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Cervical manipulation

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https://www.readbyqxmd.com/read/29322984/a-device-for-three-dimensional-quantitative-assessment-and-alignment-of-c1-2-vertebrae-during-posterior-distraction-and-fusion-technique-for-atlantoaxial-dislocation-and-or-basilar-invagination
#1
P B Karthik, Jayesh Sardhara, Nachiketa Tiwari, Sanjay Behari
The most common type of congenital C1-2 dislocation is a combined type in which atlanto-axial dislocation (AAD) and basilar invagination (BI) are often associated with a rotational dislocation and coronal tilt. An optimal surgical treatment involves reduction of AAD and BI with simultaneous correction of the rotation and coronal tilt to achieve an optimal cervical canal decompression, sagittal and coronal realignment and bony fusion. The most acceptable technique to facilitate this correction is the C1-C2 distraction technique, which is accomplished by the manual joint manipulation...
January 2018: Neurology India
https://www.readbyqxmd.com/read/29315578/hcn4-pacemaker-channels-attenuate-the-parasympathetic-response-and-stabilize-the-spontaneous-firing-of-sinoatrial-node
#2
Yuko Kozasa, Noriyuki Nakashima, Masayuki Ito, Taisuke Ishikawa, Hiroki Kimoto, Kazuo Ushijima, Naomasa Makita, Makoto Takano
The heart rate is dynamically controlled by the sympathetic and parasympathetic nervous systems that regulate the sinoatrial node (SAN). HCN4 pacemaker channels are well-known causative molecule of congenital sick sinus syndrome. Although HCN4 channels are activated by cAMP, the sympathetic response of SAN was preserved in the patients carrying loss-of-function mutations of HCN4 gene. In order to clarify the contribution of HCN4 channels in the autonomic regulation of SAN, we developed novel gain-of-function mutant mice in which expression level of HCN4 channels could be reversibly changed from zero to ∼3 times of that in wild type mice, using tetracycline trans-activator and tetracycline responsive element...
January 9, 2018: Journal of Physiology
https://www.readbyqxmd.com/read/29289803/application-of-a-rubber-band-with-hooks-on-both-ends-for-vagus-nerve-stimulator-implantation
#3
Hiroshi Hosoyama, Ryosuke Hanaya, Toshiaki Otsubo, Masanori Sato, Yumi Kashida, Sei Sugata, Masaya Katagiri, Koji Iida, Kazunori Arita
BACKGROUND: Vagus nerve stimulation (VNS) is a valuable therapeutic option for many types of drug-resistant epilepsy. Muscle hooks and carotid endarterectomy rings have been used for cervical delamination preceding the implantation of stimulation electrodes. The attachment on both sides of a rubber band of Kamiyama-style hanging needles, as are used for scalp and dural retraction during craniotomy, yields a useful tool for VNS implantation. Here we report our experience with this method...
December 28, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29276467/chiropractic-management-using-multimodal-therapies-on-2-pediatric-patients-with-constipation
#4
Madhu Mia Iyer, Evangelia Skokos, Denise Piombo
Objective: The purpose of this case report is to describe chiropractic management of 7-month-old male twins who had had constipation since birth. Clinical Features: Identical male twins presented with the chief complaint of constipation and bloating. Both patients were born premature after 29 weeks of gestation and had invasive abdominal surgeries in the right lower quadrant resulting in healed postsurgical scars. Patient A underwent ileostomy for a perforation in his ileum...
December 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29259395/cervical-spine-mechanism-for-reproduction-of-the-biomechanical-behaviours-of-the-human-neck-during-rotation-traction-manipulation
#5
Yuancan Huang, Shuai Li, Minshan Feng, Liguo Zhu
Rotation-traction (RT) manipulation is a commonly used physical therapy procedure in TCM (traditional Chinese medicine) for cervical spondylosis. This procedure temporarily separates the C3 and C4 cervical vertebrae from each other when a physician applies a jerky action while the neck is voluntarily turned by the patient to a specific position as instructed by the physician, where the cervical vertebrae are twisted and locked. However, a high rate of cervical injury occurs due to inexperienced physician interns who lack sufficient training...
