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https://www.readbyqxmd.com/read/29044122/wind-loads-and-competition-for-light-sculpt-trees-into-self-similar-structures
#1
Christophe Eloy, Meriem Fournier, André Lacointe, Bruno Moulia
Trees are self-similar structures: their branch lengths and diameters vary allometrically within the tree architecture, with longer and thicker branches near the ground. These tree allometries are often attributed to optimisation of hydraulic sap transport and safety against elastic buckling. Here, we show that these allometries also emerge from a model that includes competition for light, wind biomechanics and no hydraulics. We have developed MECHATREE, a numerical model of trees growing and evolving on a virtual island...
October 18, 2017: Nature Communications
https://www.readbyqxmd.com/read/29043762/food-deserts-in-winnipeg-canada-a-novel-method-for-measuring-a-complex-and-contested-construct
#2
Joyce Slater, Stefan Epp-Koop, Megan Jakilazek, Chris Green
INTRODUCTION: "Food deserts" have emerged over the past 20 years as spaces of concern for communities, public health authorities and researchers because of their potential negative impact on dietary quality and subsequent health outcomes. Food deserts are residential geographic spaces, typically in urban settings, where low-income residents have limited or no access to retail food establishments with sufficient variety at affordable cost. Research on food deserts presents methodological challenges including retail food store identification and classification, identification of low-income populations, and transportation and proximity metrics...
October 2017: Health Promotion and Chronic Disease Prevention in Canada
https://www.readbyqxmd.com/read/29043347/zinc-ing-it-out-zinc-homeostasis-mechanisms-and-their-impact-on-the-pathogenesis-of-human-pathogen-group-a-streptococcus
#3
REVIEW
Nishanth Makthal, Muthiah Kumaraswami
Group A Streptococccus (GAS) is a major human pathogen that causes significant morbidity and mortality. Zinc is an essential trace element required for GAS growth, however, zinc can be toxic at excess concentrations. The bacterial strategies to maintain zinc sufficiency without incurring zinc toxicity play a crucial role in host-GAS interactions and have a significant impact on GAS pathogenesis. The host deploys nutritional immune mechanisms to retard GAS growth by causing either zinc deprivation or zinc poisoning...
October 18, 2017: Metallomics: Integrated Biometal Science
https://www.readbyqxmd.com/read/29043081/effects-of-phospho-and-calciotropic-hormones-on-electrolyte-transport-in-the-proximal-tubule
#4
REVIEW
Justin J Lee, Allein Plain, Megan R Beggs, Henrik Dimke, R Todd Alexander
Calcium and phosphate are critical for a myriad of physiological and cellular processes within the organism. Consequently, plasma levels of calcium and phosphate are tightly regulated. This occurs through the combined effects of the phospho- and calciotropic hormones, parathyroid hormone (PTH), active vitamin D 3, and fibroblast growth factor 23 (FGF23). The organs central to this are the kidneys, intestine, and bone. In the kidney, the proximal tubule reabsorbs the majority of filtered calcium and phosphate, which amounts to more than 60% and 90%, respectively...
2017: F1000Research
https://www.readbyqxmd.com/read/29042024/the-role-of-the-ltb4-blt1-axis-in-chemotactic-gradient-sensing-and-directed-leukocyte-migration
#5
REVIEW
Bhagawat C Subramanian, Ritankar Majumdar, Carole A Parent
Directed leukocyte migration is a hallmark of inflammatory immune responses. Leukotrienes are derived from arachidonic acid and represent a class of potent lipid mediators of leukocyte migration. In this review, we summarize the essential steps leading to the production of LTB4 in leukocytes. We discuss the recent findings on the exosomal packaging and transport of LTB4 in the context of chemotactic gradients formation and regulation of leukocyte recruitment. We also discuss the dynamic roles of the LTB4 receptors, BLT1 and BLT2, in mediating chemotactic signaling in leukocytes and contrast them to other structurally related leukotrienes that bind to distinct GPCRs...
