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Cervical manipulation

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https://www.readbyqxmd.com/read/28528932/robot-assisted-gynaecological-cancer-surgery-complications-and-prevention
#1
REVIEW
Ka Yu Tse, Hextan Yuen Sheung Ngan, Peter Christopher Lim
Ever since the US Food and Drug Administration approval of the use of da Vinci surgical systems (Intuitive Surgical Inc., Sunnyvale, California) in gynaecology in 2005, robot-assisted surgery has been widely adopted in different countries. Some of the applications in benign and oncological gynaecology include myomectomy, sacrocolpopexy, tubal anastomosis, simple hysterectomy, radical hysterectomy, radical trachelectomy, pelvic and/or para-aortic lymphadenectomy and even debulking surgery for ovarian cancer and pelvic exenteration for recurrent cervical and vaginal cancer...
April 23, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28505959/the-application-of-a-pre-positioned-upper-cervical-traction-mobilization-to-patients-with-painful-active-cervical-rotation-impairment-a-case-series
#2
Douglas S Creighton, Doug Marsh, Mark Gruca, Melissa Walter
BACKGROUND: Cervical mobilization and manipulation have been shown to improve cervical range of motion and pain. Cervical rotatory thrust manipulation has been associated with adverse patient reaction and damage to the V3 segment of the vertebral artery (VA). OBJECTIVE: To document and describe the effects of an upper cervical (UC) traction based mobilization on participants with restricted and painful cervical rotation and to document if the mobilization changed blood flow velocity through the vertebral artery...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28505955/the-immediate-effects-of-manual-stretching-and-cervicothoracic-junction-manipulation-on-cervical-range-of-motion-and-upper-trapezius-pressure-pain-thresholds
#3
William J Hanney, Emilio Puentedura, Morey J Kolber, Xinliang Liu, Patrick S Pabian, Scott Cheatham
INTRODUCTION: Myofascial pain is a common impairment treated with various manual interventions including spinal thrust manipulation and stretching; however, the comparative efficacy of each intervention is uncertain. Therefore, the purpose of this investigation was to evaluate thrust manipulation targeting the cervicothoracic junction compared to a manual stretch of the upper trapezius muscle on cervical range of motion and upper trapezius pressure pain thresholds (PPTs). METHODS: Healthy participants with no significant history of neck pain were randomized into a thrust manipulation group, a stretching group, or a control group...
May 5, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28499198/a-point-of-need-infrared-mediated-pcr-platform-with-compatible-lateral-flow-strip-for-hpv-detection
#4
Wenjia Liu, Mingfang Zhang, Xiaoyan Liu, Alok Sharma, Xianting Ding
With the increasing need of monitoring the epidemiology of serious infectious diseases, food hygiene, food additives and pesticide residues, it is urgent to develop portable, easy-to-use, inexpensive and rapid molecular diagnostic tools. Herein, we demonstrate a prototype of IR mediated Conducting Oil and CarbOn Nanotube circUlaTing PCR (IR-COCONUT PCR) platform for nucleic acid amplification. The presented platform offers a new solution for miniaturized PCR instruments with non-contact heaters by using conducting oil and carbon nanotube as a medium in IR mediated PCR...
April 29, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28494130/visualization-of-stereoscopic-anatomic-models-of-the-paranasal-sinuses-and-cervical-vertebrae-from-the-surgical-and-procedural-perspective
#5
Jian Chen, Andrew D Smith, Majid A Khan, Allan R Sinning, Marianne L Conway, Dongmei Cui
Recent improvements in three-dimensional (3D) virtual modeling software allows anatomists to generate high-resolution, visually appealing, colored, anatomical 3D models from computed tomography (CT) images. In this study, high-resolution CT images of a cadaver were used to develop clinically relevant anatomic models including facial skull, nasal cavity, septum, turbinates, paranasal sinuses, optic nerve, pituitary gland, carotid artery, cervical vertebrae, atlanto-axial joint, cervical spinal cord, cervical nerve root, and vertebral artery that can be used to teach clinical trainees (students, residents, and fellows) approaches for trans-sphenoidal pituitary surgery and cervical spine injection procedure...
