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Muscle energy

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https://www.readbyqxmd.com/read/28230173/a-novel-physiological-role-for-cardiac-myoglobin-in-lipid-metabolism
#1
Ulrike B Hendgen-Cotta, Sonja Esfeld, Cristina Coman, Robert Ahrends, Ludger Klein-Hitpass, Ulrich Flögel, Tienush Rassaf, Matthias Totzeck
Continuous contractile activity of the heart is essential and the required energy is mostly provided by fatty acid (FA) oxidation. Myocardial lipid accumulation can lead to pathological responses, however the underlying mechanisms remain elusive. The role of myoglobin in dioxygen binding in cardiomyocytes and oxidative skeletal muscle has widely been appreciated. Our recent work established myoglobin as a protector of cardiac function in hypoxia and disease states. We here unravel a novel role of cardiac myoglobin in governing FA metabolism to ensure the physiological energy production through β-oxidation, preventing myocardial lipid accumulation and preserving cardiac functions...
February 23, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28228414/moderate-and-sustained-exercise-modulates-muscle-proteolytic-and-myogenic-markers-in-gilthead-sea-bream-sparus-aurata
#2
Emilio J Vélez, Sheida Azizi, Esmail Lutfi, Encarnación Capilla, Alberto Moya, Isabel Navarro, Jaume Fernández-Borràs, Josefina Blasco, Joaquim Gutiérrez
Swimming activity primarily accelerates growth in fish by increasing protein synthesis and energy efficiency. The role of muscle in this process is remarkable and especially important in teleosts, where muscle represents a high percentage of body weight, and by the continuous growth that many fish species present. The aim of this work was to characterize the effects of five weeks of moderate and sustained swimming in gene and protein expression of myogenic regulatory factors, proliferation markers and proteolytic molecules in two muscle regions (anterior and caudal) of gilthead sea bream fingerlings...
February 22, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28227820/evaluating-respiratory-muscle-activity-using-a-wireless-sensor-platform
#3
Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Luis Estrada, Abel Torres, Leonardo Sarlabous, Raimon Jane, Raimon Jane, Luis Estrada, Leonardo Sarlabous, Abel Torres
Wireless sensors are an emerging technology that allows to assist physicians in the monitoring of patients health status. This approach can be used for the non-invasive recording of the electrical respiratory muscle activity of the diaphragm (EMGdi). In this work, we acquired the EMGdi signal of a healthy subject performing an inspiratory load test. To this end, the EMGdi activity was captured from a single channel of electromyography using a wireless platform which was compared with the EMGdi and the inspiratory mouth pressure (Pmouth) recorded with a conventional lab equipment...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227641/optimization-of-an-unpowered-energy-stored-exoskeleton-for-patients-with-spinal-cord-injury
#4
Xinyu Guan, Linhong Ji, Rencheng Wang, Wenjie Huang, Xinyu Guan, Linhong Ji, Rencheng Wang, Wenjie Huang, Rencheng Wang, Xinyu Guan, Wenjie Huang, Linhong Ji
The paper describes a novel unpowered energy-stored exoskeleton (ES-EXO) for spinal cord injured patients in consideration of patients' characteristics and injured levels. It proposed a method to optimize the energy-stored element to decrease the hip joint moment in walking. EMG patterns, ground reaction force and motion data from one participant with complete spinal cord injury at T10 were recorded. A combined human-ES-EXO model was built and the stored-energy element including locations and stiffness of springs were optimized in AnyBody Modeling System...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227340/mechanomyography-signals-in-spastic-muscle-and-the-correlation-with-the-modified-ashworth-scale
#5
E L Santos, M C Santos, E Krueger, G N Nogueira-Neto, P Nohama, E L Santos, M C Santos, E Krueger, G N Nogueira-Neto, P Nohama, G N Nogueira-Neto, M C Santos, E Krueger, E L Santos, P Nohama
The modified Ashworth scale (MAS) is the most widely used measurement technique to assess levels of spasticity. In MAS, the evaluator graduates spasticity considering his/her subjective analysis of the muscular endurance during passive stretching. Therefore, it is a subjective scale. Mechanomyography (MMG) allows registering the vibrations generated by muscle contraction and stretching events that propagate through the tissue until the surface of the skin. With this in mind, this study aimed to investigate possible correlations between MMG signal and muscle spasticity levels determined by MAS...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227301/an-adapted-double-threshold-protocol-for-spastic-muscles
#6
Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima, Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima, Pedro M Vieira, Joao F Ferreira, Pedro R Gomes, Carlos S Lima
The onset of muscle contraction has been an important element in the understanding of human motor control system as well as in the development of medical devices. This task is problematic in the study of spasticity using surface Electromyography (sEMG). In fact, spasticity is characterized by involuntary muscle contractions that can be seen as both, a non-stationary background if they are weak or a severe non-stationary EMG signal if they are strong. In other hand, these sEMG signals present a very low signal to noise ratio, beyond the added noise that contaminates this signal...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226837/a-preliminary-evaluation-of-myoelectrical-energy-distribution-of-the-front-neck-muscles-in-pharyngeal-phase-during-normal-swallowing
#7
Mingxing Zhu, Wanzhang Yang, Oluwarotimi Williams Samuel, Yun Xiang, Jianping Huang, Haiqing Zou, Guanglin Li, Mingxing Zhu, Wanzhang Yang, Oluwarotimi Williams Samuel, Yun Xiang, Jianping Huang, Haiqing Zou, Guanglin Li, Wanzhang Yang, Yun Xiang, Guanglin Li, Haiqing Zou, Jianping Huang, Oluwarotimi Williams Samuel, Mingxing Zhu
Pharyngeal phase is a central hub of swallowing in which food bolus pass through from the oral cavity to the esophageal. Proper understanding of the muscular activities in the pharyngeal phase is useful for assessing swallowing function and the occurrence of dysphagia in humans. In this study, high-density (HD) surface electromyography (sEMG) was used to study the muscular activities in the pharyngeal phase during swallowing tasks involving three healthy male subjects. The root mean square (RMS) of the HD sEMG data was computed by using a series of segmented windows as myoelectrical energy...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224277/energy-metabolism-during-endurance-flight-and-the-post-flight-recovery-phase
#8
REVIEW
Susanne Jenni-Eiermann
Migrating birds are known to fly non-stop for thousands of kilometres without food or water intake and at a high metabolic rate thereby relying on energy stores which were built up preceding a flight bout. Hence, from a physiological point of view the metabolism of a migrant has to switch between an active fasting phase during flight and a fuelling phase during stopover. To meet the energetic and water requirements of endurance flight, migratory birds have to store an optimal fuel composition and they have to be able to quickly mobilize and deliver sufficient energy to the working flight muscles...
February 21, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28223503/mitochondrial-energy-deficiency-leads-to-hyperproliferation-of-skeletal-muscle-mitochondria-and-enhanced-insulin-sensitivity
#9
Ryan M Morrow, Martin Picard, Olga Derbeneva, Jeremy Leipzig, Meagan J McManus, Gilles Gouspillou, Sébastien Barbat-Artigas, Carlos Dos Santos, Russell T Hepple, Deborah G Murdock, Douglas C Wallace
Diabetes is associated with impaired glucose metabolism in the presence of excess insulin. Glucose and fatty acids provide reducing equivalents to mitochondria to generate energy, and studies have reported mitochondrial dysfunction in type II diabetes patients. If mitochondrial dysfunction can cause diabetes, then we hypothesized that increased mitochondrial metabolism should render animals resistant to diabetes. This was confirmed in mice in which the heart-muscle-brain adenine nucleotide translocator isoform 1 (ANT1) was inactivated...
February 21, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28219696/irisin-in-goldfish-carassius-auratus-effects-of-irisin-injections-on-feeding-behavior-and-expression-of-appetite-regulators-uncoupling-proteins-and-lipoprotein-lipase-and-fasting-induced-changes-in-fndc5-expression
#10
Zahndra Diann Butt, Jessica Dalton Hackett, Hélène Volkoff
Irisin is a peptide cleaved from the fibronectin type III domain containing protein 5 (FNDC5) gene that is secreted predominantly by muscle cells but also by other tissues including brain and intestine. In mammals, irisin has been shown to have thermogenic actions via the modulation of uncoupling proteins (UCPs) and to affect feeding and energy homeostasis via actions in brain, adipose tissue, liver, muscle and gastrointestinal tract. To examine the role of irisin on feeding and metabolism in fish, the effects of peripheral (intraperitoneal) injections of irisin on feeding behavior, glucose levels and the mRNA expressions of appetite regulators (cocaine and amphetamine regulated transcript CART, agouti related protein AgRP, orexin), UCPs and lipoprotein lipase LPL and brain factors (brain-derived neurotrophic factor , BDNF and tyrosine hydroxylase TH) were assessed in brain, white muscle and intestine...