October 2017: Seminars in Immunology
https://www.readbyqxmd.com/read/29040641/emerging-models-on-the-regulation-of-intercellular-transport-by-plasmodesmata-associated-callose
#6
Sam Amsbury, Philip Kirk, Yoselin Benitez-Alfonso
The intercellular transport of molecules through membranous channels that traverse the cell walls-so-called plasmodesmata-is of fundamental importance for plant development. Regulation of plasmodesmata aperture (and transport capacity) is mediated by changes in the flanking cell walls, mainly via the synthesis/degradation (turnover) of the (1,3)-β-glucan polymer callose. The role of callose in organ development and in plant environmental responses is well recognized, but detailed understanding of the mechanisms regulating its accumulation and its effects on the structure and permeability of the channels is still missing...
October 5, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29040241/barriers-to-implementation-of-recommendations-for-transport-of-children-in-ground-ambulances
#7
Rashida H Woods, Manish Shah, Cara Doughty, Anthony Gilchrest
OBJECTIVES: The National Highway Traffic Safety Administration (NHTSA) released draft recommendations in 2010 on the safe transport of children in ground ambulances. The purpose of this study was to assess awareness of these guidelines among emergency medical service (EMS) agencies and to identify implementation barriers. METHODS: We conducted a cross-sectional, anonymous online survey of 911-responding, ground transport EMS agencies in Texas. Demographics, modes of transport based on case scenarios, and barriers to implementation were assessed...
October 16, 2017: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29039670/proton-exchange-induced-configuration-rearrangement-in-a-poly-ionic-liquid-solution-a-nmr-study
#8
Haijin Zhu, Hengrui Yang, Jiaye Li, Kristine J Barlow, Lingxue Kong, David Mecerreyes, Douglas R Macfarlane, Maria Forsyth
Polymeric ionic liquids have emerged recently as a promising alternative to traditional polymers as the polymer electrolyte membrane materials of choice because of their strongly decoupled dynamics between the polymer backbone and the counter ions. Knowledge of proton exchange and transport mechanism in such materials is of critical importance to the design and development of new poly(ionic liquid) materials with improved electrochemical properties. Our NMR results show that the proton exchange between the labile proton of the diethylmethylammonium (NH122) cation and H2O molecules is accompanied by a concerted configuration rearrangement of the ammonium...
October 17, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29037602/hiv-sti-prevention-among-heterosexually-active-black-adolescents-with-mental-illnesses-focus-group-findings-for-intervention-development
#9
Bridgette M Brawner, Loretta Sweet Jemmott, Gina Wingood, Janaiya Reason, Niya Mack
Heterosexually active Black adolescents with mental illnesses are at increased risk for sexually transmitted infections (STIs), including HIV. However, few HIV/STI prevention interventions exist for this demographic. We held seven focus groups (N = 33) to elucidate social, cultural, and psychological factors that influence HIV/STI risk-related sexual behaviors in this understudied population. Seven themes emerged: (a) Blackness and media portrayals, (b) Blackness as a source of cultural resilience and pride, (c) psychosocial determinants of condom use, (d) consequences of engaging in sexual activity, (e) attitudes and beliefs toward sexual behaviors, (f) benefits of sexual activity, and (g) coping mechanisms...
September 28, 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29037033/carboxymethylcellulose-mediates-the-transport-of-carbon-nanotubes-magnetite-nanohybrid-aggregates-in-water-saturated-porous-media
#10
Dengjun Wang, Chang Min Park, Arvid Masud, Nirupam Aich, Chunming Su
Carbon-metal oxide nanohybrids (NHs) are increasingly recognized as the next-generation, promising group of nanomaterials for solving emerging environmental issues and challenges. This research, for the first time, systematically explored the transport and retention of carbon nanotubes-magnetite (CNT-Fe3O4) NH aggregates in water-saturated porous media under environmentally relevant conditions. A macromolecule modifier, carboxymethylcellulose (CMC) was employed to stabilize the NHs. Our results show that transport of the magnetic CNT-Fe3O4 NHs was lower than that of non-magnetic CNT due to larger hydrodynamic sizes of NHs (induced by magnetic attraction) and size-dependent retention in porous media...