2017: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29234493/what-are-the-risks-of-manual-treatment-of-the-spine-a-scoping-review-for-clinicians
#6
REVIEW
Gabrielle Swait, Rob Finch
Background: Communicating to patients the risks of manual treatment to the spine is an important, but challenging element of informed consent. This scoping review aimed to characterise and summarise the available literature on risks and to describe implications for clinical practice and research. Method: A methodological framework for scoping reviews was followed. Systematic searches were conducted during June 2017. The quantity, nature and sources of literature were described...
2017: Chiropractic & Manual Therapies
https://www.readbyqxmd.com/read/29234411/kinematics-analysis-of-cervical-rotation-traction-manipulation-measured-by-a-motion-capture-system
#7
Zhu Liguo, Feng Minshan, Yin Xunlu, Wang Shangquan, Yu Jie
Objectives: To analyze the kinematics of cervical rotation-traction manipulation (CRTM). Methods: An experimental study measuring the kinematics of CRTM was conducted. A total of 18 healthy volunteers participated in the study. A single manipulator operated the CRTM for all subjects. Motion capture technology was adopted to track the trajectory during the CRTM operation. Results: The manipulated side did not influence the cervical spine motion...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29229054/relationship-between-subjective-experience-of-individuals-practitioner-seniority-cavitation-occurrence-and-3-dimensional-kinematics-during-cervical-spine-manipulation
#8
Bernard Van Geyt, Pierre-Michel A Dugailly, Louis De Page, Veronique Feipel
OBJECTIVE: The purpose of this study was to assess individual subjective experience (ISE) of the recipients of a cervical manipulation and to analyze the influence of kinematics, cavitation occurrence, and practitioner seniority on individual experience. METHODS: Practitioners with different seniority (years of experience) manipulated 20 asymptomatic volunteers at C3 and C5 on both sides. Kinematics were recorded using a 3-dimensional electrogoniometer, and ISE data were gathered through a questionnaire to explore the subjects' experiences of manipulation in terms of tactile sensations, relaxation, perception of the task, and therapist handling...
November 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29228737/reduced-m6a-mrna-methylation-is-correlated-with-the-progression-of-human-cervical-cancer
#9
Xiuli Wang, Zenghui Li, Beihua Kong, Chen Song, Jianglin Cong, Jianqing Hou, Shaoguang Wang
The m6A mRNA methylation involves in mRNA splicing, degradation and translation. Recent studies have revealed that reduced m6A mRNA methylation might promote cancer development. However, the role of m6A mRNA methylation in cervical cancer development remains unknown. Therefore, we investigated the role of m6A methylation in cervical cancer in the current study. We first evaluated the m6A mRNA methylation level in 286 pairs of cervical cancer samples and their adjacent normal tissues by dot blot assay. Then the role of m6A on patient survival rates and cervical cancer progression were assessed...
November 17, 2017: Oncotarget
https://www.readbyqxmd.com/read/29228289/clinical-practice-guideline-for-physical-therapy-assessment-and-treatment-in-patients-with-nonspecific-neck-pain
#10
Jasper D Bier, Wendy G M Scholten-Peeters, J Bart Staal, Jan Pool, Maurits W van Tulder, Emmylou Beekman, Jesper Knoop, Guus Meerhoff, Arianne P Verhagen
The Royal Dutch Society for Physical Therapy (KNGF) issued a clinical practice guideline for physical therapists that addresses the assessment and treatment of patients with nonspecific neck pain, including cervical radiculopathy, in Dutch primary care. Recommendations were based on a review of published systematic reviews.During the intake, the patient is screened for serious pathologies and corresponding patterns. Patients with cervical radiculopathy can be included or excluded through corresponding signs and symptoms and possibly diagnostic tests (Spurling test, traction/distraction test, and Upper Limb Tension Test)...
