keyword
MENU ▼
Read by QxMD icon Read
search

Fluid retention

keyword
https://www.readbyqxmd.com/read/28446278/-clinical-analysis-for-42-imatinib-resistant-patients-with-chronic-myelogenous-leukemia
#1
Xi Liu, Si-Lin Gan, Jie Ma, Yan-Fang Liu, Xin-Sheng Xie, Zhong-Xing Jiang, Yuan-Dong Cheng, Hui Sun
OBJECTIVE: To analyze the kinase mutation ratio, related factors, effectiveness and safety of the second generation drugs for imatinib-resistant patients with chronic myeloid leukemia(CML). METHODS: COX proportional hazard regression model was used for unvariate and multvariate analysis of various factors affecting the kinase mutation and for evaluating the effectiveness and safety of second generation tyrosine kinase inhibitor(TKI). RESULTS: 13 kinds of mutation were detected in 19 out of 42 cases for 22 times, including 4 times of F359V, 3 times of E255K, 2 time for F359C, F317L, T315I, Y253H, 1 time for D256R, C250R, D276G, F486S, M244V, Y256H and G250E, 3 cases with mixed mutations...
April 2017: Zhongguo Shi Yan Xue Ye Xue za Zhi
https://www.readbyqxmd.com/read/28442951/renal-water-conservation-determines-the-increase-in-body-weight-after-surgery-a-randomized-controlled-trial
#2
Robert G Hahn
BACKGROUND: The present study was undertaken to identify factors that correlate with the gain in body weight after surgery. METHODS: Twenty-one patients (median age of 49 years) were randomized to receive either Ringer × s acetate or 6% dextran 70 as their first infusion fluid during cholecystectomy or hysterectomy. Each patient's body weight was measured before the surgery and on the first postoperative morning. Blood and urine samples were analyzed for signs of stress, inflammation, and kidney injury...
April 2017: Saudi Journal of Anaesthesia
https://www.readbyqxmd.com/read/28441967/comparison-of-csf-markers-and-semi-quantitative-amyloid-pet-in-alzheimer-s-disease-diagnosis-and-in-cognitive-impairment-prognosis-using-the-adni-2-database
#3
Fayçal Ben Bouallègue, Denis Mariano-Goulart, Pierre Payoux
BACKGROUND: The relative performance of semi-quantitative amyloid positron emission tomography (PET) and cerebrospinal fluid (CSF) markers in diagnosing Alzheimer's disease (AD) and predicting the cognitive evolution of patients with mild cognitive impairment (MCI) is still debated. METHODS: Subjects from the Alzheimer's Disease Neuroimaging Initiative 2 with complete baseline cognitive assessment (Mini Mental State Examination, Clinical Dementia Rating [CDR] and Alzheimer's Disease Assessment Scale-Cognitive Subscale [ADAS-cog] scores), CSF collection (amyloid-β1-42 [Aβ], tau and phosphorylated tau) and (18)F-florbetapir scans were included in our cross-sectional cohort...
April 26, 2017: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/28440691/n-butyl-2-cyanoacrylate-based-injectable-and-in-situ-forming-implants-for-efficient-intratumoral-chemotherapy
#4
Yanpu Wu, Luming Wang, Kaili Zhang, Lixiao Zhou, Xiaobing Zhang, Xuecheng Jiang, Chenggang Zhu
The local delivery of chemotherapeutic drugs to tumor sites is an effective approach for achieving therapeutic drug concentrations in solid tumors. Injectable implants with the ability to form in situ represent one of the most promising technologies for intratumoral chemotherapy. However, many issues must be resolved before these implants can be applied in clinical practice. Herein, we report a novel injectable in situ-forming implant system composed of n-butyl-2-cyanoacrylate (NBCA) and ethyl oleate, and the sol-gel phase transition is activated by anions in body fluids or blood...
November 2017: Drug Delivery
https://www.readbyqxmd.com/read/28436969/associations-between-levels-of-insulin-like-growth-factor-1-and-sinusoidal-obstruction-syndrome-after-allogeneic-haematopoietic-stem-cell-transplantation
#5
S Weischendorff, K Kielsen, H Sengeløv, K Jordan, C H Nielsen, A E Pedersen, L P Ryder, A Juul, K G Müller
Allogeneic myeloablative haematopoietic stem cell transplantation (HSCT) is challenged by severe adverse events, as cytotoxic effects of the conditioning may result in systemic inflammation, leaky epithelial barriers and organ toxicities, contributing to treatment-related morbidity and mortality. We hypothesised that insulin-like growth factor-1 (IGF-1), a mediator of growth and proliferation of various tissues, may attenuate chemotherapy-induced tissue damage after HSCT. We prospectively measured plasma levels of IGF-1 and its binding protein 3 (IGFBP-3) in 41 patients undergoing myeloablative HSCT...
