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Intravenous paracetamol

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https://www.readbyqxmd.com/read/28828381/paracetamol-in-patent-ductus-arteriosus-treatment-efficacious-and-safe
#1
REVIEW
Flaminia Bardanzellu, Paola Neroni, Angelica Dessì, Vassilios Fanos
In preterm infants, failure or delay in spontaneous closure of Ductus Arteriosus (DA), resulting in the condition of Patent Ductus Arteriosus (PDA), represents a significant issue. A prolonged situation of PDA can be associated with several short- and long-term complications. Despite years of researches and clinical experience on PDA management, unresolved questions about the treatment and heterogeneity of clinical practices in different centers still remain, in particular regarding timing and modality of intervention...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28812394/the-use-of-sustained-low-efficiency-dialysis-sled-in-massive-paracetamol-overdose
#2
Anselm Wong, Roger L K Tong, Liam Ryan, Tim Crozier, Andis Graudins
CONTEXT: Massive paracetamol ingestion causing mitochondrial dysfunction is uncommon. Use of sustained low-efficiency dialysis (SLED) to improve acidaemia and enhance paracetamol elimination has not been previously described. CASE DETAILS: A 44-year-old male presented to the emergency department 2.5 hours post overdose of 200 g (2.5 g/kg) of paracetamol. Examination revealed a BP 85/60 mmHg, pulse 112 bpm, temperature 33.9 °C and blood glucose of 13...
August 16, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28761375/continuous-transversus-abdominis-plane-block-vs-intermittent-bolus-for-analgesia-after-abdominal-surgery-a-randomized-trial
#3
Vasanth Rao Kadam, Roelof M Van Wijk, John L Moran, Shantan Ganesh, A Kumar, Rajesh Sethi, Patricia Williams
BACKGROUND: Continuous and intermittent bolus techniques of transversus abdominis plane (TAP) blocks have been used for analgesia after abdominal surgery. Although both are effective, there are no studies comparing them. The aim of this study is to compare analgesia and cost-effectiveness between these groups. METHODS: After obtaining ethical approval, 20 American Society of Anesthesiologists ASA grade I to III patients undergoing elective abdominal surgery were recruited with 10 patients allocated to each arm...
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/28756679/accuracy-of-the-paracetamol-aminotransferase-product-to-predict-hepatotoxicity-in-paracetamol-overdose-treated-with-a-2-bag-acetylcysteine-regimen
#4
Anselm Wong, Marco L A Sivilotti, Naren Gunja, Richard McNulty, Andis Graudins
INTRODUCTION: Paracetamol concentration is a highly accurate risk predictor for hepatotoxicity following overdose with known time of ingestion. However, the paracetamol-aminotransferase multiplication product can be used as a risk predictor independent of timing or ingestion type. Validated in patients treated with the traditional, "three-bag" intravenous acetylcysteine regimen, we evaluated the accuracy of the multiplication product in paracetamol overdose treated with a two-bag acetylcysteine regimen...
July 31, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28745155/single-dose-intravenous-paracetamol-or-intravenous-propacetamol-for-postoperative-pain
#5
Amanda Stott
statement The mission of the Cochrane Nursing Care Field (CNCF) is to improve health outcomes through increasing the use of the Cochrane Library and supporting Cochrane's role by providing an evidence base for nurses and healthcare professionals who deliver, lead or research nursing care. The CNCF produces Cochrane Corner columns, summaries of recent nursing-care-relevant Cochrane Reviews that are regularly published in collaborating nursing-related journals. Information on the processes CNCF has developed can be accessed at: cncf...
July 26, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28707454/interventions-for-postoperative-pain-in-children-an-overview-of-systematic-reviews
#6
REVIEW
Krste Boric, Svjetlana Dosenovic, Antonia Jelicic Kadic, Marijan Batinic, Marija Cavar, Marjan Urlic, Nikolina Markovina, Livia Puljak
The aim of this study was to conduct an overview of systematic reviews that summarizes the results about efficacy and safety from randomized controlled trials involving the various strategies used for postoperative pain management in children. We searched the Cochrane Database of Systematic Reviews, CINAHL, Database of Reviews of Effect, Embase, MEDLINE, and PsycINFO from the earliest date to January 24, 2016. This overview included 45 systematic reviews that evaluated interventions for postoperative pain in children...
September 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28681267/intravenous-paracetamol-vs-ibuprofen-in-renal-colic-a-randomised-double-blind-controlled-clinical-trial
#7
E Cenker, M Serinken, E Uyanık
Pain management is one of the essentials of emergency care. Renal colic secondary to urinary stone disease forms one of the most intense pain types. The present study aimed to compare the effect of intravenous ibuprofen to paracetamol in ceasing renal colic. This randomised double-blind study was composed of two intervention arms, intravenous paracetamol and intravenous ibuprofen. Study subjects were randomised to receive a single dose of either paracetamol, 1 g in 100 ml normal saline, or ibuprofen (800 mg in 100 ml normal saline) in a blinded fashion...
