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https://www.readbyqxmd.com/read/27906312/widely-tunable-narrow-linewidth-external-cavity-gain-chip-laser-for-spectroscopy-between-1-0-1-1-%C3%A2%C2%B5m
#1
Dong K Shin, Bryce M Henson, Roman I Khakimov, Jacob A Ross, Colin J Dedman, Sean S Hodgman, Kenneth G H Baldwin, Andrew G Truscott
We have developed and characterised a stable, narrow linewidth external-cavity laser (ECL) tunable over 100 nm around 1080 nm, using a single-angled-facet gain chip. We propose the ECL as a low-cost, high-performance alternative to fibre and diode lasers in this wavelength range and demonstrate its capability through the spectroscopy of metastable helium. Within the coarse tuning range, the wavelength can be continuously tuned over 30 pm (7.8 GHz) without mode-hopping and modulated with bandwidths up to 3 kHz (piezo) and 37(3) kHz (current)...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27904968/outcome-measures-of-extracorporeal-life-support-ecls-in-trauma-patients-versus-patients-without-trauma-a-7-year-single-center-retrospective-cohort-study
#2
Christopher Ull, Thomas A Schildhauer, Justus T Strauch, Justyna Swol
This single-center retrospective study included a total of 99 extracorporeal life support (ECLS) cannulated patients assigned to a traumatic extracorporeal life-support cohort (TECLS) or a non-traumatic extracorporeal life-support cohort (NTECLS). Forty-nine TECLS patients and 50 NTECLS patients were compared. The TECLS patients were significantly younger [49.9 years 16.6-86.2 vs. 57.1 (21.4-78.6); p = 0.007] and had lower body mass indices (BMIs) [27.7 kg/m(2) (20-37) vs. 32.5 (19-88.5); p = 0.001] than the NTECLS patients...
November 30, 2016: Journal of Artificial Organs: the Official Journal of the Japanese Society for Artificial Organs
https://www.readbyqxmd.com/read/27902217/microvirga-ossetica-sp-nov-a-new-species-of-rhizobia-isolated-from-root-nodules-of-the-legume-species-vicia-alpestris-steven-originated-from-north-ossetia-region-in-the-caucasus
#3
Vera Safronova, Irina Kuznetsova, Anna Sazanova, Andrey Belimov, Evgeny Andronov, Elizaveta Chirak, Yuri Osledkin, Olga Onishchuk, Oksana Kurchak, Alexander Shaposhnikov, Anne Willems, Igor Tikhonovich
Gram-negative, rod-shaped strains V5/3MT, V5/5K, V5/5M and V5/13 with a medium growth rate were isolated from root nodules of Vicia alpestris plants growing in the North Ossetia region (Caucasus). The sequencing of the partial 16S rDNA gene (rrs) and four housekeeping genes (dnaK, gyrB, recA and rpoB ) showed that the isolates from V. alpestris were most closely related to the species Microvirga zambiemsis (order Rhizobiales, family Methylobacteriaceae) which was described for the single isolate from root nodule of Listia angolensis growing in Zambia...
October 16, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27902207/maripseudobacter-aurantiacus-gen-nov-sp-nov-a-novel-genus-of-the-family-flavobacteriaceae-isolated-from-sedimentation-basin
#4
Can Chen, Yue Su, Tianyi Tao, Geyi Fu, Chongya Zhang, Cong Sun, Xinqi Zhang, Min Wu
A Gram-stain negative, orange-pigmented, aerobic, non-motile and ovoid-to rod-shaped bacterial strain, designated CDA4T, was isolated from a sediment sample collected from the sedimentation basin of a mariculture farm in Zhejiang province of China. The temperature range for growth of strain CDA4T was 15-40°C, with an optimum at 35 °C. The pH range for growth was 6.0-8.5, with an optimum around pH 7.5. NaCl was required for growth at the concentration range of 0.5-5.0 % (w/v) with an optimum at 2.0 % (w/v)...
