keyword
https://read.qxmd.com/read/38644925/immediate-postoperative-resolution-of-syrinx-post-c1-c2-fixation-in-an-operated-case-of-foramen-magnum-decompression-for-chiari-malformation-is-goel-s-procedure-a-rescue-surgery-or-a-gold-standard
#1
Ashish Chugh, Prashant Punia, Sarang Gotecha, Jayant Arun Gaud, Rajeev Reddy, Ramis Abdul Aziz
Chiari malformation (CM) is a common neurological disorder with foramen magnum decompression (FMD) as a commonly accepted treatment. The authors present a case of CM-1 wherein there was no radiological instability preoperatively and FMD was done as a treatment, after which the patient improved transiently only to deteriorate further. Atlantoaxial fixation was done as a second-stage procedure, after which the patient improved clinically and radiologically. The knowledge of this case and surgical entity should be borne in mind before the formulation of a treatment plan...
2024: Journal of Craniovertebral Junction and Spine
https://read.qxmd.com/read/38644907/defining-role-of-atlantoaxial-and-subaxial-spinal-instability-in-the-pathogenesis-of-cervical-spinal-degeneration-experience-with-only-fixation-without-any-decompression-as-treatment-in-374-cases-over-10-years
#2
JOURNAL ARTICLE
Atul Goel, Ravikiran Vutha, Abhidha Shah, Apurva Prasad, Ashutosh Kumar Shukla, Shradha Maheshwari
AIM: The authors analyze their published work and update their experience with 374 cases of cervical radiculopathy and/or myelopathy related to spinal degeneration that includes ossification of the posterior longitudinal ligament (OPLL). The role of atlantoaxial and subaxial spinal instability as the nodal point of pathogenesis and focused target of surgical treatment is analyzed. MATERIALS AND METHODS: During the period from June 2012 to November 2022, 374 patients presented with acute or chronic symptoms related to radiculopathy and/or myelopathy that were attributed to degenerative cervical spondylotic changes or due to OPLL...
2024: Journal of Craniovertebral Junction and Spine
https://read.qxmd.com/read/38639146/-efficacy-of-manual-correction-of-cervical-spine-osteochondrosis-in-the-treatment-of-arterial-hypertension-syndrome-and-prediabetes
#3
JOURNAL ARTICLE
A Yu Shishonin, E V Yakovleva, K V Zhukov, A A Vecher, B A Gasparyan, V I Pavlov
UNLABELLED: Cardiovascular diseases and diabetes mellitus, debuting as arterial hypertension (AH) syndrome and prediabetes, are common types of chronic non-communicable processes, that are the leading cause of death in the world. The main treatment method for above mentioned disorders, according to the current guidelines, is pharmacotherapy. However, it is possible to effectively apply non-pharmacological correction methods, aimed at the probable etiological factor and inversive mechanism involved in AH maintenance, in the early stages when no permanent changes are maintaining a high level of blood hypertension (BH) and glycemia...
2024: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://read.qxmd.com/read/38626497/quantitatively-assessing-the-effect-of-cervical-sagittal-alignment-on-dynamic-intervertebral-kinematics-by-video-fluoroscopy-technique
#4
JOURNAL ARTICLE
Ning Qu, JiaHao Jin, Xu Wang, YanQun Deng, Bin Zhang, QiHua Qi
BACKGROUND: Cervical sagittal alignment is crucial for distributing the head load to lower cervical segments and maintaining normal cervical spine function, but its biomechanical effect on the cervical spine was not fully elucidated. OBJECTIVE: To investigate the effect of cervical sagittal alignment on dynamic intervertebral kinematics. DESIGN: Cross-sectional study. METHODS: Healthy participants without neck pain were recruited and divided into lordosis, straight and kyphosis groups according to the C2-C7 Cobb angle at the neutral position...
April 11, 2024: Musculoskeletal Science & Practice
https://read.qxmd.com/read/38626267/evidence-for-vagal-sensory-neural-involvement-in-influenza-pathogenesis-and-disease
#5
JOURNAL ARTICLE
Nathalie A J Verzele, Brendon Y Chua, Kirsty R Short, Aung Aung Kywe Moe, Isaac N Edwards, Helle Bielefeldt-Ohmann, Katina D Hulme, Ellesandra C Noye, Marcus Z W Tong, Patrick C Reading, Matthew W Trewella, Stuart B Mazzone, Alice E McGovern
Influenza A virus (IAV) is a common respiratory pathogen and a global cause of significant and often severe morbidity. Although inflammatory immune responses to IAV infections are well described, little is known about how neuroimmune processes contribute to IAV pathogenesis. In the present study, we employed surgical, genetic, and pharmacological approaches to manipulate pulmonary vagal sensory neuron innervation and activity in the lungs to explore potential crosstalk between pulmonary sensory neurons and immune processes...