July 5, 2017: Urolithiasis
https://www.readbyqxmd.com/read/28680512/the-presenting-and-prescribing-patterns-of-migraine-in-an-australian-emergency-department-a-descriptive-exploratory-study
#8
Emily Shao, James Hughes, Rob Eley
BACKGROUND: Migraine is a common neurological condition that frequently presents to the emergency department (ED). Many medications are available to treat migraine. This study aims to characterize the demographics of patients who present to a large metropolitan ED with migraine, and to identify the medications used in treating this condition. METHODS: This study is a retrospective database interrogation of clinical records, used to collect quantitative data on patient demographics and medication prescriptions in the ED...
2017: World Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28667547/transversus-abdominis-plane-tap-block-versus-thoracic-epidural-analgesia-tea-in-laparoscopic-colon-surgery-in-the-eras-program
#9
Basilio Pirrera, Vincenzo Alagna, Andrea Lucchi, Pierluigi Berti, Carlo Gabbianelli, Giacomo Martorelli, Lorella Mozzoni, Federico Ruggeri, Alessandro Ingardia, Giuseppe Nardi, Gianluca Garulli
AIM: The enhanced recovery after surgery (ERAS) pathway and laparoscopic approach had been proven beneficial for patients and should now be considered as a standard of care in colorectal surgery. Multimodal analgesia is the gold standard in the ERAS program with the use of thoracic epidural analgesia (TEA). Few data are available on Transversus abdominis plane (TAP) blocks in laparoscopic colorectal surgery and ERAS pathway. The aim of this study is to evaluate the efficacy of TAP block compared to TEA in the management of postoperative pain and the impact on the recurrence of postoperative nausea, vomiting and ileus in laparoscopic colorectal surgery in the ERAS program...
July 1, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28663644/comparison-of-intravenous-infusion-of-tramadol-alone-with-combination-of-tramadol-and-paracetamol-for-postoperative-pain-after-major-abdominal-surgery-in-children
#10
Shayesta Ali, Khalid Sofi, Abdul Qayoom Dar
BACKGROUND: Pain is a common complaint after surgery and seems to be difficult to manage in children because of fear of complications of pain treatment or misconception that infants and small children do not feel pain at all or feel less pain. A survey reported that 40% of pediatric surgical patients experienced moderate or severe postoperative pain and that more than 75% had insufficient analgesia. Our study was carried to provide continuous infusion of intravenous (i.v.) tramadol alone using a dedicated infusion device Graseby 2100 syringe pump and compared it to a combination of i...
April 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28618198/effect-of-intravenous-paracetamol-as-pre-emptive-compared-to-preventive-analgesia-in-a-pediatric-dental-setting-a-prospective-randomized-study
#11
Johny Kharouba, Nasir Hawash, Benjamin Peretz, Sigalit Blumer, Yara Srour, Marry Nassar, Mulham Sabbah, Anan Safadi, Alexey Khorev, Mostafa Somri
BACKGROUND: Efficacy of pre-emptive analgesia compared to preventive regimen, managing postoperative pain is still controversial. AIM: Evaluating the efficacy of intravenous (IV) paracetamol as pre-emptive analgesia compared to preventive post-treatment administration in pediatric dental setting. DESIGN: In a prospective trial, 60 noncooperative children of ASA I, II aged 3-10 years who underwent dental rehabilitation under general anesthesia were randomly divided into two groups...
June 15, 2017: International Journal of Paediatric Dentistry
https://www.readbyqxmd.com/read/28601802/intravenous-paracetamol-or-intravenous-propacetamol-can-provide-effective-postoperative-analgesia-for-some-patients
#12
REVIEW
Patricia O'Malley
No abstract text is available yet for this article.
June 10, 2017: Evidence-based Nursing
https://www.readbyqxmd.com/read/28586638/efficacy-of-codeine-when-added-to-paracetamol-acetaminophen-and-ibuprofen-for-relief-of-postoperative-pain-after-surgical-removal-of-impacted-third-molars-a-double-blinded-randomized-control-trial
#13
Adrian D Best, R K De Silva, W M Thomson, Darryl C Tong, Claire M Cameron, Harsha L De Silva
PURPOSE: The use of opioids in combination with nonopioids is common practice for acute pain management after third molar surgery. One such combination is paracetamol, ibuprofen, and codeine. The authors assessed the efficacy of codeine when added to a regimen of paracetamol and ibuprofen for pain relief after third molar surgery. MATERIALS AND METHODS: This study was a randomized, double-blinded, placebo-controlled trial conducted in patients undergoing the surgical removal of at least 1 impacted mandibular third molar requiring bone removal...
