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Nerve sparing radical hysterectomy

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https://www.readbyqxmd.com/read/28927778/introducing-nerve-sparing-approach-during-minimally-invasive-radical-hysterectomy-for-locally-advanced-cervical-cancer-a-multi-institutional-experience
#1
Francesco Raspagliesi, Giorgio Bogani, Arsenio Spinillo, Antonino Ditto, Stefano Bogliolo, Jvan Casarin, Umberto Leone Roberti Maggiore, Fabio Martinelli, Mauro Signorelli, Barbara Gardella, Valentina Chiappa, Cono Scaffa, Simone Ferrero, Antonella Cromi, Domenica Lorusso, Fabio Ghezzi
OBJECTIVE: To evaluate the impact of nerve-sparing (NS) approach on outcomes of patients undergoing minimally invasive radical hysterectomy (MRH) for locally advanced stage cervical cancer (LACC). METHODS: Data of consecutive patients undergoing minimally invasive surgery for LACC were retrospectively retrieved in a multi-institutional setting from 2009 to 2016. All patients included had minimally invasive class III radical hysterectomy (MRH or NS-MRH). Propensity matching algorithm was used to decrease possible allocation bias when comparing outcomes between groups...
September 7, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28868914/-comparison-of-laparoscopic-and-open-radical-hysterectomies-in-the-surgical-treatment-of-cervical-cancer
#2
COMPARATIVE STUDY
Rudolf Lampé, Róbert Póka
INTRODUCTION: Cervical cancer is one of the most common causes of death among women with malignant tumours. The two most common ways of surgical technique of early stage cervical cancer is the laparoscopy and the laparotomy. AIM: Our aim was to compare the intra- and postoperative results of total laparoscopic radical hysterectomy and abdominal radical hysterectomy. METHOD: Ten nerve sparing laparoscopic and 11 abdominal radical hysterectomies were performed from June 2016 until June 2017 because of early stage cervical cancer...
September 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28708791/self-reported-long-term-autonomic-function-after-laparoscopic-total-mesometrial-resection-for-early-stage-cervical-cancer-a-multicentric-study
#3
Alessandro Lucidi, Swetlana Windemut, Marco Petrillo, Margherita Dessole, Giulio Sozzi, Giuseppe Filiberto Vercellino, Kaven Baessler, Giuseppe Vizzielli, Jalid Sehouli, Giovanni Scambia, Vito Chiantera
OBJECTIVES: This multicentric retrospective study investigates the early and long-term self-reported urinary, bowel, and sexual dysfunctions in early-stage cervical cancer patients who submitted to laparoscopic total mesometrial resection (L-TMMR), total laparoscopic radical hysterectomy, vaginal-assisted laparoscopic radical hysterectomy, and laparoscopic-assisted radical vaginal hysterectomy. METHODS: Cervical cancer patients, FIGO (International Federation of Gynecology and Obstetrics) stage IA2-IB1/IIA1 who submitted to nerve-sparing radical hysterectomy were recruited...
September 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28708591/an-improved-nerve-sparing-radical-hysterectomy-technique-for-cervical-cancer-using-the-paravesico-vaginal-space-as-a-new-surgical-landmark
#4
Yuqin Zhang, Tingyan Shi, Sheng Yin, Sining Ma, Di Shi, Jun Guan, Libing Xiang, Yang Liu, Yulan Ren, Deyan Tan, Rongyu Zang
Bladder dysfunction remains a major postoperative challenge for early stage cervical cancer patients. The present prospective phase 2 trial in patients with stage IB1 and IIA1 cervical cancer follows up on our previous, unpublished work describing a new surgical landmark, the paravesico-vaginal space. We describe a novel nerve-sparing radical hysterectomy (NSRH) approach to treat early stage cervical cancer without compromising local control rate or survival. Between September 2015 and August 2016, 49 patients were enrolled to receive NSRH...