April 16, 2024: PLoS Pathogens
https://read.qxmd.com/read/38617545/tie1-promotes-cervical-cancer-progression-via-basigin-matrix-metalloproteinase-axis
#6
JOURNAL ARTICLE
Pan Liu, Lisha Xie, Qiulei Wu, Lin Huang, Xiaoli Liu, Wenhan Li, Jing Cai, Zehua Wang, Ping Yang, Liqiong Cai
Background: Tyrosine kinase with immunoglobulin and EGF-like domains 1 (TIE1) is known as an orphan receptor prominently expressed in endothelial cells and participates in angiogenesis by regulating TIE2 activity. Our previous study demonstrated elevated TIE1 expression in cervical cancer cells. However, the role of TIE1 in cervical cancer progression, metastasis and treatment remains elusive. Methods: Immunohistochemistry staining for TIE1 and Basigin was performed in 135 human cervical cancer tissues. Overexpressing vectors and siRNAs were used to manipulate gene expression in tumor cells...
2024: International Journal of Biological Sciences
https://read.qxmd.com/read/38615408/ultrasonographic-measurement-indicated-patients-with-chronic-neck-pain-had-reduced-diaphragm-thickness-and-mobility-along-with-declined-respiratory-functions
#7
JOURNAL ARTICLE
Everlynn Yi-Xuan Hii, Yi-Liang Kuo, Kai-Chia Cheng, Ching-Hsia Hung, Yi-Ju Tsai
BACKGROUND: Chronic neck pain (CNP) is a prevalent musculoskeletal condition including notable impairments in respiratory function. The diaphragm, serving dual roles in respiration and spinal stability, is intricately linked to the cervical spine through fascial, neurophysiological, and biomechanical connections. However, to date, none has investigated the diaphragm function in patients with CNP. OBJECTIVES: To investigate the diaphragm function, respiratory muscle strength, and pulmonary function in patients with CNP...
April 2, 2024: Musculoskeletal Science & Practice
https://read.qxmd.com/read/38605158/novel-drug-delivery-approaches-for-the-localized-treatment-of-cervical-cancer
#8
REVIEW
Ivy Saha, Jitu Halder, Tushar Kanti Rajwar, Ritu Mahanty, Deepak Pradhan, Priyanka Dash, Chandan Das, Vineet Kumar Rai, Biswakanth Kar, Goutam Ghosh, Goutam Rath
Cervical cancer (CC) is the fourth leading cancer type in females globally. Being an ailment of the birth canal, primitive treatment strategies, including surgery, radiation, or laser therapy, bring along the risk of infertility, neonate mortality, premature parturition, etc. Systemic chemotherapy led to systemic toxicity. Therefore, delivering a smaller cargo of therapeutics to the local site is more beneficial in terms of efficacy as well as safety. Due to the regeneration of cervicovaginal mucus, conventional dosage forms come with the limitations of leaking, the requirement of repeated administration, and compromised vaginal retention...
April 11, 2024: AAPS PharmSciTech
https://read.qxmd.com/read/38604263/ovarian-tissue-biopsy-for-cryopreservation-by-vaginal-natural-orifice-transluminal-endoscopic-surgery-vnotes-a-new-approach-for-a-minimal-invasive-ovarian-biopsy
#9
JOURNAL ARTICLE
Renato Seracchioli, Manuela Maletta, Enrico Pazzaglia, Antonio Raffone, Rossella Vicenti, Stefano Scarperi, Valentino Bergamini, Diego Raimondo
OBJECTIVE: Vaginal natural orifice transluminal endoscopic surgery (vNOTES) is an emerging surgical procedure that combines the advantages of the vaginal approach with laparoscopic vision and instrumentation [1]. Shorter hospitalization and lower postoperative pain associated to vNOTES [2] may be explained by the advantages of this innovative surgical approach (such as absence of abdominal incisions, shorter operating time, lower insufflation pressure) [2;3]. Ovarian tissue cryopreservation allows to preserve reproductive and endocrine functions in young women with oncological disease at risk of premature ovarian insufficiency (POI) caused by gonadotoxic treatments [4]...