October 17, 2016: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/27900922/-extracorporeal-life-support-for-legionella-pneumonia
#5
W A C Koekkoek, C Savelkoul, P R Wijnandts, M Platenkamp, D W Donker, D H T Tjan
BACKGROUND: Legionella species cause 5% of all community acquired pneumonias. However, Legionella pneumonia results relatively often in admission to the intensive care unit (ICU). A significant complication is the development of acute respiratory distress syndrome (ARDS). The ICU mortality rate for Legionella pneumonia is > 30% with conventional treatments. CASE DESCRIPTION: A 64-year-old male was admitted to the ICU with respiratory failure due to Legionella pneumonia complicated by ARDS...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27899324/understanding-the-common-themes-and-diverse-roles-of-the-second-extracellular-loop-ecl2-of-the-gpcr-super-family
#6
Michael J Woolley, Alex C Conner
The extracellular loops (ECLs) of G protein-coupled receptors (GPCRs) can bind directly to docked orthosteric or allosteric ligands, they can contain transient contact points for ligand entry into the transmembrane (TM) bundle and they can regulate the activation of the receptor signalling pathways. Of the three ECLs, ECL2 is the largest and most structurally diverse reflecting its functional importance. This has been shown through biochemical techniques and has been supported by the many subsequent crystal structures of GPCRs bound to both agonists and antagonists...
November 26, 2016: Molecular and Cellular Endocrinology
https://www.readbyqxmd.com/read/27884576/extracorporeal-life-support-for-refractory-cardiac-arrest-from-accidental-hypothermia-a-10-year-experience-in-edinburgh
#7
Maziar Khorsandi, Scott Dougherty, Neil Young, Dean Kerslake, Vincenzo Giordano, Robert Lendrum, William Walker, Vipin Zamvar, Ivan Yim, Renzo Pessotto
BACKGROUND: Cardiac arrest caused by accidental hypothermia is a rare phenomenon with a significant mortality rate if untreated. The consensus is that these patients should be rewarmed with extracorporeal life support (ECLS) with the potential for excellent survival and neurologic outcomes. However, given the lack of robust data and clinical trials, the optimal management of such patients remains elusive. OBJECTIVE: In this single-center study, we looked at the outcomes of all adult patients undergoing salvage ECLS for cardiac arrest caused by accidental hypothermia over a 10-year period from June 2006 to June 2016...
November 21, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27883960/a-dual-potential-electrochemiluminescence-ratiometric-sensor-for-sensitive-detection-of-dopamine-based-on-graphene-cdte-quantum-dots-and-self-enhanced-ru-ii-complex
#8
Xiaomin Fu, Xingrong Tan, Ruo Yuan, Shihong Chen
A novel dual-potential ratiometric electrochemiluminescence (ECL) sensor was designed for detecting dopamine (DA) based on graphene-CdTe quantum dots (G-CdTe QDs) as the cathodic emitter and self-enhanced Ru(II) composite (TAEA-Ru) as the anodic emitter. TAEA-Ru was prepared by linking ruthenium(II) tris(2,2'-bipyridyl-4,4'-dicarboxylato) with tris(2-aminoethyl)amine. Firstly, 3-aminopropyltriethoxysilane founctionalized G-CdTe QDs was used as the substrate for capturing target DA via the specific recognition of the diol of DA to the oxyethyl group of APTES...
November 11, 2016: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/27875312/mutational-analysis-of-atypical-chemokine-receptor-3-ackr3-cxcr7-interaction-with-its-chemokine-ligands-cxcl11-and-cxcl12
#9
Besma Benredjem, Mélanie Girard, David Rhainds, Geneviève St-Onge, Nikolaus Heveker
Atypical chemokine receptors do not mediate chemotaxis or G-protein signalling, but they recruit arrestin. They also efficiently scavenge their chemokine ligands, thereby contributing to gradient maintenance and termination. ACKR3, also known as CXCR7, binds and degrades the constitutive chemokine CXCL12, which also binds the canonical receptor CXCR4, and CXCL11, which also binds CXCR3. Here we report comprehensive mutational analysis of the ACKR3 interaction with its chemokine ligands, using 30 substitution mutants...
November 14, 2016: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/27873222/young-children-s-developmental-ecologies-and-kindergarten-readiness
#10
Stefanie Mollborn
Children enter the crucial transition to school with sociodemographic disparities firmly established. Domain-specific research (e.g., on poverty and family structure) has shed light on these disparities, but we need broader operationalizations of children's environments to explain them. Building on existing theory, this study articulates the concept of developmental ecology-those interrelated features of a child's proximal environment that shape development and health. Developmental ecology links structural and demographic factors with interactional, psychological, and genetic factors...
