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https://www.readbyqxmd.com/read/28528169/editorial-overview-environmental-biotechnology
#1
EDITORIAL
Jan Roelof van der Meer, Man Bock Gu
No abstract text is available yet for this article.
May 17, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28528111/protection-of-%C3%AE-carotene-from-chemical-degradation-in-emulsion-based-delivery-systems-using-antioxidant-interfacial-complexes-catechin-egg-white-protein-conjugates
#2
Luping Gu, Yujie Su, Mengqi Zhang, Cuihua Chang, Junhua Li, David Julian McClements, Yanjun Yang
The aim of the present study was to fabricate catechin-egg white protein (CT-EWP) conjugates as novel food-grade antioxidant emulsifiers designed to improve the physicochemical stability of β-carotene (BC) emulsions. CT-EWP conjugates were synthesized using free radical grafting, and the formation of conjugates was confirmed by electrophoresis and liquid chromatography-mass spectrometry. The physicochemical stability of BC emulsions was characterized by measuring alterations in particle size, ζ-potential and BC retention...
June 2017: Food Research International
https://www.readbyqxmd.com/read/28527757/comparative-analysis-of-peri-operative-complications-between-a-multicenter-prospective-cervical-deformity-database-and-the-nationwide-inpatient-sample-database
#3
Peter G Passias, Samantha R Horn, Cyrus M Jalai, Gregory Poorman, Olivia J Bono, Subaraman Ramchandran, Justin S Smith, Justin K Scheer, Daniel M Sciubba, D Kojo Hamilton, Gregory Mundis, Cheongeun Oh, Eric O Klineberg, Virginie Lafage, Christopher I Shaffrey, Christopher P Ames
BACKGROUND CONTEXT: Complication rates for adult cervical deformity are poorly characterized given the complexity and heterogeneity of cases. PURPOSE: To compare peri-operative complication rates following adult cervical deformity corrective surgery between a prospective multi-center database for cervical deformity patients (PCD) and Nationwide Inpatient Sample (NIS). STUDY DESIGN/SETTING: Retrospective review of prospective databases. PATIENT SAMPLE: 11,501 adult cervical deformity patients (11,379 patients from NIS and 122 patients from PCD database)...
May 17, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28527743/distribution-and-sources-of-organic-carbon-nitrogen-and-their-isotopes-in-surface-sediments-from-the-largest-mariculture-zone-of-the-eastern-guangdong-coast-south-china
#4
Yang-Guang Gu, Jun Ouyang, Jia-Jia Ning, Zeng-Huan Wang
China is the world's largest mariculture producer. However, there is limited detailed information on organic matter distribution generated by mariculture in China. This study assessed the total organic carbon (TOC), total nitrogen (TN), and isotopic composition (δ(13)C and δ(15)N) in surface sediments from Zhelin Bay in South China. TOC, TN, δ(13)C and δ(15)N ranged from 0.46-1.23%, 0.08-0.20%, -22.07 to -21.13‰ and 5.28-7.14‰, respectively, and followed similar spatial patterns. The C/N ratio coupled with isotopic composition (δ(13)C and δ(15)N), indicates that the TOC originated from both terrestrial and marine sources...
May 17, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28527433/partial-hydrodynamic-representation-of-quantum-molecular-dynamics
#5
Bing Gu, Ignacio Franco
A hybrid method is proposed to propagate system-bath quantum dynamics that use both basis functions and coupled quantum trajectories. In it, the bath is represented with an ensemble of Bohmian trajectories while the system degrees of freedom are accounted through reduced density matrices. By retaining the Hilbert space structure for the system, the method is able to capture interference processes that are challenging to describe in Bohmian dynamics due to singularities that these processes introduce in the quantum potential...
May 21, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28527428/physicochemical-and-biological-interactions-between-cerium-oxide-nanoparticles-and-a-1-8-naphthalimide-derivative
#6
Gerardo Pulido-Reyes, Esperanza Martín, J L Gu Coronado, Francisco Leganes, Roberto Rosal, Francisca Fernández-Piñas
Cerium (Ce) oxide nanoparticles (CNPs) have attracted attention due to their high bioactivity and unique redox-chemistry. The oxygen vacancies at the surface of the nanoparticle explain the autocatalytic properties of CNPs in which the Ce(3+) atoms occupy the center of the oxygen vacancies surrounded by Ce(4+) atoms. Until now, CNPs have been associated with organic molecules at the synthesis stage to extend their applications or improve their stability. However, there is a lack of information regarding the post-synthesis interaction of CNPs and organic molecules that could enhance or induce new properties...