April 9, 2024: Fertility and Sterility
https://read.qxmd.com/read/38597603/exclusive-transcervical-drainage-for-posterior-mediastinal-abscess-originating-from-a-mandibular-molar
#10
JOURNAL ARTICLE
Masato Nagaoka, Masaomi Motegi
The progression of a cervical abscess toward the mediastinum is rare but remains one of the most serious diseases, even in the era of antibiotics. A mediastinal abscess can originate from an odontogenic infection and presents a challenge for otolaryngologists and craniofacial surgeons, particularly when it spreads caudally to the tracheal bifurcation. For successful treatment of such an abscess, patients are generally referred to a thoracic surgeon for drainage. We present a distinctive case of an odontogenic infection-induced wide mediastinal abscess that could be drained only through cervical manipulation by using a sump-type tube...
April 10, 2024: Journal of Craniofacial Surgery
https://read.qxmd.com/read/38586711/comprehensive-physiotherapeutic-management-of-atlas-occipitalization-a-case-report
#11
Anandi R Dave, Mitushi A Deshmukh, Siddhant S Deshmukh
The atlas (C1) and occipital bone at the base of the skull fuse together in atlas occipitalization, an uncommon congenital abnormality. Because it can result in cervical spine instability, nerve impingement, and related symptoms including stiffness, pain, and neurological impairments, it poses a challenging therapeutic problem. We describe the case of a female patient, 27 years old, who had gradually deteriorating neck discomfort, stiffness, and limited cervical mobility for six years prior to presentation...
March 2024: Curēus
https://read.qxmd.com/read/38574577/measurement-proprieties-of-the-crom-instrument-for-assessing-head-posture-neck-retraction-and-protraction
#12
JOURNAL ARTICLE
Ignacio Elizagaray-García, Álvaro Obispo-Villamayor, Celia Prats-Martínez, Gonzalo Prieto-Hernández, Gabriela Ferreira Carvalho
BACKGROUND: The CROM instrument is widely used clinically and in research to measure neck range of motion. However, its measurement proprieties during the assessment of protraction and retraction movements were not examined so far. OBJECTIVE: To analyse the intra- and inter-rater reliability, the concurrent validity of the CROM for measuring head posture, retraction and protraction in healthy subjects. METHODS: Thirty-three asymptomatic subjects were recruited and assigned in a random order to one of two raters...
March 29, 2024: Musculoskeletal Science & Practice
https://read.qxmd.com/read/38570915/mckenzie-neck-exercise-versus-cranio-cervical-flexion-exercise-on-strength-and-endurance-of-deep-neck-flexor-muscles-pain-disability-and-craniovertebral-angle-in-individuals-with-chronic-neck-pain-a-randomized-clinical-trial
#13
JOURNAL ARTICLE
Sawita Chaiyawijit, Rotsalai Kanlayanaphotporn
PURPOSE: To compare the effectiveness of McKenzie neck exercise and cranio-cervical flexion (CCF) exercise on strength and endurance of deep neck flexor (DNF) muscles, pain, disability, and craniovertebral angle (CVA) in individuals with chronic neck pain. METHODS: Forty individuals with chronic neck pain were randomly allocated to the McKenzie neck or CCF exercise group. Each group performed exercises at home daily. The strength and endurance of DNF muscles were measured at baseline, immediately after the first exercise session, and each week follow-up for six weeks...
April 3, 2024: Journal of Manual & Manipulative Therapy
https://read.qxmd.com/read/38558660/conservative-management-of-trigeminal-neuralgia-and-degenerative-cervical-myelopathy-a-case-report
#14
Eric Chun-Pu Chu, Jamir P Rissardo
It is hypothesized that degenerative cervical myelopathy (DCM) may induce or exacerbate trigeminal neuralgia (TN) through mechanisms such as direct compression of the spinal trigeminal tract, inflammation, or vascular issues, leading to ischemia within cervical segments C3-C4, where the spinal trigeminal nucleus extends. Here, we report the potential therapeutic impact of chiropractic treatment in a 55-year-old female with TN resistance to medical therapy and DCM. The patient received targeted chiropractic care, consisting of high-velocity, low-amplitude (HVLA) spinal manipulation of the C3-C7 and T1-T4 vertebral segments to address joint dysfunction, coupled with intermittent mechanical cervical traction for 20-minute sessions, and focused radial shockwave therapy aimed at myofascial trigger points within the trapezius and levator scapulae muscles...
February 2024: Curēus
https://read.qxmd.com/read/38557523/comparative-study-between-paracervical-block-and-non-steroidal-anti-inflammatory-drug-for-relief-of-pain-during-manual-vacuum-aspiration-procedure
#15
JOURNAL ARTICLE
R R Sarker, S A Begum, T Mahmud, Z Sultana, P A Parvin, M Faruq, A Khanom
The incidence of first trimester pregnancy loss is around 10.0-20.0% of registered pregnancies. Manual vacuum aspiration is a safe, effective and acceptable option of treatment for patients diagnosed with first trimester pregnancy loss. Main disadvantage of MVA is the pain caused by manipulation of the cervix, the uterine suction and the cervical dilatation. This study showed the way how the pain and discomfort might be reduced. This was a cross-sectional comparative study was conducted at the obstetrics and Gynecological Department of Sadar hospital, Manikganj, Bangladesh from January 2017 to December 2017...