February 17, 2017: Peptides
https://www.readbyqxmd.com/read/28219586/factors-associated-with-the-development-of-sarcopenia-in-kidney-transplant-recipients
#11
M Yanishi, Y Kimura, H Tsukaguchi, Y Koito, H Taniguchi, T Mishima, Y Fukushima, M Sugi, H Kinoshita, T Matsuda
INTRODUCTION: Sarcopenia is characterized by an involuntary loss of skeletal muscle mass, strength, and function. Previous studies suggest that it is generally associated with aging and chronic kidney diseases. The focus of this study was on the association between sarcopenia and pre-sarcopenia in kidney transplant recipients. METHODS: Fifty-one patients who underwent kidney transplantation at Kansai Medical University Hospital were enrolled, and their sarcopenia status was evaluated between April and July 2016...
March 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28219475/effects-of-in-ovo-feeding-of-creatine-pyruvate-on-the-hatchability-growth-performance-and-energy-status-in-embryos-and-broiler-chickens
#12
M M Zhao, T Gao, L Zhang, J L Li, P A Lv, L L Yu, F Gao, G H Zhou
The effects of in ovo feeding (IOF) of creatine pyruvate (CrPyr) on the hatchability, growth performance and energy status of embryos and broilers (Arbor Acres) were investigated. Five treatments were arranged as non-injected treatment (Control), 0.6 ml physiological saline (0.75%) injected treatment (Saline), and IOF treatments injected with 0.6 ml physiological saline (0.75%) containing 3, 6 or 12 mg CrPyr (CrPyr3, CrPyr6 or CrPyr12) into the amnion per fertile egg on day 17.5 of incubation. After hatching, 80 male chicks from each treatment with similar weight close to the average BW of their pooled group were selected and randomly assigned into eight replicates of 10 chicks each...
February 21, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28218490/comparative-effects-of-energy-restriction-and-resveratrol-intake-on-glycemic-control-improvement
#13
I Milton-Laskibar, L Aguirre, M T Macarulla, U Etxeberria, F I Milagro, J A Martínez, J Contreras, M P Portillo
Resveratrol (RSV) has been proposed as an energy restriction mimetic. This study aimed to compare the effects of RSV and energy restriction on insulin resistance induced by an obesogenic diet. Any additive effect of both treatments was also analyzed. Rats were fed a high-fat high-sucrose diet for 6 weeks. They were then distributed in four experimental groups which were either fed a standard control diet (C), or treated with RSV (30 mg/kg/d), or submitted to energy restriction (R, 15%), or treated with RSV and submitted to energy restriction (RR)...
February 20, 2017: BioFactors
https://www.readbyqxmd.com/read/28217967/mitochondrial-cristae-density-a-dynamic-entity-that-is-critical-for-energy-production-and-metabolic-power-in-skeletal-muscle
#14
Cameron F Leveille, John S Mikhaeil, Kelli Turner, Sebastian Silvera, Jennifer Wilkinson, Val A Fajardo
The mitochondrion is a double membrane organelle, consisting of an inner and an outer membrane. This topological organization contributes to its function of energy production, via the electron transport chain (ETC) This article is protected by copyright. All rights reserved.
February 20, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28215129/longitudinal-changes-in-anthropometrics-and-impact-on-self-reported-physical-function-after-traumatic-brain-injury
#15
Lee-Anne S Chapple, Adam M Deane, Lauren T Williams, Richard Strickland, Chris Schultz, Kylie Lange, Daren K Heyland, Marianne J Chapman
BACKGROUND AND AIMS: Patients admitted to the ICU with a traumatic brain injury (TBI) are at risk of muscle wasting but this has not been quantified. Our aims were to describe longitudinal changes in anthropometrical data, compare the accuracy of non-invasive methodologies to the validated dual-energy x-ray absorptiometry (DXA), and assess the relationships between anthropometrical data and self-reported physical function. METHODS: In a prospective observational study, we recruited patients admitted to the ICU with a moderate-to-severe TBI over 12 months...
March 2017: Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine
https://www.readbyqxmd.com/read/28214148/muscle-characteristics-only-partially-explain-color-variations-in-fresh-hams
#16
K Stufft, J Elgin, B Patterson, S K Matarneh, R Preisser, H Shi, E M England, T L Scheffler, E W Mills, D E Gerrard
Fresh hams display significant lean color variation that persists through further processing and contributes to a less desirable cured product. In an attempt to understand the underlying cause of this color disparity, we evaluated the differences in muscle characteristics and energy metabolites across semimembranosus (SM) muscles differing in color variation. The L* (lightness) and a* (redness) values were highest and lowest (P<0.001), respectfully in the most caudal aspects of the muscle while the ultimate pH was the lowest (P<0...