May 11, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/28479402/tight-neurovascular-coupling-in-the-spinal-cord-during-nociceptive-stimulation-in-intact-and-spinal-rats
#6
Mathieu Piché, Thierry Paquette, Hugues Leblond
Functional magnetic resonance imaging (fMRI) is based on neurovascular coupling, which allows inferring neuronal activity from hemodynamic changes. Spinal fMRI has been used to examine pain processes, although spinal neurovascular coupling has never been investigated. In addition, fluctuations in mean arterial pressure (MAP) occur during nociceptive stimulation and this may affect neurovascular coupling. The objective of this study was to examine neurovascular coupling in the rat spinal cord during nociceptive stimulation while MAP was manipulated by cervical spinal transection, which prevents nociception-related MAP increases...
May 4, 2017: Neuroscience
https://www.readbyqxmd.com/read/28457862/the-vertebral-nerve-a-comprehensive-review-of-its-form-and-function
#7
REVIEW
Jaspreet Johal, Sharath S BelElary, Elizabeth A Lax, Gopi K Maharaja, Rod J Oskouian, Marios Loukas, R Shane Tubbs
The literature is littered with variable and scant reports of the vertebral nerve. The present paper reviews the literature regarding this nervous structure of the neck and attempts to clarify a number of issues surrounding its form, function, and implications of surgical manipulation. The nerve may arise from the stellate ganglion or the ansa subclavia, amongst a number of other structures. Additionally, the terminal insertion of the vertebral nerve varies in the reported literature, with authors observing various terminations...
April 27, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28451496/carotid-artery-injury-in-anterior-cervical-spine-surgery-multicenter-cohort-study-and-literature-review
#8
Roger Härtl, Marjan Alimi, Mohamed Abdelatif Boukebir, Connor D Berlin, Rodrigo Navarro-Ramirez, Paul M Arnold, Michael G Fehlings, Thomas E Mroz, K Daniel Riew
STUDY DESIGN: Retrospective study and literature review. OBJECTIVE: To provide more comprehensive data about carotid artery injury (CAI) or cerebrovascular accident (CVA) related to anterior cervical spine surgery. METHODS: We conducted a retrospective, multicenter, case series study involving 21 high-volume surgical centers from the AOSpine North America Clinical Research Network. Medical records of 17 625 patients who went through cervical spine surgery (levels from C2 to C7) between January 1, 2005, and December 31, 2011, were analyzed...
April 2017: Global Spine Journal
https://www.readbyqxmd.com/read/28449663/mir-23b-controls-aldh1a1-expression-in-cervical-cancer-stem-cells
#9
Weiwen Wang, Yang Li, Na Liu, Yu Gao, Long Li
BACKGROUND: Cancer stem cells has been widely investigated due to its essential role in cancer progression and drug resistance. Here, we try to find a new therapeutic target for cervical cancer stem cells. METHODS: We detected ALDH1A1-associated miRNAs expression in our isolated tumorspheres and their corresponding parental cells. Sphere formation assay was also used to determine stemness after cells were manipulated with miR-23b plasmid or miR-23b inhibitor. RESULTS: We found that miR-23b was under-expressed in cervical cancer stem cells to maintain high levels of ALDH1A1...
April 27, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28415759/kshv-co-infection-down-regulates-hpv16-e6-and-e7-from-cervical-cancer-cells
#10
Lu Dai, Yueyu Cao, Wei Jiang, Jovanny Zabaleta, Zhongmin Liu, Jing Qiao, Zhiqiang Qin
High-risk human papillomavirus (HPV) infection is the etiological agent of some malignancies such as cervical, oral and oropharyngeal cancers. Kaposi sarcoma-associated herpesvirus (KSHV) represents a principal causative agent of several human cancers arising in those immunocompromised patients. Interestingly, KSHV DNA has been detected in the oral cavity and the female genital tract, although its detection rate in cervical samples is very low and few reports are about KSHV/HPV co-infection. Therefore, it remains unclear about the role of KSHV co-infection in the development of HPV-related neoplasias...