December 4, 2017: Physical Therapy
https://www.readbyqxmd.com/read/29179871/modulation-of-antigen-presenting-cell-functions-during-chronic-hpv-infection
#11
REVIEW
Abate Assefa Bashaw, Graham R Leggatt, Janin Chandra, Zewen K Tuong, Ian H Frazer
High-risk human papillomaviruses (HR-HPV) infect basal keratinocytes, where in some individuals they evade host immune responses and persist. Persistent HR-HPV infection of the cervix causes precancerous neoplasia that can eventuate in cervical cancer. Dendritic cells (DCs) are efficient in priming/cross-priming antigen-specific T cells and generating antiviral and antitumor cytotoxic CD8+ T cells. However, HR-HPV have adopted various immunosuppressive strategies, with modulation of DC function crucial to escape from the host adaptive immune response...
December 2017: Papillomavirus Research
https://www.readbyqxmd.com/read/29157076/uhrf1-epigenetically-down-regulates-ubch8-to-inhibit-apoptosis-in-cervical-cancer-cells
#12
Qishu Zhang, Lijun Qiao, Xiao Wang, Changkuan Ding, Jason J Chen
UHRF1 (ubiquitin-like, containing PHD and RING finger domains 1) is an important epigenetic regulator that plays a part in DNA methylation, protein methylation and ubiquitination. It is also frequently overexpressed in many types of cancers, including cervical cancer, which is caused by human papillomavirus (HPV). In this study, we showed that UHRF1 was up-regulated in HPV oncogene E7 expressing cells and HPV-positive cervical cancer cells. We demonstrated that UHRF1 down-regulated the expression of UBE2L6 gene that encodes the ISG15-conjugating enzyme UbcH8...
November 20, 2017: Cell Cycle
https://www.readbyqxmd.com/read/29153924/considerations-to-improve-the-safety-of-cervical-spine-manual-therapy
#13
Nathan Hutting, Roger Kerry, Michel W Coppieters, Gwendolijne G M Scholten-Peeters
Manipulation and mobilisation of the cervical spine are well established interventions in the management of patients with headache and/or neck pain. However, their benefits are accompanied by potential, yet rare risks in terms of serious adverse events, including neurovascular insult to the brain. A recent international framework for risk assessment and management offers directions in the mitigation of this risk by facilitating sound clinical reasoning. The aim of this article is to critically reflect on and summarize the current knowledge about cervical spine manual therapy and to provide guidance for clinical reasoning for cervical spine manual therapy...
November 3, 2017: Musculoskeletal Science & Practice
https://www.readbyqxmd.com/read/29146991/klf5-promotes-cervical-cancer-proliferation-migration-and-invasion-in-a-manner-partly-dependent-on-tnfrsf11a-expression
#14
Dong Ma, Ling-Ya Chang, Shan Zhao, Jun-Jian Zhao, Yan-Jie Xiong, Fu-Yuan Cao, Lu Yuan, Qi Zhang, Xin-Yue Wang, Mei-Li Geng, Huan-Yu Zheng, Ou Li
Although the transcription factor Krüppel-like factor 5 (KLF5) plays important roles in both inflammation and cancer, the mechanism by which this factor promotes cervical carcinogenesis remains unclear. In this study, we demonstrated a potential role for tumour necrosis factor receptor superfamily member 11a (TNFRSF11a), the corresponding gene of which is a direct binding target of KLF5, in tumour cell proliferation and invasiveness. Coexpression of KLF5 and TNFRSF11a correlated significantly with tumorigenesis in cervical tissues (P < 0...
November 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29135458/immediate-effects-of-osteopathic-treatment-versus-therapeutic-exercise-on-patients-with-chronic-cervical-pain
#15
Xabier Galindez-Ibarbengoetxea, Igor Setuain, Robinson Ramírez-Velez, Lars L Andersen, Miriam González-Izal, Andoni Jauregi, Mikel Izquierdo
Context • Alternatives to medication for immediate pain relief are needed because long-term use of pain medication has been associated with adverse effects. High-velocity, low-amplitude (HVLA) manipulation techniques (MTs) and craniocervical flexion (CCF) exercises have been frequently used in the management of chronic cervical pain. Objective • The study intended to compare the immediate effects on pain of a treatment using HVLA manipulation versus one using a CCF exercise protocol. Design • The research team designed a single-blinded, randomized clinical trial...