April 24, 2017: Bone Marrow Transplantation
https://www.readbyqxmd.com/read/28436118/enantioselective-potential-of-polysaccharide-based-chiral-stationary-phases-in-supercritical-fluid-chromatography
#6
Gabriela Kucerova, Kveta Kalikova, Eva Tesarova
The enantioselective potential of two polysaccharide-based chiral stationary phases for analysis of chiral structurally diverse biologically active compounds was evaluated in supercritical fluid chromatography using a set of 52 analytes. The chiral selectors immobilized on 2.5 μm silica particles were tris-(3,5-dimethylphenylcarmabate) derivatives of cellulose or amylose. The influence of the polysaccharide backbone, different organic modifiers, and different mobile phase additives on retention and enantioseparation was monitored...
April 24, 2017: Chirality
https://www.readbyqxmd.com/read/28435930/spinal-subdural-hematoma-a-rare-case-of-spinal-subdural-hematoma-complicating-routine-minimally-invasive-lumbar-discectomy-and-decompression-and-relevant-literature-review
#7
Chelsea C Boe, Brett A Freedman, Ravi Kumar, Kendall Lee, Robert McDonald, John Port
We present a case of apparently uncomplicated lumbar decompression and discectomy with delayed postoperative neurological deterioration secondary to subdural hematoma at the thoracolumbar level of the spinal cord. Previously described subdural hematomas have occurred spontaneously or related to iatrogenic injury. Hitherto, no case of acute postoperative subdural hematoma has been reported in the postoperative setting in the absence of known iatrogenic dural injury. A 76-year-old male with central and lateral recess spinal stenosis underwent apparently uncomplicated bilateral L3-4 and left sided L4-5 decompressive partial laminectomies and discectomy...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28434714/speed-resolution-advantage-of-turbulent-supercritical-fluid-chromatography-in-open-tubular-columns-ii-theoretical-and-experimental-evidences
#8
Fabrice Gritti, Michael Fogwill
The potential advantage of turbulent supercritical fluid chromatography (TSFC) in open tubular columns (OTC) was evaluated on both theoretical and practical viewpoints. First, the dispersion model derived by Golay in 1958 and recently extended from laminar to turbulent flow regime is used for the predictions of the speed-resolution performance in TSFC. The average dispersion coefficient of matter in the turbulent flow regime was taken from the available experimental data over a range of Reynolds number from 2000 to 6000...
April 19, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28433764/modeling-of-retention-and-re-entrainment-of-mono-and-poly-disperse-particles-effects-of-hydrodynamics-particle-size-and-interplay-of-different-sized-particles-retention
#9
Enze Ma, Tariq Ouahbi, Huaqing Wang, Nasre-Dine Ahfir, Abdellah Alem, Ahmed Hammadi
In this paper, numerical simulations of experimental data were performed with kinetic rate coefficients to characterize the retention and re-entrainment dynamics under different hydrodynamic conditions for monodisperse and polydisperse latex particles (3, 10, 16μm and the mixture). The results show that drastic increase in fluid velocity provokes hardly any remarkable decrease in retention in the presence of large energy barriers (>2000kT). Systematical increases in deposition and re-entrainment dynamic rates were observed with fluid velocity and/or particle size...
April 20, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28422383/liquid-and-subcritical-fluid-chromatographic-enantioseparation-of-n-%C3%AE-fmoc-proteinogenic-amino-acids-on-quinidine-based-zwitterionic-and-anion-exchanger-type-chiral-stationary-phases-a-comparative-study
#10
Gyula Lajkó, Nóra Grecsó, Gábor Tóth, Ferenc Fülöp, Wolfgang Lindner, István Ilisz, Antal Péter
Stereoselective high-performance liquid chromatographic and subcritical fluid chromatographic separations of 19 N(α) -Fmoc proteinogenic amino acid enantiomers were carried out by using Quinidine-based zwitterionic and anion-exchanger-type chiral stationary phases Chiralpak ZWIX(-) and QD-AX. For optimization of retention and enantioselectivity, the ratio of bulk solvent components (MeOH/MeCN, H2 O/MeOH, or CO2 /MeOH) and the nature and concentration of the acid and base additives (counter- and co-ions) were systematically varied...
