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https://www.readbyqxmd.com/read/29474373/hospitalization-mortality-and-associated-risk-factors-in-patients-with-polymyositis-and-dermatomyositis-a-retrospective-case-control-study
#1
Chanyuan Wu, Qian Wang, Linrong He, Enhao Yang, Xiaofeng Zeng
BACKGROUND: Polymyositis and dermatomyositis (PM/DM) are systemic autoimmune diseases with multiple organ involvements that manifest as muscular and cutaneous disorders, interstitial lung disease (ILD) and malignancies. However, information concerning the outcomes and associated factors for PM/DM patients who are hospitalized is limited. METHODS: We retrospectively reviewed the medical charts of PM/DM patients admitted to a Chinese tertiary referral hospital (Peking Union Medical College Hospital, PUMCH) from 2008 to 2014...
2018: PloS One
https://www.readbyqxmd.com/read/29471588/attenuated-effectiveness-of-tumor-necrosis-factor-inhibitors-for-anti-human-t-lymphotropic-virus-type-1-antibody-positive-rheumatoid-arthritis
#2
Takahisa Suzuki, Shoichi Fukui, Kunihiko Umekita, Junya Miyamoto, Masataka Umeda, Ayako Nishino, Akitomo Okada, Tomohiro Koga, Shin-Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Keita Fujikawa, Toshiyuki Aramaki, Akinari Mizokami, Naoki Matsuoka, Yukitaka Ueki, Katsumi Eguchi, Shuntaro Sato, Toshihiko Hidaka, Tomoki Origuchi, Akihiko Okayama, Atsushi Kawakami, Hideki Nakamura
OBJECTIVES: We evaluated the effectiveness of tumor necrosis factor (TNF) inhibitors for the treatment of human T-lymphotropic virus type 1 (HTLV-I)-positive rheumatoid arthritis (RA) patients in an HTLV-I endemic area. METHODS: We conducted an observational study of 585 RA patients for whom TNF inhibitors were newly introduced as a first biologic disease-modifying antirheumatic drug (bDMARD) in an HTLV-I endemic area in southwestern Japan. RESULTS: Fifty patients (8...
February 22, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29471485/trabecular-bone-score-as-an-assessment-tool-to-identify-the-risk-of-osteoporosis-in-axial-spondyloarthritis-a-case-control-study
#3
Kwi Young Kang, Hye Yeon Goo, Sung-Hwan Park, Yeon Sik Hong
Objectives: To compare the trabecular bone score (TBS) between patients with axial spondyloarthritis (axSpA) and matched normal controls and identify risk factors associated with a low TBS. Methods: TBS and BMD were assessed in the two groups (axSpA and control) using DXA. Osteoporosis risk factors and inflammatory markers were also assessed. Disease activity and radiographic progression in the sacroiliac joint and spine were evaluated in the axSpA group. Multivariate linear regression analysis was performed to identify risk factors associated with TBS...
March 1, 2018: Rheumatology
https://www.readbyqxmd.com/read/29471252/relationship-between-monocytes-to-lymphocytes-ratio-and-axial-spondyloarthritis
#4
Yukai Huang, Weiming Deng, Shaoling Zheng, Fan Feng, Zhixiang Huang, Qidang Huang, Xin Guo, Zhengping Huang, Xuechang Huang, Xia Pan, Tianwang Li
BACKGROUND: Axial spondyloarthritis (axSpA) is a progressive, chronic, inflammatory skeletal disorder affecting the spine and sacroiliac joints. Many studies have shown that neutrophils, lymphocytes, monocytes, platelets, and red blood cells (RBCs) play important roles in the inflammatory process of axSpA. Neutrophils to lymphocytes ratio (NLR) and red blood cell distribution width (RDW) have been reported to be simple and inexpensive markers to indicate the disease activity of axSpA...