December 2016: Demography
https://www.readbyqxmd.com/read/27873045/the-interplay-between-early-father-involvement-and-neonatal-medical-risk-in-the-prediction-of-infant-neurodevelopment
#11
Dylan B Jackson
The current study examines the association between early father involvement and infant neurodevelopment, and whether neonatal medical risk moderates this association. Data from approximately 6000 fathers and their children were obtained from the Early Childhood Longitudinal Study: Birth Cohort (ECLS-B). Hierarchical regression was employed to analyze the data. The findings reveal that the association between early father involvement and infant neurodevelopment is contingent on both the timing of involvement (i...
November 22, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/27866648/extracorporeal-life-support-is-safe-in-trauma-patients
#12
Christopher R Burke, Angelena Crown, Titus Chan, D Michael McMullan
INTRODUCTION: The role of extracorporeal life support (ECLS) in the critically ill trauma patient is poorly defined, possibly leading to the underutilization of this lifesaving therapy in this population. This study examined survival rates and risk factors for death in trauma patients who received ECLS. METHODS: Data from the National Trauma Data Bank was retrospectively reviewed to identify trauma patients who received ECLS from January 2012 to December 2014. Clinical outcomes and risk factors for death were examined in these patients...
November 11, 2016: Injury
https://www.readbyqxmd.com/read/27862870/exploring-the-electrochemiluminescent-behavior-of-procaterol-hydrochloride-in-the-presence-of-ru-bpy-3-2-and-its-analytical-application-in-pharmaceutical-preparation
#13
Dexian Kong, Fangdong Hu, Lili Jiang, Jiandi Lin, Qiaohua Wei, Yuwu Chi, Guonan Chen
Based on the strong enhancement effect of procaterol hydrochloride on the electrochemiluminescence (ECL) of Ru(bpy)3(2+) (bpy = 2,2'-bipyridine) in an alkaline H3 PO4 -NaOH buffer solution on a bare Pt electrode, a simple, rapid and sensitive method was developed for the determination of procaterol hydrochloride. The optimum conditions for the enhanced ECL have been developed in detail in this work. Under optimum conditions, the logarithmic ECL enhancement vs. the logarithmic concentration of procaterol hydrochloride is linear over a wide concentration range of 2...
November 15, 2016: Luminescence: the Journal of Biological and Chemical Luminescence
https://www.readbyqxmd.com/read/27862040/central-extracorporeal-life-support-with-left-ventricular-decompression-to-berlin-heart-excor-a-reliable-bridge-to-bridge-strategy-in-crash-and-burn-patients
#14
Alexander Weymann, Mina Farag, Anton Sabashnikov, Javid Fatullayev, Mohamed Zeriouh, Bastian Schmack, Rawa Arif, Florian Müller, Christina Alt, Philip Raake, Nikhil Prakash Patil, Aron-Frederik Popov, Andre Rüdiger Simon, Matthias Karck, Arjang Ruhparwar
The aim of this study was to compare patients with severe biventricular heart failure who underwent Berlin Heart Excor implantation with (cardiogenic shock [CS] status) or without the need for preoperative extracorporeal life support (ECLS) as a bridge to long-term device. A total of 40 consecutive patients with severe biventricular heart failure underwent Berlin Heart Excor implantation with (CS status, n = 20, 50%) or without (control, n = 20, 50%) the need for preoperative ECLS as a bridge to long-term device from March 2007 to May 2015 at our institution...
November 8, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27862035/does-an-open-recirculation-line-affect-the-flow-rate-and-pressure-in-a-neonatal-extracorporeal-life-support-circuit-with-a-centrifugal-or-roller-pump
#15
Shigang Wang, Shannon B Spencer, Karl Woitas, Kristen Glass, Allen R Kunselman, Akif Ündar
The objective of this study is to evaluate the impact of an open or closed recirculation line on flow rate, circuit pressure, and hemodynamic energy transmission in simulated neonatal extracorporeal life support (ECLS) systems. The two neonatal ECLS circuits consisted of a Maquet HL20 roller pump (RP group) or a RotaFlow centrifugal pump (CP group), Quadrox-iD Pediatric oxygenator, and Biomedicus arterial and venous cannulae (8 Fr and 10 Fr) primed with lactated Ringer's solution and packed red blood cells (hematocrit 35%)...
