Read by QxMD icon Read

Nerve sparing radical hysterectomy

Alexa L Swailes, Allison Gockley, Rébécca Phaëton, Joshua P Kesterson
Ernst Wertheim was a pioneer in the history of the surgical treatment of cervical cancer. His English-language manuscript "The extended abdominal operation for carcinoma uteri (based on 500 operative cases)," which was published in 1912, detailed his standardization of the radical hysterectomy and formed the basis of the current treatment for early stage cervical cancer. We contextualize the Wertheim hysterectomy, emphasizing medical advances that allowed for its development and subsequent modification. We then discuss modifications to the originally proposed procedure, including a maximally extended parametrical resection pioneered by Takayama, and the addition of the Taussig en bloc lymph node dissection by Meigs, both of which afforded an improved mortality profile due to decreased disease recurrence...
January 13, 2017: Gynecologic Oncology
Satoru Kyo, Tomoyasu Kato, Kentaro Nakayama
Laparoscopic radical hysterectomy has been widely performed for patients with early-stage cervical cancer. The operative techniques for nerve-sparing to avoid bladder dysfunction have been established during the past three decades in abdominal radical hysterectomy, but how these techniques can be applied to laparoscopic surgery has not been fully discussed. Prolonged operation time or decreased radicality due to less accessibility via a limited number of trocars may be a disadvantage of the laparoscopic approach, but the magnified visual field in laparoscopy may enable fine manipulation, especially for preserving autonomic nerve tracts...
December 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
M D J M van Gent, L M Romijn, K E van Santen, J B M Z Trimbos, C D de Kroon
BACKGROUND AND AIMS: Survival after radical hysterectomy (RH) for early-stage cervical cancer is good. Hence quality of life (QOL) after treatment is an important issue. Nerve-sparing radical hysterectomy (NSRH) improves QOL by selectively sparing innervation of bladder, bowel and vagina, reducing therapy-induced morbidity. However, the oncological outcome and the functional outcome after NSRH are subjects of debate. We aim to present the best possible evidence available regarding both QOL and survival after NSRH in early-stage cervical cancer...
December 2016: Maturitas
M Wu, S Q Ma, X J Tan
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
H Xu, Y Chen, Y Wang, Z Liang
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
R Ribeiro, W Kondo, Luz M A, R M Hayashi, Mtz Kondo
No abstract text is available yet for this article.
November 2015: Journal of Minimally Invasive Gynecology
V Balaya, C Ngo, L Rossi, C Cornou, C Bensaid, R Douard, A S Bats, F Lecuru
Radical hysterectomy (RH) is an effective treatment for early-stage cervical cancer IA2 to IIA1 but RH is often associated with several significant complications such as urinary, anorectal and sexual dysfunction due to pelvic nerve injuries. Pelvic autonomic nerves including the superior hypogastric plexus (SHP), hypogastric nerves (HN), pelvic splanchnic nerves (PSN), sacral splanchnic nerves (SSN), inferior hypogastric plexus (IHP) and efferent branches of the IHP. We aimed to precise the neuroanatomy of the female pelvis in order to provide key-points of surgical anatomy to improve NSRH for cervical cancer...
September 2016: Gynécologie, Obstétrique & Fertilité
Gabriel J Rendón, Lina Echeverri, Francisco Echeverri, Carlos Millán Sanz-Lomana, Pedro T Ramirez, Rene Pareja
OBJECTIVE: The goal of our study was to report on the feasibility of outpatient laparoscopic radical hysterectomy in patients with early-stage cervical cancer. METHODS: We included all patients who underwent a laparoscopic radical hysterectomy at the Instituto de Cancerología - Las Americas in Medellin, Colombia, between January 2013 and July 2015. The control group was a similar cohort of patients who were admitted after their surgery. RESULTS: Seventy-six patients were included [outpatient (31) and admitted (45)]...