February 19, 2018: International Immunopharmacology
https://www.readbyqxmd.com/read/29469036/incomplete-kawasaki-disease-in-an-infant-with-cholangitis-post-kasai-surgery-for-biliary-atresia
#5
Naman S Shetty, Ira Shah
Kawasaki's disease (KD) is a systemic vasculitis often seen with viral and bacterial infections. Cholangitis is a known complication in biliary atresia patients post Kasai Portoenterostomy (KP). However KD, in a biliary atresia patient post KP has not been previously reported. A 1 years old girl who had previously undergone a KP for BA, presented with cholangitis which was presumed to be caused by a previous enterobacter infection that she had 2 months ago. However, on treating the cholangitis, the patient developed fever again after ten days which persisted even after changing the antibiotics...
March 1, 2018: Annals of Hepatology
https://www.readbyqxmd.com/read/29469014/effect-of-mineral-status-and-glucocorticoid-use-on-bone-mineral-density-in-patients-with-crohn-s-disease
#6
Nayane R Pierote, Amanda F Braz, Susy L Barros, José M Moita Neto, José Miguel L Parente, Maria da Cruz M Silva, Mayara S Beserra, Nina Rosa M Soares, Dilina N Marreiro, Nadir do Noscimento Nogueira
OBJECTIVES: Crohn's disease (CD) is a condition that is characterized by chronic inflammation. The presence of multifactorial pathogenesis that results from inflammation is associated with low micronutrient consumption and glucocorticoid use, which may be related to bone health. This study aimed to evaluate the relationship between dietary mineral intake and glucocorticoid use in bone mineral density (BMD) in patients with CD. METHODS: A cross-sectional study of 62 patients with CD ages 20 y to 40 y measured their macro- and micronutrient intake with a 3-d food record...
November 27, 2017: Nutrition
https://www.readbyqxmd.com/read/29468833/machine-learning-integration-of-rheumatoid-arthritis-synovial-histology-and-rnaseq-data-identifies-three-disease-subtypes
#7
Dana E Orange, Phaedra Agius, Edward F DiCarlo, Nicolas Robine, Heather Geiger, Jackie Szymonifka, Michael McNamara, Ryan Cummings, Kathleen M Andersen, Serene Mirza, Mark Figgie, Lionel Ivashkiv, Alessandra B Pernis, Caroline Jiang, Mayu Frank, Robert Darnell, Nithya Lingampali, Robinson William, Ellen Gravallese, Vivian P Bykerk, Susan M Goodman, Laura T Donlin
OBJECTIVE: We sought to refine histologic scoring of rheumatoid arthritis synovial tissue by training with gene expression data and machine learning. METHODS: Twenty histologic features were assessed on 129 synovial tissue samples. Consensus clustering was performed on gene expression data from a subset of 45 synovial samples. Support vector machine learning was used to predict gene expression subtypes using histology data as input. Corresponding clinical data were compared across subtypes...
February 22, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29466947/stroke-as-an-atypical-initial-presentation-of-giant-cell-arteritis
#8
Tharsika Kuganesan, Allen R Huang
BACKGROUND: Giant cell arteritis (GCA) is an immune mediated inflammatory disease of medium and large arteries which afflicts older people. The classical presentation features include: headache, visual disturbances, and jaw claudication. Patients diagnosed with GCA have also been observed to be at higher risk for the subsequent development of strokes. CASE PRESENTATION: We describe a case of an 84-year old right-handed man who presented to hospital with dysarthria, dysphagia, right-sided facial drop, a history of generalized weakness and multiple falls...