May 10, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28527358/improving-the-pharmacokinetics-and-tissue-distribution-of-pyrinezolid-by-self-assembled-polymeric-micelles
#7
Haiyue Long, Xiaoling Li, Zitai Sang, Lan Mei, Tao Yang, Zicheng Li, Liangxue Zhou, Yu Zheng, Gu He, Gang Guo, Zhenling Wang, Yong Deng, Youfu Luo
Antibiotic-resistance by bacteria is a growing global concern within the healthcare field, and it has provided an impetus for continued antimicrobial development. Pyrinezolid (PZ), a novel oxazolidinone compound, can effectively inhibit most gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). Though PZ is a promising antimicrobial candidate, the druggability of PZ is limited by its poor water solubility. Therefore, the amphipathic mPEG-PLLA copolymer was used to prepare the pyrinezolid micelles (PZ-M)...
May 8, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28527111/human-placenta-derived-mesenchymal-stem-cells-loaded-on-linear-ordered-collagen-scaffold-improves-functional-recovery-after-completely-transected-spinal-cord-injury-in-canine
#8
Sufang Han, Zhifeng Xiao, Xing Li, Huan Zhao, Bin Wang, Zhixue Qiu, Zhi Li, Xin Mei, Bai Xu, Caixia Fan, Bing Chen, Jin Han, Yanzheng Gu, Huilin Yang, Qin Shi, Jianwu Dai
Traumatic spinal cord injury (SCI) is a major challenge in the clinic. In this study, we sought to examine the synergistic effects of linear ordered collagen scaffold (LOCS) and human placenta-derived mesenchymal stem cells (hPMSCs) when transplanted into completely transected beagle dogs. After 36 weeks observation, we found that LOCS+hPMSCs implants promoted better hindlimb locomotor recovery than was observed in the non-treatment (control) group and LOCS group. Histological analysis showed that the regenerated tissue after treatment was well integrated with the host tissue, and dramatically reduced the volume of cystic and chondroitin sulfate proteoglycans (CSPGs) expression...
May 16, 2017: Science China. Life Sciences
https://www.readbyqxmd.com/read/28526382/quality-of-diet-and-level-of-physical-performance-related-to-inflammatory-markers-in-community-dwelling-frail-elderly-people
#9
Do-Yeon Kim, Chang-O Kim, Hyunjung Lim
OBJECTIVE: The aim of this study was to assess whether diet quality and functional status were associated with serum levels of interleukin (IL)-6 and tumor necrosis factor (TNF)-α in frail, elderly, community-dwelling individuals. METHODS: Seventy-eight frail, elderly individuals (age ≥65 y, usual gait speed <0.6 m/s and Mini Nutritional Assessment <24) participated in this cross-sectional study from the National Home Healthcare Services in Gangbuk-gu, Seoul, South Korea...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28526339/magnesium-isoglycyrrhizinate-blocks-fructose-induced-hepatic-nf-%C3%AE%C2%BAb-nlrp3-inflammasome-activation-and-lipid-metabolism-disorder
#10
Xiao-Juan Zhao, Yan-Zi Yang, Yan-Jing Zheng, Shan-Chun Wang, Hong-Mei Gu, Ying Pan, Shui-Juan Wang, Hong-Jiang Xu, Ling-Dong Kong
Magnesium isoglycyrrhizinate as a hepatoprotective agent possesses immune modulation and anti-inflammation, and treats liver diseases. But its effects on immunological-inflammatory and metabolic profiles for metabolic syndrome with liver injury and underlying potential mechanisms are not fully understood. In this study, magnesium isoglycyrrhizinate alleviated liver inflammation and lipid accumulation in fructose-fed rats with metabolic syndrome. It also suppressed hepatic inflammatory signaling activation by reducing protein levels of phosphorylation of nuclear factor-kappa B p65 (p-NF-κB p65), inhibitor of nuclear factor kappa-B kinase α/β (p-IKKα/β) and inhibitor of NF-κB α (p-IκBα) as well as nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3), apoptosis-associated speck-like protein (ASC) and Caspase-1 in rats, being consistent with its reduction of interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α) and IL-6 levels...