November 2016: Gynecologic Oncology
Yongxiu Yang, Tiansheng Qin, Wei Zhang, Qiyan Wu, Aihong Yang, Feixue Xu
OBJECTIVE: The study aimed to evaluate the clinical outcomes of laparoscopic nerve-sparing radical hysterectomy (LNRH) for bulky-stage cervical cancer (lesion ≥ 6 cm) after neoadjuvant chemotherapy (NAC). METHODS: This study prospective recruited patients with pathology-confirmed cervical cancer presenting as a bulky mass (lesion ≥ 6 cm). Subjects included patients who underwent laparoscopic radical surgery. They were assigned to one of two groups by surgical method: patients who underwent LNRH after NAC and patients who underwent classical laparoscopic radical hysterectomy (LRH) after NAC...
October 2016: International Journal of Surgery
Marloes Derks, Jacobus van der Velden, Minke M Frijstein, Willemijn M Vermeer, Anne M Stiggelbout, Jan Paul W R Roovers, Cornelis D de Kroon, Moniek M Ter Kuile, Gemma G Kenter
OBJECTIVE: This study aimed to compare urinary and bowel symptoms and quality of life (QoL) among women treated with a Wertheim-Meigs (WM, type III) or Wertheim-Okabayashi (WO, type IV) radical hysterectomy with pelvic lymphadenectomy for early-stage cervical cancer. METHODS: In this cross-sectional observational study, patients treated with a WO or a (nerve sparing) WM radical hysterectomy (with or without adjuvant radiotherapy) between January 2000 and December 2010 in the Center for Gynaecological Oncology Amsterdam or Leiden University Medical Center were included...
October 2016: International Journal of Gynecological Cancer
Francesco Raspagliesi, Giorgio Bogani, Fabio Martinelli, Mauro Signorelli, Valentina Chiappa, Cono Scaffa, Ilaria Sabatucci, Marco Adorni, Domenica Lorusso, Antonino Ditto
PURPOSE: To test the effects of the implementation of 3D laparoscopic technology for the execution of nerve-sparing radical hysterectomy. METHODS: Thirty patients undergoing nerve-sparing radical hysterectomy via 3D laparoscopic (3D-LNSRH, n = 10) or open surgery (NSRH, n = 20) were studied prospectively. RESULTS: No significant differences were observed in baseline patient characteristics. Operative times were similar between groups. We compared the first 10 patients undergoing 3D-LNSRH with the last 20 patients undergoing NSRH...
August 3, 2016: Tumori
Zhuowei Xue, Xiaolu Zhu, Yincheng Teng
BACKGROUND/AIMS: Radical hysterectomy (RH) for the treatment of cervical cancer frequently caused pelvic organ dysfunctions. This study aimed to compare the results of pelvic organ function and recurrence rate after Nerve sparing radical hysterectomy (NSRH) and RH treatment through systematic review and meta-analysis. METHODS: PubMed, Web of Science and China Knowledge Resource Integrated Database were searched from inception to 25 February 2015. Studies of cervical cancer which reported radical hysterectomy or nerve sparing radical hysterectomy were included...
2016: Cellular Physiology and Biochemistry
Juliane Kruppa, Tilemachos Kavvadias, Stefanie Amann, Kaven Baessler, Bernhard Schuessler
OBJECTIVE: The aim of this study was to compare pre- and postoperative bladder function and quality of life (QoL) in women diagnosed with gynecologic malignancy and treated with nerve sparing radical hysterectomy (NSRH). STUDY DESIGN: Before and after NSRH for uterine malignancy, bladder function was prospectively assessed in a small cohort of 12 women (39-72 years) suffering from uterine malignancy using urodynamic studies and a validated self-administered condition specific QoL questionnaire...
June 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Anne C Kraima, Marloes Derks, Noeska N Smit, Cornelis J H van de Velde, Gemma G Kenter, Marco C DeRuiter
OBJECTIVE: Radical hysterectomy with pelvic lymphadenectomy (RHL) is the preferred treatment for early-stage cervical cancer. Although oncological outcome is good with regard to recurrence and survival rates, it is well known that RHL might result in postoperative bladder impairments due to autonomic nerve disruption. The pelvic autonomic network has been extensively studied, but the anatomy of nerve fibers branching off the inferior hypogastric plexus to innervate the bladder is less known...
June 2016: International Journal of Gynecological Cancer
Min Hao, Zhilian Wang, Fang Wei, Jingfang Wang, Wei Wang, Yi Ping
OBJECTIVE: Pelvic autonomic nerve preservation during radical hysterectomy for cervical cancer has become a priority in recent years. This pilot study was undertaken to evaluate laparoscopic nerve-sparing radical hysterectomy (L-NSRH) using the Cavitron Ultrasonic Surgical Aspirator (CUSA) in women with cervical cancer. METHODS: Patients with stage IB1 or IIA1 cervical cancer underwent L-NSRH with pelvic lymphadenectomy. The patients were randomly assigned to receive L-NSRH using a CUSA (CUSA group; n = 24) or using other techniques (non-CUSA group; n = 21)...
March 2016: International Journal of Gynecological Cancer
F Aoun, S Albisinni, A Peltier, A Maoula, R van Velthoven, T Roumeguère
INTRODUCTION: Radical hysterectomy represents the cornerstone in the management of localized cervical cancer. Despite its oncologic efficacy, radical hysterectomy is associated with a significant amount of complications and a negative impact on quality of life. Surgical technique seems to influence the functional outcomes. AIM OF THE STUDY: A systematic review to provide an update on the lower urinary tract dysfunction following nerve sparing radical hysterectomy...
November 19, 2015: Progrès en Urologie
Zhongyu Liu, Xiuli Li, Ye Tao, Weiping Li, Yizhuo Yang, Yuanqing Yao, Tongyu Zhu
OBJECTIVE: To evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy (LNRH) for locally advanced cervical cancer (LACC) after neoadjuvant chemotherapy (NACT). METHODS: 120 patients with stage Ib2 and IIa2 cervical cancer were treated with surgery combined with preoperative NACT in the Department of Obstetrics and Gynecology, PLA General Hospital. Eligible patients were divided into two groups according to surgery type: patients who underwent LNRH were assigned to one group, while the second group included patients who underwent laparoscopic radical hysterectomy (LRH) after administration of NACT...
January 2016: International Journal of Surgery
Ruxia Shi, Weiwei Wei, Pengcheng Jiang
OBJECTIVE: To evaluate the histopathology of autonomic nerve removal within the cardinal ligaments (CLs), patients' postoperative urinary function, and the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy (LNSRH) for treatment of early-stage cervical cancer. METHODS: Perioperative and postoperative parameters were compared between patients with biopsy-proven, early-stage cervical carcinoma treated with LNSRH (n = 64) versus those treated with laparoscopic radical hysterectomy (LRH, n = 42) in a retrospective study...
January 2016: International Journal of Gynecological Cancer
Zhongyu Liu, Xiuli Li, Weiping Li, Yizhuo Yang, Ye Tao, Yuanqing Yao
OBJECTIVE: To evaluate the feasibility and safety of robotic nerve-sparing radical hysterectomy for locally advanced cervical cancer (LACC). METHODS: In a retrospective study, data were analyzed for patients treated for cervical cancer at a center in Beijing, China, between December 2011 and September 2013. Patients were subdivided into those with early-stage disease (FIGO stage IA2-IB1) who were treated by robotic surgery (group 1), and those with LACC (stage IB2-IIB) who were treated by robotic surgery after neoadjuvant chemotherapy (NACT; group 2)...
November 2015: International Journal of Gynaecology and Obstetrics
I V Berlev, E A Ulrikh, E N Korolkova, Z N Ibragimov, N O Kashina, G I Mikhailyuk, A V Khadzhimba, A F Urmancheeva
Cervical cancer is the most common cancer of the female reproductive system up to 20% of malignant tumors of the female genital organs. Surgery is the main method in treatment for local cervical cancer but postoperative complications often are associated with dysfunction of the pelvic organs. Some researchers focus their attention on the preservation of the pelvic innervation without loss of surgery's radicalism, which is represented in this survey. The paper presents the results of comparative analysis of 54 cases of surgical treatment for invasive cervical cancer...
2015: Voprosy Onkologii
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"