December 24, 2016: Meat Science
https://www.readbyqxmd.com/read/28211057/reproductive-energy-expenditure-and-changes-in-body-morphology-for-a-population-of-chinook-salmon-oncorhynchus-tshawytscha-with-a-long-distance-migration
#17
T E Bowerman, A Pinson-Dumm, C A Peery, C C Caudill
Energetic demands of a long freshwater migration, extended holding period, gamete development and spawning were evaluated for a population of stream-type Chinook salmon Oncorhynchus tshawytscha. Female and male somatic mass decreased by 24 and 21%, respectively, during migration and by an additional 18 and 12% during holding. Between freshwater entry and death after spawning, females allocated 14% of initial somatic energy towards gonad development and 78% for metabolism (46, 25 and 7% during migration, holding and spawning, respectively)...
February 16, 2017: Journal of Fish Biology
https://www.readbyqxmd.com/read/28209382/err%C3%AE-a-junior-orphan-with-a-senior-role-in-metabolism
#18
REVIEW
Jagannath Misra, Don-Kyu Kim, Hueng-Sik Choi
Estrogen-related receptor (ERR)γ is an orphan nuclear hormone receptor that belongs to the ERR subfamily of transcription factors. No endogenous ligand has been identified to date. ERRγ possesses ligand-independent transcriptional activity that is regulated by co-regulator interactions, and post-translational modifications (PTMs). Recent data from animal models have established ERRγ as a crucial mediator of multiple endocrine and metabolic signals. ERRγ plays important roles in pathological conditions such as insulin resistance, alcoholic liver injury, and cardiac hypertrophy, and controls energy metabolism in the heart, skeletal muscle, and pancreatic β cells...
February 13, 2017: Trends in Endocrinology and Metabolism: TEM
https://www.readbyqxmd.com/read/28207859/differential-effects-of-silencing-crustacean-hyperglycemic-hormone-gene-expression-on-the-metabolic-profiles-of-the-muscle-and-hepatopancreas-in-the-crayfish-procambarus-clarkii
#19
Wenfeng Li, Kuo-Hsun Chiu, Yi-Chun Tien, Shih-Fu Tsai, Li-Jane Shih, Chien-Hsun Lee, Jean-Yves Toullec, Chi-Ying Lee
In order to functionally characterize the metabolic roles of crustacean hyperglycemic hormone (CHH), gene expression of CHH in the crayfish (Procambarus clarkii) was knocked down by in vivo injection of CHH double-stranded RNA (dsRNA), followed by metabolomic analysis of 2 CHH target tissues (the muscle and hepatopancreas) using nuclear magnetic resonance spectroscopy. Compared to the levels in untreated and saline-injected (SAI) animals, levels of CHH transcript, but not those of molt-inhibiting hormone (a CHH-family peptide), in the eyestalk ganglia of CHH dsRNA-injected (DSI) animals were significantly decreased at 24, 48, and 72 hour post injection (hpi), with concomitant changes in levels of CHH peptide in the sinus gland (a neurohemal organ) and hemolymph...
2017: PloS One
https://www.readbyqxmd.com/read/28207742/narciclasine-attenuates-diet-induced-obesity-by-promoting-oxidative-metabolism-in-skeletal-muscle
#20
Sofi G Julien, Sun-Yee Kim, Reinhard Brunmeir, Joanna R Sinnakannu, Xiaojia Ge, Hongyu Li, Wei Ma, Jadegoud Yaligar, Bhanu Prakash Kn, Sendhil S Velan, Pia V Röder, Qiongyi Zhang, Choon Kiat Sim, Jingyi Wu, Marta Garcia-Miralles, Mahmoud A Pouladi, Wei Xie, Craig McFarlane, Weiping Han, Feng Xu
Obesity develops when caloric intake exceeds metabolic needs. Promoting energy expenditure represents an attractive approach in the prevention of this fast-spreading epidemic. Here, we report a novel pharmacological strategy in which a natural compound, narciclasine (ncls), attenuates diet-induced obesity (DIO) in mice by promoting energy expenditure. Moreover, ncls promotes fat clearance from peripheral metabolic tissues, improves blood metabolic parameters in DIO mice, and protects these mice from the loss of voluntary physical activity...
February 2017: PLoS Biology
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