October 17, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29036640/toxicokinetics-of-the-synthetic-cathinone-%C3%AE-pyrrolidinohexanophenone
#11
Yuji Fujita, Toshinori Mita, Kiyotaka Usui, Yoshito Kamijo, Satoshi Kikuchi, Makoto Onodera, Yasuhisa Fujino, Yoshihiro Inoue
Synthetic cathinones inhibit monoamine transporters, such as serotonin, norepinephrine, and dopamine transporters, and act on the central nervous system via increasing synaptic concentrations of monoamines. These compounds, which are highly addictive and potentially poisonous, are new psychoactive substances. In this study, we investigated the toxicokinetics of the synthetic cathinone, α-pyrrolidinohexanophenone (α-PHP), and assessed the relationship between the toxicokinetics and the long-term clinical symptoms induced by α-PHP in a male patient...
September 28, 2017: Journal of Analytical Toxicology
https://www.readbyqxmd.com/read/29036463/multiple-links-between-shade-avoidance-and-auxin-networks
#12
María José Iglesias, Romina Sellaro, Matias D Zurbriggen, Jorge José Casal
Auxin has emerged as a key player in the adjustment of plant morphology to the challenge imposed by variable environmental conditions. Shade-avoidance responses, including the promotion of stem and petiole growth, leaf hyponasty, and the inhibition of branching, involve an intimate connection between light and auxin signalling. Low activity of photo-sensory receptors caused by the presence of neighbouring vegetation enhances the activity of PHYTOCHROME INTERACTING FACTORs (PIFs), which directly promote the expression of genes involved in auxin biosynthesis, conjugation, transport, perception, and signalling...
September 27, 2017: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29035632/a-multi-objective-optimization-model-and-orthogonal-design-based-hybrid-heuristic-algorithm-for-regional-urban-mining-management-problems
#13
Hao Wu, Zhong Wan
In this paper, a multi-objective mixed-integer piecewise nonlinear programming model (MOMIPNLP) is built to formulate the management problem of urban mining system, where the decision variables are associated with buy-back pricing, choices of sites, transportation planning and adjustment of production capacity. Different from the existing approaches, the social negative effect, generated from structural optimization of the recycling system, is minimized in our model, as well as the total recycling profit and utility from environmental improvement are jointly maximized...
October 16, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29034682/modulated-transport-behavior-of-two-dimensional-electron-gas-at-ni-doped-laalo3-srtio3-heterointerfaces
#14
Hong Yan, Zhaoting Zhang, Shuanhu Wang, Hongrui Zhang, Chang-Le Chen, Kexin Jin
Modulating transport behaviors of two-dimensional electron gas is of critical importance for applications of the next-generation multifunctional oxide electronics. In this study, transport behaviors of LaAlO3/SrTiO3 heterointerfaces modified through the Ni dopant and the light irradiation have been investigated. Through the Ni dopant, the resistances increase significantly and a resistance upturn phenomenon is observed at T < 40 K. Under a 360 nm light irradiation, the interfaces exhibit a persistent photoconductivity and a suppressed Kondo effect at low temperature due to the increased mobility measured through a photo-Hall method...
October 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29034073/unmet-goals-in-the-treatment-of-acute-myocardial-infarction-review
#15
REVIEW
Alejandro Farah, Alejandro Barbagelata
Reperfusion therapy decreases myocardium damage during an acute coronary event and consequently mortality. However, there are unmet needs in the treatment of acute myocardial infarction, consequently mortality and heart failure continue to occur in about 10% and 20% of cases, respectively. Different strategies could improve reperfusion. These strategies, like generation of warning sign recognition and being initially assisted and transferred by an emergency service, could reduce the time to reperfusion. If the first electrocardiogram is performed en route, it can be transmitted and interpreted in a timely manner by a specialist at the receiving center, bypassing community hospitals without percutaneous coronary intervention capabilities...