November 15, 2016: Artificial Organs
https://www.readbyqxmd.com/read/27853677/reduced-graphene-oxide-decorated-with-gold-nanoparticle-as-signal-amplification-element-on-ultra-sensitive-electrochemiluminescence-determination-of-caspase-3-activity-and-apoptosis-using-peptide-based-biosensor
#16
Balal Khalilzadeh, Nasrin Shadjou, Hadi Afsharan, Morteza Eskandani, Hojjatollah Nozad Charoudeh, Mohammad-Reza Rashidi
Introduction: Growing demands for ultrasensitive biosensing have led to the development of numerous signal amplification strategies. In this report, a novel electrochemiluminescence (ECL) method was developed for the detection and determination of caspase-3 activity based on reduced graphene oxide sheets decorated by gold nanoparticles as signal amplification element and horseradish peroxidase enzyme (HRP) as ECL intensity enhancing agent. Methods: The ECL intensity of the luminol was improved by using the streptavidin coated magnetic beads and HRP in the presence of hydrogen peroxide...
2016: BioImpacts: BI
https://www.readbyqxmd.com/read/27852542/factors-associated-with-elevated-serum-chromogranin-a-levels-in-patients-with-autoimmune-gastritis
#17
Çağdaş Kalkan, Fatih Karakaya, İrfan Soykan
BACKGROUND/AIMS: Chromogranin A is an important tool in the diagnosis of neuroendocrine tumors. Autoimmune gastritis is an autoimmune disorder marked by hypergastrinemia, which stimulates enterochromaffin-like cell proliferation. Chromogranin A is also elevated in autoimmune gastritis patients with a different level of increase in each patient. The goal of this study is to explore constituents that influence serum chromogranin A levels in autoimmune gastritis patients. MATERIALS AND METHODS: One hundred and eighty-eight autoimmune gastritis patients and 20 patients with type I gastric carcinoid tumors were analyzed retrospectively and compared to 110 functional dyspepsia patients in terms of factors that might affect serum chromogranin A levels...
November 2016: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/27844397/compensation-or-reinforcement-the-stratification-of-parental-responses-to-children-s-early-ability
#18
Michael Grätz, Florencia Torche
Theory and empirical evidence suggest that parents allocate their investments unequally among their children, thus inducing within-family inequality. We investigate whether parents reinforce or compensate for initial ability differences between their children as well as whether these parental responses vary by family socioeconomic status (SES). Using the Early Childhood Longitudinal Study, Birth Cohort (ECLS-B) and a twin fixed-effects approach to address unobserved heterogeneity, we find that parental responses to early ability differences between their children do vary by family SES...
December 2016: Demography
https://www.readbyqxmd.com/read/27837262/outcomes-of-congenital-diaphragmatic-hernia-repair-on-extracorporeal-life-support
#19
Jamie Golden, Nicole Jones, Jessica Zagory, Shannon Castle, David Bliss
PURPOSE: Extracorporeal life support (ECLS) is applied to refractory pulmonary hypertension in congenital diaphragmatic hernia (CDH). We evaluate the single-center outcomes of infants with CDH to determine the utility of late repair on ECLS versus repair post-decannulation. METHODS: Records of infants with CDH (2004-2014) were retrospectively reviewed. RESULTS: CDH was diagnosed in 177 infants. Sixty six (37%) underwent ECLS, of which, 11 died prior to repair, 33 were repaired post-decannulation, and 22 were repaired on ECLS...
November 11, 2016: Pediatric Surgery International
https://www.readbyqxmd.com/read/27829561/enhanced-electrogenerated-chemiluminescence-behavior-of-c3n4-qds-c3n4-nanosheet-and-its-signal-on-aptasensing-for-platelet-derived-growth-factor
#20
Huifeng Xu, Shijing Liang, Xi Zhu, Xiuqin Wu, Yongqiang Dong, Haishan Wu, Wenxia Zhang, Yuwu Chi
A novel g-C3N4 nanosheets embedded with C3N4 QDs nanocomposites (QD@CNNS) was prepared by simple oxidation using hydrogen peroxide and UV light irradiation. This nanocomposite exhibits more stable and stronger electrochemiluminescent (ECL) behavior compared with CNNS. Coupling this nanocomposite with Fc-labeled aptamer, a signal-on aptasensor for platelet derived growth factor BB (PDGF-BB) is fabricated. Initially, the Fc-labeled aptamer binds onto QD@CNNS via π-π conjugation and electrostatic interaction, quenching ECL emission from QD@CNNS...
October 14, 2016: Biosensors & Bioelectronics
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