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Distraction osteogenesis

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https://www.readbyqxmd.com/read/28416096/treatment-outcomes-of-archwise-distraction-osteogenesis-in-mandibular-dentoalveolar-retrognathia-cases
#1
C Yöndem, Y B Acar, B C Şener, A N Erverdi
The aim of this study was to describe the treatment of class II malocclusion by sagittal advancement of the alveolar bone in the symphyseal area using an intraoral archwise distractor device and to determine the effects of this method on the dentoalveolar complex. Fifteen patients (10 female, five male) aged 16-20 years with a class II division 2 malocclusion, characterized by mandibular dentoalveolar retrusion and a prominent chin, underwent archwise alveolar distraction in the anterior mandible. Lateral cephalometric radiographs were obtained before distraction (T0), after 6 weeks of consolidation (T1), and after debonding (T2)...
April 13, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28410886/the-autogenous-graft-versus-transport-distraction-osteogenesis-for-reconstruction-of-the-ramus-condyle-unit-a-prospective-comparative-study
#2
S Kohli, S Mohanty, S Singh, Sandeep, J Dabas, R Patel
This study aimed to compare the joint function and morphology achieved following condylar reconstruction using sternoclavicular grafts (SCG) versus transport distraction osteogenesis (TDO) in temporomandibular joint (TMJ) ankylosis patients. Twenty-two patients with TMJ ankylosis underwent TMJ reconstruction with SCG or TDO (n=11 each). Radiographic and clinical evaluations were performed at 1 week and at 1, 3, and 6 months post-surgery. Clinical criteria examined included the duration of surgery, mean postoperative mouth opening, excursive jaw movements, and pain scores...
April 11, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28410841/contemporary-surgical-management-of-hypodontia
#3
REVIEW
J Breeze, M S Dover, R W Williams
Hypodontia is the term most commonly applied to the condition in which teeth congenitally fail to develop. Such cases differ from teeth that have been lost early or that have failed to erupt, although their initial presentation may be similar and therefore not recognised. The range of missing teeth and their physical and psychological results is large, and the difference in complexity in the management of a patient with isolated hypodontia compared with one with oligodontia or anodontia together with skeletal and orthognathic discrepancies should not be underestimated...
April 11, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28407179/effect-of-gene-transfection-timing-on-tgf-%C3%AE-1-expression-in-rabbit-mandibular-distraction-gap
#4
M-K Xie, C-B Hu, B Zhou, G-P Wu
Transforming growth factor-β1 (TGF-β1) is a member of the TGF-β superfamily, and plays an important role in promoting various stages of intramembranous and endochondral bone formation. It is one of the major growth factors that influence new bone formation in the distraction gap during distraction osteogenesis (DO). The major problem of DO is the time required for the treatment. Reports show that gene therapy accelerates osteogenesis, which can significantly benefit patients with DO. However, the optimal timing of gene transfection has not yet been reported...
April 13, 2017: Genetics and Molecular Research: GMR
https://www.readbyqxmd.com/read/28403134/early-computer-aided-design-computer-aided-modeling-planned-le-fort-i-advancement-with-internal-distractors-to-treat-severe-maxillary-hypoplasia-in-cleft-lip-and-palate
#5
Catherine S Chang, Jordan Swanson, Jason Yu, Jesse A Taylor
Traditionally, maxillary hypoplasia in the setting of cleft lip and palate is treated via orthognathic surgery at skeletal maturity, which condemns these patients to abnormal facial proportions during adolescence. The authors sought to determine the safety profile of computer-aided design/computer-aided modeling (CAD/CAM) planned, Le Fort I distraction osteogenesis with internal distractors in select patients presenting at a young age with severe maxillary retrusion. The authors retrospectively reviewed our "early" Le Fort I distraction osteogenesis experience-patients performed for severe maxillary retrusion (≥12 mm underjet), after canine eruption but prior to skeletal maturity-at a single institution...
April 11, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28403000/the-combined-use-of-a-neurocutaneous-flap-and-the-ilizarov-technique-for-reconstruction-of-large-soft-tissue-defects-and-bone-loss-in-the-tibia
#6
Jia Xu, Wan-Run Zhong, Liang Cheng, Chun-Yang Wang, Gen Wen, Pei Han, Yi-Min Chai
BACKGROUND: Management of posttraumatic large soft tissue defects and bone loss remains a therapeutic and surgical challenge for orthopedic surgeons. We assessed the use of a neurocutaneous flap and the Ilizarov technique in the reconstruction of severe composite defects in the tibia. METHODS: We retrospectively reviewed 18 consecutive patients with trauma-related soft tissue defects and bone loss. The size of the soft tissue defect ranges from 8 × 9 cm to 14 × 18 cm...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28400671/distraction-osteogenesis-using-combined-locking-plate-and-ilizarov-fixator-in-the-treatment-of-bone-defect-a-report-of-2-cases
#7
John Mukhopadhaya, Manish Raj
Distraction osteogenesis and bone transport has been used to reconstruct bone loss defect by allowing new bone to form in the gap. Plate-guided bone transport has been successfully described in literature to treat bone loss defect in the femur, tibia, and mandible. This study reports two cases of fracture of femur with segmental bone loss treated with locking plate fixation and bone transport with Ilizarov ring fixator. At the time of docking, when the transport segment is compressed with bone fragment, the bone fragment is fixed with additional locking or nonlocking screws through the plate...
