Joakim Steiness, Daniel Hägi-Pedersen, Troels Haxholdt Lunn, Søren Overgaard, Stig Brorson, Ben Kristian Graungaard, Martin Lindberg-Larsen, Claus Varnum, Lars Hyldborg Lundstrøm, Torben Beck, Michael Skettrup, Niels Anker Pedersen, Manuel Josef Bieder, Adam Gregers von Cappeln, Lina Pleckaitiene, Peter Lindholm, Syed Shaheer Haider Bukhari, Cecilie Bauer Derby, Maria Gantzel Nielsen, Oskar Wilborg Exsteen, Louise Ørts Vinstrup, Kasper Højgaard Thybo, Kasper Smidt Gasbjerg, Anders Kehlet Nørskov, Janus Christian Jakobsen, Ole Mathiesen
BACKGROUND: Multimodal postoperative analgesia following total hip arthroplasty is recommended, but the optimal combination of drugs remains uncertain. The aim of the RECIPE trial was to investigate the relative benefit and harm of the different combinations of paracetamol, ibuprofen, and the analgesic adjuvant dexamethasone for treatment of postoperative pain following total hip arthroplasty. METHODS: The RECIPE trial was a randomised, blinded, placebo-controlled trial conducted at nine Danish hospitals...
March 5, 2024: Lancet Rheumatology