July 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28704329/long-term-oncological-outcome-after-conventional-radical-hysterectomy-versus-2-nerve-sparing-modalities-for-early-stage-cervical-cancer
#5
Mignon Dingena Johanna Maria van Gent, Mandy Rademaker, Johanna Cornelia Bernadette van der Veer, Mariëtte Inie Elizabeth van Poelgeest, Katja Nicoline Gaarenstroom, Hein Putter, Johannes Baptist Maria Zacharias Trimbos, Cor Doede de Kroon
OBJECTIVES: Nerve-sparing radical hysterectomy for early stage cervical cancer was introduced to improve quality of life after treatment. Sparing the pelvic autonomic nerves reduces bladder, bowel, and sexual dysfunction. The Leiden nerve-sparing radical hysterectomy (LNSRH) was modified to the Swift procedure, the latter being more radical regarding the sacrouterine and parametrial resection. We investigate whether nerve-sparing surgery has comparable oncological outcomes as the conventional radical hysterectomy (CRH)...
July 12, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28695641/favorable-factors-for-preserving-bladder-function-after-nerve-sparing-radical-hysterectomy-a-protocol-based-validation-study
#6
Hee Seung Kim, Miseon Kim, Yanlin Luo, Maria Lee, Yong Sang Song
OBJECTIVES: To investigate favorable factors of nerve-sparing radical hysterectomy (NSRH) for preserving the pelvic autonomic nerves and subsequent bladder function and to compare the safety between NSRH and conventional radical hysterectomy (CRH) for cervical cancer. METHODS: We recruited 87 consecutive patients with IB1-IIA cervical cancer who underwent NSRH, and reviewed the information of 81 patients who received CRH for historical comparisons. One gynaecologic oncologist performed all operations...
September 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28625962/application-research-on-nerve-sparing-radical-hysterectomy-for-rectal-function
#7
Yuehui Su, Mengzhen Zhang, Weiwei Zhang, Huirong Shi
This paper aims to discuss the clinical significance of laparotomy nerve sparing radical hysterectomy (NSRH) on rectal function of early cervical cancer patients, compared with conventional radical hysterectomy. 30 cases of early cervical carcinoma patients who had received surgery in the First Affiliated Hospital of Zhengzhou University from June 2010 to June 2014 were selected as subjects. Patients were divided into two groups, with 15 in each gorup, in which Group A had received NSRH, B received CRH, and all them were in stage IB-IIA1...
January 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28498243/a-controlled-study-on-vaginal-blood-flow-during-sexual-arousal-among-early-stage-cervical-cancer-survivors-treated-with-conventional-radical-or-nerve-sparing-surgery-with-or-without-radiotherapy
#8
Rinske Maria Bakker, Quirine D Pieterse, Luc R C W van Lonkhuijzen, Baptist J B M Z Trimbos, Carien L Creutzberg, Gemma G Kenter, Cor D de Kroon, Moniek M Ter Kuile
OBJECTIVE: Sexual problems among cervical cancer survivors may in part be caused by reduced vaginal blood flow due to damaged hypogastric nerves during radical hysterectomy with pelvic lymphadenectomy and/or by radiation-induced vaginal changes after pelvic radiotherapy. A nerve-sparing modification of radical hysterectomy (NSRH) may preserve vaginal blood flow. Vaginal blood flow during sexual arousal was compared between different treatment modalities. METHODS: We investigated premenopausal women treated for early-stage cervical cancer with radical hysterectomy (n = 29), NSRH (n = 28), NSRH with radiotherapy (n = 14), and controls (n = 31)...
June 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28094020/the-wertheim-hysterectomy-development-modifications-and-impact-in-the-present-day
#9
Alexa L Swailes, Allison Gockley, Rébécca Phaëton, Joshua P Kesterson
Ernst Wertheim was a pioneer in the history of the surgical treatment of cervical cancer. His English-language manuscript "The extended abdominal operation for carcinoma uteri (based on 500 operative cases)," which was published in 1912, detailed his standardization of the radical hysterectomy and formed the basis of the current treatment for early stage cervical cancer. We contextualize the Wertheim hysterectomy, emphasizing medical advances that allowed for its development and subsequent modification. We then discuss modifications to the originally proposed procedure, including a maximally extended parametrical resection pioneered by Takayama, and the addition of the Taussig en bloc lymph node dissection by Meigs, both of which afforded an improved mortality profile due to decreased disease recurrence...
