keyword
MENU ▼
Read by QxMD icon Read
search

Distraction osteogenesis

keyword
https://www.readbyqxmd.com/read/29352347/autologous-cell-based-therapy-for-treatment-of-large-bone-defects-from-bench-to-bedside
#1
REVIEW
R Verboket, M Leiblein, C Seebach, C Nau, M Janko, M Bellen, H Bönig, D Henrich, I Marzi
OBJECTIVES: Reconstruction of long segmental bone defects is demanding for patients and surgeons, and associated with long-term treatment periods and substantial complication rates in addition to high costs. While defects up to 4-5 cm length might be filled up with autologous bone graft, heterologous bone from cadavers, or artificial bone graft substitutes, current options to reconstruct bone defects greater than 5 cm consist of either vascularized free bone transfers, the Masquelet technique or the Ilizarov distraction osteogenesis...
January 19, 2018: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/29351034/postoperative-complications-following-lefort-1-maxillary-advancement-surgery-in-cleft-palate-patients-a-5-year-retrospective-study
#2
Isabelle Moran, Satnam Virdee, Ian Sharp, Jagdeep Sulh
OBJECTIVE: To investigate the postoperative complication rates of LeFort 1 maxillary advancement surgery in cleft patients when performed by a single surgeon over a 5-year period. DESIGN: A retrospective case note review of 79 cleft palate patients. SETTING: All surgery was performed by a single oral and maxillofacial surgeon in a tertiary care center. PARTICIPANTS: All cleft palate patients over 17 years of age who opted for surgical correction of maxillary hypoplasia with a LeFort 1 between 2010 and 2015...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29303863/unusual-craniofacial-distraction
#3
Aina V H Greig, Court B Cutting, Jamie Levine, Barry Grayson, Joseph G McCarthy
A retrospective Institutional Review Board-approved review was performed at the Institute of Reconstructive Plastic Surgery, NYU Langone Medical Center, of patients undergoing craniofacial distraction osteogenesis procedures using the rigid external distractor device between 2000 and 2010. Three particularly challenging cases were identified and are presented here.
January 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29303852/interpositional-arthroplasty-by-temporalis-fascia-flap-and-galea-aponeurotica-combined-with-distraction-osteogenesis-a-modified-method-in-treatment-of-adult-patients-with-temporomandibular-joint-ankylosis-and-mandibular-dysplasia
#4
Jia Qiao, Bing Yu, Lai Gui, Xi Fu, Chung-Kwan Yen, Feng Niu, Huijun Zhang, Cai Wang, Ying Chen, Meng Wang, Jianfeng Liu
BACKGROUND: Interpositional arthroplasty (IPA) with temporalis fascia flap has been one of the most frequently performed procedures to treat temporomandibular joint (TMJ) ankylosis. However, recurrence often occurs when the flap lacks bulk or atrophies. Whether to perform IPA or distraction osteogenesis (DO) first has long been a controversial issue when patients presented mandibular dysplasia (MD). This study provided IPA a new graft material sufficient to prevent recurrence, combined the modified protocol of performing DO 6 months after IPA, and evaluated its efficacy in treating TMJ ankylosis patients with MD...
January 4, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29274310/is-bone-morphogenetic-protein-2-as-effective-as-alveolar-distraction-osteogenesis-for-vertical-bone-regeneration
#5
Jose M Reuss, Joan Pi-Anfruns, Peter K Moy
PURPOSE: The aim of this study was to assess the clinical effectiveness of alveolar distraction osteogenesis (ADO) versus recombinant human bone morphogenetic protein-2 (rh-BMP-2) for vertical ridge augmentation. Few data have been published on vertical bone regeneration using rh-BMP-2. MATERIALS AND METHODS: The authors implemented a retrospective cohort study and enrolled a sample composed of patients with deficient alveolar vertical bone height. The primary predictor variable was vertical augmentation with BMP-2 and a titanium mesh or ADO...