April 19, 2017: Chirality
https://www.readbyqxmd.com/read/28420330/anti-mog-antibody-positive-adem-following-infectious-mononucleosis-due-to-a-primary-ebv-infection-a-case-report
#11
Yoshitsugu Nakamura, Hideto Nakajima, Hiroki Tani, Takafumi Hosokawa, Shimon Ishida, Fumiharu Kimura, Kimihiko Kaneko, Toshiyuki Takahashi, Ichiro Nakashima
BACKGROUND: Anti-Myelin oligodendrocyte glycoprotein (MOG) antibodies are detected in various demyelinating diseases, such as pediatric acute disseminated encephalomyelitis (ADEM), recurrent optic neuritis, and aquaporin-4 antibody-seronegative neuromyelitis optica spectrum disorder. We present a patient who developed anti-MOG antibody-positive ADEM following infectious mononucleosis (IM) due to Epstein-Barr virus (EBV) infection. CASE PRESENTATION: A 36-year-old healthy man developed paresthesia of bilateral lower extremities and urinary retention 8 days after the onset of IM due to primary EBV infection...
April 19, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28404372/enantioseparation-of-novel-chiral-sulfoxides-on-chlorinated-polysaccharide-stationary-phases-in-supercritical-fluid-chromatography
#12
Caroline West, Mari-Luiza Konjaria, Natia Shashviashvili, Elise Lemasson, Pascal Bonnet, Rusudan Kakava, Alessandro Volonterio, Bezhan Chankvetadze
Asymmetric sulfoxides is a particular case of chirality that may be found in natural as well as synthetic products. Twenty-four original molecules containing a sulfur atom as a centre of chirality were analyzed in supercritical fluid chromatography on seven polysaccharide-based chiral stationary phases (CSP) with carbon dioxide - methanol mobile phases. While all the tested CSP provided enantioseparation for a large part of the racemates, chlorinated cellulosic phases proved to be both highly retentive and highly enantioselective towards these species...
April 4, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28403599/renal-extracapsular-hypoechoic-rim-and-kidney-cortical-thickness
#13
Simone Brardi, Gabriele Cevenini, Roberto Ponchietti, Giuseppe Romano, Ennio Duranti
OBJECTIVES: A renal extracapsular hypoechoic rim was previously recognized and interpreted as a typical sonographic finding of renal failure. Subsequently it was hypothesized that the hypoechoic rim could be produced by a state of sodium retention and oedema caused by nephropathy but not necessarily associated with renal failure. In order to get this cleared we performed a retrospective analysis of 80 renal ultrasound examinations, carried out at our center, in 41 of which it was found a renal extracapsular hypoechoic rim...
March 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28390283/chemometrics-enhanced-one-dimensional-comprehensive-two-dimensional-gas-chromatographic-analysis-for-bioactive-terpenoids-and-phthalides-in-chaihu-shugan-san-essential-oils
#14
Min He, Zhi-Yu Yang, Tian-Biao Yang, Ying Ye, Juan Nie, Yong Hu, Pan Yan
Chemometrics-enhanced one-dimensional/comprehensive two-dimensional gas chromatographic (GC/GC×GC) technologies, were used to explore the compositions of Chaihu Shugan San essential oils, that were extracted from the herbal formulae by different schemes. We have shown that chemometric resolution using gas chromatographic- mass spectrometry (GC-MS) could be used for the qualitative and quantitative analysis of the majority of Terpenoids or Phthalides from herb formulae and single herbs. A GC×GC system was further optimized to achieve the increased peak capacity and the enhanced signal of the hydro-distillation sample (CSSh)...
March 30, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28389600/intravascular-donor-monocytes-play-a-central-role-in-lung-transplant-ischaemia-reperfusion-injury
#15
Kate Colette Tatham, Kieran Patrick O'Dea, Rosalba Romano, Hannah Elizabeth Donaldson, Kenji Wakabayashi, Brijesh Vipin Patel, Louit Thakuria, Andre Rudiger Simon, Padmini Sarathchandra, Nandor Marczin, Masao Takata
RATIONALE: Primary graft dysfunction in lung transplant recipients derives from the initial, largely leukocyte-dependent, ischaemia-reperfusion injury. Intravascular lung-marginated monocytes have been shown to play key roles in experimental acute lung injury, but their contribution to lung ischaemia-reperfusion injury post transplantation is unknown. OBJECTIVE: To define the role of donor intravascular monocytes in lung transplant-related acute lung injury and primary graft dysfunction...
