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magnesium sulphate

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https://www.readbyqxmd.com/read/28782324/congenital-perisylvian-syndrome-presenting-as-post-partum-seizures-with-preeclampsia
#1
Arun Agarwal, Manju Goyal, Jainendra Jain, Aakanksha Agarwal
Whether preceded by preeclampsia, or occuring without antecedent warning symptoms, eclamptic seizures usually occur in the antepartum period between 20 and 40 weeks of gestation or within a few hours to 2 days postpartum. We report the case of a patient with pre-eclampsia who developed seizures after more than 2 days of delivery. In view of late onset postpartum seizures and non-responsiveness to magnesium sulphate, she was further evaluated and diagnosed to have congenital perisylvian syndrome(CPS). In CPS, polymicrogyric cortex is distributed in variable extensions around the sylvian fissure i...
June 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28714170/safety-and-efficacy-of-low-dose-intramuscular-magnesium-sulphate-mgso4-compared-to-intravenous-regimen-for-treatment-of-eclampsia
#2
Pradip Kumar Saha, Jasbinder Kaur, Poonam Goel, Shalija Kataria, Rimpy Tandon, Lekha Saha
AIM: This study was performed to compare the safety and efficacy of low dose intramuscular magnesium sulphate (MgSO4) (Dhaka regimen) and intravenous (IV) MgSO4 (Zuspan regimen) for the prevention of eclampsia recurrence and to compare serum magnesium concentration. METHODS: Forty one eligible patients with eclampsia were randomly divided into two groups: group I patients received IV MgSO4 according to the Zuspan regime, while group II patients received intramuscular (IM) MgSO4 according to the Dhaka regimen (i...
July 16, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28708577/a-one-year-review-of-eclampsia-in-an-ethiopian-tertiary-care-center-saint-paul-s-hospital-millennium-medical-college-sphmmc
#3
Thomas Mekuria, Abdulfetah Abdosh
Eclampsia remains one of the five major causes of maternal mortality in developing countries. Advances in diagnosis and management have led to a significant reduction in maternal mortality and morbidity from this disease in developed countries. In developing countries the incidence of maternal death attributed to eclampsia remains high and, in Ethiopia, maternal mortality from this complication has instead risen over the last decade. The purpose of this study was to review the incidence of eclampsia at the largest feto-maternal center in the country over 1 year in an attempt to determine what quality improvement measures are needed and could realistically be implemented within the system to decrease this complication...
July 14, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28669072/free-and-immobilized-aspergillus-oryzae-sbs50-producing-protease-resistant-and-thermostable-phytase
#4
Sapna, Bijender Singh
Optimization for enhanced phytase production by Aspergillus oryzae SBS50 in submerged fermentation was investigated using Taguchi design. In first step design, starch, beef extract, magnesium sulphate, ferrous sulphate and Tween 80 were identified as significant factors affecting phytase production. These significant factors were further optimized at four different levels using a second Taguchi design and were observed that 1% starch, 2% beef extact, 3% Tween 80, 0.1% magnesium sulphate and 0.225% ferrous sulphate supported maximum phytase production (47,432 U/L)...
July 2017: 3 Biotech
https://www.readbyqxmd.com/read/28662068/effects-of-anabolic-and-catabolic-nutrients-on-woody-plant-encroachment-after-long-term-experimental-fertilization-in-a-south-african-savanna
#5
Anthony J Mills, Antoni V Milewski, Dirk Snyman, Jorrie J Jordaan
The causes of the worldwide problem of encroachment of woody plants into grassy vegetation are elusive. The effects of soil nutrients on competition between herbaceous and woody plants in various landscapes are particularly poorly understood. A long-term experiment of 60 plots in a South African savanna, comprising annual applications of ammonium sulphate (146-1166 kg ha-1 yr-1) and superphosphate (233-466 kg ha-1 yr-1) over three decades, and subsequent passive protection over another three decades, during which indigenous trees encroached on different plots to extremely variable degrees, provided an opportunity to investigate relationships between soil properties and woody encroachment...
