keyword
MENU ▼
Read by QxMD icon Read
search

Direct flow Medical

keyword
https://www.readbyqxmd.com/read/27903217/rational-drug-discovery-of-hcv-helicase-inhibitor-improved-docking-accuracy-with-multiple-seedings-of-autodock-vina-and-in-situ-minimization
#1
SeeKhai Lim, Rozana Othman, Rohana Yusof, ChoonHan Heh
BACKGROUND: Hepatitis C is a significant cause for end-stage liver diseases and liver transplantation which affects approximate 3% of the global populations. Despite the present of several direct antiviral agents in the treatment of hepatitis C, the standard treatment for HCV is accompanied by several drawbacks such as adverse side effects, high pricing of medications and the rapid emerging rate of resistant HCV variants. OBJECTIVES: To discover potential inhibitors for HCV helicase through an optimized in silico approach...
November 30, 2016: Current Computer-aided Drug Design
https://www.readbyqxmd.com/read/27903057/spatial-analysis-and-prediction-of-the-flow-of-patients-to-public-health-centres-in-a-middle-sized-spanish-city
#2
Isabel Ramos, Juan J Cubillas, Francisco R Feito, Tomas Ureña
Human and medical resources in the Spanish primary health care centres are usually planned and managed on the basis of the average number of patients in previous years. However, sudden increases in patient demand leading to delays and slip-ups can occur at any time without warning. This paper describes a predictive model capable of calculating patient demand in advance using geospatial data, whose values depend directly on weather variables and location of the health centre people are assigned to. The results obtained here show that outcomes differ from one centre to another depending on variations in the variables measured...
November 21, 2016: Geospatial Health
https://www.readbyqxmd.com/read/27879381/pediatric-prolonged-mechanical-ventilation-considerations-for-definitional-criteria
#3
REVIEW
Michaël Sauthier, Louise Rose, Philippe Jouvet
A 2005 consensus conference led by the National Association for Medical Direction of Respiratory Care (NAMDRC) defined prolonged mechanical ventilation (PMV) for adults as invasive and/or noninvasive mechanical ventilation (NIV) for ≥21 consecutive days for ≥6 h/d. In children, no such consensus definition exists. This results in substantial variability in definitional criteria, making study of the impact and outcomes of PMV across and within settings problematic. The objective of this work was to identify how PMV for children and neonates is described in the literature and to outline pediatric/neonatal considerations related to PMV, with the goal of proposing a pediatric/neonatal adaptation to the NAMDRC definition...
November 22, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27879074/s1-guidelines-on-the-diagnosis-and-treatment-of-scabies-short-version
#4
Cord Sunderkötter, Hermann Feldmeier, Regina Fölster-Holst, Bertram Geisel, Sabine Klinke-Rehbein, Alexander Nast, Sandra Philipp, Bernhardt Sachs, Julia Stingl, Johanna Stoevesandt, Henning Hamm
The goals of this German guideline are the improvement of diagnosis and therapy of scabies, the implementation of a coordinated action in outbreaks of scabies, and the control of this infestation in large migration or refugee flows.Sarcoptes scabiei var. hominis is transmitted by direct skin-to-skin contact of sufficient duration. The infectivity of female mites when removed from patients does not exceed 48 hours at room temperature (21°C) and relative humidity of 40-80%. The risk of infection rises proportionally to the number of mites on the skin and is particularly high in crusted scabies...
November 2016: Journal der Deutschen Dermatologischen Gesellschaft, Journal of the German Society of Dermatology: JDDG
https://www.readbyqxmd.com/read/27876391/critical-evaluation-of-monitoring-strategy-for-the-multi-residue-determination-of-90-chiral-and-achiral-micropollutants-in-effluent-wastewater
#5
Bruce Petrie, Kathryn Proctor, Jane Youdan, Ruth Barden, Barbara Kasprzyk-Hordern
It is essential to monitor the release of organic micropollutants from wastewater treatment plants (WWTPs) for developing environmental risk assessment and assessing compliance with legislative regulation. In this study the impact of sampling strategy on the quantitative determination of micropollutants in effluent wastewater was investigated. An extended list of 90 chiral and achiral micropollutants representing a broad range of biological and physico-chemical properties were studied simultaneously for the first time...