November 14, 2017: Alternative Therapies in Health and Medicine
https://www.readbyqxmd.com/read/29097958/unresolved-congenital-torticollis-and-its-consequences-a-report-of-2-cases
#16
Mette Hobaek Siegenthaler
Objective: The purpose of this report was to describe the clinical presentation and case management of 2 children with congenital torticollis. Clinical Features: Two male children (ages 6 and 10 years) presented to a chiropractic clinic with a history of congenital torticollis. They showed signs and symptoms of postural deficiency and developmental delay: posterior plagiocephaly, facial scoliosis, head tilt, compensatory thoracic scoliosis, decreased range of motion in the cervical spine, palpable decreased segmental motion of the upper cervical spine, and an age-related delay in throwing and catching a ball and in one-leg standing...
September 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29093783/the-skipped-segment-screw-construct-an-alternative-to-conventional-lateral-mass-fixation-biomechanical-analysis-in-a-porcine-cervical-spine-model
#17
Kedar Prashant Padhye, Yuvaraja Murugan, Raunak Milton, N Arunai Nambi Raj, Kenny Samuel David
Study Design: Cadaveric biomechanical study. Purpose: We compared the "skipped segment screw" (SSS) construct with the conventional "all segment screw" (ASS) construct for cervical spine fixation in six degrees of freedom in terms of the range of motion (ROM). Overview of Literature: Currently, no clear guidelines are available in the literature for the configuration of lateral mass (LM) screwrod fixation for cervical spine stabilization. Most surgeons tend to insert screws bilaterally at all segments from C3 to C6 with the assumption that implants at every level will provide maximum stability...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29081738/interlimb-dynamic-after-unilateral-focal-lesion-of-the-cervical-dorsal-corticospinal-tract-with-endothelin-1
#18
Walther A Carvalho, Carlomagno P Bahia, Jéssica C Teixeira, Walace Gomes-Leal, Antonio Pereira
Handedness is one of the most recognized lateralized behavior in humans. Usually, it is associated with manual superiority regarding performance proficiency. For instance, more than 90% of the human population is considered more skilled with the right hand, which is controlled by the left hemisphere, than with the left. However, during the performance of bimanual tasks, the two hands usually assume asymmetric roles, with one hand acting on objects while the other provides support, stabilizing the object. Traditionally, the role of the two hands is viewed as fixed...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29079071/occult-spinal-cord-injury-after-blunt-force-trauma-in-a-patient-with-achondroplasia-a-case-report-and-review-of-trauma-management-strategy
#19
Martin Huecker, Zach Harris, Eric Yazel
BACKGROUND: Achondroplastic dwarfism is associated with anatomic abnormalities that can predispose to occult injury and challenges in trauma management. Airway anatomy is problematic due to macrocephaly, midface hypoplasia, and a narrow nasopharynx. Manipulation of the neck is very dangerous due to the high likelihood of preexisting cervicomedullary stenosis. Restrictive lung disease and obstructive sleep apnea may complicate respiratory status. Peripheral and central venous access can be difficult to obtain...
October 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29053390/exploring-the-teaching-and-learning-of-clinical-reasoning-risks-and-benefits-of-cervical-spine-manipulation
#20
Katie Yamamoto, Luca Condotta, Chloe Haldane, Sahar Jaffrani, Victoria Johnstone, Patrick Jachyra, Barbara E Gibson, Euson Yeung
The aim of this study was to examine how risks and benefits of cervical spine manipulation (CSM) were framed and discussed in the context of mentorship and their impact on the perception of safe practice of CSM in clinical physiotherapy settings. A multi-method qualitative approach was employed, including a document analysis of established educational guidelines, observations of mentoring sessions, and individual face-to-face interviews with five mentees in the process of learning CSM, and four mentors with Orthopedic Manual Physical Therapy (OMPT) certification...
February 2018: Physiotherapy Theory and Practice
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