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Natalí Álvarez, Giovan F Gómez, Nelson Naranjo-Díaz, Margarita M Correa
The Arribalzagia Series of the Anopheles Subgenus comprises morphologically similar species or members of species complexes which makes correct species identification difficult. Therefore, the aim of this work was to discriminate the morphospecies of the Arribalzagia Series present in Colombia using a multilocus approach based on ITS2, COI and CAD sequences. Specimens of the Arribalzagia Series collected at 32 localities in nine departments were allocated to seven species. Individual and concatenated Bayesian analyses showed high support for each of the species and reinforced the previous report of the Apicimacula species Complex with distribution in the Pacific Coast and northwestern Colombia...
June 18, 2018: Infection, Genetics and Evolution
Davide Cao, Mauro Chiarito, Paolo Pagnotta, Bernhard Reimers, Giulio G Stefanini
Coronary artery disease (CAD) and aortic stenosis (AS) frequently coexist. The presence of CAD has been consistently associated with an impaired prognosis in patients undergoing surgical aortic valve replacement during short- and long-term follow-up. Accordingly, current guidelines recommend coronary revascularisation of all significant stenoses in patients undergoing surgical aortic valve replacement. Conversely, the management of concomitant CAD in patients with severe AS undergoing transcatheter aortic valve implantation (TAVI) is still a matter of debate...
May 2018: Interventional Cardiology
Mariana S Parahuleva, Bernhard Schieffer, Michael Klassen, Michael Worsch, Behnoush Parviz, Hans Hölschermann
BACKGROUND Factor VII-activating protease (FSAP) has a role in vascular inflammation and may have a role coronary artery disease (CAD). The aim of this study was to investigate the association between two naturally occurring single nucleotide polymorphisms (SNPs) in the FSAP gene and the risk of coronary artery disease (CAD). MATERIAL AND METHODS Of 733 patients, 173 patients had symptoms of angina, and 560 patients had CAD confirmed by coronary angiography. All patients were genotyped for SNPs of the FSAP gene, Marburg I (MI-SNP) and Marburg II (MII-SNP), using 5' exonuclease TaqMan assays...
June 21, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
Jeffrey H Lee, Leonard B Kaban, Michael J Yaremchuk
BACKGROUND: Le fort I maxillary osteotomies and sagittal split mandibular osteotomies are performed to correct significant dentofacial deformities. The multidimensional skeletal movements, particularly those of large magnitude may result in contour irregularities and facial imbalances. METHODS: Three dimensional images were reconstructed from computed tomographic (CT) scans in patients unhappy with their appearances after Le Fort I advancement and/or bilateral sagittal split osteotomies (BSSO)...
June 14, 2018: Plastic and Reconstructive Surgery
Nino Tsintsadze, Jelena Juloski, Michele Carrabba, Cecilia Goracci, Alessandro Vichi, Simone Grandini, Marco Ferrari
This study assessed push-out strength, cement layer thickness, and interfacial nanoleakage of luted fiber posts fabricated with computer-aided design/computer-assisted manufacture (CAD/CAM) technology after use of 1 of 3 scanning techniques, namely, direct scanning of the post space (DS), scanning of a polyether impression of the post space (IS), and scanning of a plaster model of the post space (MS). Thirty premolars were randomly assigned to three groups corresponding to the scanning technique. Posts were computer-designed and milled from experimental fiber-reinforced composite blocks...
2018: Journal of Oral Science
Ayse Seda Ataol, Gulfem Ergun
We evaluated the effects of three different surface treatments and two different bonding procedures on shear bond strength of resin composites to different computer-aided design/manufacturing (CAD/CAM) ceramics with or without thermocycling. The test specimens were prepared from three different CAD/CAM ceramics (Group A, IPS e.max CAD; Group B, IPS e.max ZirCAD; Group C, Vita Suprinity). They were divided into eight subgroups according to the surface treatment and bonding procedures. After resin composite was applied to the surfaces of all test specimens, they were stored in distilled water for 24 h at 37° C...
