-en-y-gastric-bypass
#19
Anna Laurenius, Malin Werling, Carel W le Roux, Lars Fändriks, Torsten Olbers
BACKGROUND: Dumping syndrome after Roux-en-Y gastric bypass (RYGB) is traditionally associated with the consumption of refined carbohydrates, but the role of dietary fat is unclear. OBJECTIVES: This study compares symptoms after consumption of a carbohydrate-rich or fat-rich beverage to determine perceived symptoms, glycemic control, and pulse rate. SETTING: University hospital. METHODS: We assessed perceived symptoms (Sigstad's Dumping Index) and glycemic control (P-glucose and S-insulin) as well as autonomic nervous system activity (reflected by arterial pulse rate) after a standardized liquid meal test (440 kcal/300 mL carbohydrates [CARB] or fat [FAT]) in a randomized crossover blinded setting...
March 1, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28433464/electronic-synoptic-reporting-assessing-the-completeness-of-synoptic-and-narrative-reports-for-roux-en-y-gastric-bypass
#20
Ashley Vergis, Shannon E Stogryn, Michael J Mullan, Krista Hardy
BACKGROUND: Operative reporting is the foundation of surgical communication. The quality indicators (QIs) contained in these reports can be used to document the performance of processes that affect patient care and may afford quality assurance with improvement in healthcare. OBJECTIVES: We assessed the degree to which the electronic synoptic report (SR) documents the operative QIs compared with narrative reports (NR) for Roux-en-Y gastric bypass (RYGB). The time to report availability on patient chart was also identified as a secondary measure...
March 7, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
keyword
keyword
51113
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"