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https://www.readbyqxmd.com/read/28338307/evaluation-of-the-spies%C3%A2-modalities-image-quality
#1
Esteban Emiliani, Michele Talso, Mohammed Baghdadi, Aarón Barreiro, Andrea Orosa, Pol Serviàn, Pavel Gavrilov, Silvia Proietti, Olivier Traxer
INTRODUCTION: The Spies™ system (Karl-Storz®) was introduced into digital ureteroscopy to improve endoscopic vision. To date, there is no data to either indicate which of the Spies modalities is better for improving diagnosis and treatment procedures, nor to compare the modalities in terms of image quality. The aim of this study was to evaluate and compare the image quality of five Spies™ modalities (SM) to the standard white light in an in-vitro model. MATERIALS AND METHODS: Two standardized grids and 3 stones of different composition were recorded in white light and the 5SM (Clara, Chroma, Clara+Chroma), Spectra A and B) using 4 standardized aqueous scenarios...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28295721/endometrial-biopsy-in-bos-indicus-beef-heifers
#2
O Ramirez-Garzon, N Satake, R E Lyons, J Hill, M K Holland, M McGowan
An endometrial biopsy allows for a comprehensive assessment of the uterine environment of a breeding female. Although routine in mares, devices used for endometrial biopsies are impracticable in heifers due to the size and structure of the cervix. This report describes the use of a human bronchoscopy biopsy device (Karl Storz(®) 10366L) for collection of endometrial biopsies in Bos indicus beef heifers. The Storz(®) device is smaller and thinner and enabled the collection of an endometrial biopsy in 86% of heifers (n = 44/51)...
March 11, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28289086/sgrt-a-small-protein-that-packs-a-sweet-punch
#3
Medha Raina, Gisela Storz
The SgrS small RNA (sRNA) has been shown to protect against elevated levels of glucose phosphate by regulating the stability and translation of mRNAs encoding proteins involved in sugar transport and catabolism. The sRNA also was known to encode a protective 43 amino acid protein, SgrT, but little was known about its mechanism of action. In this issue, Lloyd et al. use cell biological and genetic approaches to demonstrate that the small protein interacts with the PtsG importer to block glucose transport by this phosphotransferase system and promote utilization of non-preferred carbon sources to maintain growth during glucose-phosphate stress...
March 13, 2017: Journal of Bacteriology
https://www.readbyqxmd.com/read/28270694/acinar-cell-plasticity-and-development-of-pancreatic-ductal-adenocarcinoma
#4
REVIEW
Peter Storz
Acinar cells in the adult pancreas show high plasticity and can undergo transdifferentiation to a progenitor-like cell type with ductal characteristics. This process, termed acinar-to-ductal metaplasia (ADM), is an important feature facilitating pancreas regeneration after injury. Data from animal models show that cells that undergo ADM in response to oncogenic signalling are precursors for pancreatic intraepithelial neoplasia lesions, which can further progress to pancreatic ductal adenocarcinoma (PDAC). As human pancreatic adenocarcinoma is often diagnosed at a stage of metastatic disease, understanding the processes that lead to its initiation is important for the discovery of markers for early detection, as well as options that enable an early intervention...
March 8, 2017: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28263385/intraoperative-near-infrared-fluorescence-imaging-targeting-folate-receptors-identifies-lung-cancer-in-a-large-animal-model
#5
Jane J Keating, Jeffrey J Runge, Sunil Singhal, Sarah Nims, Ollin Venegas, Amy C Durham, Gary Swain, Shuming Nie, Philip S Low, David E Holt
BACKGROUND: Complete tumor resection is the most important predictor of patient survival with non-small cell lung cancer. Methods for intraoperative margin assessment after lung cancer excision are lacking. This study evaluated near-infrared (NIR) intraoperative imaging with a folate-targeted molecular contrast agent (OTL0038) for the localization of primary lung adenocarcinomas, lymph node sampling, and margin assessment. METHODS: Ten dogs with lung cancer underwent either video-assisted thoracoscopic surgery or open thoracotomy and tumor excision after an intravenous injection of OTL0038...