April 7, 2017: Thorax
https://www.readbyqxmd.com/read/28389095/chemometric-evaluation-of-the-combined-effect-of-temperature-pressure-and-co-solvent-fractions-on-the-chiral-separation-of-basic-pharmaceuticals-using-actual-vs-set-operational-conditions
#16
Erik Forss, Dan Haupt, Olle Stålberg, Martin Enmark, Jörgen Samuelsson, Torgny Fornstedt
The need to determine the actual operational conditions, instead of merely using the set operational conditions, was investigated for in packed supercritical fluid chromatography (SFC) by design of experiments (DoE) using a most important type of compounds, pharmaceutical basics, as models. The actual values of temperature, pressure, and methanol levels were recorded and calculated from external sensors, while the responses in the DoE were the retention factors and selectivity. A Kromasil CelluCoat column was used as the stationary phase, carbon dioxide containing varying methanol contents as the mobile phase, and the six racemates of alprenolol, atenolol, metoprolol, propranolol, clenbuterol, and mianserin were selected as model solutes...
March 28, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28382959/treatment-of-primary-aldosteronism-is-associated-with-a-reduction-in-the-severity-of-obstructive-sleep-apnoea
#17
M J Wolley, E Pimenta, D Calhoun, R D Gordon, D Cowley, M Stowasser
Obstructive sleep apnoea (OSA) is known to commonly co-exist with primary aldosteronism (PA), but it is unknown if treatment of PA improves sleep apnoea parameters in these patients. We therefore aimed to determine whether specific medical or surgical treatment of PA improves OSA, as measured by the apnoea-hypopnoea index (AHI). We recruited patients undergoing diagnostic workup for PA if they had symptoms suggestive of OSA. Patients with confirmed PA underwent polysomnography (PSG) at baseline and again at least 3 months after specific treatment for PA...
April 6, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28372206/entrapment-of-protein-in-chitosan-tripolyphosphate-beads-and-its-release-in-an-in-vitro-digestive-model
#18
Dongdong Yuan, Jean Christophe Jacquier, E Dolores O'Riordan
This research sought to evaluate the entrapment and in vitro release behaviour of bovine serum albumin (BSA) in chitosan-tripolyphosphate (TPP) hydrogel beads. Beads were manufactured by extruding gel forming solutions containing varying concentrations of chitosan (1-2.5%w/w) and BSA (0.25-10%w/w) into TPP solutions ranging in concentration from 0.1 to 10%w/w and in ionic strength from 0.16 to 0.67M at pH values of 4, 5 and 9.4. Beads produced at a low TPP concentration of 0.4% w/w had the highest BSA entrapment efficiency (71...
August 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28367258/rational-vehicle-design-ensures-targeted-cutaneous-steroid-delivery
#19
Leon Kircik, Franklin Okumu, Sateesh Kandavilli, Jeffrey Sugarman
Objective: To design a topical vehicle that provided the optimal balance of betamethasone dipropionate penetration and retention in the skin, with minimal systemic absorption. Design: Six test formulations of betamethasone dipropionate 0.05% in vehicles contained the following penetration enhancers: elaidyl alcohol (Formulation-1), hexanol (Formulation-2), dodecanol (Formulation-3), octadecanol (Formulation-4), docosanol (Formulation-5), or oleyl alcohol (Formulation-6). Test agents were applied to human cadaver skin in static Franz-cell chambers containing receptor fluid...
February 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28366564/systematic-investigations-of-peak-deformations-due-to-co-solvent-adsorption-in-preparative-supercritical-fluid-chromatography
#20
Emelie Glenne, Hanna Leek, Magnus Klarqvist, Jörgen Samuelsson, Torgny Fornstedt
Strangely shaped overloaded bands were recently reported using a standard supercritical fluid chromatographic system comprising a diol column as the stationary phase and carbon dioxide with methanol as the mobile phase. Some of these overloaded elution profiles appeared strongly deformed and even had "anti-Langmuirian" shapes although their solute compounds had "Langmuirian" adsorption. To obtain a more complete understanding of the generality of these effects, the investigation was expanded to cover also other common co-solvents, such as ethanol, 2-propanol, and acetonitrile, as well as various stationary phase materials, such as silica, and 2-ethylpyridine...
March 22, 2017: Journal of Chromatography. A
keyword
keyword
5107
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"