April 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/27825032/current-concepts-and-practical-techniques-of-nerve-sparing-laparoscopic-radical-hysterectomy
#10
REVIEW
Satoru Kyo, Tomoyasu Kato, Kentaro Nakayama
Laparoscopic radical hysterectomy has been widely performed for patients with early-stage cervical cancer. The operative techniques for nerve-sparing to avoid bladder dysfunction have been established during the past three decades in abdominal radical hysterectomy, but how these techniques can be applied to laparoscopic surgery has not been fully discussed. Prolonged operation time or decreased radicality due to less accessibility via a limited number of trocars may be a disadvantage of the laparoscopic approach, but the magnified visual field in laparoscopy may enable fine manipulation, especially for preserving autonomic nerve tracts...
December 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27823742/nerve-sparing-radical-hysterectomy-versus-conventional-radical-hysterectomy-in-early-stage-cervical-cancer-a-systematic-review-and-meta-analysis-of-survival-and-quality-of-life
#11
REVIEW
M D J M van Gent, L M Romijn, K E van Santen, J B M Z Trimbos, C D de Kroon
BACKGROUND AND AIMS: Survival after radical hysterectomy (RH) for early-stage cervical cancer is good. Hence quality of life (QOL) after treatment is an important issue. Nerve-sparing radical hysterectomy (NSRH) improves QOL by selectively sparing innervation of bladder, bowel and vagina, reducing therapy-induced morbidity. However, the oncological outcome and the functional outcome after NSRH are subjects of debate. We aim to present the best possible evidence available regarding both QOL and survival after NSRH in early-stage cervical cancer...
December 2016: Maturitas
https://www.readbyqxmd.com/read/27679338/a-preliminary-report-of-a-prospective-randomized-controlled-study-effects-of-water-jet-in-laparoscopic-nerve-sparing-radical-hysterectomy-for-patients-with-cervical-cancer
#12
M Wu, S Q Ma, X J Tan
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678860/robotic-assisted-laparoscopic-nerve-sparing-radical-hysterectomy
#13
H Xu, Y Chen, Y Wang, Z Liang
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27678605/total-laparoscopic-nerve-sparing-radical-hysterectomy-for-cervical-cancer-and-retossigmoidectomy-for-deep-intestinal-endometriosis-in-a-patient-with-uterus-didelphys
#14
R Ribeiro, W Kondo, Luz M A, R M Hayashi, Mtz Kondo
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27568405/-anatomical-consideration-for-the-technique-of-nerve-sparing-during-radical-hysterectomy-for-cervical-cancer
#15
V Balaya, C Ngo, L Rossi, C Cornou, C Bensaid, R Douard, A S Bats, F Lecuru
Radical hysterectomy (RH) is an effective treatment for early-stage cervical cancer IA2 to IIA1 but RH is often associated with several significant complications such as urinary, anorectal and sexual dysfunction due to pelvic nerve injuries. Pelvic autonomic nerves including the superior hypogastric plexus (SHP), hypogastric nerves (HN), pelvic splanchnic nerves (PSN), sacral splanchnic nerves (SSN), inferior hypogastric plexus (IHP) and efferent branches of the IHP. We aimed to precise the neuroanatomy of the female pelvis in order to provide key-points of surgical anatomy to improve NSRH for cervical cancer...
September 2016: Gynécologie, Obstétrique & Fertilité
https://www.readbyqxmd.com/read/27519967/outpatient-laparoscopic-nerve-sparing-radical-hysterectomy-a-feasibility-study-and-analysis-of-perioperative-outcomes
#16
Gabriel J Rendón, Lina Echeverri, Francisco Echeverri, Carlos Millán Sanz-Lomana, Pedro T Ramirez, Rene Pareja
OBJECTIVE: The goal of our study was to report on the feasibility of outpatient laparoscopic radical hysterectomy in patients with early-stage cervical cancer. METHODS: We included all patients who underwent a laparoscopic radical hysterectomy at the Instituto de Cancerología - Las Americas in Medellin, Colombia, between January 2013 and July 2015. The control group was a similar cohort of patients who were admitted after their surgery. RESULTS: Seventy-six patients were included [outpatient (31) and admitted (45)]...
