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Distraction osteogenesis

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https://www.readbyqxmd.com/read/29155725/an-efficient-and-reproducible-protocol-for-distraction-osteogenesis-in-a-rat-model-leading-to-a-functional-regenerated-femur
#1
Martine Pithioux, Flavy Roseren, Christian Jalain, Franck Launay, Philippe Charpiot, Patrick Chabrand, Sandrine Roffino, Edouard Lamy
This protocol describes the use of a newly developed external fixator for distraction osteogenesis in a rat femoral model. Distraction osteogenesis (DO) is a surgical technique leading to bone regeneration after an osteotomy. The osteotomized extremities are moved away from each other by gradual distraction to reach the desired elongation. This procedure is widely used in humans for lower and upper limb lengthening, treatment after a bone nonunion, or the regeneration of a bone defect following surgery for bone tumor excision, as well as in maxillofacial reconstruction...
October 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29153233/temporomandibular-joint-reconstruction-in-the-growing-child
#2
REVIEW
Cory M Resnick
Indications and considerations for reconstruction of the temporomandibular joint (TMJ) differ between growing and skeletally mature patients. Osteoarthritis, which is the most common cause of TMJ destruction in adults, is comparatively rare in children. The most common indications in young patients are congenital deformities, pathology, ankylosis and progressive resorptive processes. Options for reconstruction include distraction osteogenesis, autologous reconstruction (ie, costochondral graft, free fibula flap), and total alloplastic joint replacement...
February 2018: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/29142868/protrusive-maxillomandibular-fixation-for-intracapsular-condylar-fracture-a-report-of-two-cases
#3
Yeong Kon Jeong, Won-Jong Park, Il Kyung Park, Gi Tae Kim, Eun Joo Choi
Clinical limitations following closed reduction of an intracapsular condylar fracture include a decrease in maximum mouth opening, reduced range of mandibular movements such as protrusion/lateral excursion, and reduced occlusal stability. Anteromedial and inferior displacement of the medial condyle fragment by traction of the lateral pterygoid muscle can induce bone overgrowth due to distraction osteogenesis between the medial and lateral condylar fragments, causing structural changes in the condyle. In addition, when conventional maxillomandibular fixation (MMF) is performed, persistent interdental contact sustains masticatory muscle hyperactivity, leading to a decreased vertical dimension and premature contact of the posterior teeth...
October 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/29135733/treatment-of-maxillary-hypoplasia-in-cleft-lip-and-palate-segmental-distraction-osteogenesis-with-hyrax-device
#4
Rodrigo Fariña, Alejandro Diaz, Roberto Pantoja, Carolina Bidart
The objective of this work is to describe a segmental maxillary distraction osteogenesis (SDO) with segmental Lefort I with an inexpensive device.Four patients who presented severe class III and maxillary hypoplasia due to cleft lip and palate sequel were treated. A SDO was performed using a dental-anchored Hyrax device, achieving enlargement of the upper jaw without altering speech, with adequate and stable occlusion. Dental implants in a new formed bone were installed.The authors can conclude that SDO is a good treatment alternative for patients with maxillary hypoplasia...
November 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29126770/effects-of-unilateral-vertical-mandibular-distraction-osteogenesis-on-airway-anatomy-in-children-with-hemifacial-microsomia
#5
Navid Pourtaheri, Derek Z Wang, Srinivas M Susarla, Gerhard S Mundinger, Anand R Kumar
PURPOSE: To assess the two- and three-dimensional airway changes following unilateral vertical mandibular distraction osteogenesis (vMDO) in patients with hemifacial microsomia (HFM). METHODS: A retrospective evaluation was performed for consecutive patients over an 18-month period with HFM and with Kaban-Pruzansky Type-II mandibular deformities who underwent unilateral vMDO for correction of vertical mandibular asymmetry. Patients with complete records and a minimum of 12 months of clinical follow-up post-consolidation were included...
October 13, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29126455/micrognathia-with-temporomandibular-joint-ankylosis-and-obstructive-sleep-apnea-treated-with-mandibular-distraction-osteogenesis-using-skeletal-anchorage-a-case-report
#6
Hiroshi Tomonari, Hiroko Takada, Tomofumi Hamada, Sangho Kwon, Tsuyoshi Sugiura, Shouichi Miyawaki
BACKGROUND: We describe the case of a 16-year-old female patient with micrognathia, temporomandibular joint (TMJ) ankylosis, and obstructive sleep apnea, who was treated with mandibular distraction osteogenesis (DO) combined with sliding genioplasty, using skeletal anchorage. CASE PRESENTATION: We first performed interpositional arthroplasty, in which an interposition of fascia temporalis and surrounding fat tissue was inserted into the defect after bilateral condylectomy, increasing the maximum mouth opening from 5...
November 10, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/29125933/can-use-of-rigid-fixation-after-consolidation-benefit-cleft-patients-following-distraction-osteogenesis
#7
Reza Tabrizi, Kemal Tumer, Shervin Shafiei, Ashkan Rashad
PURPOSE: The stability of distraction osteogenesis (DO) is an important issue in maxillary advancement for patients with cleft lip and palate (CLP). The aim of this study was to evaluate postoperative stability in patients with and without internal fixation after removing maxillary distraction devices. MATERIALS AND METHODS: This randomized clinical trial assessed patients with CLP who needed maxillary advancement greater than 6 mm; they were randomly assigned to 1 of 2 groups...