2018: Journal of Oral Science
Koichiro Fujisue, Suguru Nagamatsu, Hideki Shimomura, Takuro Yamashita, Koichi Nakao, Sunao Nakamura, Masaharu Ishihara, Kunihiko Matsui, Nobuyasu Yamamoto, Shunichi Koide, Toshiyuki Matsumura, Kazuteru Fujimoto, Ryusuke Tsunoda, Yasuhiro Morikami, Koshi Matsuyama, Shuichi Oshima, Kenji Sakamoto, Yasuhiro Izumiya, Koichi Kaikita, Seiji Hokimoto, Hisao Ogawa, Kenichi Tsujita
BACKGROUND: Chronic kidney disease (CKD) deteriorates the prognosis of patients undergoing percutaneous coronary intervention (PCI). Because coronary artery disease (CAD) is the major cause of death in CKD patients, cardiovascular risk reduction has been clinically important in CKD. We hypothesized intensive lipid-lowering with statin/ezetimibe attenuated coronary atherosclerotic development even in patients with CKD. METHODS: In the prospective, randomized, controlled, multicenter PRECISE-IVUS trial, 246 patients undergoing intravascular ultrasound (IVUS)-guided PCI were randomly assigned to receive atorvastatin/ezetimibe combination or atorvastatin alone (the dosage of atorvastatin was up-titrated to achieve the level of low-density lipoprotein cholesterol < 70 mg/dL)...
June 18, 2018: International Journal of Cardiology
B J Cheng, X M Nie, X L Zeng, H Yuan, X Ma, Y X Zhao, Y J Zhou
Objective: To investigate the correlation of the expression of platelet microRNA-223 (miR-223) with the degree of platelet activation and the severity of coronary lesions in patients with coronary artery disease (CAD). Methods: A total of 204 consecutive patients underwent coronary artery angiography (CAG) at Beijing Anzhen Hospital between April and December 2016 were enrolled. According to CAG results, all the patients were divided into two groups: 112 patients in CAD group and 92 patients in control group...
June 12, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
Amir Ali Amiri Moghadam, Seyedhamidreza Alaie, Suborna Deb Nath, Mahdie Aghasizade Shaarbaf, James K Min, Simon Dunham, Bobak Mosadegh
Pneumatically actuated soft robots address many challenges with interfacing with delicate objects, but these actuators/robots are still bulky and require many hours to fabricate, limiting their widespread use. This article reports a novel design and manufacturing method for ultrathin soft robots and actuators (∼70 μm) using a laser-cutting machine that cuts/welds sheets of thermoplastic polyurethane (TPU) from a 2D CAD drawing. Using this method, five different soft actuators (e.g., bending, rotating, contracting) are designed, fabricated, and characterized with both planar and nonplanar motions...
June 20, 2018: Soft Robotics
Anton R Kiselev, Alexey S Korotin, Olga M Posnenkova, Yulia V Popova, Mikhail D Prokhorov, Vladimir I Gridnev
Objective: In European Society of Cardiology/European Association for Cardio-Thoracic Surgery (ESC/EACTS) guidelines, six indications have been proposed for making a decision on myocardial revascularization in patients with stable coronary artery disease (CAD). Our aim was to study a discrepancy between the actual clinical situation and ESC/EACTS indications on performing the revascularization in patients with CAD in Russia. Design and setting: We used retrospective clinical data on patients with stable CAD enrolled in the 2012-2015 Russian Registry of Hypertension, Coronary Artery Disease, and Chronic Heart Failure...