May 15, 2017: Cancer
https://www.readbyqxmd.com/read/28248013/-molecular-mechanisms-of-individual-platelet-reactivity-in-hematuria-secondary-to-lithotripsy
#6
E F Barinov, T A Tverdokhleb, A N Kravchenko, A O Balykina, N A Cherkasova
AIM: To investigate the mechanisms of individual platelet reactivity to ADP and adrenaline associated with the variability of hematuria after lithotripsy in patients with chronic obstructive pyelonephritis (COPN). MATERIALS AND METHODS: The study included 41 COPN patients admitted to the Department of Urology for lithotripsy (LT). The contact ultrasonic LT was performed using the Karl Storz Calcuson Ultrasonic Lithotripsy System. Postoperative hematuria was assessed by microscopic red blood cell count...
November 2016: Urologii︠a︡
https://www.readbyqxmd.com/read/28221157/minimally-invasive-pcnl-mip
#7
Stefano Paolo Zanetti, Luca Boeri, Andrea Gallioli, Michele Talso, Emanuele Montanari
Miniaturized percutaneous nephrolithotomy (mini-PCNL) has increased in popularity in recent years and is now widely used to overcome the therapeutic gap between conventional PCNL and less-invasive procedures such as shock wave lithotripsy (SWL) or flexible ureterorenoscopy (URS) for the treatment of renal stones. However, despite its minimally invasive nature, the superiority in terms of safety, as well as the similar efficacy of mini-PCNL compared to conventional procedures, is still under debate. The aim of this chapter is to present one of the most recent advancements in terms of mini-PCNL: the Karl Storz "minimally invasive PCNL" (MIP)...
January 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28201714/stability-mediated-epistasis-restricts-accessible-mutational-pathways-in-the-functional-evolution-of-avian-hemoglobin
#8
Amit Kumar, Chandrasekhar Natarajan, Hideaki Moriyama, Christopher C Witt, Roy E Weber, Angela Fago, Jay F Storz
No abstract text is available yet for this article.
February 13, 2017: Molecular Biology and Evolution
https://www.readbyqxmd.com/read/28168139/video-laryngoscopy-vs-direct-laryngoscopy-in-teaching-neonatal-endotracheal-intubation-a-simulation-based-study
#9
Srikumar Nair, Eric J Thomas, Lakshmi Katakam
BACKGROUND: Neonatal endotracheal intubation is a life-saving procedural skill where best practices have been developed from expert opinion. Few empirical studies have examined how this skill should be taught. OBJECTIVE: To determine whether a video laryngoscope (VL) assisted intubation training curriculum compared to a traditional direct laryngoscope (DL) assisted curriculum improves neonatal intubation performance of novice intubators in a simulated setting. METHODS: A randomized trial of novice intubators was conducted at the University of Texas-Houston from 6/2013-8/2013...
January 6, 2017: Curēus
https://www.readbyqxmd.com/read/28154929/first-intraoperative-experience-with-three-dimensional-3d-high-definition-hd-nasal-endoscopy-for-lacrimal-surgeries
#10
Mohammad Javed Ali, Milind N Naik
The aim of this study is to report our preliminary experiences with regard to safety and feasibility of three-dimensional (3D) endoscopic lacrimal surgeries with a recently launched latest generation 3D endoscope. A 4-mm rigid three-dimensional (3D) endoscope (TIPCAM 1S 3D ORL(R), Karl Storz, Tuttlingen, Germany) was used. Fifteen patients who underwent various endoscopic lacrimal procedures by a single surgeon (MJA) were included. The procedures included probing with nasolacrimal intubation, cruciate marsupialization of intranasal cysts for congenital dacryoceles, powered endoscopic dacryocystorhinostomy, post-operative stent removal with ostium granuloma excision...