October 16, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29095728/effects-of-local-low-dose-alendronate-injections-into-the-distraction-gap-on-new-bone-formation-and-distraction-rate-on-distraction-osteogenesis
#8
Yunus Emre Alp, Alper Taskaldiran, Mustafa Ercument Onder, Siyami Karahan, Ismail Doruk Kocyigit, Fethi Atil, Umut Tekin
Bisphosphonates that constrain bone resorption have a direct effect on osteoclast function. In this experimental study, the effects of low-dose local alendronate injections on the distraction gap (DG) in rabbit mandible at 2 different rates were evaluated.The experimental study was conducted on 20 male, New Zealand white rabbits. The animals were divided into 3 experimental groups and 1 control group. Group 1 consisted of animals with distraction at the rate of 1 mm/day, receiving postoperative local low-dose alendronate local injections into the DG...
November 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29091962/porcine-brain-extract-promotes-osteogenic-differentiation-of-bone-marrow-derived-mesenchymal-stem-cells-and-bone-consolidation-in-a-rat-distraction-osteogenesis-model
#9
Jia Xu, Yuxin Sun, Tianyi Wu, Bin Wang, Yang Liu, Jinfang Zhang, Wayne Yukwai Lee, Qinglin Kang, Yimin Chai, Gang Li
Distraction osteogenesis (DO) is the gold standard to treat large bone defects, but long consolidation period is a major limitation. Innovative efforts to promote osteogenesis are needed. Porcine brain extract (PBE) was reported to enhance the proliferation and differentiation of multiple primary cells. In this study, we aimed to develop a method for collecting PBE and investigate its effects on osteogenic differentiation of rat bone marrow derived mesenchymal stem cells (rBMSCs) and bone consolidation in a rat DO model...
2017: PloS One
https://www.readbyqxmd.com/read/29084117/a-review-of-randomized-controlled-trials-in-cleft-and-craniofacial-surgery
#10
Jonathan M Bekisz, Elise Fryml, Roberto L Flores
This study presents a systematic review of randomized controlled trials (RCTs) in cleft and craniofacial surgery. All studies reporting on RCTs in cleft and craniofacial surgery were identified on PubMed using the search terms "cleft," "velopharyngeal insufficiency," "velopharyngeal dysfunction," "nasoalveolar molding," "gingivoperiosteoplasty," "Pierre Robin sequence," "craniofacial," "craniosynostosis," "craniofacial microsomia," "hemifacial microsomia," "hypertelorism," "Le Fort," "monobloc," "distraction osteogenesis," "Treacher Collins," and "Goldenhar...
October 27, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29080923/treatment-of-critical-sized-bone-defects-clinical-and-tissue-engineering-perspectives
#11
REVIEW
Erika Roddy, Malcolm R DeBaun, Adam Daoud-Gray, Yunzhi P Yang, Michael J Gardner
Critical-sized bone defects are defined as those that will not heal spontaneously within a patient's lifetime. Current treatment options include vascularized bone grafts, distraction osteogenesis, and the induced membrane technique. The induced membrane technique is an increasingly utilized method with favorable results including high rates of union. Tissue engineering holds promise in the treatment of large bone defects due to advancement of stem cell biology, novel biomaterials, and 3D bioprinting. In this review, we provide an overview of the current operative treatment strategies of critical-sized bone defects as well as the current state of tissue engineering for such defects...
October 28, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29077684/nasopharyngoscopic-analyses-through-anterior-maxillary-distraction-osteogenesis-for-adolescent-patients-with-cleft-palate
#12
Yoshimichi Imai, Tetsu Nakajo, Kazuaki Nishimura, Hiroyuki Kanzaki, Takayoshi Daimaruya, Akimitsu Satoh, Kaoru Igarashi, Masahiro Tachi
Anterior maxillary distraction osteogenesis (AMDO) is a novel technique for correcting hypoplastic maxilla by sagittal expansion of the maxilla. Recent reports suggest that AMDO does not have an effect on fragile velopharyngeal function in patients with cleft palate. Furthermore, no studies have evaluated the impact of AMDO on velopharyngeal function.We adopted AMDO to correct severe hypoplastic maxilla in adolescent patients with cleft palate and evaluated its impact on velopharyngeal space and function in 8 patients aged 12 to 21 years who underwent AMDO from 2006 to 2014...
October 26, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29072495/distraction-osteogenesis-and-fusion-for-failed-first-metatarsophalangeal-joint-replacement-case-series
#13
Rachael J Da Cunha, Sydney C Karnovsky, Austin T Fragomen, Mark C Drakos
No abstract text is available yet for this article.