November 19, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27852249/assessment-of-work-related-asthma-prevalence-control-and-severity-protocol-of-a-field-study
#6
Hermine Mével, Valérie Demange, Emmanuelle Penven, Christian Trontin, Pascal Wild, Christophe Paris
BACKGROUND: There are still uncertainties regarding the respective prevalence, diagnosis and management of occupational asthma (OA) and work-exacerbated asthma (WEA). There is as yet no standardized methodology to differentiate their diagnosis. A proper management of both OA and WEA requires tools for a good phenotyping in terms of control, severity and quality of life in order to propose case-specific therapeutical and preventive measures. Moreover, there is a lack of knowledge concerning their actual costs...
November 16, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27836148/volumetric-shrinkage-and-film-thickness-of-cementation-materials-for-veneers-an-in%C3%A2-vitro-3d-microcomputed-tomography-analysis
#7
Camila S Sampaio, João Malta Barbosa, Eduardo Cáceres, Lindiane C Rigo, Paulo G Coelho, Estevam A Bonfante, Ronaldo Hirata
STATEMENT OF PROBLEM: Few studies have investigated the volumetric polymerization shrinkage and film thickness of the different cementation techniques used to cement veneers. PURPOSE: The purpose of this in vitro study was to evaluate the volumetric polymerization shrinkage (VS) and film thickness (FT) of various cementation techniques through 3-dimensional (3D) microcomputed tomography (μCT). MATERIAL AND METHODS: Forty-eight artificial plastic maxillary central incisors with standard preparations for veneers were provided by a mannequin manufacturer (P-Oclusal) and used as testing models with the manufacturer's plastic veneers...
November 8, 2016: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/27752312/improving-emergency-department-flow-through-optimized-bed-utilization
#8
Lucas Brien Chartier, Licinia Simoes, Meredith Kuipers, Barb McGovern
Over the last decade, patient volumes in the emergency department (ED) have grown disproportionately compared to the increase in staffing and resources at the Toronto Western Hospital, an academic tertiary care centre in Toronto, Canada. The resultant congestion has spilled over to the ED waiting room, where medically undifferentiated and potentially unstable patients must wait until a bed becomes available. The aim of this quality improvement project was to decrease the 90th percentile of wait time between triage and bed assignment (time-to-bed) by half, from 120 to 60 minutes, for our highest acuity patients...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27751762/short-term-angiotensin-subtype-1-receptor-blockade-does-not-alter-the-circulatory-responses-to-sympathetic-nervous-system-modulation-in-healthy-volunteers-before-and-during-sevoflurane-anesthesia-results-of-a-pilot-study
#9
Shahbaz R Arain, Julie K Freed, Jutta Novalija, Paul S Pagel, Thomas J Ebert
OBJECTIVE: The mechanism of perioperative hypotension in patients taking an angiotensin-receptor blocker up to the time of surgery remains unclear. This study tested the hypothesis that short-term angiotensin-receptor blocker treatment attenuated the sympathetic and vascular responses to autonomic stimuli in volunteers undergoing anesthesia. DESIGN: Randomized, crossover, blinded, pilot design. SETTING: Zablocki Veterans Affairs Medical Center, Milwaukee, WI...
December 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27743797/enhanced-plasmid-loss-in-bacterial-populations-exposed-to-the-antimicrobial-compound-irgasan-delivered-from-interpenetrating-polymer-network-silicone-hydrogels
#10
Leise Riber, Mette Burmølle, Martin Alm, Stefan M Milani, Peter Thomsen, Lars H Hansen, Søren J Sørensen
The spread of antimicrobial resistance, usually mediated by horizontal transfer of plasmids, limits the options of treating bacterial infections and thereby poses a crucial human health problem. The disturbance of plasmid stability within bacterial species in clinical environments serves as a novel strategy to reduce the development and dissemination of antibiotic resistance. We tested the ability of irgasan to destabilize plasmids from Escherichia coli K-12 cells when added directly into liquid growth medium at concentrations below levels of marked bacterial growth inhibition, or when released into liquid growth medium from irgasan-impregnated Interpenetrating Polymer Network (IPN) silicone hydrogel objects, a novel technology developed as drug-delivery platform...