November 29, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29228043/novel-systems-for-the-application-of-isolated-tensile-compressive-and-shearing-stimulation-of-distraction-callus-tissue
#6
Nicholaus Meyers, Julian Schülke, Anita Ignatius, Lutz Claes
BACKGROUND: Distraction osteogenesis is a procedure widely used for the correction of large bone defects. However, a high complication rate persists, likely due to insufficient stability during maturation. Numerical fracture healing models predict bone regeneration under different mechanical conditions allowing fixation stiffness optimization. However, most models apply a linear elastic material law inappropriate for the transient stresses/strains present during limb lengthening or segment transport...
2017: PloS One
https://www.readbyqxmd.com/read/29194272/comparison-of-complication-rate-between-lefort-iii-and-monobloc-advancement-with-or-without-distraction-osteogenesis
#7
Rebecca Knackstedt, Bahar Bassiri Gharb, Frank Papay, Antonio Rampazzo
BACKGROUND: LeFort III osteotomies or monobloc advancements, with or without distraction, can be used to treat mid-facial hypoplasia causing exorbitism and obstructive sleep apnea in syndromic patients. This report is a meta-analysis of the complication rates following LeFort III osteotomies or monobloc advancement with or without distraction. METHODS: Triple database search was conducted to identify articles addressing mid-facial hypoplasia treated with LeFort III or monobloc in which complications were detailed...
November 20, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29194258/management-of-nonsyndromic-skeletal-dysgnathia-by-distraction-osteogenesis-long-term-follow-up
#8
Gagan Deep Kochar, Ashish Chakranarayan, Bensy Varghese, Sanjay Manohar Londhe, Sanjay Kumar Roy Chowdhury, Shreehari Ambika Krishnawarrier
Distraction osteogenesis has been a paradigm shift in the field of orthognathic surgery. Majority of the published cases are those of syndromic patients that have been managed using varying treatment protocols. This communication describes a patient of 18-year-old male diagnosed with skeletal Class II malocclusion due to mandibular retognathism. The patient was taken up for mandibular corpus distraction of 10 mm. By this approach the patient was benefitted with good esthetic result and functional occlusion...
November 29, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29184744/multidirectional-cranial-distraction-osteogenesis-with-simplified-modifications-for-treating-sagittal-synostosis
#9
Ataru Sunaga, Yasushi Sugawara, Hideaki Kamochi, Akira Gomi, Daekwan Chi, Rintaro Asahi, Masanori Mori, Shunji Sarukawa, Hirokazu Uda, Kotaro Yoshimura
Background: Multidirectional cranial distraction osteogenesis (MCDO) is a procedure of ours developed earlier for treating craniosynostosis. However, the numerous bone flaps led to prolonged operative time and occasional bone detachment from dura. We have since simplified the osteotomy design. In treating sagittal synostosis, required bone flaps have been reduced to 11 (from ~20). Methods: In a 2-year period (2014-2015), 5 boys with sagittal synostosis underwent MCDO using our simplified and fixed-form osteotomy...
October 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29178906/femoral-nonunion-with-segmental-bone-defect-treated-by-distraction-osteogenesis-with-monolateral-external-fixation
#10
Qun Zhang, Wei Zhang, Zhuo Zhang, Licheng Zhang, Hua Chen, Ming Hao, Junhao Deng, Peifu Tang
BACKGROUND: Currently, the common treatment for femoral nonunion with large segmental bone defect is difficult and complex. The effective surgical methods are rare, include vascularized bone grafting, Masquelet technique and Ilizarov distraction osteogenesis. The objective of this study is to investigate the outcomes of segmental femoral defects treated with monolateral external fixation using the distraction osteogenesis. METHODS: We retrospectively analyzed patients with femoral nonunion with segmental bone defects (> 6 cm) between January 2010 and January 2014 in our single trauma center...