2017: PloS One
https://www.readbyqxmd.com/read/28631456/comparison-between-adenosine-and-magnesium-sulphate-as-adjuvants-for-transversus-abdominis-plane-block-a-prospective-randomized-controlled-trial
#6
Amany S Ammar, Khaled M Mahmoud, Zeinab A Kasemy
BACKGROUND: Various adjuvants have been employed during different nerve blocks. We aimed to evaluate the effect of adding adenosine versus magnesium sulfate to bupivacaine on the quality and duration of transversus abdominis plane (TAP) block. METHODS: Participants were randomized to TAP block using either 20 ml of bupivacaine hydrochloride 0.375% + 12 mg adenosine in 2 ml of saline 0.9% (adenosine group), 20 ml of bupivacaine hydrochloride 0.375% + 500 mg magnesium sulphate in 2 ml saline 0...
June 14, 2017: Minerva Anestesiologica
https://www.readbyqxmd.com/read/28612671/racial-ethnic-disparities-in-magnesium-sulphate-neuroprotection-a-subgroup-analysis-of-a-multicenter-randomized-controlled-trial
#7
Gustavo Vilchez, Jing Dai, Komal Kumar, David Mundy, Eftichia Kontopoulos, Robert J Sokol
OBJECTIVE: Despite known racial disparities in obstetrics, as well as differences in magnesium pharmacodynamics according to race, the effect of race/ethnicity in magnesium sulphate (MgSO4) use during pregnancy has not been studied. Whether some mothers are at increased risk of side effects, or infants at decreased neuroprotective effects is unknown. We analyze the effect of race/ethnicity in maternal/infant outcomes after MgSO4 neuroprotection. STUDY DESIGN: Subgroup analysis of a multicenter clinical trial (BEAM trial) where pregnant women at risk of preterm birth were randomized to either MgSO4 or placebo...
June 14, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28584351/the-effects-of-dexmedetomidine-and-magnesium-sulphate-in-adult-patients-undergoing-endoscopic-transnasal-transsphenoidal-resection-of-pituitary-adenoma-a-double-blind-randomised-study
#8
Rabie Soliman, Eman Fouad
BACKGROUND AND AIM: Transnasal transsphenoidal resection of pituitary tumours is associated with blood loss and wide fluctuations in haemodynamic parameters. The aim of the present study was to compare the effect of dexmedetomidine and magnesium sulphate during the transsphenoidal resection of pituitary tumours. METHODS: The study was a double-blind, randomised study and included 152 patients classified randomly into two groups: Group D: Dexmedetomidine was given as a loading dose 1 μg/kg over 10 min before induction followed by an infusion at 0...
May 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28544600/effect-of-magnesium-on-arrhythmia-incidence-in-patients-undergoing-coronary-artery-bypass-grafting
#9
Alireza Mohammadzadeh, Farshad Towfighi, Naser Jafari
BACKGROUND: Cardiac arrhythmia after coronary artery bypass grafting (CABG) surgery is a common complication of cardiac surgery. The effect of serum magnesium, hypomagnesaemia treatment and prophylactic administration of magnesium in the development and prevention of arrhythmias is controversial and there are many different ideas. This study evaluates the therapeutic effects of magnesium in cardiac arrhythmia after CABG surgery. METHODS: The clinical trial enrolled 250 patients who underwent CABG...
May 22, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28501278/antenatal-risk-factors-associated-with-need-of-postpartum-antihypertensives-in-women-with-preeclampsia-in-south-india-case-control-study
#10
Anish Keepanasseril, Brajesh Kumar Yadav, Dilip Kumar Maurya
OBJECTIVES: To investigate the antepartum risk factors associated with the need for antihypertensive medication in the postpartum period in women with pre-eclampsia. METHODOLOGY: Matched retrospective case control study was done in a tertiary center in south India between January 2016 and June 2016. We compared 100 preeclamptic women requiring antihypertensive medication in the postpartum period at discharge with 100 preeclamptic women who were not on antihypertensive medication at discharge, matched for age and parity at a ratio 1:1...