May 16, 2017: European Journal of Pharmacology
https://www.readbyqxmd.com/read/28526246/impaired-mitophagy-facilitates-mitochondrial-damage-in-danon-disease
#11
Sherin I Hashem, Anne N Murphy, Ajit S Divakaruni, Matthew L Klos, Bradley C Nelson, Emily C Gault, Teisha J Rowland, Cynthia N Perry, Yusu Gu, Nancy D Dalton, William H Bradford, Eric J Devaney, Kirk L Peterson, Kenneth L Jones, Matthew R G Taylor, Ju Chen, Neil C Chi, Eric D Adler
RATIONALE: Lysosomal associated membrane protein type-2 (LAMP-2) is a highly conserved, ubiquitous protein that is critical for autophagic flux. Loss of function mutations in the LAMP-2 gene cause Danon disease, a rare X-linked disorder characterized by developmental delay, skeletal muscle weakness, and severe cardiomyopathy. We previously found that human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) from Danon patients exhibited significant mitochondrial oxidative stress and apoptosis...
May 16, 2017: Journal of Molecular and Cellular Cardiology
https://www.readbyqxmd.com/read/28526199/impacts-of-metal-contamination-and-eutrophication-on-dinoflagellate-cyst-assemblages-along-the-guangdong-coast-of-southern-china
#12
Xinxin Lu, Zhaohui Wang, Xin Guo, Yangguang Gu, Weibiao Liang, Lei Liu
Fifty-one surface sediment samples were collected from eleven sea areas along the Guangdong coast in southern China. Biogenic elements, metals and dinoflagellate cysts were analyzed. Twenty-one cyst taxa in 12 genera were identified. The cyst concentrations ranged between 14 and 250 cysts/g, with an average of 69 cysts/g. The low cyst production was caused by coarse sediments, high sedimentation rates, and high anthropogenic disturbances. Biogenic elements were comparable with those reported. However, the metal concentrations were far lower than the sediment quality guidelines...
May 16, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28526063/targeting-the-cxcr4-pathway-using-a-novel-anti-cxcr4-igg1-antibody-pf-06747143-in-chronic-lymphocytic-leukemia
#13
Manoj K Kashyap, Carlos I Amaya-Chanaga, Deepak Kumar, Brett Simmons, Nanni Huser, Yin Gu, Max Hallin, Kevin Lindquist, Rolla Yafawi, Michael Y Choi, Ale-Ali Amine, Laura Z Rassenti, Cathy Zhang, Shu-Hui Liu, Tod Smeal, Valeria R Fantin, Thomas J Kipps, Flavia Pernasetti, Januario E Castro
BACKGROUND: The CXCR4-CXCL12 axis plays an important role in the chronic lymphocytic leukemia (CLL)-microenvironment interaction. Overexpression of CXCR4 has been reported in different hematological malignancies including CLL. Binding of the pro-survival chemokine CXCL12 with its cognate receptor CXCR4 induces cell migration. CXCL12/CXCR4 signaling axis promotes cell survival and proliferation and may contribute to the tropism of leukemia cells towards lymphoid tissues and bone marrow...
May 19, 2017: Journal of Hematology & Oncology
https://www.readbyqxmd.com/read/28525491/surgery-for-chronic-traumatic-atlantoaxial-dislocation-associated-with-myelopathy
#14
Lingjun Wang, Yong Gu, Liang Chen, Huilin Yang
STUDY DESIGN: A retrospective study. OBJECTIVE: To evaluate the outcomes of myelopathy caused by atlantoaxial dislocation (AAD). SUMMARY OF BACKGROUND DATA: No reports to date have accurately evaluated the results of surgery for delayed myelopathy for patients with chronic AAD. Thus, the appropriate surgical time and methods of decompression and fusion remain a hot debate. MATERIALS AND METHODS: In our study, 18 patients underwent decompression, fixation, and fusion...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525469/safety-and-efficacy-study-of-an-ozone-laser-combined-therapy-using-puncture-needle-in-the-treatment-of-patients-with-cervical-spondylosis
#15
Ke Gu, Yuqiu Yan, Wu Wei, Yan Li, Wenli Liu, Yang Guo, Long Yu
STUDY DESIGN AND METHODS: Fifty-eight patients with cervical spondylosis (CS) were treated with patented technology of ozone laser combined therapy using puncture needle between August 2008 and February 2010. Visual Analogue Scale (VAS) score changes before and 6 months after surgery and MacNab score criteria 6 months after surgery were analyzed. BACKGROUND AND OBJECTIVE: CS normally occurs over the age of 50 and broadly presents as either myelopathy or radiculopathy...