2017: F1000Research
https://www.readbyqxmd.com/read/29033968/dancing-with-hormones-a-current-perspective-of-nitrate-signaling-and-regulation-in-arabidopsis
#16
REVIEW
Peizhu Guan
In nature and agriculture, nitrate availability is a main environmental cue for plant growth, development and stress responses. Nitrate signaling and regulation are hence at the center of communications between plant intrinsic programs and the environment. It is also well known that endogenous phytohormones play numerous critical roles in integrating extrinsic cues and intrinsic responses, regulating and refining almost all aspects of plant growth, development and stress responses. Therefore, interaction between nitrate and phytohormones, such as auxins, cytokinins, abscisic acid, gibberellins, and ethylene, is prevalent...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29033796/laminar-and-cellular-distribution-of-monoamine-receptors-in-rat-medial-prefrontal-cortex
#17
REVIEW
Noemí Santana, Francesc Artigas
The prefrontal cortex (PFC) is deeply involved in higher brain functions, many of which are altered in psychiatric conditions. The PFC exerts a top-down control of most cortical and subcortical areas through descending pathways and is densely innervated by axons emerging from the brainstem monoamine cell groups, namely, the dorsal and median raphe nuclei (DR and MnR, respectively), the ventral tegmental area and the locus coeruleus (LC). In turn, the activity of these cell groups is tightly controlled by afferent pathways arising from layer V PFC pyramidal neurons...
2017: Frontiers in Neuroanatomy
https://www.readbyqxmd.com/read/29032875/ventilator-use-by-emergency-medical-services-during-911-calls-in-the-united-states
#18
Mazen El Sayed, Hani Tamim, Aurelie Mailhac, Mann N Clay
BACKGROUND: Emergency and transport ventilators use in the prehospital field is not well described. This study examines trends of ventilator use by EMS agencies during 911 calls in the United States and identifies factors associated with this use. METHODS: This retrospective study used four consecutive releases of the US National Emergency Medical Services Information System (NEMSIS) public research dataset (2011-2014) to describe scene EMS activations (911 calls) with and without reported ventilator use...
October 6, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29032703/the-use-of-telepsychiatry-to-provide-cost-efficient-care-during-pediatric-mental-health-emergencies
#19
John F Thomas, Douglas K Novins, Patrick W Hosokawa, Christina A Olson, Dru Hunter, Alison S Brent, Gerard Frunzi, Anne M Libby
OBJECTIVE: This study evaluated a videoconference-based psychiatric emergency consultation program (telepsychiatry) at geographically dispersed emergency department (ED) sites that are part of the network of care of an academic children's hospital system. The study compared program outcomes with those of usual care involving ambulance transport to the hospital for in-person psychiatric emergency consultation prior to disposition to inpatient care or discharge home. METHODS: This study compared process outcomes in a cross-sectional, pre-post design at five network-of-care sites before and after systemwide implementation of telepsychiatry consultation in 2015...
October 16, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29032497/emerging-mosquito-species-in-germany-a-synopsis-after-6%C3%A2-years-of-mosquito-monitoring-2011-2016
#20
Helge Kampen, Astrid Schuhbauer, Doreen Walther
Globalisation and climate change are the main drivers of invasion of non-endemic regions by mosquitoes. Mass transportation of people, animals and goods facilitate accidental long-distance displacement while climate warming supports active spread and establishment of thermophilic species. In the framework of a mosquito-monitoring programme, eight non-indigenous culicid species have been registered in Germany since 2011, with four of them being more or less efficient vectors of disease agents and another four now considered established...
October 14, 2017: Parasitology Research
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