November 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27519498/laparoscopic-nerve-sparing-radical-hysterectomy-for-bulky-cervical-cancer-%C3%A2-6%C3%A2-cm-after-neoadjuvant-chemotherapy-a-multicenter-prospective-cohort-study
#17
MULTICENTER STUDY
Yongxiu Yang, Tiansheng Qin, Wei Zhang, Qiyan Wu, Aihong Yang, Feixue Xu
OBJECTIVE: The study aimed to evaluate the clinical outcomes of laparoscopic nerve-sparing radical hysterectomy (LNRH) for bulky-stage cervical cancer (lesion ≥ 6 cm) after neoadjuvant chemotherapy (NAC). METHODS: This study prospective recruited patients with pathology-confirmed cervical cancer presenting as a bulky mass (lesion ≥ 6 cm). Subjects included patients who underwent laparoscopic radical surgery. They were assigned to one of two groups by surgical method: patients who underwent LNRH after NAC and patients who underwent classical laparoscopic radical hysterectomy (LRH) after NAC...
October 2016: International Journal of Surgery
https://www.readbyqxmd.com/read/27465892/long-term-pelvic-floor-function-and-quality-of-life-after-radical-surgery-for-cervical-cancer-a-multicenter-comparison-between-different-techniques-for-radical-hysterectomy-with-pelvic-lymphadenectomy
#18
Marloes Derks, Jacobus van der Velden, Minke M Frijstein, Willemijn M Vermeer, Anne M Stiggelbout, Jan Paul W R Roovers, Cornelis D de Kroon, Moniek M Ter Kuile, Gemma G Kenter
OBJECTIVE: This study aimed to compare urinary and bowel symptoms and quality of life (QoL) among women treated with a Wertheim-Meigs (WM, type III) or Wertheim-Okabayashi (WO, type IV) radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer. METHODS: In this cross-sectional observational study, patients treated with a WO or a (nerve sparing) WM radical hysterectomy (with or without adjuvant radiotherapy) between January 2000 and December 2010 in the Center for Gynaecological Oncology Amsterdam or Leiden University Medical Center were included...
October 2016: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27373783/incorporating-3d-laparoscopy-for-the-management-of-locally-advanced-cervical-cancer-a-comparison-with-open-surgery
#19
Francesco Raspagliesi, Giorgio Bogani, Fabio Martinelli, Mauro Signorelli, Valentina Chiappa, Cono Scaffa, Ilaria Sabatucci, Marco Adorni, Domenica Lorusso, Antonino Ditto
PURPOSE: To test the effects of the implementation of 3D laparoscopic technology for the execution of nerve-sparing radical hysterectomy. METHODS: Thirty patients undergoing nerve-sparing radical hysterectomy via 3D laparoscopic (3D-LNSRH, n = 10) or open surgery (NSRH, n = 20) were studied prospectively. RESULTS: No significant differences were observed in baseline patient characteristics. Operative times were similar between groups. We compared the first 10 patients undergoing 3D-LNSRH with the last 20 patients undergoing NSRH...
August 3, 2016: Tumori
https://www.readbyqxmd.com/read/27160267/comparison-of-nerve-sparing-radical-hysterectomy-and-radical-hysterectomy-a-systematic-review-and-meta-analysis
#20
REVIEW
Zhuowei Xue, Xiaolu Zhu, Yincheng Teng
BACKGROUND/AIMS: Radical hysterectomy (RH) for the treatment of cervical cancer frequently caused pelvic organ dysfunctions. This study aimed to compare the results of pelvic organ function and recurrence rate after Nerve sparing radical hysterectomy (NSRH) and RH treatment through systematic review and meta-analysis. METHODS: PubMed, Web of Science and China Knowledge Resource Integrated Database were searched from inception to 25 February 2015. Studies of cervical cancer which reported radical hysterectomy or nerve sparing radical hysterectomy were included...
2016: Cellular Physiology and Biochemistry
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