March 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28390758/alternative-distraction-osteogenesis-technique-after-implant-placement-for-alveolar-ridge-augmentation-of-the-maxilla
#8
Renato Luiz Maia Nogueira, Rafael Lima Verde Osterne, Ricardo Teixeira Abreu, Phelype Maia Araújo
An alternative technique to reconstruct atrophic alveolar vertical bone after implant placement is presented. The technique consists of distraction osteogenesis or direct surgical repositioning of an implant-and-bone block segment after segmental osteotomies that can be used in esthetic or unesthetic cases. Initially, casts indicating the implant position are obtained and the future ideal prosthetic position is determined to guide the model surgery. After the model surgery, a new provisional prosthesis is fabricated, and an occlusal splint, which is used as a surgical guide and a device for distraction osteogenesis, is custom fabricated...
March 18, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28385939/low-intensity-pulsed-ultrasound-does-not-influence-bone-healing-by-distraction-osteogenesis-a-multicentre-double-blind-randomised-control-trial
#9
A H R W Simpson, G Keenan, S Nayagam, R M Atkins, D Marsh, N D Clement
AIMS: The aim of this double-blind prospective randomised controlled trial was to assess whether low intensity pulsed ultrasound (LIPUS) accelerated or enhanced the rate of bone healing in adult patients undergoing distraction osteogenesis. PATIENTS AND METHODS: A total of 62 adult patients undergoing limb lengthening or bone transport by distraction osteogenesis were randomised to treatment with either an active (n = 32) or a placebo (n = 30) ultrasound device...
April 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28372992/the-effects-of-clinical-factors-on-airway-outcomes-of-mandibular-distraction-osteogenesis-in-children-with-pierre-robin-sequence
#10
REVIEW
X C Ren, Z W Gao, Y F Li, Y Liu, B Ye, S S Zhu
Mandibular distraction osteogenesis (MDO) is an effective treatment for tongue-based airway obstruction in children with severe Pierre Robin sequence. An investigation was performed to determine whether certain clinical factors influence the airway outcomes of MDO. A literature search of several databases was performed to identify studies providing individual patient data. Data extracted from the studies included patient sex, age at distraction, disease type, experience of any previous surgery on the airway, length of distraction, pre- and postoperative blood oxygen saturation nadir, and osteotomy design...
March 31, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28364902/orthodontic-and-surgical-management-of-a-patient-with-severe-skeletal-class-ii-deformity-and-facial-asymmetry-a-case-report-with-a-5-year-follow-up
#11
Xiang Gao, Tao Wang, Jinlin Song
In this case report, we present the orthodontic and surgical management of an 18-year-old girl who had a severe craniofacial deformity, including maxillary prognathism, vertical maxillary excess (gummy smile), mandibular retrognathism, receding chin, and facial asymmetry caused by unilateral temporomandibular joint ankylosis. For correction of the facial asymmetry, the patient's right mandibular ramus and body were lengthened via distraction osteogenesis after 5 months of preoperative orthodontic therapy. Subsequently, extraction of 4 first premolars, bimaxillary anterior segmental osteotomy, and genioplasty were simultaneously performed in the second-stage operation to correct the skeletal deformities in the sagittal and vertical planes...
April 2017: American Journal of Orthodontics and Dentofacial Orthopedics
https://www.readbyqxmd.com/read/28359687/comparison-of-the-adult-three-dimensional-craniofacial-features-of-patients-with-unilateral-craniofacial-microsomia-with-and-without-early-mandible-distraction
#12
E W-C Ko, P K-T Chen, L-J Lo
This study was conducted to analyze the long-term facial growth of patients with craniofacial microsomia (CFM) after early mandible distraction osteogenesis (DO), and compared adult three-dimensional (3D) craniofacial features of patients with and without early mandibular DO for Pruzansky grade II deformities. The study included 20 patients: 9 with early mandible DO (the DO group) and 11 without previous treatment (the NDO group). Longitudinal radiographs were measured for growth changes after DO. The 3D craniofacial images were constructed to compare the craniofacial forms between the two groups...
March 27, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28359544/corrigendum-to-effect-of-platelet-rich-plasma-in-alveolar-distraction-osteogenesis-a-controlled-clinical-trial-british-journal-of-oral-and-maxillofacial-surgery-54-1-2016-83-87
#13
Diogo J B Menezes, Jamil Awad Shibli, Sergio Alexandre Gehrke, Andréa M Beder, Wilson R Sendyk
No abstract text is available yet for this article.