November 25, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29163798/microrna-144-3p-inhibits-bone-formation-in-distraction-osteogenesis-through-targeting-connexin-43
#11
Yu-Xin Sun, Jin-Fang Zhang, Jia Xu, Liang-Liang Xu, Tian-Yi Wu, Bin Wang, Xiao-Hua Pan, Gang Li
Distraction osteogenesis (DO), one of effective therapies for bone regeneration, has been received more attention in recent years. However, the underlying mechanism remains elusive. Recently, microRNAs (miRNAs) have been reported to play important roles in regulating osteogenesis and bone formation. We therefore provided the hypothesis that miRNAs could involve in the DO-mediated bone regeneration. After successfully established the DO model of rats, a miRNA microarray was performed to find the differently expressed miRNAs in DO and control groups in this study...
October 27, 2017: Oncotarget
https://www.readbyqxmd.com/read/29155725/an-efficient-and-reproducible-protocol-for-distraction-osteogenesis-in-a-rat-model-leading-to-a-functional-regenerated-femur
#12
Martine Pithioux, Flavy Roseren, Christian Jalain, Franck Launay, Philippe Charpiot, Patrick Chabrand, Sandrine Roffino, Edouard Lamy
This protocol describes the use of a newly developed external fixator for distraction osteogenesis in a rat femoral model. Distraction osteogenesis (DO) is a surgical technique leading to bone regeneration after an osteotomy. The osteotomized extremities are moved away from each other by gradual distraction to reach the desired elongation. This procedure is widely used in humans for lower and upper limb lengthening, treatment after a bone nonunion, or the regeneration of a bone defect following surgery for bone tumor excision, as well as in maxillofacial reconstruction...
October 23, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29153233/temporomandibular-joint-reconstruction-in-the-growing-child
#13
REVIEW
Cory M Resnick
Indications and considerations for reconstruction of the temporomandibular joint (TMJ) differ between growing and skeletally mature patients. Osteoarthritis, which is the most common cause of TMJ destruction in adults, is comparatively rare in children. The most common indications in young patients are congenital deformities, pathology, ankylosis and progressive resorptive processes. Options for reconstruction include distraction osteogenesis, autologous reconstruction (ie, costochondral graft, free fibula flap), and total alloplastic joint replacement...
February 2018: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/29142868/protrusive-maxillomandibular-fixation-for-intracapsular-condylar-fracture-a-report-of-two-cases
#14
Yeong Kon Jeong, Won-Jong Park, Il Kyung Park, Gi Tae Kim, Eun Joo Choi
Clinical limitations following closed reduction of an intracapsular condylar fracture include a decrease in maximum mouth opening, reduced range of mandibular movements such as protrusion/lateral excursion, and reduced occlusal stability. Anteromedial and inferior displacement of the medial condyle fragment by traction of the lateral pterygoid muscle can induce bone overgrowth due to distraction osteogenesis between the medial and lateral condylar fragments, causing structural changes in the condyle. In addition, when conventional maxillomandibular fixation (MMF) is performed, persistent interdental contact sustains masticatory muscle hyperactivity, leading to a decreased vertical dimension and premature contact of the posterior teeth...
October 2017: Journal of the Korean Association of Oral and Maxillofacial Surgeons
https://www.readbyqxmd.com/read/29135733/treatment-of-maxillary-hypoplasia-in-cleft-lip-and-palate-segmental-distraction-osteogenesis-with-hyrax-device
#15
Rodrigo Fariña, Alejandro Diaz, Roberto Pantoja, Carolina Bidart
The objective of this work is to describe a segmental maxillary distraction osteogenesis (SDO) with segmental Lefort I with an inexpensive device.Four patients who presented severe class III and maxillary hypoplasia due to cleft lip and palate sequel were treated. A SDO was performed using a dental-anchored Hyrax device, achieving enlargement of the upper jaw without altering speech, with adequate and stable occlusion. Dental implants in a new formed bone were installed.The authors can conclude that SDO is a good treatment alternative for patients with maxillary hypoplasia...