February 21, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29465582/successfully-treating-hand-primary-tuberculous-synovitis-by-synovectomy-combined-antituberculous-therapy-a-case-report
#9
Tao Wang, Gang Zhao, Yong-Jun Rui, Jing-Yi Mi
RATIONALE: Primary tuberculous infection in hand and wrist is a rare disease. Few articles reported on hand primary tuberculous synovitis. PATIENT CONCERNS: A 68-year-old Chinese male, without history of tuberculosis (TB), had complained of pain and swelling in right palm and little finger for 3 months. Patient came to our hospital on 9th Oct 2016. X-ray just showed soft tissue swelling in little finger. Magnetic resonance imaging (MRI) showed synovitis around flexor tendon of little finger, volar palm, and carpal tunnel...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29465563/non-hodgkin-lymphoma-diagnostic-and-prognostic-particularities-in-children-a-series-of-case-reports-and-a-review-of-the-literature-care-compliant
#10
Cristina Oana Mărginean, Lorena Elena Meliţ, Emoke Horvath, Horea Gozar, Mihaela Ioana Chinceşan
RATIONALE: Non-Hodgkin lymphoma remains an unpredictable condition in pediatric patients. PATIENT CONCERNS: Our first case describes an 8-year-old boy with a history of iron deficiency anemia, admitted in our clinic for recurrent abdominal pain, weight loss, loss of appetite, diarrheic stools, and fever. The second case also describes an 8-year-old boy admitted for abdominal pain and vomiting. The 3rd case refers to a 4 years and 10 months old boy admitted in our clinic with abdominal pain and loss of appetite, who was initially admitted in the Pediatrics Surgery Clinic with the suspicion of appendicitis...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29465542/the-small-bowel-diseases-detected-by-capsule-endoscopy-in-patients-with-chronic-abdominal-pain-a-retrospective-study
#11
Libin Huang, Zhiyin Huang, Yang Tai, Pu Wang, Bing Hu, Chengwei Tang
Chronic abdominal pain (CAP) remains a particular challenge because of its complicated causes, especially when the disorders involve the small bowel, where it is quite difficult to intubate the flexible endoscopes. This study was to investigate the small bowel diseases detected by capsule endoscopy (CE) in CAP patients to evaluate the role of CE on CAP, and analyzed the relationship among the clinical characteristics of CAP patients and the positive rates of CE findings to search for the indications of CE for CAP patients...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29465367/proprotein-convertase-enzyme-furin-is-upregulated-in-primary-sj%C3%A3-gren-s-syndrome
#12
Noora Ranta, Atte Valli, Anna Grönholm, Olli Silvennoinen, Pia Isomäki, Marko Pesu, Marja Pertovaara
OBJECTIVES: The proprotein convertase enzyme FURIN is a critical regulator of the anti-inflammatory TGFβ-1 cytokine and peripheral immune tolerance. In T cells, FURIN is co-regulated with IFN-γ and thus highly expressed in T helper 1 type cells. Previous studies have demonstrated that FURIN is upregulated in inflammatory conditions, including atherosclerosis, rheumatoid arthritis and systemic lupus erythematosus. Here, we evaluated the levels of FURIN in the plasma and peripheral blood mononuclear cells (PBMCs) of patients with primary Sjögren's syndrome (pSS) and in healthy controls...
February 21, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29465111/crp-and-esr-in-giant-cell-arteritis
#13
A Waller, A M Jawad
No abstract text is available yet for this article.
September 2017: Journal of the Royal College of Physicians of Edinburgh
https://www.readbyqxmd.com/read/29464237/magneto-structural-correlations-in-oxalate-bridged-sr-ii-cr-iii-coordination-polymers-structure-magnetization-x-band-and-high-field-esr-studies
#14
L Androš Dubraja, M Jurić, J Popović, D Pajić, Y Krupskaya, V Kataev, B Bűchner, D Žilić
The results of high-field electron spin resonance (HF-ESR) spectroscopy on the title 1D coordination polymers at frequencies up to 415 GHz, supported by X-ray diffraction, thermal, magnetic susceptibility, and X-band (10 GHz) ESR studies, are presented. The heterometallic compounds {SrCr2 (phen)2 (C2 O4 )4 }·H2 O (SrCrPhen) and {SrCr2 (bpy)2 (C2 O4 )4 (H2 O)}·5H2 O (SrCrBpy) (phen = 1,10-phenanthroline, bpy = 2,2'-bipyridine) were synthesized. Structural analysis revealed double oxalate-bridged zigzag Sr-Cr chains while magnetic susceptibility studies showed paramagnetic behaviour of the complexes...