June 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28525388/association-between-body-mass-index-and-presence-of-carotid-plaque-among-low-income-adults-aged-45-years-and-older-a-population-based-cross-sectional-study-in-rural-china
#16
Yongzhong Lou, Bin Li, Lan Su, Zhenhong Mu, Minghao Sun, Hongfei Gu, Jingxian Ni, Yanan Wu, Jun Tu, Jinghua Wang, Xianjia Ning
Carotid plaque is a good surrogate endpoint for assessing arterial atherosclerosis, and atherosclerosis is a reliable predictor of cardiovascular diseases. However, the effect of body mass index on carotid plaque is unknown. Therefore, we aimed to explore the association between body mass index and carotid plaque in a low-income Chinese population. Residents aged ≥45 years and free of stroke and cardiovascular diseases were enrolled and divided into four groups based on body mass index. B-mode ultrasonography was performed to measure carotid plaque...
May 4, 2017: Oncotarget
https://www.readbyqxmd.com/read/28524825/chinese-systemic-lupus-erythematosus-treatment-and-research-group-registry-ix-clinical-features-and-survival-of-childhood-onset-systemic-lupus-erythematosus-in-china
#17
Chan-Yuan Wu, Cai-Feng Li, Qing-Jun Wu, Jian-Hua Xu, Lin-Di Jiang, Lu Gong, Feng-Qi Wu, Jie-Ruo Gu, Jiu-Liang Zhao, Meng-Tao Li, Yan Zhao, Xiao-Feng Zeng
BACKGROUND: Approximately 15-20% cases of systemic lupus erythematosus (SLE) are diagnosed in children. There have been a few studies reporting the epidemiological data of pediatric-onset SLE (cSLE) in China, neither comparing the differences between cSLE and adult-onset SLE (aSLE). The aim of this study was to describe the impact of age of onset on clinical features and survival in cSLE patients in China based on the Chinese SLE Treatment and Research group (CSTAR) database. METHODS: We made a prospective study of 225 cSLE patients (aged Results: The mean age of cSLE patients was 12...
June 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28523218/valence-and-magnitude-ambiguity-in-feedback-processing
#18
Ruolei Gu, Xue Feng, Lucas S Broster, Lu Yuan, Pengfei Xu, Yue-Jia Luo
BACKGROUND: Outcome feedback which indicates behavioral consequences are crucial for reinforcement learning and environmental adaptation. Nevertheless, outcome information in daily life is often totally or partially ambiguous. Studying how people interpret this kind of information would provide important knowledge about the human evaluative system. METHODS: This study concentrates on the neural processing of partially ambiguous feedback, that is, either its valence or magnitude is unknown to participants...
May 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28523030/detection-and-genotyping-of-helicobacter-pylori-among-gastric-ulcer-and-cancer-patients-from-saudi-arabia
#19
Fehmida Bibi, Sana Akhtar Alvi, Sara Ali Sawan, Muhammad Yasir, Ali Sawan, Asif A Jiman-Fatani, Esam I Azhar
BACKGROUND AND OBJECTIVES: Helicobacter pylori (H. pylori) infection is cause of several gastrointestinal diseases in humans. Virulence genes of H. pylori are associated with severity of disease and vary geographically. The aim of present study was to detect H. pylori in formalin-fixed paraffin-embedded (FFPE) tissues and further investigate prevalence of babA2, cagA, iceA1, iceA2, vacA s1/s2 and vacA m1/m2 genotypes in H. pylori from gastric cancer (GC) and gastric ulcer (GU) patients' biopsy samples...
March 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28522951/diagnostic-and-prognostic-value-of-preoperative-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography-for-colorectal-cancer-comparison-with-conventional-computed-tomography
#20
Joo Young Lee, Soon Man Yoon, Jeong Tae Kim, Ki Bae Kim, Mi Jin Kim, Jae Geun Park, Taek-Gu Lee, Sang-Jeon Lee, Sung Soo Koong, Joung-Ho Han, Hee Bok Chae, Seon Mee Park, Sei Jin Youn
BACKGROUND/AIMS: (18)F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) has been used for preoperative staging of colorectal cancer (CRC). However, the diagnostic accuracy of FDG-PET/CT for detection of lymph node or distant metastasis and its prognostic role have not been well established. We therefore evaluated the diagnostic and prognostic value of FDG-PET/CT in comparison with conventional CT for CRC. METHODS: We investigated 220 patients who underwent preoperative FDG-PET/CT and CT, followed by curative surgery for CRC...
April 2017: Intestinal Research
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