April 2024: Mymensingh Medical Journal: MMJ
https://read.qxmd.com/read/38553028/a-retrospective-study-of-the-effects-of-uterine-manipulators-on-prognosis-in-patients-with-cervical-cancer
#16
JOURNAL ARTICLE
Xinmeng Guo, Enfeng Zhao, Zheng Guan, Weiping Li, Jinning Zhang, Shuang Tian, Yuanqing Yao
OBJECTIVE: This retrospective study investigated the effects of uterine manipulator use during minimally invasive radical hysterectomy on prognosis in patients with cervical cancer. METHODS: We collected clinical data on 762 patients with stage IA2 to IIB cervical cancer who underwent radical hysterectomy and pelvic lymphadenectomy in Chinese PLA General Hospital from 2009 to 2019. Kaplan-Meier analysis and log-rank tests were used to compare the 5-year overall survival rates between patients treated with and without a uterine manipulator...
March 2024: Journal of International Medical Research
https://read.qxmd.com/read/38552820/analgesia-efficacy-of-lidocaine-transfused-by-a-novel-disposable-injectable-cervical-dilator-during-intrauterine-device-removal-procedure-a-randomized-clinical-trial
#17
JOURNAL ARTICLE
Yahui Wang, Qianying Chen, Zhengnan Liu, Yun Chen, Yingling Zheng, Jialu Guo, Fan Zhou, Nengyuan Lv, Jianying Zhao, Siyi Shen, Qiaolei Yuan, Jinyi Tong
OBJECTIVE: The majority of intrauterine devices (IUDs) inserted in China are tailless, requiring intrauterine manipulations for removal and causing pain. This study aimed to investigate the analgesic efficacy of lidocaine injection into a novel disposable injectable cervical dilator for IUD removal procedures. STUDY DESIGN: A double-blinded, placebo-controlled, randomized clinical trial was conducted with women aged 18-65 years old requesting outpatient IUD removal...
March 27, 2024: Contraception
https://read.qxmd.com/read/38551917/comparative-effectiveness-of-cervical-vs-thoracic-spinal-thrust-manipulation-for-care-of-cervicogenic-headache-a-randomized-controlled-trial
#18
JOURNAL ARTICLE
Gopal Nambi, Mshari Alghadier, Mudathir Mohamedahmed Eltayeb, Osama R Aldhafian, Ayman K Saleh, Nesreen Alsanousi, Alaa Jameel A Albarakati, Mohamed A Omar, Mohamed Nagah Ahmed Ibrahim, Abdehamid A Attallah, Mohammed Abdelgwad Ismail, Mohamed Elfeshawy
BACKGROUND: There is ample evidence supporting the use of different manipulative therapy techniques for Cervicogenic Headache (CgH). However, no technique can be singled as the best available treatment for patients with CgH. Therefore, the objective of the study is to find and compare the clinical effects of cervical spine over thoracic spine manipulation and conventional physiotherapy in patients with CgH. DESIGN, SETTING, AND PARTICIPANTS: It is a prospective, randomized controlled study conducted between July 2020 and January 2023 at the University hospital...
2024: PloS One
https://read.qxmd.com/read/38550469/twists-and-turns-a-chiropractic-roller-coaster-experience-unraveling-the-intricacies-of-bilateral-vertebral-artery-dissection
#19
Satori Iwamoto, Megan D Hsu, An Phuc D Ta, Alexis Leo, Harrison Chu, Gary Chu
The primary insult in vertebral artery dissections (VADs) involves a tear in the vertebral artery intima, resulting in potential thrombus formation and an elevated risk of cerebrovascular events, such as stroke. Despite its relatively low overall incidence rate, VADs contribute to a significant proportion of ischemic strokes within the younger population. VAD has been associated with various risk factors including but not limited to neck trauma from chiropractic manipulation and significant neck movements. Our patient initially presented with a worsening occipital headache but was discharged due to the absence of any red-flag symptoms...
February 2024: Curēus
https://read.qxmd.com/read/38550104/retracted-clinical-efficacy-and-safety-of-three-dimensional-balanced-manipulation-in-the-treatment-of-cervical-spondylotic-radiculopathy-by-finite-element-analysis
#20
BioMed Research International
[This retracts the article DOI: 10.1155/2021/5563296.].
2024: BioMed Research International
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