June 19, 2018: International Journal for Quality in Health Care
Fabio Mangiacapra, Edoardo Bressi, Alessandro Sticchi, Carmine Morisco, Emanuele Barbato
The presence and extent of myocardial ischemia are the major determinants of prognosis in patients with coronary artery disease (CAD). Unlike coronary angiography alone, fractional flow reserve (FFR) has enabled interventional cardiologists to accurately determine whether coronary atherosclerotic plaques are responsible for myocardial ischemia, and therefore deserve to be revascularized. Areas covered: An overview on the role of FFR in the diagnosis and treatment of coronary artery disease, as well as the potential related controversies is provided...
June 20, 2018: Expert Review of Cardiovascular Therapy
Zuhair Iftikhar, Olli Lahdenoja, Mojtaba Jafari Tadi, Tero Hurnanen, Tuija Vasankari, Tuomas Kiviniemi, Juhani Airaksinen, Tero Koivisto, Mikko Pänkäälä
Cardiac translational and rotational vibrations induced by left ventricular motions are measurable using joint seismocardiography (SCG) and gyrocardiography (GCG) techniques. Multi-dimensional non-invasive monitoring of the heart reveals relative information of cardiac wall motion. A single inertial measurement unit (IMU) allows capturing cardiac vibrations in sufficient details and enables us to perform patient screening for various heart conditions. We envision smartphone mechanocardiography (MCG) for the use of e-health or telemonitoring, which uses a multi-class classifier to detect various types of cardiovascular diseases (CVD) using only smartphone's built-in internal sensors data...
June 19, 2018: Scientific Reports
Burcu Gunal, M Mutahhar Ulusoy
OBJECTIVE: This study evaluated the optical properties of contemporary monolithic CAD-CAM materials with different chemical compositions. MATERIALS AND METHODS: Totally, 210 rectangular-shaped, A2 shade specimens (12 × 14 mm) were fabricated from VITA Suprinity T, VITA Enamic T, VITA Mark II, GC Cerasmart LT, Lava Ultimate LT, IPS e.max CAD LT and Prettau Anterior blocks and polished to thicknesses of 0.5 ± 0.01 and 1.0 ± 0.01 mm (n = 15 each material)...
June 19, 2018: Journal of Esthetic and Restorative Dentistry
Shilpa Sharma, Puja K Mehta, Reza Arsanjani, Tara Sedlak, Zachary Hobel, Chrisandra Shufelt, Erika Jones, Paul Kligfield, David Mortara, Michael Laks, Marcio Diniz, C Noel Bairey Merz
BACKGROUND: The utility of exercise-induced ST-segment depression for diagnosing ischemic heart disease (IHD) in women is unclear. HYPOTHESIS: Based on evidence that IHD pathophysiology in women involves coronary vascular dysfunction, we hypothesized that coronary vascular dysfunction contributes to exercise electrocardiography (Ex-ECG) ST-depression in the absence of obstructive CAD, so-called "false positive" results. We tested our hypothesis in a pilot study evaluating the relationship between peripheral vascular endothelial function and Ex-ECG...
June 19, 2018: Clinical Cardiology
G-M Li, C-L Zhang, R-P Rui, B Sun, W Guo
OBJECTIVE: This paper aims at screening the common differential genes of coronary atherosclerotic heart disease (CAD) and ischemic cardiomyopathy (ICM), and to conduct pathway analysis and protein-protein interaction (PPI) network analysis for the differential genes. MATERIALS AND METHODS: The CAD and ICM datasets were collected from the Gene Expression Omnibus (GEO) database for human tumors to extract data components of peripheral blood RNA of patients and normal people in GSE71226 and GSE9128 chips; "limma" package of "R" software was used to screen the differential genes, and "pheatmap" package was applied to construct heat maps for the differential genes; Cytoscape, Database for Annotation, Visualization and Integration Discovery (DAVID) and String platforms were utilized for PPI network analysis, Genome Ontology (GO) analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis on the selected differential genes...