October 12, 2016: Plasmid
https://www.readbyqxmd.com/read/27739170/trans-catheter-aortic-valve-implantation-with-the-direct-flow-medical-prosthesis-single-center-short-term-clinical-and-echocardiographic-outcomes
#11
Stephan Kische, Giuseppe D'Ancona, Hüseyin U Agma, Gihan El-Achkar, Martin Dißmann, Jasmin Ortak, Hüseyin Ince
OBJECTIVES: To analyze our single center experience with the Direct Flow Medical (DFM). BACKGROUND: The DFM has been recently introduced to the market and large real world experiences are lacking. METHODS: A total of 126 patients with severe aortic valve stenosis (AVS) were treated by the same team from March 2013 to May 2015. Device success and procedural safety were classified, according to valve academic research consortium (VARC) criteria, for the entire cohort, including patients treated in the early phases of our learning curve...
October 14, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27739165/transcatheter-aortic-valve-implantation-with-the-direct-flow-medical-prosthesis-impact-of-native-aortic-valve-calcification-degree-on-outcomes
#12
Giuseppe D'Ancona, Hüseyin U Agma, Hüseyin Ince, Gihan El-Achkar, Martin Dißmann, Jasmin Ortak, Stephan Kische
OBJECTIVES: We present our single center experience with the direct flow medical (DFM) prosthesis addressing the impact of native aortic valve (AV) calcification degree on outcomes. BACKGROUND: The DFM® has been introduced for transcatheter aortic valve implantation (TAVI). The valve has a nonmetallic and inflatable support structure. METHODS: Patients were divided in two groups according to preoperative cardiac computed tomography (CT): group I moderate calcification and group II heavy calcification of the total AV area...
October 14, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27711966/an-argument-for-fewer-clinical-trials
#13
Kirstin Borgerson
The volume of clinical research is increasing exponentially-far beyond our ability to process and absorb the results. Given this situation, it may be beneficial to consider reducing the flow at its source. In what follows, I will motivate and critically evaluate the following proposal: researchers should conduct fewer clinical trials. More specifically, I c onsider whether researchers should be permitted to conduct only clinical research of very high quality and, in turn, whether research ethics committees (RECs) should prohibit all other, lower-quality research, even when it might appear to meet some minimal ethical standard...
November 2016: Hastings Center Report
https://www.readbyqxmd.com/read/27699852/true-morphology-of-mitral-regurgitant-flow-assessed-by-three-dimensional-transesophageal-echocardiography
#14
Martin Lombardero, Ruth Henquin, Gabriel Perea, Mariana Corneli, Carlos Izurieta
INTRODUCTION: Quantification of mitral regurgitation (MR) by two-dimensional (2D) transthoracic echocardiography (TTE) is based on the analysis of the proximal flow convergence (PFC) and the "vena contracta" (VC). This method assumes geometries and can be misleading. In contrast, three-dimensional (3D) echocardiography directly measures flow volumes and does not assume geometries, which allows for more accurate MR evaluation. AIMS: To report the 3D transesophageal echocardiography (3DTEE) feasibility for MR quantification and evaluate its concordance with 2D echo...
October 4, 2016: Echocardiography
https://www.readbyqxmd.com/read/27692474/lateral-based-anterior-vaginal-wall-flap-in-the-treatment-of-female-urethral-stricture-efficacy-and-safety
#15
Jesús Romero-Maroto, Lidia Verdú-Verdú, Luis Gómez-Pérez, Carla Pérez-Tomás, Juan-José Pacheco-Bru, Ana López-López
BACKGROUND: Female urethral stricture is a rare condition. Different types of urethroplasty have been described. However, high quality studies are sparse. The most common technique used-the Blandy's technique-has resulted in our cases in a retrusive meatus and an inward urinary stream. OBJECTIVE: To show the efficacy and safety of an alternative vaginal wall flap urethroplasty. DESIGN, SETTING, AND PARTICIPANTS: A cross-sectional observational study was undertaken in a single University Hospital...