February 21, 2018: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/29464211/probing-quantum-coherence-in-single-atom-electron-spin-resonance
#15
Philip Willke, William Paul, Fabian D Natterer, Kai Yang, Yujeong Bae, Taeyoung Choi, Joaquin Fernández-Rossier, Andreas J Heinrich, Christoper P Lutz
Spin resonance of individual spin centers allows applications ranging from quantum information technology to atomic-scale magnetometry. To protect the quantum properties of a spin, control over its local environment, including energy relaxation and decoherence processes, is crucial. However, in most existing architectures, the environment remains fixed by the crystal structure and electrical contacts. Recently, spin-polarized scanning tunneling microscopy (STM), in combination with electron spin resonance (ESR), allowed the study of single adatoms and inter-atomic coupling with an unprecedented combination of spatial and energy resolution...
February 2018: Science Advances
https://www.readbyqxmd.com/read/29460148/impact-of-vitamin-d-deficiency-on-clinical-parameters-in-treatment-na%C3%A3-ve-rheumatoid-arthritis-patients
#16
Yang Liu, Hongyan Wen
OBJECTIVE: To determine if patients with rheumatoid arthritis (RA) are at risk of vitamin D deficiency and whether the levels of vitamin D are correlated with clinical parameters in RA. METHODS: A total of 280 treatment-naïve RA patients, and 140 age- and sex-matched healthy volunteers were enrolled. Serum levels of 1,25-dihydroxycholecalciferol (1,25(OH)2 D3 ), the active form of vitamin D, were measured by enzyme-linked immunosorbent assay (ELISA). Concentrations of 1,25(OH)2 D3 less than 25 ng/mL were defined as insufficient...
February 19, 2018: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/29460129/esr-paper-on-structured-reporting-in-radiology
#17
REVIEW
(no author information available yet)
Structured reporting is emerging as a key element of optimising radiology's contribution to patient outcomes and ensuring the value of radiologists' work. It is being developed and supported by many national and international radiology societies, based on the recognised need to use uniform language and structure to accurately describe radiology findings. Standardisation of report structures ensures that all relevant areas are addressed. Standardisation of terminology prevents ambiguity in reports and facilitates comparability of reports...
February 19, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29457273/clinical-risk-factors-for-early-seizure-recurrence-in-dogs-hospitalized-for-seizure-evaluation
#18
M Kwiatkowska, A Tipold, E Huenerfauth, A Pomianowski
BACKGROUND: Epileptic seizures are a common cause for neurological evaluations in dogs. HYPOTHESIS/OBJECTIVES: To determine the timing, frequency, and risk factors for early seizure recurrence (ESR) among dogs admitted to the hospital for seizure evaluation and to facilitate rapid decision making about whether dogs should be placed in the intensive care unit (ICU) or day ward. ANIMALS: Nine-hundred twenty-two dogs referred for seizure investigation; 214 patients were included...
February 18, 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29455479/-clinical-application-of-modified-inverted-l-shape-incision-by-extraperitoneal-approach-to-lumbosacral-tuberculosis
#19
Shi-Yuan Shi, Sheng-Ping Hu, Jun Fei, Zhen Lai, Gui-He Hang
OBJECTIVE: To explore the clinical effects of one-stage posterior transpedicular screw system internal fixation combined with anterior debridement and bone grafting with modified inverted L-shape incision by extraperitoneal approach in treating multiple lumbosacral tuberculosis. METHODS: The clinical data of 15 patients with multiple lumbosacral tuberculosis underwent operation from February 2008 to December 2014 were retrospectively analyzed. There were 9 males and 6 females with an average of (47...
September 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29454800/remarkable-improved-electro-fenton-efficiency-by-electric-field-induced-catalysis-of-ceo-2
#20
Wei Ren, Diyong Tang, Meiyu Huang, Jie Sun, Kangle Lv
In this study, we designed a novel combined electro-Fenton system for the treatment of wastewater containing biological recalcitrant using electric-field-induced ceria (CeO2 ) as the synergistic catalysts. It was found that by applying this CeO2 electro-Fenton system, the current efficiency improved from 74.49% to 109.82% within 2.5 min; the removal efficiency for dimethyl phthalate (DMP) increased from 85.5% to 94.9% within 20 min; and the mineralization rate increased from 76.01% to 93.58% after 120 min. The effects of parameters such as the applied potential, electrolyte, and concentration of Fe2+ on the current efficiency were systematically studied...
February 10, 2018: Journal of Hazardous Materials
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