April 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/28494422/cyanobacteria-blooms-before-and-during-the-restoration-process-of-a-shallow-urban-lake
#11
Joanna Rosińska, Anna Kozak, Renata Dondajewska, Ryszard Gołdyn
Swarzędzkie Lake (near Poznań) has been heavily polluted. To improve the water quality, the restoration of lake by three methods: aeration, phosphorus inactivation using small doses of iron sulphate and magnesium chloride (FeSO4 and MgCl2) and biomanipulation was initiated at the end of 2011. The aim of the present study was to determine whether sustainable restoration has a significant impact on phytoplankton, especially cyanobacterial blooms in a shallow, urban, degraded lake. Therefore, phytoplankton and the physico-chemical parameters of water at the summer thermal stratification and autumn water mixing before (2011) and during restoration (2012-2014) was studied...
May 7, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28464014/analgesic-effect-of-perineural-magnesium-sulphate-for-sciatic-nerve-block-for-diabetic-toe-amputation-a-randomized-trial
#12
Jiehao Sun, Xiaona Feng, Qihan Zhu, Wendong Lin, Hailei Guo, Emmanuel Ansong, Le Liu
BACKGROUND AND OBJECTIVES: High concentrations of local anesthetics may be neurotoxic for diabetic patients. Additive perineural administration of magnesium was reported to decrease the consumption of local anesthetics for nerve block. It was hypothesized that MgSO4 added to dilute ropivacaine was equianalgesic to more concentrated ropivacaine for toe amputations in diabetic patients. METHODS: Seventy diabetic patients were allocated into 3 groups: 1) perineural 200 mg MgSO4 added to 0...
2017: PloS One
https://www.readbyqxmd.com/read/28437264/magnesium-sulphate-improves-pulmonary-function-after-video-assisted-thoracoscopic-surgery-a-randomised-double-blind-placebo-controlled-study
#13
Hye-Min Sohn, Sang-Hoon Jheon, Sunwoo Nam, Sang-Hwan Do
BACKGROUND: Reduced lung volumes are unavoidable after lung resection surgery. Magnesium sulphate (MgSO4) administration has been reported to reduce the requirement for neuromuscular blocking drugs and postoperative analgesics in surgical patients. OBJECTIVE: To investigate the effect of MgSO4 on pulmonary function after video-assisted thoracoscopic surgery (VATS). DESIGN: A randomised, double-blind, placebo-controlled trial. SETTING: A university tertiary care centre...
August 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28421842/the-management-of-ventricular-dysrhythmia-in-aconite-poisoning
#14
REVIEW
James M Coulson, Thomas M Caparrotta, John P Thompson
INTRODUCTION: Aconite poisoning is relatively rare but is frequently complicated by ventricular dysrhythmias, which may be fatal. Molecular basis of aconite alkaloid ventricular arrhythmogenicity: Aconite exerts its toxic effects due to the presence of an admixture of alkaloids present in all parts of the plant. The major target of these aconite alkaloids is the fast voltage-gates sodium channel, where they cause persistent activation. This blockade of the channel in the activated state promotes automaticity within the ventricular myocardium and the generation of ventricular arrhythmias...
June 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28412995/development-and-validation-of-prediction-models-for-risks-of-complications-in-early-onset-pre-eclampsia-prep-a-prospective-cohort-study
#15
Shakila Thangaratinam, John Allotey, Nadine Marlin, Ben W Mol, Peter Von Dadelszen, Wessel Ganzevoort, Joost Akkermans, Asif Ahmed, Jane Daniels, Jon Deeks, Khaled Ismail, Ann Marie Barnard, Julie Dodds, Sally Kerry, Carl Moons, Richard D Riley, Khalid S Khan
BACKGROUND: The prognosis of early-onset pre-eclampsia (before 34 weeks' gestation) is variable. Accurate prediction of complications is required to plan appropriate management in high-risk women. OBJECTIVE: To develop and validate prediction models for outcomes in early-onset pre-eclampsia. DESIGN: Prospective cohort for model development, with validation in two external data sets. SETTING: Model development: 53 obstetric units in the UK...