November 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29126770/effects-of-unilateral-vertical-mandibular-distraction-osteogenesis-on-airway-anatomy-in-children-with-hemifacial-microsomia
#16
Navid Pourtaheri, Derek Z Wang, Srinivas M Susarla, Gerhard S Mundinger, Anand R Kumar
PURPOSE: To assess the two- and three-dimensional airway changes following unilateral vertical mandibular distraction osteogenesis (vMDO) in patients with hemifacial microsomia (HFM). METHODS: A retrospective evaluation was performed for consecutive patients over an 18-month period with HFM and with Kaban-Pruzansky Type-II mandibular deformities who underwent unilateral vMDO for correction of vertical mandibular asymmetry. Patients with complete records and a minimum of 12 months of clinical follow-up post-consolidation were included...
October 13, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29126455/micrognathia-with-temporomandibular-joint-ankylosis-and-obstructive-sleep-apnea-treated-with-mandibular-distraction-osteogenesis-using-skeletal-anchorage-a-case-report
#17
Hiroshi Tomonari, Hiroko Takada, Tomofumi Hamada, Sangho Kwon, Tsuyoshi Sugiura, Shouichi Miyawaki
BACKGROUND: We describe the case of a 16-year-old female patient with micrognathia, temporomandibular joint (TMJ) ankylosis, and obstructive sleep apnea, who was treated with mandibular distraction osteogenesis (DO) combined with sliding genioplasty, using skeletal anchorage. CASE PRESENTATION: We first performed interpositional arthroplasty, in which an interposition of fascia temporalis and surrounding fat tissue was inserted into the defect after bilateral condylectomy, increasing the maximum mouth opening from 5...
November 10, 2017: Head & Face Medicine
https://www.readbyqxmd.com/read/29125933/can-use-of-rigid-fixation-after-consolidation-benefit-cleft-patients-following-distraction-osteogenesis
#18
Reza Tabrizi, Kemal Tumer, Shervin Shafiei, Ashkan Rashad
PURPOSE: The stability of distraction osteogenesis (DO) is an important issue in maxillary advancement for patients with cleft lip and palate (CLP). The aim of this study was to evaluate postoperative stability in patients with and without internal fixation after removing maxillary distraction devices. MATERIALS AND METHODS: This randomized clinical trial assessed patients with CLP who needed maxillary advancement greater than 6 mm; they were randomly assigned to 1 of 2 groups...
October 16, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29095728/effects-of-local-low-dose-alendronate-injections-into-the-distraction-gap-on-new-bone-formation-and-distraction-rate-on-distraction-osteogenesis
#19
Yunus Emre Alp, Alper Taskaldiran, Mustafa Ercument Onder, Siyami Karahan, Ismail Doruk Kocyigit, Fethi Atil, Umut Tekin
Bisphosphonates that constrain bone resorption have a direct effect on osteoclast function. In this experimental study, the effects of low-dose local alendronate injections on the distraction gap (DG) in rabbit mandible at 2 different rates were evaluated.The experimental study was conducted on 20 male, New Zealand white rabbits. The animals were divided into 3 experimental groups and 1 control group. Group 1 consisted of animals with distraction at the rate of 1 mm/day, receiving postoperative local low-dose alendronate local injections into the DG...
November 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29091962/porcine-brain-extract-promotes-osteogenic-differentiation-of-bone-marrow-derived-mesenchymal-stem-cells-and-bone-consolidation-in-a-rat-distraction-osteogenesis-model
#20
Jia Xu, Yuxin Sun, Tianyi Wu, Bin Wang, Yang Liu, Jinfang Zhang, Wayne Yukwai Lee, Qinglin Kang, Yimin Chai, Gang Li
Distraction osteogenesis (DO) is the gold standard to treat large bone defects, but long consolidation period is a major limitation. Innovative efforts to promote osteogenesis are needed. Porcine brain extract (PBE) was reported to enhance the proliferation and differentiation of multiple primary cells. In this study, we aimed to develop a method for collecting PBE and investigate its effects on osteogenic differentiation of rat bone marrow derived mesenchymal stem cells (rBMSCs) and bone consolidation in a rat DO model...
2017: PloS One
keyword
keyword
51074
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"