October 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29072225/bilateral-pediatric-mandibular-distraction-for-micrognathia-with-temporomandibular-joint-ankylosis-and-sleep-apnea
#14
S M Balaji
Mandibular retrognathism is one of the important contributing anatomical factors to the obstructive sleep apnea (OSA). Such patients suffer from number of apneic or hypopneic events during sleep such as snoring, daytime sleepiness, fatigue, inability to concentrate, and irritability. Distraction osteogenesis is a less invasive surgical technique in the management of OSA by correcting the reduced airway space. Apart from correcting functional disturbances due to OSA, it also corrects the facial profile resulting in the substantial improvement in cosmetic appearance...
September 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/29068973/rigid-external-distractor-aided-advancement-after-simultaneously-performed-lefort-iii-osteotomy-and-fronto-orbital-advancement
#15
Ali-Farid Safi, Matthias Kreppel, Martin Kauke, Andrea Grandoch, Hans-Joachim Nickenig, Joachim Zöller
Due to the complex development of the craniofacial skull, corrective surgery is a major challenge for patients with severe craniofaciostenosis. Although fronto-orbital advancement and simultaneous LeFort-III osteotomy in combination with distraction osteogenesis have been reported as a safe and successful method to obtain good esthetic and functional results, there is a lack of studies evaluating this method.Our retrospective study included 12 patients with syndromic craniofaciostenosis, who were primarily treated at our department in accordance with a standardized treatment protocol, consisting of a simultaneous fronto-orbital advancement with LeFort-III osteotomy in combination with a rigid external distractor (RED-II)...
October 24, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29062650/corrected-cephalometric-analysis-to-determine-the-distance-and-vector-of-distraction-osteogenesis-for-syndromic-craniosynostosis
#16
Shinji Kobayashi, Toshihiko Fukawa, Takashi Hirakawa, Toshihiko Satake, Jiro Maegawa
BACKGROUND: The purpose of this study was to confirm the utility of a corrected cephalometric analysis to facilitate the planning of distraction osteogenesis with Le Fort III osteotomy for syndromic craniosynostosis. METHODS: This prospective study involved 4 male and 2 female patients (mean patient age, 8 years 9 months; age range, 4 years 6 months to 13 years 2 months) with Crouzon syndrome who were treated with Le Fort III maxillary distraction using our previously described system of analysis of a corrected cephalogram and who underwent clinical follow-up...
September 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29040144/surgical-treatment-of-dentofacial-deformities-caused-by-juvenile-idiopathic-arthritis
#17
Patricia Stoor, Zlatan Hodzic, Sirpa Arte
The purpose of our retrospective study was to evaluate the results of orthognathic treatment, distraction osteogenesis, and/or prosthetic reconstruction of the temporomandibular joints in patients with juvenile idiopathic arthritis (JIA).Twelve patients with severely affected temporomandibular joints (TMJs) and reduced ramus height were treated with mandibular advancement with orthognathic surgery (11) and additional bilateral or unilateral mandibular ramus distraction (3) or additional bilateral or unilateral prosthetic reconstruction of the TMJ (3)...
October 16, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29030279/posterior-cranial-vault-distraction-osteogenesis-in-craniofacial-surgery-technical-note
#18
Q de Kerangal, A Paré, A Joly, N Travers, D Goga, B Laure
INTRODUCTION: Posterior cranial vault distraction is a treatment for intracranial hypertension in certain cases of craniosynostosis and faciocraniosynostosis. It allows the harmonization of the skull back and prevents turricephaly. This study presents the surgical technique. TECHNICAL NOTE: Posterior cranial vault distraction osteogenesis consists of a circular osteotomy of the skull back. Four distractors are placed on the cranial flap without detachment of the dura mater...
October 10, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29026807/airway-management-in-pierre-robin-sequence-the-vancouver-classification
#19
Wai-Yee Li, Alana Poon, Douglas Courtemanche, Cynthia Verchere, Sandra Robertson, Marija Bucevska, Claudia Malic, Jugpal S Arneja
BACKGROUND: Pierre Robin sequence (PRS) is a triad of micrognathia, glossoptosis, and respiratory distress. There is no standard clinical classification used in the management of neonatal airway in patients with PRS. The goal of our study was to review the presentation and management of patients with PRS and formulate a clinical grading system and treatment algorithm. METHODS: A 10-year retrospective review of all neonates diagnosed with PRS was performed after obtaining institutional ethics approval...
February 2017: Plastic Surgery
https://www.readbyqxmd.com/read/28968331/reconstruction-of-mandibular-segmental-detects-using-transport-disk-distraction-osteogenesis
#20
Tao Li, Yi Man, Ruiye Bi, Nan Jiang, Yunfeng Li, Songsong Zhu
BACKGROUND: Distraction osteogenesis (DO) has become an important alternative for bone defect reconstruction. The study aims to investigate the clinical feasibility and efficiency of transport disc DO (TDDO) for reconstruction of segmental defect of mandible and further dental implant treatment. METHODS: A serial of 6 patients diagnosed with ameloblastoma or keratocystic odontogenic tumor were included in this study. Computed tomography (CT) scanning and panoramic radiograph were performed for preoperative evaluation and surgery planning...
November 2017: Journal of Craniofacial Surgery
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