March 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28357377/chlamydia-trachomatis-genital-infections
#11
REVIEW
Catherine M O'Connell, Morgan E Ferone
Etiology, transmission and protection: Chlamydia trachomatis is the leading cause of bacterial sexually transmitted infection (STI) globally. However, C. trachomatis also causes trachoma in endemic areas, mostly Africa and the Middle East, and is a leading cause of preventable blindness worldwide. Epidemiology, incidence and prevalence: The World Health Organization estimates 131 million new cases of C. trachomatis genital infection occur annually. Globally, infection is most prevalent in young women and men (14-25 years), likely driven by asymptomatic infection, inadequate partner treatment and delayed development of protective immunity...
September 5, 2016: Microbial Cell
https://www.readbyqxmd.com/read/28338752/strategies-for-evaluating-the-assumptions-of-the-regression-discontinuity-design-a-case-study-using-a-human-papillomavirus-vaccination-programme
#12
Leah M Smith, Linda E Lévesque, Jay S Kaufman, Erin C Strumpf
Background: The regression discontinuity design (RDD) is a quasi-experimental approach used to avoid confounding bias in the assessment of new policies and interventions. It is applied specifically in situations where individuals are assigned to a policy/intervention based on whether they are above or below a pre-specified cut-off on a continuously measured variable, such as birth date, income or weight. The strength of the design is that, provided individuals do not manipulate the value of this variable, assignment to the policy/intervention is considered as good as random for individuals close to the cut-off...
October 8, 2016: International Journal of Epidemiology
https://www.readbyqxmd.com/read/28336131/modulating-the-dna-damage-response-to-improve-treatment-response-in-cervical-cancer
#13
L H Cossar, A G Schache, J M Risk, J J Sacco, N J Jones, R Lord
Cervical cancer is the fourth most common cause of cancer-related death in women worldwide and new therapeutic approaches are needed to improve clinical outcomes for this group of patients. Current treatment protocols for locally advanced and metastatic disease consist of ionising radiation and chemotherapy. Chemoradiation induces cytotoxic levels of DNA double-strand breaks, which activates programmed cell death via the DNA damage response (DDR). Cervical cancers are unique given an almost exclusive association with human papillomavirus (HPV) infection; a potent manipulator of the DDR, with the potential to alter tumour sensitivity to DNA-damaging agents and influence treatment response...
March 20, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28324213/-split-and-splayed-c3-traumatic-lateral-c2-3-dislocation-without-neurological-deficits-unique-case-and-its-management
#14
Apinderpreeet Singh, Pravin Salunke, Rajeev P Kamble
BACKGROUND: Traumatic C2-3 dislocation has been often described in the antero-posterior plane but is extremely rare in the lateral plane. Such dislocations have been described in thoraco-lumbar and C1-2. The need to study the imaging in multiple planes has been highlighted to plan proper realignment. METHODS: A young male presented with neck pain alone following a train accident. The imaging showed a fracture of C3 splaying it. The C2-3 showed lateral dislocation in the lateral plane with locked C2-3 facets on one side and C3-4 facets on the other...
March 21, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28303160/cervical-rotatory-manipulation-decreases-uniaxial-tensile-properties-of-rabbit-atherosclerotic-internal-carotid-artery
#15
Shaoqun Zhang, Ji Qi, Lei Zhang, Chao Chen, Shubhro Mondal, Kaike Ping, Yili Chen, Yikai Li
Objective. To investigate the effects of one of the Chinese massage therapies, cervical rotatory manipulation (CRM), on uniaxial tensile properties of rabbit atherosclerotic internal carotid artery (ICA). Methods. 40 male purebred New Zealand white rabbits were randomly divided into CRM-Model group, Non-CRM-Model group, CRM-Normal group, and Non-CRM-Normal group. After modeling (atherosclerotic model) and intervention (CRM or Non-CRM), uniaxial tensile tests were performed on the ICAs to assess the differences in tensile mechanical properties between the four groups...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28274487/manipulation-peak-forces-across-spinal-regions-for-children-using-mannequin-simulators
#16
John J Triano, Steven Lester, David Starmer, Elise G Hewitt
OBJECTIVE: The purpose of this work was to create an exploratory database of manipulation treatment force variability as a function of the intent of an experienced clinician sub-specializing in the care of children to match treatment to childhood category. Data of this type are necessary for realistic planning of dose-response and safety studies on therapeutic benefit. METHODS: The project evaluated the transmitted peak forces of procedures applied to mannequins of different stature for younger and older children...