September 27, 2016: European Urology
https://www.readbyqxmd.com/read/27678112/tumor-proliferation-and-diffusion-on-percolation-clusters
#16
Chongming Jiang, Chunyan Cui, Weirong Zhong, Gang Li, Li Li, Yuanzhi Shao
We study in silico the influence of host tissue inhomogeneity on tumor cell proliferation and diffusion by simulating the mobility of a tumor on percolation clusters with different homogeneities of surrounding tissues. The proliferation and diffusion of a tumor in an inhomogeneous tissue could be characterized in the framework of the percolation theory, which displays similar thresholds (0.54, 0.44, and 0.37, respectively) for tumor proliferation and diffusion in three kinds of lattices with 4, 6, and 8 connecting near neighbors...
October 2016: Journal of Biological Physics
https://www.readbyqxmd.com/read/27670795/magnetic-resonance-venous-volume-measurements-in-peripheral-artery-disease-from-elimit
#17
Hassan Kamran, Vijay Nambi, Smita Negi, Eric Y Yang, Changyi Chen, Salim S Virani, Panos Kougias, Alan B Lumsden, Joel D Morrisett, Christie M Ballantyne, Gerd Brunner
The relation between the arterial and venous systems in patients with impaired lower extremity blood flow remains poorly described. The objective of this secondary analysis of the Effectiveness of Intensive Lipid Modification Medication in Preventing the Progression on Peripheral Artery Disease Trial was to determine the association between femoral vein (FV) volumes and measurements of peripheral artery disease. FV wall, lumen, and total volumes were quantified with fast spin-echo proton density-weighted magnetic resonance imaging scans in 79 patients with peripheral artery disease over 2 years...
August 13, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27637439/laryngeal-cuff-force-application-modeling-during-air-medical-evacuation-simulation
#18
David Eisenbrey, Arthur B Eisenbrey, Patrick Pettengill
Endotracheal tubes are intended to protect the airway and assist with mechanical ventilation in sedated patients. The blood vessels of the tracheal mucosa can be compressed by high tracheal tube cuff pressures (> 30 cm H2O), leading to reduced mucosal blood flow with resulting ischemia and morbidity. Previous research showed a direct correlation between aircraft pressure altitude and the pressure reading from the tracheal cuff, with resulting pressures > 80 cm H2O at 10,000 ft. Standard practice is to periodically remove air from the cuff during ascent based on assumed increased pressure on the adjacent tracheal mucosa...
September 2016: Air Medical Journal
https://www.readbyqxmd.com/read/27634053/direct-puncture-embolization-of-the-internal-iliac-artery-during-cesarean-delivery-for-pernicious-placenta-previa-coexisting-with-placenta-accreta
#19
Zhenyu Chen, Ju Li, Jian Shen, Jiaxi Jin, Wei Zhang, Wan Zhong
OBJECTIVE: To evaluate direct puncture embolization of the internal iliac artery with hemostatic gelatin sponge particles to treat pernicious placenta previa coexisting with placenta accreta during cesarean delivery. METHODS: A retrospective study was conducted of data from women with pernicious placenta previa and placenta accreta who underwent direct puncture embolization of the internal iliac artery during cesarean delivery at a center in China between September 1, 2013, and February 28, 2015...
December 2016: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/27603732/highly-sensitive-raman-spectroscopy-with-low-laser-power-for-fast-in-line-reaction-and-multiphase-flow-monitoring
#20
Frank Braun, Sebastian Schwolow, Julia Seltenreich, Norbert Kockmann, Thorsten Röder, Norbert Gretz, Matthias Rädle
In process analytics, the applicability of Raman spectroscopy is restricted by high excitation intensities or the long integration times required. In this work, a novel Raman system was developed to minimize photon flux losses. It allows specific reduction of spectral resolution to enable the use of Raman spectroscopy for real-time analytics when strongly increased sensitivity is required. The performance potential of the optical setup was demonstrated in two exemplary applications: First, a fast exothermic reaction (Michael addition) was monitored with backscattering fiber optics under strongly attenuated laser power (7 mW)...
October 4, 2016: Analytical Chemistry
keyword
keyword
51004
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"