May 15, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28585750/effects-of-intraoperative-liberal-fluid-therapy-on-postoperative-nausea-and-vomiting-in-children-a-randomized-controlled-trial
#14
Vighnesh Ashok, Indu Bala, Neerja Bharti, Divya Jain, Ram Samujh
BACKGROUND: Postoperative nausea and vomiting (PONV) is one of the most distressing complications following surgery. Supplemental perioperative fluid therapy might be an effective strategy to reduce PONV in children. OBJECTIVES: The study was conducted to evaluate the effects of intraoperative liberal fluid therapy with crystalloids on PONV in children. METHODS: In this randomized trial, a total of 150 children of 3-7 years undergoing lower abdominal and penile surgery under general anesthesia were randomly assigned into two groups...
June 6, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28576901/anankle-trial-study-protocol-a-randomised-trial-comparing-pain-profiles-after-peripheral-nerve-block-or-spinal-anaesthesia-for-ankle-fracture-surgery
#15
Rune Sort, Stig Brorson, Ismail Gögenur, Ann Merete Møller
INTRODUCTION: Ankle fracture surgery is a common procedure, but the influence of anaesthesia choice on postoperative pain and quality of recovery is poorly understood. Some authors suggest a benefit of peripheral nerve block (PNB) in elective procedures, but the different pain profile following acute fracture surgery and the rebound pain on cessation of the PNB both remain unexplored. We present an ongoing randomised study aiming to compare primary PNB anaesthesia with spinal anaesthesia for ankle fracture surgery regarding postoperative pain profiles and quality of recovery...
June 2, 2017: BMJ Open
https://www.readbyqxmd.com/read/28558384/randomized-controlled-trial-comparing-different-single-doses-of-intravenous-paracetamol-for-placement-of-peripherally-inserted-central-catheters-in-preterm-infants
#16
Daniella W E Roofthooft, Sinno H P Simons, Richard A van Lingen, Dick Tibboel, John N van den Anker, Irwin K H Reiss, Monique van Dijk
BACKGROUND: The availability of a safe and effective pharmacological therapy to reduce procedural pain in preterm infants is limited. The effective analgesic single dose of intravenous paracetamol in preterm infants is unknown. Comparative studies on efficacy of different paracetamol doses in preterm infants are lacking. OBJECTIVES: To determine the analgesic effects of different single intravenous paracetamol doses on pain from peripherally inserted central catheter (PICC) placement in preterm infants...
2017: Neonatology
https://www.readbyqxmd.com/read/28550147/what-is-the-dose-of-intravenous-paracetamol-for-pain-relief-in-neonates
#17
EDITORIAL
Paola Mian, Catherijne Aj Knibbe, Dick Tibboel, Karel Allegaert
No abstract text is available yet for this article.
July 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28492168/accidental-intravenous-administration-of-paracetamol-syrup-in-a-child
#18
D El Mazloum, A Boner, A Pietrobelli
OBJECTIVE AND IMPORTANCE: Medication administration errors occur frequently in clinical practice. CLINICAL PRESENTATION: An 18-month-old child presented with vomiting and diarrhea. Due to a rise in temperature, paracetamol syrup was prescribed, but a nurse inadvertently administered the drug IV through the peripheral venous access. INTERVENTION: The child was referred to the pediatric intensive care unit where his clinical condition improved and the risk of peripheral venous and pulmonary embolism was excluded...
December 2016: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28405033/post-caesarean-analgesia-what-is-new
#19
REVIEW
Sukhyanti Kerai, Kirti Nath Saxena, Bharti Taneja
Adequate post-operative analgesia after caesarean section (CS) is vital as it impacts the distinct surgical recovery requirements of the parturient. Although newer analgesic modalities and drugs for post-caesarean analgesia have been introduced over the recent years, review of the literature suggests suggests that we are far from achieving the goals of optimum post-operative analgesia. We conducted a systematic review of recent advances in modalities for post-caesarean analgesia. After systematic search and quality assessment of studies, we included a total of 51 randomised controlled trials that evaluated the role of opioids, transversus abdominis plane (TAP) block, wound infiltration/infusion, ketamine, gabapentin and ilioinguinal-iliohypogastric nerve block (II-IH NB) for post-caesarean analgesia...
March 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28328698/reduced-sufentanil-doses-are-effective-for-postoperative-analgesia-after-ductal-closure-in-extremely-premature-infants-a-10-years-retrospective-cohort-study
#20
Yohan Soreze, Etienne Audureau, Fabrice Decobert, Olivier Jaby, Sabine Blary, Claude Danan, Xavier Durrmeyer
OBJECTIVES: The objective of the study was to assess the efficacy of reduced sufentanil doses for postoperative analgesia following surgical ductal closure in extremely premature infants. METHODS: This was a retrospective, single-center, cohort study comparing 2 sufentanil dosing regimens used between 2001 and 2010 and included all infants born at <28 weeks of gestation with surgical ductal closure. Sufentanil doses were reduced in 2007 as a standard of care...
March 21, 2017: Clinical Journal of Pain
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