April 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28412496/magnesium-sulfate-mg-prevents-maternal-inflammation-induced-offspring-cerebral-injury-evident-on-mri-but-not-via-il-1%C3%AE
#16
Yuval Ginsberg, Nizar Khatib, Boaz Weiss, Shay Arison, Michael G Ross, Zeev Weiner, Ron Beloosesky
OBJECTIVE: As maternal treatment with magnesium sulfate (MG) may protect the fetal brain, we sought to assess the inflammation associated neuroprotective potential of MG and its association to interleukin 1β (IL-1β). METHODS: Pregnant Sprague-Dawley rats at 18-day gestation received i.p. lipopolysaccharide (LPS) or saline. Dams were randomized to treatment with s.c. saline (control), or MG prior to or following the i.p. injection, resulting in three groups. At the end of the treatment, fetal brain IL-1β was quantified for 18 pregnant rats (six of each group)...
April 12, 2017: Neuroscience
https://www.readbyqxmd.com/read/28409830/magnesium-for-treating-sickle-cell-disease
#17
REVIEW
Nan Nitra Than, Htoo Htoo Kyaw Soe, Senthil K Palaniappan, Adinegara Bl Abas, Lucia De Franceschi
BACKGROUND: Sickle cell disease is an autosomal recessive inherited haemoglobinopathy which causes painful vaso-occlusive crises due to sickle red blood cell dehydration. Vaso-occlusive crises are common painful events responsible for a variety of clinical complications; overall mortality is increased and life expectancy decreased compared to the general population. Experimental studies suggest that intravenous magnesium has proven to be well-tolerated in individuals hospitalised for the immediate relief of acute (sudden onset) painful crisis and has the potential to decrease the length of hospital stay...
April 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28405040/a-dose-finding-randomised-controlled-trial-of-magnesium-sulphate-as-an-adjuvant-in-ultrasound-guided-supraclavicular-brachial-plexus-block
#18
Versha Verma, Shelly Rana, Sudarshan Kumar Chaudhary, Jai Singh, Ravinder Kumar Verma, Saloni Sood
BACKGROUND AND AIM: Magnesium sulphate (MgSO4) has been used as an adjuvant in brachial plexus block with encouraging results; however, there is no consensus regarding its optimal dose. Thereby, we compared the efficacy of two doses of MgSO4 as an adjuvant in ultrasound (USG) guided supraclavicular brachial plexus block. METHODS: Ninety patients, aged 20-60 years, belonging to American Society of Anesthesiologists physical status 1 or 2, were given USG-guided supraclavicular block...
March 2017: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/28396170/addendum-to-process-development-for-elemental-recovery-from-pgm-tailings-by-thermochemical-treatment-preliminary-major-element-extraction-studies-using-ammonium-sulphate-as-extracting-agent-waste-manage-50-2016-334-345
#19
Sameera Mohamed, Elizabet M van der Merwe, Wladyslaw Altermann, Frédéric J Doucet
In a recent paper, a promising two-stage process for the extraction of major elements from Platinum Group Metals (PGM) was presented (Mohamed et al., 2016). This process involved solid-solid thermochemical treatment of tailings with ammonium sulphate (stage one), followed by an optimised acid dissolution step (stage two). The inclusion of a control experiment for the optimal dissolution procedure was however overlooked. The new set of data delivered by the control experiment reveals that (i) most of the silicon and calcium are extracted via the acid leaching step, (ii) aluminium and magnesium are extracted at each stage of the process, and (iii) the thermochemical step is the main contributor to chromium and iron extraction...
April 7, 2017: Waste Management
https://www.readbyqxmd.com/read/28365673/can-zinc-supplementation-ameliorate-cadmium-induced-alterations-in-the-bioelement-content-in-rabbits
#20
Zorica Bulat, Danijela Đukić-Ćosić, Biljana Antonijević, Aleksandra Buha, Petar Bulat, Zoran Pavlović, Vesna Matović
The study was designed to investigate the influence of zinc (Zn) supplementation on cadmium-induced alterations in zinc, copper (Cu), and magnesium (Mg) status in rabbits. For this purpose, the concentrations of cadmium (Cd), Zn, Cu, and Mg were estimated in the blood, liver, kidney, and bone. The rabbits were divided in a control group, a Cd group-animals intoxicated orally with Cd (10 mg kg-1 bw, as aqueous solution of Cd-chloride), and a Cd+Zn group-animals intoxicated with the same dose of Cd and co-treated with Zn (20 mg kg-1 bw, as aqueous solution of Zn-sulphate)...
March 1, 2017: Arhiv za Higijenu Rada i Toksikologiju
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