February 2, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28149570/optimizing-the-exposure-in-minimally-invasive-mitral-surgery-a-new-left-atrial-retractor-system
#11
Ernesto Greco, David Rose, Francesco Irace, Giacomo Frati
Optimal exposure of the mitral valve is paramount in minimally invasive surgery (MIS) and a prerequisite for successful mitral valve repair or replacement. We report the concept of a new left atrial retractor (Karl Storz GmbH, Tuttlingen, Germany) dedicated to MIS. The effectiveness of the device was evaluated in a prospective series of 40 patients successfully operated at our institution.
December 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28094826/response-to-dittrich-et-al-non-embryo-destructive-extraction-of-pluripotent-embryonic-stem-cells-overlooked-legal-prohibitions-professional-legal-consequences-and-inconsistencies-in-patent-law
#12
REVIEW
T Faltus, U Storz
The publication of "Non-embryo-destructive Extraction of Pluripotent Embryonic Stem Cells: Implications for Regenerative Medicine and Reproductive Medicine" by Dittrich et al. in Geburtshilfe und Frauenheilkunde 2015; 75: 1239-1242 1 describes various possibilities which could result from the non-embryo-destructive extraction of embryonic stem cells from human blastocysts. But implementing this method is more problematic, both legally and ethically, than the authors have represented it to be and is illegal in Germany...
December 2016: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28077391/acclimation-to-hypoxia-increases-carbohydrate-use-during-exercise-in-high-altitude-deer-mice
#13
Daphne S Lau, Alex D Connaty, Sajeni Mahalingam, Nastashya Wall, Zachary A Cheviron, Jay F Storz, Graham R Scott, Grant B McClelland
The low O2 experienced at high altitude is a significant challenge to effective aerobic locomotion, as it requires sustained tissue O2 delivery in addition to the appropriate allocation of metabolic substrates. Here, we tested whether high- and low-altitude deer mice (Peromyscus maniculatus) have evolved different acclimation responses to hypoxia with respect to muscle metabolism and fuel use during submaximal exercise. Using F1 generation high- and low-altitude deer mice that were born and raised in common conditions, we assessed 1) fuel use during exercise, 2) metabolic enzyme activities, and 3) gene expression for key transporters and enzymes in the gastrocnemius...
March 1, 2017: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology
https://www.readbyqxmd.com/read/28073204/who-apparently-more-spends-in-reality-spends-less-spending-a-little-more-for-the-rental-of-the-extracorporeal-lithotripter-can-save-a-lot-about-the-days-of-hospitalization-for-urinary-stones
#14
Giuseppe Albino, Francesco Albergo
OBJECTIVE: The right to health (according to the Article 32 of the Italian Republic Constitution) is financially conditioned; for this reason the National Health System (NHS) has the objective of rationalize health expenditure according to the criteria of efficiency, effectiveness and economy. This paper is an example of rationalization concerning the extracorporeal shock wave lithotripsy (ESWL). MATERIALS AND METHODS: Hospital admissions for urinary stones were taken into account...
December 30, 2016: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28067954/elemental-variability-in-the-coralline-alga-lithophyllum-yemenense-as-an-archive-of-past-climate-in-the-gulf-of-aden-nw-indian-ocean
#15
Annalisa Caragnano, Daniela Basso, David Storz, Dorrit E Jacob, Federica Ragazzola, Francesca Benzoni, Eric Dutrieux
This study presents the first algal thallus (skeleton) archive of Asian monsoon strength and Red Sea influence in the Gulf of Aden. Mg/Ca, Li/Ca, and Ba/Ca were measured in Lithophyllum yemenense from Balhaf (Gulf of Aden) using laser ablation inductively coupled plasma mass spectrometry, and Mg/Ca ratio oscillation was used to reconstruct the chronology (34 y). Oscillations of element rates corresponding to the algal growth between 1974 and 2008 were compared with recorded climate and oceanographic variability...