March 5, 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28265158/effects-of-manipulation-of-the-thorax-and-intensity-of-the-pressure-biofeedback-unit-on-the-superficial-cervical-flexors-muscle-during-craniocervical-flexion-exercise
#17
Jin Mo Yang, Hyun-Gyu Cha, Myoung-Kwon Kim
[Purpose] This study examined the effects of manipulation of the thorax and the intensity of the pressure biofeedback unit on the superficial cervical flexors muscle during craniocervical flexion exercise. [Subjects and Methods] Thirty three subjects participated in the experiment. Thirty three healthy people without any orthopedic history were also selected. The subjects could monitor the pressure applied to cervical vertebra 3 of the craniocervical junction by markings on the pressure biofeedback unit. Craniocervical flexion exercise was performed for 20 seconds per pressure, and two minutes of rest was allowed after exercise to reduce muscle fatigue...
February 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28261334/twist1-enhances-hypoxia-induced-radioresistance-in-cervical-cancer-cells-by-promoting-nuclear-egfr-localization
#18
Hua Xiong, Xin Nie, Yanmei Zou, Chen Gong, Yang Li, Hua Wu, Hong Qiu, Lin Yang, Liang Zhuang, Peng Zhang, Jing Zhang, Yihua Wang, Huihua Xiong
Twist1 is a crucial transcription factor that regulates epithelial mesenchymal transition and involves in metastasis. Recent evidence suggests that Twist1 plays important role in hypoxia-induced radioresistance, but the underlying mechanism remains elusive. Here we investigated the change of Twist1 expression in human cervical squamous cancer cell line SiHa after hypoxia treatment. We also explored the role of Twist1 in radioresistance by manipulating the expression level of Twist1. We observed that hypoxia treatment elevated the expression of Twist1 in SiHa cells...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28254504/robotic-assisted-laparoscopic-trachelectomy-a-standard-technique
#19
Mohamad S Mahmoud
STUDY OBJECTIVE: To describe a standard reproducible technique for simple robotic- assisted laparoscopic trachelectomy. DESIGN: Step-by-step demonstration of the technique using videos and pictures (Canadian Task Force classification level 3). SETTING: The incidence of trachelectomy after supracervical hysterectomy has been increasing, given the popularity of supracervical hysterectomy. The most common indication for trachelectomy is symptomatic cyclic bleeding...
February 27, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/28253371/autophagy-regulates-ubc9-levels-during-viral-mediated-tumorigenesis
#20
Domenico Mattoscio, Chiara Casadio, Claudia Miccolo, Fausto Maffini, Andrea Raimondi, Carlo Tacchetti, Tarik Gheit, Marta Tagliabue, Viviana E Galimberti, Francesca De Lorenzi, Michael Pawlita, Fausto Chiesa, Mohssen Ansarin, Massimo Tommasino, Susanna Chiocca
UBC9, the sole E2-conjugating enzyme required for SUMOylation, is a key regulator of essential cellular functions and, as such, is frequently altered in cancers. Along these lines, we recently reported that its expression gradually increases during early stages of human papillomavirus (HPV)-mediated cervical lesions transformation. However, a better understanding of how UBC9 is exploited by transforming viral oncoproteins is still needed. In the present study, we show that in human samples HPV drives UBC9 up-regulation also in very early steps of head and neck tumorigenesis, pointing to the important role for UBC9 in the HPV-mediated carcinogenic program...
March 2017: PLoS Pathogens
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