June 2018: European Review for Medical and Pharmacological Sciences
Ann Kristin Bjørnnes, Monica Parry, Marit Leegaard, Ana Patricia Ayala, Erica Lenton, Paula Harvey, Judith McFetridge-Durdle, Michael H McGillion, Jennifer Price, Jennifer Stinson, Judy Watt-Watson
Symptom recognition and self-management is instrumental in reducing the number of deaths related to coronary artery disease (CAD) in women. The purpose of this study was to synthesize qualitative research evidence on the self-management of cardiac pain and associated symptoms in women. Seven databases were systematically searched, and the concepts of the Individual and Family Self-Management Theory were used as the framework for data extraction and analysis. Search strategies yielded 22,402 citations, from which 35 qualitative studies were included in a final meta-summary, comprising data from 769 participants, including 437 (57%) women...
June 1, 2018: Qualitative Health Research
Norman A Orabi, Leslie E Quint, Kuanwong Watcharotone, Bin Nan, David M Williams, Karen M Kim
The aim was to compare computed tomography (CT) features in acute and chronic aortic dissections (AADs and CADs) and determine if a certain combination of imaging features was reliably predictive of the acute versus chronic nature of disease in individual patients. Consecutive patients with aortic dissection and a chest CT scan were identified, and 120 CT scans corresponding to 105 patients were reviewed for a variety of imaging features. Statistical tests assessed for differences in the frequency of these features...
June 18, 2018: International Journal of Cardiovascular Imaging
Harutoyo Hirano, Renjo Takama, Ryo Matsumoto, Hiroshi Tanaka, Hiroki Hirano, Zu Soh, Teiji Ukawa, Tsuneo Takayanagi, Haruka Morimoto, Ryuji Nakamura, Noboru Saeki, Haruki Hashimoto, Shogo Matsui, Shinji Kishimoto, Nozomu Oda, Masato Kajikawa, Tatsuya Maruhashi, Masashi Kawamoto, Masao Yoshizumi, Yukihito Higashi, Toshio Tsuji
This paper proposes a novel non-invasive method for assessing the vascular endothelial function of lower-limb arteries based on the dilation rate of air-cuff plethysmograms measured using the oscillometric approach. The principle of evaluating vascular endothelial function involves flow-mediated dilation. In the study conducted, blood flow in the dorsal pedis artery was first monitored while lower-limb cuff pressure was applied using the proposed system. The results showed blood flow was interrupted when the level of pressure was at least 50 mmHg higher than the subject's lower-limb systolic arterial pressure and that blood flow velocity increased after cuff release...
June 18, 2018: Scientific Reports
Fereshteh Ghaderi, Hossein Samim, Faeze Keihanian, Seyed Ali Danesh Sani
BACKGROUND: It is well recognized that cardio- vascular risk factors lead to histological and functional changes in aorta, and aortic stiffness is the best predictor of cardiovascular morbidity and mortality. In this study we evaluated the relation of a less evaluated echocardiographic parameter of aortic stiffness, aortic propagation velocity (APV) with the presence and severity of CAD. METHODS: This cross sectional study was conducted from May 2015 to March 2016 in Imam Reza hospital, Mashhad, Iran...
June 19, 2018: BMC Cardiovascular Disorders
Olga Valenzuela, Xiaoyi Jiang, Antonio Carrillo, Ignacio Rojas
Computer-Aided Diagnosis (CAD) represents a relevant instrument to automatically classify between patients with and without Alzheimer's Disease (AD) using several actual imaging techniques. This study analyzes the optimization of volumes of interest (VOIs) to extract three-dimensional (3D) textures from Magnetic Resonance Image (MRI) in order to diagnose AD, Mild Cognitive Impairment converter (MCIc), Mild Cognitive Impairment nonconverter (MCInc) and Normal subjects. A relevant feature of the proposed approach is the use of 3D features instead of traditional two-dimensional (2D) features, by using 3D discrete wavelet transform (3D-DWT) approach for performing feature extraction from T-1 weighted MRI...
May 7, 2018: International Journal of Neural Systems
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