January 9, 2017: Journal of Phycology
https://www.readbyqxmd.com/read/28011978/what-is-the-best-tool-for-transanal-endoscopic-microsurgery-tem-a-case-matched-study-in-74-patients-comparing-a-standard-platform-and-a-disposable-material
#16
Diane Mege, Valérie Bridoux, Léon Maggiori, Jean-Jacques Tuech, Yves Panis
PURPOSE: Transanal endoscopic microsurgery (TEM) is the gold standard for local excision of rectal lesions, but no study exists concerning the best material. The objective was to compare TEM using a disposable material vs a standard platform through a case-matched study. METHODS: Patients who underwent TEM for rectal neoplasms were identified from prospective databases in two tertiary referral centers and matched according to four criteria (sex, tumor location, size, distance from the anal verge): TEM using a disposable material (GelPoint Applied®; group A) and TEM using a standard TEO® platform (Karl Storz, Tuttlingen, Germany; group B)...
December 24, 2016: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28009138/intracorporeal-hybrid-single-port-vs-conventional-laparoscopic-appendectomy-in-children
#17
Paul Anthony Karam, Amy Hiuser, David Magnuson, Federico Gian Filippo Seifarth
Transumbilical laparoscopic assisted appendectomy combines laparoscopic single port dissection with open appendectomy after exteriorization of the appendix through the port site. Compared to the conventional three-port approach, this technique provides an alternative with excellent cosmetic outcome. We developed a safe and effective technique to perform an intracorporeal single port appendectomy, using the same laparoscope employed in the extracorporeal procedure. Retrospective review of 71 consecutively performed intracorporeal single port appendectomies and 30 conventional three-port appendectomies in children 6 to 17 years of age...
December 20, 2016: La Pediatria Medica e Chirurgica: Medical and Surgical Pediatrics
https://www.readbyqxmd.com/read/27981926/stone-free-rate-after-extracorporeal-shockwave-lithotripsy-in-the-management-of-pediatric-renal-stones-in-lower-pole-and-other-locations-a-comparative-study
#18
Nadeem Iqbal, Shujah Muhammad, Warda Zafar, Ravale Tashfeen, Javaria Faiz, Aisha Hasan, Ijaz Hussain, Saeed Akhter
OBJECTIVE: To determine a difference in the stone-free-rate among different renal locations in children after extracorporeal shockwave lithotripsy (ESWL). STUDY DESIGN: A descriptive study. PLACE AND DURATION OF STUDY: Urology Department, Shifa International Hospital, Islamabad, Pakistan, from January 2007 to June 2015. METHODOLOGY: The study included children who underwent ESWL, divided into three groups based on location of stones in kidney as group A (lower pole stones), group B (upper and mid pole stones) and group C (renal pelvis stone), respectively...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/27981862/evaluation-of-a-novel-single-use-flexible-ureteroscope
#19
Joanne Dale, Adam G Kaplan, Daniela Radvak, Richard Shin, Anika Ackerman, Tony Chen, Charles D Scales, Michael N Ferrandino, Walter Neal Simmons, Glenn M Preminger, Michael E Lipkin
INTRODUCTION: A novel single-use flexible ureteroscope promises the optical characteristics and maneuverability of a reusable fourth-generation flexible ureteroscope. In this study, the LithoVue Single-Use Digital flexible ureteroscope was directly compared with contemporary reusable flexible ureteroscopes, with regard to optics, deflection, and irrigation flow. METHODS: Three flexible ureteroscopes such as the LithoVue (Single Use; Boston Scientific), Flex-Xc (Karl Storz, Germany), and Cobra (Richard Wolf, Germany) were assessed in vitro for image resolution, distortion, color representation, grayscale imaging, field of view, and depth of field...
March 2, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/27976982/patent-eligibility-of-stem-cells-in-europe-where-do-we-stand-after-8-years-of-case-law
#20
Ulrich Storz, Timo Faltus
Since 2006, some of the highest ranking European Courts have issued decisions related to the patent eligibility of human embryonic stem cells. The question of patent eligibility of human embryonic stem cells remains, however, still erratic, at least in some aspects. This article will give a short comprehensive overview of the case history, and discuss questions still unsolved.
January 2017: Regenerative Medicine
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