March 27, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/28351547/the-road-to-union-protocol-for-the-reconstruction-of-isolated-complex-high-energy-tibial-trauma
#14
Erik Hohmann, Franz Birkholtz, Vaida Glatt, Kevin Tetsworth
INTRODUCTION: The purpose of this study was to describe a standardized staged approach, "The Road to Union", for the reconstruction of isolated complex tibial trauma, both acute and chronic in nature. METHODS: This retrospective study included all patients treated for complex tibial trauma at a specialized limb reconstruction centre, including acute open fracture as well as infected and aseptic non-unions. This standardized approach includes eight specific steps, employed in sequence...
March 18, 2017: Injury
https://www.readbyqxmd.com/read/28350680/airway-and-feeding-outcomes-of-mandibular-distraction-tongue-lip-adhesion-and-conservative-management-in-pierre-robin-sequence-a-prospective-study
#15
Ibrahim Khansa, Courtney Hall, Lauren L Madhoun, Mark Splaingard, Adriane Baylis, Richard E Kirschner, Gregory D Pearson
BACKGROUND: Pierre Robin sequence is characterized by mandibular retrognathia and glossoptosis resulting in airway obstruction and feeding difficulties. When conservative management fails, mandibular distraction osteogenesis or tongue-lip adhesion may be required to avoid tracheostomy. The authors' goal was to prospectively evaluate the airway and feeding outcomes of their comprehensive approach to Pierre Robin sequence, which includes conservative management, mandibular distraction osteogenesis, and tongue-lip adhesion...
April 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28350556/resorbable-plates-prevent-regression-in-pediatric-mandibular-distraction-osteogenesis
#16
Brandon Kikuo Richland, Christopher Ellstrom, Asim Ahmad, Daniel Jaffurs
BACKGROUND: Mandibular distraction osteogenesis is an important technique to correct the pediatric hypoplastic mandible. Regression of the mandible after distraction continues to be a challenge, with some studies reporting up to 22% to 56% decrease toward predistraction length in the first year. We hypothesize that a resorbable plate placed after removal of the distractor will provide additional stability to newly formed bone, allowing further time for consolidation and minimizing regression...
May 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28347627/simulation-guided-navigation-for-vector-control-in-pediatric-mandibular-distraction-osteogenesis
#17
Giovanni Badiali, Fabrizio Cutolo, Andrea Roncari, Claudio Marchetti, Alberto Bianchi
AIM: Navigation technology has given surgeons the capacity to know precisely where their instruments are during surgery, and simulation-guided navigation is a surgical method which is based on the use of navigation technology linked to 3D virtual surgery simulation. The aim of the present study was to evaluate the absolute accuracy of simulation-guided navigation as an aid to reproduce the planned position of the distraction device vector in pediatric mandibular distraction osteogenesis...
February 14, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28346008/wnt-%C3%AE-catenin-signaling-is-required-for-distraction-osteogenesis-in-rats
#18
Xuemei Wang, En Luo, Ruiye Bi, Bin Ye, Jing Hu, Shujuan Zou
OVERVIEW: The Wnt signaling pathway plays crucial roles in embryonic skeletal development and postnatal bone regeneration. However, mechanisms of Wnt signaling functioning in distraction osteogenesis (DO) haven't been well characterized. MATERIALS AND METHODS: We established a DO model using Sprague-Dawley rat tibia. And a Wnt signaling blocking agent, recombinant rat Dickkopf-related protein 1 (rrDkk1), was locally applied in the distracted gap to study the role of Wnt signaling during DO process...
March 1, 2017: Connective Tissue Research
https://www.readbyqxmd.com/read/28341855/mir-503-promotes-bone-formation-in-distraction-osteogenesis-through-suppressing-smurf1-expression
#19
Yuxin Sun, Jia Xu, Liangliang Xu, Jinfang Zhang, Kaiming Chan, Xiaohua Pan, Gang Li
Distraction osteogenesis (DO) is a unique technique for promoting bone formation in clinical practice. However the underlying mechanism remains elusive. As epigenetic mediators, microRNAs have been reported to play important roles in regulating osteogenesis. In this study, after successfully established the DO model of rats, a microRNA microarray was performed to find molecular targets for DO. Total 100 microRNAs were identified as differently expressed, with miR-503 being one of the most significantly up-regulated miRNAs in DO...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28338248/surgical-strategy-for-apert-syndrome-retrospective-study-of-developmental-quotient-and-three-dimensional-computerized-tomography
#20
Shoichi Tomita, Takeshi Miyawaki, Yuichirou Nonaka, Shinsuke Sakai, Reiji Nishimura
There are many surgical techniques for craniosynostosis. However, the indications for and timing of surgery still remain unclarified. Most of the skull growth in craniosynostosis is completed in the first year, and the bone is strong enough to undergo distraction osteogenesis. However, previous reports showed that patients operated on before 1 year of age had better IQ than those operated later in life. This report aims to consider the best timing for cranial expansion and surgical strategy for Apert syndrome...
March 